Norquay Technology Inc. Moving forward, in Fine & Specialty Chemicals P.O. Box 468 Chester, PA 19016...

Norquay Technology Inc.

Moving forward, in

Fine & Specialty ChemicalsP.O. Box 468Chester, PA 19016 USA

phone: +1(610) 874-4330fax: +1(610) 874-3575

www.NorquayTech.com

www.NorquayTech.com 2

today’s discussion

Overview Custom Synthesis Seven (7) Day Guarantee Equipment Product Lines

Contact Information


Roach’s Shipyard, old Chester Harbor, 1859-1885

Chester Waterfront ca 1875

1927-1961


The

Chester plant

www.NorquayTech.com5

Norquay TechnologyChester plant

1927-1961

6

Norquay Overview

Founded 1987: Philadelphia, PA Focus

Niche MarketsHigh Value-added $15.00 - $42,000/kgKilo-Lab: 10 grams to 20 kgLow Volume 50 kg to 85+tpyCommercial Scale 100-1,500 gal

Products Sales Custom Synthesis: 50% Product Line: 50% Export: 30%:

Europe, South America, Japan & Asia

www.NorquayTech.comto Contents to Products

7

Seamless Scale-up

Laboratory, Kilo-lab,

Pilot PlantCommercial Quantities

Compound pricing studies, Economic Model

Confidentiality Agreements


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Equipment

Kilo Lab: ( 5-12-22-30-50 liter)

Plant Reactors: jacketed, condensers & instrumentation Hastelloy –C-276:20-100-350 gal 316 Stainless Steel: 500-1,500 gal Glass Lined: 100-500-750-1,000 gal

Vacuum Distillation: 50 liter to 100-500-1,500 gal <1.0 torr 10 – 25 theoretical plates

Filter-Drying: air & moisture sensitive

Drying: shelf, double-cone & rotary (316 s/s)

Utilities: -78° to 170o C (future to 220o C)

Analytical: HPLC, GC, NMR, UV, L-a-b color, Karl Fischer, etc.

www.NorquayTech.comto Contents to Products to Products

Formal Response “Yes” or “No” within Seven (7) Days

9

NORQUAY: Seven (7) Day Guarantee


Project Defined, unequivocally

Chemical Name, CAS Number

Scope Volume, Timing, Stage GATE Process

How is Success measured? (Step 3)

Outline Open IssuesTSCA LVE or REACh for Europe

Customer Clarifying Questions Key Parameters, measure of SUCCESS Analytical Methods- Need development?Alignment between customer “ Use Test” & QC Methods

TimingQuote to first lab sample <?>Qualification (3 lots?)Steps to commercial scale?

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NORQUAY: Seven (7) Day Guarantee



NQ: Product Lines

؏ Substituted Benzophenones ؏ Phenylhydrazines & Indoles ؏ Cyanoacetates ؏ Heterocycles ؏ Metallocenes, cp-ligands ؏ HPLC/Process Surfactants: Sulfonates ؏ Chlorendate Esters

To Contents

12

Benzophenonesbenzophenone CAS #

1 . 2,4- Dihydroxy benzophenone 131-56-62 . 2,2',4,4'- Tetrahydroxy benzophenone 131-55-53 . 2- Hydroxy -4-allyloxy benzophenone 2549-87-34 . 2- Hydroxy -4-methoxy benzophenone 131-57-75 . 2- Hydroxy -4-methoxy benzophenone -5-sulfonic Acid 4065-45-66 . 2,2'- Dihydroxy -4,4'-dimethoxy benzophenone 131-54-47 . 2,2'- Dihydroxy -4-methoxy benzophenone 131-53-38 . 2,2'- Dihydroxy -4,4'-dimethoxy benzophenone -5,5'-disulfonic Acid Na Salt 76656-36-5

2,2'4,4'- Tetrahydroxy benzophenone2,2'- Dihydroxy -4,4'-dimethoxy benzophenone

bis (2,4- Dihydroxy phenyl) methanonebis (2- Hydroxy-4-methoxyphenyl) methanone

13 . 2- Hydroxy -4-octyloxy benzophenone 1843-05-614 . 4,4'- Difluoro benzophenone 345-92-615 . 4,4'- Dimethoxy benzophenone 90-96-016 . 4,4'- Dimethyl benzophenone 611-97-217 . 2,4- Dimethyl benzophenone 1140-14-318 . 4- Fluoro benzophenone 345-83-519 . 4- Morpholino benzophenone 24758-49-4

sulfonic acid

9

9

.

