Micro Nutrient Testing - Spectracell
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SpectraCell Laboratories has become the leader in innovative clinical testing by utilizing the most advanced technology, providing the highest quality service to our physician clients, and understanding the ultimate responsibility is towards patient care.
COMPREHENSIVE
A N A L Y S I SVITAMINS
MINERALS
AMINO ACIDS
ANTIOXIDANTS
FATTY ACIDS
METABOLITES
CARBOHYDRATE METABOLISM
of those taking supplements will remain de�cient.
50%
Call 800.227.LABS (5227) or visit us online at www.SpectraCell.com
MicronutrientTesting
Uses active peripheral lymphocytes instead of serum Measures the end point of DNA synthesis Re�ects nutrient status over the last 4-8 months Measures how micronutrients and antioxidants are actually functioning within the white blood cells Re�ects total metabolic function rather than isolated biochemical pathways Demonstrates the intracellular func tion of micronutrients simultaneously Gives physicians the ability to tailor treatment plans to each patient’s speci�c requirements rather than to “norms”
Testing Lymphocytes
Provides a more accurate measurement of long term functional nutritional levels Are host to cell-mediated immune system Possesses metabolic pathways common to other cells Contains nucleus which permits rapi d DNA synthesis and cell growth Measures DNA synthesis and cell growth Are easily available in large numbers from a standard blood draw Indicates if nutrients are being absorbed and functioning properly
Clinical Applications
Knowing nutritional risk factors and treating their causes can contribute to the arrest or prevention of many degenerative conditions Patients derive signi�cant bene�ts Measuring and correcting vitamin de�ciencies are essential for patients concerned with wellness and anti-aging Micronutrient testing provides important baseline tests to identify de�ciencies
Measuring Functional Levels
Allows physicians to get more sensitive and accurate nutritional reading Provides long term status, not just an immediate snapshot Determines if the nutrient is being absorbed and functioning properly on the cellular level
Tests for B6, B12, Folate &
Homocysteine
Gives the physicians an overall informative cardiovascular program, not just a lab number Combines Micronutrient testing and HPLC methodology for Homocysteine Examines the cellular function of each individual to �nd out what is needed to �x the homocysteine problem and reduce risk, cardiovascular disease and stroke
SPECTROX® - Antioxidant Testing
Percentage gives a total antioxidant measurement, not just one or two speci�c values Measures ability of cells to withstand attack from free radicals and other oxidative stresses (antioxidant reserve) Allows for early intervention to correct de�ciencies and promote health Plays role in prevention and clinical treatment of a large variety of disease modalities
Easy Sample Collection
No refrigeration or freezing Complete test kit and transportation provided No centrifugation
Visit us at www.spectracell.com or call us at 800.227.LABS (5227) ADVANCED CLINICAL TESTING© 2009 SpectraCell Laboratories Inc. All rights reserved. DOC 305 06.09
MicronutrientTesting
Features and Bene�ts
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Nutrient Functions
Deficiency
Symptoms
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NUTRIENT POTENTIAL WHAT IT DOES WHERE IT’S FOUND SYMPTOMS AND PROBLEMS
VITAMIN EVERY
COMMON
Antioxidant, regulates oxidation reactions,stabilizes cell membrane, immune function, protects against cardiovascular disease, cataracts, macular degeneration
Wheat germ, liver, eggs, nuts, seeds, cold - pressed vegetable oils, dark leafy greens, sweet potatoes, avocados, asparagus
Skin, hair, rupturing of red blood cells, anemia, bruising, PMS, hot flashes, eczema, psoriasis, cataracts, wound healing, muscle weakness, sterility
CALCIUMVERY
COMMON
Bones, teeth, helps heart, nerves, muscles,body systems work properly, needs othernutrients to function
Dairy, wheat/soy flour, molasses, Brewer’s yeast, Brazil nuts, broccoli, cabbage, dark leafy greens, hazelnuts, oysters, sardines, canned salmon
Osteoporosis, osteomalacia, osteoarthritis, muscle cramps, irritability, acute anxiety, colon cancer risk
CHROMIUM COMMONAssists insulin function, increases fertility,carbohydrate/fat metabolism, essential for fetal growth/development
Supplementation, Brewer’s yeast, whole grains, seafood, green beans, broccoli, prunes, nuts, potatoes, meat
Metabolic syndrome, insulin resistance, decreased fertility
MAGNESIUMVERY
COMMON
300 biochemical reactions, muscle/nervefunction, heart rhythm, immune system,strong bones, regulates calcium, copper,zinc, potassium, vitamin D
Green vegetables, beans, peas, nuts, seeds, whole unprocessed grains
Appetite, nausea, vomiting, fatigue cramps, numbness, tingling, seizures, heart spasms, personality changes, heart rhythm
SELENIUM COMMON
Antioxidant, works with vitamin E, immunefunction, prostaglandin production
Brewer’s yeast, wheat germ, liver, butter, cold water fish, shellfish, garlic, whole grains, sunflower seeds, Brazil nuts
Destruction to heart/pancreas, sore muscles, fragility of red blood cells, immune system
ZINCMOST
COMMON
Supports enzymes, immune system, wound healing, taste/smell, DNA synthesis, normal growth & development during pregnancy, childhood and adolescence
Oysters, red meat, poultry, beans, nuts, seafood, whole grains, fortified breakfast cereals, dairy
Growth retardation, hair loss, diarrhea, impotence, eye & skin lesions, loss of appetite, taste, weight loss, wound healing, mental lethargy
CO Q10 COMMON
Powerful antioxidant, stops oxidation of LDL cholesterol, energy production, important to heart, liver and kidneys
Oily fish, organ meats, whole grains Congestive heart failure, high blood pressure, angina, mitral valve prolapse, fatigue, gingivitis, immune system stroke, cardiac arrhythmias
CARNITINELESS
COMMON
Energy, heart function, oxidize amino acids for energy, metabolize ketones
Red meat, dairy, fish, poultry, tempeh (fermented soybeans), wheat, asparagus, avocados, peanut butter
Elevated cholesterol, liver function, muscle weakness, reduced energy, impaired glucose control
N - ACETYL CYSTEINE (NAC)
& GLUTATHIONE
MOST COMMON
Glutathione production, lowers homocysteine, lipoprotein (a), heal lungs, inflammation, decrease muscle fatigue, liver detoxification, immune function
Meats, ricotta, cottage cheese, yogurt, wheat germ, granola, oat flakes
Free radical overload, elevated homocysteine, cancer risk, cataracts, macular degeneration, immune function, toxin elimination
ALPHA LIPOIC ACID
COMMONEnergy, blood flow to nerves, glutathione levels in brain, insulin sensitivity, effectiveness of vitamins C, E, antioxidants
Supplementation, spinach, broccoli, beef, Brewer’s yeast, some organ meats
Diabetic neuropathy, reduced muscle mass, atherosclerosis, Alzheimer’s, failure to thrive, brain atrophy, high lactic acid
COPPERLESS
COMMON
Bone formation, involved in healing process, energy production, hair and skin coloring, taste sensitivity, stimulates iron absorption, helps metabolize several fatty acids
Oysters, seeds, dark leafy vegetables,organ meats, dried legumes, whole grain breads, nuts, shellfish, chocolate, soybeans, oats, blackstrap molasses
Osteoporosis, anemia, baldness, diarrhea, general weakness, impaired respiratory function, myelopathy, decreased skin pigment, reduced resistance to infection
Nutrient Functions
Deficiency
Symptoms
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NUTRIENT POTENTIAL WHAT IT DOES WHERE IT’S FOUND SYMPTOMS AND PROBLEMS
VITAMIN B1VERY
