Nasense Labs Private Limitednasense.com/Nasense pdfs/corporatebrochure.pdf · Our core products are...

12
Email: [email protected] Manufacturing Facility Plot Numbers 24 & 25 SV Cooperative Industrial Estate Jeedimetla, Quthubullapur (M) Hyderabad 500 055 Andhra Pradesh, India +91 40 64643570 / 71 Nasense Labs Private Limited Tools for Organic Synthesis Phase Transfer Catalysts Fine Chemicals Pharmaceutical Ingredients Corporate Office Plot Number D-70 Madhuranagar (Behind Vellanki Foods) Hyderabad 500 038 Andhra Pradesh, India +91 40 64643572 / 73 / 74 Website: www.nasense.com Fax: +91 40 23713572 We are Nasense Labs, an established manufacturer of Fine Chemicals and Pharmaceutical Ingredients. Our company was originally incorporated as USP Organics Private Limited, in the year 2002. After an extensive rebranding project, it was renamed as Nasense Labs Private Limited, effective from June 26, 2012. Our core products are a set of high-precision tools for organic syntheses, used in a variety of chemical processes across multiple industry sectors. We specialize in 100% conversion reactions, and are dedicated to the development of clean, flexible and quality-specific production systems. We are highly competent in the manufacture of Sodium based products, and have recently developed systems for a number of Iodine and Selenium based products. We also specialize in the manufacture of Pyridine Derivatives and Phase Transfer Catalysts, and have the capability to work on a wide range of molecules in these categories. Although we are a recent entrant in the pharmaceutical industry, our engineering and process design competences enable us to produce high quality pharmaceutical ingredients in a maximally efficient, reduced effluent-load system.

Transcript of Nasense Labs Private Limitednasense.com/Nasense pdfs/corporatebrochure.pdf · Our core products are...

Email: [email protected]

Manufacturing Facility Plot Numbers 24 & 25 SV Cooperative Industrial Estate Jeedimetla, Quthubullapur (M)

Hyderabad – 500 055 Andhra Pradesh, India +91 40 64643570 / 71

Nasense Labs Private Limited

Tools for Organic Synthesis – Phase Transfer Catalysts – Fine Chemicals – Pharmaceutical Ingredients

Corporate Office Plot Number D-70

Madhuranagar (Behind Vellanki Foods)

Hyderabad – 500 038 Andhra Pradesh, India

+91 40 64643572 / 73 / 74

Website: www.nasense.com

Fax: +91 40 23713572

We are Nasense Labs, an established manufacturer of Fine Chemicals and Pharmaceutical Ingredients.

Our company was originally incorporated as USP Organics Private Limited, in the year 2002. After

an extensive rebranding project, it was renamed as Nasense Labs Private Limited, effective from

June 26, 2012.

Our core products are a set of high-precision tools for organic syntheses, used in a variety of

chemical processes across multiple industry sectors. We specialize in 100% conversion reactions,

and are dedicated to the development of clean, flexible and quality-specific production systems.

We are highly competent in the manufacture of Sodium based products, and have recently

developed systems for a number of Iodine and Selenium based products. We also specialize in the

manufacture of Pyridine Derivatives and Phase Transfer Catalysts, and have the capability to work

on a wide range of molecules in these categories.

Although we are a recent entrant in the pharmaceutical industry, our engineering and process

design competences enable us to produce high quality pharmaceutical ingredients in a maximally

efficient, reduced effluent-load system.

Tools for Organic Synthesis – Phase Transfer Catalysts – Fine Chemicals – Pharmaceutical Ingredients

Nasense Labs Private Limited

Product List (1)

Category Product CAS Number Status

Tools for Organic Synthesis

Sodium Hydride (60% in LLP Oil) 7646-69-7 Commercial - Regular

Sodium Amide 7782-92-5 Commercial - Regular

Sodium Tertiary Butoxide 865-48-5 Commercial - Regular

Magnesium Tertiary Butoxide 32149-57-8 Commercial - Regular

Lithium Tertiary Butoxide 1907-33-1 Commercial - Campaign

Lithium Bis(trimethylsilyl)amide 4039-32-1 Commercial - Regular

Sodium Bis(trimethylsilyl)amide 1070-89-9 Commercial - Regular

Potassium Bis(trimethylsilyl)amide 40949-94-8 Commercial - Regular

Selenium Dioxide 7446-08-4 Commercial - Campaign

Vinyl Magnesium Bromide 1826-67-1 Commercial - Campaign

Diethyl Zinc 557-20-0 Developed in R&D

Cerium Chloride 7790-86-5 Developed in R&D

Sodium Cyanoborohydride 25895-60-7 Developed in R&D

Product List (2)

Category Product CAS Number Status

Phase Transfer Catalysts

Tetrabutyl Ammonium Bromide 1643-19-2 Commercial - Regular

Triethyl Benzyl Ammonium Chloride 56-37-1 Commercial - Regular

Methyl Trioctyl Ammonium Chloride 5137-55-3 Commercial - Campaign

Fine Chemicals

(Pyridine Derivatives)

