Microbiology Disease Organism & Antibiotics Majesta - Test Paper-A

8/13/2019 Microbiology Disease Organism & Antibiotics Majesta - Test Paper-A

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TEST PAPER - Microbiology, Disease, Organisms &TEST PAPER - Microbiology, Disease, Organisms &AntibioticsAntibiotics

Marks Marks 8080

Time Time ! mins"! mins"

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#"$" Tick t%e rig%t anser 'Eac% carry one mark(1. Microbiology is

a) Study of plants b) Study of animals c( St)*y o+ microorganism d) All of the above.

2. Shape of a cocci will be

a( Ro)n* b) Rod shaped c) Spiral d) oma

!. ross infection in hospitals is called as

a) Secondary "nfection b) #atent "nfection c) ommunity Ac$uired "nfection *( osocomial n+ection

%. hemical substances produced by one species of organism that arecapable of

suppressing the growth or destroying the other organism are called

as

a( Antibioticsb) Antibacterialc) Antigensd) &one of the above


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'. A laboratory method of determining the susceptibility of antibiotics

is calledthe a( Sensiti.ity test"b) (iochemical testc) rease testd) Staining test

*. +hich of the following is atypical bacterium, a) Staphylococcus aureus b) Streptococcus pneumonae c( /egionella ne)mo%illa

d) -seudomonas

. Aminoglycoside antibiotics such as gentamicin /

a) Acts on the cell membrane to cause cell lea0age b( Acts on t%e 10S ribosomes to in%ibit rotein synt%esis c) Acts on the bacterial cell wall to inhibit cell wall synthesis d) Acts on &A gyrase to inhibit cell replication

. A facultative anaerobic organism is an organism3 usually abacterium

a) -seudomonas aeruginosa45ram/negative) b) &ocardia45ram/positive) c) Mycobacterium tuberculosis4acid/fast)

*( Sta%yloccoc)s, Esc%eric%ia coli, an* /isteria secies

#"2 3ill in t%e blanks 4 ' Eac% blank carry $ mark (

1. a) 5oncentration Deen*ent6illing means ,

7issue concentration or A also called as 8 6ill Ratio 7

M" acterici*alPoer

b) Time Deen*ent 6illing means ,

79 M" or M( 8 time above the M" or M( should remain

longer than %:/ ': ; of the time between two dosing internal.
http://en.wikipedia.org/wiki/Organismhttp://en.wikipedia.org/wiki/Bacteriumhttp://en.wikipedia.org/wiki/Pseudomonas_aeruginosahttp://en.wikipedia.org/wiki/Nocardiahttp://en.wikipedia.org/wiki/Gram-positivehttp://en.wikipedia.org/wiki/Mycobacterium_tuberculosishttp://en.wikipedia.org/wiki/Acid-fasthttp://en.wikipedia.org/wiki/Organismhttp://en.wikipedia.org/wiki/Bacteriumhttp://en.wikipedia.org/wiki/Pseudomonas_aeruginosahttp://en.wikipedia.org/wiki/Nocardiahttp://en.wikipedia.org/wiki/Gram-positivehttp://en.wikipedia.org/wiki/Mycobacterium_tuberculosishttp://en.wikipedia.org/wiki/Acid-fast


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Post Antibiotic ample isMycobacteri)m t)berc)losis3 the causative agent of tuberculosis

andMycobacteri)m lerae3 the causative agent of leprosy.

%. 7here are of two types resistance, ntrinsic resistance

Ac9)ire* resistance

'. 7ypes of Antibiotics , a) at)ral

b) Syntheticc) Semi-Synt%etic

*. acterial resistancemeans , A state of insensitivity or decreasedsensitivity

to drugs that ordinarily cause growth inhibition or cell death.

7. Sepsis is a serious medical condition characterised by a whole/bodyinflammatorystate caused by infection. Seticaemiais considered

a subsetof sepsis3 is a serious acute condition, rapidly progressive, life-threateninginfection.

. 7yphoid fever3 also 0nown as enteric fever3 is an illness caused bythe

bacteriumSalmonella ty%i. ommon worldwide3 it is transmittedby

ingestion of food or water contaminated with fecesfrom an infectedperson

?. eta-lactamaseis a type of en@yme produced by some bacteriathat is
http://en.wikipedia.org/wiki/Inflammationhttp://en.wikipedia.org/wiki/Infectionhttp://en.wikipedia.org/wiki/Bacteriumhttp://en.wikipedia.org/wiki/Salmonella_typhihttp://en.wikipedia.org/wiki/Salmonella_typhihttp://en.wikipedia.org/wiki/Feceshttp://en.wikipedia.org/wiki/Enzymehttp://en.wikipedia.org/wiki/Inflammationhttp://en.wikipedia.org/wiki/Infectionhttp://en.wikipedia.org/wiki/Bacteriumhttp://en.wikipedia.org/wiki/Salmonella_typhihttp://en.wikipedia.org/wiki/Feceshttp://en.wikipedia.org/wiki/Enzyme


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responsible for their resistanceto beta/lactam antibioticsli0epenicillins3

cephalosporins3 cephamycinsand carbapenems.