COMMON
Carb. conversion, breaks down fats & protein, digestion, nervous system, skin, hair, eyes, mouth, liver, immune system
Pork, organ meats, whole grain and enriched cereals, brown rice, wheat germ, bran, Brewer’s yeast, blackstrap molasses
Heart, age-related cognitive decline, Alzheimer’s, fatigue
VITAMIN B2VERY
COMMON
Metabolism, carb. conversion, breaks down fats & protein, digestion, nervous system, skin, hair, eyes, mouth, liver
Brewer’s yeast, almonds, organ meats, whole grains, wheat germ, mushrooms, soy, dairy, eggs, green vegetables
Anemia, decreased free radical protection, cataracts, poor thyroid function, B6 deficiency, fatigue, elevated homocysteine
VITAMIN B3LESS
COMMON
Energy, digestion, nervous system, skin, hair, eyes, liver, eliminates toxins, sex/stress hormones, improves circulation
Beets, Brewer’s yeast, meat, poultry, organ meats, fish, seeds, nuts
Cracking, scaling skin, digestive problems, confusion, anxiety, fatigue
VITAMIN B6 COMMON
Enzyme, protein metabolism, RBC production, reduces homocysteine, nerve & muscle cells, DNA/RNA, B12 absorption, immune function
Poultry, tuna, salmon, shrimp, beef liver, lentils, soybeans, seeds, nuts, avocados, bananas, carrots, brown rice, bran, wheat germ, whole grain flour
Depression, sleep and skin problems, confusion, anxiety, fatigue
VITAMIN B12VERY
COMMON
Healthy nerve cells, DNA/RNA, red blood cell production, iron function
Fish, meat, poultry, eggs, milk, milk products
Anemia, fatigue, constipation, loss of appetite/weight, numbness and tingling in the hands and feet, depression, dementia, poor memory, oral soreness
BIOTINLESS
COMMON
Carbs, fat, amino acid metabolism (the building blocks of protein)
Salmon, meats, vegetables, grains, legumes, lentils, egg yolks, milk, sweet potatoes, seeds, nuts, wheat germ
Depression, nervous system, premature graying, hair, skin
FOLATEVERY
COMMON
Mental health, infant DNA/RNA, adolescence & pregnancy, with B12 to regulate RBC production, iron function, reduce homocysteine
Supplementation, fortified grains, tomato juice, green vegetables, black-eyed peas, lentils, beans
Anemia, immune fuction, fatigue, insomnia, hair, high homocysteine, cardiovascular disease
PANTOTHENATELESS
COMMON
RBC production, sex and stress-related hormones, immune function, healthy digestion, helps use other vitamins
Meat, vegetables, whole grains, legumes, lentils, egg yolks, milk, sweet potatoes, seeds, nuts, wheat germ, salmon
Stress tolerance, wound healing, skin problems, fatigue
VITAMIN ALESS
COMMONEyes, immune function, skin, essential cell growth and development
Milk, eggs, liver, fortified cereals, orange or green vegetables, fruits
Night blindness, immune function, zinc deficiency, fat malabsorption
VITAMIN C COMMON
Enzyme activation, second messenger roles (transmitting hormonal information), blood clotting, cell and cell organelle membrane function, nerve impulse transmission and muscular contraction, tone and irritability
Supplemention, broccoli, brussel sprouts, cantaloupe, cauliflower, citrus, guava, kiwi, papaya, parsley, peas, potatoes, peppers, parsley, rose hips, strawberries and tomatoes
Muscular and nervous irritability, muscle spasms, muscle cramps and tetany, tooth decay, periodontal disease, depression, possibly hypertension
VITAMIN DVERY
COMMONCalcium and phosphorus levels, calcium absorption, bone mineralization
Sunlight, milk, egg yolks, liver, fish Osteoporosis, calcium absorption, thyroid
VITAMIN KLESS
COMMON
Aids in the formation of clotting factors and bone proteins and the formation of glucose into glycogen for storage in the liver
Kale, green tea, turnip greens, spinach, broccoli, lettuce, cabbage, beef liver, asparagus, watercress, cheese, oats, peas, whole wheat
Excessive bleeding, a history of bruising, appearance of ruptured capillaries or menorrhagia (heavy periods)
SOURCE: DRUG-INDUCED NUTRIENT DEPLETION HANDBOOK, 2ND EDITION
Do the Prescriptions You TakeDeplete Your Nutritional Status?
ANTACIDS/ULCER MEDICATIONS Pepcid, Tagamet, Zantac, Prevacid, Prilosec, Magnesium & Aluminum antacids
ANTIBIOTICSGentomycin, neomycin,streptomycin, cephalosporins, penicillins
Vitamin B12Folic AcidVitamin DCalciumIronZinc
B VitaminsVitamin K
Tetracyclines
Dilatin, Tegretol, MysolineDepakane/Depacon
Major Tranquilizers (Thorazine, Mellaril, Prolixin, Serentil & others)
ANTI-DEPRESSANTSAdapin, Aventyl, Elavil, Pamelor,& others
ANTICONVULSANTSPhenobarbital & barbituates
CalciumMagnesiumIronVitamin B6Zinc
Coenzyme Q10Vitamin B2
Vitamin DCalciumFolic AcidBiotinCarnitineVitamin B12Vitamin B1Vitamin KCopperSeleniumZinc
Anemia, depression, tiredness, weakness, increased cardiovascular riskBirth defects, cervical dysplasia, anemia, heart disease, cancer riskOsteoporosis, muscle weakness, hearing lossOsteoporosis, heart and blood pressure irregularities, tooth decayAnemia, weakness, fatigue, hair loss, brittle nailsWeak immunity, wound healing, sense of smell/taste, sexual dysfunction
Short term depletio ects are minimal, but failure to re-inoculate theGI tract with bene cial bacteria (probiotics) often results in dysbiosis which causes gas, bloating, decreases digestion & absorption of nutrients, and also may lead to a variety of other health problems.
Osteoporosis, heart & blood pressure irregularities, tooth decayCardiovascular problems, asthma, osteoporosis, cramps, PMSSlow wound healing, fatigue, anemiaDepression, sleep disturbance, increased cardiovascular disease riskWeak immunity, wound healing, sense of smell/taste, sexual dysfunction
Various cardiovascular problems, weak immune system, low energyProblems with skin, eyes, mucous membranes and nerves
Osteoporosis, muscle weakness, hearing lossOsteoporosis, heart & blood pressure irregularities, tooth decayBirth defects, cervical dysplasia, anemia, cardiovascular diseaseHair loss, depression, cardiac irregularities, dermatitisVarious cardiovascular problems, weak immune system, low energyAnemia, depression, tiredness, weakness, increased cardiovascular riskDepression, irritability, memory loss, muscle weakness, edemaBlood coagulation, skeletal problemsAnemia, fatigue, cardiovascular and connective tissue problemsLower immunity, reduced antioxidant protectionWeak immunity, wound healing, sense of smell/taste, sexual dysfunction
DRUGNUTRIENTDEFICIENCY POTENTIAL HEALTH PROBLEM
Oral Contraceptives
FEMALE HORMONESOral Estrogen/Hormone Replacement
Folic AcidVitamin B1Vitamin B2Vitamin B3Vitamin B6Vitamin B12Vitamin CMagnesiumSeleniumZinc
Vitamin B6
Birth defects, cervical dysplasia, anemia, cardiovascular diseaseDepression, irritability, memory loss, muscle weakness, edemaProblems with skin, eyes, mucous membranes and nervesCracked, scaly skin, swollen tongue, diarrheaDepression, sleep disturbances, increased cardiovascular disease riskAnemia, depression, tiredness, weakness, increased cardiovascular riskLowered immune system, easy bruising, poor wound healingCardiovascular problems, asthma, osteoporosis, cramps, PMSLower immunity, reduced antioxidant protectionWeak immunity, wound healing, sense of smell/taste, sexual dysfunction
Depression, sleep disturbance, increased cardiovascular disease risk
ADVANCED CLINICAL TESTIN GVisit us at www.spectracell.com or call us at 800.227.5227
CHOLESTEROL DRUGSLipitor, Crestor, Zocor, and others
Coenzyme Q10 Various cardiovascular problems, weak immune system, low energy
Copyright © 2008 SpectraCell Laboratiores, Inc. All Rights Reserved. FIA 306 - 12.08
Visit us at www.spectracell.com or call us at 800.227.LABS (5227) ADVANCED CLINICAL TESTINGCopyright © 2010 SpectraCell Laboratories DOC 306 03.10
Do the Prescriptions You TakeDeplete Your Nutritional Status?
