Medicinal Plants and Cancer Research at St. Thomas University

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St Thomas University School of Science, Technology & Engineering Management Medicinal Plants And Cancer Research at STU Wim F.A. Steelant, CE, Ph.D., April 12 th , 2012

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Presented by Dr. Wim Steelant, Dean of the St. Thomas University School of Science, Technology, and Engineering Management. Part of the University Library's celebration of Earth Week 2012.

Transcript of Medicinal Plants and Cancer Research at St. Thomas University

Page 1: Medicinal Plants and Cancer Research at St. Thomas University

St Thomas UniversitySchool of Science, Technology& Engineering Management

Medicinal PlantsAnd

Cancer Research at STU

Wim F.A. Steelant, CE, Ph.D., April 12th , 2012

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Science Building

Carnival Cruise Lines Science & Technology Building

Wim F.A. Steelant, CE, Ph.D., April 12th , 2012

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Medicinal Plants

Why medicinal plants & cancer research ???

Wim F.A. Steelant, CE, Ph.D., April 12th , 2012

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Medicinal Plants

Ligusticum porteri & Anemopsis californica

Laboratory of Biochemical and Biomedical ResearchCreated in 2004, New Mexico, USA

Biomembrane Structure, Interaction and Signal Transduction

New Medicinal Agents against Diseases

- Native American Medicine man- Ketowa Indian (Cherokee Nation)- Folk medicine with local plants

Wim F.A. Steelant, CE, Ph.D., April 12th , 2012

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Importance of Medicinal Plants

• Common names: Loveroot, Porter’s Lovage, Osha,Chuchupate, and Wild Parsley• Location: In the West, Canada to MexicoEspecially the Rocky Mountain region

• Common names: Lizard Tail, Swamp Root, Yerba Mansa

• Common Location: Wet, swampy areas

Medicine man recommended two medicinal plants: Ligusticum porteri (Osha) and Anemopsis californica (Yerba Mansa)

Wim F.A. Steelant, CE, Ph.D., April 12th , 2012

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Willow tree Salicin Acetyl-salicylic acid

“Miracle drug”- pain/fever reducer- blood thinner against strokes- acts against cancer- acts against Alzheimer

Importance of Medicinal Plants

Wim F.A. Steelant, CE, Ph.D., April 12th , 2012

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Wim F.A. Steelant, CE, Ph.D., April 12th , 2012

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Importance of Medicinal Plants

Pacific Yew tree Paclitaxel/Taxol

Used in Cancer Chemotherapy- Discovered in 1967, due to a plant screening by the NCI- In 2000, 1.6 billion US$

Wim F.A. Steelant, CE, Ph.D., April 12th , 2012

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Importance of Medicinal Plants

Wim F.A. Steelant, CE, Ph.D., April 12th , 2012

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Flower

Leaf

Root

Importance of Medicinal Plants

Wim F.A. Steelant, CE, Ph.D., April 12th , 2012

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USDA-FS and STU

Wim F.A. Steelant, CE, Ph.D., April 12th , 2012

Ardesia crenata Pyrus calleryana

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Interdisciplinary!

Biological activity testing

AntibacterialAntifungal

Freeze-Dry

Anticancer

Harvest/Voucher specimen

Dried and ground plants

Leafs/roots/flowers

Extraction

Activity

Fractionation

Structure identification

Wim F.A. Steelant, CE, Ph.D., April 12th , 2012