.

substituents

1341-54-4

1341-54-4


13

Benzophenones

O

OOH

OH

OOH

OH

OH

OH

OOH

O

CH2

OOH

O

OH

OCH3 CH3

OOH

OCH3

OOH

O

OH

CH3

OOH

OCH3

SO3H

O OH

OC8H17

O

F F

O

CH3 CH3

O

O OCH3 CH3

OCH3

CH3

O

F

O

N

O

OOH

O

OH

OCH3 CH3

SO3-Na

+SO3

-Na

+


O OH

OCH3

SO3H

O OH

OCH3

O OH

OH

PRODUCT OVERVIEW

Primary Use Solubility UV Spectrum (g Product / 100ml Solvent) (30°C)

Helisorb-1 (Benzophenone-1) 2,4-Dihydroxybenzophenone • Cosmetics Water: Insoluble Bath Preparations Methanol: 32.0 Shampoos Ethanol: 32.0 Blushes Nail Polish / Enamel • Paints • Plastics WAVELENGTH λ max: 292/330nm

Helisorb-3 (Benzophenone-3) 2-Hydroxy-4-methoxybenzophenone

• Cosmetics Bath Preparations Water: Insoluble Colognes / Perfumes Methanol: 6.0 Sunscreens Ethanol: 6.0 • Paints • Plastics WAVELENGTH λ max: 285/320nm

Helisorb-4 (Benzophenone-4) 2-Hydroxy-4-methoxybenzophenone- 5-sulfonic acid • Cosmetics Water: 28.0 Bath Preparations Methanol: 40.0 Fragrances, Cologne Ethanol: 35.0 Hair Care Blushes Skin Care • Paints • Plastics WAVELENGTH λ max: 285/320nm

UV-C UV-B UV-A

80%

20%

UV-C UV-B UV-A

40%

20%

UV-C UV-B UV-A

20%

% T

RA

NS

MIT

TA

NC

E

100%

40%

0% 240 260 280 300 320 340 360 380 400

% T

RA

NS

MIT

TA

NC

E

100%

80%

60%

0% 240 260 280 300 320 340 360 380 400

% T

RA

NS

MIT

TA

NC

E

100%

80%

60%

40%

240 260 280 300 320 340 360 380 400

10mg/l 20mg/l 40mg/l

60%

0%

Helisorb-11 (2,2’-Dihydroxy-4,4’-dimethoxybenzophenone)

(Benzophenone-6)

• Cosmetics Water: Insoluble Nail Polish Methanol: <1.0 Nail Enamels Ethanol: <1.0• Plastics• Films

Helisorb-11DS (2,2’-Dihydroxy-4,4’-dimethoxybenzophenone-

(Benzophenone-9) 5,5’-disulfonic acid sodium salt)

Bath Preparations Water: 5.0 Hair Cosmetics Methanol: 2.0 Shampoos Ethanol: 1.0 Skin Products

Helisorb-10 (2,2’,4,4’-Tetrahydroxybenzophenone)

(Benzophenone-2)

• Cosmetics Water: .10 Toilet Water Methanol: 50.0 Fragrances Ethanol: 40.0 Perfumes Shampoos Skin Products• Plastics / Paints

