Nucleus May13.pdf

http://www.nesacs.org

May 2013 Vol. XCI, No. 9

NORTHEASTERN SECTION • AMERICAN CHEMIC

ALSO

CIET

Y

FOUNDED 1898

NESACS

Monthly MeetingEducation Night at Tufts UniversityProfessor Thomas Gilbert, Northeastern University to Speak

Esselen Award AddressBy Michael H. Gelb and František Tureček

Cape Cod ScienceCaféBy Jack Driscoll

2013 NESACSElectionCandidate Statements

2 The Nucleus May 2013

Diseases caused by inborn errors ofmetabolism represent a diverse groupof several thousand known syndromes(1). Some affect specific organs, someare systemic, and their effects rangefrom mild that appear in adolescenceor adulthood, to severe that, ifuntreated, result in an early death ofaffected children. Inborn errors ofmetabolism are rare on an individualbasis, but their combined prevalencecan be as high as one in a few thou-sand newborns. In the past decade,breakthrough progress has been madeby U.S. pharmaceutical companies indeveloping sophisticated therapies,such as those based on enzymereplacement or erythropoietic stem celltransplantation, to treat metabolic dis-eases and save lives of affected chil-dren. The new therapies are expensiveand carry inherent risks, which placesextremely stringent criteria on diagnos-tic accuracy. Detection of inbornerrors poses specific problems, as the

disorder phenotype may not be obvi-ous in the early stages of the disease toapply the suitable therapy. Therefore,most disorders are detected by chemi-cal or bioanalytical methods usingblood samples from newborns. Eventhe use of bioanalytical methods is notwithout problems. For example, detec-tion of specific low-level proteins inblood is made difficult by interferencesfrom high-abundance blood proteinssuch as albumin. DNA analysis is ham-pered by the genetic variability ofmutations leading to the disorder.Detection of disease-specific metabo-lites can be problematic because oftheir low levels in blood and interfer-ences from other, chemically very sim-ilar, blood components. This leavesenzyme activity analysis as a powerfuland very promising chemical approachin which specific enzymes are targeted,and the lack of their activity signals ametabolic error.

The principle of enzyme activity

measurements is quite simple. A bio-logical sample from the patient is incu-bated in vitro with a synthetic substratewhich is recognized and chemicallymodified by the target enzyme. Theproduct of the enzyme-catalyzed reac-tion is then quantitatively analyzed andused to calculate the enzyme activity,which is compared to the mean activitymeasured for samples from many oth-ers, typically hundreds of individuals.If the activity is below a statisticallydetermined cutoff value, the sample isflagged for follow up genotype analy-sis to determine the DNA mutation.The analytical procedure must havefigures of merit showing good repro-ducibility, high specificity, and a verylow rate of false positives. In addition,in order to be applied in a large scaleformat of newborn screening, theenzyme activity measurements must befast and inexpensive. In our initialapproach, we used a combination ofmass spectrometry and affinity purifi-cation to develop chemical methods ofenzyme activity measurements that sat-isfied the first three figures of merit. Toimprove speed and throughput, weturned to tandem mass spectrometry todevelop new generation methods fornewborn screening of inborn errors ofmetabolism.

The diseases we have focused oncomprised lysosomal storage disorders(LSD), congenital disorders of glyco-sylation (CDG), and porphyrias. Thefirst and most important group includesdisorders affecting activities of ca. 50hydrolytic enzymes that catalyze degra-dation of biopolymers in the lysosome.CDG types I-VII are a group of disor-ders affecting activities of enzymescatalyzing carbohydrate synthesis andprotein N-glycosylation in the endo-plasmic reticulum. Porphyrias are rarediseases caused by deficient enzymesin the eight-step long biosynthesis ofthe heme that proceeds in part in thecytosol and in part in mitochondria ofliver and bone marrow cells.

Summary of the Esselen Award AddressThe New Generation Chemistry for Newborn ScreeningBy Michael H. Gelb and František Tureček, Department of Chemistry, University of Washington, Seattle

continued on page 24

The Nucleus May 2013 3

The Nucleus is published monthly, except June and August, by the Northeastern Section of the AmericanChemical Society, Inc. Forms close for advertising on the 1st of the month of the preceding issue. Textmust be received by the editor six weeks before the date of issue.Editor: Michael P. Filosa, Ph.D., ZINK Imaging, Inc., 16 Crosby Drive, Building 4G,

Bedford, MA 01730 Email: Michael.filosa(at)zink.com; Tel: 508-843-9070Associate Editors: Myron S. Simon, 20 Somerset Rd., W. Newton, MA 02465, Tel: 617-332-5273,

Sheila E Rodman, Email: serodman(at)hotmail.com, Mindy Levine, 516-697-9688, mindy.levine(at)gmail.com

Board of Publications: Mary Mahaney (Chair), Mindy Levine, Vivian K. Walworth, James PhillipsBusiness Manager: Karen Piper, 19 Mill Rd., Harvard, MA 01451, Tel: 978-456-8622Advertising Manager: Vincent J. Gale, P.O. Box 1150, Marshfield, MA 02050,

Email: Manager-vincegale(at)mboservices.net; Tel: 781-837-0424Contributing Editors: Morton Hoffman, Feature Editor; Dennis Sardella, Book Reviews Calendar Coordinator: Sheila Rodman, email: serodman(at)hotmail.comPhotographers: Morton Z. Hoffman and James PhillipsProofreaders: Donald O. Rickter, Vivian K. Walworth, Mindy Levine Webmaster: Roy HagenCopyright 2013, Northeastern Section of the American Chemical Society, Inc.

The Northeastern Section of the AmericanChemical Society, Inc.Office: Anna Singer, 12 Corcoran Road,Burlington, MA 01803(Voice or FAX) 781-272-1966.e-mail: secretary(at)nesacs.orgNESACS Homepage:http://www.NESACS.orgOfficers 2013ChairLiming Shao158South Great RoadLincoln, MA 01773limingshao(at)comcast.netshao(at)fas.harvard.edu781-518-0720Chair-ElectCatherine CostelloBoston University School of Medicine670 Albany Street, room 511Boston, MA 02118-2646Cecmsms(at)bu.eduImmediate Past ChairRuth TannerOlney Hall 415BLowell, MA 01854University of Mass LowellRuth_Tanner(at)uml.edu978-934-3662Secretary:Michael SingerSigma-Aldrich3 Strathmore Rd, Natick, MA 01360774-290-1391, michael.singer(at)sial.comTreasurer:James Piper19 Mill Rd, Harvard, MA 01451978-456-3155, piper28(at)attglobal.netAuditor:Anthony RosnerArchivistTim FrigoTrustees:Peter C. Meltzer, Esther A. H. Hopkins,Michael E. StremDirectors-at-LargeDavid Harris, Stephen Lantos, James Phillips,Ralph Scannell, Mary Burgess, John BurkeCouncilors Alternate CouncilorsTerm Ends 12/31/2013Alfred Viola Mark FroimowitzMichael Singer Sophia R. SuRobert Lichter Kenneth C. MattesMary Shultz Tim FrigoLeland L. Johnson, Jr. Mukund ChorghadeTerm Ends 12/31/2014Katherine Lee C. Jaworek-LopesMichael P. Filosa Lawrence ScottDoris Lewis Andrew ScholteMorton Z. Hoffman Raj RajurPatrick Gordon John PodobinskiMary Burgess Stuart LevyTerm Ends 12/31/2015Catherine E. Costello Marietta SchwartzRuth Tanner JerryJasinskiDorothy J. Phillips Stephen LantosMichaeline Chen Norton P. PeetJackie O’Neil Wilton Virgo

ContentsSummary of the Esselen Award Address ____________________2By Michael H. Gelb and František Tureček

Cape Cod Science Café__________________________________4By Jack Driscoll, NESACS Public Relations Chair

Monthly Meeting _______________________________________5Education Night at Tufts University, Professor Thomas Gilbert, NortheasternUniversity, and ACS District 1 Councilor to speak

Announcements ___________________________________5,6,28Truman Light 1922-2013, Nucleus to Reduce Mailing of Paper Copies, NESACSArchives Move

NEACT Central Division Meeting __________________________6

17th Annual Andrew H. Weinberg Symposium_________________7

NERM 2013 __________________________________________7

NESACS Election 2013__________________________________8Candidate Statements

NESACS at Fenway Park, May 10, 2013 ___________________12

Jerry Jasinski Receives Fulbright Grant ____________________23

Cover: Michael C. V. Jensen, M.D. speaker at the prestigious 17th AnnualAndrew H. Weinberg Symposium to be held at Dana-Farber Cancer Institute onTuesday, May 7, 2013. Dr. Jensen is the Jim and Jan Sinegal Endowed Professorof Pediatrics at the University of Washington School of Medicine and Director,Ben Towne Center for Childhood Cancer Research, Seattle Children’s ResearchInstitute. (Photo courtesy of Dr. Jensen).

Editorial Deadlines: Summer 2013 Issue: June 15, 2013September 2013 Issue: July 15, 2013

All Chairs of standingCommittees, the editor of THE NUCLEUS, and the Trustees of SectionFunds are members of theBoard of Directors. AnyCoun cilor of the American Chemical Soci-ety residing within the section area is an exofficio member of the Board of Directors.


Cape CodScienceCaféBy Jack Driscoll, NESACS Public Relations ChairThis was our sixth Science Café. Wehad several objectives: the first was toengage our NESACS members in theSoutheastern Massachusetts portion ofour territory and the second was toengage the public in interesting scien-tific topics.

We selected the Chemistry ofWine as the topic as a result of com-ments received following the success-ful Chemistry of Beer Science Café inOctober 2011. Not only did we haveNESACS members from SE MA butwe had several NESACS membersfrom NH. The local public outreachwas helped by articles in the Cape CodTimes http://www.capecodonline.com/apps/pbcs.dll/article?AID=/20121101/NEWS/211010326 , the BarnstablePatriot and the BarnstableEnterprise.

We had 80 people (2 seatings) at theCenterville Historic Museum below,but we had to close the registrationbecause of space limitations.

Shirley Corrigher, a food scienceexpert, flew in from Atlanta to lectureon wine pairing. She was joined bywine expert Diane Slater from theCape Cod Package Store. “To start, shehanded out an apple wedge, a lemonslice and a dash of salt. Then, sheinvited participants to take a bite oftheir little treat, followed by a sip ofwine.”

Sweet makes wine stronger. Lickthe lemon and take a sip. It’s milder.Sour makes wine milder. Lastly, have alittle salt and the wine becomes muchsmoother. Salt is an amazing bitternesssuppressor.

We had a number of questions

about wine making and wines fromdifferent parts of the world. Many peo-ple were asking when the next ScienceCafé was and what the topic would be.One of our NESACS members, StanHutchins, makes beer and wine athome. This was his first NESACSmeeting. He was a speaker on homebrewing at the Science Café NH inMarch 2013 http://sciencecafenh.org/index.php/2013/01/science-of-beer-and-brewing/.

Corporate Patrons $2000 - or moreAstraZeneca PharmaceuticalsEisai PharmaceuticalsEMD SeronoGenzyme Corp.Johnson MattheyMerck & Co.NovartisPfizer Inc.Schering Corp.Strem Chemicals, Inc.Vertex Pharmaceuticals$1000-$1999Boehringer IngelheimGlaxoSmithKlineIrix PharmaceuticalsLyophilization Services of NESundia MeditechYes Bank$300-$999Cambridge Major LabsGirindusMerrimack ConsultantsOrganixPCI SynthesisSigma AldrichWaters Corp.Wilmington PharmaTech


Centerville Historic Museum

Jack Driscoll co-organizer & PR chair ofNESACS- Opening the Science Café (photo byMorton Hoffman)

http://www.capecodonline.com/apps/pbcs.dll/article?AID=/20121101/NEWS/211010326

http://sciencecafenh.org/index.php/2013/01/science-of-beer-and-brewing


Monthly MeetingThe 933rd Meeting of the Northeastern Section of the AmericanChemical SocietyEducation NightThursday, May 9, 2013Tufts University51 Winthrop Street, Medford, MA

4:00 pm NESACS Board Meeting

5:00 pm Reception

6:00 pm Dinner

7:00 pm Award Meeting, Dr. Liming Shao, NESACS Chair, presiding. Lecture: Professor Thomas Gilbert, Northeastern University, ACS District 1 CouncilorTitle: Engaging Students Using Contextualized Guided Inquiry

7:45 pm Presentation of the Education Night AwardsSalutes to Excellence AwardPhilip L. Levins Memorial PrizeJames Flack Norris/Theodore William Richards Awards for Excellence in Teaching at the Secondary School LevelUndergraduate Summer Research FellowshipsUndergraduate Grants-in-AidUndergraduate Research Symposium, Phyllis Brauner Book AwardProject SEED StudentsInduction of New Members into Aula LaudisSimmons College PrizeAvery A. Ashdown Chemistry Examination Awardees

Dinner reservations should be made no later than Wednesday, May 1. UsePayPal: http://acssymposium.com/paypal.html. Select pay with credit or debitcard option and follow the additional instructions on the page. Members, $30;Non-members, $35; Retirees, $20; Students, $10. Reservations for new mem-bers and for additional information, contact the secretary Anna Singer at(781)272-1966 between 9am and 6pm or e-mail at [email protected] not cancelled at least 24 hours in advance must be paid. THE PUBLIC IS INVITEDDirections with Campus Map: http://www.tufts.edu/home/visiting_direc-tions/medford_somerville/VIA MBTA (See link above)From the West/Massachusetts Turnpike (See link above)Parking: Parking will be free after 4:00 PM in the Dowling Hall ParkingGarage at 419 Boston Avenue (within one block of 51 Winthrop Street; theevent site is on the corner of Winthrop Street and Boston Avenue) Push thevisitor’s button when entering the garage to open the gate.

Truman Light1922-2013

The Nucleus is sad to announce long-time NESACS Board Member, 1978NESACS Chair, and 1993 Henry A.Hill Award recipient, Truman S. Lightpassed away on March 26, 2013. Amore complete remembrance will bepublished in an upcoming issue. Dona-tions in his memory may be made tothe American Chemical Society or tothe Alzheimer’s Association. u

BiographyThomas R. Gilbert has a BS in chem-istry from Clarkson and a PhD in ana-lytical chemistry from MIT. After 10years with the Research Department ofthe New England Aquarium in Boston,he joined the faculty of NortheasternUniversity, where he is currently Asso-ciate Professor of Chemistry andChemical Biology. While at Northeast-ern, he has also served as the ActingDean of the School of Education andAcademic Director of graduate pro-grams in biotechnology. His researchinterests are in chemical and science

AbstractEngaging Students UsingContextualized Guided InquiryThere is nothing like a good story toget peoples’ attention. We humanshave recognized this truth since prelit-erate times when ancient storytellerscaptivated audiences with their epicpoems and tales of the feats of naturaland supernatural heroes. Lessgrandiose but still compelling accountshave conveyed insight and wisdomespecially to young audiences over thecenturies from Aesop to Dr. Seuss.

