NCIP 2019 - NCIPNCIP

rd3 National Conference of Institute of Pharmacy (NCIP) - 2019

“Integrating Natural and Modern Medicines in Drug Discovery and Development”

NCIP 2019NCIP 2019

January 24 - 25, 2019

ORGANIZED BYInstitute of Pharmacy, Nirma University

S. G. Highway, Chharodi, Ahmedabad – 382481, Gujarat, INDIAPhone : +91-079-3062715 • Fax : +91-2717-241916 • Website : http://www.ncip.in

Supported by:

MISSION

Nirma University emphasizes the all-round

development of its students. It aims at

producing not only good professionals, but also

good and worthy citizens of a great country,

aiding in its overall progress and development.

It endeavors to treat every student as an

individual, to recognize their potential and to

ensure that they receive the best preparation

and training for achieving their career

ambitions and life goals.

VISION

Shaping a better future for mankind

by developing effective and socially

responsible individuals and

organizations

QUALITY STATEMENT

To develop high quality professionals who reflect and demonstrate values that the University stands

for, through innovation and continuous improvement in facilitation of learning, research and

extension activities.

I

II

rd3 National Conference of Institute of Pharmacy

We are heartily thankful to

Science and Engineering Research BoardDepartment of Science and Technology

Department of Biotechnology

Defence Research and Development Organisation

Gujarat Council on Science and Technology

Shri Nitinbhai PatelDy. Chief Minister of Gujarat


III

Shri Bhupendrasinh ChudasamaEducation Minister,

Government of Gujarat


IV

Prof. B. SureshPresident,

Pharmacy Council of India

V


Vaidya Rajesh KotechaSecretary, AYUSH


VI


VII

Shri K. K. PatelVice-

Nirma UniversityPresident,

MESSAGE

I am gratified to welcome all invited guests and participants at Nirma University for

National Conference of Institute of Pharmacy (NCIP – 2019) on “Integrating

Natural and Modern Medicines in Drug Discovery and Development” from

January 24-25, 2017.

All the diseases are different and unique, require different drugs for treatment.

Research is the best defense against all the challenges faced in development of safe

and efficacious treatment of diseases. Currently, the nation’s investment in drug

development is also increasing which is definitely helping the young researchers for

new drug development by integrating natural and modern medicines.

In light of this, organization of such a conference will serve the purpose of nurturing

innovations in the field of drug, discovery & development and help in exchange of

research ideas amongst the budding scientists from academia and industries.

I heartily acknowledge the efforts of Institute of Pharmacy, Nirma University for

organizing such event that provides a common platform for all stakeholders to put

forward their views and opinions. I extend my best compliments to Institute of

Pharmacy for a grand success of this conference and we hope that the Institute

continues to fill the void in the pharmaceutical sector by arranging many more

conferences and workshops in future.

Dr. Anup K. SinghDirector GeneralNirma University


VIII

MESSAGE

I am delighted to learn that Institute of Pharmacy, Nirma University is organizing a National Conference for the third time - National Conference of Institute of Pharmacy (NCIP – 2019) on “Integrating Natural and Modern Medicines in Drug Discovery and Development” from January 24-25, 2019. It’s my honor and privilege to welcome all the eminent speakers and delegates to the exquisite campus of Nirma University, Ahmedabad.

Designing new leads against various life threatening diseases has been an integral part of drug discovery process. New drug discovery is facing serious challenges due to reduction in success rats of new chemical entities as well as excessive high cost. This scenario has prompted researchers to come out with a novel approach of integrated drug discovery. Combining the principles of natural medicines with refined modern chemical technology can help in the development of more economical, environmental friendly and effective drug discovery process. Such conferences will help spread the awareness as well as a stage to discuss all the global isssues in integrating Natural and Modern Medicines in Drug Discovery and Development.

I appreciate the efforts of Institute of Pharmacy for taking lead in fostering innovations in drug discovery by organizing a conference on such sought after theme and to offer common platform for the researchers from various parts of the country. I wish from the bottom of my heart that this conference serves as a medium to bring together eminent personalities across the nation to share their experience in the field of drug discovery and innovation.

I once again welcome all the dignitaries, delegates and participants at Nirma University for the conference and wish Institute of Pharmacy to have a grand and successful event.

CONTENTS

SR. TITLE PAGE

No. NO.

1 About Nirma University & Institute of Pharmacy 03

2 Advisory Committee 10

3 Organizing Committee 11

4 Students Task Force 13

5 Scientific Schedule at a Glance 14

6 Inauguration, Valedictory and Key note address 16

7 Plenary Sessions 21

8 Panel Discussion 33

Institute of Pharmacy, Nirma University

FROM THE DESK OF ORGANIZERS

With the great privilege on behalf of the Organizing Committee, it is our honor to invite all the delegates,

invitees and students to the 3rd National Conference of Institute of Pharmacy (NCIP-2019) on “Integrating

natural and modern medicines in drug discovery and development” to be held during January 24-25, 2019.

The pharmaceutical science is a group of interdisciplinary fields involved in the design, discovery,

development, delivery and disposition of the drugs. With the advent of numerous novel drug discovery and

development techniques, natural medicines still hold great promise to offers holistic approach for better

management of various diseases. Successful Integration Of traditional and evidence based medicine can be

possible with each being separately recognized as legitimate forms of health care within the same framework

and by the combined effort of public and government sector. This integrated approach will help in the

development of more economical and effective therapeutics but at the same time faces numerous

challenges. In view of this, the 3rd National conference is organized with the present theme to provide an

open forum for the academicians, researchers, physicians and professionals of pharmaceutical field to enrich

their knowledge about the cutting edge advances and research related to drug discovery & development by

integration of natural and modern medicines.

The organizing committee, under the valuable support and guidance of management of Nirma University as

well as advisory committee members will be able to give this shape of the conference and ensure you great

learning experience at conference. Discussions will be led by experts from the industries, respectable

academia and health care practitioners through plenary sessions and panel discussion. Poster sessions in

various areas of traditional medicines and pharmaceutical sciences will provide an ideal platform to represent

and exchange the ideas from budding researchers.

We acknowledge financial support received from Department of Biotechnology (DBT), Department of Science

& Technology (DST), Defense Research and Development Organization (DRDO) and Gujarat Council on

Science & Technology (GUJCOST) as well as various industries.

We are deeply thankful to all the resource persons who have travelled far distance to participate and interact

with the young researchers.

All these efforts undertaken by the organizing and technical committees has led to a high quality technical

conference program for all the attendees to add great value in ongoing research in various fields of

pharmaceutical sciences.

Welcome to NCIP 2019 and wish you all a good stay and memorable time in this conference.

We are looking forward for your valuable cooperation and dynamic participation to make this conference a

grand success.

02

Dr. Niyati Acharya

Organizing Secretary, NCIP-2019

Dr. Manjunath Ghate

Convener, NCIP-2019


ABOUT NIRMA UNIVERSITY

03

Nirma University was established by the initiative of the Nirma Education and Research Foundation. The

University was established in the year 2003 as a statutory university under a special act passed by the Gujarat

State Legislative Assembly. It is recognized by the University Grants Commission (UGC) under Section 2 (f) of

the UGC Act. The University is duly accredited by National Assessment and Accreditation Council (NAAC) with

'A' grade. The University is a member of Association of Indian Universities (AIU) and the Association of

Commonwealth Universities (ACU).

Functioning under the aegis of NERF, the University consists of Faculty of Technology and Engineering,

Faculty of Management, Faculty of Pharmacy, Faculty of Law, Faculty of Science, Faculty of Doctoral Studies

and Research, Faculty of Architecture & Planning, Faculty of Commerce and Department of Design.

Innovation, excellence, and quality are the driving forces on the campus and this has translated the vision of

these institutions into a reality over a short period of time. Today the campus vibrates with not only world

class curricular activities but also with myriad activities like international conventions, symposia, conferences,

student competitions, conclaves, short-term industry relevant programs, cultural activities, etc.

The University is identified with cutting edge research, robust academic program, quality teaching learning

process and over-all personality development interventions of its students. The 125 acres sprawling state of

art campus provides refreshing environment and stimulates intellectual growth and creativity.

The University in the year 2015 has been recognized as among the leading Universities in the Country by

India Today. In the year 2018, it has been ranked as the 94th university in India by NIRF India Rankings.

The University has been awarded under the category of 'Excellence in Technology for Education Delivery'

during the FICCI Education Awards 2015, as a part of the Eleventh FICCI Higher Education Summit 2015 held

during November 3-4, 2015 organized by FICCI in association with the Ministry of Human Resource

Development, Government of India.

In addition to above the University has also been accorded recognition as Scientific and Industrial Research

Organization by the Department of Scientific and Industrial Research (DSIR), Department of Science and

Technology, Government of India in 2014.

The seven constituent institutes being run under the faculties are: Institute of Technology, Institute of

Management, Institute of Pharmacy, Institute of Science, Institute of Law, Institute of Architecture & Planning

and Institute of Commerce. The under-graduate, post-graduate and doctoral level programmes offered by

these institutes are rated highly by accreditation agencies, industry, business magazines and students.


Institute of Pharmacy established in the year 2003, is a leading institute in the western region of the country

imparting quality pharmacy education at under graduate, post graduate and doctoral levels. Institute of

Pharmacy, Nirma University has been ranked 18th best pharmacy institute among pharmacy institutions of

the country by National Institutional Ranking Framework, Ministry of Human Resource Development, Govt. of

India.

