Nasense Labs Private Limitednasense.com/Nasense pdfs/corporatebrochure.pdf · Our core products are...
Transcript of Nasense Labs Private Limitednasense.com/Nasense pdfs/corporatebrochure.pdf · Our core products are...
Email: [email protected]
Manufacturing Facility Plot Numbers 24 & 25 SV Cooperative Industrial Estate Jeedimetla, Quthubullapur (M)
Hyderabad – 500 055 Andhra Pradesh, India +91 40 64643570 / 71
Nasense Labs Private Limited
Tools for Organic Synthesis – Phase Transfer Catalysts – Fine Chemicals – Pharmaceutical Ingredients
Corporate Office Plot Number D-70
Madhuranagar (Behind Vellanki Foods)
Hyderabad – 500 038 Andhra Pradesh, India
+91 40 64643572 / 73 / 74
Website: www.nasense.com
Fax: +91 40 23713572
We are Nasense Labs, an established manufacturer of Fine Chemicals and Pharmaceutical Ingredients.
Our company was originally incorporated as USP Organics Private Limited, in the year 2002. After
an extensive rebranding project, it was renamed as Nasense Labs Private Limited, effective from
June 26, 2012.
Our core products are a set of high-precision tools for organic syntheses, used in a variety of
chemical processes across multiple industry sectors. We specialize in 100% conversion reactions,
and are dedicated to the development of clean, flexible and quality-specific production systems.
We are highly competent in the manufacture of Sodium based products, and have recently
developed systems for a number of Iodine and Selenium based products. We also specialize in the
manufacture of Pyridine Derivatives and Phase Transfer Catalysts, and have the capability to work
on a wide range of molecules in these categories.
Although we are a recent entrant in the pharmaceutical industry, our engineering and process
design competences enable us to produce high quality pharmaceutical ingredients in a maximally
efficient, reduced effluent-load system.
Tools for Organic Synthesis – Phase Transfer Catalysts – Fine Chemicals – Pharmaceutical Ingredients
Nasense Labs Private Limited
Product List (1)
Category Product CAS Number Status
Tools for Organic Synthesis
Sodium Hydride (60% in LLP Oil) 7646-69-7 Commercial - Regular
Sodium Amide 7782-92-5 Commercial - Regular
Sodium Tertiary Butoxide 865-48-5 Commercial - Regular
Magnesium Tertiary Butoxide 32149-57-8 Commercial - Regular
Lithium Tertiary Butoxide 1907-33-1 Commercial - Campaign
Lithium Bis(trimethylsilyl)amide 4039-32-1 Commercial - Regular
Sodium Bis(trimethylsilyl)amide 1070-89-9 Commercial - Regular
Potassium Bis(trimethylsilyl)amide 40949-94-8 Commercial - Regular
Selenium Dioxide 7446-08-4 Commercial - Campaign
Vinyl Magnesium Bromide 1826-67-1 Commercial - Campaign
Diethyl Zinc 557-20-0 Developed in R&D
Cerium Chloride 7790-86-5 Developed in R&D
Sodium Cyanoborohydride 25895-60-7 Developed in R&D
Product List (2)
Category Product CAS Number Status
Phase Transfer Catalysts
Tetrabutyl Ammonium Bromide 1643-19-2 Commercial - Regular
Triethyl Benzyl Ammonium Chloride 56-37-1 Commercial - Regular
Methyl Trioctyl Ammonium Chloride 5137-55-3 Commercial - Campaign
Fine Chemicals
(Pyridine Derivatives)
2-Amino Pyridine 504-29-0 Commercial - Regular
3-Amino Pyridine 462-08-8 Commercial - Regular
4-Amino Pyridine 504-24-5 Commercial – Regular
2,3-Diamino Pyridine 452-58-4 Commercial - Campaign
2,6-Diamino Pyridine 141-86-6 Commercial - Regular
2-Amino 3-Hydroxy Pyridine 16867-03-1 Developed in R&D
2-Amino 3-Methyl Pyridine 1603-40-3 Commercial - Campaign
2-Amino 4-Methyl Pyridine 695-34-1 Commercial - Regular
2-Amino 5-Methyl Pyridine 1503-41-4 Developed in R&D
2-Amino 6-Methyl Pyridine 1824-81-3 Commercial - Regular