The capacity of a good story toengage one’s listeners should not belost on those of us engaged in teachingthe wonders of chemistry. In particular,the use of a good story to engage our




Chemistry andArt WorkshopDescription:We have developed a collection ofguided inquiry activities designed foruse in a Chemistry-in-Art course fornon-science majors at the college level,

although these would also be appropri-ate for use with motivated high schoolstudents. The inspiration for theseactivities was the Chemistry and Artworkshop offered by the NSF spon-sored cCWCS and begun by Dr. Patri-cia Hill of Millersville University.

The activities are based on thePOGIL (Process Oriented GuidedInquiry Learning) model, first intro-duced by faculty members at Franklin

and Marshall College and now used byover 1000 high school and college fac-ulty members to “to ensure that all stu-dents are fully engaged in the learningprocess. POGIL activities focus on coreconcepts and encourage a deep under-standing of the course material whiledeveloping higher-order thinking skills.POGIL develops process skills such ascritical thinking, problem solving, andcommunication through cooperationand reflection...” (www.pogil.org )

In addition to the benefits of thePOGIL model, which helps students todevelop their own understanding ofconcepts while working as a memberof a learning team, our activities placechemical concepts within a contextthat is appealing and interesting to stu-dents outside of the classical sciencedisciplines. We imagine that this

NEACT Central Division Meeting and Annual Meeting

Saturday, 4 May 2013Presidents’ Hall, Mazzaferro Center,Fitchburg State University

Workshop: Guided Inquiry Materials for aChemistry in Art Course

Agenda:9:30am Arrival, registration, light breakfast (coffee and

muffins/doughnuts)

10–12pm Chemistry in Art - Presentation and workshop on guidedinquiry materials for a course for non-science majors in college or an advanced high school coursePresenters: Dr. Cheryl Coolidge and Dr. Shari Litch Gray

12–1pm Light lunch (sponsored by Central Mass Section of the American Chemical Society)

1–2pm NEACT Annual Meeting

Directions: http://www.fitchburgstate.edu/about-us/directions/Parking: Ross Street Lot (#11 on Campus Map at the intersection of North St.and Ross St,http://www.fitchburgstate.edu/uploads/files/Directions/ParkingLotMap.pdfTo get to Mazzaferro Center: From the parking lot, turn left on Ross St. ,walk about 50 yards to Highland Ave. Turn right and you will soon see apedestrian plaza and Mazzaferro Center (formerly Newman Center) is a smallbuilding on your left right after the gazebo.All (including non-members) are invited.Please visit www.neact.org for more details of theorganization and how tobecome a member, if you like. Please RSVP: [email protected] Tel: 978-660-8831 (mobile) so that adequate food can be ordered. Therewill be door prizes for luckywinners! For PDP/CEU information contact:Lorraine Kelly at [email protected]

Nucleus toReduceCirculationof PaperCopiesTo close a budget gap both with theNESACS budget and The Nucleusbudget, it was decided at the AprilBoard Meeting that complimentarypaper copies would no longer be sentto the Central Massachusetts Sectionof ACS. Furthermore, new members inthe Northeastern Section would onlyreceive an email subscription to theNucleus.

IF A NEW MEMBER IN THESECTION WANTS A PAPER COPY,they will have to contact Karen Piper,Nucleus Business Manager, with arequest to be added to The Nucleusmailing list. All current NESACSmembers will continue to receive apaper copy of The Nucleus unless theysend notification to remove their namefrom the mailing list and add theiremail address to the electronic distribu-tion list. u


NERM 2013October 23-26, 2013

The 2013 Northeast Regional Meeting(NERM) will be held on October 23-26, 2013, at the Omni Hotel in NewHaven, Connecticut. The meetingwebsite is now active at<http://nerm2013.sites.acs.org/>, andshows the preliminary program with acall for abstracts for oral and posterpresentations in technical sessions(Analytical Chemistry, InorganicChemistry, Medicinal Chemistry,Organic Chemistry, Physical Chem-istry, and Undergraduate Research), aswell as for specialized symposia acrossthe spectrum of chemistry and chemi-cal education, and in nanoscience,intellectual property, entrepreneurship,art conservation, and alternative fuels.In addition, Northeast Region awardsfor volunteer service, advancing diver-sity, research achievements, excellencein high school teaching, and industrial

innovation will be presented.NERM 2013 will also be the occa-

sion for a visit to Boston and NewHaven by a delegation of twelve Ger-man graduate students and threeaccompanying persons (Dr. ElisabethKapatsina, Coordinator of Education,German Chemical Society; Anna Hof-mann, University of Konstanz, Chair,Jungchemikerforum; Prof. Alfred Flint,University of Rostock) as part of theNESACS German Exchange. Afterfour days in Boston, during which timethe group will be hosted by the North-eastern Section Younger ChemistsCommittee (NSYCC) for academicand industrial laboratory visits, culturalevents, and good, old-fashioned NewEngland gemütlichkeit, they will travelto New Haven for NERM, at whichthey will make oral and poster presen-tations about their research, and expe-rience all that a regional ACS meetinghas to offer.

At NERM, the three accompany-ing persons in the German delegation

and members of the NESACS GermanExchange Steering Committee will bejoined by ACS President Marinda Wuas speakers in a NESACS-sponsoredsymposium, “International ChemistryConnections,” that has been organizedby Morton Hoffman and Heidi Teng,members of the Steering Committee.The symposium will showcase theExchange, and will chronicle its his-tory since its origins with the first Ger-man visit in April 2001. Topics to bediscussed, among others, will includethe global initiatives of the ACS,research opportunities and chemistryeducation at all levels in Germany,development of American small chem-ical business abroad, international anddomestic NSYCC activities, and theimpact of the Exchange Program onthe evolution of participants’ careers.

Be sure to put NERM 2013 onyour calendar, bookmark its website,consider submitting an abstract, anddefinitely attend. See you in NewHaven! u


The 17th Annual Andrew H. Weinberg

SymposiumMichael C. V. Jensen, MD

Jim and Jan Sinegal Endowed Professor of Pediatrics, University of Washington School of Medicine

Director, Ben Towne Center for Childhood Cancer Research, Seattle Children’s Research Institute

Enhancing the IQ of Chimeric Antigen ReceptorRedirected T cells for Cancer Immunotherapy

Tuesday, May 7, 20134:00 pm – 5:00 pm

Yawkey 306Dana-Farber Cancer Institute,

35 Binney St, Boston, MA, 02115Contact: Sarah Hagan,

[email protected], Tel: 617-632-4580

BiographyMichael Jensen, MD, is a renownedpediatric cancer researcher. He joinedSeattle Children’s in 2010 after spend-ing 13 years at City of Hope, where hewas director of the Pediatric CancerProgram and co-leader of the CancerImmunotherapeutics and TumorImmunology department. Jensen haswritten more than 50 research papers,won two Young Investigator Awards,and received more than $2 million inresearch funding from the NationalInstitutes of Health. At City of Hope,he conducted the first FDA authorizedtrial of T-cell therapies for childrenwith recurrent neuroblastoma. He wastrained at the University of Pennsylva-nia School of Medicine and completeda fellowship in pediatric hematology-oncology at the University of Washing-ton and the Fred Hutchinson CancerResearch Center. He received his B.S.degree in biology from Tufts Univer-sity. u


Chair-ElectKatherine L. Lee

Education: B. S. Chemistry, summacum laude, with Distinction in Chem-istry, 1991, Yale University; Ph. D. inOrganic Chemistry, 1996, Massachu-setts Institute of Technology (R.L. Dan-heiser); Postdoctoral Fellow,1996-1998, University of Texas atAustin (S.F. Martin).

Professional Experience: MedicinalChemist: Mitotix Inc. (now Agennix),1998-2000; Wyeth Research, 2000-2009; Pfizer Inc., 2009-present. Currentposition: Associate Research Fellow,Worldwide Medicinal Chemistry, PfizerInc., Cambridge, MA.

Honors/Professional Activity:Department of Defense, Office ofNaval Research Predoctoral Fellowship,1991-1994; MIT Department of Chem-istry Teaching Award, 1995; WyethTeam of the Year Award (to projectteam), 2001; Wyeth-MIT Lecture Com-mittee, 2003-2006; Pfizer BioTherapeu-tics Chemistry Team of the Year Award(to project team), 2011; Mentor inHealthcare Businesswomen’s Associa-tion, Boston Chapter, 2009-2010.

ACS Service: Member of Organicand Medicinal Chemistry Divisions ofthe ACS; Chair, Northeastern SectionHost Local Section Committee, 2009-2010; Member of Northeastern SectionSymposium Committee, 2009, 2010;Councilor, Northeastern Section, 2012-present; Member-at-Large, Division ofOrganic Chemistry Executive Commit-tee, 2011-present.

Position Statement: It would be anhonor to serve as Chair-Elect toNESACS. If elected, I would bring myexpertise as a scientist, leader, and well-

connected collaborator to the leadershipof our section.• Scientific Impact

I have had the pleasure to work withmembers of our local section toorganize the 2010 Advances in Chem-ical Sciences Symposium, focusingon medicinal chemistry and organicsynthesis; and the 2009 and 2010Advances in Chemical Sciences:From Bench to Pilot Plant Symposia,focusing on synthetic methodologyand process chemistry. The symposiafeatured speakers from industry, aca-demia, and government, and broughtchemists together to share hot sci-ence, check out new technology andservices from vendors, and providedscientists the opportunity to network.My contributions included helping tobuild the scientific agenda, fund-rais-ing, publicity, and inviting and host-ing speakers.

Since 2012, I have been servingas a Councilor for the NortheasternSection, and have helped to shape thescientific agenda for our section’sactivities by recommending speakersfor NESACS symposia, and, by join-ing forces with members of NESACSand my colleagues in the BioThera-peutics Chemistry group at Pfizer,hosting Nobel Laureate ProfessorOsamu Shimomura at the January2012 NESACS meeting at our Pfizersite in Cambridge, MA.

Moving forward, as Chair-Elect,I would advocate for NESACS tocontinue to promote cutting-edge sci-ence through our selection of speak-ers for monthly meetings and indesigning the symposia we sponsor.

• LeadershipIn 2010, I chaired the Host Local Sec-tion Committee. The mission of ourband of NESACS volunteers was toprovide information and hospitality tovisitors at the 2010 Fall National ACSMeeting in Boston. We penned arti-cles for The Nucleus on gettingaround Boston and recommending“hidden gem” restaurants, and more;distributed thousands of copies of TheNucleus at the meeting; recruited stu-dents to assist ACS staff; and manned

a NESACS booth and helped answerall sorts of questions posed to us bymeeting attendees.

Indeed, if I became Chair-Elect, Iwould parlay my experience leadingthis committee in 2010 to making the2015 ACS National Meeting inBoston another success in terms ofthe contributions of NESACS. Morebroadly, I would work hard to recruitnew volunteers to join the dedicatedleaders in NESACS, to become activemembers of NESACS and getinvolved in our diverse NESACS ini-tiatives.

• Collaboration Having worked in the biotech andpharma industry for close to 15 yearsin a team-based environment, andmore recently, through my work as avolunteer both in this section and inthe ACS Division of Organic Chem-istry, for which I serve as a Member-at-Large of the Executive Committee,I recognize the value of networkingand collaboration. Recently, I helpedto recruit distinguished scientists forthe Esselen Award Canvassing Com-mittee by calling upon people withwhom I had worked in the past. Asthe co-chair of the DOC SummerUndergraduate Research Fellowshipand the DOC Technical Achievementsin Organic Chemistry committees, Iworked with volunteer committeemembers from across the country toraise funds and administer these pro-grams.

If elected, I would foster thisspirit in the work of NESACS, forexample, to help our members navi-gate career changes; to encourageNESACS members to build their net-works by attending NESACS-spon-sored events such as Science Cafés,Younger Chemist Committee pro-grams and Medicinal Chemistry sym-posia; and for budding scientists, tobring greater engagement in programssuch as STEM in which NESACS canhelp promote K-12 education in sci-ence, technology, engineering andmathematics. Thank you for your consideration.

NESACS Election 2013

James Phillips

Education: I received my M.S.degree in Inorganic Chemistry fromUniversity of Cincinnati and B.S.degree from Tennessee State Universityin Nashville, Tennessee.

Professional Experience: My careerpath includes the following companiesand positions: Research Chemist atSheppard Chemical Company in Nor-wood, Ohio; Technical Service Engineerat the Dow Chemical Company in Mid-land, Michigan: Chemical Supervisor atCorning Medical in Medfield, MA;Laboratory Supervisor at Muro Pharma-ceutical Company in Tewksbury, MA.Currently I am a Technical ServiceEngineer with Waters Corporation inMilford, MA.

Position Statement: I am honored tobe a candidate for Chair-Elect of ourgreat and renowned Northeastern Sec-tion (NESACS). If elected, I will do mybest to help make the section evenstronger. I am a member of the Boardof Publications and working with myfellow members to enhance its opera-tions. I have been the Photographer formany of the Section meetings.

If I am elected to the position ofChair-Elect I would like to focus onincreasing the involvement of youngchemists in NESACS activities. In addi-tion, I would strive to develop NESACSprograms that attract more speakers andattendees from industry and the generalpublic while maintaining the involve-ment of scientists from academia. Iwould appreciate your vote for Chair-Elect of NESACS.

Councilor/AlternateMichael Singer

Education: B.S., State University ofNew York at Stony Brook (1986); M.S.,Brandeis University (1988); Ph.D.,Brandeis University (1993)

Professional Experience: Post-Doc-toral Research Associate, Organix Inc.1991-1994; Senior Scientist, ArQuleInc. 1994-1996; Group Leader, Auto-mated Combinatorial Synthesis, ArQuleInc. 1996-2001; Group Leader, DrugDiscovery Research and Development,Sigma-Aldrich, Natick, 2001-2007;R&D Manager, Sigma Aldrich, Natick.2008-Present

NESACS Service: Councilor-NESACS 1996-2001, 2005-present;Alternate Councilor – NESACS 2002-2004; Board of Directors NESACS1993-present; Secretary-NESACS1998-present; Medicinal ChemistryGroup (MCG) 1991-2002; MCG Treas-urer (1992-1993), Program Chair (1994)Chair (1995-1996)

ACS Service: ACS Joint Board-Council Committee on ChemicalAbstracts Service; Associate member2004; Member 2005-2007. Local Sec-tion Activities Committee; AssociateMember 2007; Member 2008 - present

Professional Recognition: HenryHill Award – 2008

Position Statement: The Northeast-ern Section of the American ChemicalSociety has over 7000 members. Ourcollective voice needs to be heard. Dur-ing my tenure as Councilor and Alter-nate Councilor for the NESACS I havehad the opportunity to bring that voicedirectly to the attention of the nationalofficers of the American Chemical Soci-ety. Maintaining open communicationbetween the local and national officersof the ACS is critical to the growth ofour professional organization.

