Phonons. Theory and Experiments IH. PeterBriesch. Springer-Verlag, New York, 1987. xii, 249 pp.,illus. $49. Springer Series in Solid State Sciences, 66.

Phosphollpid Bilayers. Physical Principles andModels. Gregor Cevc and Derek Marsh. Wiley-Intersci-ence, New York, 1987. xviii, 442 pp., illus. $79.95. CellBiology, vol. 5.

Physical Pocsses In Comets, Stars and ActiveGalaxies. W. Hillebrandt, E. Meyer-Hofmeister, andH.-C. Thomas, Eds. Spring-Verlag, New York, 1987.viii, 193 pp., illus. $41.50. From a workshop, Tegernsee,F.R.G., May 1986.

Plant and Planet. Anthony Huxley. 3rd ed. Penguin,New York, 1987. 480 pp., illus. Paper, $6.95.Proceedings of Groups-St Andrews 1965. E. F.

Robertson and C. M. Campbell, Eds. Cambridge Umn-versity Press, New York, 1987. x, 358 pp. Paper, $39.50.London Mathernatical Society Lecture Note Series, 121.From a conference, St. Andrews, Scotland, July-Aug.1985.Proceedings of the Fifth International Sympo-

sium on Trichoptera. (Lyon, Francc, July 1986.) Mi-chel Bournaud and Henri Tachet, Eds. Junk, Dordrecht,1987 (U.S. distributor, Kluwer, Norwell, MA). xxiv,397 pp., illus. $119.50. Series Entomologica, vol. 39.

Ratlonality. The Critical View. Joseph Agassi and IanCharles Jarvie, Eds. Nijhoff, Dordrecht, 1987 (U.S.distributor, Kluwer, Norwell, MA). xi, 477 pp. $89.50.Nijhoff International Philosophy Series, 23.

Reliability of instrumentation Systems for Safe-guarding and Control. J. P. Jansen and L. Boullart,Eds. Published for the International Federation ofAuto-matic Control by Pcrgamon, Ncw York, 1987. viii, 179pp., illus. $55. From a workshop, The Hague, May1986.Runes. R. I. Page. University of California Press,

Berkeley, CA, and British Museum, London, 1987. 64pp., illus. Paper, $6.95. Reading the Past, vol. 4.Solving Problems in Appid Thrmodynamics

and Energy Conversion. G. J. Sharpe. LongmanScientific, Harlow, U.K., and Wiley, Ncw York, 1987.xii, 216 pp., illus. Paper, $19.95. Solving ProblemsSecris.

POSITIONS WANTED

Biochemist, B.S. 1983. Experience in various biochemi-cal techniques including tissue culture, liver cell separa-tion, nucleic-acid hybridization, and enzymatic measure-ments. Published work and teaching experience. Preferswest coast of U.S. location, seeking position as researchassistant. Box 12, SCIENCE.

Director of major industrial toxicology laboratory/de-partment seeks challenging position. Ph.D. toxicologistwith broad expenence in safety asscssment, currentlymanaging staff of 200+, responsible for highly produc-tive research and testing programs. Extensive experiencein negotiating with federal and state regulatory agencies.Effective interaction with senior corporate management.Box 13, SCIENCE.

Law/Life Science. Reed College immnunology graduate.Five years of clinical research experience. Member of theOregon Bar seeks position combining legal and lifescience challenges. Box 10, SCIENCE.

POSITIONS WANTED

Geochemist, Ph.D. Young vigorous research associateseeks research industrial/academic position. Scvcn yearsof experience in radioisotope oceanography and sed-imentology (U, Th series, 7Be, '4C) in universities and1.5 years in atmospheric chemistry in health researchaboratory. Familiar with nuclcar instrumentation, GC,ratio-MS, computers, separation chemistry for trace ele-ments and gases from geological samples. Box 14, SCI-ENCE.

Nuclear Medicine Physician, Microbiologist, M.D.,Ph.D., A.B.N.M. (eligible). University-trained, avail-able 1 July 1988. Academic, industrial, or clinical oppor-tunities considered. Box 11, SCIENCE.

A Progressive Research position wanted to do researchon the redox nature of membrane depolarization-hyper-polarization by: Dr. Ghouri, Consuting Scientist andGeneral Tutor, 509 Connie Lange, Manchester, MO63011. Telephone: 314-394-0589 (evenings).

POSITIONS OPEN

ACADEMIC POSTIIONIN

MEMBRANE BIOLOGYDepartment of Physiology seeks applications for a

tenurc-track faculty position, in assistant professor work-ing in membrane biology. The Department tries tomaintain a good environment for serious research.

Please send a statement of your research plans anddreams, curriculum vitae, and the names of a few sacntistsfimiliar with you and your work, to: RS. EisenbgChairman, Dept of Physiology, Rush MedicalCollege, 1750 West Hrriso, Chiago, IL 60612.

ACADEMIC APPOINTMENT to a named profes-sorship in the Department of Ophthalmology with con-joint appointment in an appropriate basic science decpart-ment. Some research support provided. Strong basicinterest in pursuig aspects ofphysioloy, pharmacologyor biochemry of vision is essential. Zdidates shouldhave excellent basic science training and experience butneed not have prior training in vision research, andshould not currently be located in a Department ofOphthalmology. Publications and extramural fundingvital. Rank, at assistant through full professor, to beassigned based upon experience, etc. Please send curricu-lum vitae, five representative reprints, statement of re-search interests, and names of three refcrences to: Dr.Keith Green, Department of Ophthalmol1y, Medi-cal College of Georgia, August, GA 3091,Equa OpportuniylAffimative Actim Employr.

ADJUNCT ASSISTANT PROFESSOR OFHISTOCOMPATIBILITY AND

TRANSPLANTATION IMMUNOLOGYDEPARTMENT OF SURGERY, UCLA

Ph.D. or M.D. to conduct research in clinical trans-plantation, histocompatibility and transplantation inmu-nology. Position includes pre- and post-transplant assess-ment of immune responsiveness. Familiarity with flowcytometry, renal transplantation and histocompatibilitypreferred. Research productivity in immlunoogy evi-denced by publications essential. Experience in teachingstudents or research fellows required. Demonstratedexperience in biochemical, cellular and serological tech-niques. Annual salary range: Assistant $36,600 to$45,700. Please send inquiries and curriculum vitae to:

Dr. Paul I. TerasakiUCLA Tissue Typing Laboratory

1000 Veteran AvenueLos Angeles, CA 90024

UCLA is an Equal Oppunity AffirmativeActon Em-ployer.

ASSISTANT PROFESSOR/VETERINARY SCIENCE

The advertisement in the 1 January 1988 issue ofScenwc for this position at the University of AlaskaFairbanks induded the following statement: "Board cer-tification or eligibility in laboratory animal science orother speciality fields." Please note that this is a pre-ferred, not a required, qualification. Please see thatadverisement for other details.

PERSONNEL PLACEMENT 515

PersonnelPlacement

SCIENCE publishes each Friday, except the last Fridayof the year. Advertising is accepted only in writing; noabbreviations. Any deadline in ad must be at least 2weeks after date of issue in which ad appears. Also,personnel advertising is accepted only with the under-standing that the advertiser does not discriminateamong applicants on the basis of race, sex, religion,age, color, national origin, handicap, or sexual prefer-ence.

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ANNOUNCING A CONFERENCE ON:

RISK ASSESSMENT INAGRICULTURAL BIOTECHNOLOGY

July 31-August 4, 1988UNIVERSITY OF CALIFORNIA, DAVIS

DAVIS, CALIFORNIA

The conference will emphasize scientific prin-ciples applicable to assessing the risks ofproducts of biotechnology. Among the topicsto be discussed will be:

Developing applications of biotechnologyin agriculture; Metabolic, genetic, andecosystem limitations to spread and sur-vival of organisms; Types of risks relevantto biotechnology; Development of experi-mental protocols for monitoring orga-nisms; Quantification of impact on agro-ecosystems; Current and future directions.

The conference will include both invitedspeakers and contributed posters. For furtherinformation and registration brochure con-tact, after March 1, 1988: Donna Hyatt,Dean's Office, College of A&ES, University ofCalifornia, Davis, CA 95616, (916) 752-9485.

29 JANUARY I988

POSITIONS OPEN

ANATOMIST-UNIVERSITY OF CALIFOR-NIA, SAN DIEGO VISriING PROFESSOR posi-

tion open to teach gross anatomy at the UCSD School ofMedicine, Department of Surgery, Anatomy Division.Qualifications indude: Ph.D. in anatomy or M.D. withequivalent training; Professor-level experience in teach-ing medical students gross anatomy with a strong dinicalonentation; Established expertise as a teacher in theuniversity setting; Experience and ability in administra-tion within an academic setting. Four-month ayppoint-ment (September through December 1988). Salary de-pendent on qualifications. Closing date: 1 April 1988.Successful candidate may be reappointed in future years.Send curriculum vitae and names of three academicreferences to: Nicholas A. Halaz, M.D.; Deprtment

of Surgery, 225 Dicknson Street, San Diego, CA

92103.

ANATOMISTASSISTANT PROFESSOR

DEPARTMENT OFHUMAN ANATOMY AND PHYSIOLOGYThe Fairleigh S. Dickinson, Jr., College of Dental

Medicine, located on the Teaneck-Hackensack Campusof tri-campus Fairkeigh Dickinson University, has a fll-time, tenure-track position available for an assistantprofessor in the Department of Human Anatomy andPhysiology. Responsibilities indude teaching, researchand service in the dental and graduate programs.

Qualifications: Ph.D. in Human Anatomy (D.D.S.;D.M.D.; or M.D.); teaching experience in gross anato-my, neuroanatomy, histology, and embryology.Submit r6sumn and letter of application by 19 Febru-

ary to: airlgh Dickinson University, UnivtyEmployment Office, 1000 River Road, Teanck, NJ

07666.Women and minortie art enouraged to apply. FDU is

an Equal OpportuntylAffirmatieAction Eployer.

The Yale University Department of Neurology seeksan ASSISTANT PROFESSOR to conduct indepcn-dent research in magnetic rcsonance spectroscopy(MRS) of cerebral metabolism in vivo, with the goal ofobtaining new basic information about neurochemistryby application of new MRS methods. Expericnce with3iP, 3C andlH spctrosopy at the doctoral lcvel andknowledge of ncurochemistry are cssential, and a recordof publication in these arcas is highly desirable. Becausethe position is intended to promote basic rcscarch,neither clinical training nor experience with specificdiseasc-related problems is necessary. Yak Univna ys an

Affirmati ActiEqual Opprnity Employer. Pcrsonsinterested in the position should send curriculum vitae,bibliography, relevant reprints, and the names of twoprofessional references to: Professor James W. Prich-ard, Yale Medical School, 333 Cedar Steet, NewHaven, CT 06510 by 1 March 1988.

ASSISTANT PROFESSORMOLECULAR VIROLOGY

The Departments of Ophthalmology and Virology ofBaylor College of Medicinc seek an mnovative scientistto develop an independent research program on herpesvirus infections. Responsibilities also indude establishingand coordinatng a diagnostic ocular virology laboratory.Applicants for this tenure-track position at the assistantprofessor level should have a Ph.D. with at least 2 yearsof productive postdoctoral experience in virology re-search. Salary is commensurate with experience. Negotia-ble starting date. Send curriculum vitae, names ofat leastthree references, and a statement of research interests to:Dr. K R. Wilhelmus, Chairperson-Search Commit.tee for Molecular Virologist Position, Department of

Ophthalmology, Culkn ye Institute, Baylor Coilege

of Medicine, One Baylor Plaza (NC200), Houston,

TX 77030. Equal Opportunity Employer.

ASSISTANT/ASSOCIATE PROFESSOR. Full-time, tenure-track faculty position available 1 July 1988in the Degartment ofAnatomy. Position requires Ph.D.Lesponsibilitis uindudc teaching histolosy to undergrad-uate and gaduate dental students, and di dn gmuuatestudent eses. Record of research and a fundingdesirable. Salary and academic rank commensurate withexperience. Equal OpportunitylAffirmativ Acion Em-ployer. Send curriculum vitae to: Dr. Joseph M. Gow-giel, Chairman, Department of Anatomy, School ofDentstry, LOyola niersity ofChicago, 2160 SouthFirst Avenue, Maywood, IL 60153.

ASSISTANT PROFESSOROF

PHARMACOLOGY/TOXICOLOGYTenure-track faculty positions are availabk in the

Department of Pharmacology and Toxicolo$y at theMedical College of Georgia for individuals with strongpromise for research and teachingin modern pharmacol-

ogy or toxicology. Applicant should have a Ph.D. or

M.D. degree, significant postdoctoral research accom-

plishments, and the ability to respond to new challenges.Current strengths ofour department are in the cardiovas-cular and neuroscience areas. Appointoes are expected toestablish a strong research program and effectively edu-cate medical and graduate students. Please send curricu-lum vitae, bibliography, summary of professional goals,and names of three refercnces to: W. W. Caldwell,Department of Pharmacology and Toxicology, Medi-cal Coilege of Georgia,AgstaGA 30912. EqualOpportunity Emplyr/AffirateAction Program.

SCIENCE WORLD BRMSH COLUMBIAASSOCIATE DIRECTOR SCIENCE

The A.S.T.C. Science World Society, a private non-profit organization, is convcrting the ExpoCentre into a105,000-square-foot world class interactive science cen-tre.A scintist educator is sought to ensurc the quality and

accuracy of all aspects of the centre's scientifl7c content,displays and audio-visual presentations. This person willreport to the managing director, work with a tcam ofexperienced operations, design and marketing personneand coordinate the inputs of a number of scientistconsultants in the design program and be the centre'srepresentative in the scientific community.

Applicants should have a Ph.D. degree in a majorscientific discipline and experience as an educator atpublic school and/or college levels. Experience as ascience director in a scicnce centrc or a muscum settingwould be an advantage.

Please reply in writing stating availability and salaryexpectations to:

The A.S.T.C. Science World Society600 Granville StreetVancouver, B.C.

V6C 1Y9Attention: Mr. N. W. Fletcher, P. Eng.

Managing Director

ASSOCIATE ENVIRONMENTALHAZARDS SCIENTIST

The California Department of Food and Agriculturewill hold a competitive exam for positions in the Envi-ronmental Momtoring and Pest Management Branch

(Sacramento office). Requires MS. and 2 years of re-

search experience or a Ph.D. Starting salary: $32,400.Exam final filing date: 4 March 1988. Excellent benefits.Areas of expertise: analytical chenistr, statistics, mathe-matics/modeling, computer science, soil science, microbi-ology/statistics, planning/implementation. For an appli-

cation calwrite: John Sandes or Kathy B n ,

California Department of Food and A1220 North Street A-149, Sacramento, v 95814.Telephone: 916-324-8916 (leave name and address).

INSTITUTE OF CHEMICAL TOXICOLOGYWAYNE STATE UNIVERSITY

Wayne State University is pleased to announce thedevelopment of a new institute dedicated to research intoxicology. The Institute of Chemical Toxicology occu-

pies newly renovated laboratory space consisting of16,000 square feet within the Metropolitan Center forHigh Technology and featurcs moderm research andsupport facilities. Applications are invited for tenure-track faculty positions in the ranks of ASSISTANTPROFESSOR, ASSOCIATE PROFESSOR, andPROFESSOR in the areas of molecular, respiratory,and heavy metal toxicology. Emphasis will be accordedresearch which utilizes modem molecular and cellularapproaches in the investigation ofmechanism(s) ofxeno-biotic-mediated toxicity. Although initial emphasis isdirected toward the aforementioned areas of research,applications from outstanding candidates in other areasof contemporary toxicology will be considered. Candi-dates should have an M.D. or Ph.D. degree, at least 2years of relevant postdoctoral research experience, dem-onstrated productivity and be capable of conductingindependent research and securing cxtramural support.Salary and rank commensurate with qualifications.Curriculum vitae and three letters of reference should

be sent by 31 March 1988 to:

Dr. Raymond F. NovakChairman, Search Committee

Institute of Chemical ToxicologyWayne State University1072 Mackenzie HallDetroit, MI 48202

Wayne State Univerity is an Equal OpportunityAffir-mat Actin Employer.

New York University Department of Chemistry in-

vites applications for a tenure-track position in any ficldof organic chemistry at either the ASSISTANT ORASSOCIATE PROFESSOR level, to begin in the fallof 1988, pending final administration approval. Appli-cants should have a major commitment to conducting avigorous and innovative research program. The success-ful candidate will bc expected to be abk to teacheffectively at both the graduate and undergraduate levels.Applicants should submit curriculum vitac, with a list ofpublications, a summary of past research accomplish-ments, and an outline of proposed research interests, andshould arrange three letters of reference to bc sent, by 16February 1988 to be assured of fuUl consideration, to:NYU Faculty of Arts and Science, of

Chemistry, 4 Washington Place, 5th Floor, NewYork, NY 10003. Attention: Professor Alvin I. Ko-sas, Chair, Organic Search Committee. NYU iu an

Equal OpportunityAffirmativ Acto Eployer.

