Necrotizing Sialometaplasia: Case Report Focusing on Histological Stage And Histopathogenesis
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Transcript of Necrotizing Sialometaplasia: Case Report Focusing on Histological Stage And Histopathogenesis
ORAL AND MAXILLOFACIAL PATHOLOGY OOOO
e174 Abstracts February 2014
and fibro-osseous dysplasia for the lesion involving the pre-molars. Microscopically, the molar lesion showed fibrous con-nective tissue with a capsular aspect, hemorrhagic areas,trabecular bone, and some cells with round nuclei and other withfusiform nuclei. Histopathological evaluation confirmed a diag-nosis of aneurysmal bone cyst associated with ossifying fibroma.Microscopically the premolar lesion had the deposition of bonematrix, some cells with round nuclei, and others with fusiformnuclei. Histopathological analysis established a diagnosis ofossifying fibroma. Supported by CNPq:133509/2012-5.
PE-217 - MULTIPLE HEPATIC ABSCESSES CAUSED BYORAL INFECTION: CASE REPORT. RAFAELA MAIACARDOSO ALMENDRA, VIVIANE ALMEIDA SARMENTO,PATRÍCIA LEITE RIBEIRO LAMBERTI, ANTONIOFERNANDO PEREIRA FALCÃO, VINÍCIUS RABELLOTORREGROSSA, VINÍCIUS DA COSTA VIEIRA, ANDRÉLUCAS D’ALMEIDA LYRIO DOS SANTOS. UFBA.
Abscesses in organs are rare and potentially fatal disorders,especially when caused by oral infections such as periodontitisthrough hematogenous spread. Immediate recognition of the mainfocus is important for early treatment of the underlying cause.Woman, 64, was admitted to the University Hospital with signs ofabdominal distention, fever, and vomiting. The diagnosis wasmultiple hepatic abscesses based on cerebral and abdominalcomputed tomography, and severe periodontal disease, indicatedby hepatic drainage and multiple extractions. Blood analysis andliver puncture revealed the presence of Pseudomonas aeruginosa,a bacterial organism found in the oral cavity of hospitalized pa-tients with poor oral hygiene, representing a risk factor for thedevelopment of hepatic abscesses.
PE-218 - MULTIPLE ORAL LYMPHOEPITHELIAL CYSTSIN A HEALTHY PATIENT. STHEFANE GOMES FEITOSA,FILIPE NOBRE CHAVES, FRANCISCO SAMUELRODRIGUES CARVALHO, ANA PAULA NEGREIROSNUNES ALVES, FABRÍCIO BITU SOUSA, FÁBIO WILDSONGURGEL COSTA, KARUZA MARIA ALVES PEREIRA. UNI-VERSIDADE FEDERAL DO CEARÁ CAMPUS SOBRAL.
Oral lymphoepithelial cyst (LEC) is a rare lesion that maydevelop in normal or accessory lymphoid tissue. Typically, it ischaracterized by a solitary, freely movable, dome-shaped, sub-mucosal nodule, with a smooth, nonulcerated surface that isyellowish pink to white, with a cheeselike consistency whenpalpated. A rare case of multiple LEC on the tongue was reported.Woman, approximately 50, complained of three lesions in the oralcavity. Intraoral examination showed three yellowish nodules onthe ventral surface of the tongue. Following biopsy, microscopicevaluation disclosed a diagnosis of LEC. After 1 year of follow-up, no evidence of recurrence was observed. This case addressed arare presentation of oral LEC. To the best of our knowledge, thereare no similar cases published in the English language literature.
PE-219 - MYOFIBROMA IN CHILDHOOD: CASEREPORT. MARCIA RODRIGUES GORISCH, ROSANAMARA GIORDANO DE BARROS, EDUARDO GIORDANODE BARROS, SILVIA ROBERTA CIESLAK. FACULDADEDE ODONTOLOGIA DA UFMS.
Considered to be a rare neoplasm of fusiform cells, myofi-broma occurs more frequently during childhood at multiple sitessuch as bones, intestines, and soft tissues. Reportedly it has adiscrete predilection for the head and neck regions. The jaw is the
most common oral location, followed by the lips, cheeks, andtongue. Myofibroma can grow quickly and is painless. Child, 5,was brought to the Odontology Faculty/UFMS with a nodularlesion of the gingival mucosa whose color was apparently normal.Microscopic evaluation showed fusiform cells lying in order be-tween collagen sheafs. Immunohistochemical reaction was posi-tive to anti-actin antibody of smooth muscle. The treatment ofchoice is surgical excision; recurrence can occur in about 25% ofcases. Although it is considered a benign fibrous neoplasm, sol-itary tumors located in the intestines carry a grim prognosis and a76% mortality rate.
PE-220 - NASOPALATINE CYST: CASE REPORT WITHSURGICAL MANAGEMENT. SERGIO EDUARDOMIGLIORINI, LUCIANO LAURIA DIB, DANIELA LATUFFCORTIZO, MARISA ALVAREZ CORAZZA MARQUES,LUIZ FERNANDO DUARTE, RENATA TUCCI, RICARDOSOUZA. UNIVERSIDADE PAULISTA-UNIP.
