Pathology of the gastrointestinal tract II (liver,...
Transcript of Pathology of the gastrointestinal tract II (liver,...
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Pathology of the
gastrointestinal tract II
(liver, pancreas).
X. practical training
3rd year Dentistry
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Congestion of the liver
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Congestion of the liver
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Congestion of the liver (hepar moschatum)
1 Portobilial spaces
2 Ways of congestion (congestion with
necrosis of hepatocytes)
Pseudolobulus from residues of 3 lobuli, in
centre is portobilium
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Congestion of the liver (hepar moschatum), detail
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1 Portobilium- dilatated branch of v. portae
2 Pseudolobulus from residues of 3 lobuli, in centre is
portobilium
3 Ways of congestion (congestion with necrosis of
hepatocytes)
4 Biliary duct
5 Branch of a. hepatica
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Liver steatosis
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Viral hepatitis
HAV RNA hepatovirus
HBV DNA hepadnavirus
HDV RNA defektní virus
non A non B (NANB)
HCV RNA flavi a pestivirus-like
HEV RNA kalicivirus
HFV RNA togavirus
HGV RNA flavivirus
others: herpesvirus, cytomegalovirus, paramyxovirus, ...
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Acute stage of
viral hepatitis
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Viral hepatitis
subacute fatal
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Chronic viral
hepatis
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Liver – chronic viral hepatis
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3 1 Portobiliar space with chronic inflammatory infiltrate
2 „piece-meal necroses“
3 Central part of lobulus with mixed steatosis
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Liver – chronic viral hepatis
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1 Chronic inflammatory
infiltrate in portobiliar space
2 Biliary duct
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Cirrhosis of the liver
etiology morphology
alcohol 60-70% mikronodular
CAH 10% makronodular
kryptogenic 10-15% mixed
biliáry primary
secondary
pigment haemochromatosis primary
secondary
Congenital metabolic disorders (tyrosinemia,galaktosemia ...)
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Cirrhosis of the liver
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Cirrhosis of the liver
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Cavernous haemangioma – liver
kopie
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Primary liver
carcinoma
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Hepatocellular carcinoma
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Hepatocellular carcinoma
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Hepatocellular carcinoma
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Cholangiocarcinoma of the liver
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Acute haemorrhagic necrosis of pancreas
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Cystic fibrosis of the pancreas
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Cystic fibrosis of the pancreas