MVTCP Clinical Trials Core Enrollment to Clinical Research ...€¦ · Committee, Cancer...
Transcript of MVTCP Clinical Trials Core Enrollment to Clinical Research ...€¦ · Committee, Cancer...
MMC, VICC & TSU: Partners in Eliminating Cancer Health Disparities
Meharry and Vanderbilt become one of the
first Cancer Partnerships supported by the
NCI U54 grant mechanism
MVTCP continues to grow. The partnership
has submitted a competitive renewal and will
expand training to high school students.
TSU becomes a full partner and the MVTCP
becomes the second Triad in the PACHE.
TSU brings new investigators and
undergraduate students.
Tennessee State (TSU) joins the MVCP as a
collaborator, expanding the partnerships
research into Community Engaged Research
Meharry and Vanderbilt form a partnership in
response to a supplement to the CCSG grant.
Our Cancer Partnership has matured and developed successful
collaborative interactions based on excellence, true reciprocity, and
mutual benefit. As a triad, we aim to amplify the cancer research
capabilities in the greater Nashville community, improve outcomes in the
diagnosis and treatment of cancer in minority and underserved
communities, minimize measurable disparities among minority
populations, and fortify collaborations among the partners. During the past
5 years, we have made significant progress toward achieving our mission
through: 1) recruiting 6 new faculty members; 2) training 7 PhD and MPH
candidates at MMC and TSU; 3) training 4 oncology fellows at MMC/
VICC; 4) providing summer cancer research experience to 18
undergraduates at TSU and 22 medical students at MMC and VICC; and
5) increasing clinical trials access. Our clinical trials core accrued 350
patients (57% African American) and increased the number of open
clinical trials in both cancer treatment and control studies (50% over two
years). Our program evaluation structure includes the monitoring by the
Internal Advisory Committee, the Program Steering Committee, and the
As we look ahead, we plan to:
1. Fund state-of-the-art research projects to increase and stabilize the
competitive cancer research capability of MMC and TSU;
2. Increase the cancer disparities research portfolio at VICC;
3. Expand cancer research education program to include high school
students;
4. Implement a hybrid outcomes-logic-model and a pure outcomes-based
process to evaluate the Partnership’s progress;
5. Enhance clinical trials access for minority populations served by
Nashville General Hospital (NGH)/MMC.
Lourdes Estrada, Ph.D.1*
, Ketia Barnes, B.S.2*
, David E. Danner, J.D.3, W. Wayne Green, B.S.
2, Samuel E. Adunyah, Ph.D.
2,
Baqar A. Husaini, Ph.D.3, Philip E. Lammers, M.D.
2, Harold L. Moses, M.D.
1, Ann Richmond, Ph.D.
1, Margaret Whalen, Ph.D.
3
*Presenting Co-authors; 1Vanderbilt Ingram Cancer Center, Nashville, TN;
2Meharry Medical College, Nashville, TN;
3Tennessee State University, Nashville, TN
Acknowledgments
Education & Training
Future Directions
Clinical Trials Community Outreach Introduction
Partnership History
Activities
Engagement with populations affected by cancer health disparities through Community Advisory Board (CAB), Teen and Parent (TAP) Committee, Cancer Survivorship Committee, listserv and outreach to underserved communities.
Provision of tangible support to MVTCP-funded and emerging projects (e.g., expert consultation, recruitment, protocol development & review), community organizations and coalitions, and the NCI National Outreach Network in cancer disparities efforts.
Mentoring students and trainees in Community Engaged Research and culturally-appropriate outreach strategies.
Administrative supplement to expand evaluation of HPV vaccine social marketing intervention
Hosting of two radio health programs reaching African American and Hispanic audiences, providing 100 hours of health information programming and cancer researcher guest interviews each year.
Accomplishments
Awarded NCORP grant partnership with Memphis Baptist Healthcare System
Successful Alliance Cooperative Group Site Audit and WFU Site Audit
Nashville General Hospital was awarded Commission on Cancer 3-Year Accreditation with a Commendation for Clinical Trials Program and Accruals
Hired a 2nd medical oncologist, Dr. Robin Jacob from Howard University and a surgical oncologist, Dr. Sandeep Anantha from Michigan
This material is based upon work supported by the National Cancer Institute PACHE program grant numbers 5U54CA163069 (MMC), 5U54CA163072 (VICC), and 5U54CA163066 (TSU).
Research Activity
Recruitment Basic Science Population Science Clinical Science
Anil Shanker, MS,
PhD (MMC)
Rebecca Selove, MPH,
PhD (TSU)
Philip Lammers, MD,
MSCI (MMC)
Jamaine Davis, PhD
(MMC)
Hilary Tindle, MD, MPH
(VICC)
Sandeep Anantha, MD
(MMC)
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2011 2012 2013 2014 2015 2016 CancerControlStudies
CancerTreatment
Trials
MVTCP Clinical Trials Core Enrollment to Clinical Research 2011-2016
Caucasian African-American Hispanic Other
2011 - 2015
Full Projects: Supported a total of four (4) full projects - two for three years on breast cancer and prostate cancer and two for two years on cancer survivorship and lung cancer .
Pilot Projects: Supported a total of two (2) pilot projects - one for three years on HPV vaccine and the other for two years on breast cancer.
Shared Resource Cores: Support four (4) Shared Resource Cores:
Biostatistics Core
Translational Pathology Core
Clinical Trials Core
Community Outreach Core
Grants: Awarded over 20 grants including 3 R01s, 2 SC1s, and 2 R21s
Publications: 150+ peer-reviewed publications
Meharry (MMC) - Vanderbilt (VICC) - Tennessee State (TSU) Cancer Partnership
Drs. Pam Hull (l) and Lourdes Estrada from VU on
Progress & Wellbeing (Progreso y Bienestar) on La
Nueva Activa 1240 AM
Training Opportunities
Undergraduates: Summer Research Experience; Introduction to Cancer
Biology Course, Mentored Behavioral Science Training in Cancer
Disparities
Masters of Public Health Students: Summer Research Experience;
Graduate Internship with Community Outreach Core
Doctoral Students: Pre-doctoral training support
Medical Students: Summer Research Experience
Postgraduates: Oncology Fellowship with Clinical Trials Core