THE WHITEHEAD INSTlTUTE FORBIOMBEDICAL RESEARCH

AND THE DEPARTMENT OF BIOLOGY,MASSACHUSETTS INSITUTE OF

TECHNOLOGYASSISTANT OR ASSOCIATE PROFESSORS

Candidates are sought with significant experience in

the field of vertebrate developmental biology utilizing acombination of classical, genetic and molecular ap-proaches. Special attention will be given to applicantswho develop rescarch programs which focus on cell-cellinteraction, cell migration, cell commitment and celldifferentiation. Such candidates will be considered for a

joint, tenure-track, academic appointment between theWhitehead Institute for Biomedical Research and theDepartment ofBiology, Massachusetts Institute ofTech-nofogy. A candidate will be expected to conduct a

research prog in developmental biology and to par-ticipate in the Departments teaching activities. Appli-cants for these positions should provide curriculum vitae,a short description of their research plan, and names ofthree scientists willing to write letters of recommcnda-tion. Send applications to: Dr. RudolfJaenisch, White-head Institute, 9 Cambridge Center, Cambridge,MA02142. AffirmativeActionEqual Opporunity Employer.

SCIENCE, 239

ASSISTANT/ASSOCIATE PROFESSOR(tenure-track), Department of Medicinc, Stan-ford. The Division of Oncology of StanfordUniversity is scarching for a full-time facultymember for its filly integrated program at thePalo Alto Veterans Administration Medical Cen-ter. Candidates should be fully qualified in medi-cal oncology, and have demonstrated or have thepotential for an independent clinical researchprogram rclevant to oncology. Excellent supportand facilitics are available. This tenure-line ap-pointmcnt will be at the assistant or associateprofessor level. Send resume, including bibliog-raphy, and summary of research goals to: FrankM. Torti, M.D., Assocate Professor ofMedi-cine, Department ofMedicine (H), Palo AltoVeterans Administration Medical Center,Palo Alto, CA 94304. Stanford Universty iscommitted to crea jreprsa of womenand members ofminonty groups on its fculty andpariulay encourages applcatifom such candi-da.

POSITIONS OPEN POSITIONS OPEN

POSITIONS OPEN

ASSOCIATE PROFESSOROR PROFESSOR

ENVIRONMENTAL HEALTH SCIENCE

A faculty member with multidisciplinary interests isbeing sought to provide leadership for the Environmen-tal Health Sciences Division of the Department of Envi-ronmental and Industrial Health in the School of PublicHealth. This division has 9 faculty and 85 graduatestudents. Responsibilities: guide, integrate and partici-pate in the interdisciplinary research and instructionalactivities of this group. Qualifications: national recogni-tion for sustained research program and major scholarlycontributions in an environmental health related area,demonstrated effectiveness in teaching, proven leadershipabilities for a multidisciplinary group, demonstratedresearch strengths in one or more areas ofenvironmentalhealth. Applicants should send statement of researchinterests, curriculum vitae, and names of three referencesto: Robert H. Gray, Ph.D., Chairman, Department ofEnvironmental and Industrial Health, The UniversityofMichigan, 109 South Observatory, Ann Arbor, MI48109-2029. The Univesity ofMichwgan is an Affirma-tive ActionlEqual Opportunity Employer and specificallyencourages applicationsfrom womcn and members ofminoritygroups.

BIOLOGY. TENURE-TRACK POSITION be-ginning fall semester 1988 as the Coordinator ofLabora-tories in College Biology I and II (course approvalpending), the introductory course required of all majorsin the biological sciences (biology, zoologv). In addition,the appointee will teach in those laboratories, possiblyserve as one of the lecturers in that course, and teachadvanced courses which must include comparative verte-brate anatomy. Ph.D. required. Women and minorities areencouraged to apply. Send letter, curriculum vitae, threeletters of reference, transcripts, and a statement of re-search interests by 22 February 1988 to: Dr. Sigurd O.Nelson, Jr., Chair, Department of Biology, StateUniversity ofNew York College at Oswego, Oswego,NY 13126.

An Equal Opportunity Employer

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ASSOCIATE/FULL PROFESSOR, InternationalNutrition. The Department of Nutrition, University ofCalifomia, Davis, is seeking applicants for an 11-monthtenure-track faculty position at the level of associate orfull professor in nutrition and associate or full nutrition-ist in the Experiment Station to begin 1 January 1989.The appointee will have responsibilty for developmentand expansion of a Program in International Nutrition.It is expected that the appointee will organize andconduct independent research in his/her disciplinary area,and have the ability to acquire extramural funding.Expertise in an area of hunan nutrition is essential. Theappointee will also teach at the graduate and undergradu-ate levels and serve as adviser to undergraduate andgraduate students. Interested persons should send acomplete biography, a statement ofresearch and teachinginterests, copies of selected publications, and the narnesand addresses of three references to: Dr. Andrew J.Clifford, Deptent ofNutrition, University of Cal-ifornia, Davis, CA 95616. The University ofCal#fornia isanAffimtiveActionlEqual Opportunity Employer and willwelcomc appliations from members of minoity fgrops andwomen. Applications will be received until 31 March1988 or until the position is filled.

DIRECTORDirector, Agricultural Biotechnology Center, Marv-

land Biotechnology Institute. The position is located atCollege Park, Maryland and involves the direction ofrescarch in development and application of modernbiotechnology to benefit agriculture and related sciences.An earned doctorate in agriculture and life science area,tenurable, proven research and external support record,and leadership, and organizational skills required. Quali-fied individuals submit a letter of application and adetailed resume including names, addresses, and tele-phone numbers of three references who may be contact-ed to: A. L. Steinhauer, Chairman, Search Committeefor ABC Director, Department of Entomology, Uni-versity of Maryland, College Park, MD 20742. Com-lete application should be received by 29 February 1988

For fil consideration. The University ofMaryland is anAffirmativeActionlEqual Opportunity Employer.

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BIOCHEMIST/CHEMIST: Assistant professor(non-tenure)/instructor/postdoctoral fellow to join largeneuroscience lab with interest in purification and charac-terization of novel bioactive materials. Experience inanalytic, enzyme, peptide chemistry or second messengersystems desirable. Strong interaction with molecular andcell biologists. Send curriculum vitae and bibliographyto: D. J. Reis, Laboratory of Neurobiology, Corne lUniversity Medical College, 411 East 69th Street,NY, NY 10021. Equal Opportunity EmployerlAffirmativeAction/M/F/HIV.

BIOLOGIST (VERTEBRATE ZOOLOGIST/PHYSIOLOGIST). Northern State College is seekingqualified applicants for a tenure-track position as assist-ant professor of biology. Responsibilities include teach-ing introductory level lecture and laboratory courses aswell as upper-level courses in areas of expertness. Ph.D.with background in vertebrate zoology/physiology pre-ferred. Position available 15 August 1988. Address nom-inations and applications to: Dr. Thomas Flickema,Vice President for Academic Affairs, Northern State,Aberdeen, SD 57401. Consideration of applicationswill begin on 1 March 1988 and will continue until theposition is filled. Equal Opportunity Employer.

CELL BIOLOGIST/HISTOLOGISTCORNELL UNIVERSITY

The Section of Physiology is seeking an assistantprofessor (tenure-track) to teach an upper-level course(histology/organology) emphasizing the relation be-twecn structure and function at the tissue and organlevel. The successful applicant is expected to develop astrong research program in some aspect of animal cellbiology. Applicants should hold a Ph.D., M.D., D.V.M.,or equivalent degree and have postdoctoral experience.Submit curriculum vitae, list of-publications, the namesand addresses of three references, and statements ofteaching experience and research interests by 1 March1988 to: Dr. Ellis R. Loew, Chair, Search Committee,Section of Physiology, VRT 724, Cornell University,Ithaca, NY 14853. Cornell University is an AffirmativeActionlEqual Opportunity Employcr.

The Drug Metabolism Department of Smith Kline & French Laboratories, locatednear Valley Forge, PA, has an excellent opportunity available for a Scientist.The successful candidate will:* assist in the design, conduct and reporting of Drug Metabolism studies

involving animals.* develop and perform assays for drugs and their metabolites in

biological fluids.* conduct pharmacokinetic studies in animals.* participate in basic research activities in drug metabolism designed to assist

in drug development and drug discovery.* write reports and manuscripts for publication.Candidate specifications include:* B.S. degree with 3-5 years experience or M.S. degree in Chemistry, Biological

Sciences or related area plus 1-2 years experience required.* Demonstrated experience in bioanalytical methods development (e.g. HPLC)

for drugs in biological fluids required.* Extensive experience of administering drugs and obtaining biological samples

from animals required.* Experience in the isolation, purification and characterization of metabolites

from biological fluid preferred.* Proven research ability as evidenced by scientific publication desirable.* Research experience in drug metabolism/pharmacokinetics useful.* Excellent communication and interpersonal skills required.* Experience in handling radio-labeled substances desirable, but not essential.* No known allergies to animals.We offer an excellent compensation, benefits and relocation package as well asopportunities for personal and professional growth. For confidential considera-tion please forward your C.V. and names of three references to MarianneShandy, Manager, Personnel Relations-R&D, C0070, Smith Kline & FrenchLaboratories, P.O. Box 1539, King of Prussia, PA 19406-0939. We are an equalopportunity employer. M/F/H/V.

[=_%O Payment enclosed O Bill me later I

POSITIONS OPEN POSITIONS OPEN

POSITIONS OPEN

BIOLOGY-Tenure-track ASSISTANT PROFES-SOR. Appropriate earned doctorate required. Dutiesinclude teaching histology, anatomy and physiology andgeneral biology. Appointment date: 1 September 1988.Send letter, curriculum vitae, official academic tran-scripts, statement ofteaching interests and three letters ofreference by 15 March 1988 to: Dr. Charles Chapman,Department of Biological Sciences, Troy State Uni-versity, Troy, AL 36082. TSU is an Affirmative ActionlEqual Opportunity Employcr.

DEVELOPMENTAL BIOLOGISTASSISTANT PROFESSOR

Broadly trained developmental biologist withstrengths at the molecular 1evel to teach courses inmodem developmental cell biology to undergraduates.Ph.D. required. Postdoctoral experience desirable. TEMexperience usefil, but not required. Faculty are expectedto conduct active research programs in which qualifiedundergraduates may be involved. Start up funds forresearch are provided. Position available 1 July 1988.Please send curriculum vitae, statement of research/teaching interests, and names and addresses of threereferences by 19 February 1988 to: Chair, Departmentof Biology, Williams College, Williamstown, MA01267.AnEqual OpportunitylAffimtiveActionEmployer. Wil-

hlam College especially wekomes applications from womenand minority candidates.

THE NEW YORK BLOOD CENTER is the larg-est independent blood center in the world and a majorfractionator of plasma. Recent reorganization and expan-sion of research and development ventures have createdscveral opportunities in our Research and DevelopmentDepartment. Research emphasis is on therapeutic deriva-tives from blood and lymphokine biology.DIRECTOR-Dcpartment head with Ph.D., strong

leadership and research credentials in protein biochemis-try, separations, etc. Individual will participate in select-ing targets and have chief responsibility for the labora-tories and pilot plant.ASSISTANT/ASSOCIATE DIRECTOR-Ph.D.

to lead research related to fibronectin growth promotersand wound healing.RESEARCH FELLOW-Ph.D. to participate in

devising and evaluating virus sterilization methods appli-cable to blood cell components. Experience in virologyrequired.

Please submit resume, position interest and currentsalary to: BH, The New York Blood Center, Atten-tion: Personnel, 310 East 67th Street, New York, NY10021.

Equal Opportunity Employer

EVOLUTIONARY GENETICISTThe Department of Zoology, Arizona State Universi-

ty, invites applications for a tenure-track position at theassistant professor level. Starting date for the position is15 August 1988. Individuals with accomplishments andinterests in molecular genetics, population genetics andthe evolution of genetic systems m natural populationsare encouraged to apply. Salary is dependent uponqualifications. Submit curriculum vitae, reprints, state-ments of research and teaching interests, and three lettersof references to: Dr. David I. Rasmussen, Chair,Faculty Search Committee, Department of Zoology,Arizona State University, Tempe, AZ 85287-1561.Deadline for receipt of application material follows by 4weeks the date of this issue.The Department accepts applications of two individ-

uals for a single shared appointment. Anzona StateUniversty is an Equal OpportunitylAffirmative Action Em-ployer and invites and encourages applications from womenand minorities.

FACULTY APPOINTMENT at assistant or asso-ciate professor level; Ph.D. in statistics or biostatisticsrequired. Responsibilities will consist primarily of re-search and consulting, but will also include some gradu-ate teaching. Opportunities exist for collaborative workwith both clinical and basic science researchers. Sendcurriculum vitae and names of three references to:Charles DeLisi, Ph.D., Chairperson, Department ofBiomathematical Sciences, Mount Sinai School ofMedicine, Box 1023, One Gustave L. Levy Place,New York, NY 10029-6574. An Equal OpportunityEmployer.

5i8

THE UNIVERSITY OF NORTH CAROLINADIRECTOR

THE INSTITUTE OF NUTRITIONThe University of North Carolina is seeking a new

Director for its Institute of Nutrition. The Institute is amultidisciplinary and inter-campus unit organized toassist faculty in their educational, research and communi-cation efforts related to the nutritional well-being ofNorth Carolinians. Presently, there are five campuses:East Carolina University, North Carolina Agriculturaland Technical State University, North Carolina StateUniversity, University of Nor Carolina-Chapel Hill,and University of North Carolina-Greensboro. TheDirector reports to the University's Vice-President forResearch.

Responsibilities: Provide leadership in promoting andfacilitating nutrition projects and programs among thefive universities; promote special nutrition educationprograms; assist in obtaining external research fundingfor cooperative activities of the participating institutionsand faculty; and encourage development of collaborativenutrition programs among the University disciplines andnon-University organizations.

Qualifications:* Eamed doctorate in nutrition or a closely associated

discipline; experience appropriate to qualify for appoint-ment at the academic rank of Professor.* Record of professional activities, research and schol-

arship which establishes preeminence at the national/intemational level.* Possession ofthe requisite administrative and leader-

ship skills for the management of interdisciplinary andinter-institutional programs.

Faculty status and salary: Academic appointment willbe at one of the participating universities, salary com-mensurate with experience and qualifications.

Applications will be accepted until 1 April 1988 oruntila suitable candidate is identified. Expected startingdate is Fall, 1988.

Application: Send resume and names of three refer-ences to:

Dr. Ernest Schoenfeld, ChairSearch Committee

The Institute of NutritionCB #7410 311 Pittsboro StreetUniversity of North CarolinaChapel Hlll, NC 27599-7410

FACULTY POSITION INDEVELOPMENTAL BIOLOGY

The Department ofAnatomy and Cell Biology invitesapplications for a tenure-track faculty position. Appli-cants should have a strong training in developmentalbiology, induding postdoctoral studies, with an orienta-tion toward the nervous system. Successful candidate willbe expected to participate in the campus-wide Neurosci-ence Committee actvities and in the neuroanatomycourse, and develop an independent, funded researchprogram. Recruitment will continue until the candidateis identified. Please send a description of research inter-ests, curriculum vitae, and the names of three referencesbefore 15 March 1988 to: Dr. C. H. Anderson, SearchCommittee, Deparment ofAnatomy and Cell Biolo-gy (m/c 512), Univcrsity of Illinois at Chicago, P.O.Box 698, Chicago, IL 60680. The UIC is an EqualOpportunitylAffirnative Action Employer.

The Department of Biochemistry at Eastern VirginiaMedical School has several open FACULTY POSI-TIONS for outstanding candidates at the level of assist-ant or associate professor. These are tenure-track posi-tions with competitive 12-month salaries and provideexcellent opportunities for independent research pro-grams and teaching. Successful applicants will develop astrong research program in an area ofmodern biochemis-try or molecular biology such as the mechanism of generegulation, DNA-protem interactions, metabolic regula-tion, enzyme mechanism, or hormone receptors andtransmembrane signaling. Faculty members will be ex-pected to attract independent research grants and tospend a major part of their effort in research.

Please send curriculum vitae, a statement of researchinterests and plans and three letters of reference to: Dr.Karl A Schellenberg, Chairman, Department of Bio-hemistry, Eastern Virginia Medical School, 700 01-ny Road, Norfolk, VA 23501.

DIRECTORDIABETES RESEARCH INSTUTE

Eastern Virginia Medical School invites applicationsand nominations for the position, Director, DiabetesResearch Institute. The Diabetes Research Institute ispart of a comprehensive regional diabetes center that alsomcludes clinical and educational components. The Insti-tute has already received substantial initial supportthrough an aggressive local and national fund-raisingeffort. The successful candidate will possess an extensiveacademic background, an established record ofexcellencein diabetes research and the skill, capacity, and entrepre-neurial instinct to assure the long-term success of theResearch Institute. Responsibilities of the position in-dude developing a research program that will makesignificant contributions to the field of diabetes as well asdirecting research projects, program administration, andoutreach. Full faculty status and benefits are available;conditions and salary are negotiable. Please reply to:

Leon P. Georges, M.D.Acting Center Director

The Diabetes Center of Eastern VirginiaP.O. Box 1980

Norfolk, VA 23501

FACULTY POSMIION-HEMATOLOGYFull-time tenure-track position at assistant or associate

professor level available. Applicants must be Board-certified or eligible in hematology, and have appropriateresearch training and a strong commitment to or estab-lished record in basic or clinical research, preferablyrelated to hemostasis and thrombosis or atherosclerosis.Ample laboratory space available. Interested candidatesshould send curriculum vitae, a description of researchinterests, and names of three references to: J. H. Joist,M.D., Ph.D., Division of Hematology, St. LouisUniversity Medical Center, 1325 South Grand Bou-levard, St. Louis, MO 63104. Equal Opportunity Em-plyer, M/FIHIV.

