Paul Richard Carney, M.D. - University of Florida...University of Florida College of Medicine and...
Transcript of Paul Richard Carney, M.D. - University of Florida...University of Florida College of Medicine and...
CURRICULUM VITAE
January 2011
Paul Richard Carney, M.D.
Current Position
Professor of Pediatrics and Neurology
Joint Professor of Neuroscience and Biomedical Engineering
Wilder Chair for Research in Epilepsy
Chief of the Division of Pediatric Neurology
Director of the Comprehensive Pediatric Epilepsy Program
Attending Pediatric Neurologist Shands Children’s Hospital
University of Florida College of Medicine and McKnight Brain Institute
Gainesville, Florida, U.S.A.
Address
Department of Pediatrics
Division of Pediatric Neurology
University of Florida College of Medicine
JHMHC, Room HD-410, Box 100296
Gainesville, Florida, USA 32610
Phone: 352-273-9328
Fax: 352-392-9802
Email: [email protected]; [email protected]
Websites: http://www.neurology.peds.ufl.edu/carneylab/index.htm
http://www.neurology.peds.ufl.edu
Research laboratory:
Biomedical Science Building Room J383
University of Florida, Gainesville, FL 32610
Synopsis
Paul R. Carney, M.D., Professor and Chief of the Division of Pediatric Neurology at the
University of Florida College of Medicine since 2003 and a full-time member of the Department
since 1998. He holds the Wilder Chair Professor in Epilepsy, is Director of the University of
Florida Comprehensive Pediatric Epilepsy Center, and Professor of Pediatrics and Neurology. He
is Graduate Faculty and Joint Professor in Neuroscience and Biomedical Engineering.
As Director of the Pediatric Neurology at the University of Florida, Dr. Carney has led the
department to become one of the top pediatric neurology divisions in the United States and a
national leader in epilepsy. He initiated comprehensive new programs addressing physician and
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scientist development. His efforts led to more than $10 million in federal funding to support
translational neuroscience and biomedical engineering research, and $6 million in philanthropic
funds to carry forward the research and educational missions.
Dr. Carney is an internationally recognized expert in the diagnosis and treatment of children
and adults with neurological disorders. His research has focused on the development of novel
diagnostic methods and more effective treatments for children and adults with epilepsy. He has
authored more than 300 articles, abstracts, books, and book chapters. He is a Fellow of The
American Neurological Association and The American Pediatric Society, honors bestowed on
clinical scientists in academic medicine whose accomplishments are deemed of high importance
and scientifically distinguished.
Dr. Carney has received 10 years of continuous funding support from the National Institutes
of Health, National Science Foundation, and Department of Defense for basic neuroscience and
neuroengineering research in epilepsy. Epilepsy is the third most prevalent neurological disorder
affecting more 50 million people worldwide. More than one-third of individuals with epilepsy
are refractory to current therapies. Dr. Carney has been awarded the University of Florida Faculty
Research Prize in Clinical Sciences, the highest honor offered by the University of Florida
College of Medicine, for his major and significant contributions to medical research. He was also
recognized for his teaching excellence with the University of Florida Department of Pediatrics
Teaching Excellence Award. He has authored three of the leading textbooks in Pediatric
Neurology, Epilepsy and Neurophysiology, and Sleep Medicine, and serves on three major
editorial boards - Computers in Biology and Medicine, Recent Patents on Biomedical
Engineering, and Journal of Pediatrics. Dr. Carney received his MD from the University of
Valparaiso School of Medicine. He completed his residency in pediatrics at Case Western
Reserve University - Rainbow Babies and Children’s Hospital in Cleveland Ohio, followed by
fellowships in Pediatric Neurology, Epilepsy and Clinical Neurophysiology, and Sleep Medicine
at The University of Michigan in Ann Arbor Michigan.
Education
High School: 1970-74 Chardon High School, Chardon, OH
Undergraduate: 1974-79 John Carroll University, University Heights, OH
Bachelor of Science
Graduate: 1982-90 University of Valparaiso College of Medicine
Doctor of Medicine (with honors)
Clinical Training
1992-94 Pediatric Internship and Residency
Case Western Reserve University: Department of Pediatrics
Rainbow Babies and Children’s Hospital, Cleveland, OH
Program Director: Robert Kliegman, M.D.
1994-96 Pediatric Neurology Fellowship
University of Michigan Medical Center
Departments of Pediatrics and Neurology, Ann Arbor, MI
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Program Director: Gihan Tennekoon, M.D.
1996-98 Neurophysiology and Clinical Epilepsy Fellowship
University of Michigan Medical Center
Department of Neurology, Ann Arbor, MI
Program Director: Ivo Drury, MBBCh
1997-98 Sleep Disorders Fellowship
University of Michigan Medical Center
Department of Neurology, Ann Arbor, MI
Program Director: Michael Aldrich, M.D.
Research Training
1981-83 Research Associate
Case Western Reserve University
Department of Neuroscience
Advisor: Jerry Silver, Ph.D., Raymond Lasek, Ph.D.
Area: Axon guidance during early peripheral auditory nerve development
1990-92 Post Doctoral Research Associate
University of Valparaiso: Cell Biology Department
Primary advisor: Professor Doctor Eduardo Couve
Area: Axon guidance and neuronal cell migration during early avian peripheral
auditory system development
Academic Appointments
1998-05 Assistant Professor of Pediatrics
University of Florida Department of Pediatrics
Gainesville, FL
1998-05 Adjunct Assistant Professor of Neurology
University of Florida Dept of Neurology
Gainesville, FL
2000- Graduate Faculty
University of Florida Graduate School, Colleges of Medicine, Engineering
Health Professions, Food and Nutrition Sciences, and Education
Gainesville, FL
2001-05 Affiliate Assistant Professor of Neuroscience
University of Florida Department of Neuroscience
Gainesville, FL
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2004-05 Affiliate Assistant Professor of Biomedical Engineering
University of Florida Department of Bioengineering
Gainesville, FL
2006-07 Associate Professor of Pediatrics and Neurology
University of Florida Departments of Pediatrics and Neurology
College of Medicine
Gainesville, FL
2007- Professor of Pediatrics and Neurology
University of Florida Departments of Pediatrics and Neurology
College of Medicine
Gainesville, FL
2007- Joint Professor of Biomedical Engineering
University of Florida Dept of Biomedical Engineering
College of Engineering
Gainesville, FL
2007- Affiliate Professor of Neuroscience
University of Florida Neuroscience Department
College of Medicine
Gainesville, FL
Administrative Appointments
1999- Medical Director
Comprehensive Pediatric Epilepsy Program
Neurodiagnostics Laboratory
University of Florida Health Center
Gainesville, FL
2001-02 Interim Division Chief
Division Pediatric Neurology
University of Florida Department of Pediatrics
Gainesville, FL
2002- Division Chief
Division of Pediatric Neurology
University of Florida Dept of Pediatrics
Gainesville, FL
2007- Director
Wilder Center for Epilepsy Research
University of Florida College of Medicine
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Gainesville, FL
Hospital Appointments
1998- Attending Pediatric Neurologist
University of Florida/Shands Children’s Hospital
1998- Medical Staff in Child Neurology
University of Florida/Shands Children’s Hospital
1998- Pediatric Epilepsy & Clinical Neurophysiology Staff Physician
University of Florida/Shands Children’s Hospital
1998- Pediatric Sleep Medicine Staff Physician
University of Florida and Shands Children’s Hospital
Honors
1980 Diamond-Shamrock Corporation Cooperative Educational Scholarship, Cleve, OH
1980 John Huntington Scholarship for Undergraduate Studies, John Carroll University
1985 National Research Service Award, National Science Foundation (Neuroscience)
1990 Doctor of Medicine (with Honors), University of Valparaiso College of Medicine
1998 Fellow of the American Academy of Pediatrics
1999 Teaching Excellence Award, Dept of Pediatrics, University of Florida
2000 Honorary Fellow of the Society for Pediatric Research
2004 William Pierskalla Best Paper Award
2004 Wilder Epilepsy Research Chair, University of Florida College
2006 Honorary Member, Chilean Child, Adolescent Psychiatry, & Neurology Society
2006 Tenure, University of Florida College of Medicine
2008 Wilder Chair Professor, University of Florida College of Medicine
2008-10 Best Doctors in America Honorary Award
2009 Faculty Research Prize in Clinical Science for Outstanding Achievements and
Productivity Research, University of Florida College of Medicine
2010 American Neurological Association – Elected Member
2010 American Pediatric Society – Elected Member
Certifications
Ohio Medical State License
Michigan Medical State License
Florida Medical State License
American Board of Neurology and Psychiatry, Inc. with Special Competence in Child Neurology
Non-Tenure and Entrepreneurial Activities
1980-81 Research Chemist
Diamond Shamrock Corporation: Cleveland, OH
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2005-07 Scientific Medical Director
Optima Neuroscience, Synogen Group, Gainesville, FL
Real-time brain function monitoring software development
2007- President
Chronobionics, LLC, Gainesville, FL,
Closed-loop seizure prevention device development
http://www.chronobionics.com
Memberships and Offices in Professional Societies
American Academy of Pediatrics
Federation of American Societies for Experimental Biology
University of Florida, McKnight Brain Institute
American Epilepsy Society
Russell N De Jong Society, University of Michigan
American Sleep Disorders Society
American Academy of Neurology
Alachua County Medical Society
American Association for the Advancement of Science
Biomedical Research Partnership for Brain Dynamics, University of Florida
Society for Pediatric Research, American Academy of Pediatrics
University of Florida, Child Research Institute
Center for Optimization, College of Engineering, UF of Electrical Engineering and Electronics
Child Neurology Society Active Member
American Academy of Neurology Scientific Sleep Abstracts Reviewer
Society for Neuroscience
Fund Raising Activities
Endowment: B.J. and Eve Wilder Endowment for excellence in epilepsy research $ 2M gift
(+$2M state match) 2005
Endowment: B.J. & Eve Wilder Professorship $ 800,000 (+$ 500,000 state match) 2007
Endowment: Damiano Gift for research in stuttering $ 1M gift (+$1M state match), 2007
Scientific Activities
Current Editorial Board Positions
2005- Editorial Board, Computers in Biology and Medicine
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2007- Editorial Board, Recent Patents on Biomedical Engineering
2007- Editorial Board, The Journal of Pediatrics
Current Journal Reviewer Activities
1998- Pediatric Neurology
Epilepsia
Journal of Child Neurology
1999- Journal of Clinical Neurophysiology
2002- Lippincott Williams and Wilkins Publishers
Psychosomatic Medicine
Basic and Clinical Pharmacology & Toxicology
ACTA Neuropsychiatrica
2004- Sleep
2004- Experimental Medicine and Biology Society IEEE
2004- Clinical Pediatrics
2005- Epilepsy and Behavior
2005- Computers in Biology & Medicine
2007- Journal of Pharmacology & Experimental Therapeutics
2007- Journal of Pediatric Neurology
2007- American Academy of Neurology (Sleep Section)
2007- The FASEB Journal
2008- Journal of Pediatric Neurology IEEE Transactions on Biomedical Engineering
American Academy of Neurology Scientific Abstract Reviewer
2009- EURASIP Journal on Advances in Signal Processing
Chaos
2010- Journal of Neural Engineering
Grant Reviewer
1999 American Epilepsy Society
2000- University of Florida, Division of Sponsored Research
2000- Canadian Research Council
2007- NIH Study Section: Member, ZRG1 ETTN-E 10 B, Clinical Neurophysiology,
Devices, and Neuroprosthetics, Panel on 6/07, 09/07, 02/08, 06/08, 10/08, 03/09
2007- Graduate Student for Outstanding Research, Office of Graduate Education, Office of
the Dean, College of Medicine, University of Florida, Gainesville, FL
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2007- Natural Sciences and Engineering Research Council of Canada
2008- NIH Study Section, Member, Neurotechnology Study Section Emerging Technologies
and Training Neurosciences Integrated Review Group, 10/08, 02/09
University of Florida Division of Sponsored Research, Research Opportunity Fund
2010- NIH Study Section Co-Chair: Member, SBIR ETTN-K 10, 02/10
NIH Study Section, Emerging Technologies and Training in Neurosciences IRG
03/10
NIH Study Section, Small Business: Clinical Neurophysiology, Devices, Auditory
Devices and Neuroprothesis. 2010/10 ZRG1 ETTN-K (10) B 06/24/2010-06/25/2010
Consulting Activity
1999-01 Cephalon, Inc.
2001- Glaxo Smith Klein, Inc.
2001-02 UCB Pharma
2002- Lippincott Wilkins and Williams Publishers
2003- Novartis, Inc.
2006 Sanofi Aventis, Inc.
2007 Greenley Associates
2008 Foresight Science & Technology, Inc.
2009- Cyberonics, Inc.
Teaching Activities
1997-98 Invited Lecturer, Neurology resident’s neuroscience lecture series, University Michigan, Ann Arbor, MI
1998- Teaching attending physician, Pediatric Neurology Series Dept of Neurology,
University of Florida
In-patient teaching attending, Pediatric Neurology, University of Florida
Out-patient teaching attending, Ped Neurology, Epilepsy/Sleep Disorders Clinic, University of Florida
Lecturer, Neonatal Fellows Seminar Conf, Div of Neonatology, Dept. Pediatrics, University of Florida
General pediatrics morning conference attending, Dept. of Pediatrics, University of Florida
Lecturer, Pediatric Neurology Morning Conference, Dept. of Pediatrics, University of Florida
Lecturer, Epilepsy, Clinical Neurophysiology, and Sleep Medicine, UF Dept Neurology
1999- Oral examiner, second year medical students, UF College of Medicine
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2001- Teaching Preceptor, Biomedical Engineering, University of Florida, BME 6010
Clinical Shadowing Course, University of Florida College of Engineering
2004- Lecturer, Neuroscience course GMS6007, UF Department of Neuroscience
Member, Neurology Residency Advisory Committee, UF Department of Neurology
Lecturer, Neuroscience course GMS 6007, UF Department of Neuroscience
2005- Faculty Preceptor, MEL 4012 Undergraduate Physician Shadowing Program
2007- Lecturer, Physiology Graduate Level Course, UF Dept Biomedical Engineering
Courses Developed and Taught
2005- Biomedical Engineering BME 6010, Credit 3, Title, Clinical Preceptorship, Department Bioengineering, University of Florida College of Engineering, Summer, Fall, Spring Semesters, 20-30 students per semester.