Institute of Pharmacy prepares the students to meet the challenges in the area of pharmaceutical

manufacturing and research and development. The Institute houses state-of-art research facility and

infrastructure to support pharmaceutical education and research. The Institute offers B. Pharm, M. Pharm and

Full time and External Ph.D. Programmes in Pharmaceutical Sciences. The Institute has adopted Outcome

Based Education (OBE) to further advance the development of professional knowledge, inculcate

employability skills in addition to development of character and social responsibility. To achieve the same

objective, vision & mission of the institute was also defined in line of University's vision & mission. Further,

the programme educational objectives and programme outcomes are also well defined & available on

www.nirmauni.ac.in/ipnu

The Institute has dynamic curriculum, robust and talented pool of faculty members, and state of the art

infrastructure in all the departments. It is well known for imparting quality education, doing active research

and also in nurturing students for holistic development, achieved through students' engagement tools like

continuous evaluation, blended learning, active use of Massive Open Online Course, credit-based systems,

departmental electives, institute electives, university and non-university courses, industrial visits & training,

industrial and hospital projects, expert lectures, special training in communication skills, yoga classes and

many more.

OBJECTIVES :

1. To develop a centre of excellence in imparting graduate, postgraduate, doctoral and postdoctoral level

education in pharmaceutical sciences.

2. To cater to the human resource needs of the rapidly expanding pharmaceutical industry, educational

institutions and research laboratories in Gujarat State and in the country at large.

3. To promote research in high tech emerging and thrust areas of medicine and human healthcare and

contribute towards fulfilling the national objectives in pharmaceutical education and technology.

4. To establish excellent industry academy interactions and undertake collaborative professional

programmes in the areas of pre-clinical toxicity studies, pharmacokinetics and drug metabolism,

formulation and development studies.

5. To undertake research projects sponsored by the government, various funding agencies and the

pharmaceutical industries.

6. To regularly conduct continuing education programmes for the pharmaceutical scientists and

academicians

ABOUT INSTITUTE OF PHARMACY

04


PROGRAMMES OFFERED BY THE INSTITUTE INCLUDE:

1. B. Pharm. (Eight semester programme)*

2. M. Pharm. (Four semester programme)*

a. Pharmaceutics

b. Pharmacology

c. Pharmaceutical Chemistry

d. Regulatory Affairs

e. Pharmaceutical Analysis

3. Ph. D. in Pharmaceutical Sciences (Full time & External)**

*With Industrial Training, **With Course Work

THE CAMPUS

The Institute of Pharmacy is situated on the sprawling 125 acre green campus of Nirma University. It has all

the modern facilities like Sophisticated Instruments, State of the art Labs, Excellent Computing & IT

infrastructure including latest software, Rich Library, canteen, playgrounds, indoor games and gymnasium.

The campus provides an ambience that motivates the students to grow. The Institute building has modern

amenities, with enough space and replenished with modernity and grandeur. The post graduate laboratories

are independently developed for M.Pharm. and Ph.D. students. In addition the campus has sports facilities

and the overall ambience is distinguishable by its serenity, which is conducive for intellectual pursuits.

CLASS ROOMS

The classrooms are spacious, ventilated and equipped with multimedia and audiovisual equipments to

facilitate effective learning. The classrooms are designed to provide maximum interaction between the faculty

and students.

05


COMPUTER CENTRE

The central computer facilities consist of 24 servers and more than 1500 systems, which are interconnected

by fiber optic cables and 256 Mbps, leased line internet connectivity. Computing facilities for students include

a laboratory equipped with 42 computers for U.G. and P.G. students. The students have an easy access to the

internet. The campus is equipped with Wi-Fi network.

LEARNING RESOURCES CENTRE (LIBRARY)

At Institute of Pharmacy, it is a belief to facilitate production and dissemination of knowledge, information,

insights & intellect in all scientific communities. The Library plays a vital role in the collection development

and dissemination of scientific information and includes a wide range of volumes of different branches of

Pharmaceutical Sciences and allied subjects and also provides extensive access to leading Indian and

international research journals.

The Library at Institute of Pharmacy houses more than 9,062 volumes of books selectively chosen for

reading and reference, 365 CDs, 1,835 Bound Volumes, 831 Project Reports (B.Pharm), 540 Research Project

Reports (M.Pharm), 70 PhD Theses and subscribes about 21 printed national, 3 international periodicals, 15

magazines and 9 newspapers. Library is also providing Web access to 113 e-journals: Science Direct:

Pharmacology, Toxicology and Pharmaceutical Sciences Module (89), Bentham Science Publisher (23),

Pharmacological Review and Scopus Database on campus. Library also provides remote log-In facility to

access e-resource 24×7 off the campus.

SOPHISTICATED INSTRUMENTS LABORATORY

The Institute has modern instruments like High Pressure Homogenizer, Particle Size Analyzer and Zeta

Potential Analyzer, Lyophilizer, high speed homogenizer, stereotaxic apparatus, microdialysis system, FT-IR,

Fluorescence Spectrometer, Super Critical Fluid Chromatography, UV-Spectrophotometer, HPLC Binary

Gradient with PDA Detector, HPLC with Autosampler Quaternary Gradient, GC, Supercritical Fluid

Chromatography and Extraction, HPTLC ,PCR, Gel documentation system, data acquisition system and Raman

Spectrophotometer which provide analysis comprising molecular mechanisms, elemental composition,

chromatography, diffraction, particle/ material characteristics including various spectroscopes. The laboratory

provides analytical support and intellectual input to both in-house and externally funded R & D projects.

MACHINE ROOM

The machine room is equipped with Rotary Tablet Machine, Fluidized Bed Drier cum Coater, Digital

Tensiometer, Texture Analyzer, Mini Spray Dryer, Freeze Dryer, Automated Dissolution Apparatus, Projection

Microscope, Vaccum Drier, Ultrasonicator, High Pressure Homogenizer, Particle Size Analyzer etc. The

laboratory provides facilities to carry out extensive research and consultancy for pharmaceutical industries.

ANIMAL HOUSE

The Institute has state-of-art Animal House facility registered by CPCSEA, Government of India. It provides

pre-clinical testing in conformity with national and international regulatory guidelines (Schedule Y and

OECD). The animal house facilitates the availability of healthy and homogeneous animals for U.G. and P.G.

studies and for research / outsourced testing. An incinerator is also available at the Animal House.

06


NIRMA HERBAL WEALTH

A medicinal plants garden, covering a total area of 3556 sq. meters has been developed at the University

campus. More than 150 species of various medicinal plants have already been planted. The medicinal plants

garden provides a strong impetus for herbal drug research and for the training of the students of the

Institute.

RESEARCH LABORATORY

A fully dedicated research laboratory helps the faculty members & research scholars to undertake research

projects as well as to carry out doctoral research work in the areas of dosage form design, stability studies,

phytochemistry, pharmacological screening, synthetic and analytical chemistry and pharmaceutics.

DRUG DISCOVERY LAB

The Institute has a separate Drug Discovery Laboratory equipped with necessary computational facilities. It

possesses seven workstations (computers) with latest configurations. It also possesses molecular modeling

software like Gold Suite 5.1. The students are trained on the software for docking, pharmacophore modelling

and QSAR studies etc.

ACHIEVEMENTS

A team of highly qualified and dedicated faculties are continuously skilled in latest methods of educational

technology and in their respective fields of specialization. Faculty members are actively involved in research,

consultancy and financially funded and sponsored projects.

07


Total 17 recognized Ph.D. guides with more than 65 research scholars are actively working in the diversified

thrust areas of pharmaceutical sciences. Apart from presenting and publishing their work in reputed journals

and conferences, faculty members and students have won laurels for the Institute by publishing of books,

patenting their research work and by receiving many prestigious awards.

The Institute had received more than 4.5 crore rupees grant from various external funding agencies like

GMDC (Ahmedabad), CSIR, ICMR, UGC, DST, AYUSH, GUJCOST, GSBTM, DBT, SAC-ISRO, FIST and BRNS.

Institute has very high intellect faculty members who are actively involved in research, consultancy, testing

and are supported financially with sponsored projects from different government as well as private

organizations.

Many full time PhD research scholars have received the prestigious fellowships from DST-INSPIRE (Innovation

in Science Pursuit for Inspired Research), Women Scientist Fellowship from the DST, Senior Research

Fellowship from ICMR and CSIR, Prime Minister Fellowship Government of India and from Confederation of

Indian Industries (CII).

Many M. Pharm students and research guides from the department of Medicinal Chemistry, Pharmaceutical

Technology & Bio-pharmaceutics, Pharmacology, Pharmacognosy and Pharmaceutical Analysis have received

national recognition for “R. V. Patel Competition for Best Thesis at Masters Program” supported by DST,

Government of India and Troikaa Pharmaceuticals Ltd. Faculty members have been awarded with P. D. Sethi

08


awards, N. S. Dhalla Young Scientist award and APTI awards for publishing the best research papers and

presentations during symposiums and conferences. Faculties received best principal of the year 2017-2018

award and women of the year award from Association of Pharmaceutical Teachers of India (APTI). Faculty

members have contributed in innovative pharmaceutical research by solving web based challenges floated by

the Innocentive. Inc. USA.

The graduate students have been awarded for securing the highest grade in B.Pharm Examinations and

many students performed well to achieve All India rank in GPAT and secured admissions at reputed institutes

like IITs, NIPER and other PG centres of India and also abroad. The post graduate students have been placed

at reputed academic institutions and industries of India.

Different departments of Institute have received support from government organizations like ICMR, DST,

AICTE, ISTE, GUJCOST, DBT, DRDO, INSA and CSIR in organizing various workshops, conferences and

symposia of national and international level on recent advances in pharmaceutical sciences.

