Overview of the ACE study - Delaware Courts · Overview of the Adverse Childhood Experiences (ACE)...

31
Overview of the Adverse Childhood Experiences (ACE) Study Robert F. Anda, MD, MS Co-Principal Investigator www.acestudy.org

Transcript of Overview of the ACE study - Delaware Courts · Overview of the Adverse Childhood Experiences (ACE)...

Ove

rvie

w o

f the

Adv

erse

Chi

ldho

od

Exp

erie

nces

(A

CE

) S

tudy

Rob

ert F

. And

a, M

D, M

SC

o-P

rinci

pal I

nves

tigat

or

ww

w.a

cest

udy.

org

Ado

ptio

n of

H

ealth

-ris

k B

ehav

iors

Soc

ial,

Em

otio

nal,

&

Cog

nitiv

e Im

pairm

ent

Ear

lyD

eath

Adv

erse

Chi

ldho

od E

xper

ienc

es

Dea

th

Dis

ease

, Dis

abili

tyan

d S

ocia

l Pro

blem

s

Con

cept

ion

Sci

entif

icga

ps

The

Adv

erse

Chi

ldho

od E

xper

ienc

es (

AC

E)

Stu

dy

Exa

min

es th

e he

alth

and

soc

ial e

ffect

s of

AC

Es

thro

ugho

ut th

e lif

espa

n am

ong

17,4

21 m

embe

rsof

the

Kai

ser

Hea

lth P

lan

in S

an D

iego

Cou

nty

Wha

t do

we

mea

n by

Adv

erse

Chi

ldho

od E

xper

ienc

es?

-chi

ldho

od a

buse

and

neg

lect

-gro

win

g up

with

dom

estic

vio

lenc

e, s

ubst

ance

abus

e or

men

tal i

llnes

s in

the

hom

e, p

aren

tal

disc

ord,

crim

e

Follow

-up

AC

E S

tudy D

esig

n

Surv

ey W

ave I

M

ort

ality

(N=

9,5

08)

National D

eath

Index

Morb

idity

Hospital D

ischarg

e

Outp

atient

Vis

its

Surv

ey W

ave II

Em

erg

ency r

oom

(N

=8,6

67)

vis

its

Pharm

acy

Utilization

All

medic

al evalu

ations

abstr

acte

d f

rom

both

waves

(N =

17,4

21)

Adv

erse

Chi

ldho

od E

xper

ienc

es A

re C

omm

on

Sub

stan

ce a

buse

27%

Par

enta

l sep

/div

orce

23%

Men

tal i

llnes

s17

%B

atte

red

mot

her

13%

Crim

inal

beh

avio

r

6

%

Hou

seho

ld d

ysfu

nctio

n:

Abu

se:

Psy

chol

ogic

al

11%

Phy

sica

l28

%S

exua

l21

%

Neg

lect

:E

mot

iona

l

1

5%P

hysi

cal

1

0%

Adv

erse

Chi

ldho

od E

xper

ienc

es R

arel

y O

ccur

in Is

olat

ion…

The

y co

me

in

grou

ps.

Dom

estic

Vio

lenc

ean

d th

e R

isk

of O

ther

AC

Es

...

Pre

vale

nce o

f C

hildhood A

buse b

y F

requency o

f W

itnessin

g D

om

estic V

iole

nce

Pre

vale

nce o

f C

hildhood A

buse b

y F

requency o

f W

itnessin

g D

om

estic V

iole

nce

Childhood A

buse

Em

otional

Physic

al

Sexual

0

20

40

60

80

100

Never

Once,T

wic

eSom

etim

es

Oft

en

Very

oft

en

Fre

quency o

f w

itnessin

g

dom

estic v

iole

nce

Percent (%)