2-Amino Pyridine 504-29-0 Commercial - Regular

3-Amino Pyridine 462-08-8 Commercial - Regular

4-Amino Pyridine 504-24-5 Commercial – Regular

2,3-Diamino Pyridine 452-58-4 Commercial - Campaign

2,6-Diamino Pyridine 141-86-6 Commercial - Regular

2-Amino 3-Hydroxy Pyridine 16867-03-1 Developed in R&D

2-Amino 3-Methyl Pyridine 1603-40-3 Commercial - Campaign

2-Amino 4-Methyl Pyridine 695-34-1 Commercial - Regular

2-Amino 5-Methyl Pyridine 1503-41-4 Developed in R&D

2-Amino 6-Methyl Pyridine 1824-81-3 Commercial - Regular

2-Amino 5-Chloro Pyridine 1072-98-6 Commercial - Regular

Nasense Labs Private Limited

Product List (3)

Category Product CAS Number Status

Fine Chemicals

(Pyridine Derivatives)

4-Dimethyl Amino Pyridine (DMAP) 1122-58-3 Commercial - Regular

2-Acetyl Pyridine 1122-62-9 Commercial - Campaign

3-Acetyl Pyridine 350-03-8 Commercial - Regular

4-Acetyl Pyridine 1122-54-9 Commercial - Campaign

Pyridine 3-(Acetic Acid) 501-81-5 Commercial - Regular

Pyridine 2-Methanol 586-98-1 Commercial - Campaign

Pyridine 3-Methanol 100-55-0 Commercial - Campaign

Pyridine 4-Methanol 586-95-8 Commercial - Campaign

2-Amino Methyl Pyridine 3731-51-9 Developed in R&D

3-Amino Methyl Pyridine 3731-52-0 Developed in R&D

4-Amino Methyl Pyridine 3731-53-1 Developed in R&D

Pyridine 2-Aldehyde 1121-60-4 Developed in R&D

Pyridine 3-Aldehyde 500-22-1 Developed in R&D

Pyridine 4-Aldehyde 872-85-5 Developed in R&D

2-Chloro Pyridine 109-09-1 Commercial - Campaign

Nasense Labs Private Limited

Nasense Labs Private Limited

Product List (4)

Category Product CAS Number Status

Fine Chemicals

(Pyridine Derivatives)

2,6-Dichloro Pyridine 2402-78-0 Commercial - Campaign

2-Chloro 5-Methyl Pyridine 18368-64-4 Developed in R&D

2-Chloro Nicotinic Acid 2942-59-8 Developed in R&D

2-Bromo Pyridine 109-04-6 Commercial - Campaign

Isonicotinic Acid 55-22-1 Commercial - Campaign

Isonipecotic Acid 498-94-2 Commercial - Campaign

Azacyclonol

115-46-8

(HCI – 1798-50-1)

Commercial - Campaign

Pharmaceutical Intermediates

Dextromethorphan Intermediate

3-Methoxymorphinan

1531-25-5 Commercial - Regular

Risperidone Intermediate 1 (6-fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride)

84163-13-3 Commercial - Regular

Risperidone Intermediate 2 (3-(2-chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido-(1,2-a)pyrimidine-4-one hydrochloride)

93076-03-0 Commercial - Regular

Paliperidone Intermediate (3-2-(2-chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido-[1,2-a]-pyrimidine-4- one)

130049-82-0 Commercial - Campaign

Nasense Labs Private Limited

Product List (5)

Category Product CAS Number Status

Pharmaceutical Intermediates

Iloperidone Intermediate (1-[4-(3-Chloropropoxy)-3-methoxyphenyl] ethanone)

58113-30-7 Commercial - Campaign

Future Products

Sodium Selenate 13410-31-0 Under Development

Sodium Selenite 10102-18-8 Under Development

Zinc Selenite 13597-46-1 Under Development

Selenium Sulfide 7488-56-4 Under Development

Sodium Iodide 7681-82-5 Ready for Pilot Testing

Sodium Metaperiodate 7790-28-5 Ready for Pilot Testing

Potassium Iodide 7681-11-0 Ready for Pilot Testing

Trimethyl Sulfoxonium Iodide 1774-47-6 Ready for Pilot Testing

Sodium Azide 26628-22-8 Under Development

Sodium Borohydride 16940-66-2 Under Development

Sodium Cyanide 143-33-9 Under Development

Sodium Methoxide 124-41-4 Under Development

Triphenyl Phosphine 603-35-0 Ready for Pilot Testing

Nasense Labs Private Limited

Leadership

Our Founder and Chairman, Mr. GRK Raju is a Chemical Engineer from Osmania University. He is a Post

Graduate Scholar in Safety Engineering and Management, with an experience of over 40 years in the Chemical

and Bulk Drug industry.

Our Director of Research and Process Development, Mr. YP Rao is a renowned specialist in Process Design

and Optimization. Over the past 35 years, he has been a key contributor to the process engineering

developments undertaken by companies like Lupin, Cipla, Siri’s, Plant Organics, Kopalle and Dr. Reddy’s.

