perspectives 2008

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perspectives Liverpool 2008

description

The poster session with a difference - recently featured on BBC Radio 4's Leading Edge. 33 young scientists (PhD - Postdoc) are challenged to communicate their research to the general public and explore the social implications of their research.

Transcript of perspectives 2008

  • perspectivesLiverpool2008

  • perspectivesGeorgina Humphreys (2008 Winner) ...............................3Nick Bredenkamp ..............................................................4Jamie Brown .......................................................................5Sarah Brown .......................................................................6Maria Canal .......................................................................7Paolo Carampin ................................................................8Julia Collins .........................................................................9Ian Couchman ................................................................10Laura Crack .....................................................................11Olga DenBesten ..............................................................12Berenice Golding ............................................................13Alison Graham .................................................................14Jennifer Hannant ........................................................... 15Alana James .................................................................. 16Gaurav Khanna ............................................................. 17Daphne Kounali ............................................................. 18Katherine Leney ............................................................. 19Jad Marrouche .............................................................. 20Sarah McBurney ............................................................. 21Satomi Miwa ................................................................... 22Charlie Mydlarz .............................................................. 23Ciprian Plostinar ............................................................. 24Sara Rafice ..................................................................... 25Ruby Raheem ................................................................ 26Luc Rock ......................................................................... 27Steven Rossington .......................................................... 28Lori Snyder ....................................................................... 29Mury Thian ....................................................................... 30Sarah Tomlinson ............................................................. 31Elizabeth Tunbridge ....................................................... 32Gert Verheyden ............................................................. 33Alison Wallace ................................................................ 34Tom Wells ........................................................................ 35 Paul Williams ................................................................... 36

    contents

  • Its not all about DollySociety and stem cells Ethics and stem cells

    Boosting the immune system from stem cells

    Immune boost after bone marrow transplant

    Fighting autoimmune diseases e.g. diabetes

    Better vaccine responses

    Organ transplant tolerance

    The thymus shrinks as we age

    Potential clinical benefits

    Can we grow a thymus from stem cells?

    Fewer T cells are madeHigher rates of infection Decreased response to vaccinesIncreased autoimmunity

    Thymic epithethialstem cells from donor tissue

    A whole, functional organ from stem cells

  • 600,000 people lie on the autism spectrum in the UK. That is nearly 1% of the whole population.

    We must start learning now...

    Learning in autismTry to describe the many rules of English language or the many

    movements you make when kicking a football. Do you remember

    sitting down and learning when you should speak and when

    you should listen; when you should laugh and when you should

    frown; or when you should look someone in the eye and when

    you should not?

    Many language, movement and social skills such as these are

    difficult to describe and are typically learned without trying. This

    suggests that they are easy for people to learn. Curiously, autistic

    individuals have trouble with precisely these skills.

    Yet, sometimes they can learn effortlessly where other people

    have great difficulty. For example, some autistic individuals have

    been able to tell the day of the week for any date many years

    into the future or to memorise whole train timetables.

    Clearly, the way autistic individuals learn is unusual. Studying

    their learning patterns in carefully controlled tasks allows us to

    establish why this might be so.

    What is at stake?Autism fundamentally affects social interaction and

    communication. As a result, autistic individuals and their families

    can face profound challenges in completing apparently mundane

    everyday tasks.

    Learning how to overcome such challenges is incredibly

    important for autistic peoples quality of life. Understanding the

    strengths and weaknesses of their learning styles can help future

    treatments and interventions to achieve this.

    This research can also help us understand how learning processes

    typically develop.

    Why must we be cautious?The disorder spans a wide spectrum of behaviour. However, we are only able to work with more able individuals. Will our findings generalise?

    The disorder is the product of abnormal development throughout childhood. Yet, we only work with an individual for a few hours. Are we able to incorporate this developmental complexity?

    Individuals with autism experience the world very differently

    to other people. Are we sure they are willing participants and not distressed by our tasks?

    By being vigilant of such pitfalls, we have made a successful start: we now know that unintentional learning is not always impaired in autism. On a range of our tasks children with and without autism performed equivalently. We must keep learning.

  • Hi, Im the Nanodetective. Im on the hunt for a

    target within the body that may

    hold some important information.....

  • Mind the clock

    We all have a clock in the brain that controls daily changes in: Sleep,

    Hormones, Temperature, Blood pressure, Digestion

    Modern life disturbs the

    clock:Shiftwork,Jet-lag

    Leading to sleep problems, depression,

    cancer, accidents

    My research:

    HOW CAN WE FIX A BROKEN CLOCK?

  • NanoparticlesNanoparticles

    are "are "nanonano" object ("" object ("nanonano" originates from the Greek word meaning " originates from the Greek word meaning dwarf: one dwarf: one nanometrenanometre

    is one billionth of a is one billionth of a metremetre

    and is tens of thousands of times and is tens of thousands of times smaller than the width of a human hair) that can host a drug, prsmaller than the width of a human hair) that can host a drug, protecting it and otecting it and transporting it until a release takes place. transporting it until a release takes place.

    With smart With smart nanoparticlesnanoparticles, the release of the encapsulated , the release of the encapsulated payload (for instance an antipayload (for instance an anti--inflammatory drug) is not inflammatory drug) is not unspecific, but on the contrary it takes place only in unspecific, but on the contrary it takes place only in response to a specific signal (e.g.: oxidizing conditions, likeresponse to a specific signal (e.g.: oxidizing conditions, like

    Body with Body with inflammedinflammedtissuetissue

    Injection of smart Injection of smart nanoparticlesnanoparticles

    The body is The body is healthy again!healthy again!

    in in inflammedinflammed

    tissues), that tissues), that

    triggers a complete triggers a complete

    rearrangement of the rearrangement of the

    nanoparticlesnanoparticles

    and the release and the release of their encapsulated payload.of their encapsulated payload.

    My research has been shaped by the My research has been shaped by the need of the society for systems that need of the society for systems that can target pathological environment can target pathological environment in a specific way, trying to provide a in a specific way, trying to provide a tool that can improve the treatment tool that can improve the treatment of common diseases.of common diseases.

    and specifically and specifically release their release their encapsulated encapsulated

    drugdrug

    Smart Smart nanoparticlesnanoparticles

    reach reach their target (their target (inflammedinflammed

    tissue)tissue)

  • CONTROL is the study of how wecan influence the behavior of a

    SYSTEM with certain INPUTS.

    SYSTEM: for example a chemicalfactory, a bouncing ball, a space

    rocket or a fridge.

    INPUT: if the system is a spacerocket the inputs might be how

    much the thrusters are turned on.

    the control centre

    advantages?

    ETHICS: If we can mix freeradicals better before they reach theozone layer, we could release a lot

    more. But is this really a goodidea?

    DANGER: If we want to mix reallywell, we might design a factory

    that is very difficult toCONTROL. This means that if thecontroller breaks humans will not

    be able to stabilize it...

    if we can mix fluids quickly andwithout much effort, the process ismore efficient. So if the SYSTEM

    is a chemical factory, we couldmake more chemicals in a dayand using less electricity, so

    reducing the CARBONFOOTPRINT and the PRICE OF

    PRODUCTS.

    many applications need to mix fluids e.g. abeer factory, a microprocessor cooler or a paintmaking facility. In one approach, the fluidsto be mixed are put together and shaken and

    left. This uses lots of energy and is timeconsuming. It cannot detect poorly mixed

    regions and choose to focus the effort on justthis space.

    shall we mix thingsup a little?

    can we CONTROL how mixed two fluids are by looking how they arearranged and then stirring them? The SYSTEM is the two fluids, theINPUTS are how much we stir them and in what way. The aim is to

    mix the fluids together as quickly as possible using the least amountof effort.

    stirred not shaken, please

    this work is EPSRC funded whichis the UK Government's leadingfunding agency for research andtraining in engineering and the

    physical sciences

    financial district

    stirring up trouble

  • Phew! Its just harmless dust mite

    particles again

    Immune Cell

    Another One Bites the DustHouse Dust Mite Immunotherapy

    What Happens In the Body?

    Immunotherapy - Costs and BenetsBenets

    Less medication

    Reduction in symptoms

    Quality of life

    Principles can be applied to: - cancer treatment- vaccine development

    Costs

    Adverse reaction

    Long term benets requires up to several years of treatment

    Relapse?

    Financial costs

    If you have any questions or want any further information please ask me!

    What is House Dust Mite Allergy?House dust mites are insects that live in household dust, as well as sofas, carpets and mattresses

    They are everywhere!

    People most affected:- live in developed countries e.g. UK and USA- are all ages, but especially children- are those who are susceptible due to their genetic make up

    In some people, exposure to house dust mites causes an allergic reaction

    Immunotherapy is the articial manipulation of the immune system as a form of therapy for allergies.

    What is Immunotherapy?

    Particles that cause an allergic response in susceptible people can be administered in a way that the body gets used to or is tolerant to the protein.

    Allergic responses can result in hay fever,eczema or asthma, or a combination of these dis-eases.

    These particles can belong to anything that causes allergy including pollen, insects, pet hair and, in my research particularly, house dust mites and allergic eczema in the skin.

    Did You Know?The Latin name for house

    dust mite literally means skin eater as house dust mites feed on the shedded human

    skin that makes up household dust.

    Urghh!!!

    The treatment starts by giving very low numbers of the very particles that cause the allergic response, in gradually increasing doses. These are given by a series of injections over several months or even years.

    This can result in several symptoms, including itchy and painful eczema in the skin.

    ATTACK!!

    Immune Cell

    Dust mites release particles into the environment, which enter the body and are recognised by some immune cells as dangerous invaders.

    My Research and the Role of Society

    Compared to other allergies, house dust mite immunotherapy is not as advanced. We are trying to determine a new section of house dust mite protein that causes allergic eczema in a wide range of people. Without eczema patients donating blood and skin samples, my research would come to a halt so THANK YOU!!

    Immune cells tolerate the presence of house dust mite particles, and dont launch an immune attack, so the bodyis unaffected.

  • Speakers cornerIMAGES:PEB COMPENDIUM OF EXEMPLARY EDUCATIONAL FACILITIES: 3RD EDITION, WWW.OECD.ORG;BEING INVOLVED IN SCHOOL DESIGN: A GUIDE,WWW.CABE.ORG.UK;THE YOUNG DESIGN PROGRAMME 2006-2007,WWW.THESORRELLFOUNDATION.COM;KINGSWOOD SPECIALIST ARTS COLLEGE, STAGE C REPORT.

  • Uncovering the magic... ...and re-building life

    In the past...What is systems biology?

    Now In the future...

    Microbe

    Gene(s) for X inserted into chromosome

    Protein Xproduced

    XY

    K

    BAZ

    L

    And synthetic biology?

    A new kind of science

    We will be able to build elaborate predictive models (in the computer for example, of the liver) to aid design of

    experiments.

    How will society be affected?

    Organ modelling e.g. heart, liver, gut, skin. Used to predict safety of medicines and cosmetics. Helps reduce the number of animals used in drug testing. Saves time and money. Cheaper drugs.

    Image shows electrical activity in the heart during the onset of cardiac arrest and is courtesy of Dr R Clayton (University of Sheffield). Funding from the British Heart Foundation.

    Biofuels e.g. hydrogen gas from microbes. Use bacteria to convert feedstocks to fuels (e.g. bioethanol).

    BioremediationEngineer microbesto degrade pollutants.

    Diagnosis of disease

    Clinical and genetic information combined and used to identify disease bio-markers. Aids future diagnoses. Prevent disease before it happens?

    Bioterrorism Risk of microbes being engineered for malicious use. Needs regulation.

    Biomaterials/bioplasticsUse microbes to produce synthetic materials or to make a natural product more readily available (e.g. spider silk).

    Personalised healthcare.Match treatment to an individuals genetic make-up.

    Tissue engineeringUse microbes to produce a scaffold on which to grow human skin.

    Why now?Biological techniques can collect large

    amounts of information, imaging techniques have improved and computer power has expanded

    enormously.

    What can computer models do?Identify gaps in knowledge and predict the outcome of

    experiments. As a result, we can design better experiments.

    Models can be used to understand the factors contributing to complex disease e.g. diabetes, obesity, hypertension, cancer,

    ageing and also infectious disease.

    IssuesWhat if the model is

    wrong?Will it blur the distinction

    between machines and life forms?

    What about patient confidentiality?

    Real life

    There are already computer

    models of diabetes, obesity,

    rheumatoid arthritis and asthma

    being used in the design of

    clinical trails. A heart model has

    been used to assess drug safety.

    I know all about protein X and protein Y and

    what they do together.

    Im a computer modeller. I can predict how Y interacts with K and help

    you design better experiments to save time and money.

    I knowabout protein K and

    how it interacts with X, but what does it do

    with protein Y? I must do an experiment.

    Production of medicines Maximise production efficiency of existing medicines or find new production methods. e.g. use engineered microbes to produce an anti-malarial drug at a lower cost than extracting it from plants. Not climate-dependent. Allows land re-use Regional unemployment?

  • Making technology come alive

    Nanotechnology is the power of the small. So what is nano? One nanometre is one billionth of a metre. This is effectively the size of a marble compared to the size of the earth. Nanotechnology is a way of creating unique new devices on the nanoscale.

    DNA is the ABC of life. We can manipulate the body's expertise on self-assembly for use in technology . These building blocks can be used as a scaffold to build our own technological structures onto.

    Nanotechnology

    Nanotechnology >

    iNanotechnology

    DNA

    Interface

    Ethics should we?

    How can the building blocks of life make the technology of the future?

    These new materials will be much smaller and faster than our current technology. However, to make things smaller we need to the help of something which is already on that scale. DNA can be used as it is measured on the nanoscale so effectively becomes an interface between biology and technology.

    Should we be making technology come to life?In our research, we are not using DNA to create any new biology

    Our technology will offer many applications that can help improve tools that can be used from electronics to medicine and from crime to the environment

    However, with new technology, operating standards need to be adhered to, to ensure this new nanotechnology is safe and does not get out of control

    Nanotechnology >

  • Even when itEven when itEven when itEven when its s s s GreyGreyGreyGrey, Concrete is , Concrete is , Concrete is , Concrete is GreenGreenGreenGreen

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    What is Concrete?Concrete is a common construction material. It plays a key role in meeting society's needs for housing and basic infrastructure like schools, hospitals, malls, bridges and airports. In fact, concrete serves us everyday!

    What Researchers Do to Answer These Questions?

    Solution: Engineering

    Further Informationwww.global-greenhouse-warming.com/cement-CO2-emissions.html

    www.concretethinker.com/technicalbrief/Concrete-Cement-CO2.aspx

    Our Responsibility: Be SustainableIssue: Global Warming Climate Change

    Cement Industry is at Centerof Climate Change DebateThe New York Times, October 26, 2007

    100 months to stop overheatingThe Guardian, August 1, 2008

    OPEN Questions?

    Concrete: Constructions Sustainable Option7th International Congress

    8 10 July 2008 I Dundee, Scotland

    Educate and Communicate

    Lab Work

    Field Work

    Prediction and Risk Assessment

    Aggregates WaterSandCement

    Concrete is made from the cement which is the main binding agent that holds sand and other aggregates together in a hard, stone-like mass.

    TYPICAL INGREDIENTS OF CONCRETE

    Smoke from a Cement Plant, NYT 25.10.07

    Please ask me more

    References(1) Progress Report on The Cement Sustainability Initiative, June 2005, World Business Council for Sustainable Development.(2) Industrially Interesting Approaches to low-CO2 cements, Gartner E, Cement and Concrete Research, Vol 34 (9), Sept 2004, pp 1489 1498.

    Concrete: The second most commonly used material on plant Earth after water.(1)

    Construction Worker Pouring Concrete

    Cement production for concrete accounts for 5% of the global carbon dioxide emissions.(2)

    Cement: A Global Pollutant

    Could concrete be produced without cement?

    Could this be economically and environmentally valuable?

    Could these structure be made safe then?

    Could waste from other industries be a substitute for cement?

    Could any other material replace cement in concrete?

    Could results be adopted globally?

    Said, Said,

  • The best school

    Should we abandon school league tables?

    SCHOOL LEAGUE TABLESThe IMPLICIT assumption in the publication

    of tables with school test results each year

    is that the schools position in these tables

    is a measure of quality of their educational

    provision. In fact two different statistics

    are available.

    Averages and Value-Added scores.Comparing simple averages of test scores

    For each school is similar to comparing

    apples with oranges. These will mainly

    reflect the quality of their pupils prior

    attainment and socio-economic

    background rather than true differences

    in the quality of schooling they provide.

    The value-added scores are test score

    averages adjusted for individual pupil

    and school characteristics that can affect

    performance in school tests. So, these

    averages are better for comparisons.

    The uncertainty in STATISTICSAll these statistics are ESTIMATES of how

    most pupils in each school did in their

    tests. We also need to know how good

    these estimates are. Good estimates

    are those that do not vary very much when

    we calculate them repeatedly

    e.g. from year to year. This uncertainty can

    make the comparisons more difficult

    e.g. consider a school with a higher

    average than another but both having

    a lot of variability. Then we cannot tell

    which is best. The uncertainty that

    accompanies official statistics is NOT

    widely published.

    SCHOOL CHOICEOur studies show that there are many

    factors that affect the performance of

    children in tests that we can not collect

    or even measure. This increases the

    uncertainty of our estimates so much

    that most schools are indistinguishable.

    This in turn reduces the accuracy of

    our predictions.

    Our studies show that the exam

    performance of pupils starting secondary

    school, will be a poor guide to performance

    at their GCSEs. So, school league tables

    are not fit for the purpose of informing

    parental choices.

