MBV2010/BIO2140

Colloquium, May 7

RULES

• Multiple choice• Only one correct answer• 30-60 seconds to answer• No textbook, computer, mobile phone, please

There will be a prize for the group with the most correct answers.

A eukaryotic gene is most likely to be transcribed if it is located in

A Telomeres

B Heterochromatin

C Euchromatin

D Centromeres

1

A eukaryotic gene is most likely to be transcribed if it is located in

A Telomeres

B Heterochromatin

C Euchromatin

D Centromeres

1

Riboswitches

A Are found in RNA

B Are found in DNA

C Regulate only transcription

D Regulate only translation

2

Riboswitches

A Are found in RNA

B Are found in DNA

C Regulate only transcription

D Regulate only translation

2

Pre-microRNAs can be encoded in

A introns

B noncoding regions of a gene

C coding regions

D all of the above

3

Pre-microRNAs can be encoded in

A introns

B noncoding sequences

C coding regions

D all of the above

3

MicroRNA genes are transcribed by

A RNA polymerase I

B RNA polymerase II

C RNA polymerase III

D RNA polymerase V

4

MicroRNA genes are transcribed by

A RNA polymerase I

B RNA polymerase II

C RNA polymerase III

D RNA polymerase V

4

Which proteins make up the Microprocessorcomplex?

A Pasha and Drosha

B Dicer and Drosha

C Dicer and Argonaute

D Pasha and Dicer

5

Which proteins make up the Microprocessorcomplex?

A Pasha and Drosha

B Dicer and Drosha

C Dicer and Argonaute

D Pasha and Dicer

5

Which proteins have a PAZ domain?

A Drosha and Dicer

B Dicer and Argonaute

C Argonaute and Drosha

D Drosha and Pasha

6

PAZ stands for three proteins that contain thisdomain.

Which proteins have a PAZ domain?

A Drosha and Dicer

B Dicer and Argonaute

C Argonaute and Drosha

D Drosha and Pasha

6PAZ stands for three proteins that contain this domain: Piwi, Argonaute, and Zwille

The long noncoding RNA Xist

A functions in the cytoplasm

B is transcribed from a gene called Tsix

C coats the chromosome it is transcribed from

D induces formation of euchromatin

7

The long noncoding RNA Xist

A functions in the cytoplasm

B is transcribed from a gene called Tsix

C coats the chromosome it is transcribed from

D induces formation of euchromatin

7

Gal80

A is a regulator of transcription

B is a repressor of transcription

C binds to DNA

D binds to RNA

8

Gal4

Gal80

A is a regulator of transcription

B is a repressor of transcription

C binds to DNA

D binds to RNA

8

PIWI-interaction RNAs (piRNAs)

A are bound by the RISC complex

B are about 200 nucleotides long

C are present in prokaryotes

D regulate transcription

9

PIWI-interaction RNAs (piRNAs)

A are bound by the RISC complex

B are about 200 nucleotides long

C are present in prokaryotes

D regulate transcription

9

The size of microRNAs varies between

A 11-17 nucleotides

B 19-25 nucleotides

C 22-28 nucleotides

D 25-30 nucleotides

10

The size of microRNAs varies between

A 11-17 nucleotides

B 19-25 nucleotides

C 22-28 nucleotides

D 25-30 nucleotides

10

Polycomb

A is a repressor of transcription

B is an activator of transcription

C methylates DNA

D deacetylates histones

11

Polycomb

A is a repressor of transcription

B is an activator of transcription

C methylates DNA

D deacetylates histones

11