MindMaze - Virtual reality solutions for stroke rehabilitation · In addition, it appears that...

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MindMaze - Virtual reality solutions for stroke rehabilitation Andrea Serino

Transcript of MindMaze - Virtual reality solutions for stroke rehabilitation · In addition, it appears that...

MindMaze - Virtual reality solutions for stroke rehabilitation

Andrea Serino

Copyright 2017, All Rights Reserved – MindMaze SALausanne, Switzerland

Mission

"To unlock human potential throughneurotechnology for learning and recovery"

Tej Tadi

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The Full Body Illusion, Lenggenhager, Tadi, Metzinger, Blanke, Science, 2007Blanke, Nat Neuroscie Rev, 2012, Blanke, Slater, Serino, Neuron, 2015

the experience of our self in space depends on the integration of multisensory bodily signals in the Peripersonal Space (PPS)

Rizzolatti et al., 1981; Graziano et al., 1994; Duhamel et al., 1998

Serino et al., Sci Rep, 2015; TICS, 2016; Givraz et al., Neuroimage 2017

Serino TICS, 2016

Noel et al, Cognition, 2016

Natural BSC

1. The Proprioceptive / Vestibular Constraint

2. The Visual Constraint

3. The PPS Constraint 4. The Embodiment Constraint

Two (main) mechanisms1. Multisensory integration

of bodily signals

Blanke, Slater, Serino, Neuron, 2015

2. Sensory-motor congruency

Wolpert & Ghahramani, Nat Neurosci, 2000Jeannerod, 2006; Blakemore & Frith, Curr Op Neurobiol, 2003

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Virtual Reality Solutions for Stroke Rehabilitation

Cost of stroke $43 billion in US and €29 billion in Europe, $10 billion for neurorehabilitation expenses.

2-4% of total health costs worldwide.

Stroke survivors in Western Europe, US & Asia= 5.5 million stroke incidences per year.

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AUTHORS’ CONCLUSIONSImplications for practiceWe found low quality evidence that virtual reality is a safe intervention that is effective at

improving arm function and activities of daily living (ADL) function following stroke.The evidence, albeit limited, suggests that improvements in function are greatest when agreater dose of therapy is delivered.In addition, it appears that patients with low to moderate upper limb impairment, andwho are less than six months post stroke, may have the greatest benefit.Gains made appear to be clinically significant with analyses showing reasonable effectsizes (that is, a small effect on upper limb function (standardised mean difference (SMD)0.29) and a small to moderate effect on ADL function (SMD 0.43)).

However, at present, there is significant heterogeneity between studies.

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Advantages of VR for rehabilitation

Increase dose: intensity and duration

Increase motivation

Administering fully-controlled exercises – thus maximizing recovery

Reduce costs

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MindMotion PRO

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MindMotion GO

Continuum of Care

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MindMotion GO

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Distal upper limb Proximal upper limb Trunk Lower limb

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MindMotion GO

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MindMotion GO

the MASK

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the MASK

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Lausanne

Chemin de Roseneck 5 1006 Lausanne, Switzerland

[email protected]+41 (0)21 552 0801

San Francisco

1161 Mission St.Office 434San Francisco, CA 94103

[email protected]+1 (323) 505 8461

Zurich

Technoparkstrasse 1,Transfer Nord 2023 8005 Zürich,Switzerland

[email protected]+41 78 621 87 87

Thank you.

andrea.serino@mindmaze@ch

Disclosure: Head of Neuroscience at MindMaze