University of Florida Graduate Student Activities
Doctoral Dissertations Committees: Chair/Co-Chair
2000-03 Sobha Fritz, Department of Child Psychology
Thesis: Maternal-child adherence in childhood epilepsy
Current position: Faculty, Emory University, Atlanta, GA
2001-05 Greg Selke, Department of Neuropsychology, College of Health Professions
Thesis: Emotional Reactivity to Picture Stimuli in Children in Children with and
without Attention-Deficit/Hyperactivity Disorder
Current position: Faculty, Brown University, Providence, RI
2001-04 Danielle Becker, Department of Neuropsychology
Thesis: Relation between sleep and epilepsy in children
Current position: Neurology resident, University of Pennsylvania
2002-06 Sandeep Nair, M.S., Dept of Bioengineering, College of Engineering
Thesis: Quantitative EEG signal analysis in rat limbic epilepsy model
Post Doc: Allegheny Universtiy, Pittsburg, PA
2003-08 Susan Bongiolatti, Department of Neuropsychology
Thesis: Frontal lobe dysfunction in childhood epilepsy & cognitive problems in
children with sleep disorders and epilepsy
Current position: Faculty, Case Western Reserve University, Cleveland, OH 2006-10 Rabia Zafar, Department of Neuroscience
Topic: Epilepsy gene therapy
2006-10 Mansi Parekh, Interdisciplinary Program, Department of Neuroscience
Topic: MRI and epileptogenesis in an animal model of limbic epilepsy
Current position, Post Doc University of Florida, Gainesville, FL
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2007-09 Jason Winters, Department of Biomedical Engineering
Topic: Real-time brain monitoring
Current position: Industry, Charlottesville, VA
2007-10 Stephen Meyers, Department of Biomedical Engineering
Topic: Closed-loop seizure prevention
Current position: Post Doc, University of Florida, Gainesville, FL
2008- Svetlana Kantorovich, Interdisciplinary Program, Department of Neuroscience
Topic: Convection enhanced drug delivery in epilepsy
2009- Francisco Delgado UF College of Engineering, Dept of Biomedical Engineering
Topic: Nanotechnology and epilepsy
Graduate Student Committee Member
1998-99 Jodi Passman, UF Department of Food and Agricultural Science
Thesis: Ketogenic diet and epilepsy
2000-01 Tran Ai Hang, UF Department of Food and Agricultural Science
Thesis: Ketogenic diet efficacy in epilepsy
2003-08 Anil Bollimunta, UF Dept of Biomedical Engineering, College of Engineering
Thesis: Techniques for analysis of neural activity: spontaneous and evoked
2003-05 Mandy Layman, UF Department of Food Science
Thesis: Ketogenic diet in intractable childhood epilepsy
2004-08 Chang-Chia Liu, UF Dept of Biomedical Engineering, College of Engineering
Thesis: Brain dynamics, system control and optimization techniques with
application in epilepsy
2005-08 Alex Cadotte, UF Dept of Biomedical Engineering, College of Engineering
Thesis: Non- linear dynamics for discrimination of pharmaceutical agents
on MEA's
2007-08 Nicole Nasewicz-Pies, UF Dept of School Psychology, College of Education
Thesis: Recognizing, differentiating, and referring students with absence
seizures: what factors affect pre-service teachers’ decision-making?
2007-08 Chelsey Durgin, UF Biomedical Engineering Dept,
Topic: Diffusion Tensor Imaging and Epilepsy
2006-08 Hector Selpulveda, UF Department of Biomedical Engineering
Topic: MRI and epilepsy
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2006-10 Mamta Wankhede, UF Department of Biomedical Engineering
2006-10 Mackenzie E. Hoffmann, UF Interdisciplinary Program, Dept of Neuroscience
Topic: Expanding the role of cannabinoids in the synaptic physiology of the
hippocampus
2008-10 Adam D. Fletcher, UF Department of Biomedical Engineering
Topic: A computational study of flow and mass transport in intrathecal drug
delivery
2007- Phil Barish, UF Department of Biomedical Engineering, College of Engineering
Topic: Optogenetics and epilepsy
2009- Katherine Follansbee-Junger, UF Department of Neuropsychology
Topic: Examining the contribution of health behaviors and psychological
functioning I anti- epileptic drug induced weight gain among children with
epilepsy.
2010- Jigesh Dalal, UF Department of Biomedical Engineering
Clinical Pre-Medical Research
2000-01 Scott Palmer, University of Miami Medical School
2000-01 Tang Tran, University of Florida College of Medicine
2001-02 Jonathan Day, Uniformed Services University
2002-03 Meadow Maze, University of Arizona
2002 Ryan Asdourian, University of Florida
2007-08 Angela Brown, University of Florida
2007-09 Richard Schatz, Washington University
2008 Kathryn P. Helmick, University of Florida
Post-Doctoral Fellows Supervised
2003-08 Wendy Norman, D.M.V., Ph.D.
Project title: Seizure Prediction in the Rat Chronic Limbic Epilepsy Model
Current position: Faculty, University of Florida Dept Veterinary Medicine
2004-06 Justin C. Sanchez, Ph.D.
Project title: Hybrid Brain Machine Interface in Epilepsy
Current position: Faculty, University of Miami Dept Biomedical Engineering
2005-07 Greg Selke, Ph.D.
Project title: Relation between Sleep Disorders and ADHD
Current position: Faculty Brown University, Providence, RI
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2006-09 Sachin Talathi, Ph.D.
Project title: Evolution into Epilepsy, Epilepsy Chronobiology
Current position: Faculty, University of Florida
2007-08 Dan Tarquinio, D.O, Research Neurology Fellow
Project: Rett Syndrome
(Co-Mentor’s Dr. Alan Percy, UAB, Dr. Dan Driscoll, UF
Current position: Neurology fellow, Boston University, Boston, MA
Current Post-Doctoral Fellows
2008- Alex Cadotte, Ph.D.
Project title: Effective Connectivity and Epilepsy
2008- Junli Zhao, M.D., Ph.D.,
Project title: Place cells activity in epilepsy
2009 Mansi Parekh, Ph.D.
Project title: Structural analysis in epilepsy
2009 Rabia Zafar, Ph.D.
Project title: Gene therapy in epilepsy: somatostatin and channel rhodopsins-2
Clinical Fellows Supervised
1998-99 Terry Bunch, M.D., Fellowship in Pediatric Neurology
2000-01 Brenda Wu, M.D., Ph.D., Fellow in Clinical Neurophysiology
2003-04 George Gacibieu, M.D., Fellow in Clinical Neurophysiology
Advisor to Pediatric Residents
1999- Advisor/Mentor Program, first-year medical students
2003-04 Liliana Petrova, M.D., Pediatric resident
Faculty Medical Student Advisor
2007-09 Richard Schatz Epilepsy animal models Medical Student, University of Florida
2008 (Summer) Advisor: Jenny Wilkerson, MSRP Fellowship (Summer, 2008)
Project: Relationship between sleep disturbance and daytime behavioral
problems in children with epilepsy
2008-09 Kathryn Helmick Epilepsy animal models Medical Student, UF
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2010 (Summer) Yeong Jung Park College of Medicine Medical Student Research Program,
Identifying Structural and Functional Correlates in Children and Adults with
Medically Intractable Epilepsy, Medical Student, University of Florida
College of Medicine
Local Committee and Administrative Services
1998 Biocomputing 2001, University of Florida, College of Engineering
1998 Conference Co-Organizer for Quantitative Neuroscience: Models, Algorithms,
Diagnostic and Therapeutic Applications Conference University of Florida
1998- University of Florida, EEG & Epilepsy Monitoring Unit Planning Committee Shands
Children’s Hospital
2000 University of Florida, Sleep Disorders Program Planning Committee
2000-03 Department of Pediatrics Strategic Planning Committee
2000-04 Department of Pediatrics Outpatient Clinic Planning Committee
2000 University of Florida Sleep Disorders Program Planning Committee Shands
Children’s Hospital
2001 Quantitative Neuroscience/Neural Engineering Seminar, University of Florida
McKnight Brain Institute, Weekly Seminar Fall & Spring Semesters
2001 Epilepsy Services of Florida
2001 NIH sponsored “Brain Dynamics Biomedical Partnership
2001 Co-Coordinator, Quantitative Neuroscience/Neural Engineering Seminar University
of Florida McKnight Brain Institute.
2002 Quantitative Neuroscience: Models, Algorithms, Diagnostic & Therapeutic
Applications, Univ. Florida
2003 Department of Neurology Epilepsy Faculty search committee, University of Florida
Division of Critical Care Faculty search committee, Dept of Pediatrics, University of
Florida
2003 Data Mining in Biomedicine, University of Florida, College of Engineering and
McKnight Brain Institute
2003 Quantitative Neuroscience/Neural Engineering Seminar Graduate Course in
Biomedical Engineering, University of Florida College of Engineering and McKnight
Brain Institute
2003 Dept of Bioengineering Faculty Search Committee, University of Florida College of
Engineering 2004-05
2003 University of Florida McKnight Brain Institute Director search committee
2003 Conference Co-organizer, Quantitative Neuroscience: Models, Algorithms,
Diagnostic and Therapeutic Applications Conference, University of Florida
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2003-08 Medical Advisor to NICA, Tallahassee, FL State of Florida
2004-05 Advisory Board, Data Mining in Biomedicine, UF College of Engineering
2004- Center for Applied Optimization, University of Florida, College of Engineering and
McKnight Brain Institute
2004-07 Search Committee for Department of Biomedical Engineering, University of Florida
College of Engineering
2005- Academic Graduate Committee, Dept of Biomedical Engineering, University of
Florida College of Engineering
2005 Co-Organizer, Conference on Systems Analysis, Data Mining, and Optimization in
Biomedicine, University of Florida Feb. 2-4, 2005
2005 Ad Hoc Advisory Board Member, Dept. Biomedical Engineering, College of
Engineering, University of Florida (May, 2005)
2005 Scientific Judge, Lincoln Middle School Science Fair, Gainesville, FL, Feb, 05
2006 Advisory Board, DIMACS Workshop on Data Mining, Systems Analysis, and
Optimization in Neuroscience, University of Florida, Gainesville, FL,
2006 Advisory Committee, Conference on Data Mining, Systems Analysis and
Optimization in Neuroscience February 15-17, 2006. University of Florida
2008 University of Florida College of Medicine Neurology Chair search committee
2009 University of Florida College of Medicine M.D./Ph.D. Program
National Committee and Administrative Services
1998 Platform Moderator, American Epilepsy Society
2001- Committee Member, American Epilepsy Society, Special Interest Group
2005 Invited Guest, National Science Foundation, Collaborative Research Computational
Neuroscience, Bethesda, MD, March, 05
2007-08 Member, American Epilepsy Society Scientific Program Committee
2008 Sleep Abstracts Reviewer, American Academy of Neurology
2008 Scientific Abstract Reviewer, American Epilepsy Society Annual Meeting
2008-12 Member, American Epilepsy Society Scientific Program Committee
2008 Scientific Abstract Reviewer, American Academy of Neurology 61th Annual Meeting
2008 Advisory Board, College of Engineering Department of Biomedical Engineering
University of Florida, October 16-17, 2008
2008-09 Member of the Advisory Committee, Fourth International Workshop on Seizure
Prediction spring, 2009
2009 Scientific Abstract Reviewer, American Academy of Neurology 61th Meeting
2009-12 Member, Pediatric Content Committee, American Epilepsy Society
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2010 Co Chair, American Academy of Neurology's Science Committee and Scientific
Program Subcommittee, S04: Sleep Disorders, April 13, 2010, 62nd
Annual Meeting
of the American Academy of Neurology, April 10 to April 17, Toronto
2010 Chair, Clinical Epilepsy Nanosymposium, Society for Neuroscience, November 14,
2010, San Diego, CA
Patents, Patent Invention Disclosures and Copyrights
1. Real-Time Brain Monitoring System
Inventors: Paul R. Carney, MD, J. Chris Sackellares, MD, Deng Shaiu, Ph.D.
UF Provisional Patent UF#-11220
2003
2. Multi-Dimensional Multi-Parameter Time Series Processing for Seizure Warning &
Prediction
Inventors: J. Chris Sackellares, MD, Paul R. Carney, MD Type: Provisional Patent UF#-No
028724-143
2003
3. Closed-Loop Micro-Control System for Predicting and Preventing Epileptic Seizures
Inventors: Justin Sanchez and Paul R. Carney
UF Provisional Patent UF#- 63815P(49163)
2005
4. Real-Time Brain Monitoring System,
Inventors: Paul R. Carney, MD, J. Chris Sackellares, MD, Deng Shiau, Ph.D. Type:
Provisional Patent UF#-#-11220
February 25, 2005
5. Interactive Dynamical Brain Monitoring and Neuro Diagnostic Systems
Inventors: Sackellares JC, Carney PR, and Shiau DS. (Attorney Docket No. 028724-
144.001United States Patent Application Number 11/065,703).
UF Provisional Patent UF
February 25, 2005
6. State Dependent, Direct and Model-based Closed-loop Seizure Control System
Inventors: Sackellares JC, Principe JC, Shiau DS, Pardalos PM, Carney PR, Cho J, Nair SP
Suharitdamrong W and Dance LK.
UF invention disclosure # – 11926.
2005
7. Neuromodulation of Excitation and Inhibition to Control Epilepsy and Neurological
Disorders
Inventors: Ditto, WL, Carney PR, Talathi S, Hwang, DU.
UF Invention disclosure UF # 12785
February 11, 2008
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8. Real-Time Brain Monitoring System
Inventors: Paul R. Carney, J. Chris Sackellares, Deng Shaiu
Patent Number 7433732
October 7, 2008
9. Magnetic Resonance Compatible and Susceptibility-Matched Apparatus and Method for MR
Imaging and Spectroscopy
Inventors: Thomas Harold Mareci, Paul Richard Carney, Garrett William Astary and Hector
Sepulveda
Application Number 61/232,288
August 7, 2009
10. Optically Active Opioid Receptors for the Treatment of Chronic/Acute Pain
Inventors: William Ogle and Paul R. Carney
Application Number 13317
2009
11. Detecting Epileptogenesis
Inventors: Sachin S. Talathi, Paul R. Carney, Dong-Uk Hwang, William L. Ditto
Attorney Docket No.: 450-P0005US
November, 2010
GRANT SUPPORT
Current Research Grant Support
Title: CRNCS: Evolution into Epilepsy
Agency: NIH R01-EB004752-01
Dates: 09/01/04 – 06/30/10
Effort: 1.8 calendar
Role: MPI
Direct: $1,287,170
Summary: The basic project goals are to use our computational algorithms and models to
evaluate potential hypothesis on the underlying functional and structural mechanisms of
epileptogenesis in a validated animal model of temporal lobe epilepsy.
Title: CRCNS: Automatic Prediction of the Onset of Epilepsy via Analysis of High Angular
Resolution Diffusion MRI
Agency NIH NIBIB R01 EB007082-02
Dates: 08/01/06 to 05/31/10
Effort: 1.2 calendar
Role: MPI
Direct: $1,296,877
Summary: The major goals of this study are to develop a computational algorithm for MR high
angular resolution diffusion imaging de-noising and estimation of the field of probability
densities. Then to develop and validate an atlas-based segmentation scheme that allows
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computation of fiber tracts and the signature of structural changes, during the period of
epileptogenesis, and predict the time of onset of epilepsy.
Title: Computational Transport Models for Convection-Enhanced CNS Delivery
Agency: NIH R01 NS063360
Dates: 07/01/08 to 07/31/13
Effort: 1.2 calendar
Role: MPI
Amount: $1,505,597
Summary: The goal of this study is to provide a fundamental understanding of convection
enhanced delivery of compounds into the hippocampus for the treatment of temporal lobe
epilepsy.
Title: Balanced Polyvalent Anti-Glutamatergic Action as a Novel Approach to Efficacious
Neuroprotection
Agency: NIH R21 NS060862-01A1 (Martynyuk, A)
Dates: 2008 to 2010
Role: Consultant
Summary: This study tests the hypothesis that in newborn rats, anesthetics that enhance GABA
A/glycine receptor activity may depolarize the neuronal membrane potential, trigger seizures, and
cause neurotoxicity.