1:. 7he most common type of 7" is a bladder infection which is also

oftencalled cystitis. Another 0ind of 7" is a 0idney infection3 0nown asyelone%ritis3 and is much more serious.

11. 7he mechanism of action of the macrolides is by inhibition ofbacterial

Protein synthesis by binding reversibly to the subunit ':S of thebacterial

ribosome

12. Aminoglycosi*esare useful primarily in infections involvingaerobic3

negative bacterias3 such as -seudomonas3 Acinetobacter3 andpress beta/

lactamase andwould normally degrade the antibiotic.

1*. (acteria can e>change genetic information by Trans*)ction3Trans+ormationand 5on


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d) "atrogenic infection is patient induced infection due to therapeutic3diagnostic3 or investigative procedures 4 3alse ).

e) Sub/clinical infection means whose clinical signs and symptoms areclearly

visible 4 3alse).

f) Secondary infection, means a host whose resistance is lowered by a

pre/e>isting disease3 a new parasite sets up an infection 4usually

complicates the disease). 4Tr)e).

g) B lactams antibiotic inhibits the cell wall synthesis of the bacteria 4

Tr)e).

h) Meningitis is the inflammationof the protective membranescovering the

central nervous system4 Tr)e )

i) "n adults3 recently developed Aminoglycosides such as levoflo>acinand

mo>iflo>acinare often used to provide empiric coverage for patientswith

pneumonia due to S. pneumoniae 4 3alse).

C) hronic obstructive pulmonary disease 4D-)3 is a group ofdiseases

characteri@ed by limitation of airflow in the airwaythat is not fullyreversible.

4Tr)e)

#>" Matc% t%e stages o+ n+ectio)s Disease 4 '! marks(

A 1. "ncubation a. "ntroduction of microorganisms into the

tissues.
http://en.wikipedia.org/wiki/Inflammationhttp://en.wikipedia.org/wiki/Central_nervous_systemhttp://en.wikipedia.org/wiki/Levofloxacinhttp://en.wikipedia.org/wiki/Moxifloxacinhttp://en.wikipedia.org/wiki/Diseasehttp://en.wikipedia.org/wiki/Airwayhttp://en.wikipedia.org/wiki/Inflammationhttp://en.wikipedia.org/wiki/Central_nervous_systemhttp://en.wikipedia.org/wiki/Levofloxacinhttp://en.wikipedia.org/wiki/Moxifloxacinhttp://en.wikipedia.org/wiki/Diseasehttp://en.wikipedia.org/wiki/Airway


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2. linical "llness b. -eriod in which hostFs defense

mechanisms

overcome and eliminate bacteria from

the

tissues3 and the host recovers.!. -rodrome c. -eriod in which characteristic signs and

symptoms of the disease begin to be

specific

and identifiable.%. "nfection d. -hase in which non/specific signs and

symptoms of disease begin to appear.'. Resolution e.-eriod in which bacteria multiply without

causing signs or symptoms of disease.

Answers : (1- e), (2- c ), (3- d ), (4- a), (5- b )

#"?" Matc% t%e Organisms 4 '> marks(

A a) Staphylococcus. spp. 1. 5ram -ositive coccib) lostridium spp. 2. 5ram &egative coccic)


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A

a) -neumonia 1. 7emp. 9 ! D with Absolute&eutrophil

ount of 9':: Hcmmb) Acute &ecroti@ing

-ancreatitis

2. evelops due to ".I. drug users in

patients prosthetic heart valves3patient

presents with sudden heart murmurs3septic emboli.

c) Gebrile &eutropenia !. "nfectious disease of Cointsd) Sepsis %. Superficial vesiculopustular lesione)


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#"@ Matc% t%e +olloing Antibiotics it% t%eir Mo*e o+ Action

Ansers 4 '1- e (, '2- a (, '! - b (, '% - c (, '' - * (" '> - +(

JJJJJJJJJJJJJJJJJJJJJJJJJJJJJ

A (1. 5lycopeptides E (eta/lactams

a. inhibits ':S ribosomes to inhibit proteinsynthesis

2. Macrolides b. &A 5yrase E 7opoisomerase "I

!. Gluro$uinolones c. affects cell membrane permeability

%. olistin E -olymycin d. inhibits bacterial folic acid synthesis

'. o/trimo>a@ole e. inhibits cell wall synthesis

*.D>a@olidinones f. inhibits the initiation comple> formation inprotein

synthesis

Microbiology Disease Organism & Antibiotics Majesta - Test Paper-A

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