Educational objEctivEsParticipants will learn the current classifications and diagnostic criteria for tumors and tumor-like lesions of the selected sub-specialty areas, including both common and unusual entities. The appropriate use of ancillary diagnostic techniques will be highlighted. Complete differential diagnoses will be discussed, and a practical, problem-oriented approach to the pathologic evaluation of specimens will be emphasized. Participants will learn about the clinical features of the various tumor entities along with pathologic and molecular prognostic factors and predictors of therapeutic responsiveness.

Goals of thE coursEThe purpose of this course is to review in depth selected topics in the pathology of neoplastic diseases, with an emphasis on clinical features, diagnostic criteria including the use of novel diagnostic modalities when applicable, prognostic factors, and assessment of therapy-related factors.

coursE dEsiGnThis course consists of didactic lectures with question and discussion periods as well as case presentations and interactive slide seminars. The lectures are organized by the specific sub-specialties to be covered this year, with 1-2 days devoted to each of three areas (gastrointestinal pathology, genitourinary pathology and thoracic pathology).

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summaryThis four and one half day course will provide an up-to-date review of the pathology of selected sub-specialty areas of neoplastic disease, including gastrointestinal, genitourinary and thoracic pathology. Appropriate use of advanced diagnostic techniques such as immunohistochemistry and molecular pathology will be incorporated into the lectures, including the assessment of therapeutic biomarkers. Case presentations will also be integrated into some sessions. Finally, more intimate, interactive slide seminar sessions on selected topics in breast, gastrointestinal, genitourinary and thoracic will be available (registration is limited, additional fees apply). The Department of Pathology at Memorial Sloan Kettering Cancer Center has produced a course on the Surgical Pathology of Neoplastic Diseases for over 30 years. With the 35th edition, we continue to expand the scope of the course to reflect the increasing contributions of cytopathology, immunopathology, and molecular pathology. The course faculty will include the attending pathology staff from Memorial Sloan Kettering Cancer Center along with selected clinical faculty. Course participants will receive a complete syllabus within our new CME portal, along with digitized glass slides of cases for review. The course will be held on the campus of Memorial Sloan Kettering Cancer Center on the Upper East Side of Manhattan, a vibrant and safe neighborhood within easy access of the widely varied cultural attractions of New York City. A full breakfast and lunch will be provided daily.

audiEncEThis course is directed toward practicing pathologists, both in academic and private practice environments, as well as residents and fellows in pathology, who wish to broaden their understanding of neoplastic diseases.

accrEditation statEmEntMemorial Sloan Kettering Cancer Center is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

ama crEdit dEsiGnation statEmEntMemorial Sloan Kettering Cancer Center designates this live activity for a maximum of 32.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

sElf assEssmEnt modulEs (sams)This program will include 20 SAM Credits.

locationMemorial Sloan Kettering Cancer CenterRockefeller Research Laboratories Auditorium430 East 67th StreetBetween First and York AvenuesNew York, NY 10065Phone: 212-639-5696Fax: 212-557-0773E-mail: cooks@mskcc.org

The Pathology of Neoplastic Diseases | April 29 - May 3, 2019

EARLY* GENERAL$1000 $1100 MDs, PhDs and DOs $650 $750 Residents and Fellows** *Deadline is April 1, 2019.

**A reduced rate of $650 ($750 after 4/1/19) is offered to pathologists-in-training; the registration must be accompanied by a letter from the residency or fellowship program director certifying the applicant's status. Optional slide seminars are offered for an additional fee of $50 each. Seating is limited.

Optional slide seminar: Thoracic Pathology (Mon. 4/29) Gastrointestinal Pathology (Weds. 5/1) Genitourinary Pathology (Thurs. 5/2)

Registration fees include attendance at the course, handout materials, and meals. Written notice of cancellation must be received no later than April 1, 2019. Refunds are subject to a $65 administrative charge and will be processed after the conference. For more information, please contact the CME office at 646-227-2025, Fax: 212-557-0773, Address: 633 Third Avenue, 12th FL, New York, NY 10017 or via e-mail cme@mskcc.org.

