Late-Onset Circulatory Dysfunction After Thyroid Hormone ...
Nutrition and Metabolism Dysfunction: Thyroid and Adrenal Disorders Bringing it all together!
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Transcript of Nutrition and Metabolism Dysfunction: Thyroid and Adrenal Disorders Bringing it all together!
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Nutrition and Metabolism Dysfunction: Thyroid and Adrenal
Disorders
Bringing it all together!
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Hyperthyroidism
• The signs and symptoms are mainly a result of what two things?– Hyper-metabolism– Overly sensitive sympathetic nervous system
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TSH LEVELSThe body senses that there is too much thyroid hormone and via the negative feedback loop, inhibits secretion of TSH.
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Thyroid/Adrenals
• What would be the implications for removal of the pituitary gland?
• The hypothalamus and anterior pituitary are integral to the hormone cascade and negative feedback process!
• Would need replacement of both steroids and thyroid hormone
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Thyroid Hormone Replacement
Why was Mr. Bill Loney on the same home going medications that Kathy Twohy takes?
Bill was put into a hypothryoid state via removal of his thyroid gland. Kathy was put into a hypothyroid state by autoimmune destruction of her thyroid gland and therefore both needed replacement.
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Hypothyroidism
• Give a description of a patient who has obvious hypothyroidism (clothes, hair, face, gender, speech patterns)
• Jacket, thin hair, thick tongue and facial edema, slow/slurred speech, female, lethargic and forgetful
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Thyroid Storm
• What is the most dangerous aspect of thyroid storm?
• Massive sympathetic outflow and the cardiac implications of it
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Addisonian Crisis
• What are three things a patient with Adrenocortical insufficiency should never leave home without?
1. Med alert bracelet2. IM Cortisone (syringe/medication)3. Card with a list of current meds/dosages and what to do in case of an emergency
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Other questions…
What do we call the cluster of signs and symptoms that we expect to see for a patient on high doses of Prednisone or other corticosteroids?
Cushing’s Syndrome
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Questions
• What questions/clarifications do you have or need from the modules?
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Parathyroid gland
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Purpose: Maintain calcium and phosphorus
balance• Parathyroid hormone
maintains an adequate amount of calcium in the blood
• Major cause of hyperparathyroidism: benign parathyroid tumor
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Hyper-parathyroidism
• Will have increased levels of calcium in the serum
• Loss of calcium from bones– Bone fractures
• Altered cardiac electrical conduction• Changes in personality, fatigue• Increased blood clotting• Risk for kidney stones• Decreased reflexes• GI concerns: ↓peristalsis
– Increased gastrin hormone secretion
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Treatment
• Parathyroidectomy is the most common treatment– May be
hypocalcemic immediately after surgery
– May need life time calcium and vitamin D replacement