New York University (NYU) Department of Chemis-try invites applications for a tenure-track FACULTYPOSMON IN THEORETICAL CHEMISTRY ateither a tenure or non-tenure level, beginning in fall1988, pending final administrative approval. Applicantsprovide evidence of a major commitment to research.The successful candidate will be expected to be able toteach effectively at both the undergraduate and graduatelevels. Applicants should submit curriculum vitae, with alist of publications, a summary of past research accom-plishments and arrange for three letters of reference, tobe sent by 16 February 1988, to assure full considerationto: NYU Faculty of Arts and Science, Department ofChemistry, 4 Washington Place, 5th Floor, NewYork, NY 10003. Attention: Professor JulesMoskowitz, Chair, Faculty Search Committee. NYUis an Equal OpportunitylAffimativc Action Employer.

FACULTY POSITION-NEONATOLOGY. Ap-plications invited for Neonatal-Perinatal Board-certified,assistant professor, starting July 1988. Applicant musthave training and experience in vascular cell biologmolecular physiology and free radical chemistry, in addi-tion to strong clinical skills. Submit curriculum vitae andnames of three references to: Box 15, SCIENCE.

FACULTY POSITIONS, TOXICOLOGYApplications are invited for two tenure-track assistant

professor positions in the toxicology program of 13faculty at the University of Michigan. Candidates musthave a doctorate in a relevant biomedical field, postdoc-toral research experience complementary to current facul-ty interests of cutaneous, endocrine-reproductive, genet-ic, and neurotoxicology, the biotransformation of toxi-cants, chemical carcinogenesis-mutagenesis, and toxico-logic pathology. Candidates must also have demon-strated potential for obtaining research funding fromnational sources, documented excellence in teaching, anda commitment to toxicology. Applicants are to submitcurriculum vitae and names of three references to: Wal-ter N. Piper, Ph.D., Chairman, Toxicology SearchCommittee, The University of Michigan, 109South Observatory, Ann Arbor, MI 48109-2029.Applications will be accepted until 15 March 1988. TheUniverity of Michan uS an Affirmtive Action/EqualOpportynt Employer, and encourages women and minor-ities to apply.

SCIENCE, VOL. 239

POSITIONS OPEN POSITIONS OPEN

POSTDOCTORALFELLOW

Position available in the Department of Biochem-istry & Molecular Biology for investigation of thestructure-function relationships of G-protein-linkedreceptors. The project will focus on the molecularmechanisms of B-adrenergic receptor action, inconjunction with biophysical characterization of aseries of mutant B-receptors.The successful candidate will have a Ph.D. with astrong background in biochemistry or biophysics,with demonstrated interest in the mechanisms ofprotein action. Experience in reconstitution orbiophysical characterization of membrane proteinsis desirable.Merck Sharp & Dohme Research Laboratories arelocated in Rahway, New Jersey approximately 25miles from New York City. Our salaries, benefits,and growth potential are excellent.Interested candidates should submit their resumewith the names of three references and salary re-quirements to: Ms. Jacqueline A. Eiermann, Merck &Co., Inc., P.Q Box 2000, Rahway, New Jersey 07065.

Equal Opportunity Employer

ADVERTISEMENT

POSITION: Assistant or Acting Associate Specialist in the Division of BiologicalControl, University of California at Berkeley, stationed at the Kearney AgriculturalCenter, Parlier, California. Available 1 April, 1988.

MINIMUM QUALIFICATIONS: Ph.D. degree in entomology or pest managementwith at least one year of experience in biological control of insect and mite pests.

Experience in culturing, colonization, and evaluation of natural enemies is highlydesirable. Candidates should be conversant in modern statistical methods.

RESPONSIBILITIES: Conduct research in biological control of agriculturalarthropod pests: develop programs in classical biological control and inaugmentation and conservation of natural enemies; evaluate impact of biologicalcontrol agents; manage quarantine facilities.

Interact with other researchers in developing protection programs for crops suchas alfalfa, citrus, deciduous fruits and nuts, olives, sugar beet and others ofimportance to California agriculture.

Supervision of technical staff as needed.

The Kearney Agricultural Center is located in Parlier, approximately 25 mi.southwest of Fresno, a city with a population of approximately 300,000. It isstaffed by 22 scientists from the Berkeley, Davis and Riverside campuses andfrom Cooperative Extension. Disciplines such as Entomology, Plant Pathology,Nematology, Pomology, Viticulture, Vegetable Crops, Water and Soil Science,Livestock, Agricultural Economics, Horticulture, and Extension Education arerepresented in the Center. Approximately 330 acres of land for researchexperimentation are part of the Center. All the facilities necessary to conductresearch in biological control and crop protection, such as quarantine facility,greenhouses, laboratories and computer center, are available.

Bibliography, including all employment in entomology and pest management,and names of three individuals who would serve as references should be sent to:

Donald L. Dahisten, ChairDivision of Biological Control

University of Califomia, Berkeley 94720

Closing Date: 1 March, 1988

The University of California is an Equal Opportunity, Affirmative Action employer.

THE AGA KHAN UNIVERSITYFwulty o1 Health Sie

Mr&, Come

The Aga Khan Medical College is now in its fifth year of operation. Itsaffiliated Aga Khan University Hospital has well equipped teaching andservice laboratories and will have 721 beds when fullv operational. TheUniversity and the University Hospital are autonomoua privatelv fundedinstitutions respectivelv committed to the provision of effective educationand health service relevant to Pakistan and the region.

Applications are invited from candidates who meet the requirementi forthe positions of:

ASSISTANT PROFESSOR,DEPARTMENT OF BIOCHEMISTRYCandidates appiving for this position must have a Ph. D. or equivalentqualification, with at least two vears Post-doctoral teaching/researchexperience. Candidatesi having experience of teaching in a Medical Collegeor involved in medical research will be given preference. The surcesfiulcandidate will he requsired to participate in ongoing researchprogrammes.INSTRUC1TOR,DEPARTMENT OF BIOCHEMISTRYC-andidates applying for this position must have M. PhiL or Ph.D. withone year of experience. Candidates having both M.B.B.S. and Ph.D. will bepreferred.

Salary and benefits will be offered commensurate with qualifications.experience and level of responsihilities. Candidates intending to ptursue acareer in Pakistan will be preferred. If you meet the abot-e requirementsand are seeking career de%elopment and professional growth, please sendyour detailed resumn. bibliographv and names of at least three refereesfamiliar with recent work historv to the Personnel Director, The AgaKhan University. P.O. Box 3500. Stadium Road. Karachi-5. Pakistan.

ImmunoanalyticalChemistThe Procter & Gamble Company is seeking an individual withexperience in the development and application of immuno-assay(RR EUSA) techniques for the measurement ofanaytesin biological matrices. This individual should have Ph.D. orpostdoctoral training in analytcal chemistry, clinical chemistry,biochemistry, or immunology. The position is at the MiamiValley Laboratories in Cincinnati, Ohio.Responsibilities will include the supervision of a divisionalimmunoasssay/ligand binding laoratoryasw1t as thedevepment of assay systems for novel drug candidates and endo-genous species of pharmaceutical interest. Backgroundexperience in poly/monoclonal antibody production and puri-fication, hapten-carrier conjugation, and enzymatic/isotopiclabeling is highly desired.Good communication skills and research experience in aninterdisciplinary team environment are also important candi-date requirements.Applicants must be U.S. cifizens or posses a permanent resi-dentvisa and should send their resume and publication list to:

Dr. T. J. Logan, ManagerPh.D. RecruitingImmunoanatical Chemist PositionThe Procter & Gamble CompanyMiami Valley LaboratoriesRO. Box 398707, Cincinnati, Ohio 45239-8707

Procrer & GambleAN EQUAL OPPORTUNITY EMPLOYER NOAGENCY REFERRALSL'4

NMIIIIIIIIllh.,

iiiiiiiiiiiiiiiiiw

POSITIONS OPEN

FACULTY POSITIONPHARMACOLOGY AND TOXICOLOGY

UNIVERSITY OF OKLAHOMACOLLEGE OF PHARMACY

The University of Oklahoma College of Pharmacyannounces an immediate opening for a tenure-trackposition at the assistant professor level in the area ofpharmacology and toxicology. Postdoctoral training inpharmacology/toxicology is highly desirable. The suc-cessful candidate will be expected to participate in anddevelop courses in pharmacology/toxicology at the un-dergraduate and graduate levels and develop an indepen-dent, extramurally-funded research program. The Col-lege of Pharmacy is a new building located on theUniversity of Oklahoma Health Sciences Center (HSC)campus with Colleges of Medicine, Dentistry, Nursing,Allied Health and Public Health. Excellent laboratoryand animal facilities are located within the College.Opportunities exist for joint appointment in other HSCColclges. The salary is negotiable based on qualificationsand experience. Send curriculum vitae, a description ofresearch interests and goals, and the names of at leastthree references by 18 March 1988 to: J. Thomas Pento,Ph.D., Head, Division of Medicinal Chemistry andPharmacodynamics, College of Pharmacy, Universityof Oklahoma, Oklahoma City, OK 73190.

The Univenity of Oklahoma is an Equal OpportunitylAffirmatii Acaion Employer.

GRADUATE RESEARCH ASSISTANTSHIPAND POSTDOCTORAL ASSOCIATESHIPS avail-able through the Metabolism Training Program at CaseWestern Reserve University. Theprogram is directed byan interdisciplinary group of faculy in the Departments

of Biochemistry, Medicine, Pediatrics, Pharmacology

Molecular Biology, and Physiology and Biophysics and

fostcrs innovative interdisciplinary research emphasizingnew approaches to mctabolism, especially molecular biol-

ogy and biophysics. Doctoral programs are availablehrough the department listed above. Competitive sti-

pends. The program is partilwarly interested in recruitingminonty appliants. Interested candidates are invited toapply to: Dr. Richard W. Hanson, Program Director,Department of Biochemistry, Case Western RcserveUmversity School of Medicine, Clevdland, OH44106.

Equal OpportunitylAffirmativcAction Employcr.

INVERTEBRATE ZOOLOGIST

Tenure-track position at the assistant professor levelbeginning August 1988. Ph.D. required. Research inter-ests involving aquatic invertebrates, preferably marine.Teaching responsibilities in general and invertebratezoology, plus possibly a specialty course in area ofinterest. Expected to maintain externally funded activeresearch program. Postdoctoral experience preferred.Consideration of applications will begin 15 February1988 and continue until the position is filled. Send letterof aplication with teaching and research interests, cur-riculum vitae, official transcripts, and three letters ofrecommendation to: Dr. Chlord B. Knight, BiologySearch Committee Chairperson, Department ofBiO-ogy, East Carolina University, Greenville, NC278585-4353. Salary commensurate with experience.

Federal law requires proper documentation of identityand employability.East CaWolina Univensty is an Affirmative ActionlEqual

Emplymcnt Opptunity Employer, and encourages app1ica-tions from qualsfid women and minorities.

JUNIOR OR SENIOR POSTDOCTORAIRE-SEARCH ASSOCIATE position available to study theeffects of alcohol on the developing brain in an animalmodel system of Fetal Alcohol Syndome Neurosciencetraining with experience with computers and statisticalanalysis required. Preference will be given to those withdemonstrated expertise in receptor binding localizationand/or neuropharmacology. Have curriculum vitae andthree letters of recommendation sent to:

Dr. James R WestAlcohol and Brain Research Laboratory

The University of Iowa College of MedicineDepartment ofAnatomy, BSB

Iowa City, IA 52242The Univerity ofIowa is an Equal OpportunitylAffirma-

tiv Action Employer.

MALACOLOGISTApplications are invited for a research position in

systematic malacolosy with specialization in land snails.This position is initially funded for 3 years, with a highprobability of continued funding. Doctorate degree isrequired. Criteria for selection will indude demonstratedcapability in research, experience with collections, andproven record or potential for grantsnanship. BishopMuseum's holdings incude more than 6 million molluskspecimens. Two-thirds of these are terrestrial mollusksand comprise the world's largest and most completecollection of Pacific Island land snails. Prior researchexperience with the Pacific region is advantageous but isnot required; eventual specialization in the fauna of thisregion will be expected. Review of applications willbegin 1 February 1988; the position wil remain openuntil filled. Send letter of application, curriculum vitae,outline of research interests, and names of three refer-ences to: Dr. Allen Allison, Chair, MalacologistSearch Committee, Bishop Musm, P.O. Box

19000-A, Honolulu, HI 96817-0916. Telephone:808-848-4145. An Equal Opportunity Employer.

MICROBIOLOGY-Full-time position, RE-SEARCH TECHNICIAN IV, available immediately.

Salary $20,820 per year. Requires B.S. degree-hemis-

try-biology, and 1 year of expenence in hybridoma

research. Work involves production and characterization

of monoclonal antibodies. Contact: Dr. Robert Cher-niak at 404-651-3125 for additional information. Geor-gia State Univeity, a unit of the Uniity System ofGeogia, is an EqualEdcationalandEmploynet Opportu-nit Institution.

MOLECULAR NEUROBIOLOGY POSTDOC-TORAL FELLOW to join a group studying develop-ment of the nervous system. Dr. Marcus Jacobson,Anatomy Department, University of Utah School ofMedic, Salt Lake City, UT 84132. The Univeist ofUtab itS an Equal Opportunity Employer.

MARINE ECOLOGYThe Alabama Marine Environmental Sciences Consor-

tium (MESC) announces two faculty positions at theASSISTANT/ASSOCIATE PROFESSOR levels anda 2-year POSTDOCTORAL FELLOWSHIP in fish-eries to complement an expanding program in estuarineand shelf ecology. Applicants with expertise in popula-tion dynamics and production of larval fish and she lsh(especially decapod crustaceans), animal-substrate inter-actions, benthic/pelagic coupling, and nutrient dynamicsare especially sought, but strong candidates from otherspecialties will be given consideration.

Successful applicants will have a proven record of re-search producuvity with adem ated ability or pontialto attract eramural funding. Teaching responsibilities forfaculty normally indude two coursCs per year (on thequarter system). Salaries are for 12 months (postdoctoraltIllo) and 9 months (pm t faculty), and are compet-itive. A joint tenure-tra intnt at a Consortiummember university is stronlyen a and may becoordinaedi through the MESC adminisrtoMESC is an independent agency of Alabama Higher

Education housdf at the Dauphin Island Sea Lab, a 36-acre campus with office, laboratory, library and dormi-tory facilities. Courses are taught year round, with asummer program of nearly 100 undergraduate and grad-uate students in residence. MESC operates the 65' RJVA. E. Verrill as well as several smaler vessels. A newlyinstallcd 4000+ gallon seawater system is available.Applications with the names and addresses of threereferences should be sent by 1 March 1988 to:

Dr. Kenneth L. Heck, Jr.Marine Environmental Sciences Consortium

P.O. Box 369Dauphin Island, AL 36528

MICROBIOLOGIST. Northern State College issecking a qualified applicant for a tenure-track position asassistant professor of microbiology. Responsibilities in-clude teach medical microbiology and immunology aswell as introductory level lecturc and laboratory courses.Successful candidate will have a Ph.D. in microbiology.The position is available 1 August 1988. Address nomi-nations and applications to: Dr. Thomas Flickema, VicePresident for Academic Affairs, Northern State, Ab-erdeen, SD 57401. Consideration of applications willbegin on 15 February 1988 and will continue untilposition is filled. Equal Opporeunity E alyer.

MOLECULAR BIOLOGYCELL PHYSIOLOGY

DEPARTMENT OF BIOLOGYThe Department of Biology invites applications for

two tenure-track positions at the assistant professor levelto begin during the 1988 to 1989 academic year. Oneposition is in cell physiology and the other, in gencticsand molecular biology. The applicants are expected tohave postdoctoral experience. The department has stronginterests in experimental biology. This indudes facultyand graduate research in neuroscience, physiology, bio-chemistry and developmental, molecular and cell biolo-gy, and gcnetics. The appointee is epected to maintainan independent research program and contribute tograduate and undergraduate education. Interaction be-tween faculty at both the teaching and research levels isencouraged. Please send curriculum vitae, copies ofrepresentative publications, a suunary of previous andproposed research, and the names and addresses of threcreferences to: Dr. Ralph ilman, Chairman, Depart-ment of Biology, 015-00, Temple University, Phila-delphia, PA 19122. Closing date for applicaton is 30April 1988. Applications wilibereviewed upon receipt.Tempk Univenty is an Equal Opportunity/Affiratv

Acion Employff.MOLECULAR GENETICIST

Children's Hospital and Health Center is interested inrecruiting a junior faculty level molecular geneticist tomanage its Molecular Diagnosis Laboratory and to con-duct independent research.

Applicants should have M.D. or Ph.D. degrees andrecent experience in methods of molecular genetics.Clinical experience is desirable but not essential.To apply, send curriculum vitae, list of publications and

two letters of reference to: Deana Pilak, Human Re-source ChWrWs Hospital and HealthCsnter, F Sutr San Digo, CA 92123. Foradditional infornation, call: Dr. J. T. Masrello at 619-576-5809.An Equal Oppotunity Emplyer.