    Markets in educationThe school choice political agenda has

    a broad aim of raising standards

    in ALL schools. The idea is that

    competitive pressure is applied to schools

    when parents see a better chance for

    their children elsewhere. This potential loss

    of children and funds will push schools

    to raise their standards. If this worked, it

    would be beneficial to all pupils.

    Our research in education suggests that:

    Poor children are less likely to go to

    good schools. Half of secondary school

    pupils do not attend their local school.

    BUT

    Is our school system a system of

    equal choice? If choice is unequal, do

    poor pupils get a fair deal?

    How should school places be allocated?

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    High Energy PhysicsWhat is everything made of?

    How does it all interact?

  • Population (in millions)

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    (Japanese females. Source: U.S. Census Bureau, International Data Base)

    For a century and a half, our life expectancy has been increasing by 2.5 years per decade which is 5 hours a day.

    Is there a limit to the human life span? Do longer

    lives mean more diseases? Scientists will develop a magic bullet to

    cure ageing.?

    How will we use the extra time we gain? Can we afford increasing life spans? What will the

    future society become like?

    The mechanisms of ageing and longevity are intriguing and challenging themes being sought by human beings since an ancient era. But now has become more than just a matter of scientific curiosity. Age is the largest single risk factor for many diseases, and often treatment of one disease only reveals the occurrence of another. Therefore, understanding the nature of ageing and why aged cells and organs are more susceptible to diseases are crucial for healthy ageing and increasing life span.

    My research focus are the roles of oxidative stress on the ageing process. Oxygen free radicals are produced as by-products during normal metabolism as well as under stressful conditions. They can sometimes overwhelm bodys antioxidant systems, causing oxidative stress. Many molecules such as DNA, proteins and lipids are susceptible to damage under oxidative stress, and accumulation of such damage is hypothesised to result in decline of tissue function and lead to ageing. How are oxygen free radicals produced? What are the regulators? Can we control free radical generation and change the pattern of ageing? Can damaged molecules be turned over more effectively? We look for the answers to these questions by utilising a number of different model systems as well as mathematical modelling.

    Ageing is malleable.Longevity and health span are influenced not only by genes, but also by environmental factors such as nutrition, lifestyle, socioeconomic status and attitude. So how does ageing occur?

  • We want to turn your phone into a cutting edge recording device enabling you to capture the sounds around you and express your opinions of them

    What are we doing and why?

    With 28 million people living in areas where their quality of life is affected negatively by noise levels, there is a drive to design spaces that are truly appreciated in terms of their sound environment

    YOUR SONIC ENVIRONMENT

    What are you listening to?birds singing, roadworks drilling, mobiles ringing, doors

    slamming, car radios booming, smokers coughing, babies

    crying, cats purring, keys jangling, glasses clinking, speakers

    pumping, footsteps falling, dogs barking, kids shouting, balls

    bouncing, thunder clapping, rain pouring, lightning cracking, cars

    passing, buses grumbling, hands clapping, glass breaking,

    fingers tapping, fans blowing, engines roaring, drums banging

    A soundscape is all the sound around you wherever you are

    Whether on a conscious or subconscious level you are affected by the sound around you,

    which can make you feel comfortable, productive and happy, or uneasy, distracted and stressed

    We need to know the impact and effect these environments have on your everyday life so we can work to make them sound better

    The appreciation of soundscapes can be affected by age, gender, cultural background or education, or a combination of all of these factors

    With your help we can make the world sound better

    Mobile phones will be used because of their popularity in society, widespread use and sophisticated processing power contained within their small designs

    By determining the influential characteristics of the soundscape we can predict the effect it will have on people, giving us new insights into how humans react to their sonic environments

  • The World of Particle AcceleratorsParticle accelerators are some of the most amazing scientific tools known

    to man. These gigantic instruments speed up and increase the energy of a beam of particles using electric fields to accelerate them and magnetic fields to steer and focus them. At CERN near Geneva, in the new LHC ac-celerator, protons will be accelerated to very high energies and they will

    travel at 99.9% of the speed of light. Thats more than 7 times around the Earth in just 1 second.

    How does it affect me?Many accelerators are being used for research that has a direct impact on our daily lives. Many of the everyday products we take for granted from chocolate to cosmetics, from revolutionary drugs to computers have been improved or developed using particle accelerators.

    ?Why Fundamental Science?Some areas of fundamental research seem remote from everyday life and unlikely to bring immediate and practical applications. Are they worth the effort in human and material resources? Fundamental science is where new ideas and methods begin that later become commonplace. The research may take us away from everyday life, but because it continually pushes the boundaries in thinking and technology, it is a springboard for many new developments.Science needs the space for curiosity and imagination!

    Fundamental ResearchIn particle accelerators, particles of higher and higher energies are collided head-on or fired at fixed targets in order to answer the latest questions concerning the ultimate structure of matter. Each leap in energy gives a fascinating insight into the particle world, showing detail never seen before. The latest and largest accelerator ever built, the LHC@CERN, will answer some intriguing questions:

    What is the origin of mass? What is 96% of the Universe made of? What happened to the antimatter? What are the secrets of the Big Bang? Are there other worlds hidden in extra dimensions of space?

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    Protein rich food

    Magnification of protein food

    My Enzyme

    ENERGY

    Enzymes break proteins to release

    Energy

    Why research the Human Body?

    How my research affects YOU?

  • MAKING BABIES ARTMAKING BABIES ARTMAKING BABIES ARTMAKING BABIES ART ficiallyficiallyficiallyficially

    Injecting sperm into an egg (ICSI)

    What Nature does with 20 million healthy sperms, medical technology (ART) can achieve with one. But How healthy are these ART sperms?

    Conventional In-Vitro Fertilisation (IVF)

    Artificial Reproductive Technology (ART)When the number of healthy sperm cells are low, thethe egg can be fertilised in a clinic by dumping millions of sperms on an egg placed in a glass dish

    Laser screening of live sperms for DNA damage

    Healthy DNA

    Broken DNA

    Laser Probe

    The reality of having a baby is

    a Grim Fairy Tale: The race is not merely to the swift or strong sperms. Often it is a

    tale of endurance, patience, determination

    and teamwork.

    1 in 6 couples cant have babies

    ?

    DNA healthof eggs and

    sperms used in ART become critical for

    severe cases of infertility

    It takes a healthy egg and 20 million healthy

    sperms to make a baby naturally

    Girls are born with life supply of eggs whereas sperms are

    regenerated every 90 days

    Test tube babies help men and

    women with mild cases of infertility

    Reproductive cells age as men and women age.

    Environment, stress & illness effect

    cell health

    DNA fingerprints

    Laser Probe

    Sperm injection helps

    men with severe infertility, but the

    sperm health becomes a major concern

  • Tracking Pollutants: Searching for FingerprintsIsotopes in Action

    Polluted Rivers raise Questions such as:

    Where did the pollutant come from?

    What happens to a pollutant?

    How much did a specific pollutant source contribute to the pollution?

    Scientific Tool used:

    measurement of the isotopic composition of a compound (e.g. nitrate)

    What is an isotope?

    a chemical element (e.g. Nitrogen, N) can have different

    14 15isotopes (e.g. N, N), each having a different mass

    an isotopic composition is like a fingerprint, it helps to identify sources of pollution

    Other Applications of Isotopes:

    sustainability

    climate change

    food authenticity - traceability

    sports doping

    Moral and Financial Dilemmas:

    economic growth versus environmental protection

    fingerpointing at a particular group

    Impacts on Society:

