More than 11 million confirmed COVID-19 cases worldwide ...€¦ · Prof. Harry van Goor Dr. Kiran...
Transcript of More than 11 million confirmed COVID-19 cases worldwide ...€¦ · Prof. Harry van Goor Dr. Kiran...
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Project PROSPER – Development of a PROactive Symptom and social Engagement Wearable trackeR for communities
Arun Sethuraman, Founder & CEO | [email protected] | +1.617.520.4447 |+65.9119.2989
More than 11 million confirmed COVID-19 cases worldwide, and 500,000+ deaths
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About 2 in 3 patients are unaware of COVID-19 symptoms, and they receive medical attention significantly late
Yale New Haven Health: Influenza (Flu) vs Coronaviruses. (n.d.). Retrieved June 30, 2020, from https://www.ynhhs.org/patient-care/urgent-care/flu-or-coronavirus
1. Patients are most infectious during first week, when they are only mildly symptomatic
2. ~20% develop severe pneumonia
3. ~80% of patients who require intubation or mechanical ventilation eventually die
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Early identification of symptoms is crucial for isolating and treating COVID-19 patients. Unfortunately, long term care facilities are woefully inadequate to deal with the crisis
Yang, X., Yu, Y., Xu, J., Shu, H., Xia, J., Liu, H., . . . Shang, Y. (2020). Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: A single-centered, retrospective, observational study. The Lancet Respiratory Medicine, 8(5), 475-481. doi:10.1016/s2213-2600(20)30079-5
Covid-19 patients most infectious in 1st week of illness, but odds of transmission significantly reduced after 2nd week: S'pore study. (n.d.). Retrieved June 29, 2020, from https://www.todayonline.com/singapore/covid-19-patients-most-infectious-1st-week-illness-odds-transmission-significantly-reduced
Written by Josephine Moulds, F. (n.d.). People with mild or no symptoms could be spreading COVID-19. Retrieved June 29, 2020, from https://www.weforum.org/agenda/2020/03/people-with-mild-or-no-symptoms-could-be-spreading-covid-19/
Residents and staff live and work in small,
confined and crowded settings
A lot of staff work at multiple care facilities to
compensate for low wages
Nature of care work requires
physical contact
Elderly residents Residents with comorbidities+
~50%
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Reliable continuous patient monitoring system and a credible early warning method is an unmet need
Physiological, Social and Environmental factors form the basis of an effective early warning system.
Symptoms monitoring. Equivalent to, or better
than current standard of care
Rapid Contact Tracing and Enforcement of Quarantine
Orders
Identification Of Virus Clusters And Optimal Transmission
Conditions
+ +
Project PROSPER is the development of a PROactive Symptom and social Engagement Wearable trackeR for communities
A wearable device-enabled clinical decision support system to improve early detection and management of Infectious Disease epidemics like COVID-19
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Team Crely is an accomplished, diverse group of clinicians, scientists, engineers and MedTech executives who are passionate about our mission to make a difference to the patients
Prior to Crely, the team collectively has had 120 years of experience, 20 publications and 2 patents
Prof. Harry van Goor Dr. Kiran Agrawal-Harding Dr. Niki Kennedy
Scientific Advisory BoardCrely Leadership Team
Project PROSPER is an extension of Crely’s medical device enabled remote monitoring platform to improve surgical outcomes
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Purpose of EUREKA GlobalStars grant request is to complete Proof of Concept of the 360 degree clinical decision support system to improve early detection and management of COVID-19 and future Infectious Diseases.
Credits: CIMIT HealthTech Innovation Cycle
Technical
Regulatory
Market/ Bus.
Clinical
INVENTION TRANSLATION COMMERCIALIZATION
Need Idea PoC PoF PoV ICT VoS A&L Use SoC
Solid Line: Current State Dashed Line: Deliverables from Grant
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To accomplish our collective mission, we would like to have a dialog with a diverse group of potential partners to assess each other’s mission, motivation, strengths, synergies and gaps
# Partner Profile Role of Partner Desired Outcome1 Govt. bodies, Ministry of Health, Non-
profit foundations involved with population health and/or epidemic management
• Validate unmet need• Knowledge partner to customize solution
to the needs of the market• Integration of solution within existing
healthcare service delivery
• Conditional Letter of Intent (LoI) for joint commercialization
2 Universities, Research Centers, Healthcare Systems
• Validate unmet need• Knowledge partner to customize solution
to the clinical needs of the target indication
• Support with product development• Conduct Clinical Studies
• Development of joint IP from the project
• Clinical validation• Licensing agreement to
commercialize IP
3 Companies with Sensor and/or Machine Learning / AI related competencies
• Collaborate with Crely on technology and product development
• Rapid development of technology solutions
• Joint commercialization opportunity
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Crely won the award of Best Investment at the Harvard Business School 2019 New Venture
Competition-Asia Pacific
Potential to save tens of thousands of lives
With sensor data and clinical insights, additional business opportunities for data-related services
High barriers to entry for competition due to IP protection for sensors, and data acquisition lead
Exit options through robust M&A market with potential suitors from both healthcare and IT industries
Team Crely is at the right place, with the right people, and with the right solution to make an impact to the lives of patients and healthcare providers. We need your support.