SCIENCE, VOL. 239

HEAD, DEPARTMENT OFBIOCHEMISTRYAND DIRECTOR

CENTER FOR BIOLOGICALCHEMISTRY

UNIVERSITY OF NEBRASKA-LINCOLN (UNL)

Applications, nominations, and inquiries areinvited for the dual-position of Head of theDepartment of Biochemistry and Director oftheUnversity-wide Center for Biological Chemis-try. The Department is part of the Institute ofAgriculture and Natural Resources and has astate- and federally funded research mission inthe Nebraska Agricultural Research Division.The undergraduate and graduate teaching pro-grams in biochemistry are administered by thenewly created Center and are offered in theCollege of Arts & Sciences and the College ofAgriculture.

Responsibilities include the dynamic and in-novative leadership of biochemistry programs atUNL by administering and participating in theresearch mission of the Department of Biochem-istry and directing the undergraduate and gradu-ate teaching programs of the Center for Biologi-cal Chemistry. Appointment will be at the fullprofessor level; sakary is comp*titve and basedon qualifications and experience. A Ph.D. or theequivalent is required, as are an outstandingbiochemical research record, proven interest andexperience in teaching biochemistry, and strongleadership ability and administrative potential.

Applications, nominations, and inquiriesshould be directed as shown below. Applicantsshould provide curriculum vitae and names, ad-dresses, and telephone numbers of at least dtreereferences by 15 March 1988 to:

Dr. Raymond CholletChair, Biochemistry Search Committee

210 Biochemistry HailUniversity of Nebraska-Lincoln

Lincoln, NE 68583-0718Telephone: 402-472-2936 or 472-2932

AffimativeActionlEqual Opportunity Employer

520

POSITIONS OPEN POSITIONS OPEN

BIOCHEMISTS/MOLECULAR BIOLOGISTSUNITED STATES BIOCHEMICAL CORP

United States Biochemical Corporation, aleader in the field of molecular biology hasimmediate openings for biochemists/molecularbiologists with experience and training inenzyme purification, DNA sequencing andanalysis. Various positions require either aPh.D., M.S. orB.S. degree in chemistry, biologyor biochemistry with at least 1 year's laboratoryexperience.

BIOCHEMISTSQualified candidates will be familiar with en-zyme and protein purification including suchtechniques as column chromatography, saltfractionation, gel electrophoresis and radio-active and spectrophotometric enzyme assay-ing procedures.

MOLECULAR BIOLOGISTSQualified candidates will be familar with DNAsequencing methods. This includes preparationof DNA and running sequencing electrophoresisgel apparatus.Successful applicants will be employed at ourwell-equipped Research Center in suburbanCleveland. Interested and qualified personsshould send their resume in confidence to:

United StatesBiochemical CorporationResearch CenterP.O. Box 22400Cleveland, Ohio 44122Equal Opportunity Employer MIF

University of California, DavisCELLULAR NEUROBIOLOGY

TRAINING PROGRAMFunding is available to support qualified indi-

viduals for training in cellular neurobiology atboth postdoctoral and predoctoral levels. Suc-cessful applicants will join a young, vigorousneurobiology group that is highly interactiveand in which collaborations are common. Weparticularly encourage participation of traineesin projects involving the expertise of two ormore training faculty:

Hilary Anderson, Development of insect ner-vous systems

Richard Carlsen, Cell biology of axonal andmuscle regeneration

Leo Chalupa, Prenatal development of mam-

malian visual systemCarol Erickson, Morphogenesis and differen-

tiation of neural crestMark McNamee, Molecular biology of ACh

receptorsBrian Mulloney, Generation and modulation

of motor patternsPamela Pappone, Biophysics of ion channelsRobert Scobey, Retinal physiologyBarry Wilson, Cholinesterases and neurotoxi-

cologyMartin Wilson, Cell biology of the retina

For more information, contact Dr. Bran Mul-loney, Director, Cellular Neurobiology TrainingProgram, Department of Zoology, University ofCalifornia, Davis, CA 95616, or phone

(916) 752-74868.UCD Is an Equal Opportunity/Affirmative Action institution.

RESEARCH

SCIENTIST

Molecular Biologist / VirologistImmunologist (Ph.D.) to developrecombinant DNA-based vaccinefor dengue virus, a mosquito-bourne agent responsible forhigh levels of morbidity through-out the tropical Third World.

Duties will involve molecularcloning, identification and char-acterization of viral sequencesencoding viral protein epitopesrecognized by human convales-cent sera, incorporation of thesesequences into vectors togenerate immunogens, andanalyzing sera elicited by theseimmunogens.

Please send your application,curriculum vitae, and the names,addresses, and phone numbersof three references to:

Dr. Tom HumphreysDirector of Research

Hawaii Biotechnology Group, Inc.99-193 Alea Heighs Drive

_- Honolulu, Hawaii 96701

An Equal Opportunity Employer

ffi64jJ UMONJ-Graduate School ofBiomedical Sciences

N E W E R S E Y

Announces a Ph.D. Graduate Program in MolecularGenetics and Microbiology at UMODJ-Robert Wood John-son Medical School

Director: Sidney PestkaAssociate Director: Victor Stollar

FACULTY RESEARCH INTERESTKenneth J. Breslauer Nucleic acid structure and drug DNA binding

studies; elucidating molecular recognitionpatterns.

Joseph P. Dougherty Retrovirus replication and retrovirus vectors.Donald T. Dubin Bacterial antibiotic resistance; HIV structure

and diagnosis.Jerome A. Langer Interferon and interferon receptors.Michael J. Leibowitz Viruses and plasmids of yeast; molecular

parasitology.John Lenard Enveloped virus proteins, fungal hormones,

multiple drug resistance.Joachim W. Messing Regulation of gene expression in plants, M13

cloning, gene synthesis.Julian J. O'Rear Cell cycle regulation, human genome struc-

ture and function.Sidney Pestka Interferon, receptors, cloning and expression

of proteins.Abbas Rashidbaigi Interferons and their molecular mode of

action.Yacov Ron Differentiation of T and B lymphocytes.R. Walter Schlesinger Mechanisms of viral neurovirulence.Aaron J. Shatkin Mechanisms of gene expression in eukaryotic

cells and viruses.Stanley Stein Synthesis and analysis of peptides and

proteins.Victor Stollar Virus-host cell interactions of arboviruses.Evelyn M. Witkin DNA repair and induced mutagenesis in

bacteria.These faculty from UMDNJ-Robert Wood Johnson Medical School andRutgers, The State University of New Jersey, including the New JerseyCenter for Advanced Biotechnology and Medicine are the nucleus ofa growing graduate program. This program will provide courses,research rotations, and thesis research opportunities in laboratorieswith sophisticated instrumentation and computer access.Merit-based fellowships are available providing an annual stipendof $10,000 plus tuition.Prospective students should write to: Director of Graduate Studies,Departnent of Molecular Genetics and Microbiolog, UMDNJ-Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway,New Jersey 8854, for more information and an application form.

Molecular

Biology BS/MS

II

The Molecular Biology Research Group of The Upjohn Company hasa position for a Research Associate to participate in research projectsinvolving thrombosis and atherosclerosis. This position requires a B.S.or M.S. degree in Biochemistry or related field, and research experi-ence in recombinant DNA techniques. Experience in cDNA synthesis,protein purification and/or mammalian cell expression techniques ishighly desirable. This position offers a challenging research environ-ment and the opportunity to participate in a multidisciplinarygroup working on the basic science aspects of atherosclerosis andthrombosis.Kalamazoo is located in Southwestern Michigan midway betweenChicago and Detroit and offers varied cultural events, cosmopolitanshopping and entertainment, lakes and woodlands minutes away,abundant year-round sports and recreation. Upjohn offers advance-ment opportunities, a highly competitive salary commensurate withexperience, comprehensive benefits and relocation assistance. Forconfidential consideration, please call from outside of Michigan tollfree 1/800/253-8600, ext. 3-6767, (inside Michigan call collect616/323-6767) to request an employment application be sent to youimmediately. Please refer to advertisement number 22415-A whencalling. We are an Equal Opportunity Employer M/F.

Our Commitment to ScientificExcellence Continues...

POSITIONS OPEN

NEARSHORE PROCESSES. The U.S. GeologicalSurvey is seeking candidates for a RESEARCH POSI-TION in nearshore processes. The successful applicantwill be part of the USGS Coastal Program andw workwith an interdisciplinary team, composed of investigatorsfrom universities, State agencies, and the USGS, whoseresearch is focused on the processes causing coastalerosion. Candidates should have a comprehensive quan-titative background in nearshore processes, for example,in physical oceanography of the nearshore, particularlythe surf zone, and the physics of nearshore sedimenttransport. Experience in designing and conducting near-shore field studies involving deployment of large arraysof instruments is desirable. Requirements are a Ph.D.and proven ability or dearly demonstrated potential forcreative, independent rsearch and publication of re-search results m refereed journals. The position will be a4-year term appointment at the GS-12 to 14 level withthe Branch of Atlantic Marine Geology in Reston,Virginia (Washington, DC metropolitan area). Appli-cants should submit resume, brief description of researchinterests, three letters of recommendation, and SF 171(Personal Qualifications Statement-available from U.S.Post Offices) to: Dr. Asbury H. Salknger, ChairmanSearch Committec, U.S. Geological Survey, 914 Na-tional Center, Reston, VA 22092. The USGS is anEqual Opportunity Employer. Applications must be re-ceived no later than 8 April 1988.

United States Departnent of Agriculture (USDA),Agricultural Research Service (ARS). NMR SPEC-TROSCOPIST position at the Northern Regional Rc-search Center, Peoria, Illinois. Successfiul candidate willoperate a new Bruker MSL 300 solid-state NMR spec-trometer equipped with a CRAMPS probe, as wel asmultinudear probes for CP/MAS and wide line NMRstudies and will participate with multidisciplinary teams(i) investigating molecular dynamics of phospholipidsand enzyme interactions in plant cell membranes, (ii)characterizing plant components such as starches, vegeta-ble oils and polyisoprenes and (iii) determining structureof lipid films and coatings and starch-synthetic polymercomposites. Applicants need a working knowledge ofphysical, organic, polymer, and analytical chemistry andan in-depth knowledge ofsolid-state NMR speroscopy.A Ph.D. in chemistry with postdoctoral work in solid-state NMR applications or equivalent is required. Posi-tion is a permanent position with beginning salary of$32,567 (GS-12). For additional information on theresearch program contact: James Cavins, USDA/ARS/NRRC, 1815 North University Steet, Peoria, IL61604. Telephone: 309-685-4011. For informationon application procedures contact: Barbara Lamm,USDA/ARS, Personnel Operations Branch, NorthCentral Section, Building 419, BARC-East, Belts-ville,MD 20705. Telephone: 301-344-1542. Applica-tions in rcsponse to this advertisement should be marked8N003 and sent to: Barbara Lamm. Applications mustbe received by 15 March 1988. U.S. citizenship required.Equal Opportunity Employer.

aD9PL

PLANT MICROPROPAGATION RESEARCHTwyford Plant Laboratories, Inc., world-leader in

development and commercialization of micropropaga-tion systems, announces three immediately-available po-sitions in its expanding research department. Those withindustry experiencc are encouraged to apply.RESEARCH SCIENTISTS: Ph.D. m plant sciences

and demonstrated experience in specific areas described.(i) System Development. New micropropagation sys-

tems for selected crops, induding inorganic and organicnutrition, growth regulators, gaseous phase, toXic by-products.

(ii) Acclimation and Establishment. Micropropaga-tion, particularly greenhouse acclimation, productionand nutrition. Expericnce or tranng in agriculturalengineering is highly desirable.RESEARCH ASSISTANT: Micropropagation/Ac-

dcination. B.S. with ecperience, or M.S. m plant sciences.Experience with micropropagation systems developmentand grnhouse production required.

Applicants should send curriculum vitae and names ofdtree references to: Dr. Irwin Y. E. Chu, President,Twyford Plant Laboratories, Inc., 15245 TelegraphRoad, Santa Paula, CA 93060.

PARASITOLOGISTThe Wadswordt Center invites applications for a para-

sitologist. Applicants must have a Ph.D. specializing inparasitology with a strong background in molecularbiology. Postdoctoral expenence in molecular aspects ofparasitic diseases is desirable. Duties indude participa-tion in and su.pervision of public health reference anddiagnostic services in parasitology and development ofanindependent research program nm the molecular aspectsof parasitic pathogenesis. The Wadsworth Center ro-vides a stimulating environment for active researc aswell as participation in academic pursuits. The Center islocated in New York's Capital District, a complex ofurban, suburban and ra communities. The area isnoted for educational excellence and has outstandingcultural and recreational opportunities. Salary is com-mensurate with training and experience. Candidatesshould submit curriculum vitae and the names of threereferences to: Mchdi Shayegani, Ph.D., WadsworthCcnter for Laboratories and Research, New YorkState Departmet of Healh, Empire State Plaa,Albany, NY 12201.

PATHOLOGYDEPARTMENT CHAIRMAN

We seek a successor to rctiring chairman. Full respon-sibility for all academic and clinical programs includingPathology Lab at Albany Medical CeCntcr Hospital andVeterans Administration Medical Center. Must evidencecontinug intercst and productivity in research as well assolid track record of support and direction of teachingand residency programs. Strong administrative and man-agement skills must be cvident cither directly or throughdelegation. Must be Board-certified. Affirmative ActionlEqual Opporunity Emploer/MIF.

Interested M.D.'s should send curriculum vitae withfiull bibliography to:

Stanley D. Glick, Ph.D., M.D.Pathology Search Committee

Albany Medical College47 New Scotland Avenue

Albany, NY 12208

Ph.D.-ANESTHESIOLOGY (SURGERY)AND PHARMACOLOGY

The Section of Anesthesiology (Departmcnt of Sur-gery) is recruiting a Ph.D. with a background in neuro-sciences (i.e., neuropharmacology, neurotoxicology,neurobiology, or neurochemistry) to coordinatc anddevelop basic rcesarch under the leadership of the Direc-tor of Clinical Investigation in Anesthesiology. A com-bined appointment in anesthesiology and pharmacologyat the assistant professor level is anticipated.

Duties will includc supervision and instruction ofresidents and fellows in basic science areas and supervi-sion of graduate students and postdoctoral fellows fromtime to time. This person would bc expcted to develoD astrong collaborative basic research program to comple-ment and expand the major research focus ofthe Section,continuous intra-spinal drug infusion and related phar-macology and toxicology, in conjunction with the neuro-science disciplines at Dartmouth. Skills in quantitativeautoradiography are essential. Experience with RIA,immunocytochemistry, reccptor binding, neural tissueand cell culture, HPLC, and pharmacokinetic modelingis desirable. This person would be expected to becomeself-supporting through extramural and/or collaborativesources within 24 to 30 months.Dartmouh Medcal School is an Equal Opportuntyl

Affmative Action Employer. Submit all inquiries andapplications (curriculum vitae and three letters of recom-mendation to: D. W. Coombs, M.D., NeroscenceSearch Committee, Dartmouth-Hitchcock MedicalCenter, Hanover, NH 03756.

POSTDOCTORAL FELLOW immediate openingin cancer chemoprevention. Would be involved in chemi-cal synthesis ofvarious analogs of a phenolic inhibitor ofcarcinogenesis, and in biological assessment of the anti-mutagenic/anticarcinogenic effects of these analogs.Experience in synthetic chemisty and in chromatograph-ic separations required. Biological techniques in mamma-lian tissue culture, enzyme analysis, pharmacokineticassays, and animal bioassays desirable. Procct funded forlong period. Beginning salary $20,000 to $25,000, plusbenefts. Rcply to: Dr. Gary Stoner, Dqxertment ofPathology, Medical College of Ohio, HEB, Rm 202,C.S. #10008, Toledo, OH 43699.

PLANT BIOTECH POSMONSA leading U.S. agricultural company has immediate

openings on its plant biotechnology team in gene trans-fer and plant pathology. Qualifications for the pathologyposition include a Ph.D. and cxperience with bacterial orviral discases. Qualifications for the gene transfer posi-tion include a Ph.D. or M.S. with experience inAgrobac-terium transformation.Send curriculum vitae and refcrences to:

Dr. C. E. GreenVice President of Research

George J. Ball, Inc.P.O. Box 335

West Chicago, IL 60185Equal Oortunity Empklyer

MSU-DOE PLANT RESEARCHLABORATORY

MICHIGAN STATE UNIVERSITYPIANT MOLECULAR BIOLOGY

The MSU-DOE Plant Rcsearch Laboratory has avail-able a tenure-track faculty position which can bc filled atthe ASSISTANT OR ASSOCIATE PROFESSORlevel. Applications arc being sought from individualswho propose to establish a research progam focused onthe investigation offundamnental problems in plant biolo-gy at the molecular and cellular level.The Plant Research Laboratory is operated under a

contract from the U.S. Dep nt of Energy andprovdes a stimulating atmosphere and excellent facilitiesfor rescarch in expermental plant biology. Generouslaboratory space and set-up support will be provided. Anongoing allocation of research funding is associated withthe position.

