Ovarian reserve New insights for clinical...
Transcript of Ovarian reserve New insights for clinical...
ESHRE Campus 2008Modena Italy 18 & 19 April 2008
Workshop organised by the Special Interest Group‘Reproductive Endocrinology’
Ovarian reserveNew insights for clinical management
ESHRE Campus workshop
Ovarian reserveNew insights for clinical management
Modena Italy 18 & 19 April 2008
Courseobjectives
COuRSE dESCRIptIOnIn Reproductive Medicine there are several topics that impact greatly on patients and are of great concern
for clinicians and scientists alike. Ovarian reserve and ovarian response to gonadotropin stimulation
continue to be pressing examples. The main topics of the course will be the following:
Definition of ovarian reserve, the clinical assessment of ovarian reserve, the role of Anti-Mullerian Hormone
in reproductive medicine, the clinical relevance of ovarian reserve assessment, and therapeutic options
for women with reduced ovarian reserve.
The SIG Reproductive Endocrinology is offering a two-day course aimed at clinicians and researchers
with an interest in the ovarian gonadal function and its manipulation. The course will attempt to analyse
the current diagnostic possibilities in the evaluation of ovarian reserve. The course will also describe the
current status of therapeutical approach to women with diminished ovarian reserve.
At the conclusion of this course, the participants should be able to:
• understand the physiology of ovarian function
• understand the factors influencing the ovarian reserve
• understand the role of AMH in regulating folliculogenesis and its diagnostic utility
• apply the diagnostic procedure in the evaluation of ovarian reserve
• know the different therapeutical approaches to women with reduced ovarian reserve
Gynaecologists, reproductive endocrinologists, biologists and all those with interest in reproductive medicinetarget audience
Scientificorganisers
Scientificcommittee
Faculty
A. Volpe (Italy)
N. Macklon (The Netherlands)
A. La Marca (Italy)
S. Giulini (Italy)
F.J. Broekmans (The Netherlands)
P.G. Crosignani (Italy)
A. De Pol (Italy)
P. Devroey (Belgium)
J. Dor (Israel)
R. Fanchin (France)
B. Fauser (The Netherlands)
R. Felberbaum (Germany)
A.R. Genazzani (Italy)
L. Gianaroli (Italy)
S. Giulini (Italy)
A. Gougeon (France)
V. Jasonni V (Italy)
N. Josso (France)
A. La Marca (Italy)
C.B. Lambalk (The Netherlands)
N. Macklon (The Netherlands)
G.B. Melis (Italy)FACuLtY & ORGAnISAtIOn
Faculty
Local organising secretariat
Organising secretariat
S. Muttukrishna (United Kingdom)
C. Nappi (Italy)
F. Petraglia (Italy)
J. Tapanainen (Finland)
D. Toniolo (Italy)
A. Veiga (Spain)
J. Visser (The Netherlands)
A. Volpe A (Italy)
MKT Consulting
Via Cassia 1110
00189 Rome • Italy
Tel: +39 06 397 46 189
Fax: +39 06 393 72 581
Email: [email protected]
ESHRE Central Office
Meerstraat 60
1852 Grimbergen • Belgium
Tel: +32 2 269 09 69
Fax: +32 2 269 56 00
E-mail: [email protected]
Modena
GEnERAL InFORMAtIOnAula Magna
Centro Servizi – Facoltà di Medicina e Chirurgia
Policlinico di Modena
Via del Pozzo, 71
41100 Modena
Italy
Modena is located in Emilia-Romagna, a north-central region of Italy stretching over a fertile
plane and flanking the Apennine Mountains. With its 200,000 inhabitants, it is both tranquil
and lively, a place where modernity and tradition meet and engage comfortably with one
another.
You can explore Modena by having a ‘passeggiata’ under the porticos overarching its sidewalks.
The cobblestone streets of the historic center and the buildings’ amber shades give you the
opportunity to relive the medieval town still filled by the echoes of the court of the Estense
family.
