Oral Lession Associated COVID-19 : Symptoms or …
Transcript of Oral Lession Associated COVID-19 : Symptoms or …
Oral Lession Associated COVID-19 : Symptoms or Complications
Drg. Rochman Mujayanto, Sp.PM
PENDIDIKAN : 1. SARJANA KEDOKTERAN GIGI UNIVERSITAS AIRLANGGA SURABAYA LULUS TAHUN 2001 2. PROFESI DOKTER UNIVERSITAS AIRLANGGA SURABAYA LULUS TAHUN 2004 3. SPESIALIS PENYAKIT MULUT UNIVERSITAS AIRLANGGA SURABAYA LULUS TAHUN 2016
PEKERJAAN : 1. 2011 - SEKARANG DOSEN FAKULTAS KEDOKTERAN GIGI UNISSULA, SEMARANG 2. 2011 – SEKARANG RS HERMINA PANDANARAN, SEMARANG 3. 2017 – SEKARANG RSI GIGI & MULUT SULTAN AGUNG SEMARANG 4. 2017 – SEKARANG RS GIGI & MULUT SOELASTRI SURAKARTA
ORGANISASI: 1. PENGURUS PUSAT IKATAN SPESIALIS PENYAKIT MULUT INDONESIA, BIDANG CONTINUING DEVELOPMENT EDUCATION &
PENGABDIAN KEPADA MASYARAKAT, PERIODE TAHUN 2017–20222. WAKIL KETUA PENGURUS IKATAN SPESIALIS PENYAKIT MULUT INDONESIA WILAYAH II (JAWA BARAT, JAWA TENGAH,
YOGYAKARTA, KALIMANTAN, KEPULAUAN RIAU) PERIODE TAHUN 2017-20223. PENGURUS WILAYAH JAWA TENGAH PERHIMPUNAN KONSELOR VCT HIV INDONESIA, BIDANG ORGANISASI DAN HUKUM,
PERIODE TAHUN 2019 - 20244. KEPALA DEPARTEMEN ILMU PENYAKIT MULUT FAKULTAS KEDOKTERAN GIGI UNIVERSITAS ISLAM SULTAN AGUNG5. KETUA TIM HIV/AIDS RUMAH SAKIT ISLAM GIGI & MULUT SULTAN AGUNG6. KONSELOR HIV/AIDS RUMAH SAKIT ISLAM GIGI & MULUT SULTAN AGUNG
Drg. Rochman Mujayanto,Sp.PM
Publikasi : 1. Mujayanto R, Indraswary R. Differential Diagnosis of COVID-19 Enanthema. Eur J Dent. 2020 Dec;14(S 01):S179-S181. doi: 10.1055/s-0040-1719210. Epub 2020 Nov 26. PMID:
33242912; PMCID: PMC7775208.2. Kontributor buku : Panduan Praktik Klinis Ilmu Penyakit Mulut Edisi ke-1 Kolegium Ilmu Penyakit Mulut Indonesia Ikatan Spesialis Penyakit Mulut Indonesia.
DOI: https://doi.org/10.32793/monograph.v1i1.6303. Kontributor buku : Petunjuk Teknis Pelayanan Kesehatan Gigi dan Mulut di Fasilitas Kesehatan Tingkat Pertama Pada Masa Adaptasi Kebiasaaan Baru – Kementerian Kesehatan RI
20214. Mujayanto R. Pencabutan Gigi : Kondisi Kompromis Medis. In: Amalina R, Woroprobosari NR, eds. Pencabutan Gigi Dengan Penyulit. 1st ed. EF Press Digimedia; 2019:1-16.5. Mujayanto R. Komplikasi Diabetes Melitus Pada Mukosa Mulut. In: Amalina R, Septiana L, eds. Diabetes Dental Care. 1st ed. EF Press Digimedia; 2019:17-26.
ORAL LESSION ASSOCIATED COVID-19 : SYMPTOMS OR COMPLICATIONS
DRG. ROCHMAN MUJAYANTO, SP.PM
DENTAL SEMINAR UMS
ZOOM MEETING, JUNE 2TH 2021
Highly Pathogenic HCoV : ReviewZhu, Z., Lian, X., Su, X. et al. From SARS and MERS to COVID-19: a brief summary and comparison of severe acute respiratory infections caused by three highly pathogenic human coronaviruses.
Respir Res 21, 224 (2020). https://doi.org/10.1186/s12931-020-01479-w
COVID-19 and its Modes of TransmissionKaria, R., Gupta, I., Khandait, H. et al. COVID-19 and its Modes of Transmission. SN Compr. Clin. Med. 2, 1798–1801 (2020).
