Novel Bioactive Inorganic Materials Challa V. Kumar, University of Connecticut, DMR 0300631
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Transcript of Novel Bioactive Inorganic Materials Challa V. Kumar, University of Connecticut, DMR 0300631
Novel Bioactive Inorganic MaterialsChalla V. Kumar, University of Connecticut, DMR 0300631
• Novel, benign, and general method was developed to intercalate enzymes in inorganic layered -Zr(HPO4)2H2O (A-D)
• These materials show strong promise for the economic production of biofuels.
• Novel, DNA-based hybrid nanobiocatalysts were synthesized for the first time (E).
• DNA made significant improvements in enzyme structure and activity. This is a significant progress for biocatalytic function.
• These materials show high promise for improving the function of biosensors.
R
Zr(IV)
PO3
R
R = OH
O
OH
HO O
OH
OH
O
HO
OHO
ZrP -ZrCMP -ZrCEP
C
B
A
Exfoliation
Intercalated Enzyme
-Zr(HPO4)2H2O
D E
Enzyme/DNA/ZrP
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Novel Bioactive Inorganic MaterialsChalla V. Kumar, University of Connecticut, DMR 0300631
• Education - Several graduate and undergraduate students were trained
• Undergraduate Research - numerous Chemistry Interns and summer REU students were trained in Inorganic Materials Research
• High School outreach- Under the Mentor Connection Program at UCONN, each summer two to four high school students spent three weeks in our laboratory synthesizing novel Inorganic Materials
• Organized Odyssey 2006 Chemistry Fair for Middle School students
• Participated each year in ‘Kids are Scientists Too’ summer program for elementary school children.
Mentor Connection ParticipantFrom Putnam High School 2005.
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