Aspirin & Salicylates
Thiazid Diuretics (HCTZ, Enduron, Diuril, Lozol, Zaroxolyn, Hygroton and others
Potassium Sparing Diuretics
Bete Blockers (Inderal, Corgard, Lopressor and others)
ACE Inhibitors (Capoten, Vasotec, Monopril & others)
DIURETICS Loop Diuretics (Lasix, Bumex, Edecrin)
CARDIOVASCULAR DRUGSAntihypertensives (Catapres, Aldomet)
Vitamin CCalciumFolic AcidIronVitamin B5
CalciumFolic AcidZinc
Coenzyme Q10
Zinc
CalciumMagnesiumVitamin B1Vitamin B6Vitamin CZincCoenzyme Q10PotassiumSodium
Coenzyme Q10Vitamin B6ZincVitamin B1
Lowered immune system, easy bruising, poor wound healingOsteoporosis, heart & blood pressure irregularities, tooth decayBirth defects, cervical dysplasia, anemia, cardiovascular diseaseAnemia, weakness, fatigue, hair loss, brittle nailsfatigue, listlessness, and possible problems with skin, liver and nerves
Osteoporosis, heart & blood pressure irregularities, tooth decayBirth defects, cervical dysplasia, anemia, cardiovascular diseaseWeak immunity, wound healing, sense of smell/taste, sexual dysfunction
Various cardiovascular problems, weak immune system, low energy
Weak immunity, wound healing, sense of smell/taste, sexual dysfunction
Osteoporosis, heart and blood pressure irregularities, tooth decayCardiovascular problems, asthma, osteoporosis, cramps, PMSDepression, irritability, memory loss, muscle weakness, edemaDepression, sleep disturbance, increased heart disease riskLowered immunity, easy bruising, poor wound healingWeak immunity, wound healing, sense of smell/taste, sexual dysfunctionVarious cardiovascular problems, weak immune system, low energyIrregular heartbeat, muscle weakness, fatigue, edemaMuscle weakness, dehydration, memory problems, loss of appetite
Various cardiovascular problems, weak immune system, low energyDepression, sleep disturbance, increased cardiovascular disease riskWeak immunity, wound healing, sense of smell/taste, sexual dysfunctionDepression, irritability, memory loss, muscle weakness, edema
DRUGNUTRIENTDEFICIENCY POTENTIAL HEALTH PROBLEM
ANTI-INFLAMMATORIESCorticosteriods: Prednisone, Medrol, Aristocort, Decodron
Folic Acid
CalciumVitamin DMagnesiumZincVitamin CVitamin B6Vitamin B12Folic AcidSeleniumChromium
Birth defects, cervical dysplasia, anemia, cardiovascular disease
Osteoporosis, heart and blood pressure irregularities, tooth decayOsteoporosis, muscle weakness, hearing lossCardiovascular problems, asthma, osteoporosis, cramps, PMSWeak immunity, wound healing, sense of smell/taste, sexual dysfunctionLowered immunity, easy bruising, poor wound healingDepression, sleep disturbances, increased cardiovascular disease riskAnemia, depression, tiredness, weakness, increased cardiovascular riskBirth defects, cervical dysplasia, anemia, cardiovascular diseaseLower immunity, reduced antioxidant protectionElevated blood sugar, cholesterol & triglycerides, diabetes risk
NSAIDS (Motrin, Aleve, Advil, Anaprox, Dolobid, Feldene, Naprosyn and others
Foscarnet CalciumMagnesiumPotassium
Osteoporosis, heart and blood pressure irregularities, tooth decayCardiovascular problems, asthma, osteoporosis, cramps, PMSIrregular heartbeat, muscle weakness, fatigue, edema
ANTIVIRAL AGENTS Zidovudine (Retrovir, AZT & other related drugs)
CarnitineCopperZincVitamin B12
Increased blood lipids, abnormal liver function and glucose controlAnemia, fatigue, cardiovascular and connective tissue problemsWeak immunity, wound healing, sense of smell/taste, sexual dysfunctionAnemia, depression, tiredness, weakness, increased cardiovascular risk
ADVANCED CLINICAL TESTIN GVisit us at www.spectracell.com or call us at 800.227.5227
Copyright © 2007 SpectraCell Laboratiores, Inc. All Rights Reserved.
Sulfonylureas (Dymelor, Tolinase,Micronase/Glynase/DiaBeta)
DIABETIC DRUGSMetformin
Coenzyme Q10
Coenzyme Q10Vitamin B12Folic Acid
Various cardiovascular problems, weak immune system, low energy
Various cardiovascular problems, weak immune system, low energy Anemia, depression, tiredness, weakness, increased cardiovascular risk Birth defects, cervical dysplasia, anemia, heart disease, cancer risk
Copyright © 2008 SpectraCell Laboratiores, Inc. All Rights Reserved. FIA 306 - 02.08
SOURCE: DRUG-INDUCED NUTRIENT DEPLETION HANDBOOK, 2ND EDITION
Visit us at www.spectracell.com or call us at 800.227.LABS (5227) ADVANCED CLINICAL TESTINGCopyright © 2010 SpectraCell Laboratories DOC 306 03.10
356.9 Hereditary and idiopathic peripheral neuropathy, unspecified
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Visit us at www.spectracell.com or call us at 800.227.5227
CODE DIAGNOSIS (SYMPTOMS, ILLNESS, INJURY OR COMPLAINT) CODE DIAGNOSIS (SYMPTOMS, ILLNESS, INJURY OR COMPLAINT)
781.0
276.2
253.0
293.0
535.00
461.1
436
288.0
477.9
995.3
704.00
314.01
088.82
353.0
490
112.85
112.9
354.0
447.4
579.0
496
780.71
245.2
472.0
346.00
414.01
255.4
269.1
311
272.9
781.1
270.4
786.09782.3259.9
401.1
401.9
345.00240.9
784.0
786.3
789.1
Abnormal involuntary movements
Acidosis
Acromegaly and gigantism
Acute delirium
Acute gastritis
Acute sinisitis, frontal
Acute, but ill-defined, cerebrovascular disease
Agranulocytosis
Allergic rhinitis, cause unspecified
Allergy, unspecified
Alopecia, unspecified
Attention deficit disorder, with hyperactivity
Babesiosis
Brachial plexus lesions
Bronchitis, not specified as acute of chronic
Candidal enteritis
Candidiasis, of unspecified site
Carpal tunnel syndrome
Celiac artery compression syndrome
Celiac disease
Chronic airway obstruction, not elsewhere classified
Chronic fatigue syndrome
Chronic lymphocytic thyroiditis
Chronic rhinitis
Classical migraine, without mention of intractable migraine
Coronary atherosclerosis, of native coronary artery
Corticoadrenal insufficiency
Deficiency of other vitamins
Depressive disorder, not elsewhere classified
Disorder of metabolism, unspecified
Disturbances of sensation of smell and taste
Disturbances of sulphur-bearing amino-acid metabolism
Dyspnea and respiratory abnormalities, other EdemaEndocrine disorder, unspecified
Essential hypertension, benign
Essential hypertension, unspecified
Generalized no convulsive epilepsyGoiter, unspecified
Headache
Hemoptysis
Hepatomegaly272.4
600.00
621.2
244.9
279.3
279.10
607.84
075
711.90
564.1
218.9
088.81
174.9
174.4
996.54
780.93
269.3
729.1
269.9
491.21
796.4
277.00
266.2
780. 79
269.8
277.89
281.1
719.44
719.48
786.52
486
272.0
753.0
786.05
780.2
786.06
985.9
785.2
266.1
269.2
Hyperlipidemia, other and unspecified
Hyperplasia of prostate (additional code required to identify urinary incontinence)
Hypertrophy of uterus
Hypothyroidism, unspecified
Immunity deficiency, unspecified
Immunodeficiency with predominant T-cell defect, unspecified
Impotence of organic origin
Infectious mononucleosis
Infective arthritis, unspecified
Irritable bowel syndrome
Leiomyoma of uterus, unspecified
Lyme disease
Malignant neoplasm, of female breast, unspecified
Malignant neoplasm of female breast, upper-outer quadrant
Mechanical complication of other specified prosthetic device, implant, and graft, due to breast prosthesis
Memory disturbance, loss or lack
Mineral deficiency, unspecified
Myalgia and myositis, unspecified
Nutritional deficiency, unspecified
Obstructive chronic bronchitis, with acute exacerbation
Abnormal clinical findings - other
Cystic Fibrosis
B-complex deficiency - other
Malaise and fatigue - other
Nutritional deficiency - other
Specified disorders of metabolism - other
Vitamin B12 deficiency anemia - other
Pain in joint, hand
Pain in joint, other specified sites
Painful respiration
Pneumonia, unspecified
Pure hypercholesterolemia
Renal agenesis and dysgenesis
Shortness of breath
Syncope and collapse
Tachypnea
Toxic effect of other metals, unspecified metal
Undiagnosed cardiac murmurs
Vitamin B6 deficiency
Vitamin deficiency, unspecified
To prevent denials, when billing third party payors, all requisitions must include all medically necessary ICD-9 diagnosis codes. ICD-9 codes are required bycertain third party payors to confirm the medical necessity of the test(s), and/or profile(s) ordered. The codes listed below are some of the most commonly received codes for testing performed at SpectraCell Laboratories. These were taken from the 2008 ICD-9 manual issued by AMA. While this list may be a useful tool, depending upon the nature of your practice, it is not complete. Please refer to the ICD-9 manual for a complete listing. The ultimate responsibility for correct coding lies with the ordering physician. Please place all medically appropriate ICD-9 codes on the requisition. If ordering for screening purposes, please provide the appropriate screening ICD-9 codes.