Title: Photoacoustic Tomography of Epilepsy
Agency: Congressionally Directed Statement Medical Research Programs (USAMRMC)
Department of Defense ASDRP, Department of the Army
Role: PI (with J. Jiang)
Dates 04/01/09 to 03/31/13
Effort: 2.4 calendar
Summary: The underlying hypothesis of this application is that laser-induced photoacoustic
tomography provides a new high resolution, functional neuroimaging modality for imaging
epilepsy.
Title: Noninvasive Functional and Cellular Imaging of Epilepsy
Agency: NIH 1R01NS069848-01
Dates: 02/15/2010 to 01/31/2014
Effort: 1.8 calendar
Role: MPI
Summary: The primary goal of this project is to develop a DOT system for accurate localization
of epileptic focus. We also propose to study the neuro-vascular and neuro-cellular coupling of
neuronal activity and hemodynamic/cellular response using concurrent EEG and DOT
noninvasively in an epilepsy animal model.
Title: Control of Neural Synchrony with Light-Activated Opsins Working Group
Agency: University of Florida Computational Biology Working Group Seed Grant RFA
Direct: $80,000
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Dates: 04/01/10 to 03/31/11
Role: MPI
Agency: Cyberonics, Inc
Seizure prediction and detection
Dates: 10/01/10 to 09/30/11
Role: PI
Amount: $100,000
Pending Research Grant Support
Title: Brain-susceptibility-matched electrodes and cannula for distortion-free MR
Agency: NIH/NINDS
Role: PI
Dates: 04/01/2011 to 03/31/2013
Title: Ultrasound to control epilepsy: Sonoluminescent activation of neuron ion channels
Agency: NIH/NINDS
Role: Co-PI
Dates: 04/01/2011 to 03/31/2013
Title: Predicting Epilepsy in Limbic Brain Networks Derived from Diffusion MR Imaging
NIH/NINDS
Role: PI
Dates: 04/01/2011 to 03/31/16
Effort: 1.8 calendar
Title: Enhanced MR Imaging of Epileptogenesis with Histological Validation
Agency: NINDS/NIH
Dates: 07/01/08 to 06/30/11
Role: PI
Effort: 1.8 calendar
Title: Do GABA-ergic Anesthetics Generate Excitotoxicity in Neonates and Infants during
General Anesthesia?
Agency: NINDS/NIH (Martynyuk)
Dates: 04/01/09 to 03/31/11
Effort: 0.6 calendar
Score 10th
percentile, funding pending
Summary: The goal of this project is to assess the excitotoxicity effects of GABA in young
rodent pups.
Title: Early Diagnosis of Autism Using High-Angular-Resolution Diffusion Magnetic Resonance
Imaging
Agency: USAMRMC
Role: PI
Paul Richard Carney
19
Dates: 11/01/08 to10/31/11
Effort: 1.8 calendar
Summary: The major goals of this project are to develop optimized MR HARDI acquisition
protocols, novel computationally efficient algorithms for MR HARDI denosing, to visualize the
displacement probability density field of white matter tracks in individuals with autism. We then
plan to use these methods to predict the onset of autism in young children.
Title: Collaborative Research in Computational Neuroscience: Chronobiology of Epilepsy
Agency: NSF CRCNS (Carney)
Dates: 01/01/09-12/31/13
Effort: 2.4 calendar
Summary: The goal of this research is to understand the influence of endogenous circadian
control on hippocampus postsynaptic activity in a rat model of limbic epilepsy.
Title: Spatial Measures of Connectivity for Early Seizure Prediction
Agency: Epilepsy Foundation of America
Dates: 01/10/09 to 12/31/09
Role: Postdoctoral Mentor to Post Doc Alex Cadotte, Ph.D.
Amount: $45,000
Summary: The primary aim of this study is to investigate measures of effective connectivity
during seizures in a rat model of temporal lobe epilepsy
Title: Enhanced MR Imaging of Epileptogenesis with Histological Validation
Agency: NIH R21 NS065359
Dates: 04/01/09-03/31/11
Role: PI
Effort: 1.2 calendar
Summary: This work focuses on the development of enhanced magnetic resonance for the study
of the structural changes that lead to the development of epilepsy. MR results are statistically
correlated with brain dynamic measures from multisite local field recordings and co registered
with quantitative histology.
Title: Develop and Validate a Transport Model of Adeno-Associated Viral Vector Convection
Enhanced Delivery for the Treatment of Epilepsy
Agency: UF Research Opportunity Fund
Dates: 01/01/09-12/31/09
Summary: This study tests the hypothesis that convection-enhanced delivery of adeno-associated
viral vector can be optimized by measuring and predicting the spatial and temporal distribution
of the vector transport in the brain.
Title: Cerebrospinal Fluid Flow Analysis for Intrathecal Drug Delivery
Agency: UF Research Opportunity Fund
Role: PI
01/01/09-12/31/09
Summary: The goal of this research is to develop a predictive model for intrathecal delivery.
Paul Richard Carney
20
Title: Convection-Enhanced Delivery of Valproate-loaded Nanoparticles for Early Treatment of
Epilepsy
Agency: NIH RO1 Trans-NIH Recovery Act Research Support
Role : MPI
Dates: 10/01/09-09/30/11
Effort: 1.8 calendar
Summary: In this study we propose to provide neuroprotection through local delivery of a
histone deacetylase inhibitor drug, valproic acid, and determine if there is disruption of disease
progression in an established model of rat epilepsy. High concentrations of the drug, greater than
can be achieved through systemic delivery, will be achieved at the injury site using a novel drug
release system, direct tissue infusions of drug-loaded nanoparticles.
Title: CRNCS: Evolution into Epilepsy
Agency: NSF/NIH NIBIB R01-EB004752-01
Dates: 12/01/09 – 11/30/14
Effort: 2.4 calendar
Role: PI
Amount: $1,836,574.00
Summary: The basic project goals were to use our computational algorithms and models to
evaluate potential hypothesis on the underlying functional and structural mechanisms of
epileptogenesis in a validated animal model of temporal lobe epilepsy.
Title: Magnetoelencephalography
Agency: NIH Recovery Act Limited Competition: High-End Instrumentation Grant Program
(S10)
Role: PI
Title: Vagus Nerve Stimulation in an Animal Model of Chronic Limbic Epilepsy
Agency: NIH R21
Dates: 07/01/10-06/30/12
Effort: 1.2 calendar
Role: MPI
Summary: The aims of this project are to first test the efficacy of standard clinical vagus nerve
stimulation in a chronic model of limbic epilepsy and second to employ well-established
quantitative EEG tools in order to indentify the changes in brain dynamics in treatment
responders. The proposed research will provide the basis for a more extensive study of how to
develop more clinically efficacious VNS programming strategies through a better understanding
of the underlying changes in brain dynamics and periodic VNS.
Previous Research Grant Support
Title: Dichloroacetate Kinetics, Metabolism and Toxicity
Agency: NIH/NIEHS RO1
Dates: 07/01/04 to 06/30/09
Effort: 0.6 calendar
Paul Richard Carney
21
Role: Co-I (Stacpoole, PW)
Summary: This multicenter study investigates the natural history of childhood mitochondrial
cytopathy. DCA is employed as experimental compounds in order to ameliorate the effects of
lactic acidosis.
Title: Postdoctoral Fellowship- Statistical Performance Analysis of Early Seizure Detection
Algorithms
Agency: Epilepsy Foundation of America
Dates: 01/01/08 to 12/31/08
Role: Postdoctoral Mentor for Sachin Talathi
Amount: $40,000
Summary: The goal is to develop and validate a mathematical algorithm for seizure detection in
a validated rat model of temporal lobe epilepsy.
Title: Bioengineering Research Partnership in Brain Dynamics
Agency: NIH R01 EB002089
Dates: 07/19/01 to 04/30/07
Effort: 4.8 calendar
Role: MPI
Summary: The goal of the Brain Dynamics Bioengineering Research Partnership was to
develop an on-line, real-time Automated Seizure Warning and Prevention System for use by
epileptic patients and their caregivers.
Title: On-Line Real-Time Seizure Prediction
2006-07
Role: Co-PI
NIH/NINDS (R01-NS050582-01A1)
Amount: $2,382,724
Title: Novel Anti-Epileptic Drug Discovery: Somatostatin Receptor Modulation for Treating
Epilepsy
2004-06
Research Opportunity Fund Competition, Division of Sponsored Research, University of Florida
Role: PI
Amount: $100,000
Title: An EEG Method for Real-Time Detection of Neonatal Seizures in the Neonatal Intensive
Care Unit
2003-06
Epilepsy Foundation of America Partnership for Pediatric Epilepsy Research Foundation
Role: PI
Amount: $75,000
Title: Outcome of Therapeutic Hypothermia in Pediatric Arrest
R21 HD 044981
Paul Richard Carney
22
2003 -06
NIH/NICHD
Role: Co-I
$290,000
Title: Pediatric Epilepsy Program
Agency: Children’s Miracle Network Grant # 98HS-001
Amount: $2,587
Role: PI
Dates: 1998-99
Title: Epilepsy Monitoring Program
Agency: Children’s Miracle Network Grant # 98HF-015
Role: PI
Amount: $48,000
Dates: 1998-99
Title: Dynamical On-Line Real-Time Seizure Warning and Treatment in an Epilepsy-Prone
Rodent Model
Agency: University of Florida Division of Sponsored Research Opportunity Fund
Amount: $50,000
Role: PI
Dates: 2001-02
Title: In Vivo Neurophysiologic Characterization of the Epilepsy-Prone Sphingosine 1
Phosphate Receptor H218 Knockout Mouse
Agency: Children’s Miracle Network Grant
Role: PI
Amount: $40,000
Dates: 2000-01
Title: Dynamical Studies in Generalized Childhood Epilepsy
Agency: Biomedical Engineering Program
Dates: 1999-00
Role: PI
Amount: $25,000
Title: The Relationship between Sleep-Related Breathing Disorders and Hearing in Children
Agency: University of Florida College Investment Fund
Amount: $8,612
Role: PI
Dates: 1998-01
Title: Epilepsy Surgery Program
Agency: Children’s Miracle Network Grant # 99S-035 Intramural Patient
Paul Richard Carney
23
Amount: $16,700
Dates: 1999-00
Title: Sleep Disorders Center
Agency: Children’s Miracle Network Grant # 99S-056
Amount: $7,500
Role: PI
Dates: 1999-2000
Title: Pediatric EEG/Sleep
Agency: Children’s Miracle Network Grant # 2000-044
Amount: $3,330
Role: PI
Dates: 2000-01
Title: Ketogenic Eggnog versus Ketogatornog Treatment for Seizures
Agency: Ross Foods, Inc.
Role: PI
Amount: $3,500
Dates: 1998-01
Title: Prevention of Dicloroacetate Toxicity
Agency: FD-R-002013-01
Role: Co-I
Amount: $880,000
Dates: 2001-04
Title: Subcortical Executive Function and Frontal Lobe Childhood Epilepsy
Agency: Epilepsy Foundation of America
Role: Mentor for Susan Bongiolatti Doctoral Student
Amount: $40,000
Dates: 2004-05
Title: On-Line Real-Time Seizure Prediction in Adult Patients with Epilepsy
Agency: Office of Technology Licensing, University of Florida Division of Sponsored Research
Amount: $26,872
Dates: 2004-05
Title: A Multicenter, Double-Blind, Placebo-Controlled, Randomized, Stratified, Parallel-Group
Trial of the use of Telecommunications in Evaluating Compliance in Teen Epilepsy
Agency: NIH
Dates: 1998-03
Title: Home-based telecommunication mediated counseling for rural teens with epilepsy: multi-
point group vs. single family approaches
Paul Richard Carney
24
Agency: NIH (NINDS)
Dates: 1998-03
Title: Preictal detection and seizure prevention in a transgenic mouse model of childhood
epilepsy
Agency: Children’s Miracle Network
Amount: $1,000
Dates: 2001-02
Title: Dichoroacetate Treatment of Congenital Acidosis
NIH, PA-94-036
$1,005,282
1998-00
Past Industry Research Support
Title: Rufinamide as adjunctive therapy in children and adults with inadequately controlled
partial seizures,
Novartis, Inc.,
1998-99
Title: In patient rufinamide as adjunctive therapy in children and adults with inadequately
controlled partial seizures
Novartis, Inc.
2000-01
Title: A multi-center, double-blind, randomized, placebo-controlled, parallel-group evaluation of
lamotrigine adjuntive therapy in subjects with primary generalized tonic-clonic seizures
Glaxo-Wellcome, Inc.
2001-02
Evaluation of the efficacy and tolerability of Levetiracetam add on treatment in refractory
pediatric patients with partial onset seizures
GlaxoSmithKline Grant # LAM40013
2002-03
Title: A Multicenter, Open label conversion of valproate monotherapy to lamotrigine
monotherapy in patients with epilepsy
Abbott Pharmaceuticals, Inc.
2002-03
Title: A multicenter, open label conversion of valproate monotherapy to lamotrigine
monotherapy in patients with epilepsy
GlaxoSmithKline Grant # LAM 40013
2002-04
Paul Richard Carney
25
Title: Evaluation of the efficacy and tolerability of levetiracetam add-on treatment in refractory
pediatric patients with partial onset seizures: A 28-week double-blind placebo-controlled
multicenter trial
UCB Pharma Inc.
2002-03
Title:A multi-center open label, pilot study of lamotrigine as adjunctive therapy and
monotherapy in patients with epilepsy and co morbid depressive symptoms
GlaxoSmithKline Grant # LAM40117
2002-03
BIBLIOGRAPHY
Completed Publications in Scientific Journals
Peer-Reviewed Papers
1. Carney PR and Silver J. Studies on cell migration and axon guidance in the developing
distal auditory system of the mouse. J Comp Neur. 1983; 225:359-369.
2. Poston MR, Fredieu J, Carney P, Silver J. The role of glia and neural crest cells in creating
axon pathways and boundaries in the vertebrate central and peripheral nervous systems. In:
The Making of the Nervous System. Oxford University Press, Parnavelas JG, Stern CD,
Stirling RV, Eds. 1986, 282-313.
3. Carney PR, Couve E. Cell polarity changes and migration during early development of the
avian peripheral auditory system. Anat Rec.1989; 215:156-164.
4. Okun MS, Jummani RR, Carney PR. Antiphospholipid- associated recurrent chorea and
ballism in a child with cerebral palsy. Pediatr Neurol. 2000; 23(1):62-3.
5. Tran TX, Day JA, Eskin TA, Carney PR, Maria BL. Rasmussen’s syndrome: Etiology,
clinical features, and treatment options. CNS Drugs 2000; 14:343-354.
6. Kohrman MH, Carney PR. Sleep-related disorders in neurologic disease during childhood.
Pediatr Neurol. 2000; 23 (2):107-13.
7. Kramer MJ, LaRussa P, Tsai W, Carney P, Leber S, Gahagan S, Steinberg S, Blackwood A.
Disseminated vaccine strain varicella as the acquired immunodeficiency syndrome-defining
illness in a previously undiagnosed child. Pediatrics 2001; 108(2): e39-46.
8. Carney PR, Paige P. Neurologic Disorders. In: Handbook of Neonatal Intensive Care. Eds.
Merenstein, GB, Gardner SL. Pub. Mosby, 5th
ed. 2001; 644-678.
