Professor Ole Petter OttersenRector of the University

Life Science at UiOperspective

n

O – a long term g

Six messages to takeSix messages to take

•The Life Science Initiativone priority of the Univerone priority of the Univer•The initiative is inextrica

f iliti l d fnew facilities planned forspot in Gaustadbekkdale•The initiative builds on s•The initiative addressesNorway and in the globafirmly coupled to innovatfirmly coupled to innovat•The initiative unites regiinternational players – itinternational players – it interinstitutional, and inte

homehome

ve is the number rsity of Oslorsity of Oslo ably coupled to the

th l t il blr the last available enstrengths urgent needs in gl community and is ion competenceion competence ional, national, and is interdisciplinaryis interdisciplinary,

ernational

Significant volume - wactivityactivity

InstDept. Mol. Biosciences

InstituDept Chemistry

Dept. BiologySchool of Pharmacy

InstituDept. Chemistry

widespread

Institute of Health and Society

titute of Basic Medical Sciences

ute of Clinical Medicineute of Clinical Medicine

Excellence in Life SThe University is now hostFour Centers of Excellence

ancerbiomed.net

CBtre for

www cees no

tre forcer Biomedicine

Prof. Harald Stenmark

www.cees.no

CEESCEESCentre for

Sciencesing e within the Life Sciences

www cmbn nowww.cmbn.no

CMBNCMBNCentre forMolecular Biologyand Neuroscience

Prof. Tone Tønjum

www cir uio nowww.cir.uio.no

CIRCentre forCentre for Immune Regulation Prof. Ludvig S

RC Advanced grants

Prof. Harald A. Stenmark, headERC Advanced Grants 2008 - project "The PI3K

of. Harald Stenmark

Prof. Ludvig Sollid, head of theERC Ad d G t 2010 j t "C li

rof L d ig Sollid

ERC Advanced Grant 2010 - project "Coeliaformation".

rof. Ludvig Sollid

Prof. Trygve Helgaker, at theChemistry» at UiTø and UiO. CERC Advanced Grant 2010 Helgaker's researERC Advanced Grant 2010. Helgaker's researfor large molecular systems, containing hundre

s in Life Science

d of the CoE «Center for Cancer BiomedicK-III complex: Function in cell regulation and tumour suppression

CoE «Center for immune regulation».di U d t di h f i t i d i tac disease: Understanding how a foreign protein drives aut

CoE «Centre for Theoretical and ComputComputational chemistry - future life scienrch is directed towards the development of efficient computationarch is directed towards the development of efficient computationads or thousands of atoms such as those encountered in biologica

National centres for aequipment at UiO - LNational Financing Initiativ- Competitive calls - recent centSciences at UiO:

Norwegian High-ThroughpNorwegian High ThroughpUiO/OUS (2010)

UiO d– UiO node– OUS node

A National Subcellular Ima– Advanced microscopy and imaging techniques –

advanced research Life Scienceve for Research Infrastructutres established within the Life

put Sequencing Centre atput Sequencing Centre at

aging Platform at UiO (2011g g (developed from the Oslo-NorMIC technology platform

pFRI - Biological and Medicaal Science

Lesson 1

Building strong resis a long term effois a long-term effo

search environments rtrt

What thesethese scientscientcommcomm

Long-term eLong term einternationalb i t fbeing part oflasting tradit

have

ists inists in mon ?mon ?

effortsefforts, lly active, f lf long-tions

Lesson 2

Investing in researl d t dleads to more and

rch b tt ibetter science

Important

1000 -

Important investmentsFUGE + CoEFUGE + CoE

500 -Number publications

UiO-productiop on - the PubMed database

Quality indicators - Thclear increase in citations of Norwclear increase in citations of Norwhighly significant increase in cita

he new biologywegian contributionswegian contributionstions from the Oslo area

Molecular biology Oslo (UiO+O

Molecular biology Norway

olumeNIFU statistics of the NNIFU statistics of the N

l l bi lolecular biology

orwegian landscapeorwegian landscape

#1

Lesson 3

Strong research - i

something is hap... something is hap

innovations follow

peningpening

The first UiO innovaThe first UiO innova- Life Sciences

I S dli 2011• Inger Sandlie, 2011 pr

H lb i• Human albumin superprolonging the life timeprolonging the life time

• Cooperation with NovoCooperation with Novo

ation prizeation prize

i irize winner

bi drbinders -e of drugse of drugs

ozymesozymes

DnB NOR’s InnovatDnB NOR s Innovat- Life Sciences• September 2011, PCI

awarded both the presNOR’s Innovation prizeNOR s Innovation prizethe Peoples award.

