7/28/2019 Paper 5 - Specific and Non-Specific Defenses v2

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Elizabeth D.

Specific and Non-Specific Resistance to Disease1

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7/28/2019 Paper 5 - Specific and Non-Specific Defenses v2

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Down

. Learned

2. Part of the 1st line of defense; a fluid that lubricates

& moistens the cavity surface; it traps microbes and

foreign substances; it contains microbial propertiesto filter, moisturize, and warms air

. Coordinate activity of the immune response;

cytokines are secreted to stimulate the non-specificimmune response to continue, strengthen and boost

appropriate specific responses (2 words)

5. Are mediated by cells not by antibodies; there aredifferent types with different antigens on their

surfaces and have different roles in the immune

response; cells mature in the thymus (2 words)7. Occurs during the activation of T cells because they

require two signals to become fully activated - anantigen-specific and antigen nonspecific

8. Remembers the previous antigen so a secondencounter prompts an even more rapid and vigorous

response; long-term-stable cells that can

differentiate into plasma cells (2 words)0. A defense mechanism that uses at least 30 proteins

in the blood that helps antibodies kill the invaders

(2 words)1. An essential part in the defense against microbes;

are involved early in nonspecific defense responses

(2 words)2. Defenses, that are not specific to individualpathogens (2 words)

3. Produce antibodies; that is, they do not mature in

the thymus

14. Highly focused identification of a foreign molec

then seek it out all over the body to attack on a

particular antigen (2 words)

15. Deal with antigens that have gotten through theinitial defenses and still remain a threat to the

infected organism; involves chemical and cellula

defenses (4 words)16. Usually has direct contact with the external

environment (4 words)

18. Immune cells that never forget (2 words)20. Genetic

21. 2nd Responders; they are very large phagocytes

are slow and powerful; they reach out & grabbacterium and pull it into the vesicle; are a vital

between the non-specific & specific defenses

Across

1. These are usually proteins, usually associated w

the surface of a foreign object, sets off a defense

reaction; Epitopes are part of these4. First recognize that other body cells are infected

then kills those cells therefore kills cell AND the

infection (3 words)6. Cells that can IMMEDIATELY produce (and

secrete) antibody molecules (2 words)

9. All mucous secreting cells lining all openings inthe body (2 words)14. A biological barrier protecting the internal

environment

17. Destroys its own cells that have been infected byviruses, or that have become cancerous (3 words

19. This is what you are born with (2 words)

22. They must recognize (2 words)

A. 1st Line of Defense

B. 2nd Line of Defense

C. Acquired

D. Antigen Dependent

E. AntigenIndependent

. Antigens

G. B-Lymphocytes

H. Complement

System

I. Co-Stimulation

J. Cytotoxic Killer TsK. Helper T-Cells

L. Innate

M. Macrophages

N. Memory B-Cells

O. Mucous

P. Mucous Epithelium

Q. Non SpecificDefense

R. Phagocytic Cells

S. Plasma B-Cells

T. Skin

U. Specific Resist

V. T-Cell Recepto

W. T-Lymphocyte

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Specific and Non-Specific Resistance to DiseaseAnswer Key

1A N T I G E N S C

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M Q U

U

3H

4C Y T O T O X I C K I L L E R T S 5T O R L -U E 6P L A S M A B - C E L L SS D E Y

R M 7

C 8M 9M U 10C O U S E P I T H E L I U M P O E O -

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P H 12

N - M 13B M 14S K I N C 152 H O 0 S O - P P E 161 N A C 17

N A T U R A L K I L L E R C E L L S S D G Y S I Y Y E C L T L O T P M B M M I S L I C E E U - P E F 18M I N Y S C L C H

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A N T I G E N

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I N D E P E N D E N T I A E O T C N M E O I F T L C S R 21M N O O F C I I L Y Y E A A R F D C C O S T S S C T Y D E E D N E T I R E T E F L E S E S O - F E L F M T P C E N S E A H E N C N N A L C E C C G L E E 22T - C E L L R E C E P T O R S

S