Neuroanatomy Cns 2013

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    GROSS

    NEUROANATOMY

    DESWATYFURQONITA

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    TopicsofNeuroanatomy:y Centralnervoussystem:

    y Protectionofthebrain

    y Cerebral(Cerebrum)

    y Brainstem:midbrain,ponsandmedullaoblongata

    y Cerebellar (Cerebellum)

    y Spinalcord

    y Vascularisation

    y

    Ventricle

    system

    and

    CSF

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    TopicsofNeuroanatomy:y Peripheralnervoussystem

    y Cranialnerves

    y Spinalnerves

    y Anatomicalpathways

    y Ascendingtracts

    y Descendingtract

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    Embryonicdevelopmentofthebrain

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    Embryonicdevelopmentof

    the

    brain

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    PROTECTIONOFTHEBRAINy Structureswhichprotectedthebrainare:

    y SCALP:Skin,Connectivetissue,AponeuroticGalea,LooseconnectivetissueandPericranium

    y Skull(cranium)

    y Meninges

    y CerebroSpinalFluid

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    SCALPANDMENINGES

    Figure1.Meninges around thebrain.

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    MENINGESy Themeningesarecomposedofthreemembranous

    connectivetissue

    layers:

    y Duramater:though,thickexternalfibruslayer

    y

    Arachnoid

    mater:

    thin

    intermediate

    layery Piamater:delicateinternalvasculatedlayer

    y Arachnoidmaterandpiamaterarecontinous

    membranesthat

    collectively

    make

    up

    the

    leptomeninx

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    MENINGES

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    DURAMATERy Theduramater(dura),atwolayeredmembranethatisadherenttotheinternalsurfaceofcanium,consistof:

    y Anexternalperiosteallayery Aninternalmeningeallayer

    y

    Reflection

    or

    reduplication

    of

    the

    meningeal

    layer

    ofdura:

    y Falxcerebri

    y Tentoriumcerebelli

    y Falxcerebelli

    y Diaphragmasellae

    y Bloodsuply: middlemeningealarteries.10furqonita_2013

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    DURAMATER

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    DURALSINUSESSuperiorsagittalsinus

    Inferiorsagittalsinus

    Straightsinus

    Transversesinus

    Occipitalsinus

    Confluenceof

    sinuses

    Cavernoussinus

    Intercavernoussinus

    Superiorpetrosalsinus

    Inferiorpetrosal

    sinus

    Basilarplexussinu

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    DURALSINUSES

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    DURALSINUSES

    Figure2.Meninges around thebrain.

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    MENINGEALSPACESy Theduracraniuminterface(Extraduralspace orEpidural

    space)isnotnaturalspacesbetweencraniumandexternalperiosteallayer of theduramaterbecausetheduraisattachedtothebone.itbecomesaspaceonlypathologically.

    y Thedura

    arachnoid

    junction

    or

    interface

    (Subdural

    space)

    islikewise notanaturalspacebetweentheduraandthearachnoid. aspacemaydevelopasaresultoftrauma.

    y Subarachnoidspace:

    the

    space

    between

    arachnoid

    mater

    andpiamater. itsrealaspacethatscontainsCSF,trabecularcells,cerebralarteriesandsuperiorcerebral

    veins.

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    POTENTIALSPACES

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    Headinjuriesandintracranialhemorrhage

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    MENINGEALSPACESy Cisterns:areasofsubaracnoidspacewherethebraincountourisgreatlychangedsuchthatthepiaand

    arachnoiddiverge

    from

    each

    other.

    y Majorsubarachnoidcisternincludethe:

    y

    Posterior

    cerebellomedullary

    cistern

    (Cisterna

    Magna)y Lateralcerebellomedullarycistern

    y Pontocerebellarcistern(cisternapontis)

    y

    Quadrigeminalcistern

    y Chiasmaticcistern

    y Interpeduncularcistern (cisternabasalis)

    y Lumbalcistern

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    CISTERNS

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    CEREBRUM(TELENCEPHALON)y Thecerebrumhastwohemispheres(rigthandleft)

    whichseparated

    by

    longitudinal

    fissure.

    y Therearegyry,sulciandfissuresonthesurfaceofcerebralhemisphere.

