Organic food and health – a multigeneration animal experiment

D a n i s h R e s e a r c h C e n t r e f o r O r g a n i c F a r m i n g Danish Research Centre for Orga Farming (DARCOF) coordinates Dan research into organic farming. purpose is to secure the opti benefit of the resources allocated the resear DARCOF is a so called ”research cent without boundaries” where t research qualifications is composed the scientists and institutes participat in the research programs. At moment there is six research progr in progress with a total of 33 projec More information on the research be found at www.darcof.dk obtained fr Danish Research Centre Organic Farm Research Centre Fou P.O. Box 50 •DK-8830 Tj Tel. +45 89 99 16 75 • Fax +45 89 99 16 E-mail: darcof[at]agrsci Organic food and health – a multigeneration animal experiment The overall objective is to determine, if conventional and organic food products show differences in effects on animal physiology, of a type and magnitude, that indicates that such products will affect humans differently. The agricultural treatments used are: 1. An organic cultivation treatment, with low input of nutrients through animal manure and use of catch crops, and no pesticides. 2. A conventional cultivation system, with high input of nutrients through mineral fertiliser and intensive use of pesticides. 3. A combination of 1 and 2, with low input of nutrients, primarily animal manure, and intensive use of pesticides. The treatments will be established on two sites. Wheat, potatoes and oilseed rape will be produced in Foulum, and carrots, kale and mature peas in Årslev. Vegetables and fruit will be processed and dried, wheat ground and baked, and oil will be produced from the rapeseed. The picture-developing properties of fresh plant material are examined by means of biocrystallization. Characteristic secondary metabolites are measured in feed material from each treatment. The major nutrients in the feed plants are determined, and the biological value of major protein sources of feed plants is assessed. Based on these results, three feed mixtures are prepared and analysed for concentrations of approximately 20 elements and 150 pesticides. Rats are fed with the three prescribed feed mixtures for two generations. Reproductive characteristics and weight gain are recorded. Groups of second generation of rats are selected for an intensive study, in which uptake and excretion of energy and protein and selected micronutrients are determined. Effect of the dietary treatments on the immunological, antioxidant, and health status of the rats will be studied. Data from the experiments are assembled and analysed using relevant models. DARCOF-project III.4 Organic food and health – a multigeneration animal experiment (Organic Health) Project leader Kirsten Brandt, Ph.D., Senior scientist Danish Institute for Agricultural Sciences, Department of Horticulture Kirstinebjergvej 10, Postboks 102, DK-5792 Årslev Phone: +45 63 90 43 43, Fax: +45 63 90 43 95 E-mail: [email protected] Project participants Erik Larsen, Hanne Lindhard Pedersen, Kristian Thorup- Kristensen, Jens Peter Mølgaard, Jens Henrik Badsberg, Charlotte Lauridsen, Henry Jørgensen, DIAS Hanne Nygaard Larsen, Susanne Bügel, Jens-Otto Andersen, KVL Hanne Frøkiær, Technical University of Denmark Lars Ove Dragsted, Danish Food Agency Vagn Gundersen, Risø National Laboratory. Archived at http://orgprints.org/00001703

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Page 1: Organic food and health – a multigeneration animal experiment

Dan

ish R

ese

arch

Cen

tre fo

r Org

ic F

arm

ing

Danish Research Centre for OrganicFarming (DARCOF) coordinates Danish

research into organic farming. Thepurpose is to secure the optimum

benefit of the resources allocated tothe research.

DARCOF is a so called ”research centre without boundaries” where the

research qualifications is composed bythe scientists and institutes participating

in the research programs. At the moment there is six research programs in progress with a total of 33 projects.More information on the research can

be found at www.darcof.dk or obtained from:

Danish Research Centre forOrganic Farming

Research Centre FoulumP.O. Box 50 •DK-8830 Tjele

Tel. +45 89 99 16 75 • Fax +45 89 99 16 73E-mail: darcof[at]agrsci.dk

Organic food and health – a multigeneration animal experiment

The overall objective is to determine, if conventional and organic food products show differences in effects on animal physiology, of a type and magnitude, that indicates that such products will affect humans differently. The agricultural treatments used are:

1. An organic cultivation treatment, with low input of nutrients through animal manure and use of catch crops, and no pesticides.

2. A conventional cultivation system, with high input of nutrients through mineral fertiliser and intensive use of pesticides.

3. A combination of 1 and 2, with low input of nutrients, primarily animal manure, and intensive use of pesticides.

The treatments will be established on two sites. Wheat, potatoes and oilseed rape will be produced in Foulum, and carrots, kale and mature peas in Årslev. Vegetables and fruit will be processed and dried, wheat ground and baked, and oil will be produced from the rapeseed.

The picture-developing properties of fresh plant material are examined by means of biocrystallization.

Characteristic secondary metabolites are measured in feed material from each treatment. The major nutrients in the feed plants are determined, and the biological value of major protein sources of feed plants is assessed.

Based on these results, three feed mixtures are prepared and analysed for concentrations of approximately 20 elements and 150 pesticides. Rats are fed with the three prescribed feed mixtures for two generations. Reproductive characteristics and weight gain are recorded. Groups of second generation of rats are selected for an intensive study, in which uptake and excretion of energy and protein and selected micronutrients are determined. Effect of the dietary treatments on the immunological, antioxidant, and health status of the rats will be studied. Data from the experiments are assembled and analysed using relevant models.

DARCOF-project III.4Organic food and health – a multigeneration animal experiment (Organic Health)

Project leaderKirsten Brandt, Ph.D., Senior scientist Danish Institute for Agricultural Sciences, Department of HorticultureKirstinebjergvej 10, Postboks 102, DK-5792 ÅrslevPhone: +45 63 90 43 43, Fax: +45 63 90 43 95E-mail: [email protected]

Project participantsErik Larsen, Hanne Lindhard Pedersen, Kristian Thorup-Kristensen, Jens Peter Mølgaard, Jens Henrik Badsberg, Charlotte Lauridsen, Henry Jørgensen, DIASHanne Nygaard Larsen, Susanne Bügel, Jens-Otto Andersen, KVLHanne Frøkiær, Technical University of DenmarkLars Ove Dragsted, Danish Food AgencyVagn Gundersen, Risø National Laboratory.

Archived at http://orgprints.org/00001703