Hosted by

&KISAR (Karnataka Chapter of ISAR)

ISMAAR (The International Society for Mild

Approaches in Assisted Reproduction)

Optimizing ART Outcome

– through Individualized

Protocols @

forthcoming International Congress on

4th and 5th February 2012at Hotel Atria, Bengaluru

Dear Friends

“A scientific truth does not triumph by convincing its opponents and making them see the light, but rather because its opponents eventually die and a new generation grows up that is familiar with it.”

Max Planck

ART is associated with health risks to the mother and child. Today, ovulation induction protocols involve several controversies in the drugs used, types of protocol and the risks involved with it. This update on ovarian stimulation will discuss many current strategies for ovarian stimulation, individual variability in ovarian response and its possible implications on oocyte and embryo quality and endometrial receptivity.

Being aware of the complex interplay between the ovarian physiology, ovarian stimulation, in vitro embryo development and IVF outcome will help in optimizing the ART outcome.

This conference aims to present knowledge that can be translated into daily practice by identifying patients who require conventional or mild stimulation for an optimal outcome.

Furthermore, the conference will address the protocols and laboratory systems needed to offer low-cost IVF in developing countries.

Jean Piaget has rightly said “Scientific knowledge is in perpetual evolution; it finds itself changed from one day to the next.”

We await your participation.

Warm Regards

Madhuri Patil C. Sharath Kumar Bina Vasan Devika Gunasheela Geeta NargundPresident Secretary Treasurer Joint Secretary PresidentKISAR (KarnataKa Chapter of ISar) ISMAAR

Course ObjectivesAt the conclusion of this conference the participants should be able to:

• know the effects and risks of Ovulation Induction• critically evaluate the prediction and prevention of OHSS• understand complexity of different ovulation induction protocols in terms of drug and dose used

and desired endpoint• know that individual differences exist in response to ovarian stimulation which are related to

intrinsic ovarian differences and its implications• critically evaluate the value of new methods – Mild and Natural cycle IVF• understand the implications of single embryo transfer• evaluate the value of IVM• identify the best methods to test ovarian reserve and monitor ovulation Induction cycles• understand the implications of low-cost IVF for developing countries

Who should attend?

• Infertility and ART specialist

• Obstetrician and Gynecologist

• Clinical embryologist

• Postgraduate students

Day 1 – Saturday 4th February 2012Session 1 – 9.00 – 10.00 AM effects of conventional CoS on the outcome of art Think before you discard the old……………9.00 – 9.15 AM Impact of COS on oocytes and embryos – Satish Adiga9.15 – 9.30 AM Implications of ovarian stimulation on endometrial receptivity - Bina Vasan9.30 – 9.45 AM DiscussionSession 2 - 09.45 – 10.45 AMOvulation Induction strategiesexciting options for the future09.45 – 10.00 AM Individualizing ovarian stimulation in ART – Korula George10.00 – 10.15 AM Use of oral anti-oestrogens in ART cycles – Prof. Svend Lindenberg10.15 – 10.30 AM OHSS free clinic - Is it a dream? – Reeta Biliangady10.30 – 10.45 AM Discussion10.45 – 11.15 AM Coffee Break11.15 – 11.45 AM Keynote Address

Chairpersons: Kamini Rao, Madhuri PatilMild ART should it become the norm? – Prof. Geeta Nargund

11.45 – 12.15 PM Inauguration12.15 – 1.15 PM

Panel DiscussionStump the experts – point counterpointModerator – Madhuri PatilPanel Members – Svend Lindenberg, Mette Munk, Anuja Kamat, Deepika K, Fessy Louis, Mala Arora, Shobhana Patted

1.15 – 2.15 PM LunchSession 3 – 2.15 – 3.30 PMAll about Mild ARTChanging Attitudes Changing practices2.15 – 2.45 PM IndicationsandroleofnaturalcycleandmodifiednaturalcycleIVFtoday–Prof.GeetaNargund2.45 – 3.00 PM From aggressive to mild stimulation – Is it better? – Kannaki C V3.00 – 3.15 PM Luteal Phase supplementation on Mild/natural cycle ART – Bharati Dorepatil3.15 – 3.30 PM DiscussionSession 4 - 3.30 – 4.00 PM Paper Presentation - Best 3 postersSession 5 - 4.00 – 5.15 PM4.00 – 5.00 PM Debates