For the past 6 years I have been amember of the Local Section ActivitiesCommittee. I have learned a great dealabout how our very large local sectionfits into the world of the AmericanChemical Society and actively workingwith ACS resources to identify how toenrich the member experience here inthe Northeastern section.

As your local elected representativeto the National ACS Council I would

hope that you would contact me withany concerns and issues([email protected]) so I maydirect them to the appropriate offices ofthe ACS. With your support and vote Ipledge to continue to work as a voicefor the local membership.

Leland L. Johnson, Jr.Education: Virginia Tech, B.S.,

1993; Virginia Commonwealth Univer-sity, M.S. 2003; Boston University,M.A. 2008

Professional Experience: ConditasBiotechnology Group, LLC, Founderand Principal, 2010-present; CreaGenBiosciences, Business DevelopmentManager, 2009-2010; Novartis Institutesfor Biomedical Research, ScientificAssociate II, GDC-Ophthalmology,


In the interest of providing maximuminformation and expression of opinionby the candidates for election in 2010,the Nominating Committee has pre -pared this section of the NUCLEUSfor mailing concurrently with the bal-lots. All candidates were asked to sub-mit biographical material and, with theexception of committee member nomi -nees, position statements. To attainuni formity of format, the biographicaldata have been rearranged, and, wherethe text exceeded the allotted space,abbre viated. The statements have beenrepro duced without change. An officialballot, along with a ballot envelopeand return envelope have been pro-vided. The election and balloting arebeing carried out in conformance withArticle VIII of the Constitution of theNorth eastern Section. The order ofcandidates for each office on the ballotwill be determined by lot. Commentsregarding the election may beaddressed to the Nominating Commit-tee Chair, Ruth Tanner (address on p.3).The ballot must be received by May31, 2013 u

NESACSElectionElection of Candidates


2008-2009; Adenosine Therapeutics,LLC, Senior Research Associate, A2AProgram, 2002-2003; Insmed Pharma-ceuticals, Research Associate, Discoveryand Development, Diabetes, 1999-2002.

Honors/Awards: Member, AlphaChi Sigma-Gamma Iota (1990); Chem-luminary Award to NSYCC, Outstand-ing or Creative Local Section YoungerChemists Committee Event 2007; Member, German Exchange, 2006, toKonstanz; Top Ten Poster, JCF-Fruehjahr ssymposium, Konstanz, Ger-many 2006.

Service in NESACS/NSYCCoffices: Councilor, 2011-Present,Fundraising Committee Member, 2013-Present, Public Relations Chair, 2009-2011; YCC Chair, 2008-2009; YCCCareer Chair, 2007-2008; OrganizedNovartis/NESACS Town Hall Forum,FEB-2010, Organized Schlumberger/NESACS /Henry A. Hill Award Meet-ing, OCT-2011.

Position Statement: It has been anhonor to work within the ACS frame-work as Councilor from and forNESACS. The Council functions as asort of “House of Representatives” forcertain issues before the ACS. Travelingto National Meetings for Council and

for international scientific exchange aswell as networking has been, and con-tinues to be, an excellent way to engagechemists from across the nation andthroughout the world.

For the past ten years, I have had theprivilege of building my chemistrycareer and business career within oursection. The Boston area has some ofthe most intelligent, creative and entre-preneurial chemists, scientists and busi-ness professionals that I have ever met.If re-elected as Councilor, I will con-tinue to connect with our members atmonthly meetings and many otherevents in order to understand the con-cerns and needs of our colleagues acrossthe many fields of chemistry. I take theresponsibility of representing NESACSand your interests very seriously.

One focus that I will have if re-elected as Councilor is to follow thegreat examples of leadership within oursection. These leaders have developedactivities for the next generation ofchemists, the younger chemists, fromgrade school to graduate school and intotheir careers. Volunteers have initiatedand supported programs like the Ger-man Exchange, the Younger ChemistsCommittee, and ACS Scholars in order

to help younger chemists integrate intoour profession more smoothly withcompetitive advantages and realisticexpectations.

Looking back, I had the distincthonor of selection to the Boston-basedgroup travelling to Konstanz, Germanyin spring 2006 for the NESACS-GDChExchange Program. Following my par-ticipation in the exchange program, Ibegan my formal service to our section.As YCC Career Chair in 2007, I workedwith students from BU, UMass Bostonand Tufts to execute the Northeast Stu-dent Chemistry Career Fair (2007) thatreceived national recognition from theACS in the form of a Chemluminaryaward. This was a real initiation into theway corporations, academia, and indi-viduals can work together to advancethe careers of younger chemists.

Since then, I have worked withinNESACS as Public Relations Chair,continuing a mission of outreach for thechemists in the section and beyond,sometimes using social media outlets.As you may already know, NESACShas a fast growing and informativeLinkedIn page. Working with a previoussection chair, the current secretary, andthe expanding professional networks ofour current PR Committee, we createdthe NESACS LinkedIn page that nowreaches thousands of chemists directly.Additionally, personal involvement inorganizing successful, corporate-spon-sored monthly NESACS meetings hasincreased public and corporate aware-ness of our section.

I will continually strive to promoteprojects and programs that have a broadand positive impact for our section andour members. I look forward to speakingwith you at the next monthly meeting,NESACS event, or other networkingopportunity about comments and con-cerns you have, and the issues you face.

Mary Jane ShultzEducation: B.S. with Honors, Uni-

versity of Wisconsin; Kansas State Uni-versity; Ph.D. in Theoretical PhysicalChemistry, Massachusetts Institute ofTechnology.

Professional Experience: Professor,Tufts University, (1999-to date); Chair,Department of Chemistry, Tufts Univer-sity (2000-2006); Research Scientist,

Laser Spectroscopy Laboratory, M.I.T.,(1985-89); Associate Professor, TuftsUniversity (1985-1999); Visiting Pro-fessor, M.I.T. (1985-87); Assistant Pro-fessor, Tufts University (1979-85);Research Fellow, Brandeis University(1979-80); Assistant Professor, Univer-sity of Massachusetts, Boston (1978-79); Research Associate/Lecturer,Boston College (1977-78); RadcliffeFellow, Radcliffe College (1976-1977);Research Fellow, Harvard University(1976-77); Post-Doctoral ResearchAssociate, University of California,Berkeley (1975-76).

NESACS Service: Councilor, North-eastern Section American ChemicalSociety; James Flack Norris AwardCommittee (12 years, Chair threetimes); Local coordinator for EducationNight; Northeastern Section ACS Pro-gramming Committee.

National ACS member since 1972;Women Chemists Committee; ChairRising Star Award Committee; Coun-cilor, Alternate Councilor, PhysicalChemistry Division; Representative ofthe Physical Chemistry Division at theMultidisciplinary Program PlanningGroup; Physical Chemistry Poster Ses-sion Judge (three times).

Membership/Honors: AAAS Fel-low; One of six US representatives to theInternational Congress: Chemical Sci-ences and Society, Kloster Seeon, Ger-many; Outstanding Faculty Award, TuftsUniversity (Chemistry); National Sci-ence Foundation Visiting Professorship;Mellon Grant Faculty DevelopmentAward; Brandeis University ResearchFellow; Research Fellow, Division ofEngineering and Applied Physics, Har-vard University; Radcliffe Fellow, Rad-cliffe Institute; Greenlaw Fellow, M.I.T.;Honors Graduate, U. of Wisconsin.Memberships: American ChemicalSociety; Divisions Physical Chemistry,Colloid and Surface, Chemical Educa-tion, Environmental Chemistry; Ameri-can Association for the Advancement ofScience; American Physical Society;Sigma Xi; Iota Sigma Pi (ISP)

Position Statement: The AmericanChemical Society is facing an interest-ing time; a time when increasing global-ization brings opportunities along withchallenges. Additionally, the economictimes demand technical solutions. I amhonored to have represented the North-

eastern section’s interests as a Coun-cilor, during the dialog concerninggreater inclusion of International mem-bers as well as members of sister soci-eties in our meetings. The global reachof chemistry and chemical education isreflected in selection of internationalwinners of the James Flack NorrisAward for Outstanding Achievement inthe Teaching of Chemistry. Promotionof educational activities is one of mymajor interests; chairing the NorrisAward Committee three times. On thenational level, I have co-chaired severalsymposia as well as serving as a judgeof the excellent graduate student posterspresented at the meeting.

Throughout my career, I have contin-uously been impressed at the greaterrichness that results from greater inclu-sion. To promote inclusion, I amdelighted to have been appointed byPresident Shakhashiri to the nationalWomen Chemists Committee. As part ofthat committee, I have been activelyinvolved in development of the RisingStar Award for mid-career women. Theaward is unique in that it specificallyrecognizes women in industry and gov-ernment positions as well as those inacademic institutions large and small.

As a Councilor, I am also a memberof the NESACS Board. The Northeast-ern Section is one of the largest in thesociety; we host the annual meetingperiodically and have an active andaccomplished membership. I am hon-ored to be selected to run for councilor;vote for me and I will continue to repre-sent our interests both at the local andNational levels.

Robert L. LichterNortheastern Section, Merrimack

Consultants, LLC, Great Barrington,MA.

Academic Record: Harvard Univer-sity, A.B. cum laude, 1962; Universityof Wisconsin, Ph.D., 1967.

Honors: Recipient, ACS Award forEncouraging Disadvantaged Studentsinto Careers in the Chemical Sciences,2010; Fellow, American Chemical Soci-ety, 2009; Fellow, American Associationfor the Advancement of Science, 1995;Fellow, Association for Women in Sci-ence, 2004; American Council on Edu-cation Leadership Training Fellowship,1983; National Science Foundation Sci-ence Faculty Professional DevelopmentAward, 1981; National Research Coun-



cil Travel Awards, 1975, 1977; NationalInstitutes of Health Postdoctoral Fellow-ship, 1967-68; National Institutes ofHealth Predoctoral Fellowships, 1962-66.

Professional Positions (for pastten years): Principal and Co-founder,Merrimack Consultants, LLC, 2002 todate; Executive Director, The Camilleand Henry Dreyfus Foundation, Inc.,1989-02.

Service in ACS National Offices:Committee on Science, 1997-02, Com-mittee Associate, 1996, Consultant,2003; Committee on Minority Affairs,1999-06, Committee Associate, 1997-98, ACS Scholars Program Subcommit-tee, 1998-2008; Committee on Budgetand Finance, 2006-present, CommitteeAssociate, 2005, Vice Chair 2009, Sub-committee on Program FundingRequests, 2006-present, Chair, 2008-present, B&F Advisory Committee,2005-2006, 2008-present; AdvisoryBoard, Chemical & Engineering News,1998-06; Chair, ACS Board of Directorsad hoc Implementation Project onMinorities in Academia, 2003-06; ACSDevelopment Advisory Board, 2008-present; Canvassing Committee, ACSAward for Research in an Undergradu-ate Institution, 1997-99, Chair, 1999;Graduate Education Advisory Board,2002-2006; ACS Board Task Force onPercy Julian, 2006-present

Service in ACS Offices: MemberACS since 1962. Northeastern Section:Chair, NESACS Planning Committee forFall 2007 National ACS Meeting, 2006-

2007; Chair, NESACS ACS ScholarsCommittee; Councilor, NESACS, 2008-2013; Georgia Section: Chair-Elect,2004; Chair, 2005. North Jersey Sec-tion: Analytical NMR Topical Group,Chair, 1982-83. Member: AmericanAssociation for the Advancement ofScience; Association for Women in Sci-ence, ACS Divisions: Organic Chem-istry; Chemical Education.

Related Activities: American Associ-ation for the Advancement of Science,Section on Chemistry: Chair-Elect,2000-01, Chair, 2001-02, RetiringChair, 2002-03, Secretary, 2004-09;Association for Women in Science:member, AWIS Fellows Selection Com-mittee, 2006-2007, Chair, 2007; SigmaXi: Public Understanding of ScienceCommittee, 2004-2005; New YorkAcademy of Sciences: Committee onScience Education, 1991-95, Vice Chair,1993-94, Chair, 1994-95; National Con-ferences on Undergraduate Research:Board of Governors, 1992-98, Chair,1994-96; Gordon Research Conferenceon Innovations in College ChemistryTeaching (now called Chemical Educa-tion Research and Practice): Vice Chair,June 1999, Chair, January 2001;National Research Council ChemicalSciences Roundtable: 1996-2000, Steer-ing Committee, 1996-99; NSF Commit-tee on Equal Opportunities in Scienceand Engineering: member, 2003-08,Vice Chair, 2004, Chair, 2005; NSFAdvisory Committee on EnvironmentalResearch and Education: member, 2003-06; NSF Advisory Committee on GPRA

Performance Assessment: member,2006-2008; NSF Committee of Visi-tors, National STEM Digital Library,2005; NSF Senior Scientist Consultant,2009; Chair, Board of Governors, Mas-sachusetts Academy of Sciences, 2009;New York Hall of Science: member,Board of Trustees Advisory Council,1994-96, 1998-2002; member or chairof >15 external advisory or visitingcommittees on behalf of academic insti-tutions, the National Science Founda-tion, and other organizations; memberof >20 review panels for NSF, NationalInstitutes of Health, National ResearchCouncil; Magnetic Resonance in Chem-istry, editorial board, 1983-87; Conceptsin Magnetic Resonance, Editor, 1989-94; State University of New York atStony Brook, Vice Provost for Researchand Graduate Studies, 1986-89;Research Corporation, Program Officer,1983-86; Sandoz Pharmaceutical,Exxon Research and Engineering Co.,Visiting Scientist, 1981-82; Experimen-tal NMR Conferences, Inc., ExecutiveCommittee, 1979-85, Treasurer, 1981-85; Hunter College of the City Univer-sity of New York, ChemistryDepartment, Assistant Professor, Asso-ciate Professor, Professor, 1970-83,Department Chair, 1977-82; CaliforniaInstitute of Technology, Research Asso-ciate, 1968-70; Technische HochschuleBraunschweig, Germany, NIH Postdoc-toral Fellow, 1967-68; Research publi-cations: 38 research articles, threebooks, one book chapter; Other publica-tions: many articles and book chapterson education and policy.

Position Statement: I am honored tobe nominated for reelection to a thirdterm as a NESACS ACS Councilor. Oneof the oldest and now the largest of theLocal Sections, in a location whoseintellectual and professional strength isexceeded by none, NESACS deserves acontinuing leadership role in ACS. Asan active ACS member for 51 years,your Councilor for six, and a participantin numerous ACS committees and othernational activities detailed on my biog-raphical sketch, I understand very wellhow ACS functions.

As your Councilor, I continued toserve as a Councilor on the SocietyCommittee on Budget and Finance(B&F), including two terms as ViceChair, a member of both the B&F Advi-

ACS Northeastern Section at Fenway Park!