OOH

OH

OH

OH

OOH

O

OH

OCH3 CH3

OOH

O

OH

OCH3 CH3

SO3-Na

+SO3

-Na

+

To Contents


Phenylhydrazines

CH3

NHNH2

ClH

F

NHNH2

ClH

NHNH2

F

ClH

NH

NH2

Br

ClH

Cl

NHNH2

ClH

NHNH2

Cl

ClH

NHNH2

Cl

Cl

ClH

NHNH2

CH3

ClH

NHNH2

CH3

ClHNH

NH2

CH3

ClH

Br

NHNH2

ClH

O

NH

NH2

CH3

ClH

CH3

NH NH2

CH3

ClH

N

NH2ClH

To Contents

Phenyl hydrazine CAS #

1 . 2- Bromo phenyl hydrazine HCl 50709-33-6

2 . 4- Bromo phenyl hydrazine HCl 41931-18-4

3 . 2- Chloro phenyl hydrazine HCl 41052-75-9

4 . 4- Chloro phenyl hydrazine HCl 1073-70-7

5 . 2,4- Di chloro phenyl hydrazine HCl 5446-18-4

6 . 3,5- Di chloro phenyl hydrazine HCl 63352-99-8

7 . 3,4- Di methyl phenyl hydrazine HCl 60481-51-8

8 . 1,1- Di phenyl hydrazine HCl 530-47-2

9 . 2- Ethyl phenyl hydrazine HCl 19398-06-2

10 . 2- Fluoro phenyl hydrazine HCl 2924-15-4

11 . 4- Fluoro phenyl hydrazine HCl 823-85-8

12 . 4- Methoxy phenyl hydrazine HCl 19501-58-7

13 . 2- Tolyl hydrazine HCl 635-26-7



Substitution

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Specialty Cyanoacetates

for: Specialty Adhesives Medical devices Disposable Components

NCO-R

O

NCO

O

CH3

NCO

O

CH3

NCO

O

CH3

NCO

O

CH3

NCO

O

CH3

CH3

NCO

O

CH3

CH3

NCO

O

CH3

CH3

NCO

OCH3

CH3

NCO

O

OCH3

NCO

O

CH3

CH3

O-CH3

NCO

OO CH3


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Specialty Cyanoacetates

cyanoacetate CAS1 . n- Propyl cyanoacetate 14447-15-52 . n- Hexyl cyanoacetate 13361-53-03 . n- Octyl cyanoacetate 15666-97-44 . n- Decyl cyanoacetate 17686-43-05 . Isopropyl cyanoacetate 13361-30-36 . Isobutyl cyanoacetate 13361-31-47 . Isoamyl cyanoacetate 60180-49-68 . 2- Octyl cyanoacetate 52688-08-19 . "2- Methoxyethyl" cyanoacetate 10258-54-5

10 . "2- Methoxyisopropyl" cyanoacetate 32804-79-811 . "2- Ethoxyethyl" cyanoacetate 32804-77-6

substituent


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Heterocycles



Heterocycles

N

N

OH

N

H3C-O O

O

O-CH3H3C-O

N

O

SH

O

H3C-O

H3C-OO

O-CH3

O-CH3

NH

NH

O

N

NH

OH

S

NH

CH3

CH3

S

NH

CH3

F

To Contents

CAS # Chemical Name2 . 5,6-dimethoxy indanone 2107-69-9 5,6-dimethoxyindanone3 . 2,5-Dimethyl benzothiazole 95-26-1 2,5-Dimethylbenzothiazole4 . 5-Fluoro-2-methyl benzothiazole 399-75-7 5-Fluoro-2-methylbenzothiazole1 . 2- Benzoxazole thiol 2382-96-9 2-Benzoxazolethiol5 . 2-Hydroxy benzimidazole 615-16-7 2-Hydroxybenzimidazole6 . 3,6-Dimethoxy xanthone 1214-24-0 3,6-Dimethoxyxanthone7 . 6-Hydroxy quinoline 580-16-15 6-Hydroxyquinoline8 . 6-Methoxy quinoline 5263-87-6 6-Methoxyquinoline9 . Julolidine 479-59-4 Julolidine

Chemical Name

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etallocenes, Ligands

metallocene CAS #1 . 5-Hexene-2-one 109-49-92 . Vinyl cyclohexane 695-12-53 . 1,4-Bis(1-hydroxycyclopentyl) butadiyne 104766-62-34 . t-Butyl cyclopentadiene 41539-65-55 . Diphenyl fulvene 2175-90-86 . 1,2,3,4-Tetramethyl cyclopentadiene 4249-10-97 . 1,2,3,4,5-Pentamethyl cyclopentadiene 4045-44-78 . Ferrocene tech 102-54-59 . Acetyl ferrocene 1271-55-2