Chairpersons: Prof. Willem Ombelet, Prof. Svend Lindenberg4.00 – 4. 30 PM Debate 1

GnRH agonist or Antagonist – which is better in Mild ART?GnRH agonist – B. RameshGnRH Antagonist – Nirmala R

4.30 – 5.00 PM Debate 2Will mild stimulation replace conventional COS in ART practice?For – Sunita TandulwadkarAgainst – Nandita Palshetkar

5.00 – 5.15 PM Discussion5.15 – 5.45 PM Keynote Address

Chairpersons: Geeta Nargund, Dhiraj GadaLegal Issues in Infertility Practice – Kamini Rao

5.45 – 6.00 PM Discussion

Day 2 – Sunday 5th February 2012Meet the experts – Breakfast Session8.00 - 9.00 AM Topics

1. Explore the protocols - Experts: Prof. Geeta Nargund, Prof. Willem Ombelet, Kamini Rao2. IVM – When and how - Experts: Prof. Svend Lindenberg, Shreyas Padgaonkar, Devika Gunasheela3. Lab aspects of ART - Prof. Mette Munk, Vyjayanthi, Satish Adiga

Session 6 – 9.00 – 10. 15 AMMild Stimulation – Varied options in varied situations 9.00 - 9.15 AM Minimal stimulation protocols in IUI – Prof. Willem Ombelet9.15 – 9.30 AM Natural cycle/Mild stimulation in women with poor ovarian reserve/oocyte donors – Abha Majumdar9.30 – 9.45 AM Minimal stimulation in women with PCOS – Sonia Mallik9.45 – 10.00 AM Role of mild stimulation in fertility preservation in young cancer patients – Mandakini Parihar10.00 – 10.15 AM Discussion10 .15 – 10.45 AM Coffee BreakSession 7 – 10.45 – 12.00 PMUncertainties with IVM – Would they resolve soon?10.45 – 11.15 AM Keynote Address

Does IVM with mild stimulation improve outcome in PCOS? – Prof. Svend Lindenberg11.15 – 11.30 AM IVM in natural and FSH primed cycles – Devika Gunasheela11.30 – 11.45 AM IVM & fertility preservation in Cancer patients – Prof. Mette Munk11.45 – 12.00 PM DiscussionSession 8 – 12.00 – 1.15 PMembryos - are they different?12.00– 12.15 PM Ovarian stimulation and embryo quality - Less is more – Prof. Mette Munk12.15 – 12.30 PM Non invasive assessment of embryo - Does it improve embryo selection and is it cost effective in Indian

Scenario? - Vyjayanthi12.30 – 12.45 PM With Mild ART are we moving towards SET – Shreyas Padgaonkar12.45 – 1.00 PM Are Mild ART derived blastocysts more favorable than conventional COS derived ones? – Srinivas MS 1.00– 1.15 PM Discussion1.15 – 2.00 PM LunchSession 9 – 2.00 – 3.15 PMSafety and affordability – “Do no harm – to the patient and to her pocket”2.00 – 2.15 PM Affordability and access to ART in India – Manish Banker2.15 – 2.30 PM Soft protocols for Indian population – Dhiraj Gada2.30 - 2.45 PM Natural cycle IVF - Is it effective and cost effective? – Nalini Mahajan2.45 – 3.00 PM Discussion3.00– 3.30 PM Keynote Address

Low cost IVF in developing countries – What does it Imply? – Prof. Willem Ombelet3.30 – 4.30 PM Panel Discussion

Ground realities – Can our patients benefit?Impact of Milder stimulation upon indicators of benefit in Indian scenario – efficacy, safety, time, cost and qualityModerator – Mirudhubashini GovindarajanPanel Members – Prof. Willem Ombelet, Abha Majumdar, Asha Gangane, B.R Desai, Jyoti Menon, Kallappa Mavintop, Nivedita Shetty