COLLABORATION WITH RESEARCH INSTITUTIONS / INDUSTRIES

The University, recognizing research as the main drive of success in an academic setting, has established a

distinct Faculty of Doctoral Studies and Research to initiate research programmes independently or in

collaboration with National Laboratories that have the potential in terms of infrastructure and expertise. As a

beginning such collaboration exists with institutions like-

• Piramal Drug Development Services Ltd., Ahmedabad

• Physical Research Laboratory (PRL), Ahmedabad

• B. V. Patel Pharmaceutical Education and Research Centre, Ahmedabad

• Cadila Pharmaceutical Research Centre, Ahmedabad

• Intas Pharmaceuticals Ltd., Ahmedabad

• Directorate of Forensic Science, Government of Gujarat

• Space Application Centre (ISRO), Ahmedabad

• Ayurlab Herbal Pvt. Ltd., Vadodara

• Appollo Hospitals International Ltd., Ahmedabad

• CII (Confederation of Indian Industry), Ahmedabad

• Beiersdorf (Nivea), Germany

• Eris Life Sciences, Ahmedabad

• Quantys Clinical Pvt Ltd., Gandhidham

• Sushen Medicamentos Pvt Ltd., Ahmedabad

• Chemical Shoppe Pvt Ltd., Ahmedabad

• Indian Institute of Chemical Technology, Hyderabad

• Finecure Pharmaceuticals Limited, Ahmedabad

• Contract Pharmacal Corp. (CPC), Ahmedabad

• Synchron Research Services Pvt Ltd., Ahmedabad

• Massachusetts College of Pharmacy and Health Science (MCPHS) University, Boston, USA.

• Plovdic University, Bulgaria

• Changwon National University, South Korea

• The University of Southern California, Los Angeles, California, USA.

09


ADVISORY COMMITTEE

1. Dr. Anamik Shah, Vice Chancellor, Gujarat Vidhyapith, Ahmedabad

2. Dr. Manish Nivsarkar, Director, B. V. Patel PERD Center, Ahmedabad

3. Dr. Kiran Marthak, Director - Management, Lambda Therapeutic Research Limited, Ahmedabad

4. Dr. Lal Hingorani, CMD, Pharmanza Herbal Health, Dharmaj

5. Dr. Rakesh Rawal, Professor, Department of Life Sciences, Gujarat University, Ahmedabad

6. Mr. S. B. Dangayach, Founder Trustee of Innovative Thought Forum, Ahmedabad

7. Prof. Bhaswat S. Chakraborty, Emeritus Professor, Institute of Pharmacy, Nirma University

10


CHIEF PATRON

VARIOUS COMMITTEES

CONVENER

Scientific & Abstract book

Committee

Prof. Tejal A. Mehta

Dr. Bhoomika M. Patel

Dr. Nagja V. Tripathi

Dr. Nrupesh R. Patel

Ms. Palak K. Parikh

Dr. Mohit P. Shah

Mr. Shreyas Bhuva

Mr. Mukeshbhai Patel

Printing and Souvenir

Committee

Dr. Shital Butani

Dr. Snehal S. Patel

Dr. Bhagwati Saxena

Mr. Jignesh Patel

ORGANIZING COMMITTEE

Shri K. K. Patel

Vice-President, Nirma University

Dr. Anup K. Singh

Director General, Nirma University

Dr. Niyati Acharya

Head, Department of Pharmacognosy, Institute of Pharmacy

Nirma University

Prof. Manjunath D. Ghate

Director

Institute of Pharmacy

Nirma University

ORGANIZING SECRETARY

11


Finance Committee

Prof. Priti J. Mehta

Dr. Bhumika D. Patel

Mr. Dinesh Patel

Mr. Devendrabhai Vaghela

Registration & Correspondence

Prof. Jigna S. Shah

Dr. Shital Panchal

Dr. Charmy S. Kothari

Dr. Vidhi Shah

Ms. Pooja Pandey

Ms. Jigisha Patel

Mr. Chetan Patel

Transport, Accommodation

& Logistics

Dr. Hardik G. Bhatt

Dr. Vivek Vyas

Mr. Shailesh Patel

Venue Management

Dr. Jigar N. Shah

Mr. Mukesh Patel

Mr. Kiran Parmar

Catering

Dr. Mayur M. Patel

Mr. Rohitbhai Patel

Mr. Hasmukhbhai Rathod

Mr. Virendra Goswami

Hospitality & Reception

Dr. Jignasha K. Savjani

Dr. Dipal M. Gandhi

Ms. Drashtiben Patel

Ms. Dhartiben Patel

Website Management

Dr. Dhaivat C. Parikh

Ms. Jaya Dabhi

Media Publicity

Mr. Tushar Patel

Ms. Sima Ahire

12


STUDENTS TASK FORCE

Scientific & Abstract book

Committee

Chetan Dhal

Manan Shah

Tripti Halder

Kirti Vishwakarma

Khushali Parekh

Harshita Gupta

Ankita Mehta (M. Pharm.)

Jigisha Chauhan (M. Pharm.)

Diksha Pandey (M. Pharm.)

Silvi Singh (M. Pharm.)

Shivangi Panchal (M. Pharm.)

Printing and Souvenir committee

Vishal Chavda

Harshita Gupta

Trisha Bhatt (M.Pharm.)

Finance Committee

Dhara Bhayani

Registration & Correspondence

Chintan Pansara

Parmi Patel

Krunal Prajapati

Misari Patel

Priyanshi Shah (M.Pharm.)

Riya Chitral (M.Pharm.)

Vidhi Patel (M.Pharm.)

Swapnil Shah (M.Pharm.)

Jimmy Patel (M.Pharm.)

Vraj Mehta (M.Pharm.)

Transport, Accommodation &

Logistics

Udit Chaube

Namdev Dhas

Piyush Gediya

Arpit Bana

Jaydeep Chavda (M. Pharm.)

Kevin Shah (M.Pharm.)

Venue Management

Vishal Chavda

Jayanta Kumar Maji

Vimal Gupta (M. Pharm.)

Vismay Saraiya (M. Pharm.)

Mitali Thakur (M. Pharm.)

Harshil Shah (M.Pharm.)

Catering

Kartik Hariharan

Hemil Pandit (M.Pharm.)

Harsh Maru (M.Pharm.)

Riyaz Momin (M.Pharm.)

Karanpalsingh Chaudhary (M.Pharm.)

Hospitality & Reception

Kartik Hariharan

Shruti Rawal

Manasi Patel

Dattatreya Yadav

Karan Rathod (M.Pharm.)

Sapana Bhati (M.Pharm.)

Dhruvi Gandhi (M.Pharm.)

Shreya Mehta (M.Pharm.)

Media Publicity

Nisith Raval

13


SCIENTIFIC SCHEDULE OF NCIP-2019 AT A GLANCE

10:00 am to 10:45 am Dr. P. R. Vavia Professor of Pharmaceutics & Dean, Role of excipient functionality in

Academic Programme, Institute of Chemical drug deliveryTechnology, Mumbai

Plenary Lecture-1

2:00 pm to 2:45 pm Dr. Anil K MishraScientist "G", Molecular Imaging and Non-Invasive Imaging Probes Research Centre, Institute of Nuclear for Life ImagingMedicine and Allied Sciences, Delhi

2.45 pm to 3:30 pm Prof. K. S. Laddha Plenary Lecture-3Professor of Pharmacognosy, Integrating herbals into

Institute of Chemical Technology, Mumbai modern medicine

Plenary Lecture-2

3:45 pm to 4:30 pm Dr. Kiran MarthakDirector - Management, Lambda Therapeutic AYUSH and its Regulations

Research Ltd., Ahmedabad and GCP

4:30 pm to 5:15 pm Prof. A. K. Chakraborti Plenary lecture-5Professor and Head, Department of New chemistries in the quest for

Medicinal Chemistry, and Dean, novel anti-inflammatory scaffoldsNational Institute of Pharmaceutical

Education and Research (NIPER), Mohali

Plenary lecture-4

"Integrating natural and modern medicines in drug discovery and development"th th

24 - 25 January, 2019

thDAY 1: 24 JANUARY 2019 (THURSDAY)

9:15 am to 10:00 am Registration and Breakfast

14

Venue: Auditorium, Institute of Management, Nirma University, Ahmedabad

10.45 am to INAUGURATION

12:00 noon Chief Guest: Dr. G . N. Singh

Secretary-cum-Scientific Director, Indian Pharmacopoeia Commission

Ministry of Health & Family Welfare, Govt. of India

Guest of Honour: Dr. Gopal Kundu

Director (I/c), National Centre for Cell Science, Pune

12.00 noon Key Note Address

to 1:00 pm Dr. Gopal Kundu, Director (I/c), National Centre for Cell Science, Pune

Title: Role of Osteopontin In Tumor Microenvironment:

A New Paradigm In Cancer Therapy

1:.00 pm to 2:00 pm Lunch Break

Chairperson: Dr. Gopal Kundu, Director (I/c), NCCS, Pune

3.30 pm to 3.45 pm Tea- Coffee and Networking

Chairperson: Dr. Anil K Mishra, Scientist "G",

Molecular Imaging and Research Centre, INMAS, Delhi


1.15 pm to 2:00 pm Prof. Javed AliProfessor (Pharmaceutics), Nanopharmaceuticals: challenges and

School of Pharmaceutical Education and opportunities for phytotherapeuticsResearch (Formerly Faculty of Pharmacy),

Jamia Hamdard, New Delhi

2:00 pm to 2:45 pm Dr. Jyoti Paliwal Plenary Lecture-9Director, PHAEX Consulting, ADME Studies for Rational Integration

Gurugram of Natural Products and Modern Medicine

Plenary lecture-8

4:00 pm to 5.00 pm VALEDICTORY FUNCTION

Chief Guest: Prof. N. R. Sheth

Vice Chancellor, Gujarat Technological University, Ahmedabad

Guest of Honour: Dr. Anamik Shah

Vice Chancellor, Gujarat Vidyapith, Ahmedabad

5.00 pm onwards Tea- Coffee and Networking

15

Moderator:

Dr. Suresh Patankar, Chairman, Department of Urology, ACE Hospital and Research Center, Pune

Panelist:

Prof. Krishnapriya Mohanraj, Vice Principal (Administration and Strategy)Professor, Department of Pharmaceutical Analysis, Bombay College of Pharmacy, Mumbai