9. Carney PR. Rasmussen’s syndrome: Intractable epilepsy and progressive neurological
deterioration from a unilateral central nervous system disease. CNS Spectrums
2001;6(5):398-416.
10. MacLennan AJ, Carney PR, Zhu WJ, Chaves AH, Garcia J, Grimes JR, Anderson KJ, Roper
SN, Lee N. An essential role for the H218/AGR16/Edg-5/LP(B2) sphingosine 1-phosphate
receptor in neuronal excitability. Eur J Neurosci. 2001; 14(2): 203-9.
11. Carney PR, Korhman, MH. Relation between epilepsy and sleep during infancy and
childhood. In: Sleep and Epilepsy: The Clinical Spectrum. Eds. Malow BM, Bazil C,
Sammaritano M. Pub. Elsevier Science 2002; 359-372.
Paul Richard Carney
26
12. Glueckauf RL, Fritz SP, Ecklund-Johnson EP, Liss HJ, Dages P, Carney P.
Videoconferencing-based family counseling for rural teenagers with epilepsy: Phase 1
findings. Rehab Psychol. 2002; 47(1):49-72.
13. Iasemidis LD, Pardalos PM, Shiau DS, Chaowolitwongse W, Narayanan K, Kumar S,
Carney PR, Sackellares JC, Prediction of human epileptic seizures based on optimization
and phase changes of brain electrical activity. Optimization Methods and Software 2003;
18(1):81-104.
14. Yatsenko V, Carney P, Pardalos P, Sackellares JC, Shiau DS. Control of chaotic systems: a
practical application to epilepsy, Proc. of Second International Conference on Control
Problems, Moscow, Institute of Control Problems. 2003; 205-218.
15. Yatsenko V, Sackellares C, Pardalos P, Carney P. Geometric models, fiber bundles and
biomedical applications. Fifth International Conference: Symmetry in Nonlinear
Mathematical Physics, Institute of Mathematics. Kiev, 2003; 195-217.
16. Iasemidis LD, Shiau DS, Chaovalitwongse W, Sackellares JC, Pardalos PM, Principe JC,
Carney PR, Prasad A, Veeramani B, Tsakalis K. Adaptive epileptic seizure prediction
system. IEEE Trans Biomed Eng. 2003 May; 50(5):616-27.
17. Becker DA, Fennell, EB, Carney PR. Sleep disturbance in children with epilepsy. Epilepsy
Behav. 2003; 4(6):651-8.
18. Stickler DE, Carney PR, Valenstein ER. Juvenile-onset Leigh syndrome with an acute
polyneuropathy at presentation. Child Neurol. 2003; 18(8):574-6.
19. Becker DA, Fennell EB, Carney PR. Daytime behavior and sleep disturbance in childhood
epilepsy. Epilepsy Behav 2004; 5: 708-15.
20. Sackellares JC, Iasemidis LD, Shiau LD, Pardalos PM, Carney PR. Spatiotemporal
transitions in temporal lobe epilepsy. Quantitative Neuroscience: Models, Algorithms,
Diagnostics, and Therapeutic Applications. Kluver Academic Publishers 2004; 223-38.
21. Shiau DS, Chaovalitwongse W, Iasemidis LD, Pardalos PM, Carney PR, Sackellares JC.
Nonlinear dynamical and statistical approaches to investigate dynamical transitions before
epileptic seizures. Quantitative Neuroscience: Models, Algorithms, Diagnostics, and
Therapeutic Applications. Kluver Academic Publishers 2004; 239-50.
22. Yang MCK, Shiau DS, Sackellares JC, Carney PR. Testing whether a prediction scheme is
better than guess, In: Pardalos PM, Sackellares JC, Carney PR, and Iasemidis LD (eds.)
Quantitative Neuroscience, Kluver Academic Publishers 2004; 251-259.
23. Carney PR, Shiau DS,
Pardalos PM, Iasemidis LD, Chaovalitwongse W, Sackellares JC.
Nonlinear neurodynamical features in an animal model of generalized epilepsy. Quantitative
Neuroscience: Models, Algorithms, Diagnostics,and Therapeutic Applications. Kluver
Academic Publishers, 2004, 37-52.
24. Pardalos PM, Chaovalitwongse W, Iasemidis LD, Sackellares JC, Shiau DS, Carney PR,
Prokopyev OA, Yatsenko VA. Seizure warning algorithm based on optimization and
nonlinear dynamics. Math. Program Ser B, 35-50: 2004.
25. Pardalos PM, Boginski VL, Prokopyev OA, Suharitdamrong W, Carney PR,
Chaovalitwongse W, Vazacopoulos A. Optimization Techniques in Medicine. In: Eds. Audet
C, Hansen P, Savard G. Essays and Surveys in Global Optimization. Springer, 2005; 151-
173.
Paul Richard Carney
27
26. Sanchez JC, Principe JC, Carney PR. Is neuron discrimination preprocessing necessary for
linear and nonlinear brain machine interface models? 11th International Conference on
Human-Computer Interaction, 2005; 1100-1115.
27. Iasemidis LD, Shiau DS, Pardalos PM, Chaovalitwongse W, Narayanan K, Prasad A,
Tsakalis K, Carney PR, Sackellares JC. Long-term prospective on-line real-time seizure
prediction. Clin Neurophysiol. 2005 Mar; 116(3):532-44. Epub 2005 Jan 6.
28. Chaovalitwongse W, Iasemidis LD, Pardalos PM, Shiau DS, Sackellares JC, Carney PR.
Performance of a seizure warning algorithm based on the dynamics of intracranial EEG.
Epilepsy Res. 2005 May; 64(3):93-113. William Pierskalla Best Paper Award, Institute for
Operations Research and the Management Sciences.
29. Dharnidharka VR and Carney PR. Isolated idiopathic hypomagnesemia presenting as
aphasia and seizures. Pediatr Neurol. 2005 Jul; 33(1):61-5.
30. Shiau DS, Nair SP, Iasemidis LD, Norman
W, Principe JC, Pardalos PM, Suharitdamrong
W,
Cho J, Sackellares JC, Carney PR. Seizure warning and dynamic response to electrical
stimulation in a rodent model of chronic limbic epilepsy. IEEE Engineering in Medicine and
Biology. 2005; 95-100.
31. Iasemidis LD, Shiau DS, Pardalos PM, Chaovalitwongse W, Narayanan K, Prasad A,
Tsakalis K, Sackellares JC, Carney PR. Long-term prospective on-line real-time seizure
prediction. Clinical Neurophysiol. 2005; 116 (3): 532-544.
32. Chaovalitwongse W, Pardalos PM, Iasemidis LD, Carney PR, Shiau DS, Suharitdamrong
W, Sackellares JC. A robust method for studying the dynamics of the intracranial EEG:
Application to epilepsy. Epilepsy Res 2005; 64: 93-113.
33. Shiau DS, Nair SP, Iasemidis LD, Carney PR, Norman WM, Principe JC, Pardalos PM,
Suharitdamrong W, Cho J, Sackellares JC. Seizure warning and dynamic response to
electrical stimulation in a rodent model of chronic limbic epilepsy. Proceedings of 3rd
European Medical and Biological Conference, Prague, Czech Republic: Vol. 11, 2005.
34. Pardalos PM, Sackellares JC, Carney PR, Iasemidis LD. Quantitative Neuroscience:
Models, Algorithms, Diagnostics, and Therapeutic Applications. Kluver Academic
Publishers, Norwell, MA 2004.
35. Nair S, Sackellares JC, Shiau DS, Norman W, Dance L, Pardalos P, Principe JP, Carney
PR. Effects of acute hippocampal stimulation on EEG dynamics. IEEE Med Biol. 2006;1:
4382-6.
36. Mishra M, Jones
B, Simonotto
JD, Furman
MD, Norman
W, Liu
Z, DeMarse
TB, Carney
PR, Ditto WL. Pre-ictal correlation and entropy analysis of microwire data from an animal
model of limbic epilepsy. IEEE Eng Med Biol. 2006;1: 1605-7.
37. Chaovalitwongse WA, Iasemidis LD, Pardalos PM, Carney PR, Shiau DS, Sackellares JC.
Reply to comments on Performance of a seizure warning algorithm based on the dynamics of
intracranial EEG by Mormann, F., Elger, C.E., and Lehnertz, K, Epilepsy Res. 2006
Oct;71(2-3):241-2.
38. Simonotto JD, Myers
SM, Furman
MD, Norman
WM, Liu
Z, DeMarse TB, Ditto WL,
Carney PR. Coherence analyses over the latent period of epileptogenesis reveal that high-
frequency communication is increased across hemispheres in an animal model of limbic
epilepsy. IEEE Eng Med Biol. 2006; 1:1154-6.
Paul Richard Carney
28
39. Nelson R, Myers
S, Simonotto
J, Furman
M, Spano
M, Norman
W, Liu
Z, DeMarse T,
Ditto W, Carney PR. Detection of high frequency oscillations with teager energy in an
animal model of limbic epilepsy. IEEE Eng Med Biol Soc. 2006;1: 2578-80.
40. Sanchez JC, Carney PR, Principe JC. Analysis of amplitude modulated control features for
ecog neuroprosthestics. IEEE Eng Med Biol. 2006;1: 5468-71.
41. Qizhi Z, Liu Z, Carney PR, Jiang H. Imaging epilepsy using finite element-based
photoacoustic tomography: initial in vivo results. Biomedical Optics Tech Digest ME18;
2006
42. Geyer JD, Carney PR, Gilliam F. Focal epileptiform spikes in conjunction with k-
complexes. J Clin Neurophysiol. 2006 Oct; 23(5):437-440.
43. Sanchez JC, Mareci T, Norman W, Principe J, Ditto W, and Carney PR. Evolving into
epilepsy: Multiscale electrophysiological analysis and imaging in an animal model. Exp
Neurol. 2006 Mar; 198(1): 31-47.
44. Nair SP, Shiau DS, Iasemidis LD, Norman WM, Pardalos PM, Sackellares CS, Carney PR.
Seizure predictability in an experimental model of epilepsy. Proc Quant Neurosci Conf.
2006; 213-220.
45. Stickler DE, Valenstein E, Neiberger RE, Perkins LA, Carney PR, Shuster JJ, Theriaque
DW, Stacpoole PW. Peripheral neuropathy in genetic mitochondrial diseases. Pediatr
Neurol. 2006 Feb; 34(2):127-31.
46. Miller J, Carney P. Central hypothyroidism with oxcarbazepine therapy. Pediatr Neurol.
2006 Mar; 34(3): 242-4.
47. Stacpoole PW, Kerr DS, Barnes C, Bunch ST, Carney PR, Fennell E, Felitsyn NM,
Gilmore R, Greer M, Henderson G, Hutson AD, Neiberger R, O’Brien R, Perkins LA,
Quisling R, Shroads AL, Shuster JJ, Silverstein JH, Theriaque DW, Valenstein E. A
controlled clinical trial of dichloroacetate for treatment of congenital lactic acidosis in
children. Pediatrics 2006 May; 117(5):1519-1531.
48. Sanchez JC, Alba N, Nishida T, Batich C, Carney PR. Structural modifications in chronic
microwire electrodes for cortical neuroprosthetics. IEEE TNSRE 2006;14(2): 217-221.
49. Chaovalitwongse WA, Iasemidis LD, Pardalos PM, Carney PR, Shiau DS, Sackellares JC.
Reply to comments on Performance of a seizure warning algorithm based on the dynamics of
intracranial EEG by Mormann, F., Elger, C.E., and Lehnertz, K. Epilepsy Res. 2006 Nov;
72(1):85-7.
50. Chaovalitwongse W, Pardalos PM, Iasemidis LD, Suharitdamrong DS, Dance LK, Prokopyev
OA, Boginski VL, Carney PR, Sackellares JC. Data mining in EEG: applications to epileptic
brain disorders. In: Data Mining in Biomedicine. Series: Springer Optimization and its
Applications, Pardalos, Panos M. Boginski, Vladimir L; Vazacopoulos, Alkis (Eds.), 7:459:
2007.
51. Shaiu DS, Iasemidis LD, Yang MCK, Pardalos PM, Carney PR, Dance LD,
Chaovalitwongse W, Sackellares JC. Automated seizure prediction algorithm and its
statistical assessment: a report from ten patients. In: Data Mining in Biomedicine. Series:
Springer Optimization and its Applications, Pardalos, Panos M. Boginski, Vladimir L;
Vazacopoulos, Alkis (Eds.), 7:517:2007.
Paul Richard Carney
29
52. Nair SP, Shiau DS, Iasemidis LD, Norman WM, Pardalos PM, Sackellares JC, Carney PR.
Seizure predictability in an experimental model of epilepsy. In: Data Mining in Biomedicine.
Series: Springer Optimization and its Applications, Pardalos, Panos M. Boginski, Vladimir L;
Vazacopoulos, Alkis (Eds.), 7:535:2007.
53. Prokopyev OA, Boginski VL, Chaovalitsongse W, Pardalos PM, Sackellares JC, Carney PR.
Network-based techniques in EEG data analysis and epileptic modeling. In: Data Mining in
Biomedicine. Series: Springer Optimization and its Applications, Pardalos, Panos M.
Boginski, Vladimir L; Vazacopoulos, Alkis (Eds.), 7:559:2007.
54. Hwang Dong-UK, Talathi S, Carney PR, Ditto W, Myers S, Norman W, Simonotto J. High
frequency oscillations in the limbic rat model of temporal lobe epilepsy. Computational
Neuroscience, 2007.
55. Martynyuk AE, Ucar DA,
Yang DD, Norman WM, Carney PR, Dennis DM, Laipis PJ.
Epilepsy in phenylketonuria: A complex dependence on serum phenylalanine levels.
Epilepsia. 2007 Jun; 48(6):1143-50.
56. Jian B, Vemuri BC, Ozarslan E, Carney P, Mareci T. A novel tensor distribution model for
the diffusion weighted MR signal. Neuroimage. 2007 Aug 1;37 (1):164-76.
57. Ramirez-Manzanares A, Rivera M, Vemuri BC, Carney P, Mareci T. Diffusion basis
functions decomposition for estimating white matter intra-voxel fiber geometry. IEEE
Transactions on Medical Imaging, 2007; 26:1091-1102.
58. Talathi SS, Hwang DU, Ditto W, Carney PR. Early seizure detection in an animal model of
temporal lobe epilepsy, Data Mining, Systems Analysis and Optimization in Biomedicine,
AIP Conf Proc, 2007; 953:292-307.
59. Sanchez JC, Gunduz A, Carney PR, Principe JC. Extraction and localization of mesoscopic
motor control signals for human ECoG neuroprosthetics. J Neurosci Methods. 2008;167
(1):63-81.
60. Wang Q, Liang X, Liu Z, Zhang Q, Carney PR, Jiang
H. Visualizing localized dynamic
changes during epileptic seizure onset in vivo with diffuse optical tomography. Med Phys.
2008;1: 216-224.
61. Zhang Q, Liu Z, Carney PR, Yuan Z, Chen X. Roper SN, Jiang H. Noninvasive imaging of
epileptic seizures in vivo using photoacoustic tomography. Phys. Med. Biol. 2008 53:1921-
1931.