Applicants must have postdoctoral research experiencewith demonstrated productivity and evidence of poten-tial for independent and innovative research; seniorapplicants should have an established independent re-search program. In order to assure consideration, appli-cations should prefcrably be received by 15 February1988. Send curriculum vitae, a description of researchexperience and futu research plans, and have threeletters ofreference sent to: C. R Somerville, Chairman,Search Committee, MSU-DOE PlantR rch Labo-ratory, Michigan State University, East Lansing, MI48824.Miyan Stat UnirtyaanEqal OpportunstylAffinrative on Employer.

POSTDOCTORAL ASSISTANT (READVER-TISED), Department ofEnvironmrental Health, Univer-sity of Cininnati-Postdoctoral research position inchemical carcinogenesis available immediatc y. Positioninvolves the synthesis and identification of metabolitesand characterization ofDNA and hemoglobin adducts inbiological systems. Ph.D. in chemistry/biochemistry isrequired. Background should indude synthetic and spec-troscopic techniques and familiarity with cell culturetechniques. Send rdsume and three letters ofrecommen-dation to: Dr David Warshawsky, Deparment ofEnvironmental Health, University of CincinnatiMedical Centcr, Cincinnati, OH 45267-0056. AnEqual OpportunitylAffiswatieAction Employer.

POSTDOCTORAL FELLOWSSeveral postdoral al fellowship positions are available

as of July 1988 wit newly established search founda-tion. Areas of interest inclde basic and clinical researchin the fields of lipid/lipoprotein physiology and metabo-lism, molecular biology, animal models and cell biology.M.D.'s or Ph.D.'s with backgrounds in these or relatedfields are encouraged to submit curriculum vitae to: W.Virgil Brown, M.D., via:

Elizabeth V. CollardMedlantic MCorporation

Human Resources #260100 Irving Street, N.W.Washington, D.C. 20010Equal Opporunity Employr

POSTDOCTORAL POSITION available to studybiochemical basis for antiviral activity ofnovel nudeosideanalogs. Experience in enzyrmology, nudeic acid bio-chemistry and cell culture is desirable. Send resume andthree letters of reference to: Dr. W. Pruso1f Depart-ment of Pharmacology, Yale University School ofMedicine, New Haven, CT 06510. An Equal Opportu-ntlAffir vAcion Emtloyer.

SCIENCE, VOL. 239522

POSITIONS OPEN POSITIONS OPEN

The Center for Neural Science of NewYork University invites applications fortenure-track faculty positions in the gen-eral area of systems and integrativeneuroscience. Candidates should be ableto demonstrate excellence and originalityin experimental and/or theoreticalresearch. Appointments may be made atany level. The Center for Neural Scienceis a newly-formed interdepartmental unitof the Faculty of Arts and Science; itsmembers are drawn from the Departmentsof Biology, Chemistry, Computer Science,Mathematics, Physics and Psychology.New members of the Center will holdappointments jointly in the Center andone or more of these Departments.

Candidates should send curriculum vitae,a statement of current research interest,copies of recent relevant publicationsand the names and addresses of three ormore individuals, willing to provide lettersof reference, to: NYU Faculty of Arts andScience, Center for Neural Science, 6Washington Square North, New York,New York 10003. Attn: Professor J.Anthony Movshon.

AY IVuTt tusIE'uOptuty/%THAK'w, saloStEVioI

NYU is an EqualOporunty/Af0amco Empobt

Program Resources, Inc. (PRI) isat the forefront of biomedicalresearch, paving the way for newprograms and discoveries at theNational Cancer Institute-Frederick Cancer ResearchFacility, Frederick, MD. We haveimmediate opportunities availablein the Laboratory of Cell andMolecular Structure, a multidisci-plinary laboratory with programsin molecular genetics, virology,immunology, and cell biology, aswell as ongoing commitments toAIDS and related retrovirusresearch.STAFF SCIENTISTSTwo staff positions exist forscientists with a PhD in Molecu-lar Biology or a related field ofstudy and minimum of threeyears of postdoctoral experiencein recombinant DNA technology.Candidates should have interestsin gene structure/function andexpression, and demonstratedskills in DNA sequencing, mole-cular cloning, restriction enzymemapping, preparing and screen-ing genomic and cDNA libraries,prokaryotic and eukaryoticexpression vectors, and moderncomputational methods for DNAsequence analysis.Responsibilities will include par-ticipating in new and ongoingresearch projects, and providingexpertise and assistance inDNA/RNA characterization tovarious research teams. The abil-ity to teach, devise suitable pro-

tocols, and function as a teammember is essential.POSTDOCTORAL SCIENTISTSThese positions require a PhD inMolecular Biology, Virology, orBiochemistry, and a strongrecord of achievement. Appoint-ments are for one year, but maybe considered for renewal on ayearly basis for up to three years.Selected candidates will workwith senior staff scientists inconceiving, developing, and solv-ing a variety of research prob-lems in contemporary virology.Emphasis will be placed on AIDS,human immunodeficiency virus,and related retrovirus (lentivirus)research. We will provide trainingin recombinant DNA technologyin state-of-the-art labs that stresstechnology development. Oppor-tunities to publish and attendmeetings will be available.RESEARCH TECHNICIANSWe are looking for individualswith a BS or MS degree in theBiological Sciences and at leastone year of experience withrecombinant DNA technology,including DNA sequencing, clon-ing, restriction enzyme mapping,blotting, and propagating andpurifying plasmids and phage.Positions are also availablerequiring biochemistry tech-niques of Western blotting,radioimmunoprecipitation, affinitycolumn work and tissue culture.In addition to the exciting profes-sional challenges you'll find atPRI, we provide a competitivesalary and excellent benefits,including a tax-deferred savingsplan, a health and dental plan,educational assistance, a creditunion, and more. Relocationassistance is available at the PhDlevel.Find out what the future holds foryou at NCI-FCRF. Please sendyour resume to: ProgramResources, Inc., PersonnelDepartment, NCI-FrederickCancer Research Facility, P.O.Box B, Building 244, Frederick,MD 21701. An Equal OpportunityEmployer, M/F.

PROGRAMRESOURCES, INC.

MOLECULARBIOLOGISTS

POSITIONS OPEN

POSTDOCTORAL POSMIION available. Projectinvolves the use of three-dimensional reaggregates andhybrid cell line tissue cultures to study the trophic factorsand/or membrane proteins involved in innervation ofstriatal target cells by dopamine cells derived from thecentral nervous system. An immunological approachinvolving the generation of monoclonal antibodies tospecific proteins of hybrid cell lines derived from thecorpus striatum will be employed. Experience with tissueculture and immunohistochemistry techniques is desir-able. Send curriculum vitae, names and addresses ofthreerefcrences, and description of research experience andinterests to: Dr. A. Hcller, Department of Pharmaco-logical and Physiological Sciences, University of Chi-cago, 947 Est 58th Street, Chicago, IL 60637. TheUnivesity of Chicago is an Equal Opportunity Employer.

POSTDOCTORAL POSITION available in molec-ular neurobiology in neurodegenerative diseases, indud-ing Alzheimer's disease, in established multidisciplinarylaboratory. Qualifications include a Ph.D. or M.D., and astrong background in biochemistry and molecular biolo-gy to explore the molecular basis of these diseases.Submit curriculum vitae and three references to: Dr.Carol A. Miller, Department of Pathology, USCMedical School, 2011 Zonal Avenue, Los Angeles,CA 90033.

POSTDOCTORAL POSMIION open now to studyde novo assembly of a simple human virus. Requirescxpression of hepatitis B viral antigens in frog oocytesand mammalian cells, study of interactions betweendifferent antigens and sequential building of the viralsubstructures [Standring et al., PNAS 83, 9338 (1986)].HRI (Director, William J. Rutter) employs state-of-the-art methods to study various biological problems.Molecular or cell biology experience essential. Curricu-lum vitae and references to: Dr. David StandringHormone Research Institutc, Department of Bio-chemistry and Biophysics, University of Califionia,San Francisco, CA 94143-0534. Telephone: 415-476-8548.UCSF is an Equal OpportunitylAffiativ Action

Employer.

POSTDOCTORAL POSITION available immedi-ately for full-time participaton in a research progstudying the molecular genetics ofhuman collagen disor-ders. Project involves patient screening, genomic cloningand DNA sequencing. Significant expenence in molecu-lar biology preferred. Send curriculum vitae and namesof three references to: Dr. Jeffrey L. Doering, Depart-ment of Biology, Loyola University ofChicago, 6525North Sheridan Road, Chicago, IL 60626. An EqualOpportunity Employer.

POSTDOCTORAL POSMIION available for animmunologist/immunochemist to join our on-goingstudy on te applications of monoclonal antibodies fordetection and treatment of bladder cancer. Experiencewith monodonal antibody technology is preferred. Sendresponse to: Dr.- Chi-Wdi Lin, Director, UrologyResearch Laboratory and Department of Surgery,Harvard Medical School, Massachusetts GeneralHospital, Fruit Street, Boston, MA 02114.

POSTDOCORAL POSMIION available immedi-ately to study the use of a new type of liposome for drugdelivery. Experience or interest in pharmaceutical indus-try desirable. A doctoral degree in chemistry, biochemis-try, biophysics, pharmacology, microbiology, biology, orother related sciences are required. Annual stipend$17,00 to $19,000, or higher, depending on qualifica-tions. Please send curriculum vitae to: Dr. Sinil Kim,Univerity of California, San Diego, Cancer Center,T-012, La Jolla, CA 92093. An Equal Opportunity/Affirmativ Acaion Emtloyer.

POSIDOCTORAL POSMIION: Available imme-diately to study the regulation of whole body and tissueprotein metabolism using stable isotope technology innormal and diabetic humans. Excellent opportunity fortraining in biomedical mass spectrometry. M.D. orPh.D. in physiology, biochemistry, or related area. Applywith currculum vitae to: K. Sroe Nair, MD., Ph.D.,Endocrine-Metabolism Unit, Monroe CommunityHospit UnIversity of Rochester, 435 East Henriet-ta Road, Rochester, NY 14603-0905.

POSTDOCTORAL POSMONPhosphoinositide metabolism: postdoctoral psition.

Starting summer 1988. Recent Ph.D.'s in biohe'nmistryare invited to apply for a research appointment in ourlaboratory focussing on the regulation of phospho-inositide metabolism in human platelets. Please sendresume detailing familiarity with aboratortechniques,and names ofthree references to: Dr. S. E. Rttenouse,Department of Biochemistry, Given Building, Uni-vrity ofVermont, Burlington, VT 05405.

POSTDOCTORAL POSMON IN NEUROBI-OLOGY: Available immediately to study the role of celladhesion molecules in axon guidance and nerve regenera-tion. The applicant shoul[ be a recent Ph.D. with astrong background in membrane protein biochemistry orcell biology. Send curriculum vitae, summary of researchcxperience, and three letters of reference to: Dr. VanceLemmon, Department of Neurobiolo Anatomyand Cell Science, University of Pittsburgh, Pitts-burgh, PA 15261. The Univpesyt of Pitusbugh is anAffirma AtonEqual Opportunity EmployerDREXEL POSTDOCTO0RAL POSMIION IN

BIOMEDICAL ENGINEERING ANDSCIENCE INSTITUTE

Position commencing immediately. Perform theoreti-cal and experimental analyses of the human cardiovascu-lar system under acceleration stress. Assist in the design,development and testing of new modes ofg protection.Ph.D. or equivalent required along with background inadvanced math, biomedical instrumentation, micropro-cessor control, and/or fluid dynamics. Send resume to:Dr. DovJaron, Director, Biomedical Engineering andScience Institute, Drexel University, 32 and est-nut Streets, Philadelphia, PA 19104.

POSTDOCTORAL POSITION-RESEARCHHEMATOLOGY: The Hematology Division of theJohns Hopkins University School of Medicine has aposition available now for an individual with an M.D. orPh.D. degree and an interest in experinental hematology(erythropoietin, regulation of hematopoiesis). U.S. citi-xenship reurd Send curriculum vitae and three refer-ences to: F. L. Spivak, M.D., Hematology Division,Ihe Johns Hopkins Hospital, Baltimore,MD 21205.Equal Opponsty/Affinnaiection Employer.

TWO-YEAR POSTDOCTORAL POSMIION inplant ecology/chemistry available immediately to study

wlderod hemstryandresistance tO gallmnakhng insectsn collaboration wih evolutionary ecologists and popula-tion geneticist. Research includes correlative studies ofsecondary metabolites with plant resistance, isolation andidentification of compounds with potential resistanceproperties, and development of bioassays for antioviposi-tion agents and larval toxins. Diterpenoid and phenolchemistry, GC/MS, and HPLC experience highly desir-able. Send curriculum vitae and three letters of recom-mendation by 20 February 1988 to: Dr. Warren Abra-hamson, Department of Biology, Bucknell Universi-ty, Lewisburg, PA 17837. Affirnative Acnion Employr.

APPOINTMENT POSITION INMOLECULAR BIOLOGY

CLEVELAND CLINIC FOUNDATIONThe newly established Department of Molecular Biol-

ogy is seeking applications for postdoctoral positions inthe areas of rlation of RNA virus gene expression(Amiya K Baneree) and biochemical and biologicalstudies of protooncogenes action (Dennis W. Stacey).Experience in recombinant DNA technology and bio-chemical and tissue culture techniques desirable. Pleasesend curriculum vitae, statement of research interests andnames of three references to:

Dr. Amiya K. BanerjceDepartment of Molecular Biology

Research InstituteIhe Cleveland Clinic Foundation

9500 Euclid AvenueCleveland, OH 44106

POSTDOCTORAL POSITIONS:To study mechanism of signaling via insulin receptor

kinase. Experience in recombinant DNA or monoclonalantibody technology required. Send curriculum vitae andnames of three references to: J. Avruch, Chief, DiabetesUnit, Massachusetts General Hospital, Boston, MA02114.

POSTDOCTORAL POSITIONS IN PHARMA-COLOGY available immediately. (i) Immunophar-macology (IP)-to study immunological modeling ofreceptors and the use of antibodies as drugs. Experiencein one or more of the following: tissue cuulre ormonoclonal antibody production, immunochemistry,protein biochemistry, or neuropharmacology. (ii) Behav-ioral Pharmacology (BP)-to study effects of psychoac-tive drugs on schedule-controlled behavior. A back-ground in drug abuse research or operant conditioning isrequired. Competitive salary. Must have Ph.D. and U.S.citizenship or permanent visa. Send application indudingcurriculum vitae and names of references to: S. MichaelOwens, Ph.D. (IP), or Donald E. McMillan, Ph.D.(BP), Department of Pharmacology, University ofArkansas for Medical Sciences, Mall slot 611, 4301West Markham Strect, Little Rock, AR 72205. AnEqual Opportunity Employer.

POSTDOCTORAILRESEARCH ASSOCIATE.A position is available for an individual with a Ph.D. inpharmnacology, biochemistry or cell physiology. The suc-cessfull apphcant will be engaged in research involvingthe effects and mechanisms of action of atrial natriureticfactor in cultured vascular and renal cells, with particularemphasis on calcium, cyclic nucleotide metabolism andcell proliferation. Competitive salary and fringe benefitsare available. Appointment will be for 1 year, withpossibility of renewal. Please send curriculum vitae andthree letters of recommendation to: Dr. Aviv Hassid,Department of Pharmacology, University of Tennes-see, Memphi;s, TN 38163, or tdelphone: 901-577-4827. The University ofTennessee is an Equal OpportunitylAffimativAction Employer.

POSTDOCTORAL RESEARCH POSITION INMOLECULAR/QUANTITATIVE GENETICSA position for a postdoctoral research associate is

available in the Department of Genetics, North CarolinaState University, to work on the molecular basis ofquantitative genetic variation. The successful candidatewill undertake the molecular analysis of P element-induced variation for bristle traits in Drosophda melano-gaster. Experience in in situ hybridization, restrictionfragment analysis, cloning and sequencing is desired, andsome knowledge of quantitative genetics would be anasset. The position is available effective immediately or ata mutually agreeable date, and the salary is commensu-rate with research experience. Please send a completecurriculum vitae and three letters of reference to: Dr.Tmrdy F. C. Mackay, Department of Genetics, Box7614, North Carolina State University, Raleigh, NC27695-7614. The closing date for applications is 29February 1988, or when a suitable candidate is found.North Carolina State Unisity is an Affirmative ActionlEqual Oppornunity Employer.

U.S. DEPARTMENT OFAGRICULTURE (USDA)

AGRICULTURAL RESEARCH SERVICE(ARS)

POSTDOCTORAL RESEARCH ASSOCIATEPOSITIONS-Positions are available at the NorthernRegional Research Center, Peoria, Illinois, in four areasofresearch: (i) glycoprotein biosynthesis and secretion inmaize endosperm induding enzymology of synthesis,structural studies of oligosaccharides, and targeting ofproteins; (ii) regulation of lipid metabolism in soybeansmcluding the measurement of enzyme activities duringtemperature acclimation and isolation and characteriza-tion of theenzymes; (iii) genetic regulation of oligosac-charide biosynthesis in soybeans, including enzymology,protein structure and cloning of key metabolic enzymes,(iv) characterization of amylses, glucosidases and dex-trinases found in germinating corn induding identifica-tion of enzymes capable of invasion and hydrolysis ofintact starch granules. Knowledge and experience inenzyme assays, protein isolation or purification required.Appointments will be at GS-11 ($27,716) for 1 year andcan be extended. Please send curriculum vitae and namesof three references to: Helen Sweeny, Personnel De-partment, USDA-ARS-Northern Regional ResearchCenter, 1815 North University Street, Peoria, IL61604. Applications in response to this announcementmust be marked 8N005. Additional information may beobtained by calling; (i) J. A. Miernyk, (ii) Tom M.Cheesbrough, (iii) Tsung M. Kuo, (iv) Clarence A.Knutson at 309-685-4011.ARS is an Equal Opporuni-t Employer.

