Person-to-Person Microbial Diseases

• Airborne Transmission

• Respiratory Infections

• Human Reservoir• “Tough Microbes”• 10,000 -100,000

bacteria per sneeze

Streptococcus

• Streptococcus pyogenes

• S. pneumoniae

• Strep Throat

Other Strep Infections

• Group A Strep -GAS Hemolytic Strep.• Otitis media• Impetigo• Scarlet Fever• Rheumatic Fever• Pneumonia• GAS – Flesh eating ?

Diphtheria

• Corynebacterium diphtheriae

• Metachromatic Granules

• Pseudomembrane• Lysogenic

conversion• Toxoid vaccine

Whooping Cough

• Bordetella pertussis• DTaP Vaccine

– Diphtheria– Pertussis -acellular– Tetanus

Tuberculosis

• Mycobacterium tuberculosis

• Primary• Tuberculin Test• Post primary• Tubercules• Isoniazid

Other Mycobacterium spp

• M. bovis• Hansen’s Disease• M. leprae• Leprosy

Meningitis

• Neisseria meningitidis

• Meningococcus

• 30% carriers

• Other bacteria and viruses

Viral Respiratory Pathogens

• Common Cold• Rhinovirus• Influenza• Hemagglutinin• Neuraminidase

Antigenic Shifts

Polyvalent Vaccines

Other Viruses

• Red Measles• Rubeola• Mumps• German Measles• Rubella• MMR Vaccine

Chickenpox

Varicella

Shingles

Vaccine

Staphylococcus aureus

• Coagulase Positive• Boils• Impetigo• Toxic Shock

Syndrome

Gastric Ulcers

• Helicobacter pylori

• Discovered in 1983

• High carrier rate

• Robin Warren & Barry Marshall

• Nobel prize 2005

Hepatitis

• Liver Disease

• Hepatitis A

• People, food, water

• Hepatitis B

• Serum hepatitis

• Hepatitis C

• Cancer

Sexually Transmitted Diseases• Gonorrhea• Neisseria

gonorrhoeae• Syphilis• Treponema pallidum• Congenital Syphilis• Chancre• Secondary Syphilis• Tertiary Syphilis

Other STDs

• Chlamydia trachomatis

• Lymphogranuloma venereum

• Herpes simplex I • Cold sores• Herpes simplex II• Genital herpes

AIDS• Acquired

Immunodeficiency Syndrome

• HIV• Human

Immunodeficiency Virus

• CD4

•Reverse

Transcriptase• Protease

Inhibitor

Progression of HIV

P to P Diseases Word List

Airborne Transmission

Respiratory Infections

Streptococcus pyogenes

S. pneumoniae

Strept Throat

β Hemolysis

Otitis media

Impetigo

Scarlet Fever

Rheumatic Fever

Pneumonia

Staphylococcus aureus

Coagulase positive

Boils

Impetigo

Toxic Shock Syndrome

Diphtheria

Corynebacterium diphtheriae

Metachromatic Granules

P to P Diseases Word List 2

Pseudomembrane

Whooping Cough

Bordetella pertussis

DPT Vaccine

Tuberculosis

Mycobacterium tuberculosis

Primary

Tuberculin Test

Post primary

Tubercles

M. bovis

Hansen’s Disease

M. leprae

Leprosy

Viral Respiratory Pathogens

Common Cold

Rhinovirus

Influenza

Hemagglutinin

Neuraminidase

P to P Diseases Word List 3

Antigenic Shift

Polyvalent Vaccine

Measles (Red)

Rubeola

Mumps

MMR Vaccine

German Measles

Rubella

Chickenpox

Varicella

Shingles

Sexually Transmitted Diseases

Gonorrhea

Neisseria gonorrheae

Syphilis

Treponema pallidum

Congenital Syphilis

Chancre

Secondary Syphilis

Tertiary Syphilis

P to P Diseases Word List 4

Chlamydia trachomatis

Lymphogranuloma venereum

Herpes simplex I & II

Acquired Immunodeficiency Syndrome

Human Immunodeficiency Virus

CD4

Reverse Transcriptase

Protease Inhibitors