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![Page 1: Mechanical Response of a Metallic Stent K. Ravi-Chandar and Renjun Wang Department of Aerospace Engineering and Engineering Mechanics Center for Mechanics.](https://reader035.fdocuments.in/reader035/viewer/2022062716/56649dbd5503460f94aaf6f6/html5/thumbnails/1.jpg)
Mechanical Response of a Metallic Stent
K. Ravi-Chandar and Renjun Wang
Department of Aerospace Engineering and Engineering Mechanics
Center for Mechanics of Solids, Structures and Materials
Collaborators: Prof. Suncica Canic, UH, Dr. Zvonko Krajcer, St. Luke’s
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Outline
Stents in vascular applications Failure modes Mechanics problem
Experimental characterization Analysis of the deformation
Coupled stent-artery deformation
Outlook
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Arteries
J Humphrey, Cardiovascular Solid Mechanics, Springer, 2002
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Abdominal Aortic Aneurysm
C.E. Ruiz, et al, Circulation, 1997;96:2438-2448
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Structural changes in the artery
Dramatic decrease in elastin and smooth muscle cell content
Increase in collagen Degradation of arterial resistance
to the blood pressure
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Treatment
Surgical placement of stent-grafts Extensive surgery – not all patients
are suitable for this procedure Endovascular placement of stents
and stent-grafts Quick, simple procedure – currently
still experimental Long-term consequences are not well
characterized
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AnueRx Bifurcated Stent
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WallStent
Villareal, Howell, and KrajcerTex Heart Inst J 2000;27:146-9
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Abdominal Aortic Aneurysm
Stent-graft Stent
C.E. Ruiz, et al, Circulation, 1995;91:2470-2477
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Abdominal Aortic Aneurysm
Short term
Reduction in the size of aneurysm
Long termDilation of proximal side of artery
Wever et al., (2000), European Journal of Vascular and Endovascular Surgery, 19: 197–201.
Endoleaks Chuter et al. (2001), Journal of Vascular Surgery, 34, 98–105.
Migration and other forms of failure Shames, Sanchez, Rubin and Sicard, (2002) Vascular and Endovascular Surgery, 36, 77-83
Bell (2002), Editorial, Vascular Medicine 7, 253–255
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Our Objectives
Evaluate the mechanical response of the stent in appropriate configurations – Experimental
Develop the appropriate structural mechanics description - Analytical
Evaluate the coupled response of the stent and the blood vessel - Analytical
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Experimental apparatus
Stent
Balloon
Pressure Meter
Air I n
Pressure Meter
Solid Tube
Air In
Balloon
Stent
Internal Pressure External Pressure
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Pressure-diameter relationship
-100
-50
0
50
100
150
0 5 10 15 20 25
Diameter - mm
Pre
ssu
re -
mm
of
Hg
Internal Pressure
External Pressure
No friction
with friction
Normal range of the aorta
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Pressure-length relationship
-100
-50
0
50
100
150
0 10 20 30 40 50 60 70 80
Length - mm
Pre
ssu
re -
mm
of
Hg
Internal Pressure
External Pressure
No friction
with friction
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Helical spring model – Kirchhoff-Love theory
a
r0, 0 – initial radius and pitch angle
r, – radius and pitch angle
Pa – axial force; Ps – transverse shear force
MB – bending moment; Mt – twisting moment
q – effect of pressure loading on the wire
Fz – external axial force
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Equilibrium equations
0cos
sincos
qrPP sa
zsa FPP cossin
0cos
sincossin)cossin(
2
2
qr
MMPPr tBsa
(1)
(2)
(3)
![Page 17: Mechanical Response of a Metallic Stent K. Ravi-Chandar and Renjun Wang Department of Aerospace Engineering and Engineering Mechanics Center for Mechanics.](https://reader035.fdocuments.in/reader035/viewer/2022062716/56649dbd5503460f94aaf6f6/html5/thumbnails/17.jpg)
Pressure loading
pn
rp
nl
rq
sin22
The internal pressure loading is distributed uniformly over the n wires, resulting in the load distribution q:
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Curvature and twist evolution
0
02
0
cos
r
0
000
cossin
r
0
022
0
coscos)(
rrEIEIM B
0
000
sincossincos)(
rrGIGIM ppt
r
2cos
r
cossin
Curvature:
Twist:
Bernoulli-Euler Beam Theory:
Coulomb Torsion Theory:
(4)
(5)
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Geometrical constraint
The braiding of the n wires results in contact at the cross-over points; these are constrained frictionally and therefore the wire is not allowed to unwind helically as the stent expands. This can be expressed as a constraint between the radius and the pitch angle of the helix:
0
0
coscos rr
(6)
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Pressure-diameter relationship
0
00
0
022
22
2
sincossincoscos
coscossin
sin2
cos
rrr
GI
rrr
EI
r
np
p
This is an exact relationship within the restrictions of the Kirchhoff-Love slender rod theory, without any adjustable parameters.