10 . Vinyl ferrocene 1271-51-811 . 1,1-Bis(diphenyl phosphino) ferrocene 12150-46-812 . 1,1-Bis(diphenyl phosphino) ferrocene Pd (II) dichloride 72287-26-413 . Pentamethyl cyclopentadiene titanium trimethoxide 123927-75-314 . Pentamethyl cyclopentadiene titanium trichloride 12129-06-515 . 1-dimethyl- 2,3,4,5-Tetramethyl cyclopentadiene silyl t-butylamine 125542-04-316 . 2,3,4,5-Tetramethylcyclopentadienyldimethylsilyl-t-butylamido titanium dichloride 135072-61-6

Ligand


CAS # Chemical Name109-49-9 5-Hexene-2-one695-12-5 Vinylcyclohexane

104766-62-3 1,4-Bis(1-hydroxycyclopentyl) butadiyne41539-65-5 t-Butylcyclopentadiene2175-90-8 Diphenylfulvene 4249-10-9 1,2,3,4-Tetramethylcyclopentadiene4045-44-7 1,2,3,4,5-Pentamethylcyclopentadiene102-54-5 Ferrocene (Technical Grade)

1271-55-2 Acetylferrocene1271-51-8 Vinylferrocene12150-46-8 1,1-Bis(diphenylphosphine) ferrocene72287-26-4 1,1-Bis(diphenylphosphine) ferrocene Palladium chloride

123927-75-3 Pentamethylcyclopentadiene titanium trimethoxide12129-06-5 Pentamethylcyclopentadiene titanium trichloride

125542-04-3 2,3,4,5-Tetramethylcyclopentadiene-1-dimethylsilyl-t-butylamine135072-61-6 2,3,4,5-Tetramethylcyclopentadienyldimethylsilyl-t-butylamido titanium dichloride


etallocenes, Ligands

CH3

CH3

CH3

CH3

CH3

CH3 CH3

Si

CH3

CH3

NHCH3

CH3

CH3

To Contents

22

Alkyl Sulfonates

HPLC: high purity Reagent Grade Industrial surfactants Dial-In properties

From C-2 to C-16Salts; Na, K, Li etc

Alkyl sulfonic acidsSodium <25 – 50 ppm


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Alkyl Sulfonates (& their free acids)

SO3Na • H2Oor

CH3(CH2)7SO3Na • H2O

SO3Na

or

CH3(CH2)15SO3Na

CH3 (CH2)3 SO3Na

SO3Na

or

1-Butane sulfonic acid sodium salt

1-Hexadecane sulfonic acid sodium salt

1-Octane sulfonic acid sodium salt monohydrate


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Tentative Specifciations Appearance slightly yellow transparent liquid

Color (APHA): max 700 Acid value (mg KOH/g): < 0.1Assay: Develop GC method PropertiesSpecific gravity (20°C): 1.380 - 1.400 g/ccEster value (mg KOH/g): 223 (no limit)Refractive Index (25°C): 1.512 (no limit)

Chlorendate- DBC

ClCl

Cl

Cl

Cl

ClO-nBu

O

O

O-nBu


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Chlorendate- DEC, DBC, DEHC

ClCl

Cl

Cl

Cl

Cl

O

O

O

O

CH3

CH3

ClCl

Cl

Cl

Cl

ClO-nBu

O

O

O-nBu

ClCl

Cl

Cl

Cl

Cl

O

O

O

O

CH3

CH3

CH3

CH3


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Contact Us

Business DevelopmentRobert W. Heldt PresidentTel +1(610) 874-4330Fax +1(610) 874-3575 [email protected]

Sales & MarketingJohn C. Wetzel, Ph.D.Director of Sales & MarketingTel +1(610) 874-4330Cell +1(803) [email protected]

For more information contact:

cell +1(610) 945-8676


Norquay Technology Inc. Moving forward, in Fine & Specialty Chemicals P.O. Box 468 Chester, PA 19016...

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Transcript of Norquay Technology Inc. Moving forward, in Fine & Specialty Chemicals P.O. Box 468 Chester, PA 19016...