    provides data to reduce and to prevent pollution

    influences environmental policies

    raises awareness of sources of pollution

    Pollutant Source:Manure

    Pollutant Source:Sewage

    Pollutant Source:fertilizer

  • CGATTAAAGATAGAAATACACGATGCGAGCAATCAAATTTCATAACATCACCATGAGTTTGATCCAAAGCATGAGTGTTTACAATGTTTGAATACCTTATACAGTTCTTATACATACTTTATAAATTATTTCCCAAGCTGTTTTGATACACACACTAACAGATACTCTATAGAAGGAAAAGTTATCCACTTATGCACACTTATACTTTTTAGAATTGTGGATAATTAGAAATTACACACAAAGTTATACTATTTTTAGCAACATATTCACAGGTATTTGACATATAGAGAACTGAAAAAGTATAATTGTGTGGATAAGTCGTCCAACTCATGATTTTATAAGGATTTATTTATTGATATTTACATAAAAATACTGTGCATAACTAATAAGCAGGATAAAGTTATCCACCGATTGTTATTAACTTGTGGATAATTATTAACATGGTGTGTTTAGAAGTTATCCACGGTTGTTATTTTTGCCAAAGCGTACAATCCATTATTTATCTATGGAGGTGTTGGTTTAGGAAAAACCCATTTAATGCATGCCATTGGTCATCATGTTTTAGATAATAATCCAGATGCCAAAGTGATTTACACATCAAGTGAAAAATTCACAAATGAATTTATTAAATCAATTCGTGATAACGAAGGTGAAGCTTTCAGAGAAAGATATCGTAATATCGACGTCTTATTAATCGATGATATTCAGTTCATACAAAATAAAGTACAAACACAAGAAGAATTTTTCTATACTTTTAATGAATTGCATCAGAATAACAAGCAAATAGTTATTTCGAGTGATCGACCGCCAAAGGAAATTGCACAATTAGAAGATCGATTACGTTCGCGCTTTGAATGGGGGCTAATTGTTGATATTACGCCACCAGATTATGAAACTCGAATGGCAATTTTGCAGAAGAAAATTGAAGAAGAAAAATTAGATATTCCACCAGAAGCGTTATATAACAGTACTAATAATAACAATCATTTTTTACATTTCTATATGCTAATGTGGCAAGATGAGCAAAACTCATTTTGTGGATAATGTTTAAAATTCATACACGCCATACACAAGTTATCAACATGTGTATAACTTCGCCAAATCTATGTTTTTAAGACTTATCCACCAATCCACAGCACCTACTACTATTACTAAGAACTTAAAACCTATATAATTATATATAAACGACTGGAAGGAGTTTTAATTAATGATGGAATTCACTATTAAAAGAGATTATTTTATTACACAATTAAATGACACATTAAAAGCTATTTCACCAAGAACAACATTACCTATATTAACTGGTATCAAAATCGATGCAAAAGAACATGAAGTTATATTAACTGGTTCAGACTCTGAAATTTCAATAGAAATCACTATTCCTAAAACTGTAGATGGCGAAGATATTGTCAATATTTCAGAAACAGGCTCAGTAGTTGGAAATGTGAACTTTATTTCTCGATTATTAGAAGGACATTATCCTGATACAACACGTTTATTCCCTGAAAACTATGAAATTAAATTAAGTATAGACAATGGGGAGTTTTATCATGCGATTGATCGTGCATCTTTATTAGCACGTGAAGGTGGTAATAACGTTATTAAATTAAGTACAGGTGATGACGTTGTTGAATTGTCTTCTACATCACCAGAAATTGGTACTGTAAAAGAAGAAGTTGATGCAAACGATGTTGAAGGTGGTAGCCTGAAAATTTCATTCAACTCTAAATATATGATGGATGCTTTAAAAGCAATCGATAATGATGAGGTTGAAGTTGAATTCTTCGGTACAATGAAACCATTTATTCTAAAACCAAAAGGTGACGACTCGGTAACGCAATTAATTTTACCAATCAGAACTTACTAAAAATAAATATAAATAAAGGATGACGTGATTAATTAAAACGTCATCGTGAAACACGTCGCGGTAAAAAGTTAGAACATCAAGATCGTATAGATATCCCAGAATTACCTGAAGATGCTGGTTCTTTCTTAATCATTCATCAAGGTGAACAATGAAGTTAAATACACTCCAATTAGAAAATTATCGTAACTATGATGAGGTTACGTTGAAATGTCATCCTGACGTGAATATCCTCATTGGAGAAAATGCACAAGGAAAGACAAATTTACTTGAATCAATTTATACCTTAGCTTTAGCAAAAAGTCATAGAACGAGTAATGATAAGGAACTCATACGTTTTAATGCTGATTATGCTAAAATAGAAGGTGAGCTTAGTTATAGACACGGCACGATGCCATTAACAATGTTTATAACTAAAAAAGGTAAACAAGTCAAAGTGAATCACTTAGAGCAAAGTCGTCTAACTCAATATATTGGACACCTCAATGTGGTTCTATTTGCGCCAGAAGATTTGAATATTGTAAAATCTCAAGGACAGCAACGTACAACGGCTTTGTCCATTAAATTAGCTGAAATTGAGTTAATGAATATCGAAGTTGGGGAATATCCCATCTTATTATTAGACGATGTACTCAGTGAATTAGATGATTCGCGTCAAACGCATTTATTAAGTACGATTCAGCATAAAGTACAAACATTTGTCACTACGACATCTGTAGATGGTATTGATCATGAAATCATGAATAACGCTAAATTGTATCGTATTAATCAAGGTGAAATTATAAAGTAACAGAAAGCGATGGTGACTGCATTGTCAGATGTAAACAACACGGATAATTATGGTGCTGGGCAAATACAAGTATTAGAAGGTTTAGAAGCAGTACGTAAAAGACCAGGTATGTATATAGGATCGACTTCAGAGAGAGGTTTGCACCATTTAGTGTGGGAAATTGTCGATAATAGTATCGATGAAGCATTAGCTGGTTATGCAAATCAAATTGAAGATCACTATGAGGGCGGTATTAAATCTTATGTTGAGTTATTGAACGAAAATAAAGAACCTATTCATGATGAGCCGATTTATATTCATCAATCTAAAGATGATATTGAAGTAGAAATTGCGATTCAATATAACTCAGGATATGCCACAAATCTTTTAACTTACGCAAATAACATTCATACGTACGAAGGTGGTACGCATGAAGACGGATTCAAACGTGCATTAACGCGTGTCTTAAATAGTTATGGTTTAAGTAGCAAGATTATGAAAGAAGACAAAGATAGACTTTCTGGTGAAGATACACGTGAAGGTATGACAGCAATTATATCTATCAAACATGGTGATCCTCAATTCGAAGGTCAAACGAAGACAAAATTAGGTAATTCTGAAGTGCGTCAAGTTGTAGATAAATTATTCTCAGAGCACTTTGAACGATTTTTATATGAAAATCCACAAGTCGCACGTACAGTGGTTGAAAAAGGGTATAAACTGACACAAGGTAAACAAAAGTATTATGTATACAATGATAGGGAACTTGATAAACTTAAATCTGAATTGAATCCAACACCAAAATGGTCTATTGCACGATACAAAGGTCTTGGAGAAATGAATGCAGATCAATTATGGGAAACAACAATGAACCCTGAGCACCGCGCTCTTTTACAAGTAAAACTTGAAGATGCGATTGAAGCGGACCAAACATTTGAAATGTTAATGGGTGACGTTGTAGAAAACCGTAGACAATTTATAGAAGATAATGCAGTTTATGCAAACTTAGACTTCTAAGCGCTGTGAACTGAACTTTTGAAGGAGGAACTCTTGATGGCTGAATTACCTCAATCAAGAATAAATGAACGAAATATTACCAGTGAAATGCGTGAATCATTTTTAGATTATGCGATGAGTGTTATCGTTGCTCGTGCATTGCCAGATGTTCGTGACGGTTTAAAACCAGTACATTCAATTGCTGAGTTAATGGAAGATATTGAAGGTCCTGATTTCCCAACTGCTGGACTTATTTTAGGTAAGAGTGGTATTAGACGCGCATATGAAACAGGTCGTGGTTCAATTCAAATGCGTTCTCGTGCAGTTATTGAAGAACGTGGAGGCGGACGTCAACGTATTGTTGTCACTGAAATTCCTTTCCAAGTGAATAAGGCTCGTATGATTGAAAAAATTGCAGAGCTTGTTCGTGACAAGAAAATTGACGGTATTACTGATTTACGTGATGAAACAAGTTTACGTACTGGTGTGCGTGTCGTTATTGATGTGCGTAAGGATGCCAATGCTAGTGTCATTTTAAATAACTTATACAAACAAACACCTCTTCAAACATCATTTGGTGTGAATATGATTGCTCTAGTGAATGGTAGACCGAAGCTGATTAATTTAAAAGAAGCGTTAGTACATTATTTAGAGCATCAAAAGACAGTTGTTATATCTACATATCGTGCTCAAAACCGTGGTGGTCGTGGTGTTCAAGGTATGAATACATTGGAAGAAGATTTTGTCAGTCAATTGGTAACTTTAAGTACACATGACCATGTATTGTTCTTTACTAACAAAGGTCGTGTATACAAACTAAAAGGTTATGAAGTGCCTGAGTTATCAAGACAGTCTAAAGGTATTCCTGTAGTGAATGCTATTGAACTTGAAAATGATGAAATCATTAGTACAATGATTGCTGTTAAAGACCTTGAAAGTGAAGATAACTTCTTAGTGTTTGCAACTAAACGTGGTGTCGTTAAACGTTCAGCATTAAGTAACTTCTCAAGAATAAATAGAAATGGTAAGATTGCGATTTCGTTCAGAGAAGATGATGAGTTAATTGCAGTTCGCTTAACAAGTGGTCAAGAAGATATCTTGATTGGTACATCACATGCATCATTAATTCGATTCCCTGAATCAACATTACGTATCTACATATCGTGCTCAAAACCGTGGTGGTCGTGGTGTTCAAGGTATGAATACATTGGAAGAAGATTTTGTCAGTCAATTGGTAACTTTAAGTACACATGACCATGTATTGTTCTTTACTAACAAAGGTCGTGTATACAAACTAAAAGGTTATGAAGTGCCTGAGTTATCAAGACAGTCTAAAGGTATTCCTGTAGTGAATGCTATTGAACTTGAAAATGATGAAATCATTAGTACAATGATTGCTGTTAAAGACCTTGAAAGTGAAGATAACTTCTTAGTGTTTGCAACTAAACGTGGTGTCGTTAAACGTTCAGCATTAAGTAACTTCTCAAGAATAAATAGAAATGGTAAGATTGCGATTTCGTTCAGAGAAGATGATGAGTTAATTGCAGTTCGCTTAACAAGTGGTCAAGAAGATATCTTGATTGGTACATCACATGCATCATTAATTCGATTCCCTGAATCAACATTACGTGATGAAACACCAGGAAATGCAATTCATACTGAAGTGATTGATTCAGAAGTAAATGATGAAGATGGACGTATTGAAGTAAGACAAGATTTCATGGACCGTGTTGAAGAAGACATACAACAATCATCAGATGATGATGAAGAATAATAAAAAAATAAGACTTCCCTATATGTAGGGGGGTCTTATTTTTATGCTAGAAAGTAATGCTATACTATATTCAATGATTAGTAATGACTAACTTTCTAATTGTTTCATTGCGTAAGGTATTTCATTGATAAGTCTTGATGGTGGCACCACATACATATCTTTTGCAAGATTTTCGCCAATAAAACTATGTGTATATGTGGCACTCATAACCGCTTCTTTTAAGTTATCAAATTGACCAACAAAACTTGTAATCATACCAGCAAGTGTATCGCCCATACCACCAGTCGCCATTGCTGGGCTACCGATTGTCAATTTAAAGTCTTCATCTTTAAAAGCAGATCCACCAATTAATAAAATTTTGCCATAATCACCTTTATGTGAATCTTCTTTACGCTTAGGAATGTTAATAGAATTTAACGTTTCCATAGTGATATAACCTCCCATGTAAAAGCCTTTTCCGAATTTATTCAATTTTAAAAATATATAGTAACTTTTAACAAAATGTATTATAAATTTCTGAATTCATTATTATTTGTCGTTAAATACAATAGAAAATACTATACCTGTATATGCAATTCGTCAATAGATAAATTATTAAATATGCTTACAACAATCTTAATATCCTTTAACGCACTACAATAGTGCTCTGATAATAGGTTATAAATGTACGTAAAACCATTGTTTCAATAAAAATGAAAACGTATACTTCAAGAAGGATGGGTTACTTAATATAAACAAGGGGGTAACATATATGACTTTATATTTAGATGGTGAAACACTAACAATTGAGTATATTAAATCATTTTTACAAAATAGACAACCTTTGAACCTTCAGGCTAAAGAAGGTTTAGCATTGATTAATGGTACGCAAGCTATGACAGCTCAAGGTGTCATTAGTTATATAGAAGCAGAAGATTTAGGTTACCAATCTGAATGGATTGCTGCATTAACGCATCAGTCTCTTAATGGCATTATAGATGCATATCGACATGATGTGCACGCTGTTCGTAATTTTCAAGAACAGATTAATGTGGCAGCGCGTATGCGTGATTGGTTAGAAGGATCAACATTAACGACGCGACAAGCAGAAATACGTGTACAAGATGCATATACATTGCGTTGTATACCACAAATCCATGGCGCGAGTTTTCAAGTATTCAATTATGTTAAACAGCAATTAGAATTTGAAATGAATGCGGCTAATGATAATCCACTTATATTTGAGGAAGCAAATGCAACGTTTGTTATTTCGGGTGGTAACTTCCATGGACAACCTATTGCTTTTGCATCAATTTATCAAACGACTGCATGTCACTAAATCGACATGATTGATGTTTGAAATCGTTACTTGAAAAAGCAAATATAGTTTGCTATATTAAAAATAACTTAATAAGACATTGTTCGTAGGACAAGTAATATATAGTGTTCGATATCAGAGAGCTTGTGGTTAGTGTGAACAAGAATCAACATATATATGAATCTACCTACTTATTTAAAAGAACAATCGGTGATAACCGTTATTTTAGTGAAGTGCAATTTAGGTTTAGTGTATCTTTATAACTTAAATTGTTAAATAGGGTGGCAACGCGTAGACCACGTCCCTTGTAGGGATGTGGTCTTTTTTTATTTTCTAAAAAATAAAGACGTGCGTCATTCCATAATAAATGATAATTATTTGGGAAAGGATGAAGGTTAATGTTAGACATTAGATTATTCAGAAATGAGCCTGACACAGTTAAGAGCAAAATTGAATTACGCGGAGATGATACAAAACATACAACACAACATGGTTATACAGAAATGATGGTACCACAGCTTGTAAACGCAGATACAATGTATGGTACAGGTCAATTACCTAAATTTGAAGAAGATTTATTTAAAGTAGAAAAAGAAGGATTATATACAATTCCAACTGCTGAAGTACCATTAACGAATTTCTATCGTAATGAAATTATTCAACCAGGTGTACTTCCTGAAAAATTCACTGGTCAATCTGCATGTTTCCGTAGTGAAGCAGGATCAGCAGGTAGAGATACAAGAGGATTAATTCGTTTACATCAATTCGATAAAGTGGAAATGGTACGTTTTGAACAACCTGAAGATTCATGGAATGCTTTAGAAGAAATGACAACAAACGCAGAAGCAATTTTAGAAGAGTTAGGTTTACCATACCGTCGTGTTATTTTATGTACAGGTGATATTGGATTTAGTGCAAGCAAAACATATGATTTAGAAGTTTGGTTACACAAAACATACAACACAACATGGTTATACAGAAATGATGGTACCACAGCTTGTAAACGCAGATACAATGTATGGTACAGGTCAATTACCTAAATTTGAAGAAGATTTATTTAAAGTAGAAAAAGAAGGATTATATACAATTCCAACTGCTGAAGTACCATTAACGAATTTCTATCGTAATGAAATTATTCAACCAGGTGTACTTCCTGAAAAATTCACTGGTCAATCTGCATGTTTCCGTAGTGAAGCAGGATCAGCAGGTAGAGATACAAGAGGATTAATTCGTTTACATCAATTCGATAAAGTGGAAATGGTACGTTTTGAACAACCTGAAGATTCATGGAATGCTTTAGAAGAAATGACAACAAACGCAGAAGCAATTTTAGAAGAGTTAGGTTTACCATACCGTCGTGTTATTTTATGTACAGGTGATATTGGATTTAGTGCAAGCAAAACATATGATTTAGAAGTTTGGTTACGATAATTATGATGAACTAAAACAATCTAAAACGTAACAATTTTGAGCATCACTATTATGGGAAATTAAGTGATAAAAAACTGATTTCGTTGATGTAGTATGAGTAATATCGATGCAGTAGGGTAGGGGGGATTATCGAAAGTGTTAGAGACATGAATCAATATCCCAGACTCATCATTAGATATAAAAAATTATAAAATTAGTACTTAAAAACAACTACAAACCCGTAGAAAATATGGAGGTAGTATTAAATAAAATATTGAAAATTCTCAAAACTAAAAAGCTGATATGAAGCCGATTAAAGACTCCGGTATGTCTAACCTCAGACAAACCGGAGTCTAACGTTATTGCTTGTCATATAGAACTATATTAGACTAGGTATATTATTTTTTCGTAATTATATAAATATAAAGTGAAAAAGGAGGTAATTGAGATGACAACACATTTGAGTTTTAGACAAGGCGTGCAAGAGTGTATCCTTTTAGCCATTGCACAATTTGAATCAATTACTAAATCGCGTTTAAGAATTTACATAGTACTCATTATTGCCGTCATAGTAATGATGTTATCGCTAAGTATGTTTATGCCTTCATATCTAGCAATATTAATTGCAGCCACAATTTCAGCAGCGTTAGGAGTGATGATGGAACGATGATAACTCATATGAACATGTTAATACTTATTTTATTGTGTGGAATCGTAACGCTATTAATTCGAATTATACCTTTTATCATGATTTCAAAAGTGCAATTGCCTGATGTCGTGGTTCGATGGCTATCATTTATCCCAATCACACTATTTACGGCACTTGTCATTGACAGCATTATTCAACAGACGCCTCATGGTGAGGGGTATACATTAAACATCCCTTACATTATCGCGCTCATTCCGACGGTTATTTTATCTATAATCACGCGTAGTTTAACTATTACAATTATTAGTGGGATTGTTATCATGGCATGTCGGTTATCATGGACAACCATTAGTTGTAGTTTGTCATGCATTAACTGGCAATCATTTAACATATGGAACAGATGATTATCCGGGGTGGTGGCGAGAAATTATTGATGGGGGATATGTGCCTATTCATGACTATCAATTTTTAACATTTGATGTTATTGGTAGTCCTTTCGGTTCAAGTTCACCTTTAAACGACCCTCATTTTCCTAAAAAATTAACATTAAGAGATATTGTTAGAGCGAATGAACGAGGTATACAAGCGCTTGGTTATGACAAAATTAATATTTTAATAGGGGGAAGTCTTGGAGGTATGCAAGCAATGGAACTACTTTACAATCGACAGTTTGAAGTAGATAAAGCCATTATTCTTGCTGCAACAAGTCGAACATCATCTTATAGTAGAGCTTTCAATGAAATTGCGCGTCAGGCCATTCATCTTGGTGGTAAGGAAGGTCTAAGTATTGCACGCCAATTAAGAGTGGAAATGAATTGTAAATCTAAATCAAGCTTGATTGCTATGTAGTGGGATTAAATAATCATGTTGAAAATGAAAGCACACAAAAGCGATTTAAATGAGTATGTTAATTACTTATAAAACATGAAAGTTATTATTCAATTAAATGAAATAGAAGCATACAATCTATAAATTGTTAATTTCCATTAAAGAGGTTAAAATAATAGCTATAGTTAAAAATATGGGAGTGGCTTATGTGTTTTCAAAAATACAACCTAAAGCAACAATGATTGCAACGATTACGTTGGTATTTGTCGCTTTAGCTTTATATCTAGTGCCTGGTTTAGGACTAATATTTGCATTATTTGCAACCATACCAGGTATCGTTTTATGGAATAAATCAATACAATCTTTCGGGATTAGTGCACTTATTACAGTAATTATAACAACTGTTTTAGGTAATACTTTCGTTTTAAGTGCTATCATATTAGTCTTAATTCTTGTGTTATCATTAGTGATGTATATTCAAGGTTTAAGTGTTATTCATTTCTTTGGTAAAGCGAAAGGTTTGCCGAATGCAGTAACGATTTTACTATTGGTTATCGGTACAATACTGACACCTACGACGCATATTGTAGGACTACTTGGTGTTATCGATTTAAGTTTGAATTTGAAGCGAATCATGAAAAATAATTCTAAAAAGTGAATAGAGGTGGAATAATGAATCGGCAGTCCACTAAGAAAGCTTTACTAATACCATTTGTCATCATGATCATCACAGCAATTGTTTTAATGGGTGTATGGTTTATCTTTAATAGCCTTATAGCATTAATTGCATCTATCGTTCTTGTCGTGATGATTATTGTTAGCATCGTTTTATTCAGACAAGCTTTAATGAAAATGGATAGTTATGTAGATGGTTTGAGTGCTCAAATTTCAACAACAAATAATAAAGCAATCAAACATTTACCAATTGGCTTGAGTCAATTACGTGAAAAAAGTGTTGGTTATCGTGCCCAATTAACATTAAGTATCGGTGTTGGTGAAGGCACTGAAAATTTAATCGACTTAGATGAATTATCACAATCAGGCCTAGACTTAGCATTAGGACGTGGTGGTGACCAAGTTGCAATTAAAAGTATTAATGGTAATGTGCGCTTCTATGGCGGTAAGACTGACCCGATGGAGAAACGTACTCGTGTAAGAGCACGTGTTATCTCACATGCGTTAAAAGACATCCTTGCAGAGGGTGACAAAGTCATTATCATGGGACATAAACGTCCTGACTTAGATGCAATTGGTGCAGCAATCGGTGTGTCTAGATTTGCAATGATGAATAATTTAGAAGCATACATCGTATTAAATGAGACTGACATTGATCCAACATTACGACGCGTGATGAACGAAATTGATAAAAAGCCAGAGTTAAGAGAGCGATTTATTACATCAGATGATGATAAAATTTATCATCCAGTAACAGTTGCACAAGCAGCAGATGAACTGTTAAGTTTAGAAGGTATTGAAGCATCATATGTTGTTGCGAGACGTGAAGATAATCTGATTGGTATATCTGCGCGTTCACTCGGTTCAGTAAATGTCCAGTTAACAATGGAAGCACTTGGTGGCGGTGGACATTTAACCAATGCTGCAACACAACTTAAAGGTGTGACAGTCGAAGAGGCGATAGCGCAATTACAACAAGCAATTACAGAACAATTAAGTAGGAGTGAAGATGCATGAAAGTAATTTTTACACAAGATGTTAAAGGTAAAGGTAAAAAAGGTGAAGTTAAAGAAGTACCAGTAGGTTATGCAAATAACTTCTTATTGAAAAAGAATTATGCTGTAGAAGCAACACCAGGTAACCTGAAACAATTAGAGTTACAGAAAAAACGTGCAAAACAAGAACGCCAACAAGAAATTGAAGATGCTAATTGATGTTGTAACATTGATGGATCAATTATCGACGGAAGGTACGTTGAATGAAGCGGGTGGCCCGCAATATCTTGCAGAGTTATCTACAAATGTACCAACGACGCGAAATGTTCAGTATTATACTGATATCGTTTCTAAGCATGCATTAAAACGTAGATTAATTCAAACTGCAGATAGTATTGCCAATGATGGATATAATGATGAACTTGAACTAGATGCGATTTTAAGTGATGCAGAACGTCGAATTTTAGAGCTATCATCTTCTCGTGAAAGCGATGGCTTTAAAGACATTCGAGACGTCTTAGGACAAGTATATGAAACAGCTGAAGAGCTTGATCAAAATAGTGGTCAAACACCAGGTATTCCTACAGGATATCGAGATTTAGACCAAATGACAGCAGGGTTCAACCGAAATGATTTAATTATCCTTGCAGCGCGTCCATCTGTAGGTAAGACTGCGTTCGCACTTAATATTGCTCGTGAATCTGGTTCGATTGAGCAAGATGCCGATATCGTTGCATTCTTATACCGTGATGATTACTATAACCGTGGTGGCGATGAAGATGATGACGATGATGGTGGTTTCGAGCCGCAAACGAATGATGAAAACGGCGAAATTGAAATCATCATTGCTAAGCAACGTAATGGTCCAACAGGCACAGTTAAGTTACACTTTATGAAACAATATAATAAATTTACAGATATCGATTATGCACATGCTGATATGATGTAAAAAAGTTTTTCCGTACAATAATCATTTTAGTGATAAAATTGTACGGTTTTTATTTTGTTCTGAACGGGTTGATATATGTTAAGTTTGTGTATTGGAAGTGATGAATTAGTGCTGTCAAAGACTCTGTTAAAGGGTTTTGAGGACGTTGAAGACGATTTGTTAAAATGATTTTTCTTTTAAAAAGGCTGAAAATCAATGTTCGATTTTTATTTGCATTATGGTTCAACGTATCGGTATTCGTATGGCAGATTTACTTGAAAAAGAAACATTCGAAAGATTATTAAAATCAAACATTGAATATAAACAAGCATATTTCAAAGGCATGTTTAACGAAACATGCCCATCATTTGATGATATCTTTGAAGAATATTATGCAGCAGGTCAACGTCTAAAAGAATTTGTAACAGACACATCAAAAATCTTAGACGATGCATTTGTAGCAGATGAAAAGGTACTTTTCGAAGGTGCGCAAGGTGTAATGTTAGATATCGACCATGGTACATATCCATTCGTTACATCAAGTAATCCAATTGCAGGTAACGTTACTGTTGGTACAGGTGTAGGTCCTACATTCGTTTCAAAGGTAATTGGTGTATGTAAAGCTTATACATCACGTGTTGGTGATGGTCCATTCCCTACTGAATTATTCGATGAAGATGGACATCATATTAGAGAAGTTGGTCGTGAATACGGTACAACAATCGATTCGATTATTTAGATAAAAAACACTAACGTAAAGGTGGTATTTGCTAGTCATAATTTAGAAGATTAGATGATATTTAATGAAAATTAAGATAAAATACTTGAATGTAGGAAGTCTGATGTCGAAAATGACTATTAAAATAGAGTAGACGTAAGTGTGAATGCAAGTATCTAAAATAGAAAAATTTCAAAAATAGCGTAATTATTATAATAAATAGACTGCCAATAAAATGCAATTTTTCACTTATAACATTCTTCAAAAAATAATAGCAAAATTATGTAAAAAATATCTTGTCATGGCAAGATTGGCTGTGCTATAATCTATCTTGTGCTTAAGAACGGCTCCTTGGTCAAGCGGTTAAGACACCGCCCTTTCACGGCGGTAACACGGGTTCGAGTCCCGTAGGAGTCACCATTTTTTAGGTCTCGTAGTGTAGCGGTTAACACGCCTGCCTGTCACGCAGGAGATCGCGGGTATAATAGGTTACTATACGTTATAAGACGGAAAATGCGCACAATAACAAAAATAGTAAGCGACATCCTGTGATTTTTTACACAAACATAAACGATAAAGAACAAAAAATGATAAAATAATATTAATGATTTAAGAAAAGAGGTTTATGCAAATGGCTAGAAAAGTTGTTGTAGTTGATGATGAAAAACCGATTGCTGATATTTTAGAATTTAACTTAAAAAAAGAAGGATACGATGTGTACTGTGCATACGATGGTAATGATGCAGTCGACTTAATTTATGAAGAAGAACCAGACATCGTATTACTAGATATCATGTTACCTGGTCGTGATGGTATGGAAGTATGTCGTGAAGTGCGCAAAAAATACGAAATGCCAATTATAATGCTTACTGCTAAAGATTCAGAAATTGATAAAGTGCTTGGTTTAGAACTAGGTGCAGATGACTATGTAACGAAACCGTTTAGTACGCGTGAATTAAGGCTGTATTTTACAAATAACCTTGAAAAAGAGCTGCTTGATAATTTTAAGAAGAATATTACGCAGTACGCTAAGCAATTAGAAATTAGTATTGAAAAAGTATATGACGAAAAGGGCTCCGTAAATGCACAAAAAGATATTCAAAATTTATTAAGTGAGTATGCCAACCGTCAAGAAATTGGAGAAATTCGTTTTATAGATAAAGACCAAATTATTATTGCGACGACGAAGCAGTCTAACCGTAGTCTAATCAATCAAAAAGCGAATGATAGTTCTGTCCAAAAAGCACTATCACTAGGACAATCAAACGATCATTTAATTTTAAAAGATTATGGCGGTGGTAAGGACCGTGTCTGGGTATATAATATCCCCGTTAAAGTCGATAAAAAGGTAATTGGTAATATTTATATCGAATCAAAAATTAATGACGTTTATAACCAATTAAATAATATAAATCAAATATTCATTGTTGGTACAGCTACGATTGTGCAGGAAACAGGATTTGTAACGGGTTATATCGCTGTGTTACATGACGTGACTGAACAACAACAAGTTGAACGTGAGCGTCGTGAATTTGTTGCCAATGTATCACATGAGTTACGTACACCTTTAACTTCTATGAATAGTTACATTGAAGCACTTGAAGAAGGTGCATGGAAAGATGAGGAACTTGCGCCACAATTTTTATCTGTTACCCGTGAAGAAACAGAACGAATGATTCGACTGGTCAATGACTTGCTACAGTTATCTAAAATGGATAATGAGTCTGATCAAATCAATAAAGAAATTATCGACTTTAACATGTTCATTAATAAAATTATTAATCGACATGAAATGTCTACGAAAGATACAACATTTATTCGAGATATTCCGAAAAAGACGATTTTCACAGAATTTGATCCTGATAAAATGACGCAAGTATTTGATAATGTCATTACAAATGCGATGAAATATTCTTACGATTGTGCAGGAAACAGGATTTGTAACGGGTTATATCGCTGTGTTACATGACGTGACTGAACAACAACAAGTTGAACGTGAGCGTCGTGAATTTGTTGCCAATGTATCACATGAGTTACGTACACCTTTAACTTCTATGAATAGTTACATTGAAGCACTTGAAGAAGGTGCATGGAAAGATGAGGAACTTGCGCCACAATTTTTATCTGTTACCCGTGAAGAAACAGAACGAATGATTCGACTGGTCAATGACTTGCTACAGTTATCTAAAATGGATAATGAGTCTGATCAAATCAATAAAGAAATTATCGACTTTAACATGTTCATTAATAAAATTATTAATCGACATGAAATGTCTACGAAAGATACAACATTTATTCGAGATATTCCGAAAAAGACGATTTTCACAGAATTTGATCCTGATAAAATGACGCAAGTATTTGATAATGTCATTACAAATGCGATGAAATATTCTTACAACTATTACGCCATTTCAGATTATTCATTCGAAAAATGATCATCCAGAAGGTACGATTGCGACGGTATCTAATGTAAATAAGCTGACGAAACCTTTAAAAAATAAAGAAGTGAAGTCCGTGGAACATGTTCGTCGTGATCATAACTTGATGATTCCTGATTTGAGCAGTGATTTTACATTATTCGATTTTACGTATGATTTACCGTTATCAACATATCTTGGCCAAGTACTGAACATGAATGCGAAAGTACCAAATCATTTCAATTTCAATCGTTTGGTCATAGATCATGATGCTGATGATAATATCGTGCTTTATGCTATAAGCAAAGATCGCCACGATTACGTAAAATTAACAACTACAACGAAAAATGATCATTTTTTAGATGCATTAGCAACAGTGAAAAAAGATATGCAACCATACACAGATATCATCACAAACAAAGATACAATTGATCGTACGACGCATGTTTTTGCATTGCCGAAATTAGAGTCTGTACGTTCAAGCTTAGCGAACAATAGTGATATTAATTTTGAAAAAGTAACAAACATCGCTATCGGTTACGAAATGCAAGATAATCCGGATCATAATCACATTGAAGTGCAGATTAACAGTGAACTCGTACCGCGTTGGTATGTAGAATATGATGGCGAATGGTATGTTTATAACGATGGGAGGCTTGAATAAATGAACTGGAAACTGACGAAGACACTTTTCATTTTCGTGTTTATTCTTGTCAACATCGTATTAGTATCGATTTATGTTAATAAAGTCAATCGCTCACACATTAATGAAGTTGAGAGTAACAATGAAGTTAATTTTCAACAAGAAGAAATCAAAGTACCGGCTAGTATTTTAAATAAATCAGTTAAAGGCATACAATTAGAACAAATTACGGGGCGTTCAAAAGACTTTAGTTCTAAAGCTAAGGGCGATTCGGATTTGACCACATCAGACTATGTTGAAGCGACAAATAATAGCCCTAAAATTATTAATCATTAATATGAATCGTAATAAGCTAGCATTGCAAGCTCATCATATGTGAGAAGCGGTGCTAGCTTTTTGCTGGTATGGTTTATTATGGCTGACGTTTTTGCGTCCTAACATGCGCATTTATTCATATATTAAGTAGAACCGCATTGTAAAATTAACGTAACTGCTATTTTAAAAACTTTAGTATTTGTCTAATCATTGTTATAATAATTAGGACATTCATTGCACGTGATTATCAAAATTTAATTATAAGAGACCGGTCGATGAACTAAAGTTACAGAATAGGAAAGGTATACAAAACAGCTAATATACTGATAGTTTCTGTAGGGAAAATCGTATATTTGCACTGATGTATATTGCAGTCATATAGAGAGATTGACTGCTTAAATAGAAAGGATGAGCCGCTTGATACGCATGAGTGTATTAGCAAGTGGTAGTACCGATATGTTGAGAATGTGTCGTTATCCATGGAAGACGAAACAACGTATTTTAGGCGATATGGGTCATGTATCTAATGAGGATGCGGGTCATGCGATGACAGACGTGATTACAGGTAACACGAAACGTATTTACCTATCGCATTTATCACAAGATAATAACATGAAAGATTTGGCGCGTATGAGTGTTGGCCAAGTATTGAACGAACACGATATTGATACGGAAAAAGAAGTATTGCTATGTGATACGGATAAAGCTATTCCAACGCCAATATATACAATATAAATGAGAGTCACCCGATAAAGTTCCGCACTGCTGTGAAACGACTTTATCGGGTGTTTTTTTATGTTGTTGGTGGGAAATGGCTGTTGTTGAGATTAAGGTTCTAGTTGAAACGCAAAAAATAATTCGATATTAAATGTAATTTATAAATAATTTACATAAAATCAATCATTTTAATATAAGGATTATGATAATATAACATAAAATATTACATACAAATGATATCCATGGCCGACTAGCCGAAGAAAAAGGGCGTGTCATCGGTATGGCTAAATTAAAAACAGTAAAAGAACAAGAAAAGCCTGATTTAATGTTAGACGCAGGAGACGCCTTCCAAGGTTTACCACTTTCAAACCAGTCTAAAGGTGAAGAAATGGCTAAAGCGATGAATGCAGTAGGTTATGATGCTATGGCAGTCGGTAACCACGAATTTGACTTTGGATACGACCAGTTGAAAAAGTTAGAGGGTATGTTAGACTTCCCGATGTTAAGTACTAACGTTTATAAAGATGGAAAACGCGCATTTAAACCTTCAACGATTGTAACGAAAAATGGTATTCGTTATGGAATTATTGGCGTAACGACACCAGAAACAAAGACGAAAACAAGGCCTGAAGGCATTAAAGGTGTTGAATTTAGAGATCCATTACAAAGTGTGACAGCAGAAATGATGCGTACATAAAATATTACATACAAATGATATCCATGGCCGACTAGCCGAAGAAAAAGGGCGTGTCATCGGTATGGCTAAATTAAAAACAGTAAAAGAACAAGAAAAGCCTGATTTAATGTTAGACGCAGGAGACGCCTTCCAAGGTTTACCACTTTCAAACCAGTCTAAAGGTGAAGAAATGGCTAAAGCGATGAATGCAGTAGGTTATGATGCTATGGCAGTCGGTAACCACGAATTTGACTTTGGATACGACCAGTTGAAAAAGTTAGAGGGTATGTTAGACTTCCCGATGTTAAGTACTAACGTTTATAAAGATGGAAAACGCGCATTTAAACCTTCAACGATTGTAACGAAAAATGGTATTCGTTATGGAATTATTGGCGTAACGACACCAGAAACAAAGACGAAAACAAGGCCTGAAGGCATTAAAGGTGTTGAATTTAGAGATCCATTACAAAGTGTGACAGCAGAAATGATGCGTGAAGCATATGGCGTTAAGAATTTCTCTAAAAAGACTGACTTTGCCGTGACAAATGGTGGAGGTATTCGTGCCTCTATCGCAAAAGGTAAGGTGACACGCTATGATTTAATTTCAGTATTACCATTTGGAAATACGATTGCGCAAATTGATGTAAAAGGTTCAGACGTCTGGACGGCTTTTGAACATAGTTTAGGCGCACCAACAACACAAAAAGATGGTAAGACAGTATTAACAGCGAATGGCGGTTTACTACATATCTCTGATTCAATCCGTGTTTACTATGATATGAATAAACCGTCTGGCAAACGAATTAATGCTATTCAAATTTTAAATAAAGAGACAGGTAAGTTTGAAAATATTGATTTAAAACGTGTATATCACGTAACGATGAATGACTTCACAGCATCAGGTGGCGACGGATATAGTATGTTCGGTGGCCCTAGAGAAGAAGGTATTTCATTAGATCAAGTACTAGCAATCTTAAACAAGAGGTACGGTAGTGTTTTTTTATGAAAAAAAGCTATAACCGTTGATAAATATGGGATATAAAAACGGGGATAAGTAATAAGACATCAAGGTATTTATCCACAGAAATGGGGATAGTTATCCAGAATTGTGTACAATTTAAAGAGAAATACCCACAATGCCCACAGAGTTATCCACAAATACACAGGTTATACACTAAAAATTGGGCATGAATGTCAGAAAAATATCAAAAACTGCAAAGAATATTGGTATAATAAGAGGGAACAGTGTGAACAAGTTAATAACTTGTGGATAACTGGAAAGTTGATAACAATTTGGAGGACCAAACGACATGAAAATCACCATTTTAGCTGTAGGGAAACTAAAAGAGAAATATTGGAAGCAAGCCATAGCAGAATATGAAAAACGTTTAGGCCCATACACCAAGATAGACATCATAGAAGTTCCAGACGAAAAAGCACCAGAAAATACCGCAGTCTTTCATTTCAAGTAAATAATAGCGAAATATTCTTTATACTGAATACTTATAGTGAAGCAAAGTTCTAGCTTTGAGAAAATTCTTTCTGCAACTAAATATAGTAAATTACGGTAAAATATAAATAAGTACATATTGAAGAAAATGAGACATAATATATTTTATAATAGGAGGGAATTTCAAATGATAGACAACTTTATGCAGGTCCTTAAATTAATTAAAGAGAAACGTACCAATAATGTAGTTAAAAAATCTGATTGGGATAAAGGTGATCTATATAAAACTTTAGTCCATGATAAGTTACCCAAGCAGTTAAAAGTGCATATAAAAGAAGATAAATATTCAGTTGTAGGGAAGGTTGCTACTGGGAACTATAGTAAAGTTCCTTGGATTTCAATATATGATGAGAATATAACAAAAGAAACAAAGGATGGATATTATTTGGTATATCTTTTTCATCCGGAAGGAGAAGGAAAGACTACTAAAAATGATTCAGAAATTGAAAAATCAAATAAAGAGAATAAATTAACCGGTAAAGTTGGAGAAAAATTAGCGCTAAATTACTTTAATGAGCTAATTGATAATAAAATAGACGAAGATAAGAAAGAACAGTTTAGGAATATTTTAAATGATAATCCAGGCTCTCAACACGGTCATGGCTATGATTTAGTAGCTTTTGATCCAACAAATACAGATAAAGCTGTAGAAAAATTTATTGAAATTAAAACATCTACATCTTCTAGTATTGAGGAACCATTTTTTATGTCGCTAAATGAAATGTTTGCTATGAAAGAATATAAGCAGAAATATTTAATATTAAGAATATTTAATGTTTCCGGTAAAGAACCACAATTTTATTTTATAGATCCATATGCAAATTATTCTGAATTTAAAGATGTAGATGATCTCATTGACAAAGTATTTAATGTAGAAGCTATTCAGTATAAAGTTATAATCTATGGTAGTGAAATCAAACGGGAGAAATTAGAGAATTTATTTAATCAATTTGCTATAAAAAATGTTGAAAAGAACATTGTCTATGATGAACTGAAATCTTTAGATATTACAATCATTGAGTCACAGGATTCATATAAAAATAAATTGAAGAGATTATTTTCGGTTCTGTTGCAAAGTAAAAAAATATAGCTAACCACTAATTTATCATGTCAGTGTTCGCTTAACTTGCTAGCATGATGCTAATTTCGTGGCATGGCGAAAATCCGTAGATCTGAAGAGACCTGCGGTTCTTTTTATATAGAGCGTAAATACATTCAATACCTTTTAAAGTATTCTTTGCTGTATTGATACTTTGATACCTTGTCTTTCTTACTTTAATATGACGGTGATCTTGCTCAATGAGGTTATTCAGATATTTCGATGTACAATGACAGTCAGGTTTAAGTTTAAAAGCTTTAATTACTTTAGCCATGAACCATCTAATCTTCAACAAACTGGCCCGTTTGTTGAACTACTCTTTAATAAAATAATTTTTCCGTTCCCAATTCCACATTGCAATAATAGAAAATCCATCTTCATCGGCTTTTTCGTCATCATCTGTATGAATCAAATCGCCTTCTTCTGTGTCATCAAGGTTTAATTTTTTATGTATTTCTTTTAACAAACCACCATAGGAGATTAACCTTTTACGGTGTAAACCTTCCTCCAAATCAGACAAACGTTACAAATTCTTTTCTTCATCATCGGTCATAAAATCCGTATCCTTTACAGGATATTTTGCAGTTTCGTCAATTGCCGATTGTATATCCGATTTATATTTATTTTTCGGTCGAATCATTTGAACTTTTACATTTGGATCATAGTCTAATTTCATTGCCTTTTTCCAAAATTGAATCCATTGTTTTTGATTCACGTAGTTTTCTGTATTCTTAAAATAAGTTGGTTCCACATTTCCACTTTTTGTCTTGTCCACTAAAACCCTTGATTTTTCATCTGAATAAATGCTACTATTAGGACACATAATATTAAAAGAAACCCCCATCTATTTAGTTATTTGTTTAGTCACTTATAACTTTAACAGATGGGGTTTTTCTGTGCAACCAATTTTAAGGGTTTTCAATACTTTAAAACACATACATACCAACACTTCAACGCACCTTTCAGCAACTAAAATAAAAATGACGTTATTTCTATATGTATCAAGATAAGAAAGAACAAGTTCAAAACCATCAAAAAAAGACACCTTTTCAGGTGCTTTTTTTATTTTATAAACTCATTCCCTGATCTCGACTTCGTTCTTTTTTTACCTCTCGGTTATGAGTTAGTTCAAATTCGTTCTTTTTAGGTTCTAAATCGTGTTTTTCTTGGAATTGTGCTGTTTTATCCTTTACCTTGTCTACAAACCCCTTAAAAACGTTTTTAAAGGCTACTGCTAAATTTTTTTCTAGAAAATCAATCTCTTTTTCCAAAGTTTGTTTTTTAAATTTAGCTGTCTCAATATGTTTACGGTCAGAGCCACGTTCACCACGCTTCAACTCAAAACCCTGTTTTTTCATATGCTCGGGGAATTTATCTTGTAGCCATAACAGTTCTTGACGATTAAACACATTTTTTCCTTGCAGTTTTCCATCACGCATAGGCACAACACCTAAATGCATGTGAGGGGTTTGCTCATCATTATGAACTGTTGCATAAGCAATATTTTGCTTGCCATATCGTTCGGAAAATAATTTATAACTTTCCTCAAAAAATCGTTTTTGTTCTCCTGGATCCAGTTGCTCAAAAAAATCTCGGTCAGATGTTACTAGCAACTCATTTACAAGAACAGCATCTTTCCTCGTTTTTCTTGTACCTGTTTTTTGTGATTCAATAATTTCTTTGACACGTTCGTTGTAATCAATATTTTATTTTGTCCGTTTTGTCTAGCTTACCGAAAGCCAGACTCAGCAAGAATAAAATTTTTATTGTCTTTCGGTTTTCTAGTGTAACGGACAAAACCACTCAAAATAAAAAAGATACAAGAGAGGTCTCTCGTATCTTTTATTCAGCAATCGCGCCCGATTGCTGAACAGATTAATAATAGATTTTAGCTTTTTATTTGTTGAAAAAAGCTAATCAAATTGTTGTCGGGATCAATTACTGCAAAGTCTCGTTCATCCCACCACTGATCTTTTAATGATGTATTGGGGTGCAAAATGCCCAAAGGCTTAATATGTTGATATAATTCATCAATTCCCTCTACTTCAATGCGGCAACTAGCAGTACCAGCAATAAACGACTCCGCACCTGTACAAACCGGTGAATCATTACTACGAGAGCGCCAGCCTTCATCACTTGCCTCCCATAGATGAATCCGAACCTCATTACACATTAGAACTGCGAATATTTTGTCCGTTTTGTCTAGCTTACCGAAAGCCAGACTCAGCAAGAATAAAATTTTTATTGTCTTTCGGTTTTCTAGTGTAACGGACAAAACCACTCAAAATAAAAAAGATACAAGAGAGGTCTCTCGTATCTTTTATTCAGCAATCGCGCCCGATTGCTGAACAGATTAATAATAGATTTTAGCTTTTTATTTGTTGAAAAAAGCTAATCAAATTGTTGTCGGGATCAATTACTGCAAAGTCTCGTTCATCCCACCACTGATCTTTTAATGATGTATTGGGGTGCAAAATGCCCAAAGGCTTAATATGTTGATATAATTCATCAATTCCCTCTACTTCAATGCGGCAACTAGCAGTACCAGCAATAAACGACTCCGCACCTGTACAAACCGGTGAATCATTACTACGAGAGCGCCAGCCTTCATCACTTGCCTCCCATAGATGAATCCGAACCTCATTACACATTAGAACTGCGAATCCTGAAGGAAGATCTGATTGCTTAACTGCTTCAGTTAAGACCGAAGCGCTCGTCGTATAACAGATGCGATGATGCAGACCAATCAACATGGCACCTGCCATTGCTACCTGTACAGTCAAGGATGGTAGAAATGTTGTCGGTCCTTGCACACGAATATTACGCCATTTGCCTGCATATTCAAACAGCTCTTCTACGATAAGGGCACAAATCGCATCGTGGAACGTTTGGGCTTCTACCGATTTAGCAGTTTGATACACTTTCTCTAAGTATCCACCTGAATCATAAATCGGCAAAATAGAGAAAAATTGACCATGTGTAAGCGGCCAATCTGATTCCACCTGAGATGCATAATCTAGTAGAATCTCTTCGCTATCAAAATTCACTTCCACCTTCCACTCACCGGTTGTCCATTCATGGCTGAACTCTGCTTCCTCTGTTGACATGACACACATCATCTCAATATCCGAATAGGGCCCATTTGTCTTTCTTACTTTAATATGACGGTGATCTTGCTCAATGAGGTTATTCAGATATTTCGATGTACAATGACAGTCAGGTTTAAGTTTAAAAGCTTTAATTACTTTAGCCATTGCTACCTTCGTTGAAGGTGCCTGATCTGTAATTACCTTTTGAGGTTTACCAAATTGTTTAATGAGACGTTTGATAAACGCATATGCTGAATGATTATCTCGTTGCTTACGCAACCAAATATCTAATGTATGTCCCTCTGCATCAATGGCACGATATAAATAGCTCCATTTTCCTTTTATTTTGATGTACGTCTCATCAATACGCCATTTGTAATAAGCTTTTTTATGCTTTTTCTTCCAAATTTGATACAAAATTGGGGCATATTCTTGAACCCAACGGTAGACCGTTGAATGATGAACGTTTACACCACGTTCCCTTAATATTTCAGATATATCACGATAACTCAATGTATATCTTAGATAGTAAGAAATAAACTAGTGGCCGATTGTGCTTGATGAGCTTGGGACATAAATCCTAACTCGAAATAAATAAGCATATCACTAAACTGATTTTTTAAAGTTTACAGTGATATGCTTATTTTTTTATCTTACGATTTTGTACGTGCATGCTTGCCTAGGGGTATGGCTCGAGCCATTAGTCTCTCGCACATACTATTCCCTCAGGCGTCAGCACTTACAAAATCGGTTGTAATTTTCATTTTTATACGCATTCTTACTGAGATTATACTAATAAGAGGAATAGTAAAAGCAATTCTAAGTAAAATTGCAGATAAGAGGTAAGTTAAAAGCAGTTCTAAGTAAAATTGCAGATAAGAGGTTTGTTAAAAGCAGTTCTAAGTAAAATTGCAGATAAGAGGTTTGTTAAAAGCAGTTCTCAGTAAAATTACAGATAAGAGGTACGTTAAAAGCAGTTCTAAGTAAAATTGCAGATAAGAGGTAAGTTAATAACTGAATTGAATTATGATGAAATTAAAGATGCTTCTGCAGGATCTTGGTTTGGTGAAAAATTCAAAGATGAACATTTGCCAACTTTCGATGATGTAGTAAAAATAGCAAATGAATATAATATGAATTTAAATGTAGAATTAAAAGGTATTACTGGACCGAATGGACTAGCACTTTCTAAAAGTATGGTTAAGCAAGTGGAAGAACAATTAACAAACTTAAATCAGAATCAAGAAGTGCTCATTTCAAGCTTTAATGTTGTGCTTGTTAAACTTGCAGAAGAAATCATGCCACAATATAACAGAGCAGTTATATTCCATACAACTTCGTTTCGTGAAGACTGGAGAACACTTTTAGATTACTGTAATGCTAAAATAGTAAACACTGAAGATGCCAAACTTACTAAAGCAAAAGTAAAAATGGTAAAAGAAGCGGGTTATGAATTGAACGTATGGACTGTAAACAAACCAGCACGTGCTGAAATTACAAATAAGAAATCCATAAAAAAAGAAAATGGACTCGTTACAGTGTCACTTTCAACATACAATGAAAATGAAGAAATTGTATTTAAGGGAGAAGTAACAGCACTTATTAATAATTCATAATAAAACAGTGAAGCAACCATCGTTACGGATTGCTTCACTGTTTTGTTATTCATCTATATCGTATTTTTTATTACCGTTCTCATATAGCTCATCATACACTTTACCTGAGATTTTGGCATTGTAGCTAGCCATTCCTTTATCTTGTACATCTTTAACATTAATAGCCATCATCATGTTTGGATTATCTTTATCATATGATATAAACCACCCAATTTGTCTGCCAGTTTCTCCTTGTTTCATTTTGAGTTCTGCAGTACCGGATTTGCCAATTAAGTTTGCATAAGATCTATAAATATCTTCTTTATGTGTTTTATTTACGACTTGTTGCATACCATCAGTTAATAGATTGGCTGAAATTACAAATAAGAAATCCATAAAAAAAGAAAATGGACTCGTTACAGTGTCACTTTCAACATACAATGAAAATGAAGAAATTGTATTTAAGGGAGAAGTAACAGCACTTATTAATAATTCATAATAAAACAGTGAAGCAACCATCGTTACGGATTGCTTCACTGTTTTGTTATTCATCTATATCGTATTTTTTATTACCGTTCTCATATAGCTCATCATACACTTTACCTGAGATTTTGGCATTGTAGCTAGCCATTCCTTTATCTTGTACATCTTTAACATTAATAGCCATCATCATGTTTGGATTATCTTTATCATATGATATAAACCACCCAATTTGTCTGCCAGTTTCTCCTTGTTTCATTTTGAGTTCTGCAGTACCGGATTTGCCAATTAAGTTTGCATAAGATCTATAAATATCTTCTTTATGTGTTTTATTTACGACTTGTTGCATACCATCAGTTAATAGATTGGCTGTTAATATTTTTTGAGTTGAACCTGGTGAAGTTGTAATCTGGAACTTGTTGAGCAGAGGTTCTTTTTTATCTTCGGTTAATTTATTATATTCTTCGTTACTCATGCCATACATAAATGGATAGACGTCATATGAAGGTGTGCTTACAAGTGCTAATAATTCACCTGTTTGAGGGTGGATAGCAGTACCTGAGCCATAATCATTTTTCATGTTGTTATAAATACTCTTTTGAACTTTAGCATCAATAGTTAGTTGAATATCTTTGCCATCTTTTTTCTTTTTCTCTATTAATGTATGTGCGATTGTATTGCTATTATCGTCAACGATTGTGACACGATAGCCATCTTCATGTTGGAGCTTTTTATCGTAAAGTTTTTCGAGTCCCTTTTTACCAATAACTGCATCATCTTTATAGCCTTTATATTCTTTTTGTTTTAATTCTTCAGAGTTAATGGGACCAACATAACCTAATAGATTTTTATTTTTAGATACTTTTTTTATTTTACGATCCTGAATGTTTATATCTTTAACGCCTAAACTATTATATATTTTTATCGGACGTTCAGTCATTTCTACTTCACCATTATCGCTTTTAGAAATATAACTGCTATCTTTATAAACTTGTTTGAAATTTTTATCTTCAATTGCATCAATAGTATTATTAATTTCTTTATCTTTTGAAGCATAAAAATATATACCAAACCCGACAACTACAACTATTAAAATAAGTGGAACAATTTTTATCTTTTTCATCAATATCCTCCTTATATAAGACTACATTTGTAGTATATTACAAATGTAGTATTTATGTCAAAATAATGTTATAATTTTTGTGATATGGAGGTGTAGAAGGTGTTATCATCTTTTTTAATGTTAAGTATAATCAGTTCATTGCTCACGATATGTGTAATTTTTTTAGTGAGAATGCTCTATATAAAATATACTCAAAATATTATGAATGACAAAGAAATTGAATATATTATTCTACATGAACTATCACATGTGAAAAGTCATGACTTAATATTCAACCAGCTTTATGTTGTTTTTAAAATGATATTCTGGTTTAATCCTGCACTATATATAAGTAAAACAATGATGGACAATGACTGTGAAAAAGTATGTGATAGAAACGTTTTAAAAATTTTGAATCGCCATGAACATATACGTTATGGTGAATCGATATTAAAATGCTCTATTTTAAAATCTCAGCACATAAATAATGTGGCAGCACAATATTTACTAGGTTTTAATTCAAATATTAAAGAACGTGTTAAGTATATTGCACTTTATGATTCAATGCCTAAACCTAATCGAAACAAGCGTATTGTTGCGTATATTGTATGTAGTATATCGCTTTTAATACAAGCACCGTTACTATCTGCACATGTTCAACAAGACAAATATGAAACAAATGTATCATATAAAAAATTAAAAGTTGAAAATAGTATGACTTTGAAACAAAAAGATACTTATAAATATGTAGGTAAAACTGGAACAGGAATCGTGAATCACAAAGAAGCAAATGGATGGTTCGTAGGTTATGTTGAAACGAAAGATAATACGTATTATTTTGCTACACATTTAAAAGGCGAAGACAATGCGAATGGCGAAAAAGCACAACAAATTTCTGAGCGTATTTTAAAAGAAATGGAGTTAATATAATGGATAATAAAACGTATGAAATATCATCTGCAGAATGGGAAGTTATGAATATCATTTGGATGAAAAAATATGCAAGTGCGAATAATATAATAGAAGAAATACAAATGCAAAAGGACTGGAGTCCAAAAACCATTCGTACACTTATAACGAGATTGTATAAAAAGGGATTTATAGATCGTAAAAAAGACAATAAAATTTTTCAATATTACTCTCTTGTAGAAGAAAGTGATATAAAATATAAAACATCTATAACCTAAGTGAGGTTTTAAGTTGTTCTAAGGTTTAATTTAATTTATGTTAAAATAGTTGGTATAAAAATACATGATAAACTATAAACTAAATTCAAAATAACTTATGGGGTAGGCAATTATGGAAAATAAAATATAAATGATAATGAAAAAAGAGTGCTAAGGGAAATTTATAACCATCATAATATTTCGCGTACTCAAATATCTAAAAATCTTGAGATTAATAAGGCAACGATTTCTAGTATTTTGAATAAGTTAAAGTATAAATCTCTTGTTAATGAGGTTGGTGAGGGTGATAGCACGAAGAGTGGTGGTAGAAAACCTATTCTTCTGAAGGTTAATCATCTTTATGGTTATTTTATTTCTTTGGATTTAACTTATAGTTCTGTTGAAGTGATGTACAATTATTTTGATGGTAATGTCATTAAGCATGAATCTTATGATTTACCTGATGAAAAGGTTAGTAGTATATTAAGCATAATTCAATTTTATAATGAAAAAAATCCAGTCGTAGTTGAAGAAATGGAACAATTTATAAATAAAATTGCTGTTTTAATACATAATTTAAACACCCAGTTTAATCCGAATGCAATTTACATTAACTGTCCATTGTTCAATGAAATGCCTGAAATATTAGAAGCAATTAAGAACCAGTTCAAACAATATTCACGTAACGAAATTCAAATAAAGTTAACATCTAATGTCAAATTTGCAACTTTGCTAGGTGGTACATTAGCAATTATCCAAAAAGTACTACAGATTAATGATATTTACTTAGATATAAAAGCATAAAAAACTAATTCAAATGAATAATCAAAGTTCGTAATTGTCTTTATAAAAAAATCCCTCAATCCGAATTGAATTTTCGGATTGAGGGATTTTTATAGTTCTATTGCAGAAGAAAACTATTTTAAAAATGCTGGTAAATGTTGATAGCCACCTCTAACGTTAACAATGCTTGAACTAGGGTAAACATTATATGGTTGGTACATTTGCATACCAAATTGATTTATTTTTTTCATTTGTGAAAAATGGTGTGGTGGAGCTGGCTGATTGAGTGTTAAAGTTTCGATAAATGAAGTTTCATCTTTAACATTAAAAGCCCAGTTGTTTATTTTCTCATAACCCAAAGTAGTTGTAGGTAATGAACCTAGCGCTTTACCACAAGGACTCCCTGCACCATGACCTGGCCAAATTTGAATATAGTCTGGTAATGTTGCAGCAAATTGTATGGACTGATACATTTGTTTTGCTCCGATTTTTGTAGAACCTTCAACATTTACAGCTTTTTCTAATAGATCTGGTCTACCTACATCACCAACAAAGATGAAGTCACCGCTAAATAATCCCATTGGTATACTGGAACCCCCACCTTCGTCAGTAAGTAAAAAACTAATACTCTCAGGGGGATGGCCTGGAGTGTGTAAGACTTCTTACTCATGGTACAAGCAATTAACTTTATATCTTGATCGATTGCTTGATCGATAAGTGAGTATAAAGAATCAACATTTTTCTTGTTCATTACATAACGCATCATAATATTACCTAGTCCAAACATATTCATTTTTGATAATGGCATATGTATTGGATCCTTAGGTAACATAAGGTCAAACATTTTGGAAATACCTTTCTTTTTAACGCGAGTTGATTGCGCTTTTTTTAATGCGTTGAGGCCCCAAAAAGTAAAGAAAATAGTTACATCTTTACCTGCTGCTTTAGCGCCATTTGCGATGATCATTGCTGCTACTGCCTTATCTAACTCACCGCTAAATAAAACAATTGTTGTACCTGTAGCAGTGTCATTGATTTCAAATTCTTTTGGCTTTTCTTTTTGAATAATTGCATTAATTACATTTGCTTCTTCAGTAAGATTTACAAGGGTATTCCCTGTTTGTTTCGCCCAACTTTTAATCATACTTACCTCCTATAAATACCTATGAGGGTATAATAAAACGGATAGAATCATTTGCCAAATACCTATAGGGGTATTTGACAATTTTGTTTTAATTTATTATTATTAACTTAATCAATTTATGTGGAGGAAATGAATATGACTTATGATAAAAAAATGATTAATCGTATAAATAGAATACAAGGTCAATTAAATGGTGTCGTAAAAATGATGGAAGAAGAAAAAGATTGCAAAGATATAATTACGCAACTTAGTGCATCTAAAGGTTCTATACAACGTTTAATGGGGATTATAATTAGTGAAAATTTAATAGAATGCGTTAAAACAGCAGAAGAAAATAATGAAAGTTCTCAAGAATTAATTAATGAAGCAGTTAATTTATTAGTTAAAAGTAAATAATGGATATAGCAAATATGACTATTATGTTGCTAATTGGCGTACTGGGTGGATTTATATCTGGATTAATAGGTATTGGGGGTGCTTTTATATCTTCAGTAGGGGCATTTTTTATAAAATTAATGCAAGGATATATACCAGTAGAAAGTGCAATTTTTTTGATAATTGAATGATGATCATTTTCTGAAAATATTATGTGGTCATATAATATAATGCCCATCATTTCACTAATCTCTTTTATTCTCTGAGTTATTTTGATATCTCCTGGAGAAGGTGTGATGTCTTATCAAGAGTAAATTACAAAAGAATCATTTAAATCAATACTTTCACTTTGAATACATGTATTTGAAGTGGAAGGTACTTATTTCAAAAATAGTAAAACCTGTATCTTAAATTACTTAATAGTAACATAAGATACAGGCTGATTTTTTATTCATTGTTATTTATACTAAAGCACCCGATAGCTCTGAAAACAATCACAAATTCAACTTTTCAAAGCCACAGCTTTAAGTTATTTTGTCCAGACAACCCCCATTGCCCAACCCATTTTATGGAATTGGCCCGAGCCACATCCGATATCTAATGCTCTGCCTTTCTTTGGAGACATATTAGACACAAAGAATGAATAATCATTCAAAAGCTCATTCACGAAATCGTAATCTTCTGCAACCTTATCAAACTGTGATTCTATTGTATTCAAAAAGATCCCCCATTCCTACTTTATCGACATTCTTTCATTACTTACCACTTTAGATGTTTTTTCGTTGGGGATAAAACTTCCCTTTAGACAATTTTATCCAAAGACAATACAACAGTGCAACTTTATTAAAGTCACTGTCCTTTATCGCAGCCTTTACTTTTTAGTAAAGACAGTGGCTTCTCTTATCAAGTTTCAAAACATATTATTTTGAAGAAAACGTCCATCTGAAGTGTCAAGTGCAAAATTACATATAAAGGTTTATTCTAAAATGAAAAGATGATACAATCATATTCAGTTACATAAGGAGGTTTCAATTATGTGCACCAGTATCGCAGTAGATAAACTATAAGATATATGGTAATATTCCTTATAACATCAGTACGGATATTGTCAAAAGAATTACCTTTGAAAGTCAGGCTAAATATAGCTATCTTATCGTTGAGAAGGGATTTGCGAAAAGATTGCAAAATCTGCAACGAGCTTTGGGTTTACTATTAATGGTGGAGATGGATATAAAAATGCTCAAAAAAGTACCACCACTATATTTTCATCCTAAGCCAAGTGTAGACTCTGTATTGATTGTTCTTGAACGACATCAACCATTGATTTCAAAGAAGGACTACAAAAAGTATCGATCTTTTGTTTATAAGTGGGTAAACCGTGAATATCGTGTTCTTTTCACTAAAAACCAATTCCGACAGGCTTTGAAGCATGCAAATGTCACTAATATTAATAAACTATCGAAGGAACAATTTCTTTCTATTTTCAATAGTTACAAATTGTTTCACTAAATTAAAGTAATAAAGCGTTCTCTAAGTGCTAAAACAATAGCCAAATCAGGATCATAGCTTGGTTCCTGAATTTGTCCATTCTCAAATTCACCCCTGAGCCACTCACCGTATATAAATTCTCTTTTTGGAGGATATTGCCAAGGGACAACTTCACTCCTATTTATAACCGTAACTTCAAGTGGTCTAACAGAATCCGTATTTCCAATCTTTCCTGATATAGTCATTAGTCTTTCTGTTAGTTTTTTTCGAGTTAATTGAGGTAAACTATGATTCACGACGACTAGAACATCTACATCGCTGTTAATGCGTAAACCACCATTTACTGCTGAACCAAATAGATATACTCCAACTATTGAACTTCCAAATAAATCTTTTACGATTTTTAATGTTTGAATCGCTTGATTTGGTATTTTTCCGTTAATCAAATTGCTCATGATTTCACCTCGTTGATTATGTTCATATAAAGTTTATATTGATACTCAATTTACTTACCCTAGATTGGACAAACTTCCAATGATTTGTTCTAAACGCTCTTTAACACGGCTATTAGTCTCTACTTGTCTTTGCCATTGTTTATCCTTAGCTATGGCTAATAACTCTTCTGTACGCTCTAACTGTTCTTCGTGCTGTGGTAAGAATTGCTTACTGGTACAGAAGTGAGTGCAATCTAAGCATGCATTCGCATGTGGACAACCACCTGCTACTACTGGCAATCTACAATAACCATTTGGAAGCACTTGTGCATTTATATTTTTCTTGAACCATTGAAGCTCTACATCATCGACTTCATTATCTTCATCTAGATCAAGCACATCTCCATTATTGGTAACCAGTTTTTCCTGAAATTTAGTAAATTCATTTTTTAGAGTTTCATCAAAGATATGAGCGTATCTGCTTGTCATTTCTGGGCTTTCATGCCCCAAAAATTTCTGCACAATATGCTGGGGCATCCCGTTGTTAATCATTCTTGTTCCTACTGTACAAACTTCCAATGATTTGTTCTAAACGCTCTTTAACACGGCTATTAGTCTCTACTTGTCTTTGCCATTGTTTATCCTTAGCTATGGCTAATAACTCTTCTGTACGCTCTAACTGTTCTTCGTGCTGTGGTAAGAATTGCTTACTGGTACAGAAGTGAGTGCAATCTAAGCATGCATTCGCATGTGGACAACCACCTGCTACTACTGGCAATCTACAATAACCATTTGGAAGCACTTGTGCATTTATATTTTTCTTGAACCATTGAAGCTCTACATCATCGACTTCATTATCTTCATCTAGATCAAGCACATCTCCATTATTGGTAACCAGTTTTTCCTGAAATTTAGTAAATTCATTTTTTAGAGTTTCATCAAAGATATGAGCGTATCTGCTTGTCATTTCTGGGCTTTCATGCCCCAAAAATTTCTGCACAATATGCTGGGGCATCCCGTTGTTAATCATTCTTGTTCCTACTGTAGAAGGAACATCATCCCATTCTAGCCTAAGAAGGGTACTAAATAGTCCTTCCAATATAGAGATCCTCCCAGTTATTGTACTAGGTTTTATTCCCATCATGTTTAGTTCACTTAAATATGCTTCAATTTCCACTCTCGTTAATTGGTGTACTCTCTGAACTTGTTTAAATTTCATGTCCAGAAAATTAAAGAACTCTTTAAGTCTTTGGGCAATATCACTTACATAGGAAAAGCTATCCACGTTCAATCTCAACTTACAATATCTTTTTACAAGTTGTTTAAAATATGTATTCCGAAACCCTTTAAAGTTAATTGTATATTCATATTGTGTTGGGTTAACCTTATCATCTGGCAAAGGTAAGTTACGTCTATCCCAAACGTCTTTATCCCACTCCTCTCCATCAAAATAAAAGTTCTCATAAAACTCCATAAATTGTTTTAGATTAGTAACATAGTAGGAATTAGCTTTTACAGGTGTTTGAGGTATTTATTAAACTCATTTTTCATATCCTGATCTGAAAGATGAACATAGGTATTTAACGTTGTCTGAACATGTGCGTGACCTAATCTCTTTTGAACGAACGCAACATCCCATCCTTCCCTAATTAGCTGCGTTGCGTGAGTGTGGCGAAGCATATGTGATGTAAATTCTATTCCAGTCCTTTTAACTATTCTTCTAACTAGATCAAGAACACTTTGGTACTTTAGTGGTTTCCCAAAATAGCCTTCTTTTAAGGAAATAAAAACATAATCATGCTCCAATTCCTCACTATACTCATATATCAAGTAATCTGTATAAAGTGACATAAGTTCTTTACTCACATGTATTGTTCTTTCCTTCCTTAATTTAATATAAGCTTCATTAACATTAACATCTCTAGGTGTTAAATGGATTTGATTGTCCCAAGTGACAATATCTTCAAGCCTAAGCGATAACACTTCACCGATTCTTAAACCATCTAAGTATTTAATAAATTTCATTACTGGTTCTATTAGCTGGTATTCTTTATCTAGTAATAAATACAATGGATACGGCTTATTCTCCACTTCTATCCTTTGAACCTTCACATGTTCCCACCTCTTTAAATACTTTAACTACTACAAATTATAAACCTTGTTAATTTTTATTTAAAGTAAAATATCCCTTTAATATCTCCTCTTAAACTACTTTAACTACTATTATTTATTATACTATGGTTAATACATCTCCACTTGGATGATTATGACCGAGCATTATACTATTTGCGTTACTGAGTATCGCTGTTTTGAATATTTCTCTAGGGTGAATCACCGTTTGGTTAATAGATCCAATCGATAGTGTTTGAATATGTGTAGGTTCATTTTTACTGTTCATACATATGAGAATGAGATGCTCTCGGTCACTGTTTCCAATGAATGAACGCATGATTTCTGCCGCATCCTCAGGGTTTGAAATAACATCGTTATCACTGTACAAGCGGGTTTCTTTTCATCCCATGTTTTCTTGAGTAAATAGCGGTGTTTTTCATCCTTGCTAAATATAGCTTCTGTGTATATCGTATTTTTGATTGTATTCATATATATAATCACTTCCTTTAGTATTCTTCTGGTAAAAGCATCACATAATAAAAAGCGTCTACGCCATCTTCACGAATGACGTAGACTTTCTTAGGTAATGCATTTTGATTTTTTACATAGTTTGTATAGTGATATTCCAATTTGTATGCAGGTTGTTCTTGTTCATGTGTGATTGAGAGTATATTCTCATCTTCTTGCAGTTTAAAAATGTGTAGGTAATCTGTATGAGGTTGATTATCTCTTTCTTTTACCATATTCCAAAGTAAGATTTGAAGGTCTAGAGATAGGTATTCACTAATACCTCTTGTGATGTATCGATTGATTTTCATGTTATTTTACCTCGTCTTGAATTTCTTTTGATTTGTCATTTATTACGCATCCCGGTGAGAATGAGAGAAAATTCCATATGAAAAACCGCTTCAAACCTTGGTATGACAAGGAAATCCCGAAATTCCGCCTATTTTGACGAACAATCAACTCATTCTTTATAACTATTGATGTTAGGGTGGGGCTCTGCTTTCTTATATATTATTTATTTATAAAGAATAACGGGATTTTGGGATTGTGCTTGCACAATCCTTCTGCTTCTTCGAATCTGCAAATCCCAATCATTTCCCGATAAAAAATCATTGTGGGATGTTCTTTAGCAATTTCAATATAAGCATCGTGTAGTTATGAAAAAAATTACGACAATGACTGTTTCATTAGATAAGTGTTATTGAAATTGATAAAGAGAATTTTAAAAATGGTTAGATAAAATAAATGAAAGAATATAATGAAAATTATTGTTATAACAATGATTCTATTAGCTAAATAGTAAGATATAGTGTTTGGGTGATTTGTCATTTATTACGCATCCCGGTGAGAATGAGAGAAAATTCCATATGAAAAACCGCTTCAAACCTTGGTATGACAAGGAAATCCCGAAATTCCGCCTATTTTGACGAACAATCAACTCATTCTTTATAACTATTGATGTTAGGGTGGGGCTCTGCTTTCTTATATATTATTTATTTATAAAGAATAACGGGATTTTGGGATTGTGCTTGCACAATCCTTCTGCTTCTTCGAATCTGCAAATCCCAATCATTTCCCGATAAAAAATCATTGTGGGATGTTCTTTAGCAATTTCAATATAAGCATCGTGTAGTTATGAAAAAAATTACGACAATGACTGTTTCATTAGATAAGTGTTATTGAAATTGATAAAGAGAATTTTAAAAATGGTTAGATAAAATAAATGAAAGAATATAATGAAAATTATTGTTATAACAATGATTCTATTAGCTAAATAGTAAGATATAGTGTTTGGGCGTGTGTTACTACGCGTTGAATGACTTTATCACTTTTGACTATTTCAAGTATTTGCTTCATCACATAATCTTCAATCACATCAGCTCTTACACTGTTTGCCGAACATACTTTGGAACCCTTGTTCCGAAAATTACTACATGAATAGTAACGAATACGTTTCTTAGTCCCGTCTTTAAGTGTATTCGTGGTATTGCTTGCTGCCATAGGTGCGCCACATTGGGGACAGTGAATAATGCCTGTAAGCAGATTCGTTCCTTTGCCATGGACTTGGGGTTTTTGACTGACTTGTTTTTTACGCATTTGTACTTTATCCCATAAATCTTGATTAATAATGGGGGAATGCTTACCTTCAGCTATCACTGGTTTATCATTAAGCCCTTTACGACGTTTTTCACTCCAATCTTTGTATTTCGCAAATTGAATTTTGCCGATATAGAATGGGTTAGCTAATATATATGTGATAGAACTAATACTAAACATAGATTTACCTGAAATACCACGGTCAGCGTATATATCTTTAACTTCAAAATGATGGAAGTCACAGTATTCTTTGATTTGATTGATTTGTCCGTCGATACTATAACCTTCTGTGCTTTGCATTTCTGTTGAAACACGTACATAGATACCGACACGTTTTGTTTTAAGTTGTTGCATTATGTTTCATCCTTTCTTCATTTATGCAATTGACGATTGCGTTGTTTGATTGACGATGTTTAAGGGTTCATTTTTGAAATAGATACCCATTAGTGTTTTACTTTTTGTGATAAGAATTTCATCAATGTAGGGATACAGCATGTTTAACGTGAAACGTTTTTGAATAATATTTTGAATGGTGTTTTGTATTTGATGCCCATTGATAGATGTAGTGCGTTGCGGTTGTTGACGTAATGATTGCGTTTGTTCTCTGAACGTTTCTGCATCAATGATGCCTTGTGCCAACTTTTCTATCAGTTGTGTGTTATCTTCTTCTAATAACTGTGCAATTTTCTTATAACCATGACCTTTAATGTAATAATTGAATACAGCCTTTACCGTTGGTGACTCATTTTGATTGATGATGAATGTTCCGTTGTGATATTCGTAACCAAAGGGCGCATGGGTTGTAATCAATCGACCTTGCTTTGCTTTTTCTTGAAGCCCATTTCTGACTTGTTCTCCAATGTTATCTGATTCAAGTTCGGCCAAGCTGATAAAAATATTAAGCTTGAATCGGTCGAAAGCTTGATCCATATCAAAATAACCATCATGCACACTTAAGATATGAACACGATATGTTTGACATAATTTGATGAGTTTTAATGCATTTTTCAAATTACGATGCAACCTATTAAGACGATAACAGCATAATATGTCACACTGTCCTTGTTGAATTAATTGTGTTATTTGTCGATACCCACTACGATTATCTTTGCGTCCTGATTGTTTGTCGCTATTCCGAGGATAGATGCAAACTCTACATCTAATTTTAGATGGTAAAATACAAGTGATTGTTTTTTACCGCTATTATCTTTGACACTTCTTTTAGTTGTTTGGCGTCCACGGTCAGCTAATATGAAACCTTTATCTCTTAAGGCGTTGACAACATTATTAACATCTTGAAATTGATGATTGTTTAGCATCTGTTTAAAAACGTTCGCAATCATTTTTACTTCGATATGGTCATCTTTTAATGAGATTAATCCATAGTTCTCAAACATATTTTTCAAAGCACCTTCATCTGAAAACTTACCTCTGTTTTGTGCCACAAATTGAATGATGACATCAATAGCTTTATCAGCTAATGAGCGTTCAGAGACTGTATGAGTATGATAATCAATAAAGTAGTCTCTTATATTAGCGATATCAATATCTGTAGATAAAACACGACCTAATATTTTCGCAGATGTTGTAATGACTGCATAACGCTTAAACAAGAGAGTTTCATTACCTTTGGTAGGGTTACCAGCGACTGATACAGCTAAAGAAGCTGCAGTTGACTTACCGGTTGAGGATTGACCTGTAAAACTAAAAATGATTCCGGCAAATTCGGTTTCATGTTTGTGCTTCAGGAAACTCGTCACTAAGGCAGAAATACCAAATACGACTGCTAATTCTAAAAGAAGAGAACCTTTAACCTCTTTTAGATACATGTTAAACCAATTATCAAATGTACCTTTAGGAGTTAAGTCATAAGGATTATCACAAATGGCGTCAGATGGAGATTTATTATCAAATTCTTTAGTAGTATAGATTTCACTTAACGATACAATAGGACCAAACGGTGTTTCCAGTATACCTACCCCTTCATATAAGTAGGAAATGGGTAATTGATTGCGCATTTGTTGCAACGCATAACCTAAATCTTTTGTATATTTTTCATTAATACTAAATCCATACTTCATTAAAGATGGAATGAAATACCTAATATTTTCTTTTTTAACTGCTCGAATTTATCTGATTGATTGAAATACATTTAACTTCCTCCTACTAATGAACTAAGATAGGAAAATTAAATATGCGCACAATTAACTTTCTTAAGTTCATTTTAGCCAAGAAGTTATCATTTGAAAGCTTGTAAAAATATGTTAGAAATTCCGTACTAAATTAAGATGGATTTTTGTTGACAAAATAAAAAACGCTGATTTAACAGCGCTTTAAATAAAAATTAATCTGAAGTTATATAAAAGTAGTCAGAAGGAGTGGTGTTATTATCATTATAATAATCTAGTGCTTTATTGATTTCTTTTATTAATTTATCATGATGTTCTTTTGTTATTTTCTTTGGATATTTGAGTTCTTTTTCTTCTAAGTCTTTTGGAGACACTAGGTCACTATTTAAAATTAATGATAACAGCATATTTTTAGGTGCCGAAGCTCTGGTGTCTCGAATTCCTAGAGCGTTGCAGAATTTATTAAAATTAGTTGTAAAATTATTTTTTTCTTGAATAAACATGTCGTTGTCATTTAATTCTGAACTATGATTTTTAATCATATTGATATTTTCTTCAATCTTGTCACTACTTAAATTTTCCATGCAAAGTATACTATATCTTACTATATCACTTATATTTATGGAAAAATCTTTAGGAGAACGATTTAAAGTATCCTTTTTATTATCTTGATCTACAGCCCTACATGAATCATCAAAAACTTCTTTGACATTTATTTTATCAATGTTCAAAATTATGTCTACTAAAGCATTTTGAAAATCATCGCTATATATGTCTTTATTATTCATAGTGTCACTACCTTTATTTTTAATAACACTATATATTATATCTTATAAACCTAATACCATGAAGAATAAAAAGAATGATTCAAATTTTATATTTAATCCATAGTTGGCTGCTATGGTTAGTGTACTAGTGTTTATCATCTATTTTATACGCCACAATTTCTCCGTTATAAATATCCATTATCGAAGATAAATACAACATAGAATGATCAAATGGTAAATAAGTAATATCGGTTGTTAATACTTCTATGGGACAATTCGCTTTAAATTATCTTTGTAATAAATTGTCTGTTTTATAATACGGTTTACCTATCCTTGTCGTCTTTTTAGGTCTAACTCGGCAGTTCAAATGATGCTTCTGCATCATTCTCTGTACTCTCTTATGATTAATTGGTGATGTATAACATTGATTAATCAGTGCTGTAATCTTACGATAACCGTAGGTATAATGGTTAGCTTCACATAATTCAATAACTTTTTGTGTTACAGTATCATTTTTATAGGTTTTGTTTTTCCATCGGTAATATGTTGATTTAGGTATATTTAATACTTCTAGTATCAATTTGATTGAATAGTTTCCTTTTAATTGATCCACTAAATCTATGACTATTACTAAGTGGATAAAGATATTAGAAAAACGAGAAGCAGGACAGTTATTAAATCGGTAGATATTAATCATAAGTATTTAACTGAATTTTTACCTTTTGTCGAATATATAACTAAAGTTGAAGGTAGTAAAATATTTATCTAGTCGATATTAAAACAATTTATCGAAAACGATGGTTTTCCATATCCTCTTTAGTAGCAATTTTCTAACAATATATAATTAATTATATACAAATTAAGAATAATTAAGAAGTATATATTAATTAGAGATAGTTTAAAAATTAGATTTCAATCAATTAATTAAAACAGGTTAGACTATTAATTTATACTAACCTGTTAAAAGTAACAAAATTAAGAATATATTAAAACTTGTGTAATGAGTAAGCCTCCACCAAATATTAAAACAAACGCGACAACAGGCCATACGAAACGTAACCAGTGTGAGTAGCGCACGTTTAACATTTGAAGTGTTGCCATTACAGGGAATGGTAGGACGAAAAGCGTAAGAATAATCTTTTTACGTAATGTAAACTCAGAAGAACCGTCATCATGGAGCACAGACCACTGTTTTTCAAATGCTGCTTTGTCTTCATAAGAATAAGAGGATTTAGGATCTTTTTTAATTTTTTTACAATACCAGAATAAATAACTAATAACAAATATGGCACCGATGATACAAGCGCCTATTCTCCAATAAAGACCATCAGTAAAAGTTGTTCCTGCTGCATTAGAAGCAATGACGACTGAGAATGGGTTGATTGTTGAGAATGTACTACCCACAGAGCTTGCTAAGAAAATTGCACCGAAAGTAAGACTTTAGAATCTATGGGAAAGATAATAAGGTTTAATAGAAATACAAGAAGTGTAAATAGTAAGCATATAATTTATACATTTTAATATAATATAACAAGAAAGGTAAACACAAAGATAATAAAAATAAAAATTTAATAAAGATAGAGAGGTAAACTATGACAAGAAGTCATCAAGGTTATCAAATAAATATATCCCAGCGGTTGAGACGACTCACTGCTGGGATTTTATTGTTAGTTATTTATTCTAAGTGTTGCATTTGGTAGCCGATTCTAGGATGTGTGATGATTAATTTCTTTTCAGTGTTTGGGTCTTGCGTATAATTCAACTTTTTACGTAAAGAGGCCATATGTACACGTAAGGCAGCCATTTCTGTATGATTGACATAGCCATAGAGTGATTTTAATAACACTTGATAGGTTAATACTTTGCCGACATGATGGCATAATATCGTTAGGAGTTGGAATTCATTCGGTGTTAGATGTACGGACTGTTCATTGACAAGGACTGATTTCGCATCGAAATCAATGGTTAATGGACCATTTGTGAAACGACTTTGAATTGTCTCAGTAGAACGTGACATACGTAATGCTACTCTGATACGTGCTCTTAACTCATCGATATTGATTGTCTCCTGAATAATAGGGATTAAAAATCAATTGACGTTCTTCTTCTGGAATACCTTTTCCGCAATCTATCATTTCGAATTTTATTTTGTTTGTTTCATGTTGAACGTGCAGTTTTATTTCAGAATGTGATTCTGCATGCTTTAAAGCATTATCGATAAGGTTGAATAGCACTTGCAGTATTAATTTACTGTCGATATTAATGAGTGAAGCGTCATCCTCATTTTCAATAATGACATGATTTGCTTGGTGTCTGCGTATGAGGCCTTCTTCAAATTCTTCTAGAAGTTCTTCTACTAAATAAGGGGTGCGTTGTATTTGAATGTCAGAGCTTTCTAACTTAGTCAAAGATAAAATATTTGTGACTAAGGTATGCAGATATTGTGCTTCGCCATAAGAAGCAGTTAAGAGTTCTGCTTGTTGTTGATCGTTTAAATGCTCGTTATGGTATTTCAGCATATCTAAGTTGCCCATAATGGAAGATTCTTTAATGGACTGGTTAAATTGCAGCATAATATTGGTCCGATATAACTGCCGTTCTGTTAAGGAATGCTGATGTTTTAAATTCTTTAAGATGGCACTCGTAAAGATACTAGCAAAAATACTGGTCGCAAACGTAATCGGATATTCAAAGCGATACATTTCTAAAGTGAATCTTGGCACCGTAAAGAAATAATTAAAAACAAACACATTTAAGATAGACGCAAAGAATCCGATTAAATAGGATTGGGTCCAAATAGAAAGCACGATAATACCGATAAAGAACATCAGCAAGATAATGGCACTGGATTCGCTTTTATCTAAGTTGTAAACCCATATACCGAGCAAGACACAGATCGTTTGAATTACAAGCATCTTCATAATCTCTACAGTTAAACGAGAGGATTTTTGAGCTTGCTTAGGTGTATTTGTAGGTTTGTCTGAATGAATATAATGAATCGGTACAATTTCTAACTTAAAGGCTGTTTCTAAGCGTTCTTTTTTATATACTTTTCCTGCTTTAAGGCGCTGAATCAACATATTTGGTGAAATATCCACAACTTCAAAGGCATCTGCTGACGTAATGAATTGGTCGGGCACACGTTCTGTAACTTGAATACCTGTCATTAACGCAATTTGTCCGCTTAGACTCTCGATATGTTGGATGTTGAGTGTTGTCCAGACATCGATACCATGCGATAGAATTTCTTCTATATCCTTATAACGTTTTAAATGGCGCTCTTTTGAAATGTTTGTATGTGCTAGTTCATCAATTAAGACCACATCTGGATTAGCTTCTATGATTTTAGAGACATCTATATAGTGAAAGGTGTGGCTGCCAAATTTACGGCTGGAGGTCGAAATTTCAGGCAATTGTTGAACCAGTGCATTGGTTTCAGGGCGTTGATGGGGTTCGATATAACCAATTTTAATATCTGCACCTTCTTGATACTGAAAAGGCTGTTTCTAAGCGTTCTTTTTTATATACTTTTCCTGCTTTAAGGCGCTGAATCAACATATTTGGTGAAATATCCACAACTTCAAAGGCATCTGCTGACGTAATGAATTGGTCGGGCACACGTTCTGTAACTTGAATACCTGTCATTAACGCAATTTGTCCGCTTAGACTCTCGATATGTTGGATGTTGAGTGTTGTCCAGACATCGATACCATGCGATAGAATTTCTTCTATATCCTTATAACGTTTTAAATGGCGCTCTTTTGAAATGTTTGTATGTGCTAGTTCATCAATTAAGACCACATCTGGATTAGCTTCTATGATTTTAGAGACATCTATATAGTGAAAGGTGTGGCTGCCAAATTTACGGCTGGAGGTCGAAATTTCAGGCAATTGTTGAACCAGTGCATTGGTTTCAGGGCGTTGATGGGGTTCGATATAACCAATTTTAATATCTGCACCTTCTTGATACTGAATCCGATTGAGAAATTGATTTATCAACTGATTGGCACGAAATTAGAACACATGTCTGGGAAGACGTATATCAAACATTTTTTGTTGTTTAACGGATTGATGGGCGGATTGTCCTTTGTATTATTGCTTATTCAACAATGGCTGTTTTTGAATCCTAACCATAATTTAAATCAATCTGTATCGTTAGCCTTTAATACTATGGCATCTTTTTTGACCAATACTAACTTACAGCATTATGCAGGTGAAACAGATTTAAGTTATTTAACACAAATGTGTGTCATCACTTTCTTAATGTTCACGTCAGCAGCGTCAGGTTACGCCGTATGTATTGCGATGTTAAGACGTTTGACTGGAATGACAGATGTGATTGGTAATTTCTATCAAGATATTACGCGTTTTATTGTACGGGTGCTCATACCTTTCGCATTGATCATCAGTTTGTTTTTAATCAGTCAGGGCACACCGCAAACGCTTAAAGGACCGCTAGGCGGCATGGTTCCAATGGTATTAATGATGTTGAATGCAGTTTTTGGCGGTGAAGGTGTTGGGCTGATGAACATGTTGATTTATGTCATGTTAACGGTCTTTATCTGTAGTTTGATGATTGGGAAAACACCAAGTTATTTAGGAATGAAGATTGAAGGTAAAGAGATGAAACTCATTGCGCTTTCTTTCTTAGTACATCCTTTACTTATTTTGGTTTTTTCAGCACTAGCTTTTATTGTGCCAGGGGCATCAGATGCGTTAACTAATCCGCAATTCCACGGTGTATCACAAGTGTTGTATGAGTTTACATCATCTTCAGCGAATAATGGCTCTGGTTTTGAAGGATTAGGAGACAATACGGTATTTTGGAACATTTCAACAGGCATTGTGATGTTGCTTGCACGATATATTCCAATCGTTTTACAAATTTTGATTGTATCTAGTTTGGTAAATAAAAAGACCTATCAGCAACGTCGTATTAAACAAGACGGCAGTTATGAAATGATTGACGCTAGTGACCTGAAAAAAGGACATATCGTACGTGTCGCGACAGGTGAACAAATCCCAAATGACGGTAAAGTTATTAAGGGCCTCGCAACAGTGGATGAATCTGCGATTACAGGTGAATCTGCACCTGTAATCAAAGAAAGCGGTGGAGATTTCGATAATGTAATTGGAGGAACTTCTGTAGCTTCAGACTGGTTAGAAGTTGAGATTACTTCAGAACCAGGTCATTCATTTTTAGATAAAATGATTGGTTTGGTTGAAGGGGCTACAAGAAAGAAAACACCTAATGAAATTGCGTTATTTACTTTATTGATGACATTAACGATTATCTTCTTGGTCGTTATTTTAACGATGTATCCATTGGCGAAATTCCTGAATTTCAATTTATCCATTGCGATGCTGATTGCTTTGGCTGTGTGTTTAATTCCAACAACCATTGGGGTGGTTGTGCTTGAAGATAATGAGATTTTAGGTGTTATTTATTTGAAAGATGTCATTAAAGATGGACTCGTAGAACGTTTCCGTGAATTACGTGAGATGGGGATTGAAACGGTGATGTGTACAGGAGATAACGAATTGACAGCTGCGACAATAGCGAAAGAAGCGGGTGTGGATCGCTTTGTGGCAGAGTGTAAACCTGAAGATAAAATCAATGTGATTAGAGAAGAACAAGCGAAAGGTCATATTGTTGCGATGACGGGTGACGGTACGAATGACGCGCCAGCTTTAGCAGAAGCTAATGTAGGTTTGGCAATGAACTCAGGAACCATGAGTGCCAAAGAAGCGGCGAATTTAATTGATTTAGATTCTAATCCAACCAAACTGATGGAAGTCGTTCTAATTGGGAAACAATTATTAATGACACGTGGCTCACTCACTACATTTAGTATTGCGAATGACATTGCGAAATACTTTGCGATTAAATATTTCCATGGACGTATCAGTGCAGTCAATTACAATATGAATGCGAATGAAGTGAAAGAAAGTGGCGGACCTGCTTCAGGCGGCTCAAACTACGGCAATTCAAATCCTGAATTGAAAAAAAGAGTTCAAGAGACTATTAAACAAGAAGGAAAAAAATTTCAAGTGATGCGGTGACCGCTTCTGGCTCTGGTTTAGACCCAGATATTACGGTTGACAATGCGAAACAACAAGTAAAACGCATTGCGAAAGAAAGAAACATAGATGCTTCAAAAATTAATCACCTTATTGATGAAAACAAACAAGCATCACCAATGGCAGATGATTATGTTAATGTCTTAAAATTGAATATCACTTTAGATAAACTCTAAATAAACAGGGAGTGAGGTGAGACATCCATGTGGTTCATTAGCATTATTATTTTAATAGCATTCCTAATTATATTAATGATTGACGATTTAATTAAAACATGACAACTAAATATTTCCATGGACGTATCAGTGCAGTCAATTACAATATGAATGCGAATGAAGTGAAAGAAAGTGGCGGACCTGCTTCAGGCGGCTCAAACTACGGCAATTCAAATCCTGAATTGAAAAAAAGAGTTCAAGAGACTATTAAACAAGAAGGAAAAAAATTTCAAGTGATGCGGTGACCGCTTCTGGCTCTGGTTTAGACCCAGATATTACGGTTGACAATGCGAAACAACAAGTAAAACGCATTGCGAAAGAAAGAAACATAGATGCTTCAAAAATTAATCACCTTATTGATGAAAACAAACAAGCATCACCAATGGCAGATGATTATGTTAATGTCTTAAAATTGAATATCACTTTAGATAAACTCTAAATAAACAGGGAGTGAGGTGAGACATCCATGTGGTTCATTAGCATTATTATTTTAATAGCATTCCTAATTATATTAATGATTGACGATTTAATTAAAACATGACAACAAACTCCTCTAAGTTTGTGTTTTTAAACTGTGATGGATTTGAATGTTTTTGAATTACGTTGTCGCGTCCTTGGGATTGCAATCCAAGAACGTCAGCATAATCTAAATCAATTTTGATTTGGTAGAAGACAAGAGAAGTACTTTTGCCTGTATCATCTTTCGCATTTCTTTTTGTTGTCTTTCGATCCCGATCGGAAACTAATTTTCCTGCATTATCCAAAGCATCAATAACATTTTTCGTGTCTTCGAATTGACTGTCTGTTAACATCTTATCGAATACATTTCGGATAATTTTTACTTCGATGTAGTCATCTTTAAGTGAGAGGATACCAAAGTTTTGAATCATATTAGCAAGACGTGTTTGTTGTGAAAACTTGCCCAGGTTTTCCGCAATAAACTGTACGATTGTATCCATCGCTTTATCTGCAAGAGAACGTTCTGACACCGTTTCATTATGATAGCTTAATAAATAGTTCTTTAATTCATCTAATACTATGGGTACACCATAATTTCCGCTAAGATATCCTTCTAGTGCATTTCTTGTTGCATTCCAACTCCGGAATAGGTTTTCAGTACCTTTTGTTGGGTTGCCAGCTACCGATGCGGCTAACATAGCGGCTGTCGATTTTCCTGTTGATGATTGGCCAGTGAAAGAGAAAATAGTTCCTGAAAACTCGACGTTATTATGATACTTAAGGAAAGCAGTGACTAATGAAGATACGCCAAACAACACATCTAGTTCTAAAGATAAGTTCCCATGGACTTCTTCTTTATACATTTGTAACCATTCTGATAAATTGCCTTTTGGTATTAAATCGTACTTGTTATCACATATAATAGAAGTGCTATTAGTAATCTCATTAGAAAAATAAGGCTGGTCTAATGAAATTAATGGTCCAAGTAATGTATGAAGCATTCCTACACCTGAGTATATTGTTGATAAAGGTGTGGTGCTTCTAACTGTAATTATAAGGTTTAGTAATGGCAATTTTTTATTTAAACAAATTTTTACGAATGGATTGTCTGTTTATTAATTCAGCAACGTTTATTGAAGAAAAATAAGTGTCTTCTGATAATTGCAAAGGGTTTAATTCAATGTAAACTGAATTAAGGGTAGGGTAGGTATGCCTGTTTTTTGGTTCTTTTAAGTTCAATCGATTAATAAAATTGTTGAACCTTTGTTCTAAGTCATACAAAAACATCAGTAATTCATTAGGAGAATGATTTATTATGCAATCCATATTTTCGTTTATGCTTGAAGTTATACATCTAAAAACAGTATTGGTTTCTTCGTATAAAAATAACTTATTAATAGAGGTAACATTGATTAAGACTGAGTATACGTATAATAAGAGTGACTCTGACATCTCATTTAGATAAATAAGACTGTGATCATTCTTATTTACGATTATTATATGTGATTGAATCAATTCAATTCTAAGATGTCAAATTTTTTGTTTCGATTGGTATTTTTTTAAAATGTGCCTTGTATTTTTGGGGTTGTTCCAAATGTGTATTTGCTAGACTACCTGTAATTGATATTGCTTTATTTAGCATTTGGTGTGTATTAACTGTATCTGATTCTTCTGGAAATTTAAATCTAAAAGTAAAATCTCTACTACCGAATGTACTTTTTACGGCTACAGTTTTGTACTTATGCTCAGGCAATGTAATTAAACCATCTTGATGCAGGAGGAAAAGTGTGTCATCATTTAATTTCTCAATTGTATTAAATAAGTAATTATGCATAGCCTCTTTATACATGGCGAATTGATAATTTAGATTATCCCATTCTATTAGTTGATTTAAAATACAATATAGACCTTCATTCAATCGGTTTACGAATATCAATACAGCTTCTTCTCGTCCAACAAGGCTTATTAACTCCTTCAAGTCATCCTTTAATTTTAATTATTTTTCACATTAATTTTAAGCAATCACTATATTAAGTATGAACTGAAAATTGACGAGGTTGAAGCAGCAAAGCAGGCTGCTAAAGCACTTAAGTTGTTCAACAAAAGATTAAATCATTATGGGTACTACATAACAGGAACTAACAATGCTAGATATTTTATGGATAAGGATGAAGATACGGAGTCTATTGGTTATGGAGGGTATGCGAATATTTATTTACAGAAGTCTACAGGTCTTGCTGTAAAAAAATTGAAAGAGGAGTATCTTACTGATTCTTCAATTAAAAGTAGGTTTAAGAGAGAATTTGATCTCACTAAATCTTTTGATACAAATCCATTGTTCATTAATGTGTTTGAATTTAATGAATCAGATTATTCATACACGATGGAGTTAGCTGATGAAACTTTGAAAGATTACATTGAAAGCAAGACAATTAGTGAGCTAGAAAAAGTAAAGATAATAATGAAAATTTTAAAACGAAGTGATGAACAATTATGTCAAATGGTTCTAAGTTCTAATAATAATGAGCAAGCGTGTTTAATTCGTTATATGCAAAAAAACGAATCTTCAGCATGTGATTTAATAGAGAGTATTAATAGAAAGTATCAAGAGTTTTGTGGAAGGTTTGAAGACTACGATCCTTTTGCTAAATTAGCATATATGATTTTATGTAATAACTTCAGTTATAGAGTGAATGAAACAGCAGCTAGAGTGCTAAATTATGTTGCTTGGTCTGTAAATAGATTTTCGGCACAAGACTTAATTAAAGGTTTAATTAATAGAGGAGTGGAGCCTTTGATTGAAGAAAAATTAAAGGACAATTAAAAAAACCTCATCATTAACTGATACGCAGAGGCGTATCACAAATAAAACTAAAAATGGAGTAACTATTAATATAGTATAAATTCAATATGGTGATAAAAACAGCAAAAAAATAAAATATAACATCATAAAGAGTAATAGCTATTTATGAAAAAAATTTAAAAGATGCTAAAAAAATAGAGCATAATATAGAAAGTATAAGAAATTTTGTAGCGAATGATGAAACACTTTATAATAAATATAATAGCATTTATGAAGTTATGATTCCAAGCCTAAAAATTGAAACTTATGATGTAGATAGATTAACAAAGATTTTACAAAATAATTATACAGATATAAAAATTCCTAGTTTTGAAGTTATAGATTGGTTGCGTAATGGTTTAGAATTGCATAATGTTGAAGAGAGTATATGTAAATTTTGTGGAAACAATTTAAATTATAATTTGATTAAAGAAAAAATAGAAATATATTTATTAAATGAAAAGAAAAAAGATTTTGATTATCTTAAAGATGTCGAAAAATCAATTGAACAATTATCGGATAATTATGAACAATATTTATCTAATATTGATATATTTGTTAATGAATTAGGGGTCCAAAAGTCAGTAGAAATATCACTAAATATAAAAGATATAAGTGAAGGAGAGAAAAATCTAATAGCATTTTTATTCTTTTATTTTGAACTTTTTGAGGATGAGAAACAAGAAACCATTAAAAGTAACATTAAAACGTTAATCATTGATGATCCTATTAATAGCTTCGACGAAGCAAATAGATTTTACGTTTTAGAATTAATTAAAAAAGTACTTAAAAGCAAATTTAATCAAATATTTATATTTACCCATTCTTGGAATGACTTTTGTGATATAACTTATAGATTAAAAGGGGAAGATCATAATTTTTATGAAGTGTACAAAGATCATCAGGGAACTAGTTTTTTAGAAAAATTTAAGAAAGTAAAGACGCCTTATAAAAAGTTATTTCAAGAGATTTACGAGTTATCGAGAAAAAGTCAAAAGGACATAGTTGAGGAAGATTGTTATTACTATCATTCAATAAATAGCATTAGAAGAGTGTTTGAAGAATTTTAATACCTGTGGAATTTCATTTGATTATGACAAGAGAAAGAAGATTATTTAGTTCAGAGTTTAAGTTACAAATGGTTAGATTATATGAAAATGGTAAGCCTAGGAATGAAATTATACGCGAGTATGATTTAACACCTTCGCCGTTAGGAAAATGGATAAAGCAATATCAAAACACGGGTACATTCAATCACCAAGATAACTTATCAGATGAAGAAAAAGAGCTGATTAAATTACGTAAAGAAGTTCAACATTTAAAAATGGAGAACGATATTTTAAAGCAAGCAGCGTTGATCATGGGACGAAAATAGAAGTCATTCAAAAGAATGCACATCAATATTCAGTATCAGCAATGGGTAACGTCTTAAAAATACTAAGAAGTACCTATTATGATTCTATAAAAAGAAAAGATAATAAAATCACTAAAGATGATTCAAACGTAGAACGTGCCGTCATAAATATTTTTAATGCTAATAGAAAAGgenAATACCTGTGGAATTTCATTTGATTATGACAAGAGAAAGAAGATTATTTAGTTCAGAGTTTAAGTTACAAATGGTTAGATTATATGAAAATGGTAAGCCTAGGAATGAAATTATACGCGAGTATGATTTAACACCTTCGCCGTTAGGAAAATGGATAAAGCAATATCAAAACACGGGTACATTCAATCACCAAGATAACTTATCAGATGAAGAAAAAGAGCTGATTAAATTACGTAAAGAAGTTCAACATTTAAAAATGGAGAACGATATTTTAAAGCAAGCAGCGTTGATCATGGGACGAAAATAGAAGTCATTCAAAAGAATGCACATCAATATTCAGTATCAGCAATGGGTAACGTCTTAAAAATACTAAGAAGTACCTATTATGATTCTATAAAAAGAAAAGATAATAAAATCACTAAAGATGATTCAAACGTAGAACGTGCCGTCATAAATATTTTTAATGCTAATAGAAAAGGTCCTTATGATAACGCAGTTGCGGAAGCAACGATGAAAGCAATGAAAACCGAATTTGTAAAACAAATGCAATTTGAAAACTTAGAACAGTTAAAAACAGAATTATTTGATTATGTAAATTGGTACAACAATTTTAGACCACATTCTTCATTACAGTATTTGACGCCAGTGGCATTTAAAAATCTACACATGAAAACTGTCTAAAAAAATGTTGACATACCAATGAAATCTTGAAGGATAGCTTTTCATTTAGAGTAAAAGAAATTGCAACGATTATTCTCAATGAGATAGCATATTCTGTTAACAGATATCATGCTCAAAGATTAATTAAAGATATTATATCTATTGGAATTAAACCAATAATTGAGGATATTTTAAAAGGAGATAAATAATGGACAATAGCTTTTTAGAAAGCCTAAAAGAGATTTTAGAACCATATGATGATATAGAATCAAATAAAGATGGTTTTGTGTTTGGTGAAACTTCCAATTTAAACACTTTCTTGGTCGATAATTAATTGAGTCTAATGCATAGTTAAGTTGCTCTTGATTTACTTTAGCTAAGTCTGTTTTCTTAGGGAAAAATTCTCTTAGTAAACCATTGGTATTTTCATTTGTACCTCTTTGCCATGCGGAATATGGATCAGCGAAGTAGACATTAATATTAAATTGGTTTTCAATATTTTGATAACAAGAGAACTCTTTCCCTCTATCGACAGTAATAGTTTTAACGGCACCTTTAGGTAGATGTTTGATAAGGTTATTAATTGCCGTCTCCATAGAATTAGAGGAACGATCAGGCATAAGTACACAATAATAATAACGTGATTTTCTTTCTGCGAAAGTAGCAATGCACCCTTTACTTTTGCCTCTGCTGGATACAATTGTGTCAGCTTCCCAATGACCGAATGTATTACGTTTCTTTATTTCCTTAGGACGTTGTGAAATAGGACGGCCACAAAGTGCCAATTATGGGCATTTTTTATGAATTTTTATAGGTGTTGCACTTAATATTACAATCCGTCGAGTATAAAAATGAAATAGATAAAATTAAATCTAAAATTTTAAATGAAGAAGACGAGTTAGTAAAAAAATCATTGATGTTAACAATATTTGTATTATCGGAGAGCTATGTTAGTTCATTAATTGTTTCTAATTTACCTGAAAGAGATGAAAATTTAATAGATAAAGCGTATGAAAAAATTATTCAACAGTATATAAGTAAAAATATACGTACAAGAAATGGTAGAAAAGAACTAGTAAAAAATTTTTACAATACAGATCTACCAGCAATACCTCATACCAAATTGAGAGATGCCCTTGCTCACGAAATAAATAAAGTTGATTTAAAAAACAATCGTTTTAAATATGATAATAGTAGAGGTAATAGAAATGAAAATATTATAGAAGTTAGTATTGACGAAATAATTAATGAGTAATGTATTGATGGACATAGATCCTTTTACAATATTTGCATTATTTAATAAAAATTCCATGAGAGAAACTAATAAGGTAAAAATATTAACAGAATTAGCTTCGGAATTGAATATTAAGTCCAAAATTCCGTCAGTTTTTGACAGTATTCCAACAGTCAATAATCTGAATGCTACATATTATAATTTTAAAGATTATGGAAAAGATAATGATATAGAGACCTTGTGGACCTTATTTACTGCTGCATTAAATTTTGCGAATTATCCTTCAGAAGATAATAAATTAAAATTTATACATAGTTTTGATAAGAATATTACTAAAACAGGAAATGGGAATAGTAAGATTACGAGTGGTTTGTACTGGATTGCACCTGAAACTTTTGCTAACTTTGATTCACGTTCAATTTGGTACATTTTTGATACATATAAACTCCCTAAAGAATTGATTAATGAACAACTTAAACCAAAAGAAAAACTAACATTTGAACTGACTACAGGGACGTTCTATGATTTTTGTAAGAAAGCTGATAAAGACCGCGATAATGAATATTTTTTAATTATTGATGAAATTAATAGGGGTAATCTGAGTAAAATTTTTGGTGAATTATTTATGTTGATTGAAAGTGATAAAAGAGATGAAGAACTAATATTACTTTATAGCGGTGAGAGATTTTCTGTACCTAGAAATATTTATATTGTGGGAATGATGAATACAGCAGATCGTAGTTTAGCAATTTTAGATTATGCATTACGCAGACGCTTTGCGTTTTATAATATGCAACCGGCGTTTCATACAACTAAATTCAAAAAACTTCTTAAAGCAATTAATAATACTGAATTAGAGTCAGTAATTAATTGTATTGAAGGATTAAATAAAGAGATTGTTCAAGACGATATGTTAGGTAATGGCTTTGTTATTGGTCATAGTTATTTTAGCAATATTGAATGTATCGACAAAGgenTTTGAACTGACTACAGGGACGTTCTATGATTTTTGTAAGAAAGCTGATAAAGACCGCGATAATGAATATTTTTTAATTATTGATGAAATTAATAGGGGTAATCTGAGTAAAATTTTTGGTGAATTATTTATGTTGATTGAAAGTGATAAAAGAGATGAAGAACTAATATTACTTTATAGCGGTGAGAGATTTTCTGTACCTAGAAATATTTATATTGTGGGAATGATGAATACAGCAGATCGTAGTTTAGCAATTTTAGATTATGCATTACGCAGACGCTTTGCGTTTTATAATATGCAACCGGCGTTTCATACAACTAAATTCAAAAAACTTCTTAAAGCAATTAATAATACTGAATTAGAGTCAGTAATTAATTGTATTGAAGGATTAAATAAAGAGATTGTTCAAGACGATATGTTAGGTAATGGCTTTGTTATTGGTCATAGTTATTTTAGCAATATTGAATGTATCGACAAAGAATAAGATAAAGCTCCGAAAGTTATTAGTTCATTTTAATAATGTTGATACTTTAGATTATAGAAATATTCAATGGTATCATTCGTTTGATCGAAATAATCAGACGTATAAAATGTTAATATCTATATGCTATTTAATTTTTCAAGGAGTAATACAAACTGAAAGCAAGGGACAAAATGATCTTATGGTATTTGTAGACGAACAACAAATATCTCGGCTATATGAAAAATTTATTCTAGAGTACTATAAAAAAGAATTTCCAGAGCTTGTTGTAACATCATCAAATATTCAATGGTCATTAGATAATGATGATAACGTGAATATGCTTCCTGTAATGAGAAGTGATATTATGTTGAGATATAAAGATAAATGTCTAATTATCGATGCAAAATTTTATAAAAATACATTACACAATTATTATGATACTAAAAAGATCCATTCAACTAACCTGTATCAAATATTTACTTACGTGAAAAACCCGTTAGTCTTAAAAGTGATTAGTCGTATAACAGTAATTGCAATTTGTGAAAGTTAATTTTATAGTTGTATGACCAATTTTTAAATAAGATTATTAGGTAAGGCATAATAGCCCTGTTAAGTGATAAACGATACAAAAGTGATATATAGGAGGCGATATCATGATTACTATTGATTCAAAGATTAATAAACAAATCGCTAAAAACCTTTCACTTGAAGGTATGTATGTTACACGAGAACAGCAAATACAAATTCTTCATGCAATTAATAATGAGAAAGAAATTACAAATGAACTTATTCGTAAAATCGCTTTTAAATAATGAAATATATAGCAACTTTTCAAAAGGCATTAAACTATCTTGAAAAGTTGCTTATTAAATAATAATTGCTCAAATAAAAAACATATAAATGCTCTTACCAAAAAAATATTCGTAACTAAAATATTACAAAGTAATTAAAAAGTGTGATTACCCAAAAATCCCAATGTTGTATCATTATAATCTATCATTTATTCCTTACCTCTATAAAAAATGTCTCAAAAAACATATAAACAAATATAACCATTCAATCATTAAAGCATAAAGAACGCTACTTCATTTCCATTAATATTTATATAGAAAGTAAAGTAGCGTTATTCTAACTTATTTAGTTTATACCATAATATAATGTCTCTAGAATAAAACGCTAGTGATTATGGTTTTCTTCAATTTGATAAAATTCAATCGCATTGCCTCTTAATATACCATTAATCGTGTCAGGGTCAATATTACTGTTTTTAATATAGTCTACGCCGCGTGTATATTTTTCATCTTGGAAGTAAGGGAAGTCTGACCCCATCATAAATTTATCCTTACCAAATGTCTCAATAGAGTTAATCAATGAAGGTTCGTGGAAGTTTGCTGTATCATACCAAAATTGTCGATTTAATACTTCATAAGGATCAATATTAAAGGCATTCTCTTTAGTACCCCATTGTGGAGATTGTGGTGTCGCAGAAATAATTTGTAAATCTACGCCAGCATCGTCCATCATTTTGAAGCGTTTCTCTAAATCTTCTTTAGACGCAGATTGATTAATCCCTTTAGCAACTTCAGTACCTTGACTACCTAATTTGCCAAGTTTGTCTAAATAGTCTTCATTCCATAAATGTGCGTGTGTATCAATCGCTTTTGTTTCAGTCATATTATCCCCTCCATTAAAAATTGTCATTCATAATTTGCTTATTGCCAATAGCTTATTTATTACGAGTTAAGCTTAACACTTCTAGTAAGCTTAATACATTTAAAAAGAAAAATTTAGAAGCAGCTTGTGCACCTTTATAACCATGCCCAGCTTTATAATGGTTATAAATAGCTGTACCCATAACAATATTAATCATAATCGTACCAACAACTACTAATTTTTTCCCTAATTTACCGAAAATAGAAGTAAATAAA