Red Sox Game 7:10pm, Friday, May 10thIn the return of a popular NESACStradition, NESACS members, andfriends of NESACS are invited toFenway Park on Friday, May 10th towatch the Red Sox play the TorontoBlue Jays. Our right field grandstandseats are priced at $35 and includehandling charges.

These tickets will go fast! Reserve your seats by mailing yourcheck (payable to NESACS) to AnnaSinger, 12 Corcoran Road, Burling-ton, MA 01803. Questions (but not reservations) maybe sent to [email protected]. u

sory Subcommittee and the ProgramReview Advisory Group (PRAG), andChair of the Program Funding Request(PFR) subcommittee. ACS has survivedthe economic recession, in large partbecause B&F, PRAG, and PFRapproached its responsibilities with theultimate in serious reflection to establisheffective cost-saving measures withoutcompromising ACS’s mission and goals.Most recently, in my role as PFR Sub-committee Chair, I am collaboratingwith a Board Working Group that isdeveloping approaches to shaping andassessing the impact of ACS’s portfolioof programs. As your Councilor, I amprivileged to be part of those processes.I also serve on the ACS DevelopmentAdvisory Board, which advises the ACSDevelopment Office on fundraisingstrategies; and continue to be involvedwith the ACS Scholars Program.

For the future, I continue to be con-vinced that developing the next genera-tion of chemists is of paramountimportance to all of us. My own experi-ence, that of others, and some researchevidence reinforces the notion that stu-dent participation in actual research atthe earliest possible stages is one of themost effective ways to attract new peo-ple into the chemical sciences. I con-tinue to work toward having ACS createor at least facilitate these opportunitiesfor pre-college students, undergraduatesin two- and four-year colleges, and mid-dle and high school teachers. Throughthe PFR responsibilities, I have helpedshape the ACS GREET program, whichaffords research opportunities abroad toundergraduates and their research advi-sors.

Finally, although the chemical work-force and its leadership comprise peopleat all degree levels, advanced degreesare still required for many positions.Because graduate (especially doctoral)education is more than research training,graduate students need to learn a varietyof skills, including those in manage-ment, communication, and business, ifthey are going to exploit the array ofcareer opportunities open to them in achanging and global economy, and even-tually move into leadership positions.ACS has a leadership role to play in thisarena; the ACS Leadership Develop-ment program continues to show greatpromise in fulfilling that role. For all

these reasons, and more, I look forwardto continuing to serve you as a Coun-cilor, and welcome your support.

Sophia R. SuEducation: The Ohio State Univer-

sity, Ph.D. in Organometallic Chemistry.Professional Experience:

• Optical – Enterprise, INC., Marlboro,Ma., Senior Scientist, 2006-2008

• Polaroid Corporation, Norwood,Ma., Senior Scientist, 1993-2005

• GTE Laboratories, Waltham, Ma,Principal Member of Technical Staff,1976-1992

• Chemistry Department, Harvard Uni-versity, Cambridge, Ma., ResearchAssociate 1975-1976

• Brooklyn College, Brooklyn, N.Y.,Adjunct Assistant Professor/ ResearchAssociate 1973-1975

• California State University at Fuller-ton, Lecturer and Research Associate1972-1973 Achievements: Hold 19 U.S. patents,

1 Polaroid trade secret in the fields ofsuperconductor processing, Sol-Gelcoating processing, hydro-metallurgicalextraction process, CVD coatingprocess and sun-glasses fabrication.

Published 35 papers in the fields oforganometallic chemistry, surface chem-istry, graphite- intercalation, synthesisof polymer-precursors for silicon-nitrideand silicon- carbide.

Membership: Member of ACS for45 years; Alternate Councilor ofNESACS for three terms

Statements:• Promoting inter-disciplinary interac-

tions among material scientists,chemists, biologists by organizing fre-quent discussion groups.

• Promoting interactions among localyoung chemists, small business entre-preneurs to foster their career path.

• Acting as a mentor in science fairs forlocal schools and as a volunteer totutor local students for their sciencecourses.

• Organizing summer outings or activi-ties to promote science to local highschools or community college stu-dents.

• Organizing volunteers to demonstratescientific subjects to students fromelementary to high schools in scienceor children museums during schoolvacation weeks and chemistry week.Position Statement: I do believe that

we should cultivate students’ scientific



interests and enhance their scientificcurriculum to be leaders in the 21st cen-tury. With my academic and industrialexperience, I am the best person to servethis community. If I am elected, I willdevote my energy and time to accom-plish these goals.

Kenneth C. MattesEducation: University of Wisconsin

School of Pharmacy, Madison, WI,1974-75• Postdoctoral work with Dr. C.R.

Hutchinson• Synthesis of indole alkaloids, iridoids,

and antitumor agents. Determined thebiomimetic mechanism of Camp-tothecin biosynthesis.

Iowa State University, Ames, IA, 1972-1974, Ph.D. in Organic Chemistry withDr. Orville ChapmanIowa State University, Ames, IA, 1969-1972, MS in Organic Chemistry withDr. Glenn Russell. University of Illinoisat Chicago, Chicago, IL, 1965-1969;BA in Chemistry.

Professional Experience:• ASTRA-ZENECA, Waltham, MA

02451 (2000-Present)• ASTRA-ZENECA, Worcester, MA

01605 (1999-2000)• ASTRA-ARCUS USA, Worcester,

MA 01605 (1998-1999)• EASTMAN KODAK COMPANY,

Rochester, NY 14650 (1976-1998)ACS Service: Northeastern Section,

Alternate Councilor, 2010 to 2013.National ACS, Local Section ActivitiesCommittee, 1996-1998. Rochester Sec-tion Councilor, 1995-1998. RochesterSection: Creator and Chairman, Sci-ence Saturdays at RMSC (1994-1998).Rochester Section, Past-chairman 1994.Rochester Section, Chairman 1993.Rochester Section, Chairman-elect1992. Rochester Section, ROCi/ACSGolf Tournament Chairman, 1993-1998

Rochester Section Committees:National Chemistry Week, 1990-1998;Publicity, 1990-91; Long Range Plan-ning, 1992-94; Nominations and Elec-tions, 1993; Harrison Howe, 1993;Professional Relations, 1993-94;Finance, 1994, Minority Affairs, 1997;

Rochester Section, Member-at-large(1990-91) Medicinal Chemistry SectionOrganic Chemistry Section Agrochemi-cal Section

ACS Speaker Service: Inside Storyof Color Photography (1977-1998), over100 invited lectures. AICHE SpeakerService: Inside Story of Color Photogra-phy (1980-1998), over 20 invited lec-tures.

Relevant Memberships:• Boston Area Group for Informatics

and Modeling • American Chemical Society• American Association for the

Advancement of Science• International QSAR and Molecular

Modeling SocietyHonors: Massachusetts State Referee

Committee, Soccer Referee Instructor ofthe Year, 2008. Rochester SectionAward Recipient, 1995. Phoenix AwardWinner , ROCi/ACS National Chem-istry Week, Malls Chairman, 1990-91

Position Statement: If elected to theposition of councilor for NESACS, Iwould strive to represent at the nationallevel those issues of most importance toNESACS. I would also strive to supportthe changes and challenges faced by theAmerican Chemical Society to raise theimage of chemistry and stress theimportance of chemistry to solve theproblems of the future.

Specific goals would be to supportthe Local Section Activities Committeeprograms, recommend a program toaddress the informtion managementissues assoiated with Local SectionsArchive materials using the capabilitiesof History of Chemistry, Computers inChemistry and CINF divisions, and con-tribute to the National Chemistry Weekprogram. As scientific and professionalproblem solvers, members of the ACSneed to help improve the educationaland professional opportunities affordedby one of the largest professional soci-eties.

Mary A. MahaneyEducation: B.A .Emmanuel College

(1971); M.S. Northeastern University(1973); Dr. rer. nat. University of Con-stance, Germany (1977); M.B.A.Worcester Polytechnic Institute (1996)

Professional Experience: HaartzCorporation (1999 – present); PolaroidCorporation (1982 - 1998); Universityof Zurich, Switzerland (1979 - 1981);University of Constance, Germany(1977 - 1979)

NESACS Service: Member since1977. Continuing Education Committee(1998 - 2008); Richards Medal Commit-tee (2000 – 2004); Alternate Councilor(2005-2007); Board of Publications(2004 – present)

Position Statement: I would appreci-ate the opportunity to support our sec-tion as a councilor. In this capacity, Iwill consistently keep the interests ofour NESACS members before theNational Council.

Raj RajurEducation: Ph.D. in Organic/Medici-

nal Chemistry, Karnataka University,Dharwad, India (1988); PostdoctoralFellow, University of Texas Southwest-ern Medical Center, Dallas (1988-1990);Group Leader, Boston College, Chest-nut Hill, MA (1990-1992); Instructor,Center for Engineering in Medicine,Massachusetts General Hospital, Har-vard Medical School (1992-1996).

Professional Experience: Instructor,Shriner’s Burns Institute, Boston;Instructor, Massachusetts General Hos-pital, Harvard Medical School; AdjunctAssistant Professor, Northeastern Uni-versity, Boston; Group Leader, Milli-pore Corporation, Bedford, MA; ProjectLeader, ArQule, Inc., Woburn, MA.Reviewer, Journal of PharmaceuticalSciences (ACS Journal); Recipient ofresearch grants from University ofTexas Southwestern Medical Center,Dallas. Presently, Founder (2002),Chairman and CEO of CreaGen Bio-sciences, Inc., Woburn, MA.

ACS/NESACS Service: AlternateCouncilor, NESACS (2005-present);Program Chair, Medicinal ChemistryDivision, NESACS (2003-present);NESACS Nominating Committee(2008); Organizing Committee,NESACS, IUPAC and RSC-US-Spon-sored Advances in Chemical SciencesSymposium Series (2007-present).

Memberships/Honors: ACSOrganic Chemistry Division, ACSMedicinal Chemistry Division AAAS,and Indian Chemical Society. Listed inAmerican Men and Women of Scienceand Who’s Who in Science and Engi-neering. Involved in many Indian cul-tural and community organizations onadvisory boards. Invited speaker at sev-eral international conferences.

Position Statement: In my tenure asprogram coordinator and program chairfor the NESACS Medicinal ChemistryDivision, my mission has been to bringquality drug discovery science to ourMay, September and December annualsymposia. Some of the recent topics onwhich we have focused are Kinase Tar-gets, New Targets for Type-2 DiabetesParts I and II, New Trends in OncologyParts I and II, Signal Transduction Tar-gets and Drug Discovery, New Devel-opments in Ant-Infective Research,Lead Optimization Strategies, NewTechnologies for Drug Discovery, andEmerging Opportunities for Drug Dis-covery in Asia. The purpose of bringinggood pharmaceutical science to our veryactive local section audiences is multi-purpose. Our territory now houses thebiotech hub of the world, and hasbecome a location where every multina-tional pharmaceutical company wants topartner, headquarter or establish a Centerof Excellence. We, as a section, need tobe exposed to a cross section of the sci-ence that is ongoing in the industry. Ourmeetings are venues for the exchange ofideas between industrial and academicparticipants. And, very importantly, ourmeetings are places where students fromour many prestigious colleges and uni-versities can network with professionalsand learn from the symposia topics fea-turing cutting edge science.

As an Alternate Councilor, I haveregularly attended the NESACSmonthly meetings and contributed sev-eral new ideas and inputs. I have regu-larly represented NESACS at nationalACS meetings and participated in gov-ernance meetings.

If elected as a Councilor, I will con-tinue to support and encourageNESACS meetings that bring topnotchscience to our audiences of academicand industrial professionals and stu-dents. I also plan on initiating the estab-lishment of Medicinal chemistry prizeand exchange program with Indian uni-versities similar to German Exchangeprogram. I ask for your vote and thankyou for your support.

Andrew ScholteEducation: B. Sc. (Biochemistry; 1st

Class Honors) Simon Fraser University,2000; Ph.D. (Chemistry) University of

Alberta, 2006; Professional Experience: Genzyme,

a Sanofi Company, Medicinal Chem-istry Department, Staff Scientist II,2012-present; Genzyme, a Sanofi Com-pany, Medicinal Chemistry Department,Staff Scientist I, 2008-2012; BostonCollege, Chemistry Department,NSERC Postdoctoral fellow with Prof.Marc Snapper, 2006-2008.

Honors/Awards: ACS LeadershipDevelopment Award (2010); NaturalSciences and Engineering ResearchCouncil of Canada (NSERC) PDF(2006-2008); Outstanding Oral Presen-tation-Canadian Society for Chemistry(2005); Canada Graduate Scholarship(2003-2005); NSERC PostgraduateScholarship A (2001-2003); AlbertaHeritage Studentship (2000-2005); Fac-ulty of Science Graduate EntranceScholarship (2000); Department ofChemistry Entrance Scholarship (2000);Walter H. John Scholarship (2001-2005); Mary Louise Imrie Graduate Stu-dent Award (2004); Alfred BaderScholarship-Canadian Society forChemistry (2000).

Service to the Chemistry Commu-nity (USA and Canada): Member ofthe ACS since 2006; Alternate Councilor(Jan. 2012-present), Vice Chair of theNSYCC (2010-2011). Member on theNESACS committee for the 2010 ACSmeeting in Boston, MA (Katherine Lee-Chair); President of the 1st Banff Sympo-sium on Organic Chemistry OrganizingCommittee; Member of the CanadianInstitute of Chemistry since 2000.

Position Statement: I am honored tobe nominated for election as a NESACScouncilor. For the past 15 years I havebeen actively involved with serving thescientific community in the UnitedStates and Canada. During my under-graduate studies at Simon Fraser Uni-versity, I was the President of theBiochemistry and Chemistry Under-graduate Student Union. As president Iinitiated a career symposium programwhere students could learn more aboutpotential career opportunities in bothacademic and industrial fields.

During my graduate school trainingat the University of Alberta I establisheda new conference for graduate studentsin Chemistry. The Banff Symposium onOrganic Chemistry is held every twoyears in Banff, Alberta and aims to

highlight graduate student’s researchwhile providing an opportunity to dis-cuss their work with industrial, post-doctoral, and faculty researchers.

For the past few years I have beeninvolved with NESACS. In the winterof 2010 I was a member of theNESACS committee for the 2010 ACSmeeting in Boston. On this committee Iwas responsible for recruiting studentvolunteers working during the nationalmeeting. More recently, I was elected asvice chair of the Younger ChemistsCommittee within NESACS (NSYCC)for year of 2011. With-in this role I wasinvolved in planning of events hosted bythe NSYCC and acted as a moderatorand scientific judge for the annual grad-uate research conference (2011). Lastyear I was fortunate enough to beelected as an alternate councilor for theNESACS (2012-2014) and I am runningagain to be elected as a councilor on theNESACS board.