Diagnosis Codes
250 Diabetes mellitus250.0 Diabetes without complications250.0 O type II or unspecified type, not stated as uncontrolled250.1 1 type I (juvenile type), not stated as uncontrolled250.2 2 type II or unspecified type, uncontrolled250.3 3 type I (juvenile type), uncontrolled250.00 Diabetes mellitus without mention of complication250.10 Diabetes with ketocidosis250.20 Diabetes with hyperosmolarity250.30 Diabetes with other coma250.40 Diabetes with renal manifestations250.50 Diabetes with ophthalmic manifestations250.60 Diabetes with neurological manifestations250.70 Diabetes with peripheral circulatory disorders250.80 Diabetes with other specified manifestations250.90 Diabetes with unspecified complication
ADVANCED CLINICAL TESTING
AddressURL
Phone/FaxNo Appointment, Doctor's Note or Insurance Necessary
Are you spending a fortune on all of these?
You may not have to.
FIND OUT
TODAY
WITH THE
MICRONUTRIENT
TEST.
AVAILABLE AT
SPECTRACELL LABORATORIES
ADVANCED CLINICAL TESTING
Product Tools
Ocular Health - Good eyesight and prevention of cataracts and macular degeneration
require adequate levels of Vitamin E and Vitamin A.
Cardiovascular Support - Vitamin B2, Vitamin B6, Vitamin B12 and Folic Acid are all required for reducing homocysteine levels in the blood and protecting arteries and nerve fibers.
Heart Health - Nutrients that protect the cardiovascular system include Vitamin B6, Vitamin B12, Folic Acid, Vitamin E, CoQ10, Calcium,
Magnesium and Carnitine.
Bone Health - Vitamin D, Vitamin B6, Vitamin B12, Folic Acid,
Calcium, Magnesium and Zinc are all nutrients that assist in bone remodeling, to ward off osteoporosis and other diseases that weaken the skeletal system.
Liver Health - Cysteine and N-Acetyle Cysteine, Selenium, Vitamin B2 and Vitamin B3 enhance liver function and optimize levels of glutathione which helps cells fight off toxic challenges.
Joint Support - Vitamin E, Alpha-Lipoic Acid and
B Vitamins all contribute to joint support and controlling inflammation.
Antioxidant Status -Measures the nutrients that help prevent or repair cellular damage
caused by oxidation.
SPECTROX® measures the total antioxidant function of cells by measuring their ability to withstand oxidative stress.
MicroNutrient Testingis available now exclusively from SpectraCell Laboratories. This patented analysis measures levels of selected vitamins, minerals, antioxidants and other essential micronutrients within your white blood cells.www.SpectraCell.com
Metabolic Health - Vitamin B3, Vitamin B6, Vitamin B12 Vitamin E, Biotin, CoQ10, Chromium, Magnesium and Zinc all help the body handle daily sugar load, keeping systems responsive to insulin
and restoring lost insulin sensitivity.
50% of people at risk for HEART DISEASE are not identified by routine testing.50%
Standard Cholesterol Testingis NOT ENOUGH.
ADVANCED TESTING FOR CARDIOVASCULAR RISK
800.227.LABS (5227)www.SpectraCell .com
Visit SpectraCell Laboratories to learn about the Lipoprotein Particle ProfileTM to assess cardiovascular risk.
of those taking multivitaminsARE STILL DEFICIENT
50%50%Research has shown that
If only an apple a day
was really enough.
Ask your doctor today about a simple comprehensive blood test to analyze vitamins, minerals and nutrients vital to your well being.