Mr. S. B. Dangayach, Founder Trustee, Innovative Thought Forum, Ahmedabad

Dr. Jyoti Paliwal, Director, PHAEX Consulting, Gurugram

Dr. Rakesh Rawal, Professor, Department of Life Sciences, Gujarat University, Ahmedabad

Dr. Sarat Dalai, Director, Institute of Science, Nirma University, Ahmedabad

Dr. Shivprakash Rathnam, Managing Director, Synchron Research Services Pvt. Ltd., Ahmedabad

9:30 am to 10:15 am Dr. Suresh PatankarChairman, Department of Urology, Lab to patent to patient

ACE Hospital and Research Center, Pune

10:15 am to 11:00 am Prof. Krishnapriya Mohanraj Plenary Lecture-7Vice Principal (Administration and Strategy) Drug Discovery from Natural

Professor, Department of Pharmaceutical Sources- Challenges and Case studiesAnalysis, Bombay College of Pharmacy,

Mumbai

Plenary lecture-6

thDAY 2: 25 JANUARY 2019 (FRIDAY)

9:00 am to 9:30 am Registration and Breakfast

Chairperson: Dr. Bhaswat Chakraborty,

Professor Emeritus, Institute of Pharmacy, Nirma University

11.00am to 12.30pm Poster Session (All tracks) • Venue: Institute of Pharmacy

12.30 pm to 1.15 pm Lunch Break

Chairperson: Dr. Manish Nivsarkar, Director, B. V. Patel PERD Centre

2:45 pm to 3.00 pm Tea- Coffee and Networking

3:00 pm to 4:00 pm PANEL DISCUSSION

Integrating natural and modern medicines in drug development life cycle for

better health outcomes: Need or Mandate?


Inauguration, Valedictory and Key note address

16

Dr. G. N. Singh

Secretary-cum-Scientific Director

Indian Pharmacopoeia Commission

& Former Drugs Controller General (India)

Central Drugs Standard Control Organization (CDSCO)

Ministry of Health & Family Welfare, Govt. of India

BIODATA

Dr. G.N Singh did his doctorate in Pharmaceutical Sciences from Banaras Hindu University in 1987 and MBA

from University of Hull, U.K in the year 1997. He is a man of humble beginning having qualities of excellent

leadership, dedication and commitment to raise the quality of drug regulatory system in the country. Dr. has

got established Indian Pharmacopoeia Commission (IPC) in the year 2009 with aim to set and promote

quality standards for drugs and pharmaceuticals. Dr. G. N. Singh, the first Secretary-cum-Scientific Director of

the Commission has been discharging the functions and duties of Chief Scientific and Executive Officer.

Under his leadership, IPC publishes Indian Pharmacopoeia (IP) and its Addenda at regular time interval,

ensures availability of IP Reference Substances (IPRS) and Impurity standards. The Indian Pharmacopoeial

laboratory is accredited as WHO pre-qualified (first among government laboratories) and NABL accredited to

ensure compliance of ISO:IEC 17025:2005. To promote rational use of drugs, IPC publishes National

Formulary of India (NFI) at regular time intervals. IPC also acts as National Coordinating Centre (NCC) for

Pharmacovigilance programme of India (PvPI) with the aim to monitor the safety of the drugs and devices in

the country. NCC-PvPI works through ADR monitoring centres in the country and also contributes to WHO

Programme for International Drug Monitoring.

Dr. Singh was holding additional charge as Drugs Controller General (India) of the Ministry of Health and

Family Welfare, Govt. of India from 21st February, 2012 to 20th February, 2018. Dr. Singh within the span of 6

years was able to give new directions to the Central Drugs Standard Control Organisation (CDSCO). He was

instrumental in bringing out swift changes in the drug regulatory landscape of the country by means of

simplification of rules, and procedures using cutting-edge technological platforms.

Dr. Singh also served/serving as a member of various national and international committees, to name few-

Drugs Technical Advisory Board, Drugs Consultative Committee, Expert Core Committee of National List of

Essential Medicines, Pharmacy Council of India, Expert Core Committee of National List of Essential Medicines

and Investigational New Drug approval committee etc of Govt. of India and also in advisory boards of various

academic institutions. The United States Pharmacopoeia convention recognized the services of Dr. Singh and

appointed him as voting delegate for Indian Pharmacopoeia Commission in the USP convention. Dr. Singh is

at Research Council of CDRI, Lucknow and IIIM, Jammu of CSIR, New Delhi.

The vision of Dr. Singh is to bridge the gap within the Industry – Academia - National Institutions - Public for

better health care system in India.

17

Chief Guest – Inaugural Function


Role of Osteopontin In Tumor Microenvironment:

A New Paradigm In Cancer Therapy

Dr. Gopal Kundu,

Director (I/C),

National Centre for Cell Science, Pune

BIODATA

Dr. Gopal Kundu has obtained his Ph.D. in chemistry from Bose Institute, Kolkata, India (1989). He did his

post-doctoral research in US from 1989 to 1998. He joined as Scientist-D at National Centre for Cell Science

(NCCS) in 1998 and at present he is Scientist-G. His area of research at NCCS is tumor biology, cancer stem

cells, angiogenesis, cancer therapeutics and nanomedicine. He has received several awards including Fellows

Award for Research Excellence from USA; National Bioscience Award; Shanti Swarup Bhatnagar Prize;

International Award in Oncology, Greece; International Young Investigator Award, USA and 7th National

Grassroots Innovation Award, Rashtrapati Bhavan, India. He is Fellow of National Academy of Sciences and

Indian Academy of Sciences. He has published 81 papers including Nature Medicine, Science, PNAS, Cancer

Research, J. of Invest. Dermatology, JBC, TCB, Oncogene, Nanomedicine etc and one US patent. He serves as

Editorial Board Member of Current Molecular Medicine, Molecular Medicine Reports, American Journal of

Cancer Research and Associate Editor of Molecular Cancer. Dr. Kundu is acting as Visiting Professor at Curtin

University, Perth, Australia. Dr. Kundu is also Director (I/c) at National Centre for Cell Science, Pune.

KEY NOTE ADDRESS

Tumor microenvironment play important role in determining the invasive and metastatic potential of breast

and other cancers. Analysis of microenvironment in patients with different solid tumors reveals that the

majority of tumors showed infiltration of T cells, macrophages, fibroblasts, dendritic cells etc. Intratumoral

heterogeneity contributes significantly to the effectiveness of cancer treatment and outcome. Substantial

advances in cancer treatments have resulted in significant decrease in mortality. However, existing cancer

therapies often result in high toxicity and nonspecific side effects. Therefore, better targeted delivery and

increased efficacy of drugs are crucial to overcome these effects. Osteopontin, a chemokine like protein plays

crucial role in regulating the oncogenic and angiogenic potential of various cancers including breast. Several

groups have demonstrated the role of Osteopontin in regulating the cell signaling that ultimately controls

tumor progression and metastasis covering all the hallmarks of cancer. During last several years, we have

demonstrated that both tumor and stroma-derived Osteopontin regulate tumor growth and angiogenesis

through induction of pro-angiogenic and metastasis associated genes. Recent data has shown that

circulating Osteopontin acts as predictive marker in development of hepatocellular carcinoma in a large

European population. It has been also reported that knocking down of Osteopontin in combination with PD-

L1 in macrophages suppresses lung adenocarcinoma cell migration. We have demonstrated that Osteopontin

signaling upregulates cyclooxygenase-2 expression in tumor-associated macrophages leading to enhanced

angiogenesis and melanoma growth via α9β1 integrin. Our earlier data showed that Osteopontin controls

HIF-1alpha dependent VEGF expression and breast tumor angiogenesis in response to hypoxia. Our recent

data revealed that Osteopontin transactivates normal fibroblasts to myofibroblasts and support breast tumor

progression in tumor microenvironment. Thus targeting Osteopontin and its regulated signaling network

could be novel therapeutic strategies for the management of breast and other cancers.

18


Guest of Honor– Inaugural Function

Prof. N. R. Sheth

Vice Chancellor,

Gujarat Technological University, Ahmedabad

BIODATA

Prof. (Dr.) Navin Sheth took over as the Vice-Chancellor of the Gujarat Technological University on December

31, 2016. A renowned educationist and administrator, Prof. Sheth started his academic career way back in

1979 and during the course of time, emerged as a tireless academician and herbal scientist. Born in Modasa

town of Aravalli district of Gujarat, Prof. Sheth had his early education in his hometown. He obtained his

B.Pharm. and M. Pharm degrees from L. M. College of Pharmacy, Gujarat University, Ahmedabad. He was

awarded the National Merit Scholarship for his graduation studies. He obtained Ph.D. degree from the

Saurashtra University, Rajkot. He started his academic career in 1979 as an Assistant lecturer at the B. K. Mody

Government Pharmacy College, Rajkot and was gradually promoted as the Lecturer, Reader and Principal

there. In 2007, he joined the Department of Pharmaceutical Sciences, Saurashtra University, Rajkot as the

Professor and Head. He has also served the Saurashtra University under various capacities like the Dean,

Faculty of Pharmacy, the Chairman, Board of Pharmaceutical Sciences, the Member of the Senate and the

Academic Council. A distinguished academician, staunch disciplinarian and an efficient administrator, Prof.

Sheth has also been the Member of the Peer Teams of the National Assessment and Accreditation Council -

NAAC and NBA. He has also served as the Member and Chairman of the various Committees of UGC/ AICTE

/DST/ GUJCOST and several Universities in India. He had been the Advisor and later on, Member of the GPSC.