62. Talathi SS, Hwang DU, Ditto WL, Spano M, Myers SM, Winters, J, Simonotto J, Carney
PR. Non-parametric early seizure detection in an animal model of temporal lobe epilepsy. J
Neural Eng. 2008 Mar; 5 (1):85-98.
63. Carney PR, Cadotte A, DeMarse TB, Vemuri B, Mareci T. Ditto W. Effective and
anatomical connectivity in a rat model of spontaneous limbic seizures. In: Seizure Prediction
in Epilepsy: From Basic Mechanisms to Clinical Application. Wiley Vch Verlag GmbH &
Co. KGaAA, Schelter B, Timmer J, Schultze-Bonhage A, Eds, 45-59, 2008.
64. Stacpoole PW, Gilbert LR, Neiberger RE, Carney PR, Valenstein E, Theriaque DW,
ShusterJJ. Evaluation of long-term treatment of children with congenital lactic acidosis with
dichloroacetate. Pediatrics. 2008 May;121(5):e1223-8.
65. Geyer JD, Carney PR, Dillard SC, Davis L, Ward LC. Antidepressant medications,
neuroleptics and prominent eye movements during NREM Sleep. J Clin Neurophysiol. 2009
Feb; 26(1):39-44.
Paul Richard Carney
30
66. Nair SP, Shiau DS, Principe JC, Iasemidis LD, Pardalos PM, Norman WM, Kelly KM,
Sackellares JC, Carney PR. An investigation of EEG dynamics in an animal model of
temporal lobe epilepsy using the maximum Lyapunov exponent. Exp Neurol. 2009 Mar;
216(1):115-21.
67. Talathi SS, Hwang DU, Ditto WL, Mareci T, Sepulveda H, Carney PR. Circadian control of
neural excitability in an animal model of temporal lobe epilepsy. Neurosci Lett. 2009 May
15; 455(2):145-9.
68. Komalapriya C, Romano MC, Thiel M, Schwarz U, Kurths J, Simonotto J, Furman M, Ditto
WL, Carney PR. Predictability of spontaneous limbic seizures using recurrence measures.
Int. J. Bifurcation and Chaos, 19 (2) 605-617, 2009.
69. Cadotte A, Mareci T, DeMarse T, Prarekh M, Rajagovindan R, Ditto W, Talathi S, Hwang
DU, Carney PR. Temporal lobe epilepsy: anatomical and effective connectivity. IEEE
Trans Neural Syst Rehabil Eng. 2009 Jun; 17 (3):214-23.
70. Gunduz A, Sanchez JC, Carney PR, Principe JC. Mapping broadband electrocorticographic
motor control features to two-dimensional hand trajectories in humans motor control features.
Neural Netw. 2009 Nov;22(9):1257-70
71. Talathi SS, Hwang DU, Miliotis A, Carney PR, Ditto WL. Predicting synchrony in
heterogeneous pulse coupled oscillators. Phys Rev E Stat Nonlin Soft Matter Phys. 2009 Aug;
80(2 Pt 1):021908.
72. Saxonhouse M, Tarquinio D, Carney P, Bennett J, Smith A, Hunger S, Geyer J. Low
molecular weight heparin use in a case of noncardiogenic multifocal perinatal
thromboembolic stroke. Adv Hematol. 2009:153643.
73. Kumar R, Vemuri BC, Wang F, Syeda-Mahmood T, Carney PR, Mareci TH. Multi-fiber
reconstruction from DW-MRI using a continuous mixture of hyperspherical von Mises-
Fisher distributions. Inf Process Med Imaging. 2009; 21:139-50.
74. Talathi, SS, Hwang D, Carney, PR, Ditto W. Synchrony with shunting inhibition in a
feedforward inhibitory network. J Comput Neurosci. 2010 Apr; 28(2):305-21.
75. Astary GW, Kantorovich S, Carney
PR, and Mareci
TH, Malisa Sarntinoranont
M. Regional
convection enhanced delivery of gadolinium labeled albumin into the rat hippocampus in
vivo. J Neurosci Methods. 2010 Mar 15;187 (1):129-37.
76. Cadotte AJ, DeMarse TB, Mareci TH, Parekh M, Talathi SS, Hwang DU, Ditto WL, Ding M,
Carney PR. Granger causality relationships between local field potentials in an animal
model of temporal lobe epilepsy. J Neurosci Methods. 2010 May 30;189(1):121-9.
77. Fisher N, Talathi SS, Carney PR, Ditto WL. Effects on homeostatic spike rate. Biol Cybern.
2010 May; 102(5):427-40.
78. Nandan M, Talathi SS, Myers S, Ditto WL, Khargonekar PP, Carney PR. Support vector
machine algorithms for seizure detection in an animal model of chronic epilepsy. J Neural
Eng. 2010 Jun;7(3):036001.
79. Parekh MB, Carney PR, Sepulveda H, Norman W, King M, Mareci TH. Early MR Diffusion
and Relaxation Changes in the Parahippocampal Gyrus Precede the Onset of Spontaneous
Seizures in an Animal Model of Chronic Limbic Epilepsy. Exp Neurol. 2010 Apr 12; 224
(1):258-270.
80. Talathi SS, Carney PR, Khargonekar PP, Control of neural synchrony using
channelrhodopsin-2: A computational study, J Comput Neurosci. 2010 Dec 21.
Paul Richard Carney
31
Under Review
1. Tarquinio D, Smith A, Bennett J, Carney PR, Hunger SP, and Saxonhouse MA. A severe
case of multi-focal cerebral infarction in a full-term neonate: is anticoagulation necessary?
Pediatric Neurology.
2. Gunduz A, Sanchez JC, Carney PR, Principe JC. Deciphering two-dimensional hand
trajectories from broadband ecog in humans. IEEE TNSRE.
3. Gunduz A, Sanchez JC, Carney PR, Principe JC. Analysis of movement-related features in
broadband human electrocorticography for deciphering two-dimensional hand trajectories. J
Neurosci Methods.
4. Geyer JD, Lichstein KL, Ruiter ME, Carney PR, Dillard SC. Paradoxical insomnia and
cognitive intervention. J Clinical Sleep Medicine.
5. Geyer JD, Lichstein KL, Ruiter ME, Ward LC, Carney PR, Dillard SC. Sleep education for
paradoxical insomnia. J Behavioral Sleep Medicine.
6. Goodmon K, Gulati S, Jones
LL, Concepcion
L, Liu Z MD, Andrade E, Carney PR, Borum
PR. AED Medication Score: A Tool to Assess the Efficacy of Ketogenic Therapy. Pediatric
Neuology.
7. Carney PR, Talathi SS, Hwang DU, Ditto W. Circadian Regulation of Neural Excitability
in Temporal Lobe Epilepsy. Chapter 19, Ed: Osorio I. International Seizure Prediction
Conference Proceedings, 2010.
In preparation
1. J. H. Kim, G. Astary, S. Kantorovich, T. H. Mareci, P. Carney, M. Sarntinoranont.
Computational Model and In Vivo MR Experiments for Convection Enhanced Delivery in the
Rat Ventral Hippocampus.
2. J. H. Kim, G. Astary, T. L. Nobrega, T. H. Mareci, P. Carney, M. Sarntinoranont. Dynamic
Contrast-Enhanced MRI of Gd-albumin Delivery to the Rat Hippocampus In Vivo by
Convection-Enhanced Delivery.
Textbooks
1. James D. Geyer, Paul R. Carney, Troy T. Payne, Michael Aldrich. Atlas of Digital
Polysomnography. 1st ed. Lippincott-Williams & Wilkins, Inc., Philadelphia, 2000.
2. Paul R. Carney, James D. Geyer, Richard Berry, eds. Clinical Sleep Disorders, 1st ed.
Lippincott Williams & Wilkins, Inc., Philadelphia, 2005.
3. James D. Geyer, Janice M. Keating, Daniel C. Potts, Paul R. Carney. Neurology for the
Boards, 3rd
ed. Lippincott-Williams & Wilkins, Inc., Philadelphia, 2006.
4. James D. Geyer, Daniel C. Potts, Edward E. Marsh, Paul R. Carney. Neurology for Wards
and Mini-Boards: The Complete Medical Student Guide. 1st ed. Lippincott-Williams &
Wilkins, Inc., Philadelphia 2009.
5. Paul R. Carney and James D. Geyer JD. Pediatric Practice: Neurology, McGraw Hill
Professional Pubs, 1st edition. 2009.
6. L. John Greenfield, James D. Geyer, Paul R. Carney. Reading EEGs: A Practical
Approach. 1st ed. Lippincott-Williams & Wilkins, Inc., Philadelphia 2009.
7. James D. Geyer, Paul R. Carney, Troy T. Payne. Atlas of Digital Polysomnography. 2nd
ed.
Lippincott-Williams & Wilkins, Inc., Philadelphia, 2009.
Paul Richard Carney
32
Textbooks under preparation
1. Paul R. Carney, James D. Geyer, Richard Berry, eds. Clinical Sleep Disorders, 2nd
ed.
Lippincott-Williams & Wilkins, Inc., Philadelphia, 2011.
2. Paul R. Carney and James D. Geyer. Clinical Neurophysiology: Methods and Clinical
Applications. CRC Press. 2011.
Monographs and Book Chapters
1. Becker DA, Bongiolatti SR, Carney PR. (2005). Sleep questionnaires. In: Carney PR,
Geyer JD, Berry R, eds. Clinical Sleep Disorders, 1st ed. Philadelphia: Lippincott Williams
& Wilkins 2005; 479-481.
2. Carney PR, Becker DA, Bongiolatti S. (2005) Ontogeny of Sleep. In: Carney PR, Geyer
JD, Berry R, eds. Clinical Sleep Disorders, 1st ed. Philadelphia: Lippincott Williams &
Wilkins 2005; 95-98.
3. Becker D, Carney PR. Pediatric and adolescent presentations. In: Carney PR, Geyer JD,
Berry R, eds. Clinical Sleep Disorders, 1st ed. Philadelphia: Lippincott Williams & Wilkins
2005; 136-146.
4. Berry R, Geyer JD, Carney PR. Introduction to sleep medicine. In: Carney PR, Geyer JD,
Berry R, eds. Clinical Sleep Disorders, 1st ed. Philadelphia: Lippincott Williams & Wilkins:
2005; 3-28.
5. Becker D, Bongiolatti S, Carney PR. Sleep questionnaires. In: Carney PR, Geyer JD, Berry
R, eds. Clinical Sleep Disorders, 1st ed. Philadelphia: Lippincott Williams & Wilkins 2005;
479-481.
6. Ringdahl D, Snively C, Carney PR. Pharmacological treatments. In: Carney PR, Geyer JD,
Berry R, eds. Clinical Sleep Disorders, 1st ed. Philadelphia: Lippincott Williams & Wilkins
2005; 484-487.
Geyer JD, Carney PR, Dillard SC, Tsikhlakis JC. Sleep and Vascular Disorders. In:
Stroke: A Practical Approach. Edited by James D. Geyer and Camilo R. Gomez, Wolters
Kluwer, Lippincott Williams & Wilkins, Phil. 2009:100-106.
7. Carney PR, Geyer JD, Saxonhouse MA, Gomez CR, Malaty I. Pediatric Stroke. In:
Stroke: A Practical Approach. Edited by James D. Geyer and Camilo R. Gomez, Wolters
Kluwer, Lippincott Williams & Wilkins, Phil. 2009:130-140.
8. Geyer JD, Carney PR, Lichstein K, Dillard SC, Henderson MM. Sleep and Acute Stroke.In:
Stroke: A Practical Approach. Edited by James D. Geyer and Camilo R. Gomez, Wolters
Kluwer, Lippincott Williams & Wilkins, Phil. 2009:301-307.
9. Fisher N, Talathi S, Cadotte A,
Meyers, S, Carney PR
Epilepsy Detection and
Monitoring, In: Quantitative EEG Analysis Methods and the Application. Eds: Shanbao
Tong and Nitish V. Thakor, Artech House, Inc., of Norwood, MA, USA, pp 141-167, 2009.
10. Carney PR, Fisher N,
Ditto, WL. Geyer JD. Quantitative Sleep Monitoring. In:
Quantitative EEG Analysis Methods and the Application. Editors: Shanbao Tong and Nitish
V. Thakor, Artech House, Inc., of Norwood, MA, USA, pages 257-288, 2009.
11. Carney PR. Geyer JD, Tinuper P. Bisulli F, Provini F. Treating Epilepsy in the Presenceof
Sleep Disorders. Chapter 34, In: Medical and Surgical Treatment of Pediatric Epilepsy. Eds:
Helen Cross, Michael Duchowny, Tracy Glauser, Edouard Hirsch, Alexis Arzimanoglou.
McGraw-Hill Pubs, 2009.
Paul Richard Carney
33
12. Carney PR. Alterations of Consciousness New Patient. In: Child Neurology Telephone
Encounter Guides. Eds. Sprague-McRae, J, Rosenblum R, Morrison L. Association of Child
Neurology Nurses, 1st Ed., 2009.
13. Philip Barish, Svetlana Kantorovich, Paul R. Carney, William Ogle. Decoding Neural
Circuitry with Optogenetics: Applications for Epilepsy. From the Hallowed Halls of Herpes
virology – A Tribute to Bernard Roizman. Eds.: John A. Blaho and Joel D. Baines, Editors
World Scientific Publishing / Imperial College Press, 2010.
14. Carney PR, Talathi SS, Geyer JD. Pediatric Sleep Issues. Chapter 21, Sleep Medicine
Updates, Ed. Octavian Ioachimescu, 1st edition, Bentham Publishing, E-Book, In Press.
Peer- Reviewed Conference Proceedings and Meeting Abstracts
1. Carney PR, Silver J. A mechanism for the guidance of peripheral spiral ganglion cell axons
in the developing mouse auditory system. Soc. Neurosci. XVI, 1980; 6:487.
2. Carney PR, Silver J, Manubens L. Cell migration and axon guidance in the developing rat
auditory system. 3 rd Reg. Chile Biol. Soc. 1983; 4:10.
3. Carney PR, Couve E. Cell polarity changes and migration during early development of the
avian peripheral auditory system Fourth International Congress of Cell Biology (Montreal).
1988; 7.2.28.
4. Larson W, Carney P, Aldrich M. Atypical presentation of Leigh disease in a teenage
woman. Mitochondrial Diseases Symposium. Indianapolis, Ind., 1995.
5. Payne T, Kothary S, Varma N, Nasreddine W, Carney P, Shu V, Beydoun A. Serum
sodium and thyroid function after replacement of carbamazepine with oxcarbazepine.
Epilepsia 1997; 3.023.
6. Carney P, Nasreddine W, Drury I, Varma N, Payne T, Shu V, Beydoun A. The
relationship between thrombocytopenia and valproate dose. Epilepsia 1997; 3.054.
7. Carney PR, Blaivas M, Drury I. Histopathological findings in a familial form of medically
refractory temporal lobe epilepsy. Epilepsia 1998.
8. Herrmann DN, Carney PR, Wald JJ. Juvenile myasthenia gravis: treatment with immune
globulin and thymectomy. Pediatr Neurol. 1998; 18:63-66.
9. Tran TX, Palmer SC, Ni OK, Muir AB, Carney PR. Epilepsia partialis continua as a
presenting manifestation of diabetic ketoacidosis. Ann Neurol. 1999; 46: 96.