Modena is home to the twelfth-century Romanesque Cathedral declared by Unesco to be among
the five hundred masterpieces of the world; the impressive rooms of the municipal palace;
Venue
the imposing Palazzo Ducale; the collective beauty of numerous churches. The city’s artistic and historic
treasures coexist in harmony with bookstores, boutiques where artists and artisans sell their goods, traditional
markets, bars where you can sit and drink an aperitivo, as well as Modena’s renowned restaurants and the
less formal trattorias.
Finally, its central geographic location allows you to reach the major cities as well as the smaller, lesser-known
towns of Italy quite easily.
Modena is located in quite a strategic position: it is very close and well connected with some well known
cities like Milan, Venice, Verona, Florence, Bologna and other cities, maybe not as well know, but never the
less beautiful and full of interesting things to see. Furthermore, it is possible to make beautiful excursions
to the Apennine, the charming mountains on the border of Emilia-Romagna and Tuscany, or easily reach
the Adriatic Sea in the east (Rimini, Riccione etc, famous for the most entertaining night life of Italy) or
the Ligurian Sea and the Tyrrhenian Sea in the west (characterized by beautiful villages such as Cinque
Terre or great beaches like the one of Versilia).
For info on Modena see www.terredimodena.it/english/info.asp
How to reachModena?
GEnERAL InFORMAtIOnIf you arrive in Italy by plane the nearest airport to Modena is the airport Marconi of Bologna
(about 30 km from Modena). From Bologna you can take a bus, train or taxi to Modena.
There is a direct bus from the Bologna airport to Modena - price of the one-way ticket: € 10.
The bus leaves every 2 hours from 6:15 to 22:30. The bus stop is at the exit of the airport,
international arrivals, at the bus stop ATCM (see www.atcm.mo.it/aerobus.asp)
There is also a bus from the airport to the train station of Bologna from where it is possible to take a
train to Modena - price of the one-way ticket: about € 5 without the supplementary charges
(see www.trenitalia.com).
The taxi is probably the easiest way to arrive in Modena (about € 60).
The other Italian airports from which it is easy to reach Modena are:
Milan Linate - 30 minutes by bus to the central station of Milan + 2 hours by train to Modena.
Milan Malpensa - 40 minutes by train to the central station of Milan + 2 hours by train to Modena.
Bus
train
taxi
How to reachthe meeting venue?
Take the bus n.7 from Modena Railway Station. In 10-15 minutes you will reach the University
Hospital ‘Policlinico di Modena’. The Aula Magna is in the Facoltà di Medicina e Chirugia building.
From the Railway station you will reach the congress venue in 10 minutes
MKT Consulting
Via Cassia 1110
00189 Roma
Italy
Tel: +39 06 397 46 189
Fax: +39 06 393 72 581
Email: [email protected]
By bus
By taxi
Hotelaccommodation
pROGRAMME - 18 ApRIL 200808.30 - 09.20 Registration
09.20 - 09.35 Welcome and opening of the meeting A. Volpe (Italy), N. Macklon (The Netherlands)
Definition of ovarian reserve
Chair: A. De Pol (Italy), V. Jasonni (Italy)
09.35 - 10.00 Fertility and reproductive ageing P.G. Crosignani (Italy)10.00 - 10.25 Ovarian reserve: quantity or quality J. Tapanainen (Finland)10.25 - 10.50 Genetic determinants of ovarian reserve D. Toniolo (Italy)10.50 - 11.15 Neo-oogenesis: myth or reality? A. Gougeon (France)11.15 - 11.45 Coffee break
Assessment of ovarian reserve
Chair: N. Macklon (The Netherlands), G.B. Melis (Italy)
11.45 - 12.10 Ultrasound markers of ovarian reserve F. Broekmans (The Netherlands)12.10 - 12.35 Hormonal markers of ovarian reserve S. Muttukrishna (UK)12.35 - 13.00 Efforts to improve the reliability of ovarian reserve markers R. Fanchin (France)13.00 - 14.20 Lunch
Morning
Afternoon Antimullerian hormone: a clinical update
Chair: P. Devroey (Belgium), R. Genazzani (Italy)
14.20 - 14.45 The physiological role of AMH N. Josso (France)14.45 - 15.10 Circulating AMH from fetus to adulthood J. Visser (The Netherlands)15.10 - 15.35 AMH as a marker of ovarian dysfunction B. Fauser (The Netherlands)15.35 - 16.00 AMH: Clinical relevance in ART A. La Marca (Italy)16.00 - 16.30 Coffee break
Round table - ‘AMH: what do we still need to know?’