I am looking forward to build uponmy experiences with NESACS and totake on a more active role within thelocal section here in the Northeast. Ifelected as a councilor, I will continue tomy work with the younger chemists.Younger chemists can learn from theexperiences of our members and bringfresh and new ideas to the section. It isimperative for the future of NESACSand the ACS that we actively engage theyounger chemists of our society. I askfor your vote and thank you in advancefor your support.

Marietta SchwartzEducation: 1983-1988: University of

Wisconsin - Madison. Ph.D. Degree inOrganic Chemistry was conferred inAugust, 1988. 1979-1983: College ofSt. Benedict, St. Joseph, Minnesota.B.A. in Chemistry was conferred inMay, 1983.

Professional Experience: Septem-ber 2011-Present: Associate Dean, Col-lege of Science and Mathematics,UMass Boston; January 2004-Septem-ber 2007: University Director of Under-graduate Studies, University ofMassachusetts Boston; 1994-Present:Associate Professor of Chemistry,UMass Boston; 1988-1994: AssistantProfessor of Chemistry, UMass Boston;1983-1988: Research Assistant/Teach-



ing Assistant, University of WisconsinMadison; 1982-1983: Undergraduateresearch, Department of Chemistry, Col-lege of St. Benedict, St. Joseph, Min-nesota

ACS Service: Member of ACSsince 1980 (Student Affiliate, thenMember). Hospitality Volunteer, 1989National ACS Meeting, Boston.

NESACS Service: Volunteered forthe Education Committee for a numberof years. Sole coordinator in charge ofrecruiting and assigning student workersfor the ACS National Meeting inBoston, August 1998 and again inAugust 2002. Secretary, Board of Publi-cations, October 1999 - December2000; calendar year 2002. Chair, Boardof Publications, calendar year 2001 and2003. Chair of the Norris Award Com-mittee, 2006. NESACS Chair-Elect/Pro-gram Chair, 2007. NESACS Chair,2008. Chair, Nominating Committee,2009. Currently serving as Chair of theEducation Committee and AlternateCouncilor.

Memberships/Honors: AmericanChemical Society (Organic Division,Division of Chemical Education, North-eastern Section), Iota Sigma Pi nationalhonor society (Member-At-Large),Association for Women in Science

Position Statement: The role of thecouncilors is an important one to thesection, as they represent the section tothe larger society and communicatenational decisions back to the local sec-tion. Policy and communication are twoareas that I deal with on a daily basis inmy administrative position and continueto use in my departmental work, and Iwould be honored to have the opportu-nity to utilize those skills to serveNESACS.

Heidi TengEducation: PhD Organic Chemistry,

Northeastern University, 2011; BSChemistry, University of Connecticut,2005; BS Biophysics, University ofConnecticut, 2005

Professional Experience: Scientist,Sigma-Aldrich Fine Chemicals Hitech(2011-present); Chemistry Intern,Boehringer Ingelheim PharmaceuticalsInc (2001-2005)

Service in ACS: Chair, NortheasternSection Younger Chemist Committee,

2011-presentCo-chair, NESACS-YCC/GDCh-JCF

exchange program, 2011-present; Secre-tary, Northeastern Section YoungerChemist Committee, 2010-2011

Position Statement: It is an honor tobe nominated for the position of coun-cilor for NESACS. I have been anactive member of the American Chemi-cal Society throughout my Chemistrycareer. Currently in my second term asthe Chair of the Younger Chemist Com-mittee I have been working diligently topromote careers in chemistry and aidyoung chemist in their professionalgoals. In this role I have enjoyed andbeen successful in organizing events,communicating effectively and promot-ing concepts. I would bring these skillsto the position of councillor. In addition,as Co-chair of the NESACS-YCC/GDCh-JCF exchange I have hadthe opportunity to represent the ACS,learning to work well in a multiculturalgroup. My personal interests are inbridging the gap between young andexperienced chemists (domestically andinternationally), chemical education andeveryday chemistry fun.

Your vote would allow me to continueserving the section in new roles and tohelp drive our chemistry community.

Sonja Strah-PleynetEducation: Ph.D. Organic Chemistry

(1996); M.S. Organic Chemistry (1993);B.S. Chemistry (1990), University ofLjubljana, Slovenia; Postdoctoral Fel-low, University of Florida (1997-1998);Postdoctoral Fellow, University of Cali-fornia, San Diego, School of Medicine(1998-1999).

Professional Experience: Consultant(2011-Present); National Science Foun-dation, Reviewer (2012); Thermedical,Inc. (2012); Arena Pharmaceuticals(1999-2009); Senior Scientist, Medici-nal Chemistry (2006-2009); Scientist II(2005-2006); Research Scientist (1999-2005).

Awards and Honors: ChemLumi-nary Award - ACS President’s Award forLocal Section Government Affairs(2010); American Chemical SocietyCertificate of Achievement, ACS SanDiego Section (2008); Arena Pharma-ceuticals – Outstanding MedicinalChemistry Team Award (2007); Post-

doctoral Fellowship from Ministry ofScience and Technology, Slovenia(1997); First Prize Winner at 26thKRKA Pharmaceuticals ResearchAwards (1996); Graduate ResearchScholarship of Ministry of Science andTechnology, Slovenia (1991-1996).

Service in ACS National Offices:ACS Council (2004-2012); PresidentialTask Force “Vision 2025”, Member(2012-Present); ACS National AwardSelection Committee, Member (2011-Present); Committee on Chemistry andPublic Affairs, Associate (2013), Com-mittee on Economic and ProfessionalAffairs (CEPA), Associate (2005-2006),Member (2007-2012), Subcommittee onPublic Policy; CEPA Liaison to Com-mittee on Minority Affairs (2008-2012);CEPA Liaison to Committee on Interna-tional Activities (2011-2012); ACSIndustry Member Programs –Small/Medium Business AdvisoryPanel, Member (2009-Present); ACSLegislative Action Network, Member(2006-Present); ACS LS LegislativeSummit on Capitol Hill (2006); CEPATask Force on Globalization (2008-2009).

Service in ACS: Member since 1998;ACS Divisions: Organic and MedicinalChemistry, Member (1998-Present);Business Development and Manage-ment (2012-Present); Northeastern Sec-tion: Government Affairs Committee,Member (2010-Present), STEM TaskForce Coordinator (2012-Present);NESACS Website - STEM News Sec-tion Editor (2012-Present); STEM Out-reach - Science Café and Science Fairs(2011-Present); San Diego Section:Executive Board Member (2000-2012),Councilor (2004-2012), Alternate Coun-cilor (2000-2003); Government AffairsCommittee, Chair (2007-2010); ACSCalifornia Government and LegislativeAffairs Committee (2008-2010); West-ern Regional Meeting: Invited speakerat the Women Chemist Symposium(2006); Host Section Volunteer (2007).

Related Activities: Co-inventor on13 US patent applications and numerousinternational patents; Co-author of over30 publications and presentations; Advi-sory Board member, Industrial Allianceto Southwestern College Pharmaceuticaland Laboratory Science (2008-2010);Association for Women in Science,Member (1999-2006); BIOCOM,

Southern California Life Science TradeOrganization, Education CommitteeMember (2008-2010); San Diego Sci-ence Festival Volunteer (2009); Proc-tored local screening exams for theInternational Chemistry Olympiad; Co-authored a wining ACS Local SectionInnovative Project Grant proposal(2009); Advisory Board member,Sneakers to Beakers STEM afterschoolprogram (2012-Present).

Statement: I am honored to be nomi-nated to the position of Councilor forthe Northeastern Section of the Ameri-can Chemical Society (NESACS). Ibring 15 years of ACS volunteer andleadership experience on local andnational level, combined with 10 yearsof professional experience in biophar-maceutical industry. I held positionswith increased responsibilities at ArenaPharmaceuticals in San Diego, prior tomoving to Boston in 2010. I contributedto several multidisciplinary researchprograms in discovery and developmentof novel therapeutics for CNS, cardio-vascular, inflammatory and metabolicdiseases, including two clinical candi-dates. I served on the Executive Boardof the ACS San Diego Section fortwelve years. As a Councilor, I repre-sented the section on the National Coun-cil for nine years. Under my leadership,San Diego Section received nationalACS recognition and won ChemLumi-nary Award - ACS President’s Award forLocal Section Government Affairs, pre-sented at the 2010 ACS National Meet-ing in Boston. As the Chair of theGovernment Affairs Committee for fouryears, I organized and led federal leg-islative district office and Capitol Hillvisits to engage legislators and advocateon issues important to ACS members,such as science research funding, STEMeducation, innovation, green chemistryand sustainability. In this role, I initiatedand developed strategic partnerships andcollaborations between industry, acade-mia and government, ACS and otherscientific organizations. I participated innumerous ACS local section activitiesand committees: Education, NationalChemistry Week, Younger Chemists,Women Chemists, Nominations andWestern Regional Meeting. At thenational level, I served on the Commit-tee on Economic and ProfessionalAffairs and was its liaison to the Com-

mittee on Minority Affairs and Interna-tional Relations.

I have been involved in NESACSactivities for the past two years. Iattended several Board meetings andparticipated in STEM outreach pro-grams. I am currently a member of theGovernment Affairs Committee thatrecently sponsored NESACS SmallChemical Business Symposium. I alsoserve as a STEM task force coordinatorand STEM News editor for theNESACS website. This new websitefeature was created to help publicize,coordinate and encourage variousSTEM activities while providingresources and opportunities forincreased member involvement. I havebeen a passionate advocate for STEMeducation and often shared my experi-ence with students, teachers andyounger chemists, through classroomvisits, science fairs or career develop-ment symposia. I currently serve on thePresidential Task Force ‘Vision 2025’which was appointed by the ACS 2012President-Elect, Dr. Marinda Li Wu, toaddress challenges that globalization ofchemistry enterprise has posed for ACSmembers. The task force provided sev-eral recommendations for ACS leaders,volunteers and staff, to help ACS mem-bers find jobs and thrive in the globalchemistry enterprise.

I welcome this opportunity to take ona new role as NESACS Councilor andbuild on my previous experience. I willcontinue to foster communication andcollaboration between industry, acade-mia and government, our local sectionand national ACS, in order to bringsolutions to complex issues confrontingour members, ACS and chemistry enter-prise. I appreciate your vote for a Coun-cilor and thank you for your support!

Wilton VirgoEducation: Ph.D. in Chemistry, Ari-

zona State University (2005). A.B. inChemistry, Princeton University (2000).

Professional Experience: WalshAssistant Professor of Chemistry,Wellesley College (2008-Present).Research Affiliate, Department ofChemistry, MIT (Present). Visiting Sci-entist, Department of Chemistry, MIT(2008-2009). Postdoctoral Fellow andMLK Scholar, MIT (2006-2008). Post-

doctoral Associate, MIT (2006). Educa-tional Consultant (2000-Present). Pro-fessional Associate, BrookhavenNational Laboratory (2000-2001).Deloitte & Touche consulting summerinternship (1999). Leadership AllianceEarly Identification Program chemistryinternship (1998). Freelance ProposalWriter (1997).

ACS Service: Research presentationat 239th ACS National Meeting, Boston,MA (2010). Research presentation at234th ACS National Meeting, San Fran-cisco, CA (2007).

NESACS Service: NESACS Alter-nate Councilor (2013-2015). Invitedseminar speaker for the NESACSMonthly Meeting at Simmons College(2009). Panelist at the Overcoming Bar-riers Conference sponsored by NSYCC(2009).

Relevant Memberships: AmericanChemical Society (ACS) member(2008-Present). Council on Undergradu-ate Research (CUR) member (2009).President of MIT NOBCChE Chapter(2008).

Honors: Eastman Kodak Dr.Theophilus Sorrell Fellowship Award(2005). Minority Graduate Education @Mountain States Alliance Scholar(2002-2005). Outstanding GraduateResearch Assistant Award at ASU(2003). Rao Prize at OSU 2002 Interna-tional Symposium on Molecular Spec-troscopy (2002). Princeton UniversityChemistry Outreach Program Certificate(2000). Princeton University ChemistryTutor (1997-2000).

Position Statement: My goal as acandidate for the NESACS Councilorposition is to leverage the NortheasternSection’s strength as the largest ACSSection to enhance both the Boston areaand global scientific network, and pro-vide an environment for collaborationacross academia and industry.

As a Councilor, I will diligentlyattend the NESACS Board meetings inorder to uphold the vision of the ACS toimprove lives through the transformingpower of chemistry and the mission toadvance the broader chemistry enter-prise and its practitioners for the benefitof Earth and its people. I will be avail-able to the community at the ACSNational Meetings so that I can repre-sent the interests of the NESACS mem-bers when I serve on NESACS



committees.From 2009-2011, I organized the

Department of Chemistry SeminarSeries at Wellesley College. In 2010, Ico-organized the Junior FacultyResearch Seminars across all Depart-ments at Wellesley College. My role atWellesley included selecting and invit-ing speakers, organizing the seminarschedule, delegating responsibility forhosting and organizing lunches and din-ners with seminar speakers, and publi-cizing the seminars. I will bring mypassion for chemistry and enthusiasmfor committee teamwork to the Coun-cilor position.

TrusteeCharles E. Kolb

Academic Record: MassachusettsInstitute of Technology, S.B., Chem-istry, 1967; Princeton University, M.S.,1968, Ph.D., Physical Chemistry, 1971.

Honors: National Academy of Engi-neering, 2013; ACS Fellow, 2009; ACSNortheastern Section Henry A. HillMemorial Award, 2005; ACS CreativeAdvances in Environmental Science andTechnology Award, 1997; AmericanAssociation for the Advancement ofScience Fellow 2001; American Geo-physical Union Fellow, 2000; AmericanPhysical Society Fellow, 1997; OpticalSociety of America Fellow, 1988;National Associate, National Acade-mies, 2003; Conceptual Foundations ofChemistry Lecturer, Arizona State Uni-versity, 1998; Harris Lecturer, TexasA&M University, 2001; Hottel Lecturer,Massachusetts Institute of Technology,2003; McElvain Lecturer, U. Wiscon-sin-Madison, 2011.Professional Position: AerodyneResearch, Inc., President and CEO,1984 to date.

Service in ACS National Offices:Committee on Environmental Improve-ment, Associate, 2001-02, Member2003-12, Vice-Chair, 2005, Chair, 2006-2008; Presidential Task Force onEnhancing Innovation and Competitive-ness, 2007-08; Editorial AdvisoryBoard, Environmental Science & Tech-nology, 2011 to date. Sundry ACSNational Award and Journal EditorSelection Committees.

Service in NES/ACS Offices: North-

eastern Section: Chair-elect, 1990;Chair, 1991; Trustee, 1994-96; RichardsMedal Committee, Member 1998-06,Chair 2005-06; Esselen Award Commit-tee, Member 2007-11, Chair, 2009-10.