800.227.LABS (5227) www.SpectraCell.com
NUTRIENT POTENTIAL WHAT IT DOES WHERE IT’S FOUND SYMPTOMS AND PROBLEMS
VITAMIN E VERY
COMMON
Antioxidant, regulates oxidation reactions, stabilizes cell membrane, immune function, protects against cardiovascular disease, cataracts, macular degeneration
Wheat germ, liver, eggs, nuts, seeds, cold-pressed vegetable oils, dark leafy greens, sweet potatoes, avocados, asparagus
Skin, hair, rupturing of red blood cells, anemia, bruising, PMS, hot flashes, eczema, psoriasis, cataracts, wound healing, muscle weakness, sterility
CALCIUM VERY
COMMON
Bones, teeth, helps heart, nerves, muscles, body systems work properly, needs other nutrients to function
Dairy, wheat/soy flour, molasses, Brewer's yeast, Brazil nuts, broccoli, cabbage, dark leafy greens, hazelnuts, oysters, sardines, canned salmon
Osteoporosis, osteomalacia, osteoarthritis, muscle cramps, irritability, acute anxiety, colon cancer risk
CHROMIUM COMMON Assists insulin function, increased fertility, carbohydrate/fat metabolism, essential for fetal growth/development
Supplementation, Brewer’s yeast, whole grains, seafood, green beans, broccoli, prunes, nuts, potatoes, meat
Metabolic syndrome, insulin resistance, decreased fertility
MAGNESIUM VERY
COMMON
300 biochemical reactions, muscle/nerve function, heart rhythm, immune system, strong bones, regulates calcium, copper, zinc, potassium, vitamin D
Green vegetables, beans, peas, nuts, seeds, whole unprocessed grains
Appetite, nausea, vomiting, fatigue cramps,, numbness, tingling, seizures, heart spasms, personality changes, heart rhythm
SELENIUM COMMON Antioxidant, works with vitamin E, immune function, prostaglandin production
Brewer's yeast, wheat germ, liver, butter, cold water fish, shellfish, garlic, whole grains, sunflower seeds, Brazil nuts
Destruction to heart/pancreas, sore muscles, fragility of red blood cells, immune system
ZINC MOST
COMMON
Supports enzymes, immune system, wound healing, taste/smell, DNA synthesis, normal growth & development during pregnancy, childhood, adolescence
Oysters, red meat, poultry, beans, nuts, seafood, whole grains, fortified breakfast cereals, dairy
Growth retardation, hair loss, diarrhea, impotence, eye & skin lesions, loss of appetite, taste, weight loss, wound healing, mental lethargy
COQ10 COMMON Powerful antioxidant, stops oxidation of LDL cholesterol, energy production, important to heart, liver and kidneys
Oily fish, organ meats, whole grains
Congestive heart failure, high blood pressure, angina, mitral valve prolapse, fatigue, gingivitis, immune system stroke, cardiac arrhythmias
CARNITINE LESS
COMMON Energy, heart function, oxidize amino acids for energy, metabolize ketones
Red meat, dairy, fish, poultry, tempeh (fermented soybeans), wheat, asparagus, avocados, peanut butter
Elevated cholesterol, liver function, muscle weakness, reduced energy, impaired glucose control
N-ACETYL CYSTEINE (NAC)
& GLUTATHIONE
MOST COMMON
Glutathione production, lowers homocysteine, lipoprotein(a), heal lungs, inflammation, decrease muscle fatigue, liver detoxification, immune function
Meats, ricotta, cottage cheese, yogurt, wheat germ, granola, oat flakes
Free radical overload, elevated homocysteine, cancer risk, cataracts, macular degeneration, immune function, toxin elimination
ALPHA LIPOIC ACID
COMMON Energy, blood flow to nerves, glutathione levels in brain, insulin sensitivity, effectiveness of vitamins C, E, antioxidants
Supplementation, spinach, broccoli, beef, Brewer's yeast, some organ meats
Diabetic neuropathy, reduced muscle mass, atherosclerosis, Alzheimer’s, failure to thrive, brain atrophy, high lactic acid
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SOURCE: DRUG-INDUCED NUTRIENT DEPLETION HANDBOOK, 2ND EDITION
Do the Prescriptions You TakeDeplete Your Nutritional Status?
ANTACIDS/ULCER MEDICATIONS Pepcid, Tagamet, Zantac, Prevacid, Prilosec, Magnesium & Aluminum antacids
ANTIBIOTICSGentomycin, neomycin,streptomycin, cephalosporins, penicillins
Vitamin B12
Folic Acid
Vitamin D
Calcium
Iron
Zinc
B Vitamins
Vitamin K
Tetracyclines
Dilatin, Tegretol, Mysoline
Depakane/Depacon
Major Tranquilizers (Thorazine, Mellaril, Prolixin, Serentil & others)
ANTI-DEPRESSANTSAdapin, Aventyl, Elavil, Pamelor,& others
ANTICONVULSANTSPhenobarbital & barbituates
Calcium
Magnesium
Iron
Vitamin B6
Zinc
Coenzyme Q10
Vitamin B2
Vitamin D
Calcium
Folic Acid
Biotin
Carnitine
Vitamin B12
Vitamin B1
Vitamin K
Copper
Selenium
Zinc
Anemia, depression, tiredness, weakness, increased cardiovascular risk
Birth defects, cervical dysplasia, anemia, heart disease, cancer risk
Osteoporosis, muscle weakness, hearing loss
Osteoporosis, heart and blood pressure irregularities, tooth decay
Anemia, weakness, fatigue, hair loss, brittle nails
Weak immunity, wound healing, sense of smell/taste, sexual dysfunction
Short term depletion affects are minimal, but failure to re-inoculate the
GI tract with beneficial bacteria (probiotics) often results in dysbiosis which
causes gas, bloating, decreases digestion & absorption of nutrients, and also
may lead to a variety of other health problems.
Osteoporosis, heart & blood pressure irregularities, tooth decay
Cardiovascular problems, asthma, osteoporosis, cramps, PMS
Slow wound healing, fatigue, anemia
Depression, sleep disturbance, increased cardiovascular disease risk
Weak immunity, wound healing, sense of smell/taste, sexual dysfunction
Various cardiovascular problems, weak immune system, low energy
Problems with skin, eyes, mucous membranes and nerves
Osteoporosis, muscle weakness, hearing loss
Osteoporosis, heart & blood pressure irregularities, tooth decay
Birth defects, cervical dysplasia, anemia, cardiovascular disease
Hair loss, depression, cardiac irregularities, dermatitis
Various cardiovascular problems, weak immune system, low energy
Anemia, depression, tiredness, weakness, increased cardiovascular risk
Depression, irritability, memory loss, muscle weakness, edema
Blood coagulation, skeletal problems
Anemia, fatigue, cardiovascular and connective tissue problems
Lower immunity, reduced antioxidant protection
Weak immunity, wound healing, sense of smell/taste, sexual dysfunction
DRUGNUTRIENTDEFICIENCY POTENTIAL HEALTH PROBLEM
Oral Contraceptives
FEMALE HORMONESEstrogen/Hormone Replacement
Folic Acid
Vitamin B1
Vitamin B2
Vitamin B3
Vitamin B6
Vitamin B12
Vitamin C
Magnesium
Selenium
Zinc
Vitamin B6
Birth defects, cervical dysplasia, anemia, cardiovascular disease
Depression, irritability, memory loss, muscle weakness, edema
Problems with skin, eyes, mucous membranes and nerves
Cracked, scaly skin, swollen tongue, diarrhea
Depression, sleep disturbances, increased cardiovascular disease risk
Anemia, depression, tiredness, weakness, increased cardiovascular risk
Lowered immune system, easy bruising, poor wound healing
Cardiovascular problems, asthma, osteoporosis, cramps, PMS
Lower immunity, reduced antioxidant protection
Weak immunity, wound healing, sense of smell/taste, sexual dysfunction
Depression, sleep disturbance, increased cardiovascular disease risk
ADVANCED CLINICAL TESTINGVisit us at www.spectracell.com or call us at 800.227.5227
CHOLESTEROL DRUGSLipitor, Crestor, Zocor, and others
Coenzyme Q10 Various cardiovascular problems, weak immune system, low energy
Copyright © 2008 SpectraCell Laboratiores, Inc. All Rights Reserved. FIA 306 - 12.08
Visit us at www.spectracell.com or call us at 800.227.LABS (5227) ADVANCED CLINICAL TESTINGCopyright © 2009 SpectraCell Laboratories DOC 306-01.09
Take ActionSpectraCell’s FIA™ picks up nutritional deficiencies that routine testing does not. If you are pre-diabetic or already have diabetes, functional testing from SpectraCell is right for you, so act now. Ask your doctor about SpectraCell’s FIA™ tests to find out if you are deficient in any nutrients presented in this brochure and take action to prevent and fight diabetes.
Your NutritionalStatus Matters10401 Town Park Drive Houston, Texas 77072
For more information call 800.227.LABS (5227)or visit us online at www.SpectraCell.com ADVANCED CLINICAL TESTING
a ea e ctct ooUnderstanding DiabetesAccording to the American DiabetesAssociation, type 2 diabetes is the mostcommon form of diabetes. With this typeof diabetes, cells do not receive enoughinsulin. As a result, cells starve for energy, and over time, a glucose buildup in the blood stream causes negative effects on a person’s eyes, kidneys, nerves or heart.
Today’s fast-paced society has led to quicker, higher carbohydrate alternatives as food sources. As a result, there is a greater threat of developing diabetes due to cells becoming insulin-resistant.
Micronutrients such as niacin, magnesium, calcium, zinc, carnitine, inositol, alpha-lipoic acid, as well as vitamins E, B6 and D all play an important role in the prevention and treatment of diabetes.
