PERSONAL INFORMATION Family name, First name: Firat-Karalar, Elif Nur Date of birth: 23/08/1982 Nationality: Turkish URL for web site: https://mysite.ku.edu.tr/ekaralar EDUCATION University of California, Berkeley CA 12/2010 Ph.D., Molecular and Cell Biology Bilkent University, Ankara, Turkey 06/2004 B.S. with High Honors, Molecular Biology and Genetics CURRENT POSITION(S) Koç University, İstanbul, Turkey 06/2014- present Assistant Professor in Department of Molecular Biology and Genetics Research Topics: spatiotemporal regulation of centriole duplication cycle and ciliogenesis in cells, molecular

and functional characterization of centriolar satellites PREVIOUS POSITIONS Stanford University, Stanford CA 09/2011- 5/2014 Post-doctoral Scholar in Department of Biology Advisor: Dr. Tim Stearns Research Topics: identification of the centriole proteome, characterization of the spatial and temporal

interactions amongst centriole duplication proteins University of California, Berkeley, CA 08/2004-08/2011 Graduate Student in Dept. of Molecular and Cell Biology Advisor: Dr. Matthew Welch Thesis title: Dissecting the mechanism of Arp2/3 complex activation by actin filament binding and regulation

and function of JMY in cells Harvard Medical School, Boston, Massachusetts, MA 06/2003- 09/2003 Undergraduate summer fellow in Department of Microbiology and Molecular Genetics Advisor: Dr. Jon Beckwith Research Topic: Elucidation of alternative disulphide reduction pathways in E.coli using suppressor mutants University of Texas at Austin, TX 06/2002-09/2002 Undergraduate summer fellow in Dept. of Molecular Genetics and Microbiology Advisor: Dr. Philip Tucker Research Topic: Identification of the DNA binding consensus sequence of the transcription factor BCL11A FELLOWSHIPS AND AWARDS 2015 LOREAL UNESCO Women In Science Award 2015 TUBITAK 2236 Co-Funded Brain Circulation Scheme 2014 TUBITAK 3501 Career Development Award 2012-2014 NIH F32 Ruth Kirschstein post-doctoral fellowship 2007-2009 American Heart Association pre-doctoral fellowship 2004 UC Berkeley incoming graduate student travel award 2004-2007 Regents Fellowship, UC Berkeley 2000-2004 TUBITAK scholarship

2000-2004 Bilkent University full scholarship 2000-2004 Bilkent University High Honors student (8 semesters) 2000 Ranked in the top 200 of ÖSS among 1.5 million candidates 1999 Bronze Medalist in National Biology Olympiads in Biology 1997 Bronze Medalist in National Mathematics Olympiads in Biology SUPERVISION OF GRADUATE STUDENTS AND POSTDOCTORAL FELLOWS Deniz Conkar, Graduate Student, Koc University, 2014 Miranda Stratton, Graduate Student, Stanford University, 2014 Ariana Sanchez, Summer Intern, Stanford University, 2011 Peter Hsiue, Research Technician, University of California, Berkeley, 2010 Julia Chang, Graduate Student, University of California, Berkeley, 2009

TEACHING ACTIVITIES 2005 Cell Biology, Teaching Assistant, University of California, Berkeley 2006 Cell Biology, Teaching Assistant, University of California, Berkeley 2014 Life Sciences, Instructor, Koc University 2015 Life Sciences, Instructor, Koc University 2015 Cell and Molecular Biology of the Cytoskeleton, Instructor, Koc University INSTITUTIONAL RESPONSIBILITIES (if applicable) 2014 - present Faculty member, Koc University, Turkey 2014 - present Freshman Advisor for Molecular Biology and Genetics Department, Koc University,

Turkey 2014 - present College of Science, Molecular Biology and Genetics Department, Faculty Search