Please visit: www.mskcc.org/neoplasticdiseases to register or for more information.

rEGistration notEs

The Pathology of Neoplastic Diseases | April 29 - May 3, 2019

Monday, April 29, 2019

7:50-8:00 Opening remarks Meera R. Hameed, MD

8:00-8:45 Lung CanCer CLassifiCatiOn William D. Travis, MD

8:45-9:30 mOLeCuLar pathOLOgy Of Lung CanCer Jason C. Chang, MD

9:30-10:00 Break

10:00-10:45 emerging issues in Lung adenOCarCinOma William D. Travis, MD

10:45-11:30 immunOhistOChemistry fOr Lung tumOr diagnOsis and BiOmarker testing: an update Natasha Rekhtman, MD, PhD

11:30-12:15 diagnOsis Of Lung CanCer in CytOLOgy and smaLL BiOpsies Darren J. Buonocore, MD

12:15-1:30 LunCh

1:30-2:15 neurOendOCrine tumOrs Of the Lung Natasha Rekhtman, MD, PhD

2:15-3:00 pLeuraL tumOrs – part 1 Jennifer L. Sauter, MD

3:00-3:30 Break

3:30-4:15 frOzen seCtiOn diagnOsis Of thOraCiC tumOrs Darren J. Buonocore, MD

4:30-6:00 sLide seminar Jennnifer L. Sauter, MD, Jason C. Chang, MD, Darren J. Buonocore, MD

Tuesday, April 30, 2019

8:00-8:45 pLeuraL tumOrs – part 2 Jennifer L. Sauter, MD

8:45-9:30 mediastinaL tumOrs Jason C. Chang, MD

9:30-10:15 puLmOnary LymphOprOLiferative disOrders Ahmet Dogan, MD, PhD

10:15-10:45 Break

10:45-11:30 duCtaL adenOCarCinOma Of the panCreas Olca Basturk, MD

11:30-12:30 sOLid nOnduCtaL neOpLasms Of the panCreas David Klimstra, MD

12:30-1:45 LunCh

1:45-2:30 CystiC neOpLasms Of the panCreas Olca Basturk, MD

2:30-3:15 CytOLOgy Of panCreas neOpLasms Carlie Sigel, MD

3:15-3:45 Break

3:45-4:30 Neuroendocrine Neoplasms of the GI Tract – Conundrums and Caveats Laura Tang, MD

Wednesday, May 1, 2019

8:00-8:45 mOLeCuLar diagnOstiCs Of gi tumOrs Jaclyn Hechtman, MD

8:45-9:30 appendiCeaL epitheLiaL neOpLasms - Bewildering Between goBlet and Bucket of mucin Laura Tang, MD

9:30-10:00 Break

10:00-10:45 gastrOesOphageaL adenOCarCinOma and their preCursOr LesiOns - the Barrett’s anxiety Laura Tang, MD

10:45-11:30 gastriC pOLyps and Other epitheLiaL neOpLasms Michael Roehrl, MD

11:30-12:00 BiOmarker testing in upper gi tumOrs Michael Roehrl, MD

12:00-1:15 LunCh

1:15-2:00 seLeCted issues in COLOreCtaL tumOr pathOLOgy Jinru Shia, MD

2:00-3:00 gi tumOr diagnOsis: LessOns frOm priOr mistakes Jinru Shia, MD

3:00-3:30 Break

3:30-4:15 BiOpsy diagnOsis Of hepatiC tumOrs David Klimstra, MD

4:30-6:00 sLide seminar David Klimstra, MD

Thursday, May 2, 2019

8:00-8:45 duCtaL, intraduCtaL and CriBrifOrm, Oh my! the differentiaL diagnOsis Of Large gLand LesiOns Of the prOstate and its CLiniCaL impOrt Samson Fine, MD

8:45-9:30 essentiaL data eLements fOr prOstate CanCer repOrting in 2019 Samson Fine, MD

9:30-10:00 Break

10:00-10:45 risk stratifiCatiOn in prOstate CanCer; the rOLe Of COntempOrary tissue, urine and serum Based assays Anu Gopalan, MD

