Objective - cds.ismrm.org · LP et al. Med Osteoarthritis oelasticity in ... al sagittal ima e...
Transcript of Objective - cds.ismrm.org · LP et al. Med Osteoarthritis oelasticity in ... al sagittal ima e...
Evalu
1Radiolog
Medical C
Tec
Objectishown to
of cartilag
measure f
was to inv
measured
Methodcartilage
viscosity
of the sam
image seq
120×120
1000, and
specimen,
trochlea w
Region of
Resultsdistortion
relaxation
respective
mean visc
were stati
Discussjoint funct
significan
support to
degenerat
cartilage a
needed to
ADC and
non-invas
Referen440-4. Li
Li X et al.
uation of visc
Takak
gical Science, To
Center, Anesaki,
chnology, Tsukub
ve: Apparent
correlate main
ge correlate wit
for the mecha
vestigate the co
by indentation
ds: ADC of
was measured
coefficient we
mples was acq
quence with th
mm, matrix 2
d 1500 s/mm2
, medial and la
were analyzed
f interest was d
s: Morphologic
correction wer
n time and visc
ely, p<0.01, Fig
cosity coefficie
stically signifi
sion and Cotion, where it a
nt correlation ob
o the notion tha
ive cartilage. F
and incorporati
confirm this. I
viscoelasticity
sive method of
nces: Mlynár
i LP et al. Med
. Osteoarthritis
coelasticity inko Aoki1, Atsuya
okyo Metropolita
Chiba, Japan, 3B
ba, Ibaraki, Japa
diffusion coef
nly with water c
th viscoelastici
anical strength
orrelation betw
n testing.
porcine knee
d by using a 3
re measured u
quired using a
he following pa
56×256, slice
(Total scan tim
ateral femoral c
d for both MR
drawn over the
cal sagittal ima
re shown in fig
osity coefficien
g. 2-3). The me
ent values show
cant (p<0.05).
onclusion: acts as a shock
bserved betwe
at ADC can be
Further studies
ing biochemica
In conclusion,
y was observed
assessing carti
rik V et al. J M
dical Engineeri
s and Cartilage
n early degena Watanabe2, Nao
an University, Ar
Biomedical Sens
an, 4Radiology, S
fficient (ADC)
content in carti
ity of cartilage
of cartilage. T
ween ADC and
(n =20, age
3-Tesla MRI .
sing an indent
a single shot
arameters: TR/
thickness 3.0
me 1 min 48 se
condyle as wel
R imaging an
whole area of
age and ADC m
gure 1. ADC w
nt (R2=0.7532
ean relaxation
ws on table 1. A
Cartilage play
k absorber durin
en ADC and vi
also useful for
including kne
al and histolog
a significant c
d, indicating tha
ilage viscoelas
Magn Reson Ima
ng & Physics 2
e 2007; 15(7): 7
nerative cartotaka Nitta3, Ak
rakawa-ku, Tokyo
sing and Imaging
Saitama Medical
of cartilage ha
ilage. As water
e, ADC can be
The aim of this
viscoelasticity
e 6 months)
. Relaxation t
ation device T
spin echo-ech
/TE 4000/47 m
mm, b values
ec). Four sites
ll as medial an
nd indentation
superficial lay
mapping with
was correlated w
and 0.6894,
time values an
All of these dif
ys a critical rol
ng joint loadin
iscoelasticity l
r the evaluation
es with degene
gical analysis a
orrelation betw
at ADC can ser
sticity.
aging 2003; 17
2008; 30: 182–
789-797
tilage using aira Furukawa1, a
o, Japan, 2Ortho
g, National Insti
l University Hosp
as been
r content
a useful
study
y
articular
time and
The ADC
o planar
ms, FOV
s 0, 700,
s in each
nd lateral
testing.
yer.
with
nd the
fferences
e in
ng. The
ends
n of
erative
re
ween
rve as a
7(4):
–189.
Figw
Fir
Fiv
apparent diffand Mamoru Niit
opedic Surgery, T
tute of Advanced
pital, Iruma-gun
g. 1 MR imagwith distortion
ig. 2 Correlatirelaxation tim
ig. 3 Correlativiscosity coef
fusion coeffictsu4
Teikyo University
d Industrial Scie
n, Saitama, Japa
ge and ADC mn correction
tion between Ame
tion between Afficient
cient
y Chiba
ence and
n
mapping
ADC and
ADC and
3299Proc. Intl. Soc. Mag. Reson. Med. 20 (2012)