10. Muir A, Carney PR. Epilepsia partialis in a ketoacidotic child. Ann Neurol. 1999;
46:96.Tran TX, Palmer SC, Ni O, Iasemidis LD, Pardalos PM, Srivastava A, Won J, Shiau
DS,Lee N, MacLennan AJ, Sackellares JC, Carney PR. Predictability of seizures in an
epilepsy-prone transgenic mouse model, Epilepsia 2001; 42 (7): 225.
11. Saxonhouse MA, Bhatti MT, Driebe WT, Freeman BE, Maria BL, Carney PR. Primary
antiphospholipid syndrome presenting with a branch retinal artery occlusion in a 15-year-old
boy. J Child Neurol. 2002; 17(5):392-4.
12. Sackellares JC, Shiau DS, Iasemidis L, Pardalos P, Chaovalitwongse W, Carney PR. Can
knowledge of cortical cite dynamics in a preceding seizure be used to improve prediction of
the next seizure? Annals Neurol. 2002; 52 (3S), S65-S66.
13. Carney PR, Maze MF, Shiau DS, Srivastiva A, Iasemidis LD, Pardalos PM, Sackellares,
JC. State-specific nonlinear neurodynamic features in an animal model of generalized
epilepsy. Epilepsia 43 Suppl. 7 :270 (Abst. 3.063 ) , 2002.
14. Shiau DS, Sackellares JC, Iasemidis LD, Maze MF, Carney PR. Nonlinear Approximate
Paul Richard Carney
34
Entropy Analysis of Brain Electrical Activity in a Generalized Epilepsy Animal Model.
Epilepsia 2002; 443 (7): 273.
15. Sackellares JC, Iasemidis LD, Shiau DS, Chaovalitwongse W, Pardalos P, Carney PR.
Dynamical Dependence of Seizure Prediction on Preceding Seizures. Epilepsia 43 Suppl.
7 :50 (Abst.1.136), 2002
16. Iasemidis LD, Shiau, DS, Chaovalitwongse W, Pardalos PM, Carney PR, Sackellares
JC. Adaptive Seizure Prediction System. Epilepsia 43 Suppl. 7:264 (Abst. 3.048 ), 2002.
17. Chaovalitwongse W, Iasemidis LD, Prasad A, Shiau, DS, Pardalos PM, Carney PR,
Sackellares JC. Seizure Prediction by Dynamical Phase Information from the EEG.
Epilepsia 43 Suppl. 7 :45 (Abst.1.121), 2002.
18. Snively C, McClernan CS, Maze MF, Carney PR. Efficacy and tolerability of the
ketogenic diet in the very young. Epilepsia 43 Suppl. 7:225 (Abst. 2.281), 2002.
19. Sackellares JC, Shiau DS, Iasemidis LD, Pardalos PM, Chaovalitwongse W, Carney
PR,Can knowledge of cortical site dynamics in a preceding seizure be used to improve
prediction of the next seizure? Ann Neurol. 2002; 52, (3S), S65-S66.
20. Chaovalitwongse W, Iasemidis LD, Prasad A, Shiau DS, Pardalos, PM, Carney PR,
Sackellares JC. Seizure prediction by dynamic phase information from the EEG.
Epilepsia 2002; 443(7):45.
21. Sackellares JC, Iasemidis LD, Shiau D-S, Chaovalitwongse W, Pardalos PM, Carney
PR. Dynamic dependence of seizure prediction on preceding seizures. Epilepsia 43
Suppl. 7:50 (Abst. 1.136) , 2002.
22. Iasemidis LD, Shiau D-S, Chaovalitwongse W, Pardalos PM, Carney PR, Sackellares
JC. Adaptive seizure-prediction system. Epilepsia 2002, 443(7): 264.
23. Carney PR, Maze MF, Shiau DS, Srivastiva A, Iasemidis LD, Pardalos PM, Sackellares,
JC. State-specific nonlinear neurodynamic features in an animal model of generalized
epilepsy. Epilepsia 2002; 443(7):270.
24. Shiau DS, Sackellares JC, Iasemidis LD, Maze MF, Carney PR. Nonlinear approximate
entropy analysis of brain electrical activity in a generalized epilepsy animal model.
Epilepsia 2002; 443(7):273.
25. Shiau DS, Iasemidis LD, Sackellares JC, Pardalos PM, Carney PR, Chaovalitwongse W.
Nonlinear Dynamics and Global Optimization Approaches to Investigate Dynamical
Transitions Before and After Epileptic Seizures. Quantitative Neurosciences Conference
at University of Florida, February 5-7, 2003.
26. Sackellares JC, Iasemidis LD, Shiau DS, Carney PR, Pardalos PM, Chaowalitwongse
W, Preictal Transition in Temporal Lobe Epilepsy. Quantitative Neurosciences
Conference at University of Florida, February 5-7, 2003.
27. Carney PR, Iasemidis LD, Sackellares JC, Srivastava A, Shiau DS, Maze MF, Zhang L,
MacLennan AJ, Pardalos PM. Seizure Prediction by Nonlinear Times Series Analyses of
Brain Electrical Activity in the H218 Animal Model. Quantitative Neurosciences
Conference at University of Florida, February 5-7, 2003.
28. Iasemidis LD, Sackellares JC, Pardalos PM, Shiau DS, Chaovalitwongse W, Carney PR.
Epileptic Seizure Prediction. Quantitative Neurosciences Conference at University of
Florida, February 5-7, 2003.
29. Chaovalitwongse W, Pardalos PM, Sackellares JC, Iasemidis LD, Shiau DS, Carney PR.
Nonlinear Dynamics and Global Optimization in EEG with Applications for Prediction of
Paul Richard Carney
35
Epileptic Seizures. Quantitative Neurosciences Conference at University of Florida,
February 5-7, 2003.
30. Sackellares JC, Shiau DS, Pardalos PM, Carney PR, Chaowalitwongse W. Time
Irreversibility of Brain Spatio-Temporal Dynamics at Epileptic Seizure Transitions.
International Nonlinear Sciences Conference, Vienna, Austria, February 7-9, 2003.
31. Sackellares JC, Yang MCK, Iasemidis LD, Shiau DS, Pardalos PM, Carney PR. Real –
Time Prospective Seizure Prediction and Statistical Assessment. NIH Biomedical
Information Science Technology InitiativeConsortium BISTIC, Bethesda, MD, Nov 6-7,
2003.
32. Shiau DS, Sackellares JC, Iasemidis LD, Carney PR, Pardalos PM, Chaovalitwongse W.
Dynamical Entrainment Among Epileptic Brain Areas, Ann Neurol. 2003; 54 (S7: S55).
33. Sackellares JC, Iasemidis LD, Shiau DS, Suharitdamrong W, Dance LK,
Chaovalitwongse W, Pardalos PM, Carney PR. An Automated Seizure Warning
Algorithm for Scalp EEG. Epilepsia 2003; 44 (9), 228.
34. Carney PR, Sackellares JC, Shiau DS, Iasemidis LD, Chaovalitwongse W,
Suharitdamrong W, Pardalos PM. Detection of Seizures in Newborns by Quantitative
EEG Signal Analyses. Epilepsia 2003; 44 (9) 54-55.
35. Sackellares JC, Yang MCK, Shiau DS, Iasemidis LD, Pardalos PM, Carney PR.
Prospective controlled trial of an automatic seizure prediction algorithm. . American
Academy of Neurology 55th
Annual Meeting, 2003. Neurology 60 Suppl. 1, Number 5,
2003.
36. Carney PR, Nair SP, Iasemidis LD, Shiau DS, Pardalos PM, Shenk D, Norman WM,
Sackellares JC. Quantitative analysis of EEG in the rat limbic epilepsy model. American
Academy of Neurology 56th
Annual Meeting, San Francisco, April 24-May 1, Poster
P04.016, 2004.
37. Sackellares JC, Iasemidis LD, Shiau DS, Yang CK, Dance LD, Pardalos PM, Carney
PR. Automated seizure warning system performance in temporal lobe epilepsy.
American Academy of Neurology, 56th
Annual Meeting, San Francisco, April 24-May 1,
Poster P02.033, 2004.
38. Nair SP, Shiau DS, Norman WN, Shenk D, Suharitdamrong W, Iasemidis LD, Pardalos
PM, Sackellares JC, Carney PR. Dynamical changes in the rat chronic limbic epilepsy
model. Epilepsia 45 Suppl. 7:211 (Abst. 2.060 ) , 2004.
39. Shiau DS, Iasemidis LD, Yang MCK, Carney PR, Pardalos PM, Suharitdamrong W,
Nair SP, Sackellares JC. Pattern-match regularity statistics-a measure quantifying the
characteristics of epileptic seizures. Epilepsia 45 Suppl. 7 :85 (Abst. 1.213 ) , 2004.
40. Furman, Michael; Sackellares, J. Chris; Carney, Paul; Miliotis, Abraham;
Simonotto, Jennifer; Ditto, William Phase Tracking of Moving Epileptic Foci Using EEG
and Phase-Dynamic Quantification Analysis. American Physical Society, March Meeting
2004, March 22-26, 2004, Palais des Congres de Montreal, Montreal, Quebec, Canada,
MEETING ID: MAR04, abstract #V8.008
41. Shiau DS, Sackellares JC, Iasemidis LD, Nair SP, Norman W, Carney PR. Automated
Seizure Warning in an Epileptic Rat Model. 57th Annual Meeting of the American
Academy of Neurology, Miami Fl, April, 2005. Neurology 64 Suppl. 1 (Abst. A:266),
2005.
42. Stickler DE, Valenstein E, Neiberger RE, Perkins LA, Carney PR, Shuster JJ, Theriaque
Paul Richard Carney
36
DW, Stacpoole PW. Peripheral neuropathy in genetic mitochondrial diseases. Muscle
and Nerve, 57th Annual Meeting of the American Academy of Neurology, April, 2005,
43. Shaiu DS, Iasemidis LD, Sackellares JC, Suharitdamrong W, Shenk D, Carney PR.
Quantitative methods for distinguishing neonates at risk for seizures from normal
newborns. PAS 2005: 57: 2655.
44. Furman M, Ditto W, Simmonoto J, Carney PR. High-Resolution Phase Tracking of
Moving Epileptic Foci with Phase-Dynamic Quantification Analysis. Epilepsia 46 Suppl.
8:314 (Abst. 3.113) , 2005.
45. Liu Z, Norman W, Shenk D, Carney PR, Similarity of electroencephalographic changes
in a rat model of human temporal lobe epilepsy. Epilepsia 2005; 46 (8): 292.
46. Bongiolatti S, Fennell E, Carney PR. Sleepiness as a Factor in Varying Degrees of
Behavior Problems in Children with Epilepsy. Epilepsia 46 Suppl. 8:75 (Abst. 1.176)
2005.
47. Simmonoto J, Furman, Norman W, Sanchez J, Ditto W, Carney PR. Nonlinear Analysis
of High-Resolution Microwire Electrode Data from a Chronic Limbic Epilepsy Model
over the Latent Period. Epilepsia 46 Suppl. 8:124(Abst.2.098), 2005.
48. Nair S, Shaiu D, Pardalos PD, Iasemidis L, Sackellares JC, Carney PR. Dynamical
Responses to Hippocampal Stimulation in a Rodent Model of Chronic Limbic Epilepsy.
Epilepsia 46 Suppl. 8:332 Abst. 3.163, 2005.
49. Sanchez J, Norman W, Mareci T, Carney PR. Multiscale Electrophysiological analysis
and imaging in an animal model of limbic epilepsy. Epilepsia 46 Suppl. 8:10, 2005.
50. Geyer JD, Carney PR, Gilliam F. Focal Dyshormia: Focal epileptiform spikes in
conjunction with K-complexes. Epilepsia 46 Suppl. 8:27 (Abst. 1.041), 2005.
51. Shiau DS, Liu C, Suharitdamrong W. Pardalos PM, Carney PR, Sackellares JC.
Distinguishing independent bitemporal form unilateral onset in epileptic patients by the
analysis of nonlinear characteristics of EEG signals. Epilepsia 46 Suppl. 8 :321 (Abst.
3.131), 2005.
52. Shaiu DS, Iasemidis LD, Sackellares JC, Suharitdamrong W, Shenk D, Carney PR.
Quantitative methods for distinguishing neonates at risk for seizures from normal
newborns. PAS 2005: 57: 2655.
53. Shiau DS, Nair SP, Iasemidis LD, Carney PR, Norman
W, Principe JC, Pardalos PM,
Suharitdamrong W, Cho J, Sackellares JC. Seizure warning and dynamic response to
electrical stimulation in a rodent model of chronic limbic epilepsy. 2005; IEEE EMBC.
54. Singh T, Little LE, Nathoo S, Snively C, Ringdahl D, Winger K, Jackson C, Carney PR,
Liu Z, Borum P. Evaluating potential growth abnormalities in a patient population.
Annual Meetings of the American Epilepsy Society and Canadian League Against
Epilepsy, 2006.
55. Snively C, Carney PR, Liu Z, Ringdahl D, Winger K, Jackson C,
Singh T, Little LE,
Borum PR. Developing an Evidence-Based Ketogenic Therapy Program for Treatment
of Epilepsy. Annual Meetings of the American Epilepsy Society and Canadian League
Against Epilepsy, 2006.
56. Sepulveda H, Hoang-Minh L, Parekh MB, Hadlock A, Norman W, Sanchez JC,. Ditto
WL, Carney PR, Mareci T. Evolution of Temporal Lobe Epilepsy Observed with 11.1
Tesla MRI In Vivo. 60th Annual Meeting of the American Epilepsy Society, San Diego,
CA, 2006.
Paul Richard Carney
37
57. Parekh M, Hoang-Minh LB, Sepulveda H, Haddock A, Norman W, Sanchez JC, Ditto
WL, Carney PR, Mareci TH. Diffusion Tensor MR Imaging of the Rat Model of Mesial
Temporal Lobe Epilepsy. 60th Annual Meeting of the American Epilepsy Society, San
Diego, CA, 2006.
58. Nair SP, Norman WM, Dance L, Pardalos PM, Principe J, Carney PR. Development of
Spatiotemporal Dynamical Transitions during Epileptogenesis. 60th Annual Meeting of
the American Epilepsy Society, San Diego, CA, 2006.
59. Zhang Q, Zhao Z, Liu, Carney PR, Jiang H. Imaging of Seizure-Onset Zone with Non-
Invasive Photoacoustic Tomography in a Rat Model of Focal Seizures. 60th Annual
Meeting of the American Epilepsy Society, San Diego, CA, 2006.
60. Hoang-Minh L, Sepulveda H, Parekh M, Hadlock A, Norman W, Sanchez JC, Ditto WL,
King MA, Carney PR, Liu Z, Mareci T. MRI Measurements at 17.6 Tesla in an Animal
Model of Mesial Temporal Lobe Epilepsy Correlated with Histological Analysis. 60th
Annual Meeting of the American Epilepsy Society, San Diego, CA, 2006.
61. Bongiolatti SR, Fennell EB, Carney PR. Sleep Fragmentation and Disruptive Behaviors
in Children with Epilepsy and Co-morbid Sleep Disordered Breathing. Journal of the
International Neuropsychological Society 2006; 12(S1): 109.
