Neck Mass Pop

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    ProblemProblem--base learningbase learning

    Neck MassNeck Mass

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    CaseCase : 40

    .

    ChiefComplaint : 4

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    Present illness

    4 PTA

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    Past history

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    MoreHistory ?

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    PhysicalPhysical

    examinationexamination

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    Physical examinationPhysical examination

    GAGA::AA thaithai female, good consciousness,female, good consciousness,notnot pale,nopale,no jaundicejaundice

    Vital signs :Vital signs :

    BT =BT = 3737..22 00CC BP =BP = 120120//8080 mmHgmmHg

    RR =RR = 1616/min/min PRPR== 8484 bpmbpm

    Heart & lungHeart & lung :: normalnormal

    AbdomenAbdomen :: liver and spleen cant beliver and spleen cant bepalpatedpalpated

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    ENT examENT exam

    NoseNose : normal: normal

    NasopharynxNasopharynx : no polyp , no mass seen,: no polyp , no mass seen,nono discharge, not injected,discharge, not injected, notnot swellingswelling

    OropharynxOropharynx : tonsil arent enlarged, dental: tonsil arent enlarged, dental caries,caries,nono ulcer, not injected ,ulcer, not injected ,nono swellingswelling

    IDLIDL : vocal cord normal movement,: vocal cord normal movement,no noduleno nodule , not injected, not injected

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    NeckExaminationNeckExamination

    Thyroid gland not enlargementThyroid gland not enlargement

    Parotid glandParotid gland normalnormal

    Neck mass: (more info next slide)Neck mass: (more info next slide)

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    Positive findingPositive finding

    HxHx::

    44 PTAPTA

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    Positive findingPositive finding

    PE.PE.

    Neck mass :Neck mass :At posterior triangle, irregular surface,

    firm, not tender, movable, no sign of inflammation,

    no translucency

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    Mass :

    - posterior triangle

    - irregular surface- firm

    - not tender

    - movable

    - no sign of inflammation- no translucency

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    Approach to neck massApproach to neck mass

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    Neck massNeck mass

    IncidenceIncidence

    AgeAge

    SexSex Duration (Rule of seven)Duration (Rule of seven)

    PainPain

    General symptomsGeneral symptoms

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    EtiologyEtiology

    0-15 years 16-40 years >40 years

    Inflammatory Inflammatory Malignant

    Congenital

    developmental

    Congenital

    developmentalBenign

    Neoplasm-

    malignant Neoplasm-benign Inflammatory

    Benign MalignantCongenital

    developmental

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    Medical Student Gr. 5A

    Rule ofRule of 8080ss

    Older thanOlder than 4040 yearsyears oldold

    8080% of all% of all nonthyroidnonthyroid neck masses areneck masses are neoplasticneoplastic

    8080%of these

    %of these neoplasmsneoplasms are malignantare malignant

    8080% of these malignant lesions are metastatic lesions% of these malignant lesions are metastatic lesions

    8080% of these metastatic lesions arise from primaries% of these metastatic lesions arise from primaries

    that are above the claviclethat are above the clavicle

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    History of cancerHistory of cancer

    ,,,, 44-- 66

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    Physical examinationPhysical examination

    Local examinationLocal examination

    Regional examinationRegional examination

    General examinationGeneral examination

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    Local examinationLocal examination

    Location (midline or lateral)Location (midline or lateral)

    SizeSize

    ShapeShape SurfaceSurface

    ConsistencyConsistency

    TendernessTenderness MobilityMobility

    PulsationPulsation

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    Midline massMidline mass

    ThyroglossalThyroglossal duct cystduct cyst

    Isthmus of thyroidIsthmus of thyroid

    Pharyngeal pouchPharyngeal pouch SubhyoidSubhyoid bursabursa

    DelphianDelphian nodenode

    LaryngoceleLaryngocele Ectopic thyroidEctopic thyroid

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    Lateral neck massLateral neck mass

    NonNon--lymph nodelymph node

    Lymph nodeLymph node

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    NonNon--lymph nodelymph node

    Solitary thyroid noduleSolitary thyroid nodule

    Branchial cleft anomaliesBranchial cleft anomalies

    Cystic hygromaCystic hygroma Carotid body tumorCarotid body tumor

    LipomaLipoma

    NeurilemmomaNeurilemmoma Swelling of salivary glandSwelling of salivary gland

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    Lymph nodeLymph node

    InfectionInfection

    --acute (pyogenic)acute (pyogenic)

    --chronic (Tuberculosis,atypicalchronic (Tuberculosis,atypicalmycobacterium,cat scrath fever)mycobacterium,cat scrath fever)

    Primary neoplasmPrimary neoplasm

    -- Hodgkins lymphomaHodgkins lymphoma-- NonNon--HodgkinsHodgkins

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    Lymph nodeLymph node

    Metastatic nodeMetastatic node

    -- Head and neck cancerHead and neck cancer

    -- BelowBelow clavicularclavicular cancer (cancer (lung,GI,etclung,GI,etc.).)-- Unknown primaryUnknown primary

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    Lymph node drainageLymph node drainage

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    Cervical node region and possible origin

    of primary neoplasm

    Lymph node Primary

    Submandibular

    Posterior cervical

    Supraclavicular

    Upper jugular

    Middlejugular

    Low jugular

    Lower lip,floor of mouth,tongue

    (anterior),Tonsil,buccal mucosa,gingiva

    Nasopharynx,thyroid,lateral pharyngeal wall

    Below the clavicle

    Tongue(lateral and posterior),palate,tonsil

    Pharynx,larynx,piriform sinus,thyroid

    Esophagus (cervical segment)

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    InvestigationInvestigation

