EMPOWERING RESULTS

P GC-HRTEGASUS® +

LECO P GC HRT’s -EGASUS+

The ultimate analytical instrument forincreased confidence in the

identification of components in yourmost complex samples.

For complete patent information, see specification sheet 209-212-001.

1 ppm accuracy and 50,000resolution at 200 spectra/secondallows you to win the fightagainst coelution with a highdegree of confidence

Build Your Confidence FurtherIndustry Advantages� Mass Resolution up to 50,000 gives you

the capability to distinguish compounds incoeluting peaks

� 1 ppm mass accuracy reduces molecularpossibilities by a factor of 3 versus industrystandards

� Shorten your identification time with theindustry’s best deconvolution forboth EI and CI data

Driven by Fundamental Technologies

�

® ®

sFolded Flight Path (FFP ) enables highresolution analysis with electable 20 or40 meter long flight paths

�

® ®High Resolution Deconvolution (HRD )uses a statistical approach to deconvoluteanalytes to the limits of mathematics

� ewN Encoded Frequent Pushing (EFP )allows increased sensitivity

® ®

�

®KADAS , a novel data acquisition system, isbased on ion statistics and ensures a highlevel of TOF data quality

FFP®

KADAS®KADAS®

MassAccuracy

MassAccuracy

HighResolution

HighResolution

� Mass defect plots allow you to quicklyfocus on compounds of interest

� Automated tuning and instrument setup

� Standard Electron Impact (HR-EI) andoptional Chemical Ionization (HR-CI)sources are easily exchangeable

� Unparalleled sensitivity in a highresolution GC-TOFMS system

Leading to Benefits� compounds viaIdentify library searches,

combined with accurate masses onmolecular and fragment ions

� Create and use accurate mass spectraldatabases to enhance the quality ofyour hits

� Monitor, regulate, use, and setupinstrument with automated softwaretools

� 2Standard He and H carrier gas support

HRD®HRD®

EFP

X10

EFP®

10

Patented Folded Flight Path

For more information on EFP refer to technical brief 209-066-018.

PEGASUS GC HRT Hardware- +

KADAS – Patented ion statistics-baseddata acquisition system, whichdramatically reduces noise, ensuresmass accuracy, and reduces file size.

New Encoded FrequentPushing – Patentedmethod of pulsing theOrthogonal Acceleratormultiple times toincrease duty cycle (x10)

Transfer ion optics to maximize transmissioninto the unique mass analyzer.

Pneumatic gate valve to quickly performfront-end maintenance without venting themass analyzer.

FFP provides high order TOF focusing whichdelivers high resolution sensitivity andaccommodates for typical TOF ion beamdispersion.

Novel Gain Optimization algorithm maximizessensitivity and dynamic range.

Dual Orthogonal Acceleration focuses more ionsinto the analyzer.

HR-EI orHR-CI Sources

Statistical models are used tocharacterize the probability of asingle ion event and acquire onlymeaningful analytical data.is also designed to enhance spectralacquisition rates.

KADAS

Gridless Mirror

Gridless Mirror

Periodic Ion Lenses

Ion Source

Detector

PEGASUS GC-HRT Software+

Increase confidence in your identification challenges with intuitive ChromaTOF brand software. In addition tostandard instrument support, new and revamped Windows ribbon-style menu system isdesigned for superior mass accuracy from high resolution mass spectrometry. Tools and workflows available inour software will increase confidence in your ability to identify components.

®

ChromaTOF's®

Chromatogram

Spectral Match

DeconvolutionSpectrum

Accuracies of Fragment IonsDeconvolution Summary

UnknownCompoundUnknown

Compound

HR-EI and/orHR-CI

Deconvolution(Peak True)

HR-EI and/orHR-CI

Deconvolution(Peak True)

Con�denceGrows

Con�denceGrows

Molecular Ion (HR-CI)Retention Time

Molecular Ion (HR-CI)Retention Time

TentativeAssignment

TentativeAssignment

Spectral MatchTop Hit

Spectral MatchTop Hit

Identi�cation

Standards &Deconvoluted

Fragments

Standards &Deconvoluted

Fragments

1

1

2

3

3 4

4

2

High Resolution Deconvolution HRD( )

In cases where ambiguity exists, Ultra High Resolution mode and will pull apart highly isobaric ions. In theexample below, the required mass resolution is greater than 40,000.

HRD

What else is in your sample?HRD with 25,000 resolution deconvolutes and identifies important analytes in complex matrices.

0

40

60

80

100

20

R = 25,000

R = 50,000

cyanazine240.08847[C H ClN ]9 13 6

•+

metolachlor240.09637[C H Cl ]13 17 NO +

240.09515>

240.09644>

240.08849>

0.083 ppm

0.30 ppm

240.06 240.08 240.1 240.12M/Z

0

40

60

80

100

20

Rela

tive

Abundance

A

-5.1 ppm

NN N

CI

O

OCH3

NH

N

CI

N

HN

ChromatogramUHR Mode

632 634 636 638 640 642 644

XIC(240.0885±0.0005)