Session 10 – 4.30 – 5.45 PMSelect Investigations in select situations - Can it reduce the burden?4.30 – 4.45 PM Stem Cells and Ovarian Reserve - Deepa Bhartiya 4.45 – 5.00 PM Assessment of ovarian reserve and its implications on selecting an ideal protocol for COS –

Padmarekha Jirge5.00– 5.15 PM Can use of advanced ultrasound technology make a difference in investigating and treating? –

Prof. Geeta Nargund5.15 – 5.30 PM RoleofofficehysteroscopyinMildARTprograms–C.SharathKumar5.30 – 5.45 PM Discussion5.45 PM Valedictory Session

ISMAAR BOARD KISAR BOARDGeeta Nargund Madhuri Patil Rene Frydman C. Sharath KumarBart Fauser Bina Vasan Stuart Campbell Devika Gunasheela Osama Kato B. R. Desai Svend Lindenberg Srinivas MS RC Chian Asha GanganeWillem Ombelet Satish AdigaPasquale Patrizio Reeta Biliangady

FacultyInternationalProf. Geeta NargundProf. Mette MunkProf. Svend LindenbergProf. Willem Ombelet

NationalAbha MajumdarAnuja KamatAsha GanganeB. RameshB.R DesaiBharti DorepatilBina VasanDeepa BhartiyaDeepika KDevika GunasheelaDhiraj GadaFessy LouisJyoti MenonKallappa MavintopKannaki C VKamini RaoKorula GeorgeMadhuri Patil

Organizing CommitteePATRONSDr. Kamini Rao Dr. Sulochana Gunasheela Dr. Pratap Kumar

SCIentIfIC CoMMItteeDr. Kamini RaoDr. Madhuri PatilDr. Reeta Biliangady

fInanCeDr.Bina VasanDr. C Sharath KumarDr. Devika Gunasheela

CaterInG CoMMItteeDr. Jyoti MenonDr. Kallappa MavintopDr. Sowmya Dinesh

traVeL/tranSport/ACCOMMODATIONDr. Srinivas MSDr. B R DesaiDr. Shobhana Patted

reGIStratIon CoMMItteeDr. Nirmala RDr. Asha GanganeDr. Puneeth Rangaraj

AUDIOVISUALDr. Madhuri PatilDr. Satish AdigaDr. Varsha Roy

traDe & eXhIBItIonDr. B. RameshDr. Vanitha MetgudDr. Rajesh Bhaktha

free paperSDr. SS VasanDr. Roopa

ConGreSS eXpenSeS:

earLY reGIStratIon (before 15 January, 2012)

Consultants Both Days - ` 2,500/-

One Day - ` 1,250/-

PG Students ` 1,500/-

Late reGIStratIon ( till 3 february, 2012)

Consultants - Both Days - ` 3,000/-

One Day - ` 1,500/-

Spot reGIStratIon

Consultants - Both Days - ` 3,500/-

One Day - ` 2,000/-

Meet the eXpertS

` 500/-

*Registration does not include accommodation.

Send in your PosterTopic: Ovarian StimulationLast Date for Submission – 25th January, 2012Abstracts to be e-mailed to kisar.office@gmail.comdrmadhuripatil59@gmail.com

Instructions for Poster presentation:• Maximum Size of poster should be 3 feet wide and 4 feet

in height• Poster should be put up by 9 AM on 4th February 2012• One person can present only 1 poster• Presentershavetobepresentatthespecifiedtime

announced during the conference for judging• Posters should be removed by 5.30 PM on 5th February

2012• Best 3 posters will be allowed oral presentation for

8 minutes on 4th February between 3.30 – 4.00 PM

Mala AroraMandakini PariharManish BankerMirudhubashini GovindarajanNandita PalshetkarNalini MahajanNirmala RNivedita ShettyPadmarekha JirgeReeta BiliangadySatish Adiga Shobhana PattedSharath Kumar C Shreyas PadgaonkarSonia MalikSrinivas MSSunita Tandulwadkar Vyjayanthi