Phys Ther
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Transcript of Phys Ther
Phys Ther. 2011 August; 91(8): 11981207.
Published online 2011 May 26. doi: 10.2522/ptj.20100372PMCID: PMC3145896
Associations Between Physical Performance and Executive Function in Older Adults With Mild Cognitive Impairment: Gait Speed and the Timed Up & Go Test
Ellen L. McGough, Valerie E. Kelly, Rebecca G. Logsdon, Susan M. McCurry, Barbara B. Cochrane, Joyce M. Engel, Linda TeriAuthor information Article notes Copyright and License information This article has been cited by other articles in PMC.
Go to:Abstract
Background
Older adults with amnestic mild cognitive impairment (aMCI) are at higher risk for developing Alzheimer disease. Physical performance decline on gait and mobility tasks in conjunction with executive dysfunction has implications for accelerated functional decline, disability, and institutionalization in sedentary older adults with aMCI.
Objectives
The purpose of this study was to examine whether performance on 2 tests commonly used by physical therapists (usual gait speed and Timed Up & Go Test [TUG]) are associated with performance on 2 neuropsychological tests of executive function (Trail Making Test, part B [TMT-B], and Stroop-Interference, calculated from the Stroop Word Color Test) in sedentary older adults with aMCI.
Design
The study was a cross-sectional analysis of 201 sedentary older adults with memory impairment participating in a longitudinal intervention study of cognitive function, aging, exercise, and health promotion.
Methods
Physical performance speed on gait and mobility tasks was measured via usual gait speed and the TUG (at fast pace). Executive function was measured with the TMT-B and Stroop-Interference measures.
Results
Applying multiple linear regression, usual gait speed was associated with executive function on both the TMT-B (=0.215, P=.003) and Stroop-Interference (=0.195, P=.01) measures, indicating that slower usual gait speed was associated with lower executive function performance. Timed Up & Go Test scores (in logarithmic transformation) also were associated with executive function on both the TMT-B (=0.256, P Literature > PubMed Central (PMC)Write to the Help Desk
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145896/?report=classic