2-Amino 5-Chloro Pyridine 1072-98-6 Commercial - Regular
Nasense Labs Private Limited
Product List (3)
Category Product CAS Number Status
Fine Chemicals
(Pyridine Derivatives)
4-Dimethyl Amino Pyridine (DMAP) 1122-58-3 Commercial - Regular
2-Acetyl Pyridine 1122-62-9 Commercial - Campaign
3-Acetyl Pyridine 350-03-8 Commercial - Regular
4-Acetyl Pyridine 1122-54-9 Commercial - Campaign
Pyridine 3-(Acetic Acid) 501-81-5 Commercial - Regular
Pyridine 2-Methanol 586-98-1 Commercial - Campaign
Pyridine 3-Methanol 100-55-0 Commercial - Campaign
Pyridine 4-Methanol 586-95-8 Commercial - Campaign
2-Amino Methyl Pyridine 3731-51-9 Developed in R&D
3-Amino Methyl Pyridine 3731-52-0 Developed in R&D
4-Amino Methyl Pyridine 3731-53-1 Developed in R&D
Pyridine 2-Aldehyde 1121-60-4 Developed in R&D
Pyridine 3-Aldehyde 500-22-1 Developed in R&D
Pyridine 4-Aldehyde 872-85-5 Developed in R&D
2-Chloro Pyridine 109-09-1 Commercial - Campaign
Nasense Labs Private Limited
Nasense Labs Private Limited
Product List (4)
Category Product CAS Number Status
Fine Chemicals
(Pyridine Derivatives)
2,6-Dichloro Pyridine 2402-78-0 Commercial - Campaign
2-Chloro 5-Methyl Pyridine 18368-64-4 Developed in R&D
2-Chloro Nicotinic Acid 2942-59-8 Developed in R&D
2-Bromo Pyridine 109-04-6 Commercial - Campaign
Isonicotinic Acid 55-22-1 Commercial - Campaign
Isonipecotic Acid 498-94-2 Commercial - Campaign
Azacyclonol
115-46-8
(HCI – 1798-50-1)
Commercial - Campaign
Pharmaceutical Intermediates
Dextromethorphan Intermediate
3-Methoxymorphinan
1531-25-5 Commercial - Regular
Risperidone Intermediate 1 (6-fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride)
84163-13-3 Commercial - Regular
Risperidone Intermediate 2 (3-(2-chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido-(1,2-a)pyrimidine-4-one hydrochloride)
93076-03-0 Commercial - Regular
Paliperidone Intermediate (3-2-(2-chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido-[1,2-a]-pyrimidine-4- one)
130049-82-0 Commercial - Campaign
Nasense Labs Private Limited
Product List (5)
Category Product CAS Number Status
Pharmaceutical Intermediates
Iloperidone Intermediate (1-[4-(3-Chloropropoxy)-3-methoxyphenyl] ethanone)
58113-30-7 Commercial - Campaign
Future Products
Sodium Selenate 13410-31-0 Under Development
Sodium Selenite 10102-18-8 Under Development
Zinc Selenite 13597-46-1 Under Development
Selenium Sulfide 7488-56-4 Under Development
Sodium Iodide 7681-82-5 Ready for Pilot Testing
Sodium Metaperiodate 7790-28-5 Ready for Pilot Testing
Potassium Iodide 7681-11-0 Ready for Pilot Testing
Trimethyl Sulfoxonium Iodide 1774-47-6 Ready for Pilot Testing
Sodium Azide 26628-22-8 Under Development
Sodium Borohydride 16940-66-2 Under Development
Sodium Cyanide 143-33-9 Under Development
Sodium Methoxide 124-41-4 Under Development
Triphenyl Phosphine 603-35-0 Ready for Pilot Testing
Nasense Labs Private Limited
Leadership
Our Founder and Chairman, Mr. GRK Raju is a Chemical Engineer from Osmania University. He is a Post
Graduate Scholar in Safety Engineering and Management, with an experience of over 40 years in the Chemical
and Bulk Drug industry.
Our Director of Research and Process Development, Mr. YP Rao is a renowned specialist in Process Design
and Optimization. Over the past 35 years, he has been a key contributor to the process engineering
developments undertaken by companies like Lupin, Cipla, Siri’s, Plant Organics, Kopalle and Dr. Reddy’s.
Our Managing Director, Mr. Goutam Gottumukkala, is a Post Graduate Scholar in Pharmaceutical
Biotechnology, from the University of Pennsylvania, Philadelphia.
