National Cancer Control Programmes - Planning, Implementation, Monitoring and Evaluation

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    National Cancer Control Programmes

    Planning, implementation, monitoring and

    evaluation

    Dr D. Maxwell Parkin

    University of Oxford, UK

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    Priorities in cancer control

    1. Prevention

    2. Early detection3. Treatment

    4. Palliative care

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    A public health programme designed to reducethe incidence and mortality of cancer and

    improve the quality of life of cancer patients

    CANCER CONTROL PROGRAMME

    It works through the systematic and equitableimplementation ofevidence-based strategiesfor prevention, earlydetection, diagnosis, treatment, and palliation

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    5 steps of cancer control planning

    Assess needs and capacity

    Decide approach to planning Develop the plan

    Implementation

    Evaluation

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    Measuring

    Burden of cancer

    Past trendsFuture projections

    identifying the health problems,

    determining priorities for preventive and curative programmes

    NEEDS ANALYSIS: where are we now?

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    INDONESIA: Cancer cases, 2002

    25%

    15%

    9%8%6%5%

    4%

    3%

    3%2%

    Breast

    Cervix uteri

    Colon and rectum

    Ovary etc.

    Lung

    Corpus uteri

    Thyroid

    Non-Hodgkin lymphoma

    Leukaemia

    Liver

    19%

    12%

    11%

    6%7%

    6%

    5%

    4%

    3%

    2%

    Lung

    Colon and rectum

    Liver

    Prostate

    Non-Hodgkin lymphoma

    Nasopharynx

    Leukaemia

    Bladder

    Stomach

    Oral cavity & pharynx(excl NPC)

    Males 80,000

    Females 102,000

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    Trends in Colon Cancer Incidence: ASIAAge Standardised Rate (World), MALES

    SingaporeChinese

    Hong Kong

    Osaka

    Manila

    Bombay

    .

    .

    ..

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    PLANNING NCCPsI DEFINING THE MAGNITUDE OF THE PROBLEMBurden of cancerPast trendsFuture projections

    II REVIEW PROFILE OF RISK FACTORS

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    Major causes of cancer: World 2001 (GBD 2006)

    0 10 20 30

    Pollution

    Physical inactivity

    Overweight

    Alcohol

    Diet

    Infection

    Tobacco

    Percent of all cancer

    Bar 1

    H. pylori

    HPV

    Hepatitis viruses

    Low fruit & veg.

    Bar 6

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    PLANNING NCCPsI DEFINING THE MAGNITUDE OF THE PROBLEMBurden of cancerPast trendsFuture projections

    II REVIEW PROFILE OF RISK FACTORS

    III ASSESSMENT OF CAPACITYIV SETTING PRIORITIES FOR INTERVENTION

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    NCCP : intervention stategies

    Prevention

    Early detection

    Diagnosis and Treatment

    Palliative care

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    Activities of a Cancer Control Programme

    For each:

    Identify the immediate target

    Estimate the impact (quantify reduction in

    incidence and mortality)

    Estimate the resources needed

    Estimate the cost of the activity

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    (PRIMARY) PREVENTION

    Occupation

    ..

    Tobacco

    Infection

    Diet/Obesity/Physical exercise

    Reproductive factors

    AvoidanceImmunisationTreatment

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    Male FemaleEastern Africa 0.0 0.0Middle Africa 1.7 0.0Northern Africa 14.8 0.0

    Southern Africa 18.7 3.4Western Africa 0.0 0.0Carribean 22.4 6.3Central America 14.8 3.4Temperate S. America 25.6 3.2Tropical S. America 17.1 4.0Northern America 24.5 16.5

    China 7.0 4.6Japan 28.0 10.6Other East Asia 35.4 10.8South-Eastern Asia 27.8 7.4South-Central Asia 13.5 0.0Western Asia 27.9 0.2Eastern Europe 42.3 4.1Northern Europe 25.4 11.4

    Southern Europe 36.5 3.0Western Europe 29.4 4.4Australia/New Zealand 17.9 8.6Melanesia 0.7 0.0Micronesia/Polynesia 29.7 11.1