    y Eachhemispherehasfivelobes:

    y Frontallobe

    y Parietallobe

    y Occipitallobe

    y Temporallobe

    y Insula

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    CEREBRUM

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    CEREBRUMy Principlefissureorsulcionthelateralviewofthe

    cerebrum:

    y

    Lateralfissure

    (of

    Sylvian)

    y Centralsulcus(ofRoland)

    y Thecerebrumiscomposedofasuperficialcerebralcortex of

    gray

    matter,

    the

    cerebralwhitematter

    internaltoit,andthedeepgraymatterofthecerebrumwithinthewhitematter (Basalganglia).

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    CEREBRUM

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    CEREBRUMy Specialfeaturesonthelateralviewofthecerebrum:

    y Precentralgyrus theprimarymotorcortex

    y Postcentralgyrus therimarysensorycortex

    y

    Superior

    temporal

    gyrus

    the

    primary

    auditory

    cotexy Occipitalpole theprimaryvisualcortex

    y Triangularpartandopercularpartofinferiorfrontal

    gyry Brocasspeech

    area

    y Angular gyrusandsuramarginalgyrusWernickesspeecharea

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    Functionalareasofcerebralcortex

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    CEREBRUM

    y Outstandinglandmarksonthemedialviewofcerebrum:

    y Corpuscallosum

    y Thefornix

    y Theseptumpellucidum

    y Anteriorcommisure

    y Principalfissuresandsulcionthemedialviewofcerebrum:

    y Calcarinefissure

    y Cingulatesulcus

    y

    Parietooccipital

    fissure

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    CEREBRUM

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    Themedialviewofcerebrum

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    y Lobesonthemedialviewofcerebrum:

    y Frontallobe cingulategyrusandparacentrallobule

    y Parietallobe rostrally:frontallobe,posteriorly:parietooccipitalfissure

    y Occipitallobeisdividedintocuneusandlingualgyrusbycalcarinesulcus.

    y Temporallobe

    CEREBRUM

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    Functionalareasofcerebralcortex

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    Bodymapsintheprimarymotorcortexandsomatosensorycortex ofthecerebrum.

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    Cerebralwhitemattery Underlyingthegraymatterofthecerebralcortexisthe

    cerebral whitematter.

    y Itisviathemanyfibersthatformthecerebral whitematterthatthevariousareasofthecerebralcortexcommunicate bothwithoneanotherandwiththebrainstemand spinalcord.

    y

    Most

    of

    these

    fibers

    are

    myelinated

    and

    bundled into

    largetracts.

    y Thefibersareclassifiedascommissuralfibers,associationfibers,orprojectionfibers.

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    Whitefibertractsofcerebralhemispheres

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    Whitefibertractsofcerebralhemispheres

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    Deepgraymatterofcerebrum(BasalGanglia)

    y Deepwithinthecerebralwhitematterlies agroupof

    brainnuclei

    collectively

    called

    the

    basalganglia :

    y Caudatenucleusy Lentiformenucleus:

    y Putameny Globuspalidus

    y Claustrum

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    BASALGANGLIA

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    DIENCEPHALONy Thediencephaloniscomposedoftheepithalamus,

    thalamus,and

    hypothalamus,

    encloses

    the

    3rd

    ventricle.

    y Thethalamusapairedeggshapedgroupofbrainnuclei,isthe gatewaytothecerebralcortex.

    y Thethalamusisamajorrelaystationforsensory

    impulses

    ascending

    to

    the

    sensory

    cortex

    and

    for

    impulses fromallbrainregionsthatcommunicatewiththecerebralcortex.

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    DIENCEPHALONANDTHEBRAINSTEM

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    y Thehypothalamus,aseriesofbrainnuclei,isthe

    brainsmost

    important visceral

    control

    center.

    y Thehypothalamus regulatessleepcycles,hunger,thirst,bodytemperature,secretionbythepituitarygland,theautonomic nervoussystem,andsomeemotionsandbehaviors.

    y

    The

    small

    epithalamus

    contains

    the

    pineal

    gland,

    whichsecretesa hormonecalledmelatoninthatisinvolvedinthenighttimestageof thesleepwake

    cycle.