Core Competency
Processes Capabilities
Acid Chlorination, Acrylate Chemistry, Acylation, Allylation, Amoxidation
Catalytic Hydrogenation, Chichibabin Amination
Chemistry & Manufacture of Phase Transfer Catalysts
DMS Chemistry
Epichlorohydrin Chemistry, Esterification
Free Radical Polymerizations
Hydrazine Chemistry
Liquid and Vapor Phase Oxidation
Maleic Chemistry, Methylations
Pyridine Chemistry
Sodamide Chemistry, Sulfonation (SO3 Chemistry)
Process Specialties
Operating Temperatures (-40oC to +600oC)
High Pressure Hydrogenation (Up to 350 psi)
High Temperature/High Vacuum Distillation (300oC)
Sonochemistry (Ultrasound)
High Melting Point Distillation
Solids Handling (Filtration/Drying/Flaking)
Short Path Distillation for High Boiling Compounds
Purification using Sublimate Condenser
Key Strengths
In-house Design and Fabrication of Specialized Equipment
In-house R&D Department - High Process Efficiency and Optimization
Forward and Backward Integration of Process and Product Lines
Quality Centric Approach
Complex Technology, Application and Process Capabilities
Important Company Details
Nasense Labs Private Limited
Details of Manufacturing Facility
GPS Coordinates +17° 31' 22.46", +78° 27' 8.02"
Total Area 7770 m2
Constructed Area 7094 m2
Total Installed Reactor Volume 115.66 KL
Number of Reactors 34 (SSR + GLR + MSR)
Other Important Equipment Agitated Nutsche Filter
Autoclave
Ball Mill
Candle Filter
Centrifuge
Extractor and Settler
High Vacuum Distillation Unit
Leaf and Line Filters
Pressure Filter
Pulverizer
Ribbon Blender
Rotary Cone Vacuum Dryer
Short Path Distillation Unit
Sublimate Condenser
Tray and Vacuum Tray Dryers
R&D and QC Equipment
Other Details
Number of Permanent Employees 115
Number of Contract Workers 100 - 150
Sales in 2012-2013 33.6 Crore INR
Certifications
ISO 9001:2008
Alliances
We have entered a strategic alliance with Nagarjuna Agrichem Limited, one of the market leaders in
the Indian Agrochemical Industry. They are a key stakeholder in our organization.
We are closely associated with Yasham Specialty Ingredients Private Limited. They provide us with an
additional marketing front to cater to International Markets.
We also have a long-term association with Asepsis Pharmaceuticals, a leading International
manufacturer of Generic Pharmaceuticals, for the sale of locally-manufactured Dextromethorphan
Hydrobromide (and its derivatives) in China.
Key Customers
Nasense Labs Private Limited
Review of Major Events
March 26, 2002 to June 2007
Incorporation as USP Organics Private Limited
Trading Activity in Fine Chemicals
July 2007 to February 2010
Construction of Two Blocks (Once each for Sodium Hydride and Sodium Amide)
March 9, 2010
Commencement of Commercial Production (Sodium Line)
April 2010 to May 2012
R&D on the Selenium Line of Compounds
R&D on Pharmaceutical Ingredients
Construction of Pharma Block
Process Optimization
May 2012
Commercial Production of Pharmaceutical Intermediates (Risperidone)
Strategic Alliance with Nagarjuna Agrichem Limited
June 2012
Name Change to Nasense Labs Private Limited (June 26, 2012)
Commercial Production of Pharmaceutical APIs (Dextromethorphan)
July to December 2012
R&D on the Iodine Line of Compounds
Association with Yasham Chemphar Private Limited
Association with Asepsis Pharmaceuticals
Audit Qualification by Sun Pharma
Early 2013
ISO 9001:2008 Certification (January 15, 2013)
First Export Order (Risperidone Intermediates - Esteve Quimica, Spain)
R&D on the Pyridine Line of Compounds
R&D on Phase Transfer Catalysts
Recent Developments
Process and Equipment Optimization for the Manufacture of Pyridine based Products
R&D for Extraction of Recovered Iodine
Audit Qualification by Neuland Labs, IPCA, MYLAN and Dr. Reddy’s Laboratories
Commercial Production of Pyridine Line of Compounds & Phase Transfer Catalysts
Audit Processing by 3 Japanese Companies (Kureha, Kanematsu and Dainippon Sumitomo)
Future Plans
Commercial Production of Iodine Line of Compounds
Commercial Production of Selenium Line of Compounds
Setting up an Iodine Recovery System
Setting up a Hydrogen Plant for Captive Consumption
Nasense Labs Private Limited