Chair: B Fauser (The Netherlands)
16.30 - 18.30
Discussants: F. Broekmans, P. Devroey, R. Fanchin, A. Gougeon, N. Josso, A. La Marca,C. Lambalk, S. Muttukrishna, J. Tapanainen, J. Visser
Aim: To formulate future research needs.
Topics include: Assay standards, function in PCOS, AMH receptor SNPs
Morning
pROGRAMME - 19 ApRIL 2008Clinical aspects
Chair: C. Nappi (Italy), F. Petraglia (Italy)
09.00 - 09.25 Ovarian ageing and twinning C. Lambalk (The Netherlands)09.25 - 09.50 The ART and pregnancy outcome in patients with
diminished ovarian reserve L. Gianaroli (Italy)09.50 - 10.15 Cost-effectiveness of infertility treatment in ageing women P. Devroey (Belgium)10.15 - 10.40 Preservation of fertility in women at risk for depletion of ovarian reserve J. Dor (Israel)10.40 - 11.10 Coffee break
Options for women with diminished ovarian reserve
Chair: B. Fauser (The Netherlands), A. Volpe (Italy)
11.10 - 11.35 GnRH analogs in poor responders S. Giulini (Italy)11.35 - 12.00 Gonadotropin stimulation regimens N. Macklon (The Netherlands)12.00 - 12.25 Adjuvant therapies R. Felberbaum (Germany)12.25 - 12.50 Making gametes and helping embryos A.Veiga (Spain)12.50 - … Closing remarks A. Volpe (Italy), N. Macklon (The Netherlands)
SOCIAL EVEntSWorkshop dinner at Villa Cesi - 18 April
The dinner will be held in an ancient villa in the Modena countryside. During the dinner
a musical entertainment will be provided.
The dinner is optional and a fee of 100 Euro is charged.
Social event at the Galleria Ferrari - 19 April
On Saturday 19, at the end of the meeting, you will leave Modena and reach Maranello
(20 minutes by bus) to have a lunch in the restaurant “il Cavallino” and to have a visit
in the galleria Ferrari (www.ferrariworld.com). We will come back in Modena at 6 p.m.
The social event is optional and a fee of 70 euro is charged.
18 April
19 April
REGIStRAtIOnSFor availability of places, please check first with the ESHRE Central Office. The following fees apply:
1. Members of ESHRE = 150 Euro
2. Non-members of ESHRE = 200 Euro
3. Student member of ESHRE = 70 Euro
4. Student non-member of ESHRE* = 100 Euro
5. Accompanying person = 70 Euro
‘Student’ applies to undergraduate, graduate and medical students, residents and post-doctoral research trainees. A letter
from the Head of the department proving the participant’s student status must accompany each student registration.
• Attendance to all sessions
• Symposium syllabus
• Lunches
• Coffee breaks
• Certificate of attendance
• Lunches
• Coffee breaks
All cancellations should be made in writing. An administrative fee of 25 Euro will be charged
for all cancellations. Cancellations received after 15 March 2008 will not be refunded.
Registrationfees 1 - 4 include
Cancellationpolicy
Registrationfees 5 includes
*
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