In 2016, he took over as the Chairman of the Board of Pharmacy Education, AICTE. Prof. Sheth has attended

many national and international conferences in India and abroad. His research interests include Traditional

Drugs, Herbal Drugs and Standardization, Herbal formulations. His exuberant involvement in R&D has been

recognized by his 100+ publications including 65 technical papers in renowned research journals, 42 papers

in National Conferences 21 papers in the International Conferences. Till 2017, 20 research scholars had

successfully completed their doctoral research under his guidance. At present, 8 research scholars are

pursuing their Ph.D. under his supervision. About 21 of his former PG students are occupying key positions in

the various fields of Pharmacy. Prof. Sheth is awarded by Life Time Achievement Award at KLE University,

Karnataka during 20th National Conference of ISP at Belgaum, Karnataka, Indian Society of Pharmacognosy

2017 at Aurangabad and World Education Convention 2017 at New Delhi. Prof. Sheth has been associated

with various national and international associations and professional bodies as a member or a life member;

these include Indian Society of Technical Education, Indian Pharmaceutical Association, Indian Society for

Pharmacognosy, the Association of Pharmaceutical Teachers of India, All India Council Of Technical Education

(AICTE), Pharmacy Council Of India (PCI), Indian Institute of Management-Ahmedabad, Gujarat Forensic

Sciences University and B. V. Patel Pharmaceutical Education & Research Development (PERD) Centre. His

dream, vision, mission and efforts are directed towards making the Gujarat Technological University to a

world class University in the field of Science and Technology.

19

Chief Guest – Valedictory Function


Dr. Anamik Shah

Vice Chancellor, Gujarat Vidyapith, Ahmedabad

President, Indian Society of Chemists & Biologists

In charge, Centre of Excellence for Drug Discovery

Former Professor, Department of Chemistry, Saurashtra University, Rajkot

BIODATA

Prof. Anamik Shah is a Vice-Chancellor of Gujarat Vidyapith, Ahmedabad; founded by Mahatma Gandhi in

1920. Currently, he is looking after it’s various activities of education (Naitalim), higher education, constructive

social and extension programme at various level across Gujarat. He did his M.Sc (Chemistry) and Ph.D.

(Medicinal Chemistry) from Saurashtra University, Rajkot. He has 33 years of teaching and research

experience at Saurashtra University. He has published more than 205 papers in International and National

peer reviewed journals. His research area includes Synthetic Organic Chemistry, Analytical Environmental

Chemistry, Medicinal Chemistry, Natural products chemistry, Isolation & screening of marine based natural

products, QSAR, anticancer, anti-tubercular drug research, MDR reverter development and Analytical Method

Developments of Active Pharma Intermediates. He has worked as a Principal Investigator with No. Of Projects

related to Medicinal Chemistry, Anti-HIV, Anti-Cancer, MDR Revrters, Anti TB, Aromatase Inhibitors, Non

Nucleoside Reverse Transcriptase Inhibitors etc. funded by NIH (USA), DST, DBT, UGC, CSIR, DAE, MSME worth

Rs. 25 Crore. He has also completed several pharma related projects with industries like Alembic Limited,

AstraZeneca USA, Claris Life Sciences Ltd, Dabur Research Foundation and Primal Life Sciences. He has given

proven technology to Claris Life Sciences and Created National Facility for Drug Discovery Center, Centre of

Excellence (In drug delivery funded by Government of Gujarat, Government of India worth Rs.20crore in two

phases) at Saurashtra University, Rajkot, Gujarat, India. He has visited several countries like Singapore,

Malaysia, Taiwan, Netherlands, Germany, France, Italy, Switzerland, Greece, U.K., United States of

America/Mexico, Macao, China, Hong Kong for Scientific Purpose. He has supervised more than 60 PhD

Scholars and several M. Sc and M. Pharm (Ayurved) students for their Dissertation work.

He is also serving as Chairman - Gujarat Vidyapith Trust, President - Indian Society of Chemists and Biologists

(ISCB – Lucknow), Principal Investigator - Centre of Excellence (Saurashtra University, Rajkot), Trustee - Kaba

Gandhi no Delo (Rajkot), Trustee - Rashtriya Shala (Rajkot), Chairman - ‘Vishwamangalam

Trust’(Sabarkantha), Sardar Vallabhbhai Smarak Trust (Rajkot), Editor - ‘Vidyapith’ Research Journal, Board of

Director of ‘Anuvad Foundation’ (Non-profit organization), Chairman - Tribal Research and Training Institute

(TRTI - Gujarat Vidyapith) and Board of Directors, Vikram Sarabhai Science Centre.

20


Guest of Honor – Valedictory Function

Plenary Sessions

21

Role of Excipient Functionality in Drug Delivery

Prof. P. R. VaviaProfessor of Pharmaceutics & Dean, Academic Programme,

Institute of Chemical Technology, Mumbai

BIODATA

Prof. P. R. Vavia is a Professor in Pharmaceutics at The Institute of Chemical Technology, Mumbai. Currently, he

is the Dean of academic programmes at Institute of Chemical Technology. He has more than 29 years of

teaching experience to undergraduate, postgraduate and doctoral students. So far, Prof. Vavia has guided

over 55 Master students and 43 Ph.D. students who are placed at key positions in leading pharmaceutical

organizations. Presently, his research group comprises 5 masters and 15 Ph.D. students. Till date, he has 137

peer reviewed scientific publications in national and international journals to his credit, with more than 2745

citations and H-index of 27. Prof. Vavia has given more than 250 research presentations at national and

international levels. He has 8 granted patents, 38 complete patent specifications and 3 PCT applications filed

in the area of drug delivery.

ABSTRACT

Excipients are important part in formulation development that decide final dosage form as well as

pharmacokinetics and pharmacodynamics of drug being delivered. Over the past few years there has been

considerable interest in using polymers from various natural resources as a carrier in nanoparticle drug

delivery systems due to their multifaceted therapeutic benefits. These polymers with various functionality

can effectively deliver the drug into the target site which provides better therapeutic effect. Many plant

polysaccharides have been extensively investigated for their use in the development of novel carrier system

for drug delivery. Present talk is focusing on some of the important case studies where natural excipients are

successfully utilized in formulation development. Case studies focusing on successful delivery of natural

bioactives with novel drug delivery approach would also be discussed.

22


Non-Invasive Imaging Probes for Life Imaging

Dr. Anil K. MishraScientist "G",

Molecular Imaging and Research Centre

Institute of Nuclear Medicine and Allied Sciences, Delhi

BIODATA

Dr. A.K. Mishra is working as a Scientist at Institute of Nuclear Medicine and Allied Sciences, Defence

Research and Development Organization, Ministry of Defence, Govt. of India. He obtained his M.S.

(Chemistry) from Gorakhpur University, Gorakhpur, and Ph.D. (Chemistry) from Banaras Hindu University,

Varanasi. During his career, he held positions as Post-doctorate fellow at Universite de Bourgogne, Dijon,

France; Research Scientist at University of California, Davis, USA; Senior Scientist at INSERM U-463, Nantes,

France, and Visiting Professor at MaxPlanck Institute, Germany. Dr. Mishra has published more than 284

papers, in various journals of international repute. Dr Mishra is granted US, European and Indian patents. He

has received several awards and most prestigious one is DRDO-Young scientist by Prime Minister (Shri Atal

Bihari Vajpayee) of India in 1999. He is also serving as Honorary Professor at Deakin University [Australia],

Task force member [DBT and DST], Core Member of Radiopharmaceutical of India [DCGI], Associate Editor

[Frontiers in Nuclear Medicine] and Expert IAEA, Vienna. His Research Interest includes Molecular Imaging

Probes (SPECT-PET-MR-OI), Radiochemistry, Coordiantion chemistry, Synthetic chemistry and Bioconjugate

chemistry.

ABSTRACT

The tracing and extraction of biochemical of plant origin using non-invasive way is still in infancy stage.

However, all the biochemical of important nature to isolate and characterize required invasive or by

sacrificing the plants with laborious dissections by hand or to depend on less sensitive and non-specific

techniques. To overcome associated strenuous process, we have directed our efforts to develop smart and

specific agent to investigate in vivo topography, and connections and titration of biochemical's non-invasively

using imaging techniques. Our present study opens a new avenue to design and development of multimodal

molecular imaging probe of broad interest in development of affinity based probes. Imaging probes are a

special class of tracers that are used in conjunction with imaging techniques such as MRI, CT, and nuclear

imaging (PET and SPECT), allowing healthcare practitioners to see disease and injuries in a non-invasive way.

In the post genomics era, there is the opportunity to advance probes to the point where they can target

specific biochemical signatures associated with disease. Because changes in biochemistry occur before

diseases reach an advanced stage, molecular imaging probes will foster earlier and more personalized

diagnosis of disease. Our Lab is focused on bringing the power of modern synthesis to bear on the

development of molecular imaging probes and agents. These probes and agents are being developed to

visualize specific molecular targets and pathways in live cells, tissues and organism (from plants, mouse to

human). The specific aim is to 1) design and synthesize new imaging probes/agents, 2) develop and use

novel amplification schemes for the development of 'next generation' imaging probes, 3) optimize

pharmacokinetics and 'imagability', 4) efficiently synthesize and produce complex and diverse small

molecules, and test their ability as imaging agents. To design and synthesis the next generation of imaging

probes/agents for MRI, PET and SPECT, and optical imaging is the core mandate of our research lab.

