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DRUG STUDY

DRUGORDER(Generic

name,Dosage,Route,

Frequency,etc.)

Classification INDICATIONS ADVERSE EFFECTSOF THE DRUGCONTRAINDICATI

ONS

NURSINGRESPONSIBILITIES

/PRECAUTIONS

Amikacinsulfate 500mgIV ANST(-)q12 x 7 days

Amino glycoside Indications: Serious

infectioncause bysensitiverestrains of Pseudomonasaeruginusa,E.coli,Proteus,Klebsiella,staphylococcus

Uncomplicated UTIcaused byorganismsusceptibleto less toxicdrugs.

Activetuberculosis, with other antituberculotics

Mycobacteri

CNS:-neuromuscular blockade

EENT:-ototoxicity

Contraindications: Contraindica

ted inpatientshypersensitive to drug or other aminogycosides.

Usecautiously inpatients withimpairedrenalfunction or neuromuscular disorders,in neonatesand infantsand inelderlypatients.

Obtain specimenfor culture andsensitivity testbefore givingfirst dose.

Evaluatepatients hearingbefore andduring therapy if he will bereceiving drugfor longer than 2weeks. Notifyprescriber if patient hastinnitus, vertigo,or hearing loss.

Correctdehydrationbefore therapybecause of increase risk of toxicity.

Watch for signsand symptomsof super infection

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um aviumcomplex(MAC)infection.

(especiallyURT), such ascontinued fever,chills, andincreased pulserate.

Cefuroxime750mg IVANST(-) q8

Cephalosporin(2 nd Generation)

Indications: Urinary tract

infections,Otitis media,

Severe

infections

CNS: Dizziness,headache, fatigue,paresthesia, fever,chills, confusionGI: Diarrhea, nausea,vomiting, anorexia,glossitis, bleeding,increased AST, ALT,bilirubin, LDH, alkalinephosphatase,abdominal pain, loosestools, flatulence,heartburn, stomachcramps, colitis, jaundiceGU: vaginitis, pruritus,candidiasis, increasedBUN, nephrotoxicity,renal failure, pyuria,dysuria, reversibleinterstitial nephritis

Contraindications: Sensitivity to

cephalosporins

Usecautiouslywith renalfailure,lactation,pregnancy.

Assess patientfor signs andsymptoms of infection

Assess for

anaphylaxis:rash, urticaria,chills, fever,dyspnea

Identify urineoutput

Assess bowelpattern daily

Monitor for bleeding

Celecoxib200mg 1 capBID

NSAID (non-steroidal anti-inflammatorydrug)

Indications Acute and

long-termtreatment of signs andsymptoms

CNS: headache, dizziness,somnolence, insomnia,fatigue, tiredness,dizziness, tinnitus,ophthamologic effects

Contraindications: Hypersensiti

vity to drugs severe

hepaticimpairment

Tell patient toreport history of allergic reactiontosulfonamides,aspirin,

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of rheumatoidarthritis andosteoarthritis

Management andtreatmentof post-surgical or dentalpain, andprimarydysmenorr heal

.

GI: Nausea, abdominalpain,dyspepsia,flatulence, GI bleed

Dermatologic :Rash, pruritus,sweating, dry mucousmembranes, stomatitis

3 rd trimester of pregnancy

NSAIDS Instruct patient

to report signsof GI bleeding.

Advice patientto immediatelyreport rash,unexplainsweight gain, or swelling.

Inform patientthat it may takeseveral daysbefore he feltconsistent painrelief.

Paracetamol500mg/tabPRN

Analgesic/Antipyr etics

Indications: Relief of

mild-to-moderatepain

Temporaryreduction of fever

CNS: weakness,fatigue,nervousness,sedation,drowsiness,dizziness,depression, tremor,headache, seizures

GI: Anorexia,nausea, vomiting,constipation, hepaticinsufficiency

Contraindications: Contraindica

ted withallergy toacetaminophen

Usecautiouslywithimpairedhepaticfunction,chronicalcoholism,pregnancy,lactation.

Assess patientsfever or pain:type of pain,location,intensity,duration,temperature

Assess allergicreactions: rash,urticaria; if theseoccur, drug mayhave to bediscontinued

Give with food or milk if GI upsetoccurs

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