https://doi.org/10.1007/s42399-020-00498-4
Atukorallaya DS and Ratnayake RK (2021) Oral Mucosa, Saliva, and COVID-19 Infection in Oral Health Care. Front. Med. 8:656926. doi: 10.3389/fmed.2021.656926
Signs & SimptomsCOVID-19
Into Respiratory
Extra Respiratory
•Oral mucosal lesions
•Neurological dysfunctions, (such as loss of smell, loss of taste)
•Headache
•Associated myofascial pain
Atukorallaya DS and Ratnayake RK (2021) Oral Mucosa, Saliva, and COVID-19 Infection in Oral Health Care. Front. Med. 8:656926. doi: 10.3389/fmed.2021.656926
Into Respiratory
• Cough
• Shortness of breath or trouble breathing
Extra Respiratory
• Oral mucosal lesions
• Neurological dysfunctions, (such as loss of smell, loss of taste)
• Headache
• Associated myofascial pain
Iranmanesh, B, Khalili, M, Amiri, R, Zartab, H, Aflatoonian, M. Oral manifestations of COVID‐19 disease: A review article. Dermatologic Therapy. 2021; 34:e14578. https://doi.org/10.1111/dth.14578
Oral Mucosal Lesions of COVID-19
Aphthous-like lesions
•Herpetiform lesions
•Ulcer and erosionWhite/Red
plaques
Erythema/ Enanthem
EM-like lesions
Angina bullosa-like
lesions
Melkerson-Rosenthal syndrome
Vesicles and pustules
Petechiae
Nonspecific lesions
(mucositis)
Atukorallaya DS and Ratnayake RK (2021) Oral Mucosa, Saliva, and COVID-19 Infection in Oral Health Care. Front. Med. 8:656926. doi: 10.3389/fmed.2021.656926
Orofacial Symptoms of
COVID-19
Headache
Myofacialpain
Burning sensation of the oral
mucosa
Loss of taste
Loss of smell
Dry mouth
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DIFFERENTIAL DIAGNOSIS
ORAL MANIFESTATIONS OF COVID-19
Suspected COVID-19
● Oral herpes (primary or recurrent)
● Herpes zoster
● Varicella
● Herpangina
● Hand Foot & Mouth Diseases
● Measles
Probable COVID-19 (Lost of Taste)● Side effects of drugs
● Nutritional deficiencies
● Diabetes mellitus
● Hypotyrodism
● Perniciosa anemia
● Sjorgen syndrome
● Crohn Diseases
Covid-19 Symptomatic Patients With Oral Lesions
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Favia G, Tempesta A, Barile G, Brienza N, Capodiferro S, Vestito MC, Crudele L, Procacci V, Ingravallo G, Maiorano E, Limongelli L. Covid-19 Symptomatic Patients with Oral Lesions:
Clinical and Histopathological Study on 123 Cases of the University Hospital Policlinic of Bari with a Purpose of a New Classification. Journal of Clinical Medicine. 2021; 10(4):757.
https://doi.org/10.3390/jcm10040757
Atukorallaya DS and Ratnayake RK (2021) Oral Mucosa, Saliva, and COVID-19 Infection in Oral Health Care. Front. Med. 8:656926. doi: 10.3389/fmed.2021.656926
Brandini, D.A., Takamiya, A.S., Thakkar, P., Schaller, S., Rahat, R. and Naqvi, A.R. (2021), Covid‐19 and oral diseases: Crosstalk, synergy or association?. Rev Med Virol. https://doi.org/10.1002/rmv.2226
La Rosa GRM, Libra M, De Pasquale R, Ferlito S and Pedullà E (2021) Association of Viral Infections With Oral Cavity Lesions: Role of SARS-CoV-2 Infection. Front. Med. 7:571214. doi: 10.3389/fmed.2020.571214
Immunopathogenesis
Gupta, A., Madhavan, M.V., Sehgal, K. et al. Extrapulmonary manifestations of COVID-19. Nat Med 26, 1017–1032
(2020). https://doi.org/10.1038/s41591-020-0968-3
cytokine release syndrome (CRS)
Guo, M., Tao, W., Flavell, R.A. et al. Potential intestinal infection and faecal–oral transmission of SARS-
CoV-2. Nat Rev Gastroenterol Hepatol 18, 269–283 (2021). https://doi.org/10.1038/s41575-021-00416-6
Oral Lession Associated COVID-19 : Symptoms or Complications ?
An association between oral
diseases and SARS-CoV-2 infection is still unclear and currently poorly
investigated
The appearance of such lesions could be related to the direct or indirect action of SARS-CoV-2
over the oral mucosa cells, coinfections, immunity
impairment, and adverse drug reactions
The oral signs and symptoms presented by patients with
Covid‐19 are a direct result of SARS‐CoV‐2 infection or
secondary disorders facilitated by systemic damage, alterations
in the immune system, or adverse effects of treatment and
require further investigation with larger cohort sizes
La Rosa GRM, Libra M, De Pasquale R, Ferlito S and Pedullà E (2021) Association of Viral Infections With
Oral Cavity Lesions: Role of SARS-CoV-2 Infection. Front. Med. 7:571214. doi:10.3389/fmed.2020.571214
La Rosa GRM, Libra M, De Pasquale R, Ferlito S and Pedullà E (2021) Association
of Viral Infections With Oral Cavity Lesions: Role of SARS-CoV-2 Infection.
Front. Med. 7:571214. doi:10.3389/fmed.2020.571214
Brandini, D.A., Takamiya, A.S., Thakkar, P., Schaller, S., Rahat, R. and
Naqvi, A.R. (2021), Covid‐19 and oral diseases: Crosstalk, synergy or
association?. Rev Med Virol. https://doi.org/10.1002/rmv.2226
CONCLUSION
Always ask about the symptoms of ageusia & anosmia
The SARS-COV-2 PCR examination is the standard standard
Teleconsultation with Oral Medicine specializes
THANK YOUROCHMANMUJAYANTO
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