Memberships: American Associa-tion for the Advancement of Science;American Physical Society; OpticalSociety of America; American Geo-physical Union; Combustion Institute;Union of Concerned Scientists. Mem-ber ACS since 1969, ACS Divisions:Environmental Chemistry and PhysicalChemistry.

Position Statement: The NortheasternSection is fortunate to have a significantendowment and its members electTrustees with financial and managerialexperience to protect, enhance and dis-tribute income from those funds. As thechief executive officer of my companyfor the past 28 years, a member of sev-eral foundation and academic manage-ment and advisory boards, and a formerNES/ACS Chair and Trustee, I believe Ihave the experience to perform theduties of NES/ACS Trustee well. Ipledge to do so if elected.

Dorothy PhillipsEducation: Vanderbilt University,

B.A., 1967; University of Cincinnati,Ph.D., 1974

Experience: Retired (March 31,2013); Waters Corporation, 1984 to2013; Life Sciences, Strategic Market-ing

Honors-2010 and 2011: The Ameri-can Chemical Society Fellow, Class of2010; International Year of ChemistryEvents: Invited Speaker at North Car-olina A&T State University Departmentof Chemistry Fourth Bi-annual Chemi-cal Sciences Symposium; InternationalConference on Chemistry for Mankind,Nagpur, India; 15th Indian Society ofChemists & Biologists InternationalConference, Rajkot (Gujarat), India.Honored as the 2011 DistinguishedChemist by The New England Instituteof Chemists (NEIC), Division of theAmerican Institute of Chemists; Invitedspeaker at PepCon in Beijing, China in2010.

Service in ACS National Offices(<10 years): Council Policy Committee,2008-2013; Division of AnalyticalChemistry, Chair, 2009-10,

Program Chair, 2008-09, Chair-elect,2007-08; Committee on Committees,2001-06; Committee on DivisionalActivities, 2007-08.

Service in NESACS Offices: Coun-cilor, 1995-2015; Chair, 1993; Chair-Elect and Program Chair, 1992;AwardsCommittee, Chair, 2009-13; FundraisingCommittee, Chair, 2004-08;ProjectSEED Committee, Chair, 1994- 95;Nominating Committee, Chair, 1994;Centennial Celebration, Co-chair, 1998

Memberships: American Associa-tion of Pharmaceutical Scientists,National Organization for the Profes-sional Advancement of Black Chemistsand Chemical Engineers (NOBCChE).

Position Statement: During my 38years industrial career I gained skillsand expertise in financial management.Being a director at Waters Corporationfor almost 15 years gave ample opportu-nities for working with financial ana-lysts and controllers to manage thebudgets, review profit and loses (P&L)statements, and track trends in sales(CAGR). In addition, I made decisionsbased on these statements and graphs.Combining the expertise gained inindustry with my knowledge ofNESACS I feel qualified to be a Trusteeof the Section. If elected, I promise towork actively with the Board, the otherTrustees and the Treasurer to manageNESACS funds in line with the Sec-tion’s goals.

Director-at-LargeGary Weisman

Education: Primary and secondaryeducation in public schools, Mason,Ohio; B.S. in Chemistry With Distinc-tion, University of Kentucky, 1971;Ph.D. Organic Chemistry, University ofWisconsin-Madison, 1976.

Professional Experience: Post-doc-toral, University of California, LosAngeles, 1976-77; Faculty member ofthe Department of Chemistry, Univer-sity of New Hampshire since 1977, Pro-fessor of Chemistry since 1994; VisitingAssociate Professor, University of Wis-consin, 1986; Visiting Fellow, Univer-sity of Bristol, England, 1987 and 1998;Visiting Professor, Australian NationalUniversity, 2005; Visiting Professor,University of Melbourne, Australia,

2005.Research Interests and Areas of

Expertise: Physical organic chemistry;Synthetic organic chemistry; Synthesis,reactions, special properties and coordi-nation chemistry of amines andpolyamines and derivatives; Liganddesign and synthesis; Biomedical appli-cations of coordination complexes;Supramolecular chemistry; Conforma-tional analysis; Use of NMR in struc-tural and conformational analysis oforganic and metallo-organic com-pounds.

ACS Service: Co-Program Chair ofNERM 2001, the 30th NortheastRegional Meeting of the AmericanChemical Society, Durham, NH; Sym-posium Organizer, “Symposium inHonor of Robert E. Lyle”, 30th North-east Regional Meeting of the AmericanChemical Society (NERM 2001), Uni-versity of New Hampshire, Durham,NH, June 24-27, 2001; Organizer andPresider, James Flack Norris Award inPhysical Organic Chemistry; Sympo-sium to Honor Hans J. Reich, 243rdNational Meeting of the AmericanChemical Society, San Diego, CA,March 25, 2012.

NESACS Service: Director–at-Large, 2002-2009 (2 terms); Member,Richards Medal Award Committee,2004-2005; Chair, Richards MedalAward Committee, 2006-2007; Alter-nate Councilor, 2010-2012.

Relevant Memberships, Etc.: ACSMember since 1970; Sigma Xi - TheScientific Research Society of NorthAmerica; International Society of Hete-rocyclic Chemistry; Reviews Editor,Journal of Physical Organic Chemistry,2006-present.

Honors:1976-present; Excellence inTeaching Award, College of Engineer-ing and Physical Sciences, UNH, 1995;Wilsmore Fellow, University of Mel-bourne, Australia, 2002; Elected Vice-Chair (2003) and Chair (2005), GordonResearch Conference on PhysicalOrganic Chemistry; Gloria G. andRobert E. Lyle Professorship, Depart-ment of Chemistry, UNH, 2005-2009;Excellence in Teaching Award, Collegeof Engineering and Physical Sciences,UNH, 2009.

Position Statement: I wouldbe pleased to serve as Director-at-Largeof the NESACS if the members choose

that I do so. I would do my best to rep-resent the views of the members of themore northern reaches of NESACS andto participate in an informed manner inthe Section’s business.

John L. NeumeyerEducation: BS Columbia University,

1952; PhD in Medicinal Chemistry,University of Wisconsin in 1961.

Professional Experience ResearchChemist, Ethicon (Division of J& J)1952-1957; FMC Corp., SeniorResearch Chemist 1961-1963; Arthur D.Little Inc, Staff Scientist 1963-69; Pro-fessor of Medicinal Chemistry andChemistry, Northeastern University1969-1991; Visiting Professor Univer-sity of Konstanz, Germany 1975-76;Sci-entific Director and Chairman, ResearchBiochemicals Int’l (RBI) 1980-96; Vis-iting Professor University of Groningen,Holland 1997; Director, MedicinalChemistry Program, McLean Hospital,Harvard Medical School 1996-present.

Honors: ACS Fellow, 2011; Electedto Hall of Fame, ACS Division of Med.Chem., 2008; Henry Hill Award forOutstanding Service to NESACS, 1998;AAAS Fellow, 1984; Fulbright Fellow-ship, 1975-76; AAPS Fellow, 1986,Outstanding Educator Award, 2012;Northeastern University Matthews Dis-tinguished Professor, 1980.

ACS Service: Division of MedicinalChemistry, Councilor, ExecutiveComm., 1971-1981; Vice Chairman,1981; Chairman, 1982; Councilor,1983-1987; Board of Editors, J. Med.Chem., 1974-1995; ACS Board of Pub-lications, 1990-93.

NESACS Service: Founder andChair, Medicinal Chemistry Group,1974-1975; Councilor, 1988-1995;Trustee 1989-1993; Alt. Councilor,1995-98; Publication Comm. TheNucleus, 1976-78, 1985-87 and Chair,1986 and 1997.

Position Statement: Having servedthe ACS in a variety of positions bothnationally and locally over the past 45years, I am very much aware of the con-cerns and problems of its members. Ifelected, I shall continue to devote mytime, energy and experience in bothindustry and academia to further theobjectives of the ACS and its members.In particular, I shall work towards

recruiting young and energetic newmembers to actively participate in thegovernance of the Northeastern Section.

David J. HarrisEducation: B.S., Chemistry, Boston

College, 1976; Ph.D. Organic Chem-istry, Brandeis University, 1982

Professional Experience: Post-doc-toral Research Associate, MassachusettsInstitute of Technology, (1982-1984);Principle Scientist Chemical ProcessResearch (highest position), Schering-Plough Corporation, (1984-1990);Group Leader (1990-1992), Senior Sci-entist (1992-1994), Associate DirectorChemistry (1994-1997), Senior DirectorChemistry (2001-2004), Vice Presidentof Chemical Process Development(2004-2008), Group Vice PresidentPharmaceutical Development Sciences(2008-2011) Genzyme Corporation;Group Vice President and Acting Headof Drug & Biomaterial R&D (2011-2012), Head of Pre-Development Sci-ences LGCR Boston & Waltham SiteHead (2012 –present) Genzyme aSanofi Company

NESACS Service: Director at Large2011 to present; Member GermanExchange Organizing Committee 2012to present

Memberships: American ChemicalSociety (Organic and Medicinal Chem-istry Divisions), American Associationfor the Advancement of Science, Ameri-can Association of Pharmaceutical Sci-ences

Position Statement: It is both anhonor and a privilege to be nominatedfor the position of Director-at-Large forthe Northeast Section. My chemistryexperiences are diverse. I am a co-inventor of three technologically distinctclinical candidates. They are an enzymeinhibitor for Gaucher disease (Eliglustatin Phase III trials), a polymeric phos-phate binder for renal disease, and acationic lipid gene transfer agent forcystic fibrosis. In my current role atSanofi/Genzyme I lead the SynthesisDevelopment, Formulation Develop-ment, and Analytical R&D organiza-tions, as well as lead the Waltham Site.Major functions of NESACS includerepresenting the interests of its membersand providing opportunities for mem-bers to interact, network, and dissemi-



nate information. Through the BostonCollege and Brandeis University alumninetwork, I often share my broad experi-ences in the biopharmaceutical industrywith young scientists as they examinepotential careers. I believe my extensiveexperiences in chemistry, my interest inassisting young chemists, and my lead-ership position at a major pharmaceuti-cal company will provide me with anexcellent background to be an effectiveDirector-at-Large. With the help of yourvote I will strive to increase industrialparticipation at NESACS events (forexample by hosting events at ourWaltham site as done in 2012) and tosupport the health and growth of theNESACS.

Mukund S. ChorghadeEducation: B.Sc. 1971; M. Sc. 1973

(1st Class Honors) University of Poona,India; Ph.D. (Organic Chemistry), 1982,Georgetown University

Professional Experience: ResearchFellow, National Chemical Laboratory(1973-74); Instructor, Georgetown Uni-versity (1981-82); PostdoctoralResearch Assoc., University of Virginia(1982-84); Postdoctoral Research Fel-low, Harvard University (1984-85);Senior Research Chemist (1985-89);Project Leader (1989-90), Dow Chemi-cal Co.; Research Scientist/AssistantDirector, College de France, Paris andUniversite Louis Pasteur (1990-91);Project Manager, Abbott Laboratories,Pharmaceutical Research (1991-95);Senior Director, Chemical SciencesResearch & Development, CytoMed,Inc. (1997-98); President, CP Consult-ing, Chorghade Enterprises (1995 topresent); Visiting Scholar, University ofBritish Columbia, University ofChicago, Northwestern University, Cal-tech, Cambridge University; Vice Presi-dent, Pharmaceutical DevelopmentSciences, Geltex Pharmaceuticals / Gen-zyme , (2000 to 2003); President andChief Scientific Officer, PharmaceuticalSciences Division, D & O Pharmachem(2003-present), CSO & CTO, THINQPharma (2006-), Founder and CTO ,Ascent Therapeutics (2006-), Director,MS Program in Drug Discovery andDevelopment, Mass. College Of Phar-macy (2006-), Adjunct Research Profes-sor, Northeastern University (2009-),

CSO, E#MPIRIKO (2011-present)ACS Service: Member since 1982.

Chair, Brazosport Section (1990);Organic Division, member; Chairman,Symposium on Industrial Chem., GreatLakes Meeting, May, 1997; VisitingSpeakers Program (1999 to present);Department of Career Services Consult-ant (2000 to present); Member, Interna-tional Activities Committee(2003-present), Chair and ImmediatePast Chair, SCHB (2010-), Chair,Awards Subcommittee, ComSci (2010-)

NESACS Service: Board of Direc-tors (1997-present), Public ServicesCommittee, Chair; Professional Serv-ices Committee, member and chair(2005-); Public Affairs Committee; Pub-lic Relations Committee, Interim Editor,The Nucleus (2004), NESACS Chair-elect (2006), Chair (2007-2008), Direc-tor (2008-)

Memberships, Honors: MaharashtraAcademy of Sciences (Elected Fellow);Andhra Pradesh Academy of Sciences(Elected Fellow) IUPAC; Royal Societyof Chemistry (Elected Fellow); NewYork Academy of Sciences; AmericanInstitute of Chemists (Elected Fellow);AAAS; Sigma Xi; Indian Society ofBio-Organic Chemists; IUPAC Com-mission on Biotechnology, MedicinalChemistry, New Technologies and Spe-cial Topics, Titular member, Division ofChemistry and Human Health; 20th

IUPAC Conference on the Chemistry ofNatural Products, Chicago, 1996; Chair,Scientific Programs Comm., on Advi-sory Board for Organic ProcessResearch and Development, ChimicaOggi; Member, Committees onAdvanced Professional Thinking, Inter-national Activities and Technology,American Institute of Chemists.Awarded “Diamond Jubilee Fellow-ship”, Univ. Dept. of Chemical Technol-ogy, Mumbai, India- Awarded “B.D.Tilak Distinguished Visiting Fellow-ship”, University of Bombay, India.Awarded “Bharat Gourav” Award, Gov-ernment of India. “Alkyl Amines PadmaBhushan Prof. B.D. Tilak Chemcon2002 Distinguished Speaker Award”.Listed in American Men and Women ofScience, Who’s Who in Science andEngineering Invited speaker at numer-ous international conferences

Position Statement: It is a singularhonor and privilege to have been nomi-

nated to the position of Director for theNortheastern Section.

It will be my endeavor to effectivelyrepresent the Northeastern Sectioneffectively at the Local and Nationallevel. The issues confronting the Chem-ical Enterprise in the USA and the ACSare complex and demand creative solu-tions. I will spare no effort in ensuringthat the voice of our electorate is heardand that the council determines effectivepolicies for all our members. My exten-sive experience in NESACS, mostrecently as Chair, Director and NationalACS governance has given me the nec-essary background to effectively repre-sent the section.

Nominating CommitteeSophia R. Su

(For all information on this candi-date see Councilor/Alternate Coun-cilor statement on Page 13)`

Heidi Teng(For information on education, honor,

and experience see Councilor/AlternateCouncilor statement on page 16)

Position Statement: It is a greathonor and privilege to be asked to runfor a position on the Nominating com-mittee. I have always been active in theACS, but in the last 2 years I haveincreased my involvement as Chair ofthe Younger Chemist Committee. Ihave seen first hand how important it isto recognize and promote chemists inour community. As a member of thenominating committee I will be able todo so. I believe my experience in acade-mia, pharma and Hitech industries givesme the breadth of knowledge to servethe section well in this role.