    CBCCBC

    Chest XChest X--rayray

    FlexibleFlexible rhinolaryngoscoperhinolaryngoscope,, nasopharyngoscopenasopharyngoscope UltrasonographyUltrasonography

    DirectDirect laryngoscope,bronchoscopelaryngoscope,bronchoscope,,

    esophagoscopeesophagoscope

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    InvestigationInvestigation

    Fine needle aspirationFine needle aspiration

    Sialography,MRISialography,MRI

    BiopsyBiopsy Syphilis,AIDSSyphilis,AIDS

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    Diffential diagnosisDiffential diagnosis

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    Diffential diagnosisDiffential diagnosis

    Lymphoma ( primary neoplasm )Lymphoma ( primary neoplasm )

    TuberculousTuberculous lymphadenitislymphadenitis

    Metastatic lymph node neoplasmMetastatic lymph node neoplasm LipomaLipoma

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    lymphomalymphoma

    NonNon--hodgkinshodgkins ProgressiveProgressive clonalclonal expansion Bexpansion B--cell , Tcell , T--cell , NKcell , NK

    m/c hematopoietic neoplasm (m/c hematopoietic neoplasm ( 55 times of HD )times of HD ) PainlessPainless adenopathyadenopathy , fatigue and weakness, fatigue and weakness

    B symptoms : fever , night sweat , lost weightB symptoms : fever , night sweat , lost weight

    HepatosplenomegalyHepatosplenomegaly Noncontiguous pattern of spreadingNoncontiguous pattern of spreading

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    Hodgkins diseaseHodgkins disease

    Predominant BPredominant B--cellcell malinancymalinancy

    Bimodal age distribution :Bimodal age distribution : 33rd decade , aroundrd decade , around 6060

    Common present with cervicalCommon present with cervical adenopathyadenopathy B symptom ,B symptom , pruritispruritis ,, hepatosplenomegalyhepatosplenomegaly ,,

    PelPel EbsteinEbstein fever , Alcoholfever , Alcohol--induced pain ( rareinduced pain ( rare

    butbut hignhign specificity )specificity ) contiguous pattern of spreadingcontiguous pattern of spreading

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    TuberculousTuberculous lymphadenitislymphadenitis

    m/c site : neck along them/c site : neck along the sternocleidomastoidsternocleidomastoid m.m.

    , posterior cervical and, posterior cervical and supraclavicularsupraclavicular sites.sites.

    The most common presentation ofThe most common presentation ofextrapulmonaryextrapulmonary tuberculosistuberculosis

    Painless , Advanced may suppurate and form aPainless , Advanced may suppurate and form a

    drainagedrainage particularly frequent among HIVparticularly frequent among HIV--infectedinfected

    patientspatients

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    lipomalipoma

    BenignBenignAll age m/c adultAll age m/c adult

    Soft , not tenderSoft , not tender

    slippery , not attach to skinslippery , not attach to skin

    Vary of sizeVary of size

    Solitary nodule is commonSolitary nodule is common

    Treatment : conservative except tender or rapidTreatment : conservative except tender or rapid

    growth (growth ( SxSx common for cosmetics ) ,common for cosmetics ) ,

    liposuctionliposuction recurrentrecurrent

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    InvestigationInvestigation

    investigateinvestigate

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    InvestigationInvestigation

    CBCCBC

    Chest X rayChest X ray

    FNABFNAB

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    HbHb 1111..99 g/dL , Hctg/dL , Hct 3434..33%%

    WBC countWBC count 99,,500500//LL WBC differentialWBC differential

    NeutrophilNeutrophil 6363 %%

    LymphocyteLymphocyte 3232 %% Atypical LymphocyteAtypical Lymphocyte 22%%

    MonocyteMonocyte 22 %%

    RBCRBC 55..33 xx 101066 //LL PleteletPletelet 350350,,000000//LL Normocytic normochromic RBCNormocytic normochromic RBC

    CBCCBC

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    Chest XChest X--rayray

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    FNAFNA

    Moderate amount of small matureModerate amount of small mature

    lymphocytelymphocyte

    A few plasma cellA few plasma cell

    No evidence of malignancy seenNo evidence of malignancy seen

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    Manageme

    nt

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    Neck mass

    Hx & PEENT exam

    Biopsy

    CXRCBCFNA

    -

    +

    +

    -

    Panendoscope

    Biopsy 4-5 points+ Nasopharynx exam , biopsy

    PF

    BOT

    Supraglottis

    Tonsils

    -

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    -

    PanendoscopeBiopsy 4-5 points

    + Nasopharynx exam , biopsy

    Unknown 10

    Open biopsy

    + frozen Section

    + Radical neck dissection , chemo

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    Management nextManagement next

    Excisional biopsyExcisional biopsy

    Management

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    ExcisionalExcisional biopsybiopsy

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    Pathology finding : 4xPathology finding : 4x

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    Pathology finding :Pathology finding : 1010xx

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    Pathology finding 40xPathology finding 40x

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    Pathology findingPathology finding 4040xx

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    Whats definite diagnosis?Whats definite diagnosis?

    Tuberculous lymphadenitisTuberculous lymphadenitis

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    TreatmentTreatment

    Anti TB drugsAnti TB drugs

    Supportive treatmentSupportive treatment educationeducation

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    TheEnd.Thank for yourattention

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    QuestionQuestion

    11.. midlinemidlineneck massneck mass 33 lateral neck masslateral neck mass 33

    22..neck massneck mass

    ((congenital,infection,trauma,tumorcongenital,infection,trauma,tumor

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    QuestionQuestion 33..malignancymalignancy

    44.Investigation.Investigation

    55..malignancymalignancyexcisionalexcisionalbiopsybiopsy biopsybiopsyprimary lesionprimary lesion