62. Zhang Q, Liu L, Carney PR, Jiang H. Imaging of Seizure-Onset Zone with Non-Invasive
Photoacoustic Tomography in a Rat Model of Focal Seizures. 60th Annual Meeting of the
American Epilepsy Society, San Diego, CA, 2006.
63. Parekh MB, Hoang-Minh L, Sepulveda H, Handlock A, Norman W, Sanchez, JC Ditto
WL, Carney PR, Mareci TH. Diffusion Tensor MR Imaging of the Rat Model of Mesial
Temporal Lobe Epilepsy. 60th Annual Meeting of the American Epilepsy Society, San
Diego, CA, 2006.
64. Geyer JD, Carney PR, Dillard SC. Epilepsy and Restless Legs Syndrome. 60th Annual
Meeting of the American Epilepsy Society, San Diego, CA, 2006.
65. Martynyuk, AE, Carney PR, Dennis DM, Laipis PJ. Mechanisms of Epileptic Activity in
Phenylketonuria: Decreasing Levels of Phenylalanine Trigger Seizures. 60th Annual
Meeting of the American Epilepsy Society, San Diego, CA, 2006.
66. Loomis-Roux AR, Smith-Bonahue T, Carney PR. School Adjustment in Children with
Epilepsy: Examining Parent Perceptions. 60th Annual Meeting of the American Epilepsy
Society, San Diego, CA, 2006.
67. Zhang Q, Liu Z, Jiang H, Carney PR. Imaging of epilepsy using photoacoustic
tomography. 60th Annual Meeting of the American Epilepsy Society, San Diego, CA,
2006.
68. Sanchez JC, Liu Z, Carney PR. Identifying the seizure onset zone using amplitude
modulated slow potentials, gamma, fast gamma, and neural ensemble activity. 60th
Annual Meeting of the American Epilepsy Society, San Diego, CA, 2006.
69. Geyer JD, Carney PR, Dillard SC, Parrish P. Anti-depressant Medications, Neuroleptics
and Prominent Eye Movements During. Sleep, Vol 29 Abstract Suppl 2006 p.A34.
70. Zhang QZ, Liu Z, Carney PR, Jiang HB, Imaging epilepsy using finite-based
photoacoustic tomography: Initial in vivo results. Optical Society America Annual
Meeting, Lauderdale, FL 2006.
71. Singh, T, Little, LE, Nathoo S, Carney PR, Borum PB. Evaluating potential growth
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abnormalities in a patient population at Shands/UF on ketogenic therapy for seizures.
Experimental Biology Meeting, 2006.
72. Sanchez JC, Gunduz A, Carney PR, Principe JC. Extraction and localization of
mesoscopic motor control signals for human ECoG neuroprosthetics. Neuroplasticity
Conference, 2006.
73. Sanchez JC, Principe JC, Carney PR. Choosing the Appropriate Level of Abstraction
for Brain Machine Interfaces: Data Collection and Analysis Insights. DIMACS Workshop
on Data Mining, Systems Analysis, and Optimization in Neuroscience, Feb 15-17, 2006.
74. Carney PR. Dynamical EEG Properties in the Limbic Epilepsy Rat Model. DIMACS
Workshop on Data Mining, Systems Analysis, and Optimization in Neuroscience, Feb 15-
17, 2006.
75. Bongiolatti SR, Fennell EB, Carney PR. Sleep Fragmentation and Disruptive Behaviors
in Children with Epilepsy and Co-morbid Sleep Disordered Breathing, International
Neuropsychological Society, Boston, MA, Feb. 3-6, 2006. 2(S1):109, 2006.
76. Hwang Dong-UK, Talathi S, Carney PR, Ditto W, Myers S, Norman W, Simonotto J.
High frequency oscillations in the limbic rat model of temporal lobe epilepsy, J.
Computational Neuroscience, 2007.
77. Bing J, Vermuri BC, Ozarslam E, Carney P, Mareci T A novel tensor distribution for the
diffusion weighted MR signal. IEEE International Symposium on Biomedical Imaging:
From Nano to Macro. April 12-17, 2007.
78. Talathi SS, Carney, PR, Dong-Uk Hwang, Ditto W, Myers S, Simonotto J. High
frequency oscillations in rat model of chronic limbic epilepsy, CNS, Toronto, Canada,
July 2007.
79. Carney PR, Cadotte AJ, Ditto WL, Mareci T, DeMarse TB, Temporal Lobe Epilepsy:
Anatomical and Effective Connectivity, Conference on Computational Neuroscience (Feb
2008) Gainesville, FL.
80. Cadotte AJ, DeMarse TB, Ditto WL, Carney PR, Granger Causality Analysis of
Spontaneous Seizure in an Animal Model of Temporal Lobe Epilepsy, Pediatric Science
Days, Univ of Florida (March 2008) Gainesville, FL.
81. Cadotte AJ, DeMarse TB, Mareci T, Talathi S, Hwang DU, Ditto W, Carney PR,
Granger Causality Analysis of Spontaneous Seizure in an Animal Model of Temporal
Lobe Epilepsy, Gordon Research Conference- Mechanisms of Epilepsy and
Synchronization (Aug 2008) Waterville, ME.
82. Talathi SS, Dong-Uk Hwang, Ditto WL, Spano ML, Sepulveda H, Mareci T, Carney PR.
Chronobiology of epilepsy, Nature, 2008.1679.1, 2008.
83. Talathi SS, Dong-Uk Hwang, Ditto W, Carney PR. Loss of balance and circadian phase
reversal in an animal model of limbic epilepsy, IEEE BMES, St Louis.
84. Dong-Uk Hwang, Talathi SS, Winters J, Ditto W, Carney PR. Controlling firing activity
of population spikes during epileptogenesis in an animal model of temporal lobe
epilepsy, IEEE BMES, St Louis.
85. Geyer JD and Carney PR. The association between acute cerebral infarction and
restless legs. American Academy of Neurology 60th
Annual Meeting, Chicago, April 12-
19, 2008, Scientific Abstract Number 1548, Poster number P05.170.
86. Kumar R, Barmpoutis A, Vemuri BC, Carney PR, Mareci TH. Multi-fiber reconstruction
Paul Richard Carney
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from DW-MRI using a continuous mixture of von mises-fisher distributions. IEEE Conf.
on Mathematical Methods for Biomedical Image Analysis. June, 2008.
87. Zafar R and Carney PR. Gene therapy for temporal lobe epilepsy: the role of adeno
associated viral vector delivered somatostatin. Soc for Neuroscience Annual Meeting,
Platform, Wash D.C. 2008.
88. Cadotte A. DeMarse T, Carney PR. Analysis of spontaneous temporal lobe seizures
using granger causality. Soc for Neuroscience Annual Meeting, Platform, Wash D.C.
2008.
89. Parekh MB, Sepulveda, Hoang King M, Mareci T, Carney PR. Diffusion tensor MR
imaging of a rat model of temporal lobe epilepsy. 38th Annual Meeting, Society for
Neuroscience 15-19 Nov 2008. Epilepsy: Circuits and Therapy.
90. Zafar R, Carney PR. Adeno associated viral vector delivered somatostatin as a
candidate for gene therapy for temporal lobe epilepsy. 62nd Annual Meeting of the
American Epilepsy Society, Biennial North American Regional Epilepsy Congress,
December 8, 2008 Platform Session #: A.08.
91. Cadotte A, DeMarse T, Ditto W, Carney PR. In vivo causal analysis of initiation,
propagation and termination of spontaneous temporal lobe seizure. 62nd Annual Meeting
of the American Epilepsy Society, Biennial North American Regional Epilepsy Congress,
December 8, 2008 Platform Session #: A.03
92. Talathi SS, Hwang DU, Cadotte A, Ditto WL, Carney PR. Imbalance in hippocampal
network synchrony during epileptogenesis. 62nd Annual Meeting of the American
Epilepsy Society, Biennial North American Regional Epilepsy Congress, December 6,
2008 Poster Session IW.O3.
93. Kantorovich, S, Astary GW, Parekh M, Mareci TH, Sarntinoranont M, Carney PR.
Convection enhanced delivery as a local anit-convulsant delivery method for the
treatment of epilepsy. Soc for Neuroscience Annual Meeting, Chicago, 2009.
94. Zafar R, King MA, Frazier CJ, Carney PR. Adeno-associated viral vector delivered
somatostatin as a neuroprotective agent for temporal lobe epilepsy. Soc for Neuroscience
Annual Meeting, Chicago, 2009.
95. Parekh MB, Triplett WT, King MA, Mareci TH, Carney PR. Early damage in the
parahippocampal gyrus after status epilepticus as a structural signature for the
development of spontaneous seizures-a longitudinal study using enhanced MRI. Soc for
Neuroscience Annual Meeting, Chicago, 2009.
96. Talathi SS, Hwang DU, Ditto WL, Carney PR. Circadian control of neural excitability in
an animal model of temporal lobe epilepsy. 61st Annual Meeting of the American
Academy of Neurology, 2009.
97. Talathi SS, Hwang
DU, Miliotis A, Carney
PR, Ditto
WL. Synchrony with Shunting
Inhibition. Eighteenth Annual Computational Neuroscience Meeting CNS 2009.
98. Astary GW, Kantorovich S, Parekh MB, Triplett WT, Carney PR, Mareci TH,
Sarntinoranont M. Regional convention-enhanced delivery of gadolinium-labeled
albumin in the rat hippocampus in vivo. BMES, 2009.
99. Myers S, Talathi S, Carney PR. Determining the firing rate of interictal population
spikes leading to seizures. 2.102, 63rd
Annual Meeting of the American Epilepsy Society,
Boston, MA, 2009.
Paul Richard Carney
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100. Zhou J, Talathi S, Cadotte A, Liu Z, Holmes G, Carney PR. The effects of
hippocampus CA1 single neuron firing properties on interictal spike patterns during onset
in a rat model of temporal lobe epilepsy. 3.330, 63rd
Annual Meeting of the American
Epilepsy Society, Boston, MA, 2009.
101. Talathi S, Nandan M, Ditto W, Khargonekar P, Carney PR. Support vector machine
algorithms for early seizure detection in an animal model of temporal lobe epilepsy.
3.242, 63rd
Annual Meeting of the American Epilepsy Society, Boston, MA, 2009.
102. Cadotte A, Talathi S, Zhou J, Myers S, Hwang D, Ditto W, Carney PR. Analysis of
hippocampal interdependencies for early seizure detection. 3.067, 63rd
Annual Meeting of
the American Epilepsy Society, Boston, MA, 2009.
103. Sarntinoranont, M., Kim, J.H., Carney, P.R., and Mareci, T.H. Diffusion Tensor
Imaging- based Computational Models of Convection-Enhanced Delivery. 6th Annual
World Congress of the International Brain Mapping & Intraoperative Surgical Planning
Society (IBMISPS), Boston, MA, August 26-29, 2009.
104. Astary, G.W., Kantorovich, S., Parekh, M.B., Carney, P.R., Mareci, T.H and
Sarntinoranont, M. Convection Enhanced Delivery of an MR Contrast Agent to the
Dorsal and Ventral Hippocampus. 2009 BMES Annual Meeting, Pittsburgh, PA, October
7-10, 2009.
105. Cadotte A, Parekh M, Triplett W, Talathi S, Mareci T, Carney P. Integration of structure,
behavior, and function for temporal lobe epilepsy: Evidence for future directions for
exploration of ictogenic and epileptogenic transitions. American Clinical
Neurophysiology Society, Annual Meeting Feb 2-7, 2010, San Diego, CA, Poster and
Abstract B109.
106. Ratnadura S, Talathi SS, Carney PR, Pramod P. Khargonekar PP. Synchronization
induced by signal propagation delays in inhibitory networks. Nineteenth Annual
Computational Neuroscience Meeting July 24-30, 2010, San Antonio, Texas.
107. Talathi SS, Ratnadura S, Kantorovich S, Carney PR, Khargonekar PP. Control of neural
synchrony with light-activated opsins. Nineteenth Annual Computational Neuroscience
Meeting July 24-30, 2010, San Antonio, Texas.
108. Kim, J.H., Astary, G., Kantorovich, S., Mareci, T.H., Carney, P., Sarntinoranont, M.
Measurement of In Vivo Tracer Distribution during CED in the Rat Brain using DCE-
MRI. 37th
Annual Mtg and Expo of the Controlled Release Society, Portland, OR, July
10-14, 2010, accepted.
109. Luis Colon-Perez, William Triplett, Stephen Eisenscheck, Paul Carney, Thomas Mareci.
Fiber tracking the cingulum in the human brain using a novel statistical model of water
diffusion measured with MRI. University of Florida College of Medicine Research Day.
04/24/10.
110. Mansi Parekh, William Triplett, Paul Carney, Thomas Mareci. White Matter
Reorganization in a Rat Model of Temporal Lobe Epilepsy Observed using Enhanced
MRI. University of Florida College of Medicine Research Day. 04/24/10.
111. Garrett Astary, Svetlana Kantorovich, Jung Hwan Kim, Sung Jin Lee, Tatiana Nobrega,
Mansi Parekh, William Triplett, Paul Carney, Thomas Mareci, Malisa Sarntinoranont.
Convection-Enhanced Delivery for the Potential Delivery of Therapeutic Agents for the
Treatment of Epilepsy. University of Florida College of Medicine Research Day
04/24/10.
Paul Richard Carney
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112. Svetlana Kantorovich, Philip Barish, Sachin Talathi, Shivakeshavan Ratnadurai, Junli
Zhou, Stephen Myers, William Ogle, Pramod Khargonekar, Paul Carney. Control of
hippocampal neural activity using optical stimulation. University of Florida College of
Medicine Research Day. 04/24/10.
113. Allen H, Lee
K, Jones
L, Andrade
E, Carney
P, Liu
Z, Borum
P. Ketogenic Therapy
Education Modules for Caregivers and Healthcare Professionals. Experimental Biology
2010 in Anaheim CA.
114. Kantorovich S., Astary, G., Parekh M.B., Mareci T.H., Sarntinoranont M., Carney P.
Status epilepticus affects hippocampal structure and infusate distribution
profiles. Neuroscience 2010. San Diego CA, Nov 13-17th, 2010, submitted.
115. Cadotte A, Myers S, Parekh M, Talathi SS, Mareci T, Carney PR. Slow changes during
epileptogenesis in a spontaneously seizing animal model of temporal lobe epilepsy.
American Epilepsy Society 64th
Annual Meeting Dec 3-7, 2010.
116. Talathi SS, Zhao J, Cadotte A, Carney PR. Circadian rhythm of core body temperature
in an animal model of chronic epilepsy. American Epilepsy Society 64th
Annual Meeting
Dec 3-7, 2010.
117. Zhen Yuan, R. Jiang, L. Ji, J. Zhou, P. Carney, H. Jiang. Combining Granger causality
and diffuse optical tomography to investigate the effective connectivity in temporal lobe
epilepsy. Poster No. 3.235. American Epilepsy Society 64th
Annual Meeting Dec 3-7,
2010.
118. Qizhi Zhang, B. Hu, Z. Yuan, J. Zhou, P. Carney, H. Jiang. High temporal resolution
photoacoustic imaging for seizure localization and network mapping. Poster No. 3.172
American Epilepsy Society 64th
Annual Meeting Dec 3-7, 2010.