SCIENCE, VOL. 239524-

POSITIONS OPEN POSITIONS OPEN

The Department of Pharmaceutics R&D at Smith Kline and FrenchLaboratories is seeking a qualified candidate to join an innovativebiopharmaceutical development group. The primary responsibilityfor the available position is to create and validate new analyticalmethods to quantitate the potency, stability and solubility ofmacromolecular drug substances and products. Other responsi-bilities include the application of the developed methods tocompletely characterize new macromolecular drugs and to provideanalytical support for formulation scientists. The successfulcandidate is required to have a Ph.D. degree in chemistry orbiochemistry with a demonstrated ability to develop analyticalmethods. Good written and oral communication skills are alsoessential. Experience in the manipulation, analysis and chemicalmodification of enzymes including electrophoretic, chromato-graphic and spectroscopic techniques is preferred.Smith Kline and French Laboratories is located in suburbanPhiladelphia in a modem and well-equipped facility. We offer anexcellent compensation, benefits and relocation package as wellas opportunities for personal and professional growth. Pleaseforward your curriculum vitae to: Marianne Shandy, Manager,Personnel Relations-R&D, C0069, Smith Kline & FrenchLaboratories, P.O. Box 1539, King of Prussia, PA 19406-0939.We are an equal opportunity employer. M/F/H/V.

Gallfor AbstractsNORTH AMERICANCYSTIC FIBROSISCONFERENCE

Orlando, FloridaSeptember 28-October 1, 1988

Presented by the Cystic Fibrosis FoundationA Multidisciplinary Conference

for Researchers, Physcians, and AlUiedHealth Profeioals on Advances in CF

Research and Care.PLENARY SESSIONS: In Search of the Basic Defect

* Immunological Approaches to Lung Disease mPathophysiology-Bridge from the Lab to the Bedside

SYMPOSIA: Search for the CF Gene * ClinicalGenetics * Characterizing Ion Channels * Regulation

of Ion Trnsport * Biology of Pseudomonas * Infection* Transplantation * Cardiopulmonary Management

* Controversies in CF Care * Nutritional Assessment*Adult Care Considerations* Psychosocial Issues

ABSTRACT DEADLINE: APRIL 1, 1988Forfurther inforation, contact the

Cystic Fibrosis FoundationCystIC 6931 Arlington RoadRFbroSis Bethesda, MD 20814 U.S.A.FOULdCaIOl Telephone: (301) 951-4422

Simon Fraser UniversityDEPARTMENT OF BIOLOGICAL SCIENCES

Applications are invited for the following three positions which are availableimmediately:BEHAVIOURAL ECOLOGY: a tenure-track position available at the Assistant Professor levelin the general area of Behavioural Ecology. The successful candidate is expected tocontribute to the Department's Behavioural Ecology graduate programme via teaching andsupervision of graduate students, and to participate in the Department's undergraduateteaching program. Applicants should have a demonstrated competence in the area ofevolution and behaviour.INSECT PHYSIOLOGY/BIOCHEMISTRY: a tenure-track position is available at the AssistantProfessor level for an insect physiologist/biochemist. Area of research specialization open.The successful candidate will develop a graduate course in insect physiology and itsrelationship to pest management, and will contribute to the departmental undergraduateteaching program, possibly in developmental biology and/or animal physiology. He/she willdevelop a vigorous research program involving the training of graduate students and willparticipate in the Department's Master of Pest Management program.PESTICIDE BIOCHEMISTRY/TOXICOLOGY: a tenure-track position available at the Assist-anVbeginning Associate Professor level for a person with expertise in the use,biochemistry and toxicology of pesticides. The successful candidate will develop coursesdealing with the mode of action and use of chemical pesticides to service the Master ofPest Management and Environmental Toxicology programs. He/she will also contribute toother areas of the biological sciences curriculum and will develop a productive,independent research program including the training and supervision of graduatestudents. Area of research open.

Applicants should submit an up-to-date curriculum vitae, an outline of researchinterests, selected reprints of published research, and request three letters of reference besent to:

Dr. L M. Srivastava, Chairman,Dept of Biological Sciences,Simon Fraser University,Burnaby, B.C., Canada,V5A 1S6.Closing date for applications is FEBRUARY29, 1988 or when the positions are filled.

In accordance with Canadian Immigration regulations, this advertisement is directed inthe first instance to the attention of those individuals legally entitled to work permanentlyin Canada.

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LET THE SCIENCE FREE PRODUCTINFORMATION SERVICE PUT YOU INTOUCH WITH THE VENDORS WHOSEPRODUCTS YOU WILL NEED.

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SCIENCE MAGAZINENEW LAB SERVICE DEPT.1I515 BROADWAYNEW YORK, N.Y. 10036

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POSITIONS OPEN

POSTDOCTORAL RESEARCH ASSOCIATE inthe area of membrane physical biochemistry. We aresystematically investigating the effects of alcohols andanesthetics on the physical properties of individual mem-brane lipids, proteins, and simple lipid mixtures usingNMR, fluorescence, and differential scanning calorime-try. Ph.D. in chemistry or biochemistry required. Sendcurriculum vitae and names of three references to: Eliza-beth S. Rowe, Ph.D., Research Service (151), 4801Linwood Boulevard, Kansas City, MO 64128. Tele-phone: 816-861-4700 extension 541. (Affiliated withthe Biochemistry Department of the University of Kan-sas Medical School). An Equal OpportunitylAffirmativeAction Employcr.

POSTDOCTORAL RESEARCH POSITIONavailable immediately in multidisciplinary studies of ag-ing connective tissue. Individual should have back-ground in biochemical microtechniques. Experience withtissue culture desirable. Starting salary $20,000. New cellbiology/biochemistry laboratory. Send curriculum vitaeand names of three references. Lynette Feeney-Burns,Ph.D., Mason Institute of Ophthalmology, Universi-ty ofMiss olumbia, Columbia, MO 65212.AnAffirmativeAction/Equal Opportunity Employer.

POSTDOCTORAL RESEARCH POSITIONSavailable spring/summer of 1988 to study neuropeptideprecursor processing enxymes that are required for sub-stance P and enkephalin biosynthesis. Investigations willinclude enzyme characterization/regulation and determi-nation of their role in the control of peptide neurotrans-mitter formation. Experience in protein/peptide chemis-try and/or molecular biolog is preferred; Ph.D. requiredin biochemistry or related area. Send curriculum vitaeand names of three references to: Dr. Vivian Hook,Department of Biochemistry, Uniformed ServicesUniversity of the Health Sciences, 4301 Jones BridgeRoad, Bethesda, MD 20814.

RESEARCH ASSISTANTResearch assistant-investigation of the hormonal fac-

tors regulating growth of infants, children and adoles-cents. Measurement of urinary growth hormones andgrowth hormone growth factors. Analysis and interpre-tation of the data in various growth pathologies. Labora-tory techniques required inc[ude radioimmunoassays andhigh performance liquid chromatography. Require M.D.and 2-year fellowship in pediatric endocrinology. Salary:$22,000 per year. Mail resume to:

NYS Job ServiceJob Order #010439968 West Huron StreetBuffalo, NY 14202

RESEARCH ASSISTANT PROFESSOR to workin the area of biosynthesis and regulation oflipoprotein(a), a genetically determined lipoprotein covalentlylinked to a plasminogen-like glycoprotein. Previous expe-rience in cell biology required. Requires two letters ofendorsement sent to: Lipoprotein Study Unit, Univer-sity of Chicgo, 541 South Maryland, Box 231,Chicago, IL 60637. Contact: Ms. Kass 312-702-1378. The University of Chicago is an Equal OpportunityEmployer.RESEARCH ASSISTANT PROFESSOR to study

redox proteins in glyoxysomal and ER membranes,orientation ofthe component cytochromes and flavopro-teins, identify electron acceptors; train graduate andundergraduate students. Ph.D. in biochemistry, biology,or botany required. Experience in the isolation oforgan-elles and membrane proteins preferred. Contact: Dr. R.Donaldson, Biology Department, Gcorge Washing-ton University, Washington, DC 20052. An EqualOpportunity/Affirmatve Action Employer.

RESEARCH ASSOCIATE in excellent researchenvironment. Ph.D. and experience, as evidenced inpblications, in either biochemistry, enzymology, cellbiology, nutrition or molecular biology. Studies focus onthe role of environmental or nutritive stress on eye lensfunction. Potential for faculty status. Send resume andthree letters of reference to: Dr. Allen Taylor, Director,Laboratory for Nutrition and Cataract Rcsearch,USDA Human Nutrition Research Center on Agingat Tufts University, 711 Washington Street, BostonMA 02111. An Affirmative ActionlEqual OpportunityEmi,krvr.

RESEARCH ASSOCIATE. Position available tostudy the effects and mechanisms of action of clinicallyuseful and/or neurotoxic psychotropic agents includingpsychomotor stimulants on survival and function ofspecific transmitter-containing neurons (dopamine, sero-tonin, GABA) in three-dimensional reaggregate tissuecultures. Experience with tissue culture and analysis ofneurotransmitter function by HPLC techniques desir-able. Send curriculum vitae, names and addresses ofthreereferences, and description of research experience andinterests to: Dr. A. Helier, Department of Pharmaco-logical and Physiological Sciences, University of Chi-cago, 947 East 58th Street, Chicago, IL 60637. TheUnivrity ofChicago is an Equal Opportunity Employer.

RESEARCH ASSOCIATES. (i) A protein bio-chemist/enzymologist to study phosphorylation sites incardiac troponn subunits by protein kinase C and effectson Ca2+ sensitivity and activity of actomyosin ATPase.(ii) A cell biologist/pharmacologist to study proteinkinase C system in growth and differentiation ofculturedcells and in development and aging of animal tissues.Send application to: Dr. J. F. Kuo, Departments ofPharmacology and Biochemistry, Emory UniversitySchool of Medicine, Atlanta, GA 30322. Emory is anEqual Opportunity Employer.

RESEARCH ENDOCRINOLOGIST. An academ-ic position to investigate the molecular and cellularbiology of the calcium-regulating hormones and theirreceptors. For Ph.D.'s in the biological sciences withrelevant post-graduate training. Experience required inrecombinant DNA, peptide hormone, and receptor tech-nology. Salary established by UCSD research series.Send curriculum vitae with references to: Dr. L. J.Deftos, University of California (VIl1C), SanDiego, CA 92093. AffimativcAcaion/Equal OpportunityEmployer.

BIOGROWTH, INC.RESEARCH SCIENTISTS

BioGrowth, a biotechnology company, has immediateopenings for the following scientists:PROTEIN CHEMIST, Ph.D., with experience in

protein purification and characterization, preferably fromrecombinant organisms. Particular expertise in immuno-chemistry, affinty and HPLC chromatography, Westernblotting, and protein function analysis is required. Hy-bridoma expertise iS desired.MOLECULAR BIOLOGIST, Ph.D., with genomic

and cDNA cloning, RNA isolation and analysis, andxprcssioin of gencs in bacteria or mammalian cells.-BIOCBEMIST, B.S./M.S., with additional lab expe-

rience including gel electrophoresis, chromatography,and immunoassay development.MOLECULAR BIOLOGIST, B.SJM.S., with ad-

ditional lab experience induding cDNA library construc-tion, mRNA preparation/translation, DNA/RNA, se-quencing, and expression vector construction.

BioGrowth, located in new facilities in the San Fran-cisco Bay area, offers competitive salaries, benefits, andthe opportunity to make a major contribution at a newlydeveloping company. Please send your resume, salaryhistory, and list of three references to:

BioGrowth, Inc.3065 Atlas Road, Suite 117, Department SC4

Richmond, CA 94806

SENIOR REPRODUCTIVEPHYSIOLOGIST/BIOLOGIST

The Department of Zoology of the University ofTexas at Austin invites applications or nominations for asenior tenure-track position in vertebrate reproductivebiology. This position will be open in September 1989.We are particularly interested in candidates who special-ize in neurology or neuroendocrinology but whose con-cerns are multidisciplinary. The successful candidate willbe expected to have demonstrated a commitment toquality graduate teaching and a vigorous, independentresearch program. Please submit curriculum vitae (in-cluding biographic data), short statement of researchobjectives, names of at least five referees, and selectedreprints to: The Chairman, Department of Zoology,University of Texas, Austin, TX 78712-1064.

The Univerity ofTexas a!Austin is an Equal Opportuni-ty/Affirmative Action Employer.

SCIENTISTSExcellent career opportunities immediately available

with client companies seeking entry through senior-levelbiochemists, organic and analytical chemists. Specificacademic and/or industrial experience in immunology,enzymology, hematology, pofymers or clinical trials astrong plus. Confidentiality assured. Qualified, seriouscandidates only.

Mr. Jeff DeanMarcus and Associates

272 North Bedford RoadMt. Kisco, NY 10549

SOFTWARE ENGINEERAn immediate opening is available for a software

engineer in supercomputing research and development.This is a university position. The primary responsibilityof the position is the design and implementation of aprogrammmg environment for parallel scientific comput-mg. Duties include development of a debugger andperformance analyzer for parallel applications written in avaricty ofprogramming languages. Theprogrammer willalso develop graphics and communication tools to pro-vide user-friendly interfaces on bitmapped workstationproducts attached to a network supercomputing facility.The incumbent will also be involved wig the develop-ment of artificial intelligence tools that aid the scientificprogrammer with application development.Minimum qualifications indude: master of science in

computer science. The following required experiencemay have been obtained during graduate study or workexperience (if any): At least 6 months use ofC program-nmng language and Berkeley UNIX; design and imple-mentation of at least one compiler using LEX and YACC(UNIX compiler writing tools); use of Fortran, Pascaland Modula-2 programming languages; developmentand maintenance of artificial intelligence applicationsusing LISP and PROLOG; development of numericalapplications in a parallel processing environment. Musthave had at least one graduate course in each of thefollowing areas: programming languages, operating sys-tems, compiler design, artificial intelligence, and parallelprocessing.

Salary will be between $32,000 and $40,000, depend-ing upon experience and qualifications.Send resumes, including names of at least three refer-

ences to:Mrs. Wanda ByrdIllinois Job Service

402 North RandolphChampain, IL 61820Rcference: 7780-H

This is an employer-paid ad. Affirmative ActionlEqualOpportunity Employcr.

STAFF FELLOWSNATIONAL INSTITUTE ON

DRUG ABUSE ADDICTION RESEARCHCENTER (ARC)

Applications are invited for possible appointments asstaff'fellows within the Preclinical Pharmacology Branchof the NIDA Addiction Research Center. This Branchconducts studies related to the behavioral pharmacologyand genetics of drugs of abuse using experimental ani-mals. Candidates must have a Ph.D. degree, with train-ing in either behavioral, biochemical or molecular genet-ics, and an interest in problems related to neuroscienceand animal models of drug abuse. The successful candi-date will be expected to initiate and conduct interdisci-plinary studies directed towards elucidating neural sub-strates of drug actions using behavioral, biochemical andmolecular methods. Initial appointments are for 2 yearswith extensions possible. Current starting salary forprsons without postdoctoral experience is $27,172

.S., with increments for relevant postdoctoral experi-ence, plus generous benefits. The Addiction ResearchCenter is located in Baltimore at the Francis Scott KeyMedical Center, a Johns Hopkins facility in close proxim-ity to Washington, D.C. Send curriculum vitae, applica-tion for federal employment (SF-171), bibliography,reprints, three letters of reference and a certified copy ofthe doctoral degree if available to: Dr. Steven R.Goldberg, Chief, Preclinical Pharmacology Branch,NIDA Addiction Research Center, Box 5180, Balti-morm, MD 21224. The ARC is an Equal OpportunitylAffinmative Action Employer MIFIHIV.

SCIENCE, VOL. 239It526

POSITIONS OPEN POSITIONS OPEN

Abbott

Fermentation

Research Run

ASteadyCourse

Advanced research projects that are wellconceived, well funded and well managed arepar for the course at Abbott Laboratories. We'rea $4.5 billion world leader with an outstandingreputation for management and technicalstrength. Those strengths show through in ourChemical and Agricultural Products Divisionand the career opportunities we offer.

