60 WWW.MAXMUSCLE.COM ı AUGUST 2014

Dairy Products May Be Most Efective in Targeting Metabolic Syndrome (MetS)MetS is characterized by obesity, dyslipidemias, hypertension and hyperglycemia,

and impacts 34 percent of the U.S. adult population. Nutrition scientists at the

University of Connecticut, Storrs evaluated data from epidemiological studies and

clinical interventions suggesting that one or more dairy components might directly affect

MetS parameters. Researchers found that calcium reduces

body weight by modulating vitamin D concentrations in

plasma and activating genes involved in fatty acid synthesis

and reducing those involved in lipolysis. Peptides present in

milk have been associated with blood pressure reductions.

BCAAs may increase post-prandial insulin secretion

and regulate plasma glucose levels, and leucine, an

abundant amino acid in milk, may be responsible

for decreased plasma glucose through modulation of

mTOR. Through different proposed mechanisms, dairy

nutrients may target all components of MetS. (Dugan CE,

Fernandez ML. Yale J Biol Med. 2014 Jun 6;87(2):135-

147). MMSN Featured Product: MaxPro

SCIENCENEWS By Dr. Phil Harvey, PhD, RD, FISSN, FACN

Phosphatidic Acid (PA) Signifcantly Improves Muscle Hypertrophy, Lean Body Mass and Maximum Strength In this landmark study, top

sports science researchers at

the University of Tampa set out

to compare the effects of PA to

stimulate mTOR signaling and

its ability to augment resistance

training-induced changes in body

composition and performance.

Trained subjects consumed either

750 mg PA daily or placebo and

each took part in an 8 week

periodized resistance training

program. Results showed that PA

signifcantly increased lean body

mass (+2.4 kg), cross sectional

area (+1.0 cm), and leg press

strength (+51.9 kg) over placebo.

Researchers concluded that PA

signifcantly activates mTOR and

signifcantly improved responses in

skeletal muscle hypertrophy, lean

body mass and maximal strength

to resistance exercise. (Joy JM,

Gundermann DM, Lowery RP, et

al. Nutr & Metab. 2014;11:29 doi:

10.1186/1743-7075-11-29). MMSN

Featured Product: MaxxTOR

Pyrroloquinoline Quinone (PQQ) Infuences Mitochondrial Energy-Related MetabolismScientists at University of California, Davis set out to evaluate the

effects of PQQ on mitochondrial energy-related

metabolism. Two studies were conducted that

included 10 subjects (5 females, 5 males) each

taking PQQ administered as a daily dose.

PQQ supplementation resulted in signifcant

antioxidant function (TBAR) and decreases in

indices of infammation (C-reactive protein,

IL-6, and urinary methylated amines, and

N-oxide) consistent with enhanced mitochondria-

related functions. All standard clinical indices

were normal. The data are among the frst to

link systemic effects of PQQ to corresponding

mitochondrial energy-related metabolic effects in

humans. (Harris CB, Chowanadisai W, Mishchuk

DO, et al. J Nutr Biochem. 2013 Dec;24(12):2076-

84. MMSN Featured Product: MiTOR