119. Ruixin Jiang, Z. Yuan, Q. Zhang, L. Ji, J. Zhou, P. Carney, H. Jiang. Noninvasive
imaging of epilepsy using fast diffuse optical tomography. Poster No. 3.157. American
Epilepsy Society 64th
Annual Meeting Dec 3-7, 2010.
120. Andrade E, Liu Z, Eisenschenk S, Cibula, SJ, Goldsmith I, Parekh M, Triplett W,
Cadotte A, Mareci T, Carney PR. 3T Brian MRI and Ictal Findings of patients with
nonlesional partial epilepsy refractory to medical treatment. American Epilepsy Society
64th
Annual Meeting Dec 3-7, 2010.
121. Alex Cadotte, S. Myers, M. Parekh, S. Talathi, T. Mareci and P. Carney. Slow changes
in functional connectivity during epileptogenesis in a spontaneously seizing animal model
of temporal lobe epilepsy. 1.056 American Epilepsy Society 64th
Annual Meeting Dec 3-7,
2010.
122. Astary GW, Kantorovich S, Carney PR, Sarntinoranont M, Mareci TH. Gd-albumin
relaxivity in the rat thalamus at 11.1T. ISMRM 2011 Annual Meeting.
123. Talathi SS, Carney PR. Khargonekar PP. In-phase neural synchrony through optical
stimulation. Poster No. 44.10/H38. 2010 Neuroscience. San Diego, CA: Society for
Neuroscience, 2010. Online.
124. Twyford P. DeMarse T, Barish P, Ogle W, Carney PR. Spatiotemporally precise
optical system for controlling neural activity in vitro. Poster No. 816.1/NNN22. 2010
Neuroscience San Diego, CA: Society for Neuroscience, 2010.
Paul Richard Carney
42
Selected Invited Talks at Regional, National and International Meetings
1. Evaluation and Treatment of the Seizing Child, University of Florida, Emergency Medicine
Clinical Lecture, August, 1998
2. Cephalon, Inc., Speaker Bureau on Sleep Disorders
3. Pediatric epilepsy surgery; evaluation and management, University of Florida pediatric
nursing in-service, August, 1998
4. Sleep Disorders. East Side Community Health Center: Florida representative Karen Chestnut,
Acute repetitive seizures and other epileptic emergencies: management strategies, University
of Florida, Department of Pediatrics, September, 1998,
5. Temporal lobe epilepsy surgery during childhood. Neurology Grand Rounds, State
University of New York, Buffalo, NY, February, 1998
6. University of Michigan, Ann Arbor, Pediatric Resident’s Noon Conferences 1999
7. University of Florida College of Medicine medical student and pediatric house officer rural
medicine expedition and course (Nicaragua). Group leader: Donald Eitzman, M.D., February,
1999
8. Update on Epilepsy: Consensus Conference in Child Neurology, Orlando, Fl, Management of
medically refractory seizures, University of Florida, Department of Pediatrics, February, 1999
9. University of Valparaiso School of Medicine, Department of Cell Biology, Neuroscience
Lecture series, Director: E. Couve, 1990-92
10. Health in a Heartbeat radio program on WUFT-FM (Classic 89), Topic: Spinal muscular
dystrophy, February, 2000
11. Public Relations, A Question of Health” TV 20, Theme: Sleep Disorders, Panel Member,
January, 2000
12. University of Florida/Shands Hospital Epilepsy Surgery Patient Reunion, Invited Speaker,
Topic: New Anticonvulsant Drugs, September, 2000
13. Children’s Miracle Network, TV 20, PersonalPortrait: Sara Higgins. Story reviews the
personal experience of an 8-year-old child with refractory epilepsy undergoing a presurgical
and surgical evaluation for epilepsy surgery, June, 2001
14. American Epilepsy Society Annual Meeting, Special Interest Group and Participatory
Roundtable, New Orleans, LA. Topic: Brain Dynamics in Rat Chronic Limbic Epilepsy
Model, 2001
15. Children’s Miracle Network, Radio Telethon Fund Raiser. Interview reviews medical needs
of children with complex neurologic problems, including epilepsy, sleep disorders, and
developmental delay, August, 2001
16. Predictability of seizures in a transgenic epilepsy-prone mouse model, Spring Epilepsy
Research Conference, Cayman Islands, Platform session, April, 2001
17. Sleep disordered breathing during childhood: diagnosis and treatment, Nemours Children
Foundation Grand Rounds, Jacksonville, March, 2001
18. Practical Approach to the Diagnosis and Management of Sleep Disorders, North Florida
Neurological Society, February 13, 2002
19. Recent Advances in Modeling and Prediction of Epileptic Seizures, Grand Rounds,
Department of Neurology, Case Western Reserve University, Cleveland, OH, March 1, 2002
20. Biomedical Research Partnership seminar series. Colleges of Medicine and Biomedical
Engineering. University of Florida. Talk: Seizure prediction in the H218 sphingosine 1-
phosphate mouse model. January 15, 2002
Paul Richard Carney
43
21. Practical Approach to the Diagnosis and Management of Sleep Disorders, North Florida
Neurological Society, February 13, 2002
22. University of Chile and University of Valparaiso, Chilean Pediatric Neurology Society,
Valparaiso, Chile, 1st International Iberoamerican Pediatric Neurology Conference, Topics:
Childhood Epilepsy and “Childhood Sleep Disorders, March, 2003
23. Seizure Prediction and Substrates for Seizure Prediction Platform, Topic; Seizure prediction
by nonlinear time series analyses of brain electrical activity. April 23, 2003
24. Florida Chapter AAP Annual Meeting and Florida Pediatric Alumni Association Annual
Meeting, Topic: “Recent Advances in the Diagnosis and Treatment of Pediatric Epilepsy”.
June 20, 2003
25. The First International Collaborative Workshop on Seizure Prediction, International Seizure
Prediction Group, Bonn, Germany. Topic: Seizure Prediction in a Generalized Epilepsy
Animal Model, March, 10, 2003
26. Grand Rounds, University of Florida, Department of Pediatrics, Jacksonville, FL, Title:
Catastrophic Childhood Epilepsy: Advances in Diagnosis and Management, April, 23, 2004
27. Grand Rounds, University of Arkansas, Department of Pediatrics. Topic: Modeling and
Seizure Prediction, May 12, 2004
28. Conference on Data Mining in Biomedicine, Center for Applied Optimization, Modeling and
Computation for Engineering, Science and Industry, College of Engineering, University of
Florida, Gainesville, Topic: A Quantitative EEG Method for real-time Detection of Neonatal
Seizures in the Neonatal Intensive Care Unit. February 16-18, 2004
29. Quantitative Neuroscience/Neural Engineering Seminar, University of Florida, Neonatal
Seizures, March 2, 2004
30. Children’s Medical Services, Nursing Symposium, Topic: Childhood Sleep Disorders:
Evaluation and Management, April, 2004
31. University of Valparaiso, Society for Pediatric Neurology, Topics: Phamacoresistant
Childhood Epilepsy and Evaluation and Treatment of Sleep Disorders, June, 2004
32. American Academy of Neurology, Miami, FL, Topic: Seizure Prediction in a Limbic Model
of Temporal Lobe Epilepsy, May 2, 2005
33. Research Seminar Grand Rounds, Department of Physical Medicine and Rehabilitation,
University of Florida, Gainesville, FL Topic: Brain Machine Interface for Epilepsy,
September 14, 2005
34. Chilean Pediatric Society, Chile, 1st International Iberoamerican Pediatric Neurology
Conference, Topics: Childhood Epilepsy and Childhood Sleep Disorders, October, 2005
35. Conference on Systems Analysis, Data Mining, and Optimization in Biomedicine, Topic:
Dynamical Characteristics in Rat Chronic Limbic Epilepsy Model, February 2-4, 2005
36. Neuroscience Grand Rounds, Topic: Pathophysiology of Temporal Lobe Epilepsy, University
of Florida, February 5, 2006
37. Conference on Data Mining, Systems Analysis and Optimization in Neuroscience University
of Florida. http://www.ise.ufl.edu/cao/neuroscience2006/ Topic: EEG Dynamics in an
Animal Model of Temporal Lobe Epilepsy, February 15-17, 2006.
38. College of Engineering Recruitment, University of Florida, Gainesville, FL Topic: Brain
Dynamics and Neural Networks in Epilepsy, February 17, 2006
39. 4th International Sleep Disorders Forum Rome, Italy, 7-8 September, 2006
Paul Richard Carney
44
40. DIMACS Workshop on Data Mining, Systems Analysis, and Optimization in Neuroscience,
Gainesville, FL, Topic: Dynamical EEG Properties in the Limbic Epilepsy Rat Model,
February 15-17, 2006
41. Florida Neurological Society, Topic: Epilepsy Behavioral and Cognitive CoMorbidity in
Pediatric Epilepsy: Recognition, Mechanisms, Assessment and Treatment., Orlando, Florida,
December 14, 2006
42. 23rd
Congreso de Psiquiatria y Neurologia de la Infancia y la Adolescencia. Topics:
Seizure Prediction; Emerging Technologies for Epilepsy: Diffusion Tensor Imaging and
Photoacoustic Tomography. Viña del Mar, Chile, South America, October 12-14, 2006
43. 60th
Annual Meeting of the American Epilepsy Society, Sensing the Brain; Engineering
Special Interest Group, Topic: Neural Prosthetic for Epilepsy, , San Diego, CA. December 1,
2006
44. 4-D Neuroimaging 2rd
Annual International Users Group Meeting, Denver, June 6-8, 2007
45. Data Mining, Systems Analysis & Optimization in Biomedicine University of Florida College
of Engineering, March 28-30, 2007
46. Neural Interface for Repair and Treatment: Potential for Epilepsy, Mt Sinai School of
Medicine, New York, NY, September 17, 2007
47. Third International Seizure Prediction Workshop, Talk: Dynamics of a Limbic Epilepsy
Model, Freiburg, Germany. September 30-October 4, 2007
48. International Conference on Translational Research, Peking Union Medical College
Hospital (PUMC), Topic: Neural Interface for Repair and Treatment: Potential for Epilepsy.,
Beijing, China, November 11-13, 2007
49. State Key Laboratory of Brain and Cognitive Science Institute of Psychology, Chinese
Academy of Sciences.. Topic: Sleep disorders in children and adults. Beijing, China,
November. 15, 2007
50. Capital Medical University Beijing Tiantan Hospital. Topic: Brain Machine Interface for
Epilepsy. Beijing, China, November 15, 2007.
51. Neural Interface for Repair and Treatment: Potential for Epilepsy, University of Florida
Department of Neuroscience, January 16, 2008
52. Conference on Computational Neuroscience 2008. Topic: Temporal Lobe Epilepsy:
Anatomical and Effective Connectivity. University of Florida, Center for Applied
Optimization, Gainesville FL February 20, 2008
53. American Association of Critical-Care Nurses. Swamped with Knowledge 2008. Topic: To
Seize or Not to Seize: That is the Question, Gainesville, Florida, March 1, 2008
54. XXIX Annual Child Neurology Postgraduate Course Miami Children’s Hospital. Topics:
Sleep and Epilepsy and Epilepsy Co-Morbidity. Miami, Florida. May 2, 2008
55. 7th Curso International de Neuropsiquiatria Infantile. Viña del Mar, Chile, May 30-31, 2008.
56. 4-D Neuroimaging 3rd
Annual International Users Group Meeting, , Barcelona, Spain, July
13-15, 2008
57. Neural Interface for Repair and Treatment: Potential for Epilepsy, Grand Rounds, Emory
University/Georgia Tech, Atlanta, Department of Neuroscience, September 9, 2008
58. Biomedical Engineering Update: University of Florida College of Engineering, Department
of Biomedical Engineering Advisory Board Meeting, October 17, 2008
59. Neural Interface for Repair and Treatment of Epilepsy, Department of Neurology Grand
Rounds, Wake Forest University, December 15, 2009.
Paul Richard Carney
45
60. Optogenetics Deconstruction of Hippocampus Epileptic Neural Circuitry. American Clinical
Neurophysiology Society, Annual Meeting San Diego, CA, Feb 2-7, 2010
61. Circadian Regulation of Neural Excitability in Temporal Lobe Epilepsy. Nocturnal Frontal
Lobe Epilepsy: An Interdisciplinary Perspective. National Institutes of Health Office of Rare
Diseases Research and Alliance for Epilepsy Research. Sanibel Symposium. Sanibel, FL,
Feb 11-12, 2010
62. Grand Rounds, Curing Epilepsy: Progress and Future Directions, Medical College of
Milwaukee, Milwaukee, WI Dec 13, 2010
63. Grand Rounds, Epilepsy: From Bench to Bedside, University of Florida Department of
Pediatrics, Dec 17, 2010
Selected Articles/Interviews
“Spinal muscular dystrophy”, Health in a Heartbeat radio program on WUFT-FM (Classic
89), 6/1999
“A Question of Health”, Public Relations, TV 20, Theme: Sleep Disorders, Panel Member,
01/2000
“Medical needs of children with complex neurologic problems, including epilepsy, sleep
disorders, and developmental delay”. Children’s Miracle Network, Radio Telethon Fund
Raiser. 8/2001
“Story reviews the personal experience of an 8 year-old child with refractory epilepsy
undergoing a presurgical and surgical evaluation for epilepsy surgery”, Children’s Miracle
Network, TV 20, Personal Portrait:. 6/2001
“Hannah Beth’s Story”, Channel 20 TV (Sarasota, FL) news interview on mitochondrial
disorders in children, 7/2004
“UF tries out mind-controlled computers”. Gainesville Sun, July 31, 2004
“Childhood Sleep Disorders”, University of Florida College of Journalism, 2/2004
“Mathematical Analysis of EEG May Lead To Quicker Diagnosis”. Epilepsy Action feature
story, 2005
“New Brain Monitoring Method Would Pinpoint Babies at Risk for Seizure”, Medgadgets
feature Story, 2005
“Sleep Disorders in Children with Epilepsy: More Common than You Think”, Feature Story
Epilepsy.com, 2005
“Epilepsy - New brain monitoring method would pinpoint babies at risk for seizures”.
Epilepsy News today feature story, 2005
“Solving sleep problems helps epileptic children”, University of Florida feature story, March
30, 2005.
“UF researchers explore epilepsy, sleep problems”, Feature story Gainesville Sun, April 18,
2005
Paul Richard Carney
46
“Confusion and speech problems are frequent signs of seizures, but babies offer few such
clues as to what ails them”, UF feature story Tuesday, 17-May-2005 AZoMed.com, 2005
“Epilepsy Surgery”, Children’s Miracle Network feature story, 2005
“Recreating Epilepsy”, University of Florida College of Engineering feature story, 2006
“Convention Enhanced Delivery in Epilepsy”, University of Florida Foundation Feature
Story, Nov, 2009.
http://www.floridatomorrow.ufl.edu/gallery/video_galleries/Initiatives/Eng_Neuro_Thera_Vi
deo.htm
Neural Interface Technology. University of Florida Biomedical Engineering Society seminar.
Feb 7, 2010.
“Monsters in My Head”. Animal Planet, Medical Detective Work,
http://animal.discovery.com/ August 25, 2010.
“Reflex Epilepsy: Features in The Body Odd on msnbc.com http://bodyodd.msnbc.msn.com/,
The Press-Enterprise.com http://topics.pe.com Zacquisha http://zacquisha.com September 20,
2010.