Molecular Biologists/Fermentation R&DWe seek a PhD in Molecular Biology or a relatedfield to study antibiotic biosynthesis genes inStreptomyces. Experience with gene-cloningsystems in gram positive organisms and at least2 years post-doctoral experience preferred.We also seek candidates with an MS in MolecularBiology or a BS with at least 3 years industrialexperience in molecular biology. Familiarity withrecombinant DNA techniques such as DNAisolation, restriction analysis, southernhybridization and DNA sequencing are required.Reply to Job #1Microbial Geneticist/Fermentation R&DWe seek an MS or PhD with 3-5 years of industrialexperience involving fermentation strainimprovement. Must have strong interpersonaland written communications skills. Backgroundwith antibiotic-producing microorganismspreferred. Reply to Job #2

Protein Chemist/Agricultural Microbiology R&DWe seek a PhD in Microbiology/MolecularBiology with postdoctoral experience in proteinchemistry to conduct research in microbialbiotoxins applicable to agriculture. Establishprogram for mode of action studies on microbialtoxins effective against insect larvae targets.Knowledge of immunochemistry and insectphysiology preferred. Reply to Job #3Molecular Biologist/Agricultural Microbiology R&DWe seek a PhD in Molecular Biology with aminimum of 2 years postdoctoral experiencerequired. Conduct basic research in microbialpesticides and develop new products based onrecombinant strains. Good communicationskills are essential and industrial experience inmicrobial insecticides is preferred. Reply toJob #4.Abbott Laboratories is headquartered in anattractive suburban area north of Chicago. Weprovide an excellent salary and benefits programfeaturing profit sharing and employee stockpurchase plans. For more information, send aresume (indicating which position desired) instrictest confidence to: Keith Allen/CorporatePlacement Dept. S-1/29. Abbott is anAffirmative Action Employer.

_ABBOTTHABBLTT PARK IL 60064"HEALTH CARE WORLDWIDE"

LOTECHNOLOGISTJoin Nalco Chemical Company, a Fortune500 world leader in specialty chemicals, lo-cated in a western suburb of Chicago. Weseek a dedicated professional whose skill,expertise, and enthusiasm can help us main-tain our leadership in the industry.A critical position exists for a biotechnologistin our Corporate Research Department. Youwill be responsible for developing new prod-ucts and processes for many industrial spe-cialty applications.A PhD is required and post-doctoral experi-ence is desirable. The ideal candidate wouldhave an expert knowledge of molecularbiology or biochemistry and experience inenzymology or polysaccharides.Nalco offers a salary commensurate with expe-rience and a comprehensive company paidbenefits program highlighted by our excellentprofit sharing plan. For confidential con-sideration, send resume and salary history to:

NALCO

Karen NordquistEmployment Manager

Nalco Chemical CompanyOne Nalco Center

Naperville, Illinois 60566

An Equal Opportunity Employer

OAK RIDGE NATIONAL LABORATORY

The Oak Ridge National Laboratory invites nominations andapplications for the position of Director of the Laboratory.With a staff of over 4300, ORNL is the largest multiprogramenergy laboratory in the U.S. Department of Energy R&Dsystem. The Laboratory's primary missions are (1) to con-duct applied research and engineering development in sup-port of DOE's programs in fusion, fission, conservation, fos-sil, and other energy technologies and (2) to perform basicscientific research in selected areas of the physical and lifesciences. The Search Committee is seeking candidates whohave demonstrated management and leadership abilities anda distinguished record of achievement in scientific orengineering research. All communications should be sent toDr. M. W. Roswthal, Oak Rdge Nafotal Laboratory,Building 4500N, Post Offlce Box X, Oak Ridge, TN37831-6241. All applications must be received no later thanMarch 15, 19U.

operated by

for theU.S. Department of EnergyAn Equal Opportunity Employer

US. Citizenship Required (Security clearance will be required)

POSITIONS OPEN

STAFF SCIENTISTMedtronic Inc., the international leader in implantable

pacemakers, is seeking an individual with a B.S. inbioengineering or physiology and several years of experi-ence in cardiovascular research. This person will conductstudies and work with clinical consultants in evaluatingthe feasibility of novel pacing and other cardiovasculardiagnostic and therapeutic concepts. Experience in acuteand conic animal studies and use of appropriate instru-ments is essential. A Ph.D. in this ield is preferred.Submit resume/curriculum vitae to: Vemn Brewers,Medtronic Inc., 7000 Central Avenue NE, Minne-apolis, MN 55432. Equal Opportunity Employer.

SHANNON POINTMARINE CENTER (SPMC)

WESTERN WASHINGTON UNIVERSITY1988 SUMMER RESEARCH AWARDS

SPMC announces 1988 Summer Research Awards.Applications are solicited from investigators in the ma-rine sciences interested in conducting research at SPMCduring the summer of 1988. Investigators in the earlyphasc of their careers who have demonstrated the poten-tial for research productivity since receiving the doctorateare particularly encouraged to apply. The award includeslaboratory space and a $1500 stipend. We anticipateoffering four to six awards in 1988. SPMC is located inAnacortes, Washington in the northern Puget Soundbasin. Applications should include a rosum6, a descrip-tion of the specific research topic prop for 1988, anda statement of space and other fac: ties required. An-nouncement of awards will be made by mid-February,1988. Applications and inquiries should be addressed to:Dr. Stephien D. Sulin, Professor and Director, Shan-non Point Marine Center, 1900 Shannon PointRoad, Anacortes, WA 98221.

TECHNICIANTECHNICAL SPECIALIST

Researchers at SUNY Stony Brook are seeking aresearch technician (technical specialist) for AIDS viruslaboratory studying molecular virology and conductingantiviral trials. Responsibilities will include analysis ofviral DNA and RNA and cultivation of the AIDS virus.Bachelor's degree required, graduate work in biologicalsciences preferred. At least 2 years of work in molecularvirology and/or expertise in tissue culture, recombinantDNA technology, in situ hybridization, or immunohis-tochemical staining preferred. Full-time position. Call:Dr. Barbara Weiscr at 516-444-1660. SUNYT StonyBrook it an AffirmativeActionlEqual Opportunity Educatorand Employer. AK#324-A.

TENURE-TRACK JUNIORFACULTY POSMON

IN THEORETICAL PHYSICSTHE JOHNS HOPKINS UNIVERSITY

The Department of Physics and Astronomy at TheJohns Hopkins University invites applications for atenure-track faculty position at the assistant professorlevel in high energyparticle theory to begin in July 1988.Requirements indcude a Ph.D., demonstrated researchaccomplishments and good teaching ability. Applicantsshould send their curriculum vitae, the names of at leastthree references, and a brief description of their researchinterests to: Professor J. C. Walker, Chairman, De-partment ofPhysics and Astronomy, Thc Johns Hop-kins Univrsity, Charles and 34th Streets, Baltimore,MD 21218. The deadline for applications is 15 March1988. TheJohns Hopkins University is an Equal Opportuni-ty/Affirmative Action Employer.

VERTEBRATE BIOLOGIST-VISITING AS-SISTANT PROFESSOR OF BIOLOGY. St. Law-rencc University. One-year replacement; Ph.D. required.Duties conmence 24 August 1988, and include teachingcomparative anatomy and ornithology with labs, andcourses in speciality at population or organismic level.Non-sectarian liberal arts college of2000; department ofnine. Application induding curriculum vitae and threelettcrs ofrecommendation by 1 March 1988 to:

Ms. Carol BuddBiology Department

St. Lawrence UniversityCanton, NY 13617

St. Lawrence Univerity is an Affirmative ActionlEqualOpportunity Employer. Women and minorities are encour---ed to aply.

TOXICOLOGIST-PUBLIC INTERESTPosition with a national consumer advocacy organiza-

tion. Evaluate research on food additives, pesticides, andbacteria; help prepare regulatory petitions; advise con-sumers and journalists. Advanced degree, writing skills,and interest in consumer advocacy required. Salary:$30,000 to $40,000. R6sume, popular writing sample,and salary history to: Center for Science in the PublicInterest-DB, 1501 16th Street, NW, Washington,DC 20036.

VETERINARY GROSS ANATOMIST. The De-partment of Veterinary and Comparative Anatomy,Pharmacology and Physiology, College of VeterinaryMedicine, Washington State University solicits applica-tions for a tenure-track position at assistant/associateprofessor level. Duties include teaching veterinary grossanatomy to D.V.M. students and develop a viable re-search program in the area of her/his interest. Areas ofresearch in the departmcnt indude: biomechanics, bonemetabolism, neurobiology, teratology, toxicology andcellular, cardiovascular and exercisc physiology. Qualifi-cations: D.V.M./Ph.D. or Ph.D. in anatomical sciences.Candidates with demonstrated teaching and researchexperience are preferred. Rank and salary will be com-mensurate with qualifications. Written applications mustinclude curriculum vitae and the namnes, addresses, andtelephone numbers of three references. Aplications andinquiries should be addressed to: Dr. V. K. Redd,Department ofVCAPP, College ofVetc Med-cinc, Washington Statc University, Pullman, WA99164-6520. Applications deadline-15 March 1988or until the position is filled. Washington State Universityis an Equal OpportunitylAffirmative Action Educator andEmloyer. Protected GroupMcmbers are encouraged to applya dentify their status.

VISITING ASSISTANT PROFESSORS INPHAARMACOLOGY/PHYSIOLOGY. The De art-ment of Pharmacodynamics, College of Pharmacy, Uni-versity of Florida is searching for one to two visitingassistant professors to fill nontenure-track positions for*1to 2 years. Applicants must hold a Ph.D. degree inpharmacology, physiology or related fields. The candi-date will be required to participate in team teaching ofpharmacology, physiology an</or pathophysiology topharmacy students. Time may be available to conductcollaborative and independent rescarch. Current researchareas ofthe faculty in the department are aging, neuroen-docrinology, cardiovascular pharmacology, toxicologyand temperature regulation. Positions will be availabk yJuly 1988. Applicants should send curriculum vitae, adescnrption of research interests and career goals, andhave three letters of reference sent by 1 April 1988 to:Dr. Ralph Dawson, Chairman of Search Committee,Department of Pharaacodynamics, Box J487,JHMHC, University of Florida, Gainesville, FL32610. The Universt ofFlrida is an Equal OpportunitylAffirmativeActon Educator and Eloyer.The Illinois State Water Survey, located at the Univer-

sity of Illinois in Urbana-Champaign, operator of theNSF/ISWS CHILL Radar National Facility, announcesa VISITING SCIENTIST position. A medium orlonger term ofappointment is offered for research relatedto tie future development of high-performance micro-wave radars and their use in atmospheric research. Theobjective is to provide a scientist the opportunity forfrequent access to the Facility for purposes of specializedand exploratory research and for frequent exchange ofideas with the Facility staff. The appointment will bc for3 months, but may bc Ionger tor an individual onsabbatical or other paid leave from his/her home institu-tion. Renumeration will be commensuratc with theexperience of the scientist and may include some appro-pnatecxtra cxpenses. The Facility includes state-of-the-art processing technology and computer capabilities formany analysis procedures. In addition, the scientist willhave access to the CRAY XMP in the NSF-fundedNational Center for Supercomputing Applications at UIas well as other UI and ISWS computer Facilities.Experienced and postdoctoral scientists with particularinterest in the use of microwave radars in atmosphericresearch are encouraged to apply for this appointrnent bysending a r6sume and the names of three references to:Dr. Peter J. Lamb, Head, Climate and MeteorologySection, Illinois State Water Survey, 2204 GriffithDrive, Chamrapign, IL 61820.

The University ofIlinois is an Affirmative Action EqualOpportunity Emplycr.

PHYSICIAN/SCIENTIST AWARDApplications are invited for the Edward Herbert

Physican Sacntist Award sponsored by the VollumInstitute for Advanced Biomedical Research of TheOregon Hcalth Sciences University. The award providesthe opportunity and salary support for a newly trainedclinic professional with a commitment to research todevelop into an independent biomedical investigator.Training during the tenure of this award (up to 2 years)will be with a faculty sponsor from the Vollum Institute.The Institute is a major division of the university com-mitted to the application of molecular biology to basicresearch in the neurosciences. Candidates are restricted tothose holding health professional degrees in the dinicalscicnces and must provide evidence ofserious intent for aresearch and academic career. Physicians holding a Ph.D.degree are ineligible. Inquiries should be addressed to:

Dr. Michael Forte, ScientistVollum Institute for Advanced Biomedical Research

The Oregon Health Sciences University3181 S.W. Sam Jackson Park Road

Pordnd, OR 97201The Oregon Health Sciences Univcrsity is an Affirmative

Action Employcr.

SUMMER RESEARCH AWARDS IN ECOLO-GY: The Pymatuning Laboratory ofEcology, Universityof Pittsburgh has available research awards for the sum-mer of 1988. Proposals are welcome at all academic levelsfor research in any area of ecology. Support will usuallynot exceed $3500, and may include travel, equipment,supplies, assistants, and room and board at the Labora-tory. The research must be carried out at the Laboratory.Inquiries or proposals should be sent by 15 April 1988to: Pyiatuning Laboratory ofEcology, Route 1, Box7, Linesville, PA 16424.

GRANTS

THE ROGER TORY PETERSON INSTITUTEOF NATURAL HISTORY will award GRANTSfrom $500 to $5,000 for research in the areas ofgeoloy,biological sciences, and natural history. Deasinc torapplications is 31 March 1988. For information contact:Thc Roger Tory Peterson Institute, 110 MarvinParkway, Jamesown, NY 14701. Telephone: 716-665-2473.

WORKSHOP

MOLECULAR METHODS WORKSHOPFOR BIOMEDICAL RESEARCHERS

The Pittsburgh Supercomputing Center (PSC) is con-ducting a workshop on "Methods ofMolecular Mechan-ics and Dynamics of Biopolymers," 13 to 15 July 1988,funded by a grant from the Division of Research Re-sources' Biomedical Research Technology (BRT) Pro-gram of the National Institutes of Health (NIH).The workshop will familiarize biomedical researchers

with computational methods and practicc for the applica-tion of supercomputing resources to problems of con-cern in molecular mechanics. Practical experience will begained in the application to: (i) the problem of confor-mational mapping and analysis of polypeptide structures,(ii) the structural refinement of polypeptides, protcins,and nudeic acids using constraints from measured NMRdata, and (iii) computation of interaction encrgies andfree eneries for protein-drug interactions. The usc ofstate-of-the-art macromolecular computational packages,such as CHARMM and EXPLORE will be idustrated.Workshop leaders: Charles L. Brooks m, CarnegieMellon University, and Axel T. Brunger, Yale Univer-sity School of Medicine.

Travel, meal, and hotel accommodations arc coveredfor academic participants under the grant. A limitednumber of openings for industry-based biomcdical re-searchers may be available for a fee of $1,000. Thedeadlinc for the submission of applications is 15 March1988. Enrollment is limited to 20 participants.For application forms and additional information, call

or write: Biomedical Coordinator, Pittsburgh Super-computing Center, 4400 Fifth Avenue, Pittsburgh,PA 15213. Telephone: 412-268-5206.

SCIENCE, VOL. 239528

POSITIONS OPEN AWARDS

Positions OpenImClone Systems Incorporated, aninnovative, rapidly growing biotech-nology company located in NewYork City, is seeking highly motivatedindividuals for vaccine development,generation of monoclonal antibodiesand immunoassay development.

ImmunologistsPositions are available at the doctoraland research associate levels for in-dividuals with demonstrated skills inthe generation of B and T cellhybridomas. Relevant industrial ex-perience would be an advantage.Several positions are available at theB.S. level for persons with purifica-tion, PAGE, and immunodiagnosticassay formatting experience.ImClone offers excellent salary andbenefits, and a challenging, multi-disciplinary environment for scientistswho can assume both individual andteam responsibilities.Send CV to: John Landes, Im-Clone Systems Incorporated, 180Varick St., New York, New York10014.

jmo.

ImCIone Systems Incorporated

CSIROFISHERY SCIENTIST/POPULATION DYNAMICIST

(RESEARCH FELLOW)A$28,629 pa TO A$41,861 pa

DIVISION OF FISHERIES RESEARCHMARINE LABORATORIES, HOBART, TASMANIA AUSTRALIA

THE DMSION: The CSIRO Divisions of Fisheries Research and Oceanography collectively form the CSIRO Marine Laboratories. TheDivision of Fisheries Research undertakes studies into biology, ecology and population dynamics of marine populations (both plantand animal) and supplies information for the development of management strategies for fisheries within the A.F.Z. The Divisioncurrently employs about 140 staff of whom 80 are professional research stall. Laboratories are located in Hobart, Perth andBrisbane. The Division has a well equipped charter vessel (53m) available for research.

THE PROGRAM: Within the Fish Population Dynamics Section a program is established to conduct research into the trawl fishery ofthe continental shelf and shelf slope in Southeast Australian waters. Most of the catch is obtained by otter trawling and Danishseining, with 10 species comprising the bulk of the catch. This fishery is regarded as a national resource of Australia and is managedvia a management committee.

THE JOB: The appointee will undertake research into the population dynamics of exploited fish stocks in mixed stock fisheries, anddevelop and evaluate management strategies for these fisheries. This will require both integration of information currently availablethmrough advisory and management agencies and the development of biological research projects and collection of fishery data. Theappointee will provide ongoing advice to the research and management agencies of the S.E. trawl fishery.

THE PERSON: Applicants should hold a PhD degree on equivalent qualifications in quantitative Zoology or Fisheries Biology withexperience in methods of assessment of exploited populabtions. Demonstrated mathematical ability, particularly in the developmentand application of mathematical methods and models in a biological context is essential. They should have familiarity with computerprogramming and its application to scientiic problems. Post-graduate experience in population dynamics and stock assessmentwould be an advantage.

CONDITIONS: Appointment will be for a term of 3 years with Australian Govemment Superannuation benefits available.

