Peptic UlcerPeptic UlcerBy: Allicia KwakyeBy: Allicia Kwakye

Miss TranMiss Tran

TPJ-3MOTPJ-3MO

What is Peptic UlcerWhat is Peptic Ulcer Ulcer occurs in the gastrointestinal tractUlcer occurs in the gastrointestinal tract

It is acidic and very painfulIt is acidic and very painful

It caused by a spiral shaped bacterium that lives It caused by a spiral shaped bacterium that lives within the acidic area of the stomachwithin the acidic area of the stomach

Ulcers can developed or worsened by drugs such Ulcers can developed or worsened by drugs such asas Aspirin Aspirin..

Peptic Ulcer emerges frequently in the duodenum Peptic Ulcer emerges frequently in the duodenum rather than the stomach.rather than the stomach.

DuodenumDuodenum is the first part of the small intestine is the first part of the small intestine

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The CauseThe Cause Chronic inflammation due to the Chronic inflammation due to the Helicobacter pylori.Helicobacter pylori. It colonizes It colonizes

the the antral mucosaantral mucosa..

The bacterium can cause a chronically active gastritis. ( type B), The bacterium can cause a chronically active gastritis. ( type B), resulting in a defect by the resulting in a defect by the gastrin produce by that part of the stomach.

NSAIDs such as ibuprofen penetrates the lining of the stomach and releases substances that damages cells.

NSAIDs also blocks the natural chemicals (Prostaglandins) that helps and repair those cells.

Chronic stress is strongly associated in the risk of developing Peptic Ulcer

A combination of chronic stress and irregular meal time is significant to this risk of developing Peptic Ulcer.

Also spicy food and alcohol is a risk for developing Peptic Ulcer.

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SymptomsSymptoms Gnawing or burning pain in the abdomen. This occurs between the Gnawing or burning pain in the abdomen. This occurs between the

breast bone and navel, it is often by pass as a “heartburn”. breast bone and navel, it is often by pass as a “heartburn”.

Bleeding from the Peptic Ulcer.Bleeding from the Peptic Ulcer. - Is present during vomiting or in the stool - Is present during vomiting or in the stool

(black stool).(black stool).

You may experience these symptoms soon after meals:You may experience these symptoms soon after meals:– PainPain– NauseaNausea– Pain that radiates to the backPain that radiates to the back– Unusual weaknessUnusual weakness– Unintended weight lossUnintended weight loss

TreatmentTreatment

A combination of antibiotics and acid reducing medication A combination of antibiotics and acid reducing medication such as:such as:– Proton Pump Inhibitors.Proton Pump Inhibitors.– Esomeprazole,Esomeprazole,– PantoprazolePantoprazole– RabeprazoleRabeprazole

Antibiotics: Antibiotics: – ClarithromycinClarithromycin– AmoxicillinAmoxicillin– MetronidazoleMetronidazole

They all should be take twice per day.They all should be take twice per day.