Personalized Medicine

Chokchai Jarusiripipat, M.D.Narinthorn Surasinthon, M.D.Thidakarn Rujipattnakul, M.D.

13 March 2013

• Integrated Medicine• Personal Health Management

(Dr.Narinthorn)• Personalized Medicine

(Dr.Thidakarn)

Patient Centered Care

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Samitivej Club Dr.Carebear SamitivejCharacter of kind,

healthy lifestyle bear

offer hospital information,

activities, news and promotions

Personalized social media

2555 สมาชกตอนสนป Facebook 15000 คน Twitter 48000 คน

• กจกรรมลดนาหนก และ สรางเสรมสขภาพผานทางทวตเตอร

– ใหคะแนนและทาโทษ เพอใหอาหารสขภาพดทกมอ ตามหลก healthy eating plate ของ harvard

– ฝกกลามเนอเพอลดสดสวนตามคลปทโพสให ทกวนเวลาสองทม

– ตดตามผลนาหนกตวรายสปดาหทกเชาวนเสาร

– รวบรวมผลนาหนกตว และ ภาพกอนหลง ตอนสนป

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หนงชด

ACCESSIBILITY AVAILABILITY

AFFORDABILITY

CONNECTED HOSPITAL

Concept

Long battery life and durable device

Premium smartphone with reasonable price

User friendly mobile screen to fit with BNH/Samitivej'scustomers

Conveniently connect to Personal Health Secretary and GPS tracking in emergency access

Phase1 : Patient Application

Main Page

4 APPOINTMENT

CONNECT

ORGANIZE

SUPPORT

5 APPLICATION SETTING

3 PERSONAL HEALTH SECRETARY

2 AMBULANCE

1 FAMILY & FRIENDS

6 MOBILE SITE

Emergency Call

Personal Health Secretary Call

Samitivej Remote Presence Model

Areas of ServiceAcute Care• Neurology• ICU• Trauma• Cardiology• Pediatric

Areas of ServiceChronic Care• Diabetes• Skin• Rounding (ICU)• Liver Center• Etc.

Personalized Medicine

A medical model that proposes the customization of healthcare – with medical decisions, practices, and/or products being tailored to the individual patient – such as by use of genetic or other informations

Genomics Landacape

Completion of Human Genome Project

Your Nightmare

Your Worse Nightmare

Your Worst Nightmare

Personalized medicines……..convert Pharmaceuticals

ToPharmasuitables

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“Era of personalised medicines… will

not be with us for at least another 15to 20 years”

Royal Society stated in 2005

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Pharmasuitables

Genetic Contribution to Complex Human Diseases

• Highly penetrant mutation are rare and account for less than 5%

• Majority result from large numbers of low-penetrance variants known as “Polymorphism”

• SNP (Single Nucleotide Polymorphism)– “Predisposition” genetic markers– NOT as disease causing genetic markers

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Benefits of SNPs Test

• Indicate earlier screening• Add motivation to make lifestyle

changes• Personalized lifestyle modification• Evaluate potential risks of serious

adverse drug reactions

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Customized Supplements

One size does not fit all

Customized Anti-Aging Tests

• Free radical• Total Antioxidants Capacity• Inflammatory markers• Cardiovascular risks markers• Vitamin and nutrition level• Hormones level

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Customized Supplements

Customized Life Style Modification

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Paradigm Shift

Today

DETECTAND

TREAT

Tomorrow

PREDICTAND

PREVENT

Lifestyle Medicine

Personalized Medicine

• Clinical Management• Service Management• Information Management

ชวตทประเสรฐ คอ ชวตททาใหคนรอบขางอยากทาความด

Those who lead the monastic life will inspire goodness in everyone.

วถวเวก