OralogiK from BDD
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Transcript of OralogiK from BDD
![Page 1: OralogiK from BDD](https://reader034.fdocuments.in/reader034/viewer/2022042511/55d1eafabb61eb56708b4757/html5/thumbnails/1.jpg)
CONTROLLED DRUG DELIVERY with
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• Delivering pulsed or sustained release profiles at night after a defined lag period
• Adjustable lag from 1-8 hours to address specific therapeutic needs
• Works independently of pH and agitation
DELAYED DRUG RELEASE
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What’s the advantage?
Tablet in tablet works independently of drug core
Can use existing core formulation allowing rapid development
Barrier layer
Pulse or sustained drug core
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LIMITLESS FORMULATION OPPORTUNITIES
DELAY + PULSE eg. zaleplon for sleep
maintenance
IR + DELAY + PULSE eg. diclofenac for pain and
morning stiffness
DELAY + SR eg. verapamil for circadian
cardiovascular event
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SECONDARY APPLICATIONS OF OralogiK
Colon Delivery
Sustained Release
Complex Release Profiles (biphasic / triphasic)
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COLON DELIVERY Dissolution study simulating colon delivery
pH change
stomach small intestine colon
pH 1.2 pH 6.8 →
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SUSTAINED RELEASE Incorporation of drug into barrier layer affords a near zero order release profile as the layer erodes
Can be combined with a pulsed release technology for BIPHASIC release
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SUSTAINED RELEASE IVIVC correlation of erosion of SR formulation
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COMPLEX TRIPHASIC RELEASE PROFILES Combining immediate, sustained and delayed release
4 hr SR 6 hr SR
The 3 phases can be the same or different drugs
Addition of IR dose by film coating or compression layer
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Why choose OralogiK?
• Bring new consumer products affordably and quickly to market
• Bring new Rx products affordably and quickly to market
• Capitalise on your brand names with product line extension
• Patented products for lifecycle management
• Rapidly bring innovative products to the market
• Offer a novel health solution in highly competitive markets
WHAT CAN ORALOGIK DO FOR YOU
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T: (+44) 141 552 8791 www.bddpharma.com