Medical Imaging Modalities

14
The content of these slides by John Galeotti, © 2012-2013 Carnegie Mellon University (CMU), was made possible in part by NIH NLM contract# HHSN276201000580P, and is licensed under a Creative Commons Attribution 3.0 Unported License . To view a copy of this license, visit http://creativecommons.org/licenses/by/3.0/ or send a letter to Creative Commons, 171 2nd Street, Suite 300, San Francisco, California, 94105, USA. Permissions beyond the scope of this license may be available either from CMU or by emailing [email protected]. Medical Imaging Modalities Methods In Medical Image Analysis—Spring 2013 BioE 2630 (Pitt) : 16-725 (CMU RI) 18-791 (CMU ECE) : 42-735 (CMU BME) Dr. John Galeotti

description

Medical Imaging Modalities. Methods In Medical Image Analysis— Spring 2013 BioE 2630 (Pitt) : 16-725 (CMU RI) 18-791 (CMU ECE) : 42-735 (CMU BME) Dr. John Galeotti. Anatomical Axes. Superior = head Inferior = feet Anterior = front Posterior = back Proximal = central - PowerPoint PPT Presentation

Transcript of Medical Imaging Modalities

Page 1: Medical Imaging Modalities

The content of these slides by John Galeotti, © 2012-2013 Carnegie Mellon University (CMU), was made possible in part by NIH NLM contract# HHSN276201000580P, and is licensed under a Creative Commons Attribution 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by/3.0/ or send a letter to Creative Commons, 171 2nd Street, Suite 300, San Francisco, California, 94105, USA. Permissions beyond the scope of this license may be available either from CMU or by emailing [email protected] most recent version of these slides may be accessed online via http://itk.galeotti.net/

Medical Imaging Modalities

Methods In Medical Image Analysis—Spring 2013BioE 2630 (Pitt) : 16-725 (CMU RI)

18-791 (CMU ECE) : 42-735 (CMU BME)

Dr. John Galeotti

Page 2: Medical Imaging Modalities

2

Superior = headInferior = feet

Anterior = frontPosterior = back

Proximal = centralDistal = peripheral

Anatomical Axes

Page 3: Medical Imaging Modalities

3

Imaging Modalities

Camera: Microscope, Endoscope, etc.X-RayCTNuclear MedicineUltrasoundMRI…

Page 4: Medical Imaging Modalities

4

1896: The X-Ray

Page 5: Medical Imaging Modalities

5

Projection of X-Ray silhouette onto a detector

Measures densities3D maps to 2DDetectors often use an

intervening fluorescent screen to convert X-rays to visible light

Fat, muscle, bone, contrast agent, metal

X-Ray & Fluoroscopic Images

X-Ray Source

Patient

Bone

Detector

Page 6: Medical Imaging Modalities

6

Spin X-Ray source/detector around the patientFrom a series of projections, a tomographic image

is reconstructed using Filtered Back Projection.

Computerized Tomography

X-Ray Source

Patient

Bone

Detector

Spinsaroundpatient

Page 7: Medical Imaging Modalities

7

Nuclear Medicine

Previously discussed imaging modalities image anatomy (structure).

Nuclear medicine images physiology (function)At the cellular (and subcellular) level Technically a type of molecular imagingRequires use of radioactive pharmaceuticals

Page 8: Medical Imaging Modalities

8

Single Photon Emission Computed TomographyGamma camera for creating image of radioactive targetCamera is rotated around patient

SPECT

Patient

RadioactiveTarget

Array of Gamma Detectors

Spinsaroundpatient

Array of Lead Collimators

Page 9: Medical Imaging Modalities

9

Positron-emitting organic compounds create pairs of high energy photons that are detected synchronously.

No collimators, greater sensitivity. Attenuation is not location dependent, so quantification is

possible.

Positron Emission Tomography

+-

Patient

DetectorsWhen emitted positronscollide with electrons,their annihilation sends2 high-energy photonsoff in opposite directions

Page 10: Medical Imaging Modalities

10

Images anatomy

Ultrasound beam formed and steered by controlling the delay between the elements of the transducer array

Phased Array Ultrasound

Page 11: Medical Imaging Modalities

11

Real Time 3D Ultrasound

Page 12: Medical Imaging Modalities

12

Other Imaging Modalities

MRI & fMRI (will review later) OCT (“optical ultrasound”)Pathology (in addition to Radiology) Other modalities coming down the pike

Page 13: Medical Imaging Modalities

13

Current Trends in Imaging

3D, 4D, …Higher speed Greater resolution Measure function as well as structure Combining modalities (including direct vision)

Page 14: Medical Imaging Modalities

14

Dissection: Medical School, Day 1:

Meet the Cadaver. From Vesalius to the

Visible Human

The Gold Standard