Ask your doctor today about SpectraCell’s FIA™ tests to accurately diagnose your body’s exact needs and/or deficiencies. Though diabetes is a serious disease - with the right treatment - living a longer, healthier life can be made easier.
20.8 million people in the United States, or 7% of the population, have diabetes.An estimated 14.6 million have been diagnosed.6.2 million people (or nearly one-third) are unaware that they already have the disease.41 million people in the United States, ages 40 to 74, have pre-diabetes. 10.9 million, or 10.5% of all men aged 20 years or older, have diabetes although nearly one-third of them do not know it.9.7 million, or 8.8% of all women aged 20 years or older, have diabetes although nearlyone-third of them do not know it.The prevalence of diabetes is at least 2 to 4 times higher among non-Hispanic Black, Hispanic/Latino American, American Indian, and Asian Pacific Islander women than amongnon-Hispanic white women.
Did You Know...
A C L O S E R L O O K A T
Balancing your nutritional status has never been easier.
Ask your doctor about MicroNutrient Testing!
Does your body
need all of these?
Find out today with the
MicroNutrient Test available at
AddressURL
Phone/Fax
No Appointment, Doctor's Note or Insurance Necessary
ARE YOU WELLBALANCED?BALANCED?
FIND OUT TODAY IF YOU’RE GETTING THE VITAMINS & MINERALS THAT
YOUR BODY NEEDS.
E X E C U T I V E H E A L T H
A N DW E L L N E S S
E X E C U T I V E H E A L T H
A N DW E L L N E S S
Does your nutritional balance stack up?FIND OUT TODAY IF YOU’RE GETTING
THE VITAMINS & MINERALS THAT
YOUR BODY NEEDS.
www.SpectraCell.com
Want to feel young again? WE CAN HELP!
www.BeyondWellnesscc.com
The LPP Advantage
Copyright © 2008 SpectraCell Laboratories DOC 412-12.08ADVANCED CLINICAL TESTING
Visit us at www.spectracell.com or call us at 800.227.LABS (5227)
Cholesterol has historically been used as the standard indicator for cardiovascular disease, being classified as HDL (good) or LDL (bad). However, it is actually the lipoprotein particles that carry the cholesterol throughout the body, not the cholesterol within them, that are responsible for key steps in plaque production and the resulting development of cardiovascular disease.
Why is it important to know lipoprotein numbers?Cardiovascular risk increases with a higher number of low density lipoprotein (LDL) particles, regardless of how much cholesterol each lipoprotein particle contains. This is because both a higher number of LDL particles or smaller sized LDL particles dramatically increase the probability of lipoproteins penetrating the arterial wall, where it can cause serious damage.
Why measure lipoprotein subgroups?Measuring the lipoprotein subgroups is the only way to evaluate new risk factors, which is crucial for accurate assessment of cardiovascular risk and treatment, according to the National Cholesterol Education Program (NCEP).
Over 20% of the population has cholesterol-depleted LDL. This is a condition in which a patient’s cholesterol may be “normal,” but their lipoprotein particle number and hence their actual risk would be much higher than conventional cholesterol tests would indicate. This is especially common in persons whose triglycerides are high or HDL is low. In a cholesterol-depleted patient, there can be up to a 40 percent error in risk assessment in a standard lipid panel.
Use LPPTM in your practice for accurate cardiovascular risk assessment. With LPPTM, a physician can begin to treat patients with atherogenic lipoprotein profiles before overt dyslipidemia becomes apparent.
NCEP Emerging Risk Factors � Small, dense LDL – these atherogenic particles easily penetrate the arterial endothelium causing plaque.
� RLP (Remnant Lipoprotein) – very atherogenic lipoprotein that doesn’t need to be oxidized to form plaque.
� Lp(a) – a prothrombotic small, dense LDL
� HDL2b – positively correlates with heart health because it is an indicator of how well excess lipids are removed.
Approximately 50 percent of people suffering from heart attacks have shown “normal” cholesterol numbers. NIH – National Heart, Blood and Lung Institute, 2001
Only measuring cholesterol can be misleading.
Copyright © SpectraCell Laboratories 2008 All Rights Reserved
PLAQUE RUPTURES DUE TO INFLAMMATION
Lp(a) RLP HDL2b
HDL3
Foam Cells Build Plaque
Foam Cell
LDL
DENSE LDL
OXIDIZED LDL
MACROPHAGE CELL
ARTERIAL INTIMA
ARTERIAL LUMEN MONOCYTE CELL
DAMAGED
CELL
ENDOTHELIUM
SpectraCell’s Lipoprotein Particle Profile™ (LPP™) identifies all the National
Cholesterol Education Program’s (NCEP) Lipoprotein Risk Factors.
DOC 416 LPP™ 12.08
ADVANCED TESTING FOR CARDIOVASCULAR RISK
Visit us at www.spectracell.com or call us at 800.227.LABS (5227)
ADVANCED CLINICAL TESTING
are small dense LDL’s and easily oxidized. Lp(a) is prothrombotic in many of the genetic variations.
50%of people at risk for
HEART DISEASE
are not identified
by routine testing.50%Standard Cholesterol Testing
is NOT ENOUGH.
ADVANCED TESTING FOR CARDIOVASCULAR RISK
800.227.LABS (5227)
www.SpectraCell .com
Ask your doctor about the LPPTM test today.
Standard Cholesterol Testing
is NOT ENOUGH.
SPECTRACELL LABORATORIES
ADVANCED CLINICAL TESTING
25%of patients on aspirin therapy
receive little or no benefit.
If you… take a cholesterol lowering drug...
you test your cholesterol.
take blood pressure medication...
you test your blood pressure.
take aspirin to prevent a heart attack...
NOW you can test your
Aspirin Effect!
Did you know?
People who do not respond to aspirin
are three times more likely to die of
cardiovascular disease than those
who respond well to aspirin.
Nearly 2,400 people die of cardiovascular
disease EACH DAY in the United States.
An estimated 1.1 million Americans
will have a new or recurrent heart
attack this year.
40% of these heart attacks will be fatal.
Studies show that the correct dose of
aspirin helps to significantly reduce
thromboxane levels.
Are you taking aspirin
to prevent a heart attack?
Is it working?
Copyright © 2008 SpectraCell Laboratories - DOC 505 (12.08)
10401 Town Park Drive Houston, Texas 77072 800.227.LABS (5227) www.SpectraCell.com
Aspirin Response Test - laboratory test for urinary 11dhTxB2
Pathways of Thromboxane Production
Check for Concomitant Ibuprofen or NSAID usage—this can inhibit effect of aspirin
Modify Aspirin Dose
Check for Elevated Cholesterol- this can alter aspirin’s effect
Consider underlying condition i.e. Pre-Diabetes/Diabetes
Lower and Control Cholesterol
Retest
If results remain > 1500 with no aspirin effect consider changing dose; additional and/or
alternative anti-platelet therapy
≤ 1500 pg/mg
Aspirin Effect
> 1500 pg/mg
No Aspirin Effect
Aspirin
Ingested
Ensure
Compliance
Step 1
Step 2
Step 3
Step 4
COX-2 COX-1
Inflammation Low-dose
aspirin
Points toconsider when interpreting results.
10401 Town Park Drive Houston, Texas 77072 800.227.LABS (5227) www.SpectraCell.com
Copyright © 2008 SpectraCell Laboratories. All Rights Reserved DOC 507 (08.08)
Visit us at www.spectracell.com or call us at 800.227.LABS (5227)
Q. Why do I need the Aspirin Response Test ?A. Medical studies indicate that not everyone benefits equally from low dose aspirin. In fact some
people have been reported to be aspirin “resistant” but increasing studies indicate that it may be
a question of aspirin therapy “failure”. Because aspirin is known to reduce the risk of heart attack
and stroke by helping stop platelets from sticking together, the Aspirin Response Test allows the
doctor to determine if you are benefiting optimally from your aspirin regimen.Q. What are the chances that my platelets are not responding to aspirin?