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Parameters of the stent
n Number of wires 36E Modulus of elasticity 200 GPaG Shear modulus 77 GPaa Radius of the stent wire 0.170 mPitch angle of the helix at zero pressure 34r Radius of the stent at zero pressure 0.01 m
L Length of the stent 0.08 m
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Effect of friction
Friction acts on the cylindrical surface of the stent in the axial direction, and is given by:
0
00
22200
03
sinsincos
coscossin
cossin2
cos
rGI
rEI
rnrr
np
p
rpF f 2
![Page 23: Mechanical Response of a Metallic Stent K. Ravi-Chandar and Renjun Wang Department of Aerospace Engineering and Engineering Mechanics Center for Mechanics.](https://reader035.fdocuments.in/reader035/viewer/2022062716/56649dbd5503460f94aaf6f6/html5/thumbnails/23.jpg)
Pressure-diameter relationship
-100
-50
0
50
100
150
0 5 10 15 20 25
Diameter - mm
Pre
ssu
re -
mm
of
Hg
Internal Pressure
External Pressure
No friction
with friction
![Page 24: Mechanical Response of a Metallic Stent K. Ravi-Chandar and Renjun Wang Department of Aerospace Engineering and Engineering Mechanics Center for Mechanics.](https://reader035.fdocuments.in/reader035/viewer/2022062716/56649dbd5503460f94aaf6f6/html5/thumbnails/24.jpg)
Pressure-length relationship
-100
-50
0
50
100
150
0 10 20 30 40 50 60 70 80
Length - mm
Pre
ssu
re -
mm
of
Hg
Internal Pressure
External Pressure
No friction
with friction
![Page 25: Mechanical Response of a Metallic Stent K. Ravi-Chandar and Renjun Wang Department of Aerospace Engineering and Engineering Mechanics Center for Mechanics.](https://reader035.fdocuments.in/reader035/viewer/2022062716/56649dbd5503460f94aaf6f6/html5/thumbnails/25.jpg)
Axial force measurements
Balloon
StentString
Pressure Meter
Air I n
Rigid Post
Weight
0
00
0
022
2
22 sincossincoscoscoscossin
cos
sin2
rrr
GI
rrr
EIp
n
rF p
z
![Page 26: Mechanical Response of a Metallic Stent K. Ravi-Chandar and Renjun Wang Department of Aerospace Engineering and Engineering Mechanics Center for Mechanics.](https://reader035.fdocuments.in/reader035/viewer/2022062716/56649dbd5503460f94aaf6f6/html5/thumbnails/26.jpg)
Axial force measurement
0
1
2
3
4
5
6
7
0 20 40 60 80 100 120 140 160 180
p - mm of Hg
Fz -
N
Theory
Experiment
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Spatially varying pressure – A beam-on-elastic-foundation model
x2r0
v(x)
r(x)
(a)
aeff prfxd
rdEI )(
4
4
~f(r)
![Page 28: Mechanical Response of a Metallic Stent K. Ravi-Chandar and Renjun Wang Department of Aerospace Engineering and Engineering Mechanics Center for Mechanics.](https://reader035.fdocuments.in/reader035/viewer/2022062716/56649dbd5503460f94aaf6f6/html5/thumbnails/28.jpg)
Governing differential equation
a
p
p
rrr
GI
rrr
EI
r
n
xd
rd
r
naE
0
00
0
022
22
2
4
44
cossincossincoscoscossin
sin2
cos
sin8
0 , dx
drRrFixed boundary:
Free boundary:
Compliant boundary:
0 ,02
2
3
3
dx
rd
dx
rd
vesselstentvesselstent dx
dr
dx
drrr ,
![Page 29: Mechanical Response of a Metallic Stent K. Ravi-Chandar and Renjun Wang Department of Aerospace Engineering and Engineering Mechanics Center for Mechanics.](https://reader035.fdocuments.in/reader035/viewer/2022062716/56649dbd5503460f94aaf6f6/html5/thumbnails/29.jpg)
Example 1 –Fixed ends
String
Clamp
Plastic Block
Air I n
Stent
Balloon
Metallic Tube
![Page 30: Mechanical Response of a Metallic Stent K. Ravi-Chandar and Renjun Wang Department of Aerospace Engineering and Engineering Mechanics Center for Mechanics.](https://reader035.fdocuments.in/reader035/viewer/2022062716/56649dbd5503460f94aaf6f6/html5/thumbnails/30.jpg)
Comparison to experiments
0.8
0.9
1
1.1
1.2
0 0.2 0.4 0.6 0.8 1
x/L
r/R
ExperimentalData
Beam on elastic foundation modeln
![Page 31: Mechanical Response of a Metallic Stent K. Ravi-Chandar and Renjun Wang Department of Aerospace Engineering and Engineering Mechanics Center for Mechanics.](https://reader035.fdocuments.in/reader035/viewer/2022062716/56649dbd5503460f94aaf6f6/html5/thumbnails/31.jpg)
Example 2 – stent exiting a catheter
0
5
10
15
0 10 20 30 40 50 60 70 80
x - mm
r -
mm
Experimental Data
Beam on elastic foundation model
![Page 32: Mechanical Response of a Metallic Stent K. Ravi-Chandar and Renjun Wang Department of Aerospace Engineering and Engineering Mechanics Center for Mechanics.](https://reader035.fdocuments.in/reader035/viewer/2022062716/56649dbd5503460f94aaf6f6/html5/thumbnails/32.jpg)
Coupled response of the aorta and stent
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Response of the aorta
Curve fit to data from:Länne T et al 1992, Noninvasive measurement of diameter changes in the distal abdominal aorta in man, Ultrasound in Med & Biol,18:451-457.
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Coupled response - results
5
7
9
11
13
-15 0 15 30 45 60 75
Axial Position(mm)
Rad
ius
(mm
)
AortaAorta
Stent
Aneurysm RLa
RHa
Aorta
PH=150mmHgPL=65mmHgRH
a=8.73mmRL
a=7.75mm
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Summary
Experimental methods developed to evaluate the mechanical response of stentsAnalytical models were developed to characterize the response of the stent by itself and coupled with the aortaThe procedures established should enable design of AAA stentsProf Canic is working on embedding these models with fluid flow simulations
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Dilation of the aorta
Source:Wever et al., (2000), European Journal of Vascular and Endovascular Surgery, 19: 197–201.