AC

Es

tend

to c

ome

in g

roup

s…

Add

ition

al A

CE

s (%

)1

23

4>5

If y

ou

had

:A

bat

tere

d m

othe

r95

8264

4852

Adv

erse

Chi

ldho

od E

xper

ienc

es S

core

Com

plex

Tra

uma-

-Tra

uma

“Dos

e”N

umbe

r of

indi

vidu

al ty

pes

of a

dver

se

child

hood

exp

erie

nces

wer

e su

mm

ed…

AC

E s

core

Pre

vale

nce

033

%1

26%

216

%3

10%

4 or

mor

e16

%

AC

E S

core

and

Tee

n S

exua

l Beh

avio

rs

051015202530354045

Percent With Health Problem (%)

01

23

4 o

r m

ore

AC

E S

core

Inte

rcou

rse

by

Age

15

Tee

n P

regn

ancy

Tee

n P

ater

nity

The

AC

E S

core

and

the

Pre

vale

nce

of

Sev

ere

Obe

sity

(B

MI >

35)

02468101214

01

23

>=4

AC

E S

core

Percent obese (%)

AC

Es a

nd M

enta

l H

ealth…

The

AC

E S

core

and

the

Pre

vale

nce

of

Atte

mpt

ed S

uici

de

05101520

01

23

>=4

AC

E S

core

Percent atempted (%)

The

AC

E S

core

and

a L

ifetim

e H

isto

ry o

f D

epre

ssio

n

010203040506070

01

23

>=4

Wom

enM

en

AC

E S

core

Percent depressed (%)

AC

Es a

nd V

iole

nt

Vic

tim

ization a

s a

n A

dult…

AC

E S

core

and

the

Ris

k of

Bei

ng a

Vic

tim o

f Dom

estic

Vio

lenc

e

051015W

om

en

Men

0 1 2 3 4 >

50 1 2 3 4 >

5

Risk of Victimization (%)

AC

E S

core

Eve

r ad

dict

edto

dru

gs

AC

E S

core

and

Dru

g A

buse

02468101214

Percent With Health Problem (%)

01

23

4>

=5

AC

E S

core

Eve

r ha

d a

drug

pro

blem

Eve

r in

ject

eddr

ugs

AC

E S

core

and

HIV

Ris

ks

02468

10

12

14

16

18

20

Percent With Health Problem (%)

01

23

4 o

r m

ore

AC

E S

core

Eve

r In

ject

edD

rugs

Had

50

or M

ore

Inte

rcou

rse

Par

tner

sE

ver

Had

an

ST

D

02468101214161820

Percent With Health Problem (%)

01

23

4 or

mor

e

AC

E S

core

Ear

ly s

mok

ing

initi

atio

nC

urre

nt s

mok

ing

CO

PD

AC

Es,

Sm

okin

g, a

nd L

ung

Dis

ease

The

AC

E S

core

and

the

Pre

vale

nce

Isch

emic

H

eart

Dis

ease

0123456

01

23

>=4

AC

E S

core

Percent (%)

One P

ers

pective o

n t

he D

irect

Health

Care

Costs

of

AC

Es:

The B

urd

en o

f Pre

scription D

rug U

se

Pre

scription D

rugs in t

he U

nited S

tate

s (2003)

-nearly $

180 b

illion s

pent

-11%

of

tota

l national health e

xpenditure

s

-more

than f

our

tim

es t

he a

mount

spent

in 1

990

AC

E S

core

and

Rat

es o

f Ant

idep

ress

ant

Pre

scrip

tions

0

10

20

30

40

50

60

70

80

90

100

AC

E S

core

0

1

2

3

4

>=5

Prescription rate

(per 100 person-years)

AC

E S

core

and R

ate

s o

f P

rescribed

Antidepre

ssant

Medic

ations b

y A

ge,

1997-2

004

1Rel

ativ

e ra

tes

are

adju

sted

for

age

, sex

, rac

e/et

hnic

ity, a

nd e

duca

tion.

Adu

lts w

ith a

n A

CE

Sco

re o

f 0

are

the

refe

rent

.

