Opportunistic pathogen

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Opportunistic pathogen Commensal organism Candida albicans superficial and systemic infections ~ 10,000 deaths per year in U.S.A.

description

Candida albicans. Commensal organism. Opportunistic pathogen. superficial and systemic infections ~ 10,000 deaths per year in U.S.A. Yeast. Cell Morphologies of C. albicans. Pseudohyphae. Hyphae. Yeast. Pseudohyphae/hyphae. Environmental Control of Morphogenesis. Serum, 37 o C - PowerPoint PPT Presentation

Transcript of Opportunistic pathogen

Page 1: Opportunistic pathogen

• Opportunistic pathogen

• Commensal organism

Candida albicans

superficial and systemic infections~ 10,000 deaths per year in U.S.A.

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Cell Morphologies of C. albicans

Hyphae

PseudohyphaeYeast

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Environmental Control of Morphogenesis

Serum, 37o CpH > 7Starvation

Yeast Pseudohyphae/hyphae

YPD or YNB medium30o C

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Yeast Cell Division Cycle

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Actin Cables and Actin Patches

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Yeast Cell Division Cycle

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Environmental Control of Morphogenesis

Serum, 37o CpH > 7Starvation

Yeast Pseudohyphae/hyphae

YPD or YNB medium30o C

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Light Microscope

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Hyphal Formation in Candida albicans

Light Microscopy Fluorescence Microscopy ofHWP1-GFP gene