Neuropsychiatric aspects of HIV

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NEUROPSYCHIATRIC ASPECTS OF HIV/AIDS Dr V K Sahu Resident Psychiatry

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NEUROPSYCHIATRIC ASPECTS OF HIV/AIDSDr V K Sahu Resident Psychiatry

OverviewIntroduction (In brief about HIV)Epidemiology of HIV (World and India)Neuropathogenesis of HIVNeuropsychiatric aspects of HIVConclusionReferences

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IntroductionOriginated from primates of west AfricaClosely related to SIVS (Simian Immunodeficiency Virus)SIV found in sub species of chimpanzee( Pan troglodytes)HIV & SIV comprise the lentivirus.HIV able to infect various of cell typesCD4+ T Lymphocytemacrophage

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Clinical stage 3Unexplainedi severe weight loss (>10% of presumed or measured body weight)Unexplained chronic diarrhoea for longer than one monthUnexplained persistent fever (above 37.6C intermittent or constant,for longer than one month)Persistent oral candidiasisOral hairy leukoplakiaPulmonary tuberculosis (current)Severe bacterial infections (such as pneumonia, empyema, pyomyositis,bone or joint infection, meningitis or bacteraemia)Acute necrotizing ulcerative stomatitis, gingivitis or periodontitisUnexplained anaemia (


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