020406080100

120

140

01

23

45+

01

23

45+

01

23

45+

Rate per 100 P-Y

AC

E S

core

45-6

4 y

rs

AC

E S

core

18-4

4 y

rs

AC

E S

core

65-8

9 y

rs

Adv

erse

Chi

ldho

od E

xper

ienc

esas

a C

linic

al a

nd P

ublic

Hea

lth Is

sue

AC

Es:

-ar

e en

dem

ic-

high

ly in

terr

elat

ed-

have

a c

umul

ativ

e st

ress

or e

ffect

-ef

fect

s ar

e bi

olog

ical

ly p

laus

ible

Adv

erse

Chi

ldho

od E

xper

ienc

esA

s a

Nat

iona

l Hea

lth Is

sue

AC

Es

have

a s

tron

g in

fluen

ce o

n:-a

dole

scen

t hea

lth-r

epro

duct

ive

heal

th-s

mok

ing

-alc

ohol

abu

se-il

licit

drug

abu

se-s

exua

l beh

avio

r-m

enta

l hea

lth-

risk

of r

evic

timiz

atio

n-s

tabi

lity

of r

elat

ions

hips

, hom

eles

snes

s-p

erfo

rman

ce in

the

wor

kfor

ce

Adv

erse

Chi

ldho

od E

xper

ienc

esA

s a

Nat

iona

l Hea

lth Is

sue

AC

Es

incr

ease

the

risk

of:

-Hea

rt d

isea

se-

Chr

onic

Lun

g di

seas

e-

Live

r di

seas

e-

Sui

cide

-In

jurie

s-H

IV a

nd S

TD

s-

and

othe

r ris

ks fo

r th

e le

adin

gca

uses

of d

eath

The A

dvers

e C

hildhood E

xperiences

(AC

E) Stu

dy

Sum

mary

of

Fin

din

gs:

-Advers

e C

hildhood E

xperiences (

AC

Es)

are

very

com

mon

-AC

Es a

re s

trong p

redic

tors

of

health r

isks a

nd

dis

ease f

rom

adole

scence t

o a

dulthood

-This

com

bin

ation o

f findin

gs m

akes A

CEs o

ne

of

the leadin

g, if n

ot

the leadin

gdete

rmin

ant

of

the h

ealth a

nd s

ocia

l w

ell-b

ein

g o

f our

nation

Brid

ging

The

Cha

sm

Chi

ld

heal

thas

it

stan

dsto

day

Chi

ld

heal

thas

itco

uld

be

Bre

akth

roug

hsin

mol

ecul

ar g

enet

ics

and

biol

ogy

:M

enta

l illn

ess

Sub

stan

ce a

buse

Vio

lenc

e

Impr

oved

rec

ogni

tion

and

trea

tmen

t of

:M

enta

l illn

ess

Sub

stan

ce a

buse

Dom

estic

vio

lenc

eC

hild

abu

se

Mas

s ed

ucat

ion

abou

t chi

ld

deve

lopm

ent &

pare

ntin

g:

Med

iaS

choo

ls

Doc

umen

ting

the

soci

etal

bur

den

ofch

ild h

ealth

as

it st

ands

toda

y

New

dire

ctio

nsin

pre

vent

ion

and

trea

tmen

t

Brid

ging

The

Cha

sm

Chi

ld

heal

thas

it

stan

dsto

day

Chi

ld

heal

thas

itco

uld

be

Invo

lvin

g th

ose

who

don

’t ye

t rea

lize

that

they

are

wor

king

on

issu

es th

at

repr

esen

t the

“do

wns

trea

m”

wre

ckag

eof

chi

ld a

buse

and

neg

lect

--an

d ot

her

adve

rse

child

hood

exp

erie

nces

--in

the

effo

rt to

brid

ge th

e ch

asm

.

Rou

tine

scre

enin

g fo

r tr

aum

a is

nee

ded