A. According to reports in the medical literature, 10% to 40% of patients taking aspirin were not
receiving the desired result. The fact is that even if aspirin is working on your platelets, there are
other factors that may overcome the benefit of the aspirin. Traditional platelet function assays can
not detect this result.Q. What are the dangers to me if I am not benefiting from my aspirin?
A. Outcome studies have demostrated that patients with a poor response to aspirin therapy have
a higher incidence of second heart attacks, strokes or even death when compared to patients with
a good response. Q. Why shouldn’t I just take more aspirin?A. Increasing the amount of aspirin you take may cause an increase in unwanted side effects such as
stomach discomfort or gastrointestinal bleeding. More importantly, the aspirin may be doing its job
but there is some other factor overcoming its benefit which may require an additional medication.
Only your physician should decide if it is safe to change your aspirin dosage.Q. How often should I be tested?A. The optimum frequency of testing has not been established. Clinical studies indicate that certain
individuals lose the benefit of aspirin therapy over time due to atherosclerotic disease or
increases in cholesterol. Q. What does the Aspirin Response Test measure?A. When an individual’s platelets become activated they release a chemical called Thromboxane A2
(TxA2) which causes more platelets to become activated and stick together. This may
cause formation of a blood clot. The ART test measures a metabolite of TxA2 called
11-dehydro thromboxane B2 which is excreted in the urine. When an individual is benefiting
from their aspirin therapy the level of 11-dehydroTxB2 in the urine is very low.Q. Is the Aspirin Response Test complicated?A. No. This test is performed on a random urine sample. It is important that you be able to give your
doctor a thorough history of the other drugs you have taken during the past 10 days, especially
other non-steroidal anti-inflammatory drugs. Be sure to mention any dietary supplements and
alcohol intake. Note the amount and frequency of aspirin usage.
Copyright © 2008 SpectraCell Laboratories. All Rights Reserved DOC 506 (08.08)
Visit us at www.spectracell.com or call us at 800.227.LABS (5227)
Q. Do all NSAID’s interfere with aspirin binding?
A. To date, only Ibuprofen has been proven to interfere with the binding of aspirin to the
platelet which prevents acetylation of the COX-1 enzyme.
Q. How soon after taking NSAID’s is it safe to take aspirin for heart benefit?
A. Again this has been addressed only in regard to Ibuprofen. It is presently recommended that
the individual must wait at least 8 hours after ingesting Ibuprofen before ingesting aspirin or at
least 30 minutes after aspirin ingestion before ingesting Ibuprofen.
Q. How long should I wait after a patient has begun aspirin therapy to test?
A. According to the literature, it takes up to 5 days for low-dose aspirin therapy to achieve
maximum reduction in urinary 11-dehydro thromboxane B2 levels.
Q. Does liver disease affect the results?
A. Yes. Liver disease may prevent the metabolism of thromboxane A2 to
11-dehydro thromboxane B2.
Q. Does renal disease affect the results?
A. Yes. Kidney disease may prevent the metabolism of thromboxane A2 to
11-dehydro thromboxane B2.
Q. Does the platelet count of the patient have an effect on the test?
A. To date no studies have been performed addressing a relationship between platelet count
and levels of 11-dehydro thromboxane B2. If there is sufficient aspirin on board to block the
COX-1 pathway, then the individual is benefiting. Platelet count does not necessarily reflect
functional platelets, therefore a correlation can not be assumed. More importantly, if the
individual does not have a high percentage of platelet turnover, a daily regimen of aspirin
should eventually knock out all of the platelets because the effect of aspirin on the platelet is
irreversible and lasts for the lifetime of the platelet.
Q. How much aspirin should I be recommending and what about adding Plavix?
A. Within the guidelines for treatment with aspirin, the physician may administer doses from 81
to 325 mg. It is completely up to the physician to recommend any change in aspirin dose based
on the individual’s circumstances. Adding Plavix to a patient’s anti-platelet regimen is strictly
up to the physician and depends on the clinical condition of the patient. Certain studies have
demonstrated an added benefit with Plavix in addition to aspirin in symptomatic patients;
however, asymptomatic patients have not always demonstrated an added benefit.
SPECTRACELL LABORATORIES ADVANCED CLINICAL TESTING
327 309 335 306303
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9
781.0
276.2
253.0
293.0
535.00
461.1
436
288.0
477.9
995.3
704.00
314.01
088.82
353.0
490
112.85
112.9
354.0
447.4
579.0
496
780.71
245.2
472.0
346.00
414.01255.4
269.1
311
272.9
781.1
270.4
786.09782.3259.9
401.1
401.9
345.00240.9
784.0
786.3
789.1
Abnormal involuntary movements
Acidosis
Acromegaly and gigantism
Acute delirium
Acute gastritis
Acute sinisitis, frontal
Acute, but ill-defined, cerebrovascular disease
Agranulocytosis
Allergic rhinitis, cause unspecified
Allergy, unspecified
Alopecia, unspecified
Attention deficit disorder, with hyperactivity
Babesiosis
Brachial plexus lesions
Bronchitis, not specified as acute of chronic
Candidal enteritis
Candidiasis, of unspecified site
Carpal tunnel syndrome
Celiac artery compression syndrome
Celiac disease
Chronic airway obstruction, not elsewhere classified
Chronic fatigue syndrome
Chronic lymphocytic thyroiditis
Chronic rhinitis
Classical migraine, without mention of intractable migraine
Coronary atherosclerosis, of native coronary artery Corticoadrenal insufficiency
Deficiency of other vitamins
Depressive disorder, not elsewhere classified
Disorder of metabolism, unspecified
Disturbances of sensation of smell and taste
Disturbances of sulphur-bearing amino-acid metabolism
Dyspnea and respiratory abnormalities, other EdemaEndocrine disorder, unspecified
Essential hypertension, benign
Essential hypertension, unspecified
Generalized no convulsive epilepsyGoiter, unspecified
Headache
Hemoptysis
Hepatomegaly272.4
600.00
621.2
244.9
279.3
279.10
607.84
075
711.90
564.1
218.9
088.81
174.9
174.4
996.54
780.93
269.3
729.1
269.9
491.21
796.4
277.00
266.2
780. 79
269.8
277.89
281.1
719.44
719.48
786.52
486
272.0
753.0
786.05
780.2
786.06
985.9
785.2
266.1
269.2
Hyperlipidemia, other and unspecified
Hyperplasia of prostate (additional code required to identify urinary incontinence)
Hypertrophy of uterus
Hypothyroidism, unspecified
Immunity deficiency, unspecified
Immunodeficiency with predominant T-cell defect, unspecified
Impotence of organic origin
Infectious mononucleosis
Infective arthritis, unspecified
Irritable bowel syndrome
Leiomyoma of uterus, unspecified
Lyme disease
Malignant neoplasm, of female breast, unspecified
Malignant neoplasm of female breast, upper-outer quadrant
Mechanical complication of other specified prosthetic device, implant, and graft, due to breast prosthesis
Memory disturbance, loss or lack
Mineral deficiency, unspecified
Myalgia and myositis, unspecified
Nutritional deficiency, unspecified
Obstructive chronic bronchitis, with acute exacerbation
Abnormal clinical findings - other
Cystic Fibrosis
B-complex deficiency - other
Malaise and fatigue - other
Nutritional deficiency - other
Specified disorders of metabolism - other
Vitamin B12 deficiency anemia - other
Pain in joint, hand
Pain in joint, other specified sites
Painful respiration
Pneumonia, unspecified
Pure hypercholesterolemia
Renal agenesis and dysgenesis
Shortness of breath
Syncope and collapse
Tachypnea
Toxic effect of other metals, unspecified metal
Undiagnosed cardiac murmurs
Vitamin B6 deficiency
Vitamin deficiency, unspecified
Diagnosis Codes
CODE DIAGNOSIS (SYMPTOMS, ILLNESS, INJURY OR COMPLAINT) CODE DIAGNOSIS (SYMPTOMS, ILLNESS, INJURY OR COMPLAINT)
To prevent denials when billing third party payors, all requisitions must include all medically necessary ICD-9 diagnosis codes. ICD-9 codes are required bycertain third party payors to confirm the medical necessity of the test(s), and/or profile(s) ordered. The codes listed below are some of the most commonly received codes for testing performed at SpectraCell Laboratories. These were taken from the 2008 ICD-9 manual issued by AMA. While this list may be a useful tool, depending upon the nature of your practice, it is not complete. Please refer to the ICD-9 manual for a complete listing. The ultimate responsibility for correct coding lies with the ordering physician. Please place all medically appropriate ICD-9 codes on the requisition. If ordering for screening purposes, please provide the appropriate screening ICD-9 codes.