10:45-11:30 twO Cases tO rememBer: presentatiOn By the genitOurinary pathOLOgy suBspeCiaLty feLLOws

Drs. Liwei Jia and Sounak Gupta

11:30-12:15 mimiCs Of urOtheLiaL CarCinOma Victor Reuter, MD

12:15-1:30 LunCh

1:30-2:15 prOgnOstiC and prediCtive faCtOrs in urOtheLiaL CarCinOma; grading, staging and BeyOnd Hikmat Al-Ahmadie, MD

2:15-3:00 urOtheLiaL tumOrs Of the upper urinary traCt Hikmat Al-Ahmadie, MD

3:00-3:30 Break

3:30-4:15 a praCtiCaL apprOaCh tO the mOrphOLOgiCaL evaLuatiOn Of tumOrs Of the testis and its adnexa Satish Tickoo, MD

4:30-6:00 sLide seminar Anu Gopalan, MD

Friday, May 3, 2019

8:00-8:45 renaL neOpLasia: mOrphOLOgiC speCtrum and differentiaL diagnOsis. part 1 Satish Tickoo, MD

8:45-9:30 renaL neOpLasia: mOrphOLOgiC speCtrum and differentiaL diagnOsis. part 2 Yingbei Chen, MD

9:30-10:00 Break

10:00-10:45 germLine mutatiOns in urOgenitaL tumOrs; disease speCtrum and CLiniCaL impLiCatiOns Maria Carlo, MD

10:45-11:30 new and emerging variants Of renaL neOpLasms Yingbei Chen, MD

11:30-12:15 impLementatiOn Of whOLe sLide imaging in yOur LaBOratOry; ChaLLenges and OppOrtunities J. Sirintrapun, MD

12:15 COnCLusiOn

coursE faculty

COURSE DIRECTORS

Meera R. Hameed, MD Attending Pathologist Chief, Surgical Pathology Service

COURSE COORDINATOR

Sarah Virgo

ASSOCIATE COURSE DIRECTORS

Victor Reuter, MD Attending Pathologist Vice Chairman, Department of Pathology Director of Genitourinary Pathology

Jinru Shia, MD Attending Pathologist Director of Gastrointestinal Pathology

William D. Travis, MD Attending Pathologist Director of Thoracic Pathology

All sessions will be held in the Auditorium of the Rockefeller Research Laboratories, located at 430 East 67th Street between York and First Avenues on the Upper East Side of Manhattan.

MSKCC COURSE FACULTY

Hikmat Al-Ahmadie, MD Associate Attending Pathologist

Olca Basturk, MD Associate Attending Pathologist

Darren J. Buonocore, MD Assistant Attending Pathologist

Maria Carlo, MD Medical Oncologist, MSKCC

Jason C. Chang, MD Assistant Attending Pathologist

Yingbei Chen, MD, PhD Associate Attending Pathologist

Ahmet Dogan, MD, PhD Service Chief, Hematopathology

Samson W. Fine, MD Associate Attending Pathologist

Anuradha Gopalan, MBBS Associate Attending Pathologist

Sounak Gupta, MD Pathology Fellow

Meera Hameed, MD Service Chief, Surgical Pathology

Jaclyn F. Hechtman, MD Assistant Attending Pathologist

Liwei Jia, MD Pathology Fellow

David S. Klimstra, MD Chairman, Department of Pathology

Natasha Rekhtman, MD, PhD Associate Attending Pathologist

Victor Reuter, MD Vice Chairman, Department of Pathology

Michael H. Roehrl, MD, PhD Associate Attending Pathologist

Jennifer Sauter, MD Assistant Attending Pathologist

Jinru Shia, MD Attending Pathologist

Carlie S. Sigel, MD Assistant Attending Pathologist

Sahussapont J. Sirintrapun, MD Associate Attending Pathologist

Laura H. Tang, MD, PhD Attending Pathologist

Satish K. Tickoo, MD Attending Pathologist

William D. Travis, MD Attending Pathologist