Nasopalatine duct cyst is considered a nonodontogenic cystof uncertain pathogenesis that affects individuals between thesecond and fifth decades of life, displaying slow, asymptomaticgrowth. Radiographically there is a radiolucent area in the ante-rior maxilla. Man, 24, came to the clinic of Stomatology GraduateDentistry UNIP for the treatment of a radiolucent lesion, near theapices of the teeth #21, #22, and #23. The vitality test was pos-itive in all dental elements. Computed tomography revealed ahypodense circular-shaped lesion with regular contour andinterruption of the cortical bony palate, buccal area, and nasalcavity floor. Based on a clinical diagnosis of nasopalatine cyst,the patient underwent surgery. Histopathological analysis of thespecimen was done by the service of Oral Pathology FOUNIP.The patient is free of symptoms. Bone formation is evaluatedperiodically by panoramic radiography.
PE-221 - NECROTIZING SIALOMETAPLASIA OF THEINFERIOR LIP: CASE REPORT AND CONSERVATIVEMANAGEMENT. ELOÁ BORGES LUNA, MARIA ELISARANGEL JANINI, VALDIR MEIRELLES JUNIOR, JULIANATRISTÃO WERNECK, RAPHAELLA POSTORIVO, JOSÉALEXANDRE DE ROCHA CURVELLO, MICHELLEAGOSTINI. FACULDADE DE ODONTOLOGIA DA UFRJ.
Necrotizing sialometaplasia is a self-limited inflammatorycondition that affects the minor salivary glands and rarely the lipregion. Often the clinical appearance is similar to that of squamouscell carcinoma (SCC). Man, 65, was referred to the service with alesion in the lip after trauma that did not heal for 15 days. Clinicalexamination revealed an ulcer on the right lower lip that was hardand well-defined, with a grey-white pseudomembrane and symp-toms of burning. The differential diagnoses were lymphoma, SCC,and necrotizing sialometaplasia. Conservative treatment was un-dertaken with topical corticosteroids and cleansing with hydrogenperoxide. In 2 weeks the hardness completely disappeared; after 5weeks of the same therapy, the lesion resolved totally. Because thenecrotizing sialometaplasia is a self-limiting lesion, which healsafter 6 to 10 weeks, we opted for conservative therapy rather thansubmit the patient to an unnecessary invasive procedure.
PE-222 - NECROTIZING SIALOMETAPLASIA: CASEREPORT FOCUSING ON HISTOLOGICAL STAGE ANDHISTOPATHOGENESIS. JOABE DOS SANTOS PEREIRA,BÁRBARA VANESSA DE BRITO MONTEIRO, THÂMARAMANOELA MARINHO BEZERRA, ADRIANO ROCHA
OOOO ABSTRACTS
Volume 117, Number 2 Abstracts e175
GERMANO, GIORDANO BRUNO PAIVA CAMPOS, ANAMIRYAM COSTA DE MEDEIROS, MÁRCIA CRISTINA DACOSTA MIGUEL. UNIVERSIDADE FEDERAL DO RIOGRANDE DO NORTE.
Necrotizing sialometaplasia is a benign, self-limiting in-flammatory condition first described in 1973. Its clinical andhistologic features mimic those of a malignant neoplasm, mainlymucoepidermoid carcinoma or squamous cell carcinoma. A casedescription focused on histologic stage and histopathogenesis ofthe lesion. Man, 26, presented an ulcerated mass in the soft palate.The lesion had appeared 40 days previously and was reddish,firm, and painless, measuring 0.5 cm in diameter. No secondarysignals or lymphadenopathy was present. The clinical diagnosiswas traumatic ulcer. Histopathological examination revealedscarce necrosis of the glandular acini, squamous metaplasia of thesalivary ductal epithelium, pseudoepitheliomatous hyperplasia ofthe overlying epithelium, and an associated inflammatoryresponse. This case demonstrates principally the reparative his-tological stage proposed by Anneroth and Hasen (1982): meta-plastic change of ducts, fibrosis, and chronic inflammatoryinfiltrate. Pathophysiology of this lesion is related to ischemicevents. Its accurate recognition avoids inappropriate treatment.
PE-223 - NEUROFIBROMA IN THE TONGUE: CASEREPORT. JOSÉ NARCISO ROSA ASSUNÇÃO JUNIOR,JOSÉ NARCISO ROSA ASSUNÇÃO JUNIOR, JORGE DESÁ BARBOSA, HAROLDO ARID SOARES, NELISEALEXANDRE DA SILVA LASCANE, DECIO DOS SANTOSPINTO JUNIOR, CELSO AUGUSTO LEMOS JUNIOR. UNI-VERSIDADE METROPOLITANA DE SANTOS/FACULDADEDE ODONTOLOGIA DA USP.
