Natural or Man-made Chemicals?
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Natural or Man-made Chemicals? Adapted from a presentation by Penny Le Couteur, The Fraser Institute, Vancouver, Canada
description
Natural or Man-made Chemicals?. Adapted from a presentation by Penny Le Couteur, The Fraser Institute, Vancouver, Canada. “All substances are poisonous,. there is none which is not a poison; the right dose differentiates a poison from a remedy.” . Paracelsus circa 1538. The great myth. - PowerPoint PPT Presentation
Transcript of Natural or Man-made Chemicals?
Natural or Man-made Chemicals?
Adapted from a presentation by Penny Le Couteur,
The Fraser Institute, Vancouver, Canada
“All substances are poisonous,there is none which is not a poison; the right dose differentiates a poison from a remedy.”
Paracelsus circa 1538
The great myth
“Natural is good; man-made is bad”
It may be natural but you’ll be just as dead!
The seven most deadly chemical compounds
LD50 /mg/kg
Botulinum toxin A 3 x 10-8
Tetanus toxin A 5 x 10-6
Diphtheria toxin 3 x 10-4
Dioxin * 3 x 10-2
Muscarine 2 x 10-1
Bufotoxin 4 x 10-1
Sarin * 4 x 10-1
LD50 = The lethal dose of a compound for 50% of animals exposed
* Synthetic
Viktor YushchenkoPresident of the Ukraine
July 2004 December 2004
Muscarine - from mushrooms
OCH2
H3C
HO
N
CH3
CH3
CH3
Cl
Bufotoxin – from the common toad
O
CH3
OH
O
CH3
O C
O
CH3
O
C
(CH2)6O C
O
NH CH
COOH
CH2 CH2 CH2 NH C
NH
NH2