    DIENCEPHALON

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    DIENCEPHALON

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    DIENCEPHALON(THALAMUS)

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    BRAINSTEMy Thethreebasicsubdivisionofbrainstemare:

    y Midbrain (Mesencephalon)

    y Pontine(Pons)

    y

    Medulla

    oblongata

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    Ventralofthebrainshowingthethreepartsofthebrainstem:medullaolblongata,ponsandmidbrain

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    BRAINSTEM

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    BRAINSTEM(MESENCEPHALON)y Themidbrainisdividedintoatectum andpaired

    cerebralpeduncles, withthelattercontainingthepyramidalmotortractsinthe crus cerebri.

    y Inthe

    tectum,

    the

    superior

    and

    inferior

    colliculi

    mediate visualandauditoryreflexes.

    y Therednucleusandsubstantia nigra participatein

    motorfunctions.

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    BRAINSTEM(MESENCEPHALON)y Theperiaqueductalgraymatter elicitsthefear

    response.

    y Themidbrainalsocontainsmotornuclei ofcranial

    nervesIII

    and

    IV,

    nerves

    that

    control

    eye

    muscles.

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    BRAINSTEM(PONTINE)y Inthepons,nucleiofcranialnervesVVIIlienearthe

    fourthventricle.

    y Theventralregionoftheponscontainsthepyramidaltracts plusthepontinenucleithatprojecttothecerebellum.

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    BRAINSTEM

    (PONTINE)

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    BRAINSTEM(MEDULLAOBLONGATA)y Themedullaoblongatacontainsthepyramidsand

    theirdecussation, all

    formed

    by

    the

    pyramidal

    tracts.

    Theolivescontainrelaynucleito thecerebellum.

    y NucleiofcranialnervesVIIIXIIlienearthefourthventricle.

    y Centersinthemedullaryreticularformationregulate

    respiration, heart

    rate,

    blood

    pressure,

    and

    other

    visceralfunctions.

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    BRAINSTEM(MEDULLAOBLONGATA)

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    CEREBELLUMy Thecerebellumsmoothsandcoordinatesbody

    movementsand helps

    maintain

    posture

    and

    equilibrium.

    y Itsmaindivisionsthe pairedcerebellarhemispheresand

    the

    vermisare

    divided

    transversely into

    three

    lobes:anterior,posterior,andflocculonodular.

    y

    The

    cerebellar

    surface

    is

    covered

    with

    folia

    (ridges)

    and

    fissures.

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    y Fromsuperficialtodeep,themainregionsofthe

    cerebellumare the

    cortex,

    the

    arbor

    vitae,

    and

    the

    deepcerebellarnuclei.

    y Thecerebellumconnectstothebrainstembythesuperior,

    middle, and

    inferior

    cerebellar

    peduncles,

    thickfibertractsthatcarryinformation toandfromthecerebellum.Allthesefibersareipsilateral.

    CEREBELLUM

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    CEREBELLUM

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    VasculatureofBrainy Thebloodsupplytothebrainisfromtheinternal

    carotidand vertebral

    arteries.

    y Theinternalcarotidarteriesariseintheneckfromthecommoncarotidarteriesandenterthecranialcavitywith

    the

    carotid

    plexus

    of sympathetic

    nerves

    through

    thecarotidcanals.

    y

    The

    terminal

    branches

    of

    the

    internal

    carotids

    are

    the

    anterior andmiddlecerebralarteries.

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    CircleofWillis

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    CircleofWillisy Acircularanastomosisformedby:

    y Theposterior

    communicating

    arteries

    y Theosteriorcerebralarteries

    y Theanteriorcerebralarteries

    y Theanteriorcommunicatingarteries

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    CircleofWillis

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    VENTRICULARSYSTEMANDCEREBROSPINALFLUID(CSF)

    y

    Thereare

    four

    ventricle

    in

    the

    brain:

    y Thetwolateralventriclesareinthecerebralhemispheres

    y The third ventricleis

    in

    the diencephalon; the

    cerebral

    aqueductisinthe midbrain;and

    y The fourthventricleisintheponsandmedullaregions

    ofthe

    brain

    stem.

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    Ventriclesofthebrain

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    References:

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