    genAACTGAAAATGAAATAATCACATATAGTTGTGTTGTATTTTGACTAAATTGAGCCATTAATAATGCACCAATCATAATCGTTAGCATCCCCATAATACTCAAGATACGTCCACCAATTTTATCGAATAATTTACCAGTGACAGGCGATAACAGTCCCATAATTAACCCACCAGGTAATAAAATAAGTCCTGACTCTAACGGGGACCATTTCATCATCGTTTGCATATAAATTGGTAAGATTGTTAAATTCCCTATAAATAACATGAACATTAGTACAATTAAAATCATTGCCACTGAAAAGTCGTTATATTTAAATACTCTAAACTCTAACAATGGCGATTCCAGTTTTAATTGTCGGAAAATAAATACCGTTAATATAACTATGGCAGCAATAATAGTTATATAAACCATTGGATGTGACCAACCTAAGTTTCCTGCTGTACTAAAACCATATAGTAAGCCACCAAAGCTAACCGTCGTACTACTTGATACCGTAAAATCTTTCATAATTTCTGGAAGTATCGTAGTCATCAAAGTTTGATTCAGCACACCAACAAAAGCACCAATCATTACGACAGCTATAACACGGTTCCGTTGTTTCAAATCTATATTAAAGCATATACATTCCTCAAATTTTGACGCCTCCCTCTCTTTTAAGTGGAACCTACTATCATTTGTTTTATACGGAATACGTTCCGTTTGTCAATTTAATAACTCAAGGGTA