Mission and Vision Hepatitis C in Indiana Mission C... · Top Hepatitis C Risk Factors, by Percent*...

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10/24/2019 1 Hepatitis C in Indiana Deborah Nichols, MPH, MS Viral Hepatitis/Harm Reduction Program Director OUD ECHO Medical Co-Morbidity Sessions October 23, 2019 Mission and Vision Mission: To promote, protect, and improve the health and safety of all Hoosiers Vision: A healthier and safer Indiana How do you get it? Blood-to-Blood Hepatitis C is NOT transmitted How do you know you have it?

Transcript of Mission and Vision Hepatitis C in Indiana Mission C... · Top Hepatitis C Risk Factors, by Percent*...

Page 1: Mission and Vision Hepatitis C in Indiana Mission C... · Top Hepatitis C Risk Factors, by Percent* – Indiana, 2014-2018 Hepatitis C Lab Reporting Required • All positive screening

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Hepatitis C in Indiana

Deborah Nichols, MPH, MSViral Hepatitis/Harm Reduction Program Director

OUD ECHO Medical Co-Morbidity SessionsOctober 23, 2019

Mission and Vision

Mission:To promote, protect, and improve the health and safety of all Hoosiers

Vision:A healthier and safer Indiana

How do you get it?

Blood-to-Blood

Hepatitis C is NOT transmitted

How do you know you have it?

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Can it be treated or cured?Gelcaprevir and pibrentasvir

Mavyret

All genotypes

8 Weeks

$26,400

http://www.hepatitiswa.com.au/2017/08/01/new‐hep‐c‐treatments‐infographic/

$84,000‐$94,500

$94,500 $84,000 $83,320 $54,600

HCV Treatments

Generics now available for $24,500

What can happen if you don’t get it treated or cured?

How can you prevent others from getting it or giving it to others?

Abstain Be faithful

Choose Harm Reduction

Viral Hepatitis Surveillance

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26 people per day

in Indiana in 2018

received their first reactive HCV test

20 babies in Indiana

in 2018had a confirmed

surveillance case of

hepatitis C

13% 13% of all new cases of hepatitis C cases in Indiana in

2018 were identified in Department of Corrections

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119 140 181 236 359

1.82.1

2.7

3.5

5.4

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0.5

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5.5

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2014 2015 2016 2017 2018

Rate (per 100,000 population) 

Case Count

Acute HCV Cases Acute HCV Rate

200% increase

72 acute HCV cases in 2018 were co‐infected with HAV

Acute HCV & incidence rate/100,000 population, 2014-2018 - Indiana

Indiana ranked #3 in US for Acute HCV in 2017

Chronic HCV & incidence rate/100,000 population, 2014-2018, Indiana

6025 6732 7896 8306 7783

91.3101.7

119.0124.6

116.7

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Number of Reported Cases

Year

Cases Rates

The Indiana Hepatitis C Iceberg, 2018

*Klevens RM, Liu S, Roberts H, Jiles RB, Holmberg SD. Estimating acute viral hepatitis from nationally reported cases. Am J Public Health. 2014;104:482‐487.

1 Reported

Acute Case1

12.3 Estimated

Acute Infections*

359 Reported

Acute Cases

4,415Estimated

Acute Infections

Combined acute/chronic incident HCV cases by year of birth, diagnosed in 2010 and 2018,

Indiana

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Year of Birth

2010 2018

Baby Boomers Ages 18‐39

Top Hepatitis C Risk Factors, by Percent* – Indiana, 2014-2018

Hepatitis C Lab Reporting

Required• All positive screening

tests are reportable (antibody including rapid tests)

• All positive confirmatory tests are reportable (RNA, Genotype)

Desired• Pregnancy status for

women of child bearing age

• Bilirubin levels• ALT levels• Symptoms consistent

with VH• Negative antibody results• Negative RNA results

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410 IAC 1-2.5-75-76Increase in VH Program Staff

Irene Gonzalez

Hepatitis C Treatment

People who inject drugs represent a key population with the potential to sustain the HCV epidemic through continued transmission and thus SHOULD be targeted for treatment

Barriers to HCV Treatment for PWID

• At the patient level, misinformation about HCV and its treatment and the stigma related to substance use and HCV infection hinder linkage to care and limit patient interactions with the healthcare system

• At the provider level, misguided concerns about reinfection risk and adherence to HCV therapies

• At the system level, limited HCV treatment sites and restrictions on access to HCV therapy

Patient Level• At the patient level, innovative strategies are

needed to increase engagement in care for PWID. • Peer support by others who have experienced

substance use may be particularly effective at linking and supporting PWID through HCV treatment.

• HCV testing and linkage to HCV treatment in settings where PWID feel comfortable, potentially including sites where they currently access other services.

Provider Level• Trained non-specialists can independently

provide HCV treatment through ongoing collaboration using telemedicine platforms such as the Project ECHO model.

• It is critical to integrate harm reduction such as access to syringe programs into HCV care.

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System Level• Integrate HCV treatment into substance use

disorder treatment programs, public health clinics, syringe service programs, community-based organizations, and other sites providing services to PWID has the additional benefit of reducing barriers to HCV treatment.

• Innovative payment models at the system level may also improve treatment uptake..

*July 1, 2019 FSSA removed fibrosis restrictions for Medicaid patients for hepatitis C treatment

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Elimination!

To all the stakeholders in Indiana working to eliminate hepatitis!

Thank you

Deborah Nichols, MPH, MSViral Hepatitis/Harm Reduction Program DirectorDivision of HIV/STD/Viral [email protected]