Nano Fusion Technologies Overview)
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Transcript of Nano Fusion Technologies Overview)
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Nano Fusion Technologies, Inc.
April 2009
Introduction to
micro Electro-osmotic (EO) pumps
& micro-fluidic technologies
Nano Fusion Technologies, Inc. Founders and Managements
Tihiro Ohkawa (Founder)
Masana Nishikawa (Founder)
Ichiro Yanagisawa (CEO/CTO)
Masataka Ogawa (VP, Business Development)
Major Shareholders (Founders & VCs)
Yasuda Enterprise Development Co., Ltd (Japan)
Conduit Ventures Limited (UK)
4 Japanese VCs
Founded: March 15, 2004
Capital: 229,750,000 yen
Headquarters: 2-21-7, Naka-cho, Meguro-ku, Tokyo, Japan
Laboratory: B-M202 Collaborative Research Bldg. (CCR)Institute of Industrial Science, the University of Tokyo
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Objective
NFT Objective: Offer micro fluid delivery solutions with unique micro pumps and micro-fluidic control devices to advance bio-science and micro-electronics functions.
Major Technologies: Micro electro-osmotic pump (Micro EO pumps)
Micro-fluidic control devices and systems
Application Area: Bio-Science, Environmental and Chemical Applications
mTAS / Analytical device
Pipetting / Dispensing
Drug delivery (infusion) Micro Electronics
Micro Fuel Cell & others
Industrial (lubrication, etc.)
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Principle of micro EO pump- Electro-osmotic Pump -
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Liquid
Porous
ceramic
disc
(dielectric
material)
Liquid
Electrodes
Voltage
Nozzle Pumping
EOF
Inside ceramic disc
Ele
ctric
field
Liquid
Porous
material
Interface
Ele
ctric
field
Flo
w
Dielectric material (Ceramics)
I. Negative charges on the dielectric material surface.
II. Excessive positive charges generated in the liquid
near the liquid-ceramics interface.
III. The applied electric field would force the positively
charged liquid layer to flow, that drags the whole
liquid.
Electro-osmotic flow (EOF)
Electro-osmotic Flow (EOF)-generating mechanism Liquid
Ceramic particle
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Features of Micro EO pump
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Features of Micro EO pump
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Typical pump performances
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RP3-N1/N2
RP5A-RL-N311/N610
RP5A-SP-N311/N610
Overall Coverage
Flow Rate (mL/min) Pressure (kPa)
7B-SP-N311/N610
LFHP
10-1 1 10 102 103 10 102 1031
RP5A-RL (evaluation sample)
Model RP5A-RL-N311 RP5A-RL-N610
Pumping principle1) Electro-osmosis
Max.Flow rate2)
@DC 24V5)
110μ L/min 190μ L/min
Max.Pressure3) 140 kPa 110 kPa
Power
consumption4)
13 mW 100mW
Working liquid Methanol De-ionized water
Material Polypropylene(Body・Nozzle・Reservior)
Size Diameter 8mm,length 3.5mm(Body)
Reservior capacity 1.2mL
Weight 0.5g
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Performance of RP5A-RL-N311
0
20
40
60
80
100
120
140
160
0 50 100 150 200
12V
18V
24V
30V
Performance of RP5A-RL-N610
0
50
100
150
200
250
300
0 50 100 150
Back pressure (kPa)
Flo
w r
ate
(μL/m
in)
12V
18V
24V
30V
Back pressure (kPa)
Flo
w r
ate
(μL/m
in)
LFHP (evaluation sample)- For high pressure or extremely low flow rate -
Model LFHP
Pumping principle1) Electro-osmosis
Max.Flow rate2)
@DC 60V5)
8μL/min
Max.Pressure3) 2000kPa
Power consumption4) 15mW
Working liquid De-ionized water
Material PPS
Body size Diameter 10.3mm,length 27.3mm
Nozzle port Upchurch NanoPort Assemblies
F-333Nx
Nozzle fitting Upchurch NanoPort Assemblies
N-333-01
Weight 1.8g
1) High pressure performance up to 2,000kPa (at 60 Volts)
2) Extremely low flow rate (around 100 nL/min)
3) Standard fitting design compatible with Upchurch fitting
4) Extendable reservoir design
Working liquid:
De-ionized water
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Performance of LFHP
0
1
2
3
4
5
6
7
8
9
0 1000 2000 3000
Back pressure (kPa)
Flo
w r
ate
(μL/m
in)
24V
60V
Model PS-PWM-24 PS-PWM4C-24
Output voltage1) 24V max
Duty ratio 0~100%
Pulse-frequency Variable (10~2000Hz)
Resolution of voltage 6mV
Power supply USB bus power AC adaptor
Input 100-240V 50/60Hz 0.3A
Output DC5V 2A
Output current 50mA max 50mAmax/1 channel
Number of I/O channel 1 4
Size(W×D×H) 85×55×21mm 85×55×48mm
Enable stable micro-flow
by micro Electro-osmotic pump
1) PWM power source
2) Easy operation from Personal Computer
3) Built-in Feedback Control Function
PWM Power Source and Controller
for Micro EO Pump (PS-PWM-24)
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Evaluation Kits for micro EO pump
Power supply PS-PWM4C-24
FilterLFHP
Reservoir
Reservoir
Flow sensor LG16-0025AConnecter
Connecter
Low flow/High pressure kits EVK-001 formation
Power supply PS-PWM-24
Flow sensor LG16-1000A
RP20-SP
Reservoir for RP20-SP
Tube (Teflon)
Tube (Teflon)
High flow kits EVK-003 formation
Evaluation Kits for full EO pump testing
Include all necessary components (pumps, power supply, flow sensor,
reservoirs and so on)
Evaluation Kits for different flow rate ranges Low flow/High pressure kits (EVK-001) 0.1-1.5μL/min (-2000kPa)
Middle flow kits (EVK-002) 5-50μL/min
High flow kits (EVK-003) 100-1000μL/min
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EO Pumps on a Micro-Channel Chip
Basic Concept
Direct mount on micro-channel chips (Pump-on-chip)
Integrated pump (Reservoir-on-pump)
EO Pump
Reservoir
Micro-channel chip
Less redundant space
Less sample fluid
Precise flow rate &
flow amount control
EO pump applications
for Microfluidics I
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EO pump applications
for Microfluidics II
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Thank You
Nano Fusion Technologies, Inc.Headquarters: (Mailing address)
Nano Fusion Technologies, Inc.
2-21-7 Naka-cho, Meguro-ku, Tokyo 153-0065
JAPAN
e-mail: [email protected]
Website: http://www.nft-eop.co.jp/
Laboratory:
B-M202 Collaborative Research Bldg. (CCR)
Institute of Industrial Science, the University of Tokyo
4-6-1 Komaba, Meguro-ku, Tokyo 153-8505
JAPAN
TEL: +81-3-5452-6619 FAX: +81-3-5452-6620
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