Our Managing Director, Mr. Goutam Gottumukkala, is a Post Graduate Scholar in Pharmaceutical

Biotechnology, from the University of Pennsylvania, Philadelphia.

Core Competency

Processes Capabilities

Acid Chlorination, Acrylate Chemistry, Acylation, Allylation, Amoxidation

Catalytic Hydrogenation, Chichibabin Amination

Chemistry & Manufacture of Phase Transfer Catalysts

DMS Chemistry

Epichlorohydrin Chemistry, Esterification

Free Radical Polymerizations

Hydrazine Chemistry

Liquid and Vapor Phase Oxidation

Maleic Chemistry, Methylations

Pyridine Chemistry

Sodamide Chemistry, Sulfonation (SO3 Chemistry)

Process Specialties

Operating Temperatures (-40oC to +600oC)

High Pressure Hydrogenation (Up to 350 psi)

High Temperature/High Vacuum Distillation (300oC)

Sonochemistry (Ultrasound)

High Melting Point Distillation

Solids Handling (Filtration/Drying/Flaking)

Short Path Distillation for High Boiling Compounds

Purification using Sublimate Condenser

Key Strengths

In-house Design and Fabrication of Specialized Equipment

In-house R&D Department - High Process Efficiency and Optimization

Forward and Backward Integration of Process and Product Lines

Quality Centric Approach

Complex Technology, Application and Process Capabilities

Important Company Details

Nasense Labs Private Limited

Details of Manufacturing Facility

GPS Coordinates +17° 31' 22.46", +78° 27' 8.02"

Total Area 7770 m2

Constructed Area 7094 m2

Total Installed Reactor Volume 115.66 KL

Number of Reactors 34 (SSR + GLR + MSR)

Other Important Equipment Agitated Nutsche Filter

Autoclave

Ball Mill

Candle Filter

Centrifuge

Extractor and Settler

High Vacuum Distillation Unit

Leaf and Line Filters

Pressure Filter

Pulverizer

Ribbon Blender

Rotary Cone Vacuum Dryer

Short Path Distillation Unit

Sublimate Condenser

Tray and Vacuum Tray Dryers

R&D and QC Equipment

Other Details

Number of Permanent Employees 115

Number of Contract Workers 100 - 150

Sales in 2012-2013 33.6 Crore INR

Certifications

ISO 9001:2008

Alliances

We have entered a strategic alliance with Nagarjuna Agrichem Limited, one of the market leaders in

the Indian Agrochemical Industry. They are a key stakeholder in our organization.

We are closely associated with Yasham Specialty Ingredients Private Limited. They provide us with an

additional marketing front to cater to International Markets.

We also have a long-term association with Asepsis Pharmaceuticals, a leading International

manufacturer of Generic Pharmaceuticals, for the sale of locally-manufactured Dextromethorphan

Hydrobromide (and its derivatives) in China.

Key Customers

Nasense Labs Private Limited

Review of Major Events

March 26, 2002 to June 2007

Incorporation as USP Organics Private Limited

Trading Activity in Fine Chemicals

July 2007 to February 2010

Construction of Two Blocks (Once each for Sodium Hydride and Sodium Amide)

March 9, 2010

Commencement of Commercial Production (Sodium Line)

April 2010 to May 2012

R&D on the Selenium Line of Compounds

R&D on Pharmaceutical Ingredients

Construction of Pharma Block

Process Optimization

May 2012

Commercial Production of Pharmaceutical Intermediates (Risperidone)

Strategic Alliance with Nagarjuna Agrichem Limited

June 2012

Name Change to Nasense Labs Private Limited (June 26, 2012)

Commercial Production of Pharmaceutical APIs (Dextromethorphan)

July to December 2012

R&D on the Iodine Line of Compounds

Association with Yasham Chemphar Private Limited

Association with Asepsis Pharmaceuticals

Audit Qualification by Sun Pharma

Early 2013

ISO 9001:2008 Certification (January 15, 2013)

First Export Order (Risperidone Intermediates - Esteve Quimica, Spain)

R&D on the Pyridine Line of Compounds

R&D on Phase Transfer Catalysts

Recent Developments

Process and Equipment Optimization for the Manufacture of Pyridine based Products

R&D for Extraction of Recovered Iodine

Audit Qualification by Neuland Labs, IPCA, MYLAN and Dr. Reddy’s Laboratories

Commercial Production of Pyridine Line of Compounds & Phase Transfer Catalysts

Audit Processing by 3 Japanese Companies (Kureha, Kanematsu and Dainippon Sumitomo)

Future Plans

Commercial Production of Iodine Line of Compounds

Commercial Production of Selenium Line of Compounds

Setting up an Iodine Recovery System

Setting up a Hydrogen Plant for Captive Consumption

Nasense Labs Private Limited

Notes

Nasense Labs Private Limited

www.nasense.com

Thank you very much for your interest in our company.

Please visit our website for additional information on our activities.

We are looking forward to doing business with you!

Tools for Organic Synthesis – Phase Transfer Catalysts – Fine Chemicals – Pharmaceutical Ingredients