MORE INFORMATION: Prospective applicants are invited to telephone Dr. K. Sainsbury on (002) 206222 for further information. Dr.Sainsbury can also provide a copy of the detailed job description and selection crteria.APPUCATlONS: Applications should be submitted by 26 February 1988 and quote reference number A2405. They should be framedagainst the selection crtera and should state relevant personal particulars including details of qualifications and experence.Applicants should nominate at least two professional referees, and address their applications to:

The ChiefCSIRO DOisiom of Fihdes RmarchMarin LaborlesGPO Bo 1538HOBART 7001AUSTRAUA

CSIRO IS AN EQUAL OPPORTUNITY EMPLOYER

FACULTY POSITIONAVAILABLEBIOLOGY

Tenure track faculty pos. inmolecular cell/devel. biol. ingrowing department at a majoruniversity in suburban NewYork City. Rank and salaryopen; postdoctoral experienceand evidence of research pro-ductivity are required.Teaching of both undergradu-ates and graduate students isexpected, but the successfulcandidate will have a primaryresponsibility to train Ph.D.students in a vigorous, extern-ally-funded research program.Startup funds are competitiveand newly-renovated labora-tory space is available.Candidates should submit ac.v. with list of publications, abrief statement of research in-terests, and the names of atleast three references by Mar.1, 1988 to Dr. Richard A. Lock-shin, Chair, Dept. of BiologicalSciences, St. John's Univer-sity, Jamaica, NY 11439.An Equal Opportunity Employer-MWF

YRTIsIS

LIFE SCIENCESArthur D. Little, Inc., a leading multinational research and technical con-sulting firm, has two management openings in its Cambridge,Massachusetts, Life Sciences facility.

Manager of ToxicologyPrimary management responsibilities for our in vivo toxicologyunit. Must have experience and track record in marketing andmanaging a wide range of toxicology studies. DABT and/orDATS and study director experience required. Line managerialexperience is highly desirable.

Manager of Regulatory Affairs PracticeMajor responsibilities for building our current Quality Assur-ance and Regulatory Affairs practice. Current activities involveinterfacing with laboratory-based health effects scientists andhealth care consultants in regulatory strategy and technicalregulatory submissions. Consulting activities include commer-cial as well as state and Federal government clients. Strongtrack record in regulatory affairs consulting, including prepa-ration of submission to FDA, EPA, DOT and OECD required.

Located in Kendall Square, on Memorial Drive, we offer state-of-the-artfacilities and equipment and attractive surroundings. Challenging careeropportunities with direct client contact and participation in high level plan-ning. We provide relocation assistance and an attractive compensation/benefits package.Please send resume to Jeanne Crowley, Personnel Manager, Arthur D. Little,Inc., Acorn Park, Cambridge, MA 02140. An equal opportunity employer, M/F

AL Arthur D. Little, Inc.

ASSISTANTSHIPS

GRADUATE STUDIES IN MOLECULARAND CELLULAR PHYSIOLOGY

The Department of Physiology in the College ofMedicine of the Pennsylvania State University has assis-tantships available for graduate studies in molecular andccllular physiology. The faculty of the Departmcnt ofPhysiology is known for their research in various aspectsof molecular and cellular physiology, particularly in cellstructure and function, hormone action, regulation ofgene expression, cell growth and differentiation, meta-bolic regulation, and neurotransmitters and receptors.Interested candidates are invited to apply to: Dr. Leon-ard S. Jefferson, Chairpon, Department ofPhysiol-ogy, Pennsylv State University, Milton S. Her-shl Medical Center, P.O. Box 50, Hershey, PA17033. U.S. ctizensl or perment reidnc required.An Equal OpprunityfAffinnane Acason Employer.

TRAINING PROGRAM

GRADUATE TRAINING PROGRAMSPHARMACOLOGY AND

MOLECULAR SCIENCES ANDANTICANCER DRUG DEVELOPMENTTHE JOHNS HOPKINS UNIVERSITY

SCHOOL OF MEDICINE

Opportunities for studies leading to the Ph.D. degreeare offered in the following gener areas of research: (i)Protein and carbohydrate structure/function, (ii) molecu-lar biology and gene regulation, (iii) molecular parasitol-ogy and virology, (iv) biomedical mass spectroscopy, (v)neuropharmacology, and (vi) design, synthesis, and test-in co ne drugs.7he programs foster innovative, interdisciplinary re-

search and provide competitive stipends for qualifiedindividuals. Candidates with strong potential and inter-est in Ph.D. studies in the areas listed above shouldcontact: Dr. Mette Strand, Director of GraduateTraining, Department ofPharmology and Molecu-ar Sciences, The Johns Hopkins School of Medicine,725 North Wolfe Stret, Baltimore, MD 21205.Telephone: 301-955-7117.An AffinativeActionlEqual Opportunity Employer.

FELLOWSHIPS

INTERNATIONAL CANCER RESEARCHFELLOWSHIP

The Hayashibara Mutual Aid Fund, a non- rofit-making organization within the Hayashibara Groupannounces a fellowship program. Two awards will bemade annually. Fellowship will be taken up at the newlyopened Fujisaki Cell Center which is devoted to basicand applied research related to problems in humancancer. The fellowship is normally made for 1 year and isrenewable for up to 5 years. The fellowship will beexpected to commence within 6 months ofthe announce-mcnt of the awards. The awards are for high qualityresearch work in one of the three categories describedbelow.

1) Fundamental Leukemia-Lymphoma Research,2) Cyokine-Lymphokine Research,3) Hematopoictic Cell Cultures.Qualified person who has a Ph.D., an M.D. or equiva-

lent qualifications will be awarded on merit to suitablyqualified research proposal and experiences. Additionalinformation and application forms will be obtained fromJun Minowada, M.D., Director, Fujisaki Cell Centcr,675-1, Fujisaki, Okayama 702, Japan.

NEUROBIOLOGY-POSTDOCTORALFELLOWSHIP

One- to 2-year position immediately available to studyfunctional and structural changes following nerve regen-eration and muscle reinnervation in larynx, pharynx,facial muscles and other cranial nerve systems. Comple-tion of Ph.D. required. Stipcnd level determined bycxperience. Send curriculum vitae and names and ad-dresses of three references to: Roger L. CrumleY, MD.,Chicf, Otolaryngology-Head and Neck Surgery,UCI Medical Center, 101 City Drive, Orange, CA92668. The Univerity of California is an ArmnativeAcaion/Equal Opportunity Enployer.

BOTANY-POSTDOCIORAL FELLOWSHIPAT YALE UNIVERSITY

Applications are invited for the Forest B. H. andElizabeth D. W. Brown Postdoctoral Fellowship inBotany, providing for 1year of research in thefilds ofplant molecular biology, plant development, plant physi-ology, or the evolutionary biology of vascular plants.This appointment will commence m the academic year1988 to 1989 or earlier by mutual agreement. Scndinquiries and rdsumi (curnculum vitac, reprints, andnames of three potential references) to: The Chairman,Department of Biolog, Yale Univity, P.O. Box6666, New Haven, CT06511. Application deadline: 7March 1988. Ya u s an Equa OpportunitylAffimatieAction Empkryer.

PREDOCTORAL FELLOWSHIP. R. B. Wein-traub Fellowship; training in biology in one of thesearcas: plant cell and molecular biology, peroxisomes,evolution of protists and vascular plants, molecular cvo-lution, deveopment, rcnal physiology, comparativencuroanatomy and endocrinology, ecology. Teachingfellowships also available. Contact: Dr. R Packer, Biof.ogy Dqe ment, George Washington University,Wiahingto DC 20052.

POSTDOCTORAL FELLOWSHIP available tostudy human colon carcinoma cell differcntiation both inresected tumors and in cell linc models, for 2 years,starting at $25,000 per year plus fringe benefits beginning july 1988. Candidates with a Ph.D. in cell biologyor biochemistry prcferred. Send curriculum vitae andtwo letters of reference to: Eileen Friedman, Ph.D.,Memorial Sloan-Kettering Cancer Center, Labora-tory of Gatrointestinal Cancer Research-Box 5614,1275 York Avenue, New York, NY 10021.

FELLOWSHIPS IN BIOLOGY AND ENDO-CRINOLOGY, University of California, San Diego(UCSD), for Ph.D.'s and M.D.'s for a 2- to 3-yearresearch program forJuly 1988 and January 1989 in thebiolgy of calcium metabolism. Applicants must becligibk for NIH tainirig !mts. Spific areas indude:molecular and cellular biology of calcium-regulatinghormones and their reccptors, bone matrix proteins andmincrals. Send curriculum vitae rcefrences to: Dr. L. J.Deftos, UCSD (Vl1C), San Diego, CA 92093.Affirmativ AcinEqual Oppouniy Emoyer.

RESEARCH DEVELOPMENT ANDSENIOR SCIENTIST AWARDS

The National Zoological Park, Smithsonian Institu-tion (NZP) is expanding and diversifying its programs inwhole animal biology and offering two rotatng researchfellowships: the Research Development and Senior Sci-entist Awards. Preferred areas of interest are in evolu-tionary biology, animal behavior, physiological zoology,ecology, sociobiology, conscrvation biology, or veteri-nary sciences. Applicants whose interests complementthose of the NZP s current professional research staff willbe preferred. Each award will bc for a maximum of 3years. Stipcnds will bc commensurate with level andexperience. The Research Dcvelopmcnt Award is topermit mid-lvel scientists (at least 6years post-Ph.D.) tocomplete a major piccc of research m their specialty, aswell as to gain cxperience in research opportunitiesspecific to zoological parks. The Senior Scientist Awardis for distinguhed sacntists with significant researchcontributions. Timing of the Senior Scientist Award andits duration are flexible. The total duration of the ap-pointment cannot exceed 36 months, but it may bdivided into sevcral intervals, not less than 6 monthseach. Field research during the tenure of these fellow-ships is appropriate; however, fellows will be expected tobe primaril based at the NZP during their tenure so asto maximize their interactions and collaborations withzoo staff Applications should include a Statement ofInterest, and Outline of the Objectives and Significanceofthe proposed research and its relation to the mission ofthe NZP. Additionally, applicants should send a com-plete r6sumn, copies of their most significant publica-tions, and arrange for three letters of reference to beforwarded to: Dcvra G. Kleiman, Assistant Directorfor Rcseh, National Zoological Park, Washington,DC 20008, to whom additional inquiries should also bemade. Please specift for which award you are applying.Application deadline is 1 April 1988.

The Matcrials Science and Engineering Department ofthe University of Utah has available a number ofGRADUATE FELLOWSHIPS in its areas of special-ization. Thcse areas indude: ceramics, composite materi-als, polymeric materials, compound semiconductors ma-terials, chemical analysis of materials, and microwave andultrasonic characterization of materials. These fellow-ships provide $10,000 to $12,000 per year stipcnds. Forapplications and more information wnte:

Professor Joel B. DuBow, ChairmanMaterials Science and Engineering

2220 MEBUnivrsity of Utah

Salt Lake City, UT 84112The Univeniy ofUtah isanEqual Opportunity Employer.PLANT AND FUNGAL MOLECULAR BIOLO-

GY. Inquiries invited from qualified applicants forGRADUATE FELLOWSHIPS in: biochemistry, bot-any, or microbiology. Research areas indude: tuber,seed, and other plant proteins; electrophysiology ofmembrancs; aluminum toxicity; stress physiology (water,fieezing, pollution, and biotic) of temperate an tropicaltrees; molecular genetics of filamentous fungi (recombi-nant DNA, DNA-mediated transformation, and struc-ture and function of mating-type and developmentalgenes). Full tuition and stipe rite: Dr. Robert C.Ullrich, Department of Botany, Life Science Building, Universit of Vermont, Burlington, VT 05405.

POSTDOCTORAL RESEARCH FELLOW-SHIPS in psychoneuroimmunology are availablethrough an NIMHI Institutional Training Grant available1 July 1988 or later. This is an interdepartmental andmultidisciplinary program designed to providecourvsework and research experience in immunology forFellows trained in the behavioral or neurosciences and,conversely, to provide training in the neurosciences forFellows with abackground in immunology. The empha-sis is on research and Fellows may work with one ormore faculty from the Departments of Psychiatry, Neu-robiology and Anatomy, and Microbiology and Immu-nology m any of several aspects of brain, behavior,immune system interactions. P.D. and M.D. candidatesmust be citizens or permanent residents of the U.S. Two-year minimum. Send letter outlining goals and a briefdescription of research interests, curriculum vitae, andthe names of three references to: Robert Ader (Depart-ment of Psychiatry), David Flten (Department ofNeurobiology and Anatomy), or Nicholas Cohen

tof Microbiooy and Immunobgy), Uni-versity of Rochester Medical Center, Ro r, NY14642. Equal Opportu nity/AjiatveActin Employer.

PRE- AND POSTDOCTORALFELLOWSHIPS IN

RESPIRATORY BIOLOGYHARVARD SCHOOL OF PUBLIC HEALTHProgram areas include airway physiology and pharma-

cology, macrophage biology, respiratory muscles, mech-anisms of lung injury and environmental disease, andaerosol deposition and clearance. Appropriate back-grounds include physiology, cell biology, engineering, orother biomedical sciences. Women and minority candi-dat encouragcd. Please contact: Dr. Joseh Brain,Respiratory Biology Pgrm Harvard 3c ooofPublic Health, 66SHunt Avenuc, Boston, MA02115. Telephone: 617-732-1471.

PREDOCTORAL FELLOWSHIPSIN BIOMEDICAL ANDPHYSICAL SCIENCES

Biochemistry * Biology Biomathematics * Biomedi-cal Engineering * Biophysical Sciences * Biostatistics eChemistry * Computer Science 0 Cell Biology andAnatomy * Environmental Health * Epidemiology 0Genetics 0 Immunology * Materials Engineering 0M.D.-Ph.D. * Medical Genetics* MedicalcMicrobiology * Molecular Cell Biology* Neuroscience* Nutrition Sciences * Pathology * Pharmacology 0Physics * Physiological Optics * Physiology 0 PublicHealth * VirologyWell-funded faculty with diverse interests. Good post-

graduation placement record. Above-average stipendsindudc payment oftuition. Ready access to CRAY-XMPsupercomputer. Contact: The Graduate School (A),University ofAlabama at Birmin B inghamAL 35294; Tlephone: 205-934-246.EqualOpportu-nity:Affirative Action Instiuton.

SCIENCE, VOL. 239530

FELLOWSHIPS FELLOWSHIPS

PLANT BIOTECHNOLOGY

SogetalII

Sogetal, Inc. is launching avigorous program for the gen-etic engineering of cereals. Weare inviting well qualified andexperienced scientists in theareas of plant molecular biol-ogy and tissue culture to applyfor the key positions which willbe open in early 1988.Sogetal, located in theSan Francisco Bay Area, is aresearch center for ORSAN, thebiosciences division of LAFARGECOPPEE. We have developedleading technology for the hy-bridization of small grains, andhave an established programin cereal tissue culture.

We announce the followingopenings in our multidisciplinaryprogram:

Senior PlantMolecular Biologist(2 positions)The ideal candidates will havea PhD in a plant science withextensive hands on experiencein molecular biology includingvector construction, planttransformation, and geneexpression.Senior PlantTissue Culturist(1 position)The ideal candidate will have aPhD and at least 2 years of postdoctoral experience in a plantscience including a backgroundin the tissue culture of cerealswith a detailed knowledge ofregeneration and transforma-tion methods in monocots.

Candidates for all positionsshould have excellent commun-ication skills as well as super-visory experience.

Interested applicants pleasesend curriculum vitae to:Human Resources/MBPTSogetal, Inc.3872 Bay Center PlaceHayward, CA 94545

Equal opportunity employer

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Program Resources, Inc. (PRI) is atthe forefront of biomedical research,paving the way for new programs and

new discoveries at the NationalCancer Institute Frederick CancerResearch Facility, Frederick, MD. Weare looking for uniquely skilled pro-fessionals to direct existinglaboratories.

PRECLINICAL EVALUATIONLABORATORYThis laboratory supports the Biologi-cal Response Modifiers Program(BRMP) for which we are developingand using animal models to predictBRM anti-tumor activity. We are usingthis information to optimize protocolsfor the use of these agents in humanclinical trials. Additionally, efforts willbe made to evaluate new agents fortheir BRM activities in animal models.

CLINICAL MONITORING AND LAKLABORATORYThis laboratory also supports theBRMP for which we generate LAKcells to be used in patients for adop-tive immunotherapy trials in patientsreceiving various BRMs (interferons,tumor necrosis factors, colony-stimulating factors, monoclonal anti-

bodies). This is an excellent oppor-tunity for a clinically oriented scientistto be involved with design andimplementation of protocols forexperimental treatment of humancancer.

The scientists we seek should have aPhD or MD degree with proven expe-rience in the areas of immunologicaltesting and animal tumor modeling.Laboratory management experienceis also desirable.PRI will provide successful candi-dates with an excellent compensationand benefits package, including relo-cation assistance. For consideration,please send your resume and namesof three references to: PersonnelManager, Program Resources, Inc.,NCI-Frederick Cancer ResearchFacility, P.O. Box B, Frederick, MD21701. An equal opportunityemployer, M/F.

PROGRAMRESOURCES, INC.

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CONGRESSCARD1988 RESB~1~11~Sh5)SA

would like to receive information about:El Ares-Serono Symposia Congress Card

AJI the above CongressesElIn partcar the Congress on ............................................

O Ares-Serono Symposia Publications

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Pas send to Ares-Serono Symposia,Via Ravenna 8 - 00161 Rome- Italy

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