Oxytocin and Resilience. Oxytocin The “Love Hormone” ◦ Trust ◦ Positive feelings ◦...
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Oxytocin and Oxytocin and Resilience Resilience
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Transcript of Oxytocin and Resilience. Oxytocin The “Love Hormone” ◦ Trust ◦ Positive feelings ◦...
OxytocinOxytocinThe “Love Hormone”
◦Trust◦Positive feelings◦Anxiolytic◦Sex and pair bonding◦Empathy
Produced: HypothalamusReleased: Posterior PituitaryGq – PLC/IP3 pathway
Different PolymorphismsDifferent PolymorphismsChen 2011
◦ Rs53576 GG GA AA
Thompson 2011◦ Rs2254298
GG GA
Thompson 11Thompson 11
Mother with depression?
Rs2254298?
Hi / Low adversity + / - polymorphisim
Environment x Genetics
Receptor PolymorphismReceptor PolymorphismRs53576
◦Adenosine (A) instead of a Guanine (G)
◦Opposite effect of adding Oxytocin
◦Non-coding intron mutation! “the genetic variant investigated in this
study in likely a marker for still-unidentified functional variants of the gene”