Caucasian woman, 64, demonstrated a tongue lesion that haddeveloped over 8 months. She reported local trauma with asymp-tomatic slow growth of a nodule. Intraoral examination showed anencapsulated submucosal nodule, measuring 1 cm in diameter,which was asymptomatic on palpation; the surface mucosa wasreddish and smooth. The clinical diagnosis was neuroma X lipoma.After the excisional biopsy, histological examination revealed amucosal fragment lined by stratified squamous epithelium and aparakeratinized area of dense connective tissue showing thickbundles of collagen fibers distributed parallel to the epithelium,with a proliferation of bundles of spindle cells in various directions,often with corrugated nuclei. There were also various stromal cellswith eosinophilic cytoplasm resembling mast cells. The resultsuggested neurofibroma. The patient remains asymptomatic withno signs of recurrence after 1 year of follow-up.
PE-224 - NON-FAMILIAL CHERUBISM ASSOCIATEDWITH CONGENITAL CARDIOPATHY: DIFFERENTIALDIAGNOSIS WITH NOONAN SYNDROME ANDTURNER SYNDROME. ARTHUR PIAS SALGUEIRO,RONAIRO ZAIOSC TURCHIELLO, MICHELE RORATOSAGRILLO, MÁRCIA RODRIGUES PAYERAS, LEANDROBERNI OSÓRIO, KÍVIA LINHARES FERRAZZO. FRAN-CISCAN UNIVERSITY CENTER - UNIFRA - SANTA MARIA/RS, BRAZIL.
Cherubism is a rare disease that usually manifests in child-hood. A case of cherubism was reported and the clinical, radio-graphic, and laboratory findings noted, focusing on thedifferential diagnosis. Girl, 10, was brought for dental care with amedical history of pulmonary valve stenosis, short stature, andbilateral convergent strabismus. Physical examination, imaging
findings, laboratory tests, and histology suggested the diagnosisof cherubism. Given the heart disease, a differential diagnosis ofcherubism with Noonan syndrome (NS) and Turner syndrome(TS) was postulated. After normal cytogenetic examination, TSwas ruled out. Based on the clinical diagnostic criteria proposedby Van der Burgt et al (1994), the diagnosis of NS was notpossible. For the differential diagnosis of cherubism, it is neces-sary to unite medical history, physical evaluation, radiographicfindings, and laboratory tests. Although clinical criteria are usefulin the diagnosis of NS, genetic tests are essential to establish thedefinitive diagnosis of this disease.
PE-225 - NON-HODGKIN’S LYMPHOMA IN THE SUB-MANDIBULAR REGION. LEONARDO AMARAL DOSREIS, ALÍCIA RUMAYOR PIÑA, MARISOL MARTINEZMARTINEZ, NÁDIA LAGES LIMA, JOÃO LUIZ DEMIRANDA, OSLEI PAES DE ALMEIDA, ANA TEREZINHAMARQUES MESQUITA. UNIVERSIDADE FEDERAL DOSVALES DO JEQUITINHONHA E MUCURI.
The diffuse large B-cell lymphoma (DLBCL) is the mostcommon type of non-Hodgkin’s lymphoma and is more frequentin the head and neck region. Man, 58, had swelling in the rightsubmandibular region that had developed over 4 months. Hismedical history was uneventful. Extraoral examination revealed anodular lesion, normal in color, with ill-defined borders, that wasadhering to the underlying tissues. Intraoral examination andpanoramic radiograph showed normal features. Histopathologicalanalysis revealed malignancy of lymphocytic origin and demon-strated cells of varied morphologies, some large cells withpolymorphic nuclei, and atypical mitosis. Immunohistochemicalanalysis showed the atypical cells were positive for LCA, CD20,CD43, CD45RO, and CD79a, but negative for CD3, CD138,kappa, and lambda. Ki-67 proliferation index was 60%. Thedefinitive diagnosis was diffuse large B-cell lymphoma. The pa-tient was referred for treatment and is under follow-up.
PE-226 - NOONAN SYNDROME AND ITS DENTOFA-CIAL ACCOMPANIMENTS: REPORT OF TWO CLIN-ICAL CASES. CAROLINE FARIAS LEMOS, LUCIANADUARTE CALDAS, BERNARDO FERREIRA BRASILEIRO,MARTA RABELLO PIVA. UNIVERSIDADE FEDERAL DESERGIPE.
Noonan syndrome (NS) is an autosomal dominant geneticsyndrome that affects both genders, with an incidence estimatedbetween 1:1000 and 1:2500. NS is an important differentialdiagnosis in patients with short stature, facial dysmorphism,delayed puberty, and cryptorchidism. Among the facial changestypical of NS carriers are hypertelorism of the eye, eyelid ptosis,palpebral fissure externally diverted down with low attachment,incomplete rotation of the ear, mandibular micrognathia, shortand webbed neck, and a triangularly shaped face. Changes pro-duced include dental maxillary atresia, making an adequatetongue position and triggering, usually a posterior cross-bite andeventually an anterior open bite. By virtue of mandibularmicrognathia, such patients have malocclusions of type Class IImalocclusion. Two patients with NS demonstrated similarities indentofacial changes and the therapeutic procedures employed.
PE-227 - OCCURRENCE OF ORAL SQUAMOUS CELLCARCINOMA IN A YOUNG PATIENT: CASEREPORT. MATEUS BARROS CAVALCANTE, CAMILAMARIA BEDER RIBEIRO, SONIA MARIA SOARES