    WORLD 27.9 5.9

    Developed countries 30.8 9.1Developing countries 25.2 3.1

    Percentages of all cancer cases attributable to tobacco smoking

    INDONESIA: Tobacco Use in 2005 (WHO InfoBase)

    daily cigarette use 53.6% males, 2.8% females

    daily smoking tobacco 58.4% males 3.2% females

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    INTERVENTIONS TO REDUCE DEMAND FOR TOBACCO

    TOBACCO TAXATION

    RESTRICTIONS ON SMOKING

    BANS ON ADVERTISING AND PROMOTING

    HEALTH INFORMATION AND COUNTER-ADVERTISING

    SMOKING CESSATION TREATMENTS

    INTERVENTIONS TO REDUCE SUPPLY OF TOBACCO

    FRAMEWORK CONVENTION ON TOBACCO CONTROL

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    LIVER CANCER & Hepatitis virusesIndonesia

    HBsAg positive ~9%

    Anti-HCV positive ~2%

    HBV(45%)

    HCV

    (10%)

    Both(18%)

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    INDONESIA: Prevalence of overweight and obesity (2005)

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    CANCER CONTROL

    Prevention

    Screening & Early Detection

    Treatment

    Rehabilitation / Palliation

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    Early detection

    Screening: organised efforts to detect early disease in

    asymptomatic populations by mass application of simpletests at regular intervals.

    Early clinical diagnosis: detection of early clinical

    stages of disease in symptomatic subjects.

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    Screening programmes should be undertaken only when

    their cost effectiveness has been demonstrated, sufficient resources are available to adequately cover the target group

    with screening tests, to investigate those with positive tests, and toprovide treatment and follow-up care,

    the incidence of disease is high enough to justify the efforts and costsof screening

    0 5 10 15 20 25 30 35

    Australia

    Norway

    Indonesia

    World

    Korea, Republic

    Poland

    Less developed countries

    Thailand

    Philippines

    Bangladesh

    India

    Cancer of

    cervix

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    Methods of screening for breast cancer

    1. Imaging: mammography

    2. Physical examination

    3. Self-examination

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    INDONESIAa mammography screening programme?

    17 million women aged 45-64.

    Screening every two years would require some 6-7 million tests every year

    Of these, some 3-8% (say 300,000) would require follow up investigation for an

    abnormal mammogram.

    Each year, there are some 7-8000 deaths from breast cancer at ages 45-

    64, and 2500 over the age of 45.

    A screening programme is expected to reduce mortality by ~ 20%

    The maximum saving from this huge input of resources would therefore

    be 2000 deaths

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    Early clinical diagnosis:

    The detection of early clinical stages of disease insymptomatic or high-risk subjects. requires:

    Increasing awareness of the population of earlywarning signs of the disease

    orienting health personnel towards early diagnosis ofcommon forms of curable cancers

    empowering them to seek early clinical attention.

    ALTERNATIVE:

    MANILA PHILIPPINES

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    MANILA, PHILIPPINES

    Breast cancer by stage at diagnosis1995

    II 50%III 23%

    IV 8%

    Unk 13%

    In situ1% I 4%

    Stage II+:94%

    P f i d l f h l (NPC) b d

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    Devi, B. et al. Ann Oncol 2007 18:1172-1176; doi:10.1093/annonc/mdm105

    Percentage of patients presented at late stage for nasopharyngeal cancer (NPC), breast andcervix in Department of Radiotherapy and Oncology (DRO), Sarawak General Hospital (SGH)

    (1991-1999) , following a programme of training of health personnel to improve their skills in early

    detection of these cancers (1991-1996), and, at the same time, a public education programme to raise

    awareness of these diseases, and their early signs and symptoms

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    Priorities in cancer control

    1. Prevention

    2. Early detection3. Treatment

    Cancer therapy often relatively expensive

    - making the best use of available resources

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    Two recommendations from the Institute of Medicine committee on

    cancer control in low and medium income countries, 2006

    Countries should consider establishing a government-supported cancer

    center of excellence that provides resource-level appropriate services to

    the public and acts as a reference point for national cancer control.

    Resource-level specific guidelines for the overall management of major

    cancers for which treatment can make a substantial difference in a

    meaningful proportion of patients should be developed

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    Palliative Care

    Management of pain

    (and otherproblems, physical, psychosocia

    l and spiritual)

    Concerned with QUALITY OF LIFE

    Prevent & relieve sufferingthrough:

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    Surveillance is an essential component of a NCCP

    Setting priorities

    Setting objectives

    Evaluating outcome

    Comparing with resource inputs

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    EVALUATION OF

    Effectiveness

    Does the programme achieve its objective?

    Efficiency

    Costs in relation to outcome

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    Thank you