23


Integrating Herbals into Modern Medicine

Prof. K. S. LaddhaProfessor of Pharmacognosy and Phytochemistry,

Institute of Chemical Technology, Mumbai

BIODATA

K. S. Laddha, Ph.D. (Tech.) is a Professor in Pharmacognosy and Phytochemistry at Dept. of Pharmaceutical

Sciences and Technology, Institute of Chemical Technology, Matunga, Mumbai. He has 29 years of Academic

experience and 4 years of industrial experience at different levels. His fields of specialization include

Extraction, isolation and characterization of phytoconstituents, Development of large scale extraction

technologies, Standardization of Ayurvedic/herbal drugs and formulations, Development of Ayurvedic/herbal

drug formulations, Chemical modification of phytoconstituents, Scientific studies on shodhan prakriya of

toxic plants in Ayurveda. He has published more than 100 papers, authored 7 books and 2 patents to his

credit. He has also published 58 monographs in 'Quality Standards of Indian Medicinal Plants' Volume 11

(2013), 12 (2014), 13 (2015), 14 (2016), 15 (2017), 16 (2018) published by Indian Council of Medical Research,

New Delhi. He has guided more than 20 Ph.D. scholars and 70 master's students. He has completed 23

sponsored projects including 8 from govt agencies such as MOFPI, DAE, AICTE, UGC, ICAR, AYUSH, ICMR,

RGSTC and 16 from industry such as Gufic Ltd, Mumbai; Colgate Palmolive, Mumbai; Kukadeshwar, Pune;

Sericare, Bangalore; Vedic Lifescience, Mumbai; Nandan Biotech, Hyderabad; Lesanto Labs., Mumbai; Geni

Herbs, USA; Genome Biotech, Mumbai; and Nisarga Biotech, Satara, 3 Total Herb Solutions P.Ltd. Mumbai;

Avenir Industries, Sharjah; Shanta Chemicals, Mumbai. Hindustan Lever, Mumbai. He has been a consultant

for many industries such as M/s. Aseel Herbals, Mumbai, M/s. Beniwal Agrobiotech, Bhivani, M/s. Pristine

Apiculture, ,Mumbai, M/s. Dhariwal Group, Pune, M/s. Charak Pharma P.Ltd., Mumbai, M/s. Total Herb

Solutions, Mumbai, M/s. Yucca Enterprises, Mumbai, Moleac Pte. Singapore, Tata International, Mumbai,

Pidilite Industries, Mumbai. Avenir Industries, Sharjah.

ABSTRACT

Herbals are now globally accepted as a valid healthcare system in the form of Phytopharmaceuticals,

functional foods, food supplements, etc., a trend recognized and advocated by the WHO. However,

development of rational phytomedicine requires great efforts in standardization of mono- and multi-

phytopreparations using all available high-tech methods; screening of extracts and their constituents by

integration of modern molecular biological bioassays; and controlled, clinical studies, inclusive of

pharmacokinetic and bioavailability investigations, aimed at evidence based phytotherapy. When botanical

medicine is fully developed then herbal products will be approved by FDA. Such approval would bring about

the establishment of required standards of quality for phytomdicine. Health practitioners will prescribe or

recommend both phytomedicine and synthetic medicine for various conditions, depending on which is

deemed more appropriate. Then the herbal medicine will have become integrated into conventional

medicine.

The talk will cover the aspects related to development of rational phytomedicine – opportunities, the path

ahead and challenges.

24


AYUSH and its Regulations and GCP

Dr. Kiran MarthakDirector - Management

Lambda Therapeutic Research Ltd., Ahmedabad

BIODATA

Dr. Kiran Marthak is a Member of the Board of Director in Lambda Therapeutic Research Ltd. He is also in

charge of Global Clinical development program of NCEs and Regulatory Affairs. He was also a founder

member and Board member of a CRO- Veeda CR. He has more than 35 years of experience in Clinical

Research including Pharmacovigilance. He had occupied Senior Management positions in MNCs like,

Novartis, German Remedies, Pfizer, Ranbaxy and GSK. He is a Vice Chairman of Medical Committee –IDMA,

Chairman of IEC- ISBEC and Member of Pharma Committee CII. He is actively involved in new initiatives in

DCGI office – Online submission of documents, New Rules for Clinical Trials and revising ICH-GCP Guidelines

etc. He has delivered Lectures in various International and National Conferences and Universities and

published numerous papers.

ABSTRACT

The Ministry of Ayurveda, Yoga and Naturopathy, Unani, Siddha and Homoeopathy, abbreviated as AYUSH, is

a governmental body in India purposed with developing, education and research in Indian traditional

medicine. It was created in March 1995 as the Department of Indian Systems of Medicine and Homoeopathy

(ISM&H). It is operated under the Ministry of Health and Family Welfare. AYUSH received its current name in

March 2003. The Ministry of AYUSH was formed with effect from 9 November 2014 by elevation of the

Department of AYUSH. There are more and more AYUSH products are being introduced in the market

compared to allopathic medicines. At the same time the Regulatory Authorities worldwide has become more

stringent for the approval of the products. The CDSCO Regulatory Guidelines will be discussed in brief along

with a touch on Phyto pharmaceuticals.

25


New Chemistries In The Quest For Novel Anti-

Inflammatory Scaffolds

Prof. A. K. ChakrabortiProfessor and Head, Department of Medicinal Chemistry, and Dean, National

Institute of Pharmaceutical Education and Research (NIPER), Mohali

BIODATA

Professor Asit K. Chakraborti obtained his M. Sc. degree in Organic Chemistry from the University of

Burdwan, West Bengal and Ph. D. degree in Synthetic Organic Chemistry from IACS, Kolkata. After post-

doctoral research training in USA in the department of Chemistry, Clemson University, South Carolina and in

Medicinal Chemistry at Purdue University, Indiana, USA, he joined the University of Burdwan as a faculty in

the department of Chemistry and served for the period 1990-1994. He joined the department of Medicinal

Chemistry, NIPER, S. A. S. Nagar, Punjab, India as Assistant Professor in 1994 and was elevated to the position

of Assoc. Professor in 1999 and to Professor and Head in 2001. Prof. Chakraborti has guided 38 Ph. D. and

130 Masters' students, published 173 research papers (with > 8900 citation with h index of 56), and filed 42

patents. He received several awards and recognition such as University Gold Medal, Bardhaman Sammilani

Gold Medal, ISMAS Eminent Mass-spectroscopist award, Ranbaxy Research Award (Pharmaceutical Sciences),

Chemical Research Society of India Bronze Medal and many more. His research interest is synthetic organic

and medicinal chemistry with thrust in new drug development in tuberculosis, leishmaniasis, and

inflammation to develop NMEs through development of novel synthetic methodologies (catalysis, C-H

activation etc.) in compliance with the green chemistry principles and deriving novel concepts (understanding

the molecular level role of acceleration of organic reactions in water and fluorous alcohols, the origin of the

organocatalytic potential of ionic liquids etc.).

ABSTRACT

Inflammation, though considered the normal defence mechanism of living systems, is the root cause of

several diseases if remains uncontrolled. The most common diseases caused due to inflammatory disorder

are COPD/asthma and arthritis. The enzymes PDE-IV and COX are the most popular targets for medicinal

chemists to generate new therapeutic agents to treat these diseases. While there are limited options to treat

COPD/asthma with roflumilast being the only candidate to received FDA approval as selective PDE-IV

inhibitor in the recent times the COXIBs (the selective inhibitors of COX-2) emerged as the most popular

drugs to treat arthritis. However, the drawbacks of the available therapeutics (nausea and vomiting in case of

roflumilast and the cardiac problems associated with the COXIBs that led to the withdrawal of several COXIBs

such as valdecoxib and rofecoxib) urge medicinal chemists to look for new structural scaffolds to generate

more effective agents to treat these diseases. Also at the same time, discovery medicinal research is

undergoing through a paradigm change that urges the need to enrich the medicinal chemists' tool box

fulfilling the green chemistry principles. However, despite of the small molecule drug discovery being driven

in synthetic organic chemistry expertise, the current trend in the medicinal chemistry the most frequently

used synthetic reactions are less represented by the innovative breakthroughs in chemistry. Such inclination

of discovery medicinal chemistry towards a handful of organic reactions lead to biased molecular architecture

with narrow scope of exploring the available chemical space. The present discussion will highlight the

integration of the innovative chemistries for C-H and C-X (X = Br/O) bond activation using novel concepts

such as co-operative catalysis by hetero-bimetallic nano clusters, to identify novel anti-inflammatory

scaffolds/agents.


26

Lab To Patent To Patient

Dr. Suresh PatankarChairman,

Department of Urology,

AMAI Trust's ACE Hospital and Research Center, Pune

BIODATA

Prof. Dr. Suresh Patankar is a well known urologist In this country. He has been into medical practice since

almost more than three decades now. He has the distinction of one qualified in both traditional as well as

modern systems of medicine and as such deftly combines the knowledge thereof for the good of his

patients. He is the founder chairman of AMAI Charitable Trust, Pune (Arogya Sewa Medical Academy of

India), which has under it , in the past three decades established Ace Hospital and Research Centre as a

reputed multi speciality healthcare centre engaged in providing quality tertiary care at affordable costs.

Prof. Dr. Patankar apart from being the chairperson of the dept. of urology at Ace hospital has been heading

the dept. of urology as a Professor at the B. J. Govt. Medical College and Sassoon General Hospitals , Pune

since 1998. He has been instrumental in establishing and developing the dept. of urology in Sassoon

General hospitals , Pune . He is a pioneer of several urological surgical procedures in Pune and India. He has

been selflessly rendering services to the esteemed institution on a nominal remuneration .

He has been actively engaged in the development of innovative technological devices for minimal access

surgery. His researching mind has been constantly working to reduce the cost of the present state of the art

equipment by promoting better, economical and indigenous solutions.

His research work is path breaking and probably the first of its kind in traditional medicines. His research

medicines have shown successful results in more than 3000 patients. In today’s world of rising medical costs

these medicines are economical to the common man.

He has been honored with the highest national award in Urology ‘ The Pinnamenani Venkateswara Rao

Oration’, Citation and Gold medal in 2015 for his outstanding contributions.

He is one of the few individuals who has painstakingly conducted clinical research trials for scientifically

validating traditional formulations for kidney stones, wound healing and other urological disorders for which

there are no convincing solutions in the modern system. He is the first urologist to be awarded a research

grant by DSIR, GOI, under TePP for his research on a herbal formulation .