I would appreciate your vote for thenominating committee so I may con-tinue to serve NESACS in excitingroles.

Marietta Schwartz(For all information on this candidate

see Councilor/Alternate Councilor state-ment on Page 15)

Raj Rajur(For information on education, hon-

ors, and experience see Councilor/Alter-nate Councilor statement on page 14)

Position Statement: The nominatingcommittee is a critical function of thelocal section. I strongly believe it is amajor way to involve new people ingovernance of NESACS and its awardsand programs. I have had the privilegeof inviting and interacting with severaltopnotch scientists from many academicinstitutes and pharmaceutical andbiotech companies during my tenure asProgram Chair for the Medicinal Chem-istry Division and would consider it anhonor to serve on this committee. I havebeen a member of NESACS and Pro-gram Chair of the Medicinal ChemistryDivision for the past several years. Ifelected to the Nominating Committee Iwill help to broaden the selection ofcandidates for future elections. Thankyou for considering my candidacy.

Esselen Award CommitteeJeffrey Steinfeld

Professor Emeritus of Chemistry,Massachusetts Institute of Technology,Cambridge, Mass. 02139. B.S. inChemistry (M.I.T. 1962), Ph.D. in phys-ical chemistry (Harvard University,1965). N.S.F. Postdoctoral Fellow withthe late Lord George Porter at the Uni-versity of Sheffield (U.K. 1965-66).M.I.T. Chemistry Departmentsince1966.

Research on molecular spectroscopy,molecular energy transfer, and laserapplications to chemistry, includingoptical methods for remote sensing andatmospheric monitoring. Author of text-books on molecular spectroscopy [Mol-ecules and Radiation, 2nd ed., M.I.T.Press, 1985; Chinese translation, 1983;Dover Publications Reprint Edition,2004] and chemical kinetics [ChemicalKinetics and Dynamics, with J.S. Fran-cisco and W.L. Hase, Prentice-Hall,1989; 2nd ed., 1999; Japanese transla-tion, 1995]. Co-editor of SpectrochimicaActa, Part A, 1983-1998.

Visiting appointments at the Univer-sity of California, Berkeley and Univer-sity of Leiden, Netherlands [J.S.

Guggenheim Memorial Fellowship,1972 - 73], University of Southern Cali-fornia [1981], Joint Institute of Labora-tory Astrophysics, Boulder, Colo.[1983], Université de Bourgogne, Dijon,France [1991], University of Sydney,Australia [1999], University of TokyoGraduate School of Frontier Sciences[2008]. Co-chair, Symposium on FutureTrends in Spectroscopy (Vatican City,1989). Member, American PhysicalSociety [Fellow, Division of ChemicalPhysics], American Chemical Society[Fellow], American Association for theAdvancement of Science [Fellow], PhiLambda Upsilon, Sigma Xi, Federationof American Scientists, and Union ofConcerned Scientists.

The present focus is on introducingconcepts of sustainability and environ-mental stewardship across the curricu-lum. Member [1997 – 2004] and Chair[1999 – 2002], American ChemicalSociety’s Committee on EnvironmentalImprovement. Richard Awards Commit-tee member, NESACS, 2008 – 2012.Received 1999 ACS Director’s Awardfor Advancing ACS Public Policy inEnvironment, for work to encourage theuse of sound science in global climatechange policy, and 2004 “PropheticVoice for Sustainability Award” fromMassachusetts Interfaith Power & Light.

Eric Jacobsen(No Statement Submitted)

Vinod PatelEducation: B.Sc. (First Class Hon-

ours) Leicester Polytechnic, UK (1984);Ph.D. Industrial Trainee, Kodak Ltd.,UK (1983), Nottingham University, UK(1987), Industrial Trainee, May &Baker, UK (1986)

Professional Experience: Post-Doc-toral Fellow, University of Rochester,USA (1988-1989); Eli Lilly & Co(1990-1999); Kinetix Pharmaceuticals(1999); Amgen (1999-2011); Sanofi(2011 to Present)

NEACS and ACS Service: ACSmember since 1989; Co-chair, ACSProSpectives (2009); Speaker, NEACS(Mediicnal Chemistry (2007), Speaker,ACS ProSpectives (2006)

Position Statement: I have been anACS member since 1989. During the

past 23 years of my career, I have beenfortunate to collaborate with fellow sci-entists in industry as well as in acade-mia. I believe my experience throughthese interactions would be beneficial tofurther the aspirations of our localNEACS. Toward this end, I would bedelighted to serve as a committee mem-ber for the Esselen Award.

Karl HansenEducation: B. Sc. University of

Delaware (1993), A.M. Harvard Univer-sity (1995), Ph.D. Harvard University(1998)

Honors: Phi Beta Kappa, ACS Divi-sion of Organic Chemistry Pre-GraduateFellow 1996, Eli Lily Predoctoral Fel-low (1996), Presidential Green Chem-istry Award Contributor (Emend®,2005), ICheme AstraZeneca® GreenChemistry and Chemical EngineeringAward Contributor (Emend®, 2005),Merck Chairman’s Award for Sustain-ability Contributor (2006), PresidentialGreen Chemistry Award Contributor(Januvia®, 2006)

Professional Experience: MerckProcess Research and Development, Sr.Research Chemist, Research Fellow,Associate Director (1998-2006); AmgenSmall Molecule Process and ProductDevelopment, Scientific Director(2006-present)

Service: University of Delaware ACSstudent affiliate president (1992), ACSmember (1993-Present), Chairman ofthe 60th Gordon Research Conference onNatural Products (2011)

Position Statement: I would be hon-ored to serve on the Esselen AwardNominating Committee. I have beenable to enjoy the benefits of ACS mem-bership for nearly twenty years andwould be thrilled to have an opportunityto serve on this committee.

Richards Award CommitteeJerry Jasinski

Education and Honors: B.A.,M.S.T., University of New Hampshire(1964, 1968); M.N.S., Worcester Poly-technic Institute (1968); Ph.D.; NATOSummer Research Fellow, University ofCopenhagen, Chim Lab-IV (1972);Associated Western Universities (AWU)



Pre-Doctoral Fellow at the Los AlamosScientific Laboratory (1973); Universityof Wyoming (1974); Post Doctoral Fel-low at the University of Virginia (1975);Vermont Sigma Heroes Award (1995);1st Recipient of the Keene State CollegeAward for Faculty Distinction inResearch and Scholarship (2001); Mar-quis Who’s Who in America, the World,Science & Engineering (2010-2013);Presidential Who’s Who (ChemistryProfessor of the Year) and Hall of Fame(2011, 2012); Cambridge Who’s Who(Professional of the Year in ScientificResearch & Education) (2010-11);Towle High School Athletic Hall ofFame (2011).

Professional Experience: KeeneState College: Assistant Professor(1978-83), Associate Professor (1983-89), Professor (1989-), Chair, Depart-ment of Chemistry, (1999-2005).University of Virginia: Post DoctoralResearch Associate (1974-75). LosAlamos Scientific Laboratory: AWUPre-Doctoral Research Associate (1973-74), High School Chemistry/PhysicsTeacher (1964-70, 1975-78). AmericanInstitute of Chemists (AIC-Board ofDirectors 1999-01, 2007-2009, Presi-dent 2009-2011, Chair of the Board2011-): (New England Institute ofChemists, NEIC, Treasurer, 1988-).Coeditor of Acta Crystallographica,Section E (2009-). Editorial Board forthe Journal of Crystallography (2012-).Coauthor of over 400 refereed papers inpeer-reviewed chemical research jour-nals.

Research and Interests: Physical-Bioinorganic Chemistry; Synthesis andX-ray crystallography of pharmaceuti-cally active molecules, laser dye mole-cules and transition metalthiosemicarbazones. Co-developer of aweb-based tutorial for crystallographyentitled “Symmetry and Space Groups”.Introduction of Process OrientedGuided Inquiry Learning (POGIL) tech-niques into the chemistry curriculum.

ACS Service: Member since 1970.Member of INOR division. NESACS:Nominating Committee (2000-01, 2007-08); Alternate Councilor (2007-09;2010-12; 2013-2015); Chair of the Nor-ris Committee (2009-2012, 2012).

Memberships: American ChemicalSociety (ACS), New England Section ofthe American Chemical Society(NESACS), American CrystallographyAssociation (ACA), New England Insti-tute of Chemists (NEIC), Council forUndergraduate Research (CUR), NewEngland Association of ChemistryTeachers (NEACT).

Position Statement: I consider it anhonor and privilege to continue to serveand represent all of you in theNESACS. Serving on these variouscommittees over the past several yearshas allowed me to give back in a mostconstructive manner. I value the oppor-tunities for service given to me in thisregard. I have served on the NorrisAward Committee and greatly enjoyedthis opportunity. As an active scientistand chemical educator with an expand-ing portfolio in the crystallographiccommunity, I would very much like tohave the opportunity to serve on theRichards Medal Committee. This willonly be possible with your support andtherefore, I ask for your vote. Thanks!

Howard R. Mayne Professor, Department of Chemistry,

University of New Hampshire, Durham,NH 03824

Education: B.Sc. (’74), M.Sc.(’75), Ph. D. (’77), University of Man-chester, UK

Employment: Postdoctoral, Max-Planck-Institut für Strömungsfors-chung, Göttingen, Germany (’77-’79);Research Associate, University ofToronto (’79-’83); Assistant Professor.Eastern Michigan University (‘83-‘85);Assistant Prof; UNH (’85 -’90); Assoc.Prof. (‘90-’94); Professor (‘94-date);Chair (‘98-‘04).

Visiting Positions: UC Santa Bar-bara; Northwestern U.

Research: Physical Chemistry,Chemical Physics. Atmospheric Chem-istry. Gas phase reaction dynamics; gas-surface interactions; nanotechnology;Over eighty papers in peer-reviewedjournals.

Honors: UNH Outstanding FacultyAward (1990); Outstanding TeacherAward, UNH College of Engineeringand Physical Sciences (1990); Ronald T.Pflaum Outstanding Chapter AdvisorAward, Alpha Chi Sigma (2008).

Memberships: ACS, AmericanPhysical Society, Alpha Chi Sigma

Previous ACS Service: Co-chair,Local Committee, ACS National His-toric Chemical Landmark, UNH (1999);General Chair, Northeast RegionalMeeting (NERM 2001); Chair, NERMSteering Committee (2001-2003);NESACS National Meeting Committee(2002), NESACS Alternate Councilor(2002-2006); Norris Award Committee(2003-2006, Chair 2005), EsselenAward Committee (2009-2013, Chair2012)

Morton Z. HoffmanEducation: Hunter College, A.B.,

1955; University of Michigan, M.S.,1957; University of Michigan, Ph.D.,1960.

Professional Experience: Sheffield(England) University: PostdoctoralResearch Associate, 1960-61; BostonUniversity: Assistant Professor, 1961-67; Associate Professor, 1967-71; Pro-fessor, 1971-2005; Professor Emeritus,2005-present.

ACS Service: SOCED Task Force onUndergraduate Programming atNational Meetings, 1991-2002; CollegeChemistry Consultants Service, 1995-2009; Editorial Advisory Board, ACSGeneral Chemistry Textbook Project,1999-2004; SOCED, 2002-11; Interna-tional Activities Committee, 2012; Sen-ior Chemist Task Force, 2008-12;Member, Senior Chemists Committee,2013-14. Division of Chemical Educa-tion: Program Committee, 1992-2004;International Activities Committee,1993-present; Regional Meetings Com-mittee, 2000-2009; Chair-Elect, Chair,Immediate Past Chair, 2004-06.

NESACS Service: Board of Direc-tors, 1993-present; Education Commit-tee, 1993-present; German ExchangeSteering Committee, 2001-present;Councilor, 1994-present; Chair-Elect,Chair, Immediate Past Chair, 2001-03;Feature Editor, Photographer for TheNUCLEUS, 2005-present; Norris AwardCommittee 2007-2010; NERM Com-mittee, 2007-present; IYC Committee,2011-12.

Relevant Memberships: AAAS;NEACT; IUPAC. ACS Divisions: Inor-ganic Chemistry; Physical Chemistry;

NESACS Electioncontinued from page 21


Chemical Education.Honors: Fellow, AAAS, 1992; Met-

calf Cup and Prize, Boston University,1994; Hill Award, NESACS, 1999; Cat-alyst Award, American ChemistryCouncil, 2002; Timm Award, NEACT,2003; U.S. National Representative tothe Committee on Chemistry Educationof IUPAC, 2004-present; Norris Award,NESACS, 2005; Professional Achieve-ment Award, Hunter College AlumniAssociation, 2006; ACS Award for Vol-unteer Service, 2007; Visiting ScientistAward, Western Connecticut Section,ACS, 2007; ACS Fellow, 2009.

Research Area and Interests: Physi-cal-Inorganic Chemistry: Photochem-istry and photophysics of transitionmetal coordination compounds; photo-chemical conversion and storage ofsolar energy; use of radiation in thestudy of free radical reactions and thechemistry of unusual oxidation states;fast kinetics techniques. Chemical Edu-cation: New pedagogical strategies ingeneral chemistry; use of technology toenhance classroom communication.

James P. MorkenBorn in Concord, CA in 1967, he

obtained his B.S. in chemistry in 1989from UC Santa Barbara working withProf. Bruce Rickborn, and a Ph.D. fromBoston College in 1995 with Prof. AmirHoveyda. He was an NSF PostdoctoralFellow with Stuart Schreiber at HarvardUniversity and, in 1997, joined the Uni-versity of North Carolina at Chapel Hillas an Assistant Professor.

James was promoted to AssociateProfessor in 2002 and in 2006 joined thefaculty of Boston College as a Professorof Chemistry. His research focuses onthe development of transition-metal-cat-alyzed asymmetric processes and theiruse in complex molecule synthesis. Hehas been a member of the AmericanChemical Society since 1988. u


JerryJasinskiReceivesFulbrightGrantJerry P. Jasinski, Professor of Chem-istry at Keene State College in Keene,NH, has been awarded a FulbrightScholar grant to lecture and doresearch at The University of Mysore,Mysore, India, during the 2013-2014academic year.

Through this exchange, Dr. Jasin-ski will advance the knowledge base ofstudents and faculty at the Universityof Mysore and affiliated institutions inthe use of single-crystal X-ray crystal-lography as a modern state-of-the-arttool in the determination of molecularstructure.

Recently, in collaboration with hismany regional, national and interna-tional scientific colleagues, he achieveda milestone by co-authoring over 400research papers in major refereed scien-tific journals related to his work, whichmore recently has focused on the X-raycrystallography of biologically andpharmaceutically significant mole-cules.

