New Toxicology Database

Tracie Phillips, Ph.D.Toxicology DivisionTexas Commission on Environmental QualityAdvanced Air Permitting Seminar-October 2014

Objectives

• Introduce New Database• Demo of Database Prototype• Testing the Database

THE NEW TOXICOLOGY DATABASE

A new beginning

NEW

What is the new database?

Housed within the TAMIS database

One stop shop:• ESL List• AMCV List• Supporting

documents

Why are we changing?

• Reduce errors• Proper database structure• More information/detail• Dynamic

Manual Spreadsheets

1000’s of Chemicals

Errors & Frustration

What will be different?

1. No more “Published List” spreadsheets

What will be different?

2. Information will be dynamic

Database

Updates

New Info

What will be different?

3. ESL requests

• Consult the database 1st

• No verification for existing values

Database = Real Time

• At least a 2-week turnaround:• Each value documented

• Should be received early in the permitting process

New ESL Request

What will be different?

4. All associated documentation will be linked:

• DSDs• Fact sheets• Public comments• Interim documentation

What will be different?

5. Screening level reports

ReportsToxicology Reports

ESLEffects Screening Levels

SummaryValues used in

Permitting Only

DetailAll Values (Health &

Welfare)

AMCVAir Monitoring

Comparison Values

What will be different?

6. More detail will be available:• Each value will be dated

Substance CASNo. Phase

Short-term ESL-

Health (ug/m3)

Short-term ESL-

Health (ppb)

Date Derived Status

Interim Source

Used for Air

Permitting Review

Short-term ESL-

Odor (ug/m3)

Short-term ESL -

Odor (ppb)

Date Derived Status

Odor Source

Used for Air

Permitting Review

antimony 7440-36-0 PM10 5 -- 10/1/2003 InterimNIOSH,

TLV, OSHA YES -- -- -- -- -- --benzene 71-43-2 -- 170 54 3/1/2011 Final -- YES 8700 2700 10/17/2007 Final -- --

cyclohexene 110-83-8 -- 600 180 6/28/2010 Interim

NIOSH, TLV, OSHA, FRG-MAK -- 10000 3000 6/28/2010 Interim Amoore YES

What will be different?

7. Source codes

Odor Interim

Long-term Short-term

What will be different?

8. List will be searchable by:

• Date• Substance:

• CAS#• Identified synonyms

• Substance type:• Alcohols• Surrogates

What will be different?

9. Use of surrogates:• Promotes consistency

Children

Parent Chemical A

Chemical X

Chemical Z

What will be different?

10. Identified synonyms

Styrene

Phenyl- ethylene

Vinyl benzene

Styrene Monomer

What is the timeline?

(4) Full Production – No More Published List:Date TBD

(3) Transition

& Beta Testing: Date TBD

(2) External

User Testing:Date TBD

(1) Internal

User Testing:Date TBD

PROTOTYPE DEMOTime for a conceptual demonstration

**For example purposes only, the following is not a true representation of the final product

TAMIS Welcome Screen

Login Screen

Report Selection Screen – Wizard Mode

Date Selection Screen

Report Parameter Criteria Screen

File Delimiter Selection Screen

Report Generation Screen

Report Output in Excel

Substance CASNo. Phase

Short-term ESL

(ug/m3)

Short-term ESL

(ppb)Date

Derived StatusChemical

BasisInterim Source Odor Source

Long-term ESL

(ug/m3)

Long-term ESL

(ppb)Date

Derived StatusChemical

BasisInterim Source

DSD derived date DSD Fact Sheet

Public comments Appendices

benzene 71-43-2 170 54 3/1/2011 Final Health 4.5 1.4 2/1/2011 Final Health 2/1/2011 http:/… http:/… http:/… http:/…

benzene polymer 71-43-2 MUST MEET

NAAQS

benzene resin 71-43-2 CONTACT

TOXICOLOGY

ethylene 71-85-1 1400 1200 4/15/2008 Final Odor PEL 34 30 4/15/2008 Final Health 4/15/2008 http:/… http:/… http:/… http:/…hydrogen fluoride

and soluble inorganic

fluorides, for permit reviews in

agricultural areas with cattle,

as HF 7664-39-3 3 3.7 (24 h) 9/15/2003 Final animal 0.75 0.91 9/15/2003 Final animal 9/15/2003 http:/… http:/… http:/… http:/…hydrogen fluoride

and soluble inorganic

fluorides, for permit reviews in

agricultural areas, as HF 7664-39-3 3 3.7 (24 h) 1/23/2013 Final vegetation 0.6 0.75 1/23/2013 Final vegetation 1/23/2013 http:/… http:/… http:/… http:/…

hydrogen fluoride and soluble

inorganic fluorides, as HF 7664-39-3 PM10 18 22 5/23/2007 Final Health 8.7 11 5/23/2007 Final Health 5/23/2007 http:/… http:/… http:/… http:/…

glycols, polyethylene, mono-(1,1,3,3-

tetramethylbutylphenyl) ether 9036-19-5 PM10 50 -- 1/23/2013 Interim Health NESCAUM 5 -- 1/23/2013 Interim Health 1/23/2013 http:/… http:/… http:/… http:/…

glycols, polyethylene, mono-(1,1,3,3-

tetramethylbutylphenyl) ether 9036-19-5 VAPOR 600 -- 5/23/2007 Interim Health Leonardos 60 -- 5/23/2007 Interim Health TLV-TD 5/23/2007

glycols, polypropylene,

2,3-epoxypropyl ether (DER 736 Epxoy Resin) 9072-62-2 PM10 50 -- 1/23/2013 Interim Odor Nader 5 -- 1/23/2013 Interim Health 1/23/2013

glycols, polypropylene,

2,3-epoxypropyl ether (DER 736 Epxoy Resin) 9072-62-2 VAPOR 1000 -- 5/23/2007 Interim Odor Leonardos 100 -- 5/23/2007 Interim Health 5/23/2007

TESTING THE DATABASETesters Wanted!

External Testing

If you would like to participate, send an email to:

• Tracie Phillips: Tracie.Phillips@tceq.texas.gov

-or-• Toxicology Division: tox@tceq.texas.gov

Tracie Phillips, Ph.D.512-239-2269Tracie.Phillips@tceq.texas.gov

To improve is to change; to be perfect is to change often.

-Winston Churchill