250 Diabetes mellitus250.0 Diabetes without complications250.0 O type II or unspecified type, not stated as uncontrolled250.1 1 type I (juvenile type), not stated as uncontrolled250.2 2 type II or unspecified type, uncontrolled250.3 3 type I (juvenile type), uncontrolled250.00 Diabetes mellitus without mention of complication250.10 Diabetes with ketocidosis250.20 Diabetes with hyperosmolarity250.30 Diabetes with other coma250.40 Diabetes with renal manifestations250.50 Diabetes with ophthalmic manifestations250.60 Diabetes with neurological manifestations250.70 Diabetes with peripheral circulatory disorders250.80 Diabetes with other specified manifestations250.90 Diabetes with unspecified complication
Visit us at www.spectracell.com or call us at 800.227.LABS (5227) ADVANCED CLINICAL TESTING
302
331
402 408 412 403
V I D E O S
DR. WILDER
LOOP VIDEO
PATIENT HANDOUT PHYSICIAN HANDOUT PATIENT FAQs PHYSICIAN FAQs
PILLS IN HAND
3 PEOPLE W/ VEGGIESJUMP YOUNG
BALANCE
STACKED APPLE
BROCHURES ARE ALSO
AVAILABLE IN SPANISH
BROCHURES ARE ALSO AVAILABLE IN SPANISH
Mark Houston, M.D. M.S., SCH, ABAAM, FACP, FAHA Internal Medicine Hypertension Institute – A Cardiovascular Center of Excellence St. Thomas Medical Center Nashville, TN "SpectraCell offers a unique, scientifically-based nutrient evaluation of specific deficiencies that allows targeted treatment with nutritional supplements. The detection of these abnormalities allows for a biological, functional and nutritional biochemistry approach for the prevention and treatment of many diseases for which the basic problem originated with the missing nutrient and subsequent downstream nutritional dysfunction and illness. Patient and physician recognition of this valid testing will improve patient compliance, allow for tailored therapy and reduce numerous diseases” Seth Baum, M.D. Cardiologist VitalRemedy MD Boca Raton, FL “As an interventional cardiologist and electrophysiologist dedicated to the advancement of cardiovascular health, I have come to appreciate the need for individualizing our approach to patient care. Though it’s important to use large clinical trials as a means of guiding us in an “evidence based” manner, it has become clear to most of us that these trials too often fall short in their clinical utility. They frequently fail to address the needs of individual patients, unique and extraordinarily complex beings who’ve entrusted their health and well being to us, their doctors. A question often raised by patients and physicians alike relates to the use of antioxidant supplements such as vitamins C and E, Co Q10, and alpha lipoic acid. Trials evaluating antioxidants have been mixed, spanning the gamut from very positive to equally negative. Most of these trials, however, have been neutral. The failure of these studies to solve the antioxidant puzzle relates to their reliance upon fixed dose supplementation; they neglect the wide range of individual responses that occur when using antioxidants. They have also ignored the issue of balancing antioxidants. As antioxidants exist in vivo within a constantly recirculating and regenerating network, they must be consumed in balance so that an excess of one does not adversely affect the remaining “players” in what ought to be a harmonious system. In order to help my patients navigate the tumultuous seas of antioxidant supplementation, I have relied upon the Spectrox® blood test for the better part of the last decade. By utilizing this test, I have the ability to supplement patients on an individual, and an “as need” basis. Spectrox® eliminates the guesswork from supplementation, and permits not only my patients, but me as well, to feel comfortable that we are “doing the right thing.” Follow up blood tests enable us to document that any changes we’ve made have had their desired affect. If they haven’t, then it’s back to the drawing board for another attempt. “
Visit us at www.spectracell.com or call us at 800.227.LABS (5227) ADVANCED CLINICAL TESTING
Copyright © 2009 SpectraCell Laboratories DOC 310-01.09
Client Testimonials
Rita Ellithorpe, M.D. Internal Medicine Tustin Longevity Center “SpectraCell’s MicroNutrient Testing is a truly valuable diagnostic tool for my practice.” Michael O'Neal, D.O. Internal Medicine Primary Care Team Physician Toronto Blue Jays Major League Baseball Club Chief Executive Officer CooperativeMed "SpectraCell’s MicroNutrient Testing allows me to diagnose specific functional deficienciesand subsequently compound supplements appropriate for the individual needs of my patients."
Diana Schwarzbein, M.D. Endocrinologist Endocrinology Institute of Santa Barbara Santa Barbara, CA “There are many supplements from vitamins to orthomolecular molecules that can influence a person's metabolism. As we all know, multiple supplements can be as overwhelming as prescription drugs and just as costly. Will I recommend zinc, lipoic acid and Co Q-10 to help a patient recover from adrenal gland burn out, or does the individual make enough lipoic acid and I need to only recommend zinc and CoQ10? I use the information from SpectraCell’sMicroNutrient Testing to determine which of these would be the first line choices for that particular patient and their current situation.
I have found that when my patients are shown their particular data from this blood test, it motivates them to take their supplements consistently and I am able to put together a supplement and dietary regimen that targets my patient’s unique deficiencies. Objective data is always helpful.”
Visit us at www.spectracell.com or call us at 800.227.LABS (5227) ADVANCED CLINICAL TESTING
Copyright © 2009 SpectraCell Laboratories DOC 310-01.09
Client Testimonials
Ocular Health - Good eyesight and prevention of cataracts and macular degeneration
require adequate levels of Vitamin E and Vitamin A.
Cardiovascular Support - Vitamin B2, Vitamin B6, Vitamin B12 and Folic Acid are all required for reducing homocysteine levels in the blood and protecting arteries and nerve fibers.
Heart Health - Nutrients that protect the cardiovascular system include Vitamin B6, Vitamin B12, Folic Acid, Vitamin E, CoQ10, Calcium,
Magnesium and Carnitine.
Bone Health - Vitamin D, Vitamin B6, Vitamin B12, Folic Acid,
Calcium, Magnesium and Zinc are all nutrients that assist in bone remodeling, to ward off osteoporosis and other diseases that weaken the skeletal system.
Liver Health - Cysteine and N-Acetyle Cysteine, Selenium, Vitamin B2 and Vitamin B3 enhance liver function and optimize levels of glutathione which helps cells fight off toxic challenges.
Joint Support - Vitamin E, Alpha-Lipoic Acid and
B Vitamins all contribute to joint support and controlling inflammation.
Antioxidant Status -Measures the nutrients that help prevent or repair cellular damage
caused by oxidation.
SPECTROX® measures the total antioxidant function of cells by measuring their ability to withstand oxidative stress.
MicroNutrient Testing is available now exclusively from SpectraCell Laboratories. This patented analysis measures levels of selected vitamins, minerals, antioxidants and other essential micronutrients within your white blood cells.www.SpectraCell.com
Metabolic Health - Vitamin B3, Vitamin B6, Vitamin B12 Vitamin E, Biotin, CoQ10, Chromium, Magnesium and Zinc all help the body handle daily sugar load, keeping systems responsive to insulin
and restoring lost insulin sensitivity.