His recent award of $290,000from the National Science Foundationfor the purchase of a new state-of-the-art CCD single-crystal X-ray diffrac-tometer system has allowed him toextend his research activities to includeKSC undergraduate students as well asfaculty and students from several NewEngland Colleges (Dartmouth, Middle-bury, Williams, St. Anselm’s, ClarkUniversity, UMASS-Boston, FairfieldUniversity, and the University of NewHampshire). As a coeditor of ActaCrystallographica-Section E (a majoronline international research journal),his international reputation has resultedin significant collaborations with fac-ulty and students at the University ofMysore, the University of Mangalore,

JIWAJI University, Guru Nanak DevUniversity, Manipur University, andthe University of Bombay in India, aswell as with faculty and students at theUniversity of the West Indies-CaveHill, Earciyes University, Turkey, Uni-versity of Mashhad, Iran, Faculaté desSciences et Techniques University,Senegal, Allama Iqbal Open Univer-sity, Pakistan, and the Nelson MandelaMetropolitan University, Port Eliza-beth South Africa.

He states, “Working in a team-ori-ented format and bringing togetherideas and frontier research problemsinvolving crystallography with under-graduate, graduate, and post-graduatestudents, as well as faculty fromaround the globe, is not only stimulat-ing to me, but also to our KSC under-graduates who have gained and willcontinue to gain unprecedented expo-sure and interaction in such an envi-ronment, often leading to selectiveentrance of these undergraduates toquality graduate schools or positions inscience related industry or as scienceteachers in a most competitive world.We continue to push back the frontiersof science in the solid state andembrace an interaction of cooperation,collaboration and mutual respect withall levels of individuals and genderwho have the desire and work ethic tosucceed by giving them the chance toexperience a hands-on approach to 21st

century in science.” Over the past 4years, Prof. Jasinski has co-authoredover 40 papers a year, a phenomenalpace at any institution, and particularlyat Keene State College.

Dr. Jasinski is one of approxi-mately 1,100 U.S. faculty and profes-sionals who will travel abroad throughthe Fulbright U.S. Scholar Program in2013-2014.

The Fulbright Program is the flag-ship international educational exchangeprogram sponsored by the U.S. govern-ment, and is designed to increasemutual understanding between the peo-ple of the United States and the peopleof other countries. The primary sourceof funding for the Fulbright Program isan annual appropriation made by theU.S. Congress to the U.S. Department


NESACS Electioncontinued from page 22

The synthetic enzyme substrateswere designed and made to include astructure moiety recognized by theenzyme. Most of the LSD substratesinclude carbohydrate moieties (glucose,galactose, N-acetyl galactosamine, a-L-iduronic acid, etc.) with a or b gly-cosidic linkages. Several LSDenzymes are sulfatases that recognizeO- or N-sulfate groups in particularpositions of the sugar molecules. Forexample, mucopolysaccharidosis IIItypes A and D (also known as Sanfil-ippo syndromes) are caused by defi-ciency of enzymes degrading theglycosaminoglycan heparan sulfate byselectively stripping sulfate groupsfrom glucosamine-N-sulfate and N-acetylglucosamine-6-O-sulfate unitsthat are linked by a-glycosidic bonds toglucuronic acid. The synthetic sub-strates must encompass these structurefeatures to be recognized by theenzymes. Another example concernsthe two most common forms of CDGcaused by deficient enzymes phospho-mannoisomerase (PMI) and phospho-mannomutase isozyme 2(PMM2). PMIworks on converting fructose-6-phos-phate to its isomer mannose-6-phos-phate to be converted by PMM2 toanother isomer, mannose-1-phosphate,which is then used to build glycanantennas in glycoproteins. Distinguish-ing these isomeric molecules by massspectrometry was quite challengingand required a special strategy of cou-pled enzyme assays to succeed.

Quantitative analysis of enzymeactivities by mass spectrometry relieson the simultaneous determination ofenzyme products and internal stan-dards. The latter are synthetic com-pounds that are chemically very similarto or identical with the enzyme prod-ucts but are distinguished by molecularmass owing to the presence of stableheavy isotopes or homologous groups.The chemical similarity of productsand internal standards ensures that theresponse of the mass spectrometer tothese compounds is also very similarwhich simplifies analysis.

Enzyme assays are carried out in

biological samples that are very com-plex mixtures of many compoundtypes (DNA, proteins, lipids, saccha-rides) and include exogenous compo-nents such as buffer salts, detergents,inhibitors, and other additives. Thismandates that after incubation the assaysample be purified to exclude compo-nents that would interfere with ioniza-tion and mass spectrometric analysis.In our initial approach, we used affinitypurification based on the highly spe-cific and reversible non-covalentbiotin-streptavidin interaction (2). Sub-strates and internal standards were syn-thesized that contained a covalentlylinked biotin moiety that served as anaffinity handle for affinity purification.This approach, in combination with sta-ble isotope labeling, was extended bycollaborators to protein analysis usingin vitro derivatization, proteolysis, andbottom-up peptide quantification. Thismethod, called Isotope-Coded AffinityTags (ICAT for short), was introducedin 1999 and pioneered quantitative pro-tein analysis in the then burgeoningfield of proteomics (3).

Affinity purification with strepta-vidin immobilized on polymer beads,followed by mass spectrometry analy-sis, was suitable for applications inclinical diagnostics and was semi-auto-mated using a lab-on-valve apparatusfor bead injection that was coupled tothe mass spectrometer.

Enzyme assay developmentinvolved a thorough analysis ofenzyme kinetics and optimization ofexperimental conditions. Lysosomalenzymes work in an acidic environ-ment of pH 4.0-4.5 and so the pHdependence of their in vitro activity forthe synthetic substrates had to beestablished. The substrate conversionwas purposefully limited to a few per-cent to maintain pseudo first orderkinetics and linear time dependence ofproduct formation. Linear dependenceon the substrate and enzyme concen-tration was also tested. Interferingenzymes present in the biological sam-ple were suppressed by specificinhibitors.

In 2001, the late Nestor Chamolesreported that lysosomal enzymes retainlatent activity in dried blood spots and

can be assayed after rehydration in asuitable buffer (4). This discoverycaused a major change in the directionof our research of LSD that ever sincehas focused on dried blood spots(DBS)(5). Since DBS are used as acommon biological sample in newbornscreening, our efforts were focused onretooling our chemistry of substratesand internal standards, bioanalyticalwork up procedures, and mass spectro-metric analysis. Particular emphasishas been placed on multiplexing allthese steps so that multiple enzymeactivities could be determined simulta-neously in one or two parallel DBSincubations. Our new generation sub-strates were designed to comprise threemajor parts: (i) a structure moiety thatis recognized by the enzyme, (ii) agroup allowing facile introduction ofstable isotope label, and (iii) a func-tional group directing the ion fragmen-tation in the mass spectrometer intoone dominant channel producing thereporter ion. At the same time, thecompounds were designed such thatthe enzyme reaction products werereadily separated from the incubationmedium by a single step procedure,e.g., extraction or ultrafast chromatog-

Esselen Awardcontinued from page 2



of State, Bureau of Educational andCultural Affairs. Participating govern-ments and host institutions, corpora-tions and foundations in foreigncountries and in the United States alsoprovide direct and indirect support.Recipients of Fulbright grants areselected on the basis of academic orprofessional achievement, as well asdemonstrated leadership potential intheir fields. The Program operates inover 155 countries worldwide. u

Jerry Jasinskicontinued from page 23

This was a very successful sciencecafé since we met some new NESACSmembers and many members of thepublic audience (75% of the attendees)have a new appreciation for science. u

Science Cafecontinued from page 4


raphy. As of now, we have developedsubstrates and procedures for 15 lyso-somal enzymes, galactocerebroside b-galactosidase (GALC), acidsphingomyelinase (ASM), acid b-glu-cocerebrosidase (ABG), acid a-galac-tosidase (GLA), acid a-glucosidase(GAA), a-L-iduronidase (IDUA),iduronate-2-sulfatase (IdS), N-acetyl-galactosamine-4-sulfatase (aryl sulfa-tase B, ASB), N-acetylgalactosamine-6-sulfate sulfatase (GALNS), heparanN-sulfatase (sulfamidase), α-N-acetyl-glucosaminidase, acetyl-CoA:α-glu-cosaminide acetyltransferase, N-

acetylglucosamine-6-sulfatase, palmi-toyl protein thioesterase (PPT), andtripeptidyl peptidase 1 (TPP1). Thefirst six of these enzymes have beenincluded in a six-plex procedure that isbeing tested in a pilot program of new-born screening in Illinois. A pilot studyof a triplex assay (GLA, GAA andIDUA) has been successfully carriedout with >100,000 samples in Wash-ington state (6). A diagnostic newbornscreening of GALC deficiency(Krabbe disease) has been running inNew York state that has so far includedover 1,000,000 samples. Further tech-nological advances pursued in our lab-oratory include ultra-fast highperformance liquid chromatography

for sample purification after incubation(7) and design of new substrates. References(1) The Metabolic and Molecular Bases of

Inherited Disease; Scriver, C.,Beaudet, A., Sly, W., Eds.; McGrawHill: New York, 2001.

(2) Gerber, S. A. et al. J. Am. Chem. Soc.1999, 121, 1102-1104.

(3) Gygi, S. P. et al. Nature Biotechnol.1999, 17, 994-999.

(4) Chamoles, N. A. et al. Clin. Chim. Acta2001, 308, 195-196.

(5) Li, Y. et al. Clin. Chem. 2004, 50,1785-1796.

(6) Scott, C. R. et al. J. Pediatrics 2013,162, in press.

(7) Spacil Z. et al. Clin. Chem. 2013, 59,in press. u

Esselen Awardcontinued from page 24

education. Tom teaches general chem-istry and science education courses andconducts professional developmentworkshops for K–12 teachers. He haswon Northeastern’s Excellence inTeaching Award and the OutstandingTeacher of First-Year Engineering Stu-dents Award (twice). He is a Fellow ofthe American Chemical Society and in2012 was elected to the A.C.S. Boardof Directors. In 2010 he received theHenry A. Hill Memorial Award fromthe A.C.S. Northeastern Section. u

Gilbert Biographycontinued from page 5

students, followed by an activity inwhich they explore the “greater truth”within the story through guided inquirycan be an effective teaching tool.

This presentation will be largely ademonstration of how contextualizedguided inquiry can engage chemistrystudents. We will start with a sunnysummer day in 1983 and a bunch ofkids racing go-karts on the runway ofan abandoned air base in western Man-itoba. All of a sudden they look up andsee an Air Canada 767 about to land onthe same runway. The pilot had nochoice: his plane was out of fuel. Howcould that happen? I’d tell you, butwhy ruin a good story? u

Gilbert Abstractcontinued from page 5

course might encourage students whowould never voluntarily take a coursein chemistry to enroll in this course asa science elective.

During our presentation, we willdiscuss the list of activities that wehave developed, including, but not lim-ited to:

1. What is light?2. Why are objects colored?3. What is the difference between

organic and inorganicchemicals,and what are they used for?

4. What are pigments? What is thehistory of pigment use?

5. What are dyes?6. How are paints made?7. What is the difference between

additive and subtractive colormixing?

8. How is redox chemistry used byartists?

9. How is acid base chemistry usedby artists?

10. What are glass and ceramicsmade of?

11. How does classical photographywork?

There will be an opportunity to workthrough one or two activities as amember of a learning team, to modelits use in a classroom. u

Chemistry Workshopcontinued from page 6

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B U S I N E S S D I R E C T O R Y

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CAREER SERVICESSERVICES

B U S I N E S S D I R E C T O R Y

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Index of AdvertisersAsisChem, Inc. ....................26ChemDev Solutions ..............4Eastern Scientific Co.............2Front Run OrganX, Inc........26Huffman Laboratories, Inc. .14Mass-Vac, Inc. .....................13MIT Professional Education.28Micron Inc. ..........................26New Era Enterprises, Inc.....26NuMega Resonance Labs....26Organix, Inc.........................26PCI Synthesis ......................27PolyOrg, Inc. .......................27Rilas Technologies, Inc. ......10Robertson Microlit Labs. ....26VACCUBRAND .................11Waters Corporation .............27

Check the NESACS home pagefor late Calendar additions:http://www.NESACS.orgNote also the Chemistry Department webpages for travel directions and updates.These include:http://www.bc.edu/schools/cas/chemistry/semina

rs.htmlhttp://www.bu.edu/chemistry/seminars/http://www.brandeis.edu/departments/chemistry/

events/index.htmlhttp://www.chem.harvard.edu/courses/seminars.

phphttp://chemcalendar.mit.edu/index.phphttp://chem.tufts.edu/seminars.htmlhttp://engineering.tufts.edu/chbe/newsEvents/se

minarSeries/index.asphttp://www.chem.umb.eduhttp://www.umassd.edu/cas/chemistry/http://www.uml.edu/Sciences/chemistry/Semina

rs-and-Colloquia.aspxhttp://www.unh.edu/chemistry/events

May 01Prof. Timothy Warren (Georgetown University)Harvard, Pfizer Lecture Hall 4:15pm to 5:15pm

May 02Buchi Lectures in Organic Chemistry Prof. Carolyn Bertozzi (U.C.-Berkeley)MIT, 6-1204:00 pm

May 03Buchi Lectures in Organic Chemistry Prof. Carolyn Bertozzi (U.C.-Berkeley)MIT, 6-1204:00 pm

May 06Novartis SymposiumProf. Elizabeth Jarvo (U. C.-Irvine) TBA (Novartis Research Scientist )Harvard, Pfizer Lecture Hall 4:15pm

May 08Prof. Pingyun Feng (U.C.-Riverside)MIT, 6-1204:15 pm

May 09Boehringer-Ingelheim Lecture in OrganicChemistry: Prof. Dean Toste (U.C.-Berkeley)Dr. Jeff Song (Bristol-Myers Squibb)MIT, 6-1204:00 pm

May 14Prof. Daniel Lidar (Univ. Southern California)MIT, 6-1204:30 pm

May 20Boehringer-Ingelheim Symposium Prof. Sarah Reisman (Cal. Tech.)Dr. Christopher Senanayake (Boehringer-Ingelheim, Inc)Harvard, Pfizer Lecture Hall4:15 pm

Notices for The NucleusCalendar of Seminars should be sent to:Sheila E Rodman, email:serodman(at)hotmail.com

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Join NESACSon facebook

www.facebook.com/nesacs

NESACSArchivesMoveThe NESACS Archives were movedfrom their location of many years inthe basement of the Regis CollegeLibrary to a new temporary location atSigma-Aldrich Corporation in Natick,MA. A more permanent long-termstorage location is desired.

NESACS expresses great appreci-ation to Regis College for allowingNESACS to store its archives in itslibrary. NESACS is further apprecia-tive of Michael Singer and Sigma-Aldrich for making storage spaceavailable while a more permanentsolution is sought. u

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