NUTRACEUTICALS

Let Food be Your Medicine!!

History The Indians, Egyptians, Chinese, and Sumerians are

just a few civilizations that have used food as medicine. 

Hippocrates, considered by some to be the father of Western medicine, said that people should “Let food be thy medicine.”

The modern nutraceutical market began to develop in Japan during the 1980s. In contrast to the natural herbs and spices used as folk medicine for centuries throughout Asia, the nutraceutical industry has grown alongside the expansion and exploration of modern technology.

What is it?  Nutraceutical can be defined as “ A food or part of food

or nutrient, that provides health benefits, including the prevention and treatment of a disease.”

Nutrition Business Journal states that it uses the term nutraceutical for anything that is consumed primarily or particularly for health reasons. Based on that definition, a functional food would be a kind of nutraceutical.

The term “Nutraceutical” was coined from “Nutrition” & “Pharmaceutical” in 1989 by Stephen DeFelice, MD, Founder and Chairman of the Foundation for Innovation in Medicine (FIM).

Classification

Potential Nutraceutical - one which has promising approach

towards particular health or medicinal benefit.

Established Nutraceutical – A Potential Nutraceutical becomes

Established Nutraceutical only after there are sufficient clinical

data to demonstrate such a benefit.

Source

1. Plants - Tomato, Garlic, algae, Fruit pod

extracts

2. Animals - Shark liver oil, Cod liver oil

3. Minerals - Calcium, Magnesium, Phosphorous

4. Microorganism - Bifidobacterium, Lactobacilli

Nutraceutical may range in the form of :

Isolated nutrients,

Dietary supplements,

Genetically engineered “designer” food,

Herbal products,

Processed products such as cereals, soups,

and beverages

CATEGORIES

DIETARY SUPPLEMENTS Probiotics, Prebiotics, Antioxidants, Enzymes, etc.

HERBAL/ PHYTOCHEMICALS Herbs or Botanical products.

NUTRIENTS Vitamins, Minerals, Amino Acids, Fatty acids, etc.

Nutraceutical have the potential to play a role in healthy eating and to contribute to the prevention and treatment of diseases.

Since new molecule is difficult to discover and more expensive and risky then ever before, many pharmaceutical companies are now trying to nutraceutical so that there is undoubtedly a very huge and growing market.

The belief among consumers that these “food like substances” are either harmless or least toxic as compared to conventional pharmaceuticals.

Advantages

The role of nutraceutical in treating inappropriate dietary habits are seen as contributing to the leading cause of deaths of due to coronary heart disease, certain type of cancers etc.

Nutraceutical are gaining popularity as people are relying on them for safeguarding their health and avoiding side effects associated with drugs as well long history of use and better patient tolerance as well as public acceptance.

Plants constitute to be a major source of new lead generation of nutraceutical.

Can help cure… ^_^All therapeutic areas such as,

1. Sleeping disorders

2. Digestion problems

3. Prevention of certain cancers (Colorectal cancer)

4. Osteoporosis

5. Blood pressure

6. Cholesterol lowering (garlic)

7. Neurological disorders (Autism)

8. Diabetes etc..

DRUG

NUTRACEUTICAL

PREVENTION

Disease treatment

Health benefit

Disadvantages Not subjected to same testing and regulations as pharmaceuticals

Majority not regulated by FDA in USA

Companies creating unregulated products to create a wide profit margin

Bioavailability of nutrients is lower

No regulatory definition

Class /components source Potential benefit

Beta-carotene Carrots, various fruits Neutralizes free radicals, which may damage cells; bolsters cellular antioxidant defenses

Lycopene Tomatoes May contribute to maintenance of prostate

Mono saturated fatty acids Tree nuts May reduce risk of coronary heart disease

Flavonols Onions, apples, tea, broccoli Neutralize free radical, which may damage cells;bolster cellular,antioxidation defences

Class of Nutraceutical

Soy protein Soybeans and soy-based food May reduce risk of coronary

heart disease

Lactobacilli,

bifidobacteria

Yogurt, other dairy

and nondairy

applications

health and systematic immunity

Conclusion Nutraceutical may be beneficial to our health but

we are still learning about their benefits and

possible harmful effects.

Government regulatory bodies also face challenges

in this new category of health products, which lies

between foods and drugs.

Health professional , Nutritionists and regulatory

toxicologist should strategically work together to

plan appropriate regulation to provide ultimate

health and therapeutic benefit to mankind.

References

http://www.oilgae.com/blog/2010/09/algae-as-a-source-of-pharmaceuticals-nutraceuticals.html#sthash.QBvqUMNU.dpuf

http://www.bioline.org.br/pdf?ej06057

Brower V. “Nutraceuticals: poised for a healthy slice of the healthcare market”

Nat. Biotechnol.1998, 16, 728-731.

Raaz .M; Priyanka S; Bina R; Chauhan AK. “Healthy living with

Nutraceuticals” International Research Journal of Pharmacy 2011,2(12),12-14

Mahima ; Amit K; Ruchi T; K Karthik” Nutraceuticals from fruits and

vegetables at glance” . Journal of Biological sciences 2013,13(3):38-47

http://dravyagunatvpm.files.wordpress.com/2010/10/nutraceutical.pdf

CREDITS!!! INFO AND SOURCES

1.SAKINA M (Edited the Draft)

2.Saloni U

3.SAPNA Jain

4.Shaheen Fathima

Making of the PPT

SALMA SAYEEDEditing

Saloni U