Committee, Koc University, Turkey MANUSCRIPT REVIEW 2015 Scientific Reports MEMBERSHIPS OF SCIENTIFIC SOCIETIES The American Society for Cell Biology (2008-present) Molecular Biology Association of Turkey (2014-present) MAJOR COLLABORATIONS Dr. Navin Rauniyar and Dr. John III Yates, Proximity mapping of centrosome duplciatoin proteins using BioID approach, Department of Chemical Physiology, The Scripps Research Institute, USA (2012-present) Kurt James Cox and Dr. Alice Ting, Application of APEX-based proximity mapping to the centrosome duplication factor PLK4, Department of Chemistry, Massachusetts Institute of Technology, USA (2013-present) CAREER BREAKS 2009 Maternity leave (3 months) 2011 Maternity leave (3 months)

Publications resulting from post-doctoral work:

Firat-Karalar, E.N., Stearns, T. (2014). Proximity interaction techniques to study the relationships among centrosome proteins. Elsevier’s Methods in Cell Biology. Accepted.

Firat-Karalar, E.N., Sante, J., Elliott, S, Stearns, T. (2014). Proteomic analysis of mammalian sperm cells identifies new components of the centrosome. J Cell Sci. Jul 29. pii: jcs.157008.

Firat-Karalar, E.N., Rauniyar, N., Yates, JR 3rd, Stearns, T. (2014). Proximity interactions among centrosome components identify regulators of centriole duplication. Curr Biol. 24(6): 664-670 (Google Scholar Citations: 12)

* Recommended by Faculty of 1000, http://f1000.com/prime/718304645

Firat-Karalar, E.N. and Stearns, T. (2014). The Centriole Duplication Cycle. Philos Trans R Soc Lond B Biol Sci. Sep 5; 369(1650). pii:: 20130460. (Google Scholar Citations: 3)

Publications resulting from graduate studies:

Firat-Karalar, E.N., Hsiue, P.P., Welch, M.D (2011). The actin nucleation factor JMY is a negative regulator of neuritogenesis. Mol Biol Cell. 22(23): 4563-4574 (Google Scholar Citations: 16)

Firat-Karalar, E.N. and M.D. Welch (2010). New mechanisms and functions of actin nucleation. Article in press. Curr Opin Cell Biol. 23(1): 4-13 (Google Scholar Citations: 93)

Goley E.D., Rammohan A, Znameroski E.A., Firat-Karalar E.N., Sept D, Welch M.D (2009). An actin-filament-binding interface on the Arp2/3 complex is critical for nucleation and branching stability. Proc Natl Acad Sci. 107(18): 8159-8164 (Google Scholar Citations: 23)

Selected seminar presentations:

Firat-Karalar, E.N., Rauniyar, N., Yates, JR 3rd, Stearns, T. (2014). Proximity mapping at the origin of centriole duplication. Invited Talk, Bogazici University, Turkey, 2014.

Firat-Karalar, E.N., Rauniyar, N., Yates, JR 3rd, Stearns, T. (2014). Beyond the parts list: Protein proximity mapping at the origin of centriole duplication. Poster Presentation, EMBO Centrosomes and Spindle Bodies Meeting, Lisbon, 2014.

Firat-Karalar, E.N. Proteomic analysis of mammalian sperm cells identifies new components of the centrosome. Invited Talk, UNAM National Nanotechnology Research Center, Turkey, 2014

Firat-Karalar, E.N. Proximity interactions among centrosome components identify regulators of centriole duplication. Selected talk, 3rd International Congress of Molecular Biology Association, Turkey, 2014

Firat-Karalar, E.N. Proximity interactions among centrosome components identify regulators of centriole duplication. Invited Talk, Stanford University Genetics Department Seminars, 2014

Firat-Karalar, E.N., Rauniyar, N., Yates, JR 3rd, Stearns, T. (2014). Beyond the parts list: Protein proximity mapping at the origin of centriole duplication. Poster Presentation, ASCB Annual Meeting, New Orleans, 2013.

Siripala, A.D., Goley, E.D., Znameroski, E.A., Firat, E.N., and Welch, M.D. Functional mapping of residues involved in Arp2/3 complex activation Poster Presentation, ASCB Annual Meeting, San Francisco, 2005.