He has obtained two US , two European and one Indian patent till date. Patent search has found that he is

the only Indian national natural to obtain two or more patents on herbal formulations (and also on kidney

disorders) in the territories of US, Europe and India. He has been a member of the Senate, the Super

speciality Board of Studies, the Research Advisory Board and the Board of Yoga & Naturopathy with

Maharashtra University of Health Sciences. He is also the Governor’s (Chancellor) nominee to the

management council of Maharashtra University of Health Sciences.

27


He has presented his work on several national and international platforms. He has to his credit two books on

research methodology that emphasize scientific validation of traditional medicines. He has numerous

publications to his name in indexed journals of urology, integrative and alternative medicine, both national

and international. The research work carried out by him has been cited in international textbook of urology.

He has successfully organized many international workshops in India that hugely impacted the training of

aspiring surgeons that would ultimately benefit the society.

Considering his extensive experience, dedication and research contributions to traditional medicine the Govt.

of India (Ministry of AYUSH) has appointed him as an expert member on Central Council of Indian Medicine.

ABSTRACT

Research in Indian Subcontinent is lacking in all fields including medical and para medical sciences. In fact,

one of the reasons for the development/progress in western countries is constant pursuit of research and

innovation, and it is because of this western world is in for front on all aspects of human life including quality

of life of citizen of these countries. USA is glorying example for this; which is the melting pot of all research

and innovation in the world.

Whatever research is done our country is rarely of Global standard. Not only that, any research should be

useful to the society at the end and should not remain in lab level. Fortunately, this is not the scenario today

in our country. Government also has recognized this and new movement has started as “Make in India”. As

professional all of us must contribute to this concept.

Today I will talk about ‘Lab to Patent to Patient’ Any research starts in the lab, which has to be validated, the

concept has to be patented; which proves that that it is a novel innovation and ultimately this research should

help the patients and the society.

I will be talking about ‘Research in Urology’ (i.e. Kidney Disorders) with Indian perspective. Its about alternate

therapies, which is ‘Treasure of Knowledge’ of our culture which has been validated on Global platform and

received US/ European patents, accepted in modern medical community including US and used with

successful reports in large patient population.

28


Nanopharmaceuticals: Challenges And Opportunities

For Phytotherapeutics

Prof. Javed AliProfessor (Pharmaceutics),

School of Pharmaceutical Education and Research

(Formerly Faculty of Pharmacy), Jamia Hamdard, New Delhi

BIODATA

Prof. Javed Ali passed his B. Pharm. and M. Pharm. with distinction from the Faculty of Pharmacy, Jamia

Hamdard and bagged gold medals in 1994 and 1996 respectively. He earned a Ph. D. in the year 2000. He

was a post-doctoral fellow at the Institute of Pharmaceutical Technology, University of Frankfurt, Germany in

2005. He has a total experience of 22 years in teaching and research. Presently he is working as Professor at

Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi.

Prof. Ali has been bestowed with several honours, a few of them worth mentioning include, the Career award

for young Teachers by AICTE (2003), APTI-Young Pharmacy Teacher of the year (2004), by Association of

Pharmacy Teachers of India, the BOYSCAST Fellowship of Department of Science and Technology, Govt. of

India (2005), Prof. M.L. Khorana Memorial Prize for the year 2006 for the best paper in the field of

Pharmaceutics & Bio-pharmaceutics, American Association of Indian Pharmaceutical Scientists (AAIPS) –IPA

Distinguished Educator and Researcher Award 2007 at the Association meeting at San Diego, USA. Research

Award 2014 by UGC, INSA Teachers Award 2018 for his outstanding teaching methodology and research

outputs.

Prof. Ali has received research grants from UGC/ ICMR/ AYUSH/AICTE/DRDO/DST/FIP (The Netherlands/ICMR

industries etc. He is also consultant to industries. His research interests include Improving oral bioavailability

of BCS class II and Class IV drugs using polymeric conjugates and lipid based systems like microemulsions,

nanoemulsions, solid lipid nanoparticles and nanostructured lipid carriers. He is also working on

nanoparticulate systems for herbal drug moieties for the treatment of acne and psoriasis. He is actively

involved in formulating nanoparticulate drug delivery systems for brain delivery for treatment of CNS

disorders. He is supervising scientific research of the post-graduation and the doctoral level. He has

guided/under guidance about 67 theses of M. Pharm. and 41 theses of Ph. D. He has written several

textbooks and has contributed several chapters in books on Controlled and Novel Drug Delivery Systems of

Indian and International Publisher. A widely traveled person, he has presented his research work in about 50

conferences held in India and abroad. He has a list of more than 290 manuscripts in journals of repute and

five Indian Patent granted/applied. He has H- index of 49, i10 of 159 and more than 10782 citations to his

credit as per Google Scholar on 03 Jan., 2019. He is also in-charge of IP Management cell of Jamia Hamdard.

He has also worked as paper coordinator of UGC e-pathshala project for two papers of Pharmaceutical

Sciences. He is reviewer to a large number of international and national Journals of repute. He is in the

editorial board of many journals.

Prof. Ali is also actively engaged in various committees of the department, faculty and University and

Government of India. He is involved as executive member IPA (Delhi Branch) 2012- till date. He had been

29


member of local organizing Scientific Committees of conferences. He had delivered talks at University of

Frankfurt, University of Düsseldorf (Germany), and University of Findlay, USA. He is a resource person and has

organized staff development/refresher/short term training programmes. He is a member/Life member of 20

Indian and international scientific organizations.

ABSTRACT

Herbal medicines have been widely used all over the world since ancient times and have been recognized by

physicians and patients for their better therapeutic value as they have fewer adverse effects as compared with

modern medicines. Though they present many advantages over modern medicine, lack of scientific approach,

inadequate standardization and patient compliance limit them from being used extensively but the recent

technological advancement in nanotechnology has unlocked new avenues for research and development in

the field of phyto-medicine. Phytotherapeutics now has a scientific approach in delivering the components in

a sustained manner to increase patient compliance and avoid repeated administration which has been

achieved by designing novel drug delivery systems (NDDSs) for herbal constituents. NDDSs not only reduce

the repeated administration to overcome non-compliance but also help to increase the therapeutic value by

reducing toxicity and increasing the bioavailability. Polymeric nanoparticles/nanocapsules, liposomes, pro-

liposomes, solid lipid nanoparticles, nanoemulsions/microemulsions, etc. are few examples of

nanopharmaceuticals (NPhs) that have been successfully developed or are under research for efficient

delivery of herbal actives and extracts. The presentation will cover the different aspects of applications of

NPhs for herbal actives and extracts. Prototype examples of various Nanopharmaceuticals will be also

discussed.

30


Drug Discovery from Natural Sources- Challenges and

Case studies

Prof. Krishnapriya MohanrajVice Principal (Administration and Strategy)

Professor, Department of Pharmaceutical Analysis

Bombay College of Pharmacy, Mumbai

BIODATA

Prof. Krishnapriya Mohanraj is an excellent educator, motivating and training students, analysts, chemists and

faculty in the nuances of pharmaceutical analysis and medicinal chemistry; and a researcher developing novel

and cost-effective techniques useful for the industry. She did her B Pharm from C U Shah College of

Pharmacy, SNDT Women’s University, Mumbai and M. Pharm and PhD (Tech) in Pharmaceutical Chemistry

from Institute of Chemical Technology (formerly UDCT), Mumbai. Professor Krishnapriya was selected for the

UKIERI Indo UK Staff Exchange Program at Kingston University by the British Council (2011-12 award). She

has been resource person at various seminars, faculty development programs and technical conferences for

the pharmaceutical industry, including the 4th IPA-EDQM Technical conference, Mumbai organized by the

Indian Pharmaceutical Association and European Directorate for Quality Medicines and Healthcare and

Chiral India 2012 and 2015. She has one patent and has coauthored a book – ‘Synthesis of Drugs- a Synthon

Approach’. She has 17 presentations and 26 publications to her credit, four of which have won awards. Her

expertise includes Chiral chromatography, Computer aided drug design, synthesis and pharmacological

evaluation, Enzymatic resolution, Bioassay guided fractionation of herbal extracts, Bioanalysis, In vitro

analysis, LC-MS/MS studies, Structural Elucidation, Impurity profiling and development of stability indicating

methods. She has received research funding of more than 7 crores from various agencies like Department of

Science and Technology, Department of Biotechnology, AYUSH, All India Council of Technical Education,

University Grants Commission, University of Mumbai, Amrut Mody Research Fund and industries like Aventis

Pharma, Glaxo Smith Kline, Sandu Pharmaceuticals Ltd, Shogun Organics, Ambernath Organics, Aarti Health

Care, S G Pharma, Nature Pure Extracts and Analytical Solutions. She has also done 14 collaborative projects

with many industries like Marico, Cipla, USV, Torrent and Piramal Life Sciences Ltd. Recently, she along with Dr

Vaishali Shirsat, received sanction of Rs 5.87 crores for establishment of National Facility of Research and

Training in Integrated Analytical Strategies for Discovery, Development and Testing of Drugs, Pharmaceuticals

and Nutraceuticals at Bombay College of Pharmacy under the Drugs and Pharmaceuticals Research

Promotion Scheme of the Department of Science and Technology. Instruments procured include LC-MSMS,

ICP-MS and HPTLC-MS.

ABSTRACT

Lead identification is one of the most crucial steps in the drug discovery process. Natural products, with their

plethora of constituents are a rich source of lead compounds. Challenges encountered during Drug Discovery

from Natural Sources include authentication and identification, seasonal and regional variations, problems

during invitro pharmacological evaluation, isolation of bioactive constituents and their characterization.

Bioactivity guided fractionation of Neem leaf extract and Nutmeg for lead identification for antiplatelet

activity and anti- fungal activity respectively, will be discussed in the case studies.