XIC(240.0964±0.0005)

cyanazi

ne

meto

lach

lorB

A

B

Lindane, Library Similarity: 842

Neophytadiene, Library Similarity: 886

1000

1000

75

.02

30

3

11

0.9

99

75

14

5.9

68

47

21

8.9

11

09

180.93739

179.17953

10

9.1

01

26

12

3.1

16

87

68.0621095.08553

251.88271

278.29674

0.43 ppm

0.35 ppm

0.55 ppm

0.23 ppm

-0.24 ppm

-0.51 ppm

800

800

600

600

400

400

200

200

0

0M/Z 100 150 200 250 300

CI

CI

CI

CI

CI

CI

TIC(Tobacco Matrix)

HRDR=25,000

Lindane

650 652 654 656 658 660Time (s)

XIC(57.0700±0.0005) XIC(68.0621±0.0005)XIC(82.0777±0.0005) XIC(95.0855±0.0005)XIC(123.1169±0.0005) XIC(108.9607±0.0005)XIC(180.9374±0.0005) XIC(182.9345±0.0005)XIC(216.9142±0.0005) XIC(218.9111±0.0005)Constant(0.050000)*TIC

Neophyt

adie

ne

HRD®HRD®

150 200 250 300 350 400 450 500 550 600

0.0

0.2

0.4

0.6

0.8

m/z

2200 2300 2400 2500 2600 2700 2800Time (s)

XIC(446.8158±0.0005) XIC(448.8142±0.0005)XIC(525.7344±0.0005) XIC(527.7324±0.0005)XIC(529.7308±0.0005)

Sca

led M

ass

Defe

ct

Find and quantify an unlimited number of analytes—in every run, every time. No need for additionaltargeted analyses.

Mass Defect Plot for Discovery of Unknown Compounds

Enhanced Sensitivity

Easily identify compounds with chemically scaled mass defect plots. From Kendrick to halogen,you can choose your mass defect scale.

Pegasus GC-HRT+

Detection Limit

IDL < 100 fg 8 replicate injectionsof 100 fg OFN

m/z 271.987 ± 0.5 mDa

New Option! Spectral Analysis Tools – get the most out of your data!

Pegasus GC-HRT+

Quantitative Dynamic Range0.10 pg–10,000 pg OFN

2000 4000 6000 8000 10000 12000 14000

Concentration

100pg

1,000pg

5,000pg

10,000pg

r = 0.99983

5 Orders

2 4 6 8 10 12Concentration

0.1pg

1pg

5pg

10pg

LECO Corporation3000 Lakeview Avenue | St. Joseph, 49085 | 800-292-6141 | Phone: 269-985-5496MI

info@leco.com | www.leco.com | -9001:2015 Q-994 | LECO is a registered trademark of LECO Corporation.ISO

EMPOWERING RESULTS

Form No. 209-212 4 © 2019 CorporationLECO6/19-REV

Identify More With Confidence

Do you know what is in your sample With our solutions, you’ll have allthe advantages you need to see the complete picture

?

Unknowns don't stand a chance when you have the leader in inyour corner. products deliver the separation, accuracy, resolvingpower, deconvolution, and speed to characterize the most complexmatrices.

GC-MSLECO

PEGASUS GC-HRT+PEGASUS GC-HRT+

Productivity | ReproducibilityProductivity | Reproducibility

Deconvolution | Sensitivity

Accurate Mass | Structural Interpretation

Life Sciences and Chemical Analysis SolutionsEvery day around the world, instruments continuously perform analyses for today's most complex applications.Whether you are analyzing samples in the food, flavor/fragrance, petroleum, environmental, forensics, or life science(metabolomics) industries, we have an instrument configuration to meet your needs.

LECO

GC GCx

� Supports Flame Ionization Detector

� Make your GCxGC analysis routine with single channel detectors

� Classification software feature simplifies component identification and results summary

� Compatible with other single channel detectors

� StayClean ion source eliminates the need for source cleaning

PEGASUS BT 4D GCxGC-TOFMS� Enhanced sensitivity by coupling our benchtop Pegasus BT with our high

performance GCxGC thermal modulation system for analyzing the mostcomplex samples

� Cost-effective FLUX™ Flow modulation system is an excellent option for thoselooking for added capability over one dimensional GC

� Unique and powerful brand software simplifies quantitation andanalyte identification with features such as NonTarget Deconvolution (NTD),Target Analyte Find, library searches, and more

ChromaTOF

PEGASUS BT GC-TOFMS

� Robust, extremely low maintenance ion source

� Full-mass range sensititvity and speed with unparalleled deconvolution capabilities allow you tosee more in standard analyses

� ChromaTOFPowerful Windows-based brand software simplifies componentidentification—providing a significant increase in efficiency and productivity

� peak findingQC

Key features include automated , chromatogram locking, reverse-library searchmode, and data-dependent user-defined method development

A Commitment to Quality and ServiceLECO

ISO CE

instruments are noted for superior precision, speed, and ease-of-use. We are an international company with over25 subsidiaries worldwide. Our global network of sales/support is dedicated to customer service and satisfaction, and ourcommitment to quality is further underscored with -9001:2015 certification. We conform to quality and safetyspecifications, fully testing our instruments at our on-site Compliance Testing Center.

Technical Research Center Global Support CenterRobert J Warren Customer Experience Center

LECO, Pegasus, FLUX, ChromaTOF, Folded Flight Path, FFP, High Resolution Deconvolution, HRD, KADAS,Encoded Frequent Pushing, and EFP are registered trademarks of LECO Corporation.Microsoft, Windows are registered trademarks of Microsoft Corporation.