1. Disease-specific treatment directions in CP Adam Kirton MD MSc FRCPC Associate Professor, Pediatrics and Clinical Neurosciences University of Calgary, Alberta Childrens Hospital Research Institute Brain Development Conference Vancouver 2013.09.29

2. Preterm GlobalTerm GlobalPreterm FocalTerm Focal 3. Preterm GlobalTerm GlobalPreterm FocalTerm Focal 4. Preterm GlobalTerm GlobalPreterm FocalTerm FocalWMI / EOPHIESTROKE (PVI)STROKE (ART)ACUTEDIAGNOSISLATEKNOWNRISK FACTORSUNKNOWNMAYBE NOTNORMAL BRAIN?YES 5. AIS-MCAPreterm FocalSTROKE (PVI)STROKE (ART) 6. STROKE (PVI)STROKE (ART) 7. STROKE (PVI)STROKE (ART) 8. STROKE (PVI)STROKE (ART) 9. STROKE (PVI)STROKE (ART) 10. NEUROPHYSIOLOGY OUTCOMES 11. STROKE (PVI)STROKE (ART) 12. Parental Outcomes Guilt, blame Future planning Programs, funding Access to informationAPSP Parental Outcome Measure 3 subscales, 31 items Consistent, reliable, validSTROKE (PVI)Bemister et, Canadian Stroke Congress 2012; European Psychology Conference 2013STROKE (ART) 13. www.cpssa.orgwww.iapediatricstroke.orgwww.brendonssmile.orgwww.canadianstrokenetwork.ca 14. WMI / EOPOL progenitorHIEPre OLSTROKE (PVI)Immature OLSTROKE (ART)Mature OL Back SA et al,J Neurosci. 2001 Volpe JJ. Lancet Neurology 2009 15. Preterm GlobalTerm GlobalPreterm FocalTerm Focal 16. Preterm GlobalTerm GlobalPreterm FocalTerm Focal