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ADME Studies for Rational Integration of Natural

Products and Modern Medicine

Dr. Jyoti PaliwalDirector,

PHAEX Consulting, Gurugram

BIODATA

Jyoti Paliwal had been serving Indian Pharmaceutical institutions, industry and academia for more than three

decades. He has worked in a variety of administrative, academic, research and clinical trial capacities, stating

his career with UP drugs and Pharmaceuticals followed by Central drug research Institute, (CDRI), University

of Michigan, Ranbaxy, Wockhardt, BV Patel Pharmaceutical Education & Research Centre (PERD), National

Institute of Pharmaceutical Education and Research (NIPER)-Mohali, Troikaa Pharmaceuticals. At present, he is

working as a free- lancing consultant to Industry, Academia and Regulatory agencies. He has acquired in

depth experience working in multidisciplinary teams involved in target selection, lead optimization and the

pre-clinical and clinical development of New Chemical Entities. During his tenure at Ranbaxy, Prof. Paliwal was

a key member of joint research teams with Schwarz Pharma Germany, MMV Switzerland and GSK USA for

their collaborative projects. He has developed, trained and led teams in clinical research, pharmacokinetics,

metabolism and bioanalytics and set up several laboratories. Dr. Paliwal possesses a Ph D (Central Drug

Research Institute) an M Pharm (Pharmaceutics) from Nagpur University, and Diploma in Business

Management (Nagpur, India). He has been associated with academics in India & abroad as visiting faculty,

examiner and guide for Ph D programs. Prof. Paliwal has authored over 55 research articles and reviews in

peer-reviewed journals, has delivered over 100 talks at national and international symposia.

ABSTRACT

Large number of people and health care providers are using Natural products (NP) along with modern

medicine for a variety of diseases and health issues. In spite of their widespread use, either alone or along

with modern medicine, robust scientific evidence on their safety, efficacy and dosage regime is missing.

Further, the chemical diversity of NP surpasses all man made synthetic libraries of small molecules and

continue to inspire novel discoveries in chemistry, biology, and medicine. However, most of the

pharmaceutical companies have significantly scaled down or abandoned their NP programs and not much is

being done to explore their ADME profiles. It is estimated that approximately half of all new drug approvals

can trace back to a natural product scaffold origin. Establishing the pharmacological basis for efficacy and

dosage regimens of NP is a constant challenge. Of particular interest is the question of bioavailability to

assess to what degree and how fast compounds are absorbed after administration of NPs. Of further interest

is the elucidation of metabolic pathways (yielding potentially new active compounds), and the assessment of

elimination routes and their kinetics. These data become an important issue to link data from

pharmacological assays and clinical effects. Of interest are currently also interactions of NPs with synthetically

derived drug products. A better understanding of the ADME properties, bioavailability interaction potential of

NPs can help in designing rational combinations and dosage regimens. In this presentation ADME studies of

widely used NPs will be discussed. Furthermore, various drug interactions are discussed which show that

caution should be exercised while integrating NP with modern Medicine.

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Panel Discussion

33

Panel Discussion

Topic: Integrating natural and modern medicines in drug development life cycle for better health

outcomes: Need or Mandate?

Moderator

Dr. Suresh Patankar

Panelist

Prof. Krishnapriya Mohanraj

Mr. S. B. Dangayach

Dr. Jyoti Paliwal

Dr. Rakesh Rawal

Dr. Sarat Dalai

Dr. Shivprakash Rathnam

Mr. Satyanarayan Banwarilal Dangayach

Mr. S.B. Dangayach is distinguished alumnus of IIM Ahmedabad with India centric mind set focused on social,

economic and technological spheres. Mr. Dangayach is a passionate proponent of green, clean and

sustainable development and has hence devoted all his efforts to evolve products and solutions in domains

of water, wastewater, affordable housing, social infrastructure, renewable energy, waste management and

health. With proven record of innovation and entrepreneurship he has the ability to ideate, strategize and

implement projects, programmes and plans by proper interdisciplinary coordination and leadership. Mr.

Dangayach has helped in building brand “Sintex” into a formidable entity offering innovative and affordable

solution across sectors during his long career of over 42 years in leadership position including over a decade

as Managing Director. He is currently associated with Sintex group of Companies as Director and is Chairman

of Healwell International Limited. Mr. Dangayach received “Best Manager” award of 1998 from Ahmedabad

Management Association. He is also featured in bestselling book “Stay Hungry Stay Foolish” of Rashmi

Bansal as a role model for entrepreneurs.

Mr. Dangayach has been part of many foreign delegations of Prime Minister and Chief Minister of Gujarat.

Some of the noteworthy milestones are:

• Regular speaker at many symposia, seminars and conferences relating to plastics, environment,

affordable housing, Homoeopathy, renewable energy, waste management, water etc.

• Conceptualized and anchored popular series of lectures at Ahmedabad Management Association under

title of “New Paradigm in Health – Illness to Wellness and Beyond”.

• Ex-Chairman of National Advisory Board of Plastindia Foundation.

• Member of Advisory Committee on Vibrant Gujarat since beginning.

• Visualized and created Sintex Chair at CEPT University for sustainable building materials and

technologies.

• Created and delivered a course on “Waste Business Management” at IIM, Ahmedabad to highlight

immense business opportunities in the domain of waste.

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• Created and delivered a course on “Doing Business with Government & PSU’s” at Entrepreneurship

Development Institute, Gandhinagar.

• Independent Director on Board of Gujarat Mineral Development Corporation Limited and Gujarat

Industrial Power Company Limited.

Dr. Rakesh Rawal

Dr. Rakesh Rawal is Professor in Life-Science, Gujarat University with 26 years of experience at Gujarat Cancer

Research Institute (GCRI), Ahmedabad. He received PhD in “Role of Biochemical markers in Oral cancer” at

GCRI under Gujarat University in 1999. His last designation at GCRI was Senior scientific officer & Head,

Divison of Medicinal Chemistry & Pharmacogenomics where he did a lot of work on cancer stem cells,

biological screening assays for new synthetic/natural anticancer agents. He has more than 60 research

publications of national and International repute to his credit. He is in the academic & advisory board of

many prestigious institution e.g. GSBTM, NIF, NIRMA. He is in the board of directors of GUSEC (Gujarat

University Startup & Enterpreneurship Council) and co-ordinator for Virtual Lab with IIT-Mumbai. He has 15

research projects from various agencies. His area of interest include Establishing a tumour repository for

Biomarker development using Genomic and Proteomic technologies, Insilico analysis of Drug target and

Invitro models for Cancer stem cell to predict drug response and resistance. He is also interested in

Regenerative Medicine using cell based therapy in cancer management.

Dr. Sarat Dalai

Graduated from Utkal University with B.Sc. in Physics (Hons) in 1990, he did M.Sc. (Biotechnology) from JNU

in 1992 followed by Ph.D. (Immunology) from JNU in 1998. Went to USA for post-Ph.D. research at NIH, Johns

Hopkins Medical School and worked as a scientist for US military Malaria Vaccine Development program at

Walter Reed Army Research Institute before return to India in 2011. Passionate Researcher and Teacher

having strong belief in changing the society through scientific endeavor by motivating younger generation of

students.

Current Research Interest: The laboratory at the Institute of science is working on generation and

maintenance of memory T cells vis-a-vis vaccine development. The major focus of the research is to

understand the CD 8T cell responses to plasmodia liver stage infection. The laboratory is also working on

developing alternative strategy for making effective vaccines that could provide long term protection.

Further, the efforts of lab is also to develop chimeric biomolecules for novel adjuvant and to treat cancer

through immunotherapy.

Dr. Shivprakash Rathnam

Dr. Shivprakash Rathnam is PhD from LM College of Pharmacy, Ahmedabad. Dr. Rathnam was Head-

Pharmacology Research, Zydus Cadila Healthcare up to 1996. He served Sun Pharma Advanced Research

Centre (SPARC), Baroda as Head-Pre-Clinical Pharmacology and Toxicology and later started his own

company Synchron Research Services Pvt. Ltd. a CRO in 1998. Synchron is the first CRO in India in Private

Sector totally dedicated to BA/BE studies and Clinical Research. At present he is the Founder & Managing

Director of Synchron Research. He started Synchron in Thailand in 2007 and acquired 100% PAREXEL Bio-

analytical facility in France in 2007. He also started Avance Phytotherapies in 2003 to formulate effective

therapies for those ailments for which there is no allopathic intervention and started INTERVEIN, a central lab

for clinical trials in 2006. He is the Founder Chairman of the company. He is the former Chief Editor of Indian

Journal of Pharmacology (2007-2009). He has more than 60 research papers published in various

International and national journals. He has written many articles in various magazines and book chapters. He

has co-authored a book on Screening Methods in Pharmacology with Late Prof. NS Parmar. Dr. Shivprakash

was awarded " Udyog Ratttan Award" by Institute of Economic Studies in 2008 for his contribution for the

development of Clinical Research in India.

35


Acknowledgements


36

Sponsors

• Daxal Cosmetics Pvt. Ltd., Ahmedabad

• Mehta Sales Corporation, Ahmedabad

• Tarushi Formulations LLP, Ruppur

• Avancé Phytotherapies Pvt. Ltd., Ahmedabad

• Scientific Trading Corporation, Ahmedabad

• Manisha Enterprise, Ahmedabad

• Surekh Educational, Ahmedabad

• Progenbiolab Technologies, Delhi

• Keval Sales Corporations

• Paras Solutions, Mehsana

• Shyam Medico, Ahmedabad

• Prexa Scientific, Ahmedabad

• Yash Enterprise, Ahmedabad

• Genei Laboratories Pvt. Ltd., Bengaluru

Media Partners

Address for correspondence:

The Organizing Secretary – NCIP - 2019

Institute of Pharmacy, Nirma University, S. G. Highway,

Ahmedabad - 382481, Gujarat, INDIA

Phone: +91-30642721 • Fax: +91-2717-241916

Website : http://www.ncip.in

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