• PCI Biotech has develi d t t dunique and patented p

drug delivery technolodrug delivery technolocancer therapy and oth

tion prizetion prize

Biotech was stigious DnB e 2011 ande 2011 and

loped a h t h i lphotochemical gy for use ingy for use in her diseases.

- a success

he Norwegian biotech company AlgetS h i Ph AG th 1 bilayer Schering Pharma AG worth 1 bil

sfull company within OC

a recently signed an agreement with lli US $llion US $

in Norwegian

Last 5 years: the number of Nbiotech companies has increbiotech companies has incre50 %

n Life Science companie

«It is companies like these we shall live on in the future»

Norwegian eased with

shall live on in the future»CEO, The Research Council of Norway,Arvid Hallén

eased with

GNIFICANT GROWTH

New Inventions New Paatent Applications Commercializat

ORWAYS LEADING TTO MF COMMERCIALIZATIONS

MEASURED IN NUMBER S

Lesson 4

The emergence of in the Oslo regionin the Oslo region

a Life Science cluste

Biotechnology in OAn emerging promising clu

June 2008 Gen

An emerging promising clu

• June 2008 GenOslo as an emehighly ranked.

It's certainly no«It's certainly nobiotech cluster, bu

the effortsthe efforts bioscience segm

Norway are i

Oslouster

nome Technology identified

uster

nome Technology identified erging new biotech cluster

ot the biggestot the biggest ut for its size,

to cement ato cement a ment here in impressive».

ow to proceed?ow to proceed?

Three strategies aThree strategies a1. new ways of organizing interfac2. new types of international resea3 new premises for multidisciplina3. new premises for multidisciplina

at UiO:at UiO:ultary research

arch centersary researchary research

.Organization - newgocused research ar

i hi l l lif i- within molecular life sciMED ODThe Faculty of

MedicineThe Faculty of Dentistry

MoleculScience

w interfacultary yreaences

MNThe Faculty of Mathematics and Natural Sciences

lar Life e

Organizational strOrganizational strResearch collaboratResearch collaboratuniversity and hosp

rengthrengthtion betweention between itals

New types of internh tesearch centres

From moleculeFrom molecule

Clear interdiscipliClear interdiscipli

national

to patientto patient

inary profileinary profile

premises for ltidi i limultidisciplinary

Life ScienceLife Sciencencluding chemistryncluding chemistry

and pharmacyAn instrument for trengthening Norwegian ife Scienceife Science,

panning from chemistry to i di iiomedicine,

with Norways largest it l i hbospital as neighbor

with Norways largest D t t f i f tiDepartment of informatics as eighbor

22

The entire va

cienceaculty

Mfa!aculty fa

«a comprehensive Life Scienc

!

lue chain

edicalacultyaculty

ce Cluster»

HealthHealthEnvironment

InnovationInnovation

nspired by .... t t t f MITstrategy report from MIT

convergence - a blueprint fo• Convergence means a broa

can be conducted.• A major beneficiary of conv

or innovationad rethinking of how all scientific researc

ergence will be in biomedicine

A great future opportunity

R t W C B øRector W.C. Brøgge

”Hvert VidenskaLite at ens og Literaturens og Storværk er for Folk som vort etsikrere Værn forsikrere Værn forog vor Selvstænend baade Armeend baade ArmeKanoner og TorpP kib FPanserskibe og F

A small natidifference s

er:

bens, K nstens Kunstens et lidet t langt r vor Frihed r vor Frihed ndighed, eer og eer og pedoer og F i ” Fæstninger”

ion may make a simply because it has

Six messages to takeSix messages to take

•The Life Science Initiatone priority of the Unive•The initiative is inextricnew facilities planned fospot in Gaustadbekkdalspot in Gaustadbekkdal•The initiative builds on •The initiative addresses•The initiative addressesNorway and in the globaTh i iti ti it•The initiative unites reg

international players – itinterinstitutional, and int•The absorption capacit

homehome

tive is the number ersity of Oslo ably coupled to the y p

or the last available enenstrengths urgent needs ins urgent needs in al community i l ti l dgional, national, and

t is